|
Name |
Accession |
Description |
Interval |
E-value |
| GLECT |
cd00070 |
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ... |
129-256 |
2.37e-53 |
|
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.
Pssm-ID: 238025 Cd Length: 127 Bit Score: 168.97 E-value: 2.37e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 129 PYDMPLPGGVMPRMLITIIGTVKPNANSITLNFKKGN-DIAFHFNPRFNENnrrVIVCNTKQDNNWGREERQSAFPFESG 207
Cdd:cd00070 1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 13929190 208 KPFKIQVLVEADHFKVAVNDVHLLQYNHRMKnLREISQLGIIGDITLTS 256
Cdd:cd00070 78 QPFELTILVEEDKFQIFVNGQHFFSFPHRLP-LESIDYLSINGDVSLTS 125
|
|
| Gal-bind_lectin |
smart00908 |
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ... |
135-256 |
3.29e-53 |
|
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.
Pssm-ID: 214904 Cd Length: 122 Bit Score: 168.54 E-value: 3.29e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 135 PGGVMPRMLITIIGTVKPNANSITLNFKKG--NDIAFHFNPRFNENnrrVIVCNTKQDNNWGREERQSAFPFESGKPFKI 212
Cdd:smart00908 1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDEG---TIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 13929190 213 QVLVEADHFKVAVNDVHLLQYNHRMKnLREISQLGIIGDITLTS 256
Cdd:smart00908 78 EILVEEDEFKVAVNGQHFLEFPHRLP-LESIDTLEISGDVQLTS 120
|
|
| Gal-bind_lectin |
pfam00337 |
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ... |
135-256 |
2.37e-49 |
|
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).
Pssm-ID: 459768 Cd Length: 124 Bit Score: 158.57 E-value: 2.37e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 135 PGGVMPRMLITIIGTVKPNANSITLNFKKG----NDIAFHFNPRFNENnrrVIVCNTKQDNNWGREERQSAFPFESGKPF 210
Cdd:pfam00337 1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 13929190 211 KIQVLVEADHFKVAVNDVHLLQYNHRMKNlREISQLGIIGDITLTS 256
Cdd:pfam00337 78 ELTILVGDDHFKIYVNGQHFTTFKHRLPP-EDIDALQVRGDVKLTS 122
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-137 |
1.23e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 52.30 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 9 DALAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 13929190 89 FPGQPGGPGAYPSAPGAYPSAPGAYPATG---PFGAPTGPLTVPYDMPLPGG 137
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQAAQGasaPSPAADDPVPLPPEPDDPPD 750
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
46-129 |
2.04e-04 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 42.16 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 46 GQAPpggYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAP-GAYPSAPGAYPATGPFGAPTG 124
Cdd:cd23959 151 GQLP---MFGQHPPPAKPLPAAAAAQQSSASPGEVASPFASGTVSASPFATATDTAPSsGAPDGFPAEASAPSPFAAPAS 227
|
....*
gi 13929190 125 PLTVP 129
Cdd:cd23959 228 AASFP 232
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
17-128 |
9.61e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 40.18 E-value: 9.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 17 PNPRGWPGAWGNQPGAGGYPGASYPGAypgqapPGGYPGQAPpsaYPGPTGPSAYPGPTAPGaypgPTAPGAFPGQPGGP 96
Cdd:TIGR01628 386 PMGSPMGGAMGQPPYYGQGPQQQFNGQ------PLGWPRMSM---MPTPMGPGGPLRPNGLA----PMNAVRAPSRNAQN 452
|
90 100 110
....*....|....*....|....*....|..
gi 13929190 97 GAYPSAPGAYPSAPGAYPATGPFGAPTGPLTV 128
Cdd:TIGR01628 453 AAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTA 484
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
12-126 |
9.63e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 40.05 E-value: 9.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 12 AGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPG--AYPGPTAPGAF 89
Cdd:COG5180 345 ASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNGAPQPGLGRRGAPGPPMGAGDLVqaALDGGGRETAS 424
|
90 100 110
....*....|....*....|....*....|....*..
gi 13929190 90 PGQPGGPGAYPsaPGAYPSAPGAYPATGPFGAPTGPL 126
Cdd:COG5180 425 LGGAAGGAGQG--PKADFVPGDAESVSGPAGLADQAG 459
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
48-136 |
2.45e-03 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 38.83 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 48 APPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGqpggPGAYPSAPGAYPSAPGAypATGPFGAPTGPLT 127
Cdd:NF041121 19 AAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPL----PAPYPGSLAPPPPPPPG--PAGAAPGAALPVR 92
|
....*....
gi 13929190 128 VPYDMPLPG 136
Cdd:NF041121 93 VPAPPALPN 101
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
29-142 |
2.49e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 38.98 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 29 QPGAGGYPGASYPGAYPGQA-PPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTA-------PGAFPGQPGGPGAYP 100
Cdd:pfam03154 246 HPPLQPMTQPPPPSQVSPQPlPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQssqsqvpPGPSPAAPGQSQQRI 325
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 13929190 101 SAPGAYPSA-PGAYPATGPFgaPTGPLTVPYDMPLPGGVMPRM 142
Cdd:pfam03154 326 HTPPSQSQLqSQQPPREQPL--PPAPLSMPHIKPPPTTPIPQL 366
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GLECT |
cd00070 |
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ... |
129-256 |
2.37e-53 |
|
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.
Pssm-ID: 238025 Cd Length: 127 Bit Score: 168.97 E-value: 2.37e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 129 PYDMPLPGGVMPRMLITIIGTVKPNANSITLNFKKGN-DIAFHFNPRFNENnrrVIVCNTKQDNNWGREERQSAFPFESG 207
Cdd:cd00070 1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 13929190 208 KPFKIQVLVEADHFKVAVNDVHLLQYNHRMKnLREISQLGIIGDITLTS 256
Cdd:cd00070 78 QPFELTILVEEDKFQIFVNGQHFFSFPHRLP-LESIDYLSINGDVSLTS 125
|
|
| Gal-bind_lectin |
smart00908 |
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ... |
135-256 |
3.29e-53 |
|
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.
Pssm-ID: 214904 Cd Length: 122 Bit Score: 168.54 E-value: 3.29e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 135 PGGVMPRMLITIIGTVKPNANSITLNFKKG--NDIAFHFNPRFNENnrrVIVCNTKQDNNWGREERQSAFPFESGKPFKI 212
Cdd:smart00908 1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDEG---TIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 13929190 213 QVLVEADHFKVAVNDVHLLQYNHRMKnLREISQLGIIGDITLTS 256
Cdd:smart00908 78 EILVEEDEFKVAVNGQHFLEFPHRLP-LESIDTLEISGDVQLTS 120
|
|
| Gal-bind_lectin |
pfam00337 |
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ... |
135-256 |
2.37e-49 |
|
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).
Pssm-ID: 459768 Cd Length: 124 Bit Score: 158.57 E-value: 2.37e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 135 PGGVMPRMLITIIGTVKPNANSITLNFKKG----NDIAFHFNPRFNENnrrVIVCNTKQDNNWGREERQSAFPFESGKPF 210
Cdd:pfam00337 1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 13929190 211 KIQVLVEADHFKVAVNDVHLLQYNHRMKNlREISQLGIIGDITLTS 256
Cdd:pfam00337 78 ELTILVGDDHFKIYVNGQHFTTFKHRLPP-EDIDALQVRGDVKLTS 122
|
|
| GLECT |
smart00276 |
Galectin; Galectin - galactose-binding lectin |
133-258 |
1.11e-48 |
|
Galectin; Galectin - galactose-binding lectin
Pssm-ID: 214596 Cd Length: 128 Bit Score: 157.00 E-value: 1.11e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 133 PLPGGVMPRMLITIIGTVKPNANSITLNFKKGN-DIAFHFNPRFNENnrrVIVCNTKQDNNWGREERQSAFPFESGKPFK 211
Cdd:smart00276 4 PIPGGLKPGQTLTVRGIVLPDAKRFSINLLTGGdDIALHFNPRFNEN---KIVCNSKLNGSWGSEEREGGFPFQPGQPFD 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 13929190 212 IQVLVEADHFKVAVNDVHLLQYNHRMKNLrEISQLGIIGDITLTSAS 258
Cdd:smart00276 81 LTIIVQPDHFQIFVNGVHITTFPHRLPLE-SIDYLSINGDVQLTSVS 126
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-137 |
1.23e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 52.30 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 9 DALAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 13929190 89 FPGQPGGPGAYPSAPGAYPSAPGAYPATG---PFGAPTGPLTVPYDMPLPGG 137
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQAAQGasaPSPAADDPVPLPPEPDDPPD 750
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
6-127 |
1.86e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 51.60 E-value: 1.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 6 SLNDALAGSGNPNPRGWPGawgnqPGAGGY-----PGASYP-GAYP--GQAPPGGYPGQAPPSAYPGPTGP--SAYPGPT 75
Cdd:PRK14959 370 SLRPSGGGASAPSGSAAEG-----PASGGAatiptPGTQGPqGTAPaaGMTPSSAAPATPAPSAAPSPRVPwdDAPPAPP 444
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 13929190 76 APG--AYPGPTAPGAFPGqPGGPGAYPSAPGAYPSApGAYPATGPFgAPTGPLT 127
Cdd:PRK14959 445 RSGipPRPAPRMPEASPV-PGAPDSVASASDAPPTL-GDPSDTAEH-TPSGPRT 495
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
10-125 |
7.25e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.98 E-value: 7.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 10 ALAGSGNPNPRGW-PGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK07764 594 AAGGEGPPAPASSgPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKA 673
|
90 100 110
....*....|....*....|....*....|....*..
gi 13929190 89 FPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGP 125
Cdd:PRK07764 674 GGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPP 710
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
21-129 |
1.47e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.83 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 21 GWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYP 100
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDG 668
|
90 100
....*....|....*....|....*....
gi 13929190 101 SAPGAYPSAPGAYPATGPFGAPTGPLTVP 129
Cdd:PRK07764 669 WPAKAGGAAPAAPPPAPAPAAPAAPAGAA 697
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
31-122 |
2.90e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.06 E-value: 2.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 31 GAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPSAP 110
Cdd:PRK07764 389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAP 468
|
90
....*....|..
gi 13929190 111 GAYPATGPFGAP 122
Cdd:PRK07764 469 APAAAPEPTAAP 480
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
24-129 |
4.43e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.67 E-value: 4.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 24 GAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGA----Y 99
Cdd:PRK07764 665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVplppE 744
|
90 100 110
....*....|....*....|....*....|
gi 13929190 100 PSAPGAYPSAPGAYPATGPFGAPTGPLTVP 129
Cdd:PRK07764 745 PDDPPDPAGAPAQPPPPPAPAPAAAPAAAP 774
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-122 |
7.09e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.90 E-value: 7.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 9 DALAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK07764 668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDD 747
|
90 100 110
....*....|....*....|....*....|....*
gi 13929190 89 FPGQPGGPGAYPSAPGAYP-SAPGAYPATGPFGAP 122
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPaAAPAAAPPPSPPSEE 782
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
10-140 |
7.69e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.90 E-value: 7.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 10 ALAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAF 89
Cdd:PRK07764 642 APAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQP 721
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 13929190 90 PGQPGGPGAYPSAPGAY---PSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMP 140
Cdd:PRK07764 722 PQAAQGASAPSPAADDPvplPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
32-137 |
8.26e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.52 E-value: 8.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 32 AGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAyPGPTAPGAFPGQPGGPGAYPSAPGAYPSA-P 110
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAA-PAEASAAPAPGVAAPEHHPKHVAVPDASDgG 666
|
90 100
....*....|....*....|....*..
gi 13929190 111 GAYPATGPFGAPTGPLTVPYDMPLPGG 137
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAP 693
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
11-140 |
9.02e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.86 E-value: 9.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 11 LAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPpggyPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAfP 90
Cdd:PHA03247 2695 LTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASP----ALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPA-P 2769
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 13929190 91 GQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMP 140
Cdd:PHA03247 2770 APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP 2819
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
7-141 |
9.52e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.86 E-value: 9.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 7 LNDALAGSGNPnPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAP 86
Cdd:PHA03247 2520 LPDEPVGEPVH-PRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARP 2598
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13929190 87 GAfPGQPGGPGAYPSAPGAYPSA------------PGAYPATGPFGAPTGPLTVPYDMPLPGGVMPR 141
Cdd:PHA03247 2599 RA-PVDDRGDPRGPAPPSPLPPDthapdppppspsPAANEPDPHPPPTVPPPERPRDDPAPGRVSRP 2664
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-125 |
1.21e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 1.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 9 DALAGSGNPNPRGWPGAWGNQPGAggyPGAsyPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGa 88
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAAR---PAA--PAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD- 664
|
90 100 110
....*....|....*....|....*....|....*..
gi 13929190 89 fPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGP 125
Cdd:PRK07764 665 -GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQ 700
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
49-141 |
1.33e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.08 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 49 PPGGYPGQAPP---SAYPGPTGPS----AYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGA 121
Cdd:PHA03247 2703 PPPPTPEPAPHalvSATPLPPGPAaarqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRR 2782
|
90 100
....*....|....*....|
gi 13929190 122 PTGPLTVPYDMPLPGGVMPR 141
Cdd:PHA03247 2783 LTRPAVASLSESRESLPSPW 2802
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
12-136 |
1.41e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 12 AGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPG 91
Cdd:PRK07764 616 AAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAG 695
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 13929190 92 QPGGPGAyPSAPGAYPSAPGAYPATGPFGAPTGPLTVP----YDMPLPG 136
Cdd:PRK07764 696 AAPAQPA-PAPAATPPAGQADDPAAQPPQAAQGASAPSpaadDPVPLPP 743
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
41-136 |
1.46e-05 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 45.97 E-value: 1.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 41 PGAYPGQAPPGGYPG-QAPPSAYPGPTGPSAYPGPTA----PGAYPGPTAPGAFPG-----QPGGPGAYPSAPGAYP--S 108
Cdd:PRK14086 90 PSAGEPAPPPPHARRtSEPELPRPGRRPYEGYGGPRAddrpPGLPRQDQLPTARPAypayqQRPEPGAWPRAADDYGwqQ 169
|
90 100
....*....|....*....|....*....
gi 13929190 109 APGAYPATGPFGAPTGPLTVP-YDMPLPG 136
Cdd:PRK14086 170 QRLGFPPRAPYASPASYAPEQeRDREPYD 198
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
11-125 |
2.27e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 2.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 11 LAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFP 90
Cdd:PRK07764 387 VAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466
|
90 100 110
....*....|....*....|....*....|....*
gi 13929190 91 GqPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGP 125
Cdd:PRK07764 467 A-PAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAP 500
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
20-125 |
2.39e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 2.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 20 RGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAyPGPTAPGAFPGQPGGPGAY 99
Cdd:PRK07764 383 RRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPP-SPAGNAPAGGAPSPPPAAA 461
|
90 100
....*....|....*....|....*.
gi 13929190 100 PSAPGAYPSAPGAYPATGPFGAPTGP 125
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAA 487
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
12-151 |
2.78e-05 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 45.06 E-value: 2.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 12 AGSGNPNPRGWPGAWGNQPGAGGYPgASYPGAYPGQA-PPGGYPGQA-PPSAYPGPTG-PSAYPGPTAP------GAYPG 82
Cdd:PHA03378 679 TGANTMLPIQWAPGTMQPPPRAPTP-MRPPAAPPGRAqRPAAATGRArPPAAAPGRARpPAAAPGRARPpaaapgRARPP 757
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13929190 83 PTAPGAFPGQPGGPGAypSAPGAYPSAPGAyPATGPFGAPTgPLTVPYDMPLPGGVMPRMLITIIGTVK 151
Cdd:PHA03378 758 AAAPGRARPPAAAPGA--PTPQPPPQAPPA-PQQRPRGAPT-PQPPPQAGPTSMQLMPRAAPGQQGPTK 822
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
33-137 |
4.53e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.59 E-value: 4.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 33 GGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPSAPGA 112
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSA 464
|
90 100
....*....|....*....|....*
gi 13929190 113 YPATGPfGAPTGPLTVPYDMPLPGG 137
Cdd:PRK07764 465 QPAPAP-AAAPEPTAAPAPAPPAAP 488
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
23-129 |
5.36e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.10 E-value: 5.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 23 PGAWGNQPGAGGYPGASYP-GAYPGQAPPGGYPGQAPPSAYPGPTgPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPS 101
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPaAAAPAPAAPPAAPAAAPAAAAAARA-VAAAPARRSPAPEALAAARQASARGPGGAPAPAP 452
|
90 100
....*....|....*....|....*...
gi 13929190 102 APGAYPSAPGAYPATGPFGAPTGPLTVP 129
Cdd:PRK12323 453 APAAAPAAAARPAAAGPRPVAAAAAAAP 480
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
45-123 |
7.92e-05 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 43.73 E-value: 7.92e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13929190 45 PGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPT 123
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDE 116
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
10-126 |
9.69e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 9.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 10 ALAGSGNPNPRGWPGAWGNqPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAF 89
Cdd:PHA03247 2747 GPATPGGPARPARPPTTAG-PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA 2825
|
90 100 110
....*....|....*....|....*....|....*..
gi 13929190 90 PGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGPL 126
Cdd:PHA03247 2826 GPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDV 2862
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
4-128 |
1.45e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.67 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 4 GFSLNDALAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGP 83
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ 465
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 13929190 84 TAPGAFPGQPGGPGAYPSAPGAYPSAPGAYPATGPfGAPTGPLTV 128
Cdd:PRK07764 466 PAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAP-AAPAGADDA 509
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
46-129 |
2.04e-04 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 42.16 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 46 GQAPpggYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAP-GAYPSAPGAYPATGPFGAPTG 124
Cdd:cd23959 151 GQLP---MFGQHPPPAKPLPAAAAAQQSSASPGEVASPFASGTVSASPFATATDTAPSsGAPDGFPAEASAPSPFAAPAS 227
|
....*
gi 13929190 125 PLTVP 129
Cdd:cd23959 228 AASFP 232
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
14-152 |
2.18e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 14 SGNPNPRGWPGAWGNQPGAGGYPGASYPGAYP----GQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAyPGPTAPGAF 89
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVPAGPatpgGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRP-AVASLSESR 2795
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13929190 90 PGQPGGPGAYPSAPGAYPSAPGAYPATGPFG-APTGPLTVPYDMPLPGGVMPRMLiTIIGTVKP 152
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPPAASPAGpLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAP 2858
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
17-140 |
3.26e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 17 PNPRGWPGAWGNQPGAGGyPGASYPGAYPGQAPPggyPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGP 96
Cdd:PHA03247 2710 PAPHALVSATPLPPGPAA-ARQASPALPAAPAPP---AVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTR 2785
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 13929190 97 GAYPSAPGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMP 140
Cdd:PHA03247 2786 PAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
43-141 |
3.69e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 43 AYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAP 122
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665
|
90
....*....|....*....
gi 13929190 123 TGPLTVPYDMPLPGGVMPR 141
Cdd:PRK07764 666 GDGWPAKAGGAAPAAPPPA 684
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-137 |
3.89e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 3.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 9 DALAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGG--YPGQAPPSAYPGPTGPSAYPGPT-APGAYPGPTA 85
Cdd:PRK07764 626 APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWpaKAGGAAPAAPPPAPAPAAPAAPAgAAPAQPAPAP 705
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 13929190 86 PGAFPGQPGgpgayPSAPGAYPSAPGAYPATGPFGAPTGPL-TVPYDMPLPGG 137
Cdd:PRK07764 706 AATPPAGQA-----DDPAAQPPQAAQGASAPSPAADDPVPLpPEPDDPPDPAG 753
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-125 |
4.10e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 4.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 9 DALAGSGNPNPRGWPGAWGNQPGAGGYPGASY-PGAYPGQAPPG-GYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAP 86
Cdd:PRK07764 379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPaPAAAAPAAAAApAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPP 458
|
90 100 110
....*....|....*....|....*....|....*....
gi 13929190 87 GAFPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGP 125
Cdd:PRK07764 459 AAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAP 497
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
46-129 |
4.86e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 41.41 E-value: 4.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 46 GQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGA-FPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTG 124
Cdd:PRK12270 35 DYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAaAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVE 114
|
....*
gi 13929190 125 PLTVP 129
Cdd:PRK12270 115 DEVTP 119
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
27-121 |
5.81e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 41.03 E-value: 5.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 27 GNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAypgPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAY 106
Cdd:PRK12270 35 DYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAA---PAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAA 111
|
90
....*....|....*
gi 13929190 107 PSAPGAYPATGPFGA 121
Cdd:PRK12270 112 AVEDEVTPLRGAAAA 126
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
29-138 |
6.89e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 40.63 E-value: 6.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 29 QPGAGGyPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPS 108
Cdd:PRK12323 364 RPGQSG-GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASAR 442
|
90 100 110
....*....|....*....|....*....|
gi 13929190 109 APGAYPATGPFGAPTGPLTVPYDMPLPGGV 138
Cdd:PRK12323 443 GPGGAPAPAPAPAAAPAAAARPAAAGPRPV 472
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
17-154 |
7.06e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.08 E-value: 7.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 17 PNPRGWPGAWGN-----QPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAfPG 91
Cdd:PHA03247 2683 PRRRAARPTVGSltslaDPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPAR-PP 2761
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 13929190 92 QPGGPG--AYPSAPGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMPRMLITIIGTVKPNA 154
Cdd:PHA03247 2762 TTAGPPapAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
23-136 |
7.20e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 40.63 E-value: 7.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 23 PGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYP-------GPTGPSAYPGPT-APGAYPGPTAPGAFPGQPG 94
Cdd:PRK12323 392 PAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEAlaaarqaSARGPGGAPAPApAPAAAPAAAARPAAAGPRP 471
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 13929190 95 GPGAYPSAPGayPSAPGAYPATGPFGAPTGPlTVPYDMPLPG 136
Cdd:PRK12323 472 VAAAAAAAPA--RAAPAAAPAPADDDPPPWE-ELPPEFASPA 510
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
12-140 |
9.30e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.69 E-value: 9.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 12 AGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGayPGPTAPGAFPG 91
Cdd:PHA03247 2734 ALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS--PWDPADPPAAV 2811
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 13929190 92 QPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGPltVPYDMPLPGGVMP 140
Cdd:PHA03247 2812 LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP--PPPSLPLGGSVAP 2858
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
17-128 |
9.61e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 40.18 E-value: 9.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 17 PNPRGWPGAWGNQPGAGGYPGASYPGAypgqapPGGYPGQAPpsaYPGPTGPSAYPGPTAPGaypgPTAPGAFPGQPGGP 96
Cdd:TIGR01628 386 PMGSPMGGAMGQPPYYGQGPQQQFNGQ------PLGWPRMSM---MPTPMGPGGPLRPNGLA----PMNAVRAPSRNAQN 452
|
90 100 110
....*....|....*....|....*....|..
gi 13929190 97 GAYPSAPGAYPSAPGAYPATGPFGAPTGPLTV 128
Cdd:TIGR01628 453 AAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTA 484
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
12-126 |
9.63e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 40.05 E-value: 9.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 12 AGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPG--AYPGPTAPGAF 89
Cdd:COG5180 345 ASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNGAPQPGLGRRGAPGPPMGAGDLVqaALDGGGRETAS 424
|
90 100 110
....*....|....*....|....*....|....*..
gi 13929190 90 PGQPGGPGAYPsaPGAYPSAPGAYPATGPFGAPTGPL 126
Cdd:COG5180 425 LGGAAGGAGQG--PKADFVPGDAESVSGPAGLADQAG 459
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
36-142 |
9.81e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.31 E-value: 9.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 36 PGASYPGAYPGQAPPGGYPGQAPPSAYP-GPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPSAPGAYP 114
Cdd:PHA03247 2894 STESFALPPDQPERPPQPQAPPPPQPQPqPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVA 2973
|
90 100 110
....*....|....*....|....*....|.
gi 13929190 115 AT---GPFGAPTGPLTVPYDMPLPGGVMPRM 142
Cdd:PHA03247 2974 VPrfrVPQPAPSREAPASSTPPLTGHSLSRV 3004
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
36-150 |
9.96e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.08 E-value: 9.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 36 PGASYPGAYP-GQAPPGGYPGQAPPSAYPGPTGPSAYPGPtAPGAYPGPTAPGAFPGqpggPGAYPSAPGAYPSAPGA-- 112
Cdd:PRK14951 384 PEAAAPAAAPvAQAAAAPAPAAAPAAAASAPAAPPAAAPP-APVAAPAAAAPAAAPA----AAPAAVALAPAPPAQAApe 458
|
90 100 110
....*....|....*....|....*....|....*...
gi 13929190 113 YPATGPFGAPTGPLTVPYDMPLPGGVMPRMLITIIGTV 150
Cdd:PRK14951 459 TVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDV 496
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
13-140 |
1.15e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 39.86 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 13 GSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQ 92
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAP 450
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 13929190 93 PGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMP 140
Cdd:PRK12323 451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP 498
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
37-128 |
1.30e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 39.72 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 37 GASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSA--------YPGPTAPGAyPGPTAPGAFPGQPGGPGayPSAPGAYPS 108
Cdd:PRK14965 380 GAPAPPSAAWGAPTPAAPAAPPPAAAPPVPPAAParpaaarpAPAPAPPAA-AAPPARSADPAAAASAG--DRWRAFVAF 456
|
90 100
....*....|....*....|
gi 13929190 109 APGAYPATGPFGAPTGPLTV 128
Cdd:PRK14965 457 VKGKKPALGASLEQGSPLGV 476
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
30-133 |
1.42e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 39.83 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 30 PGAGGYPGASYPGAYPGQAPPggyPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTA-----PGAFPGQPGGPGAYPSAPG 104
Cdd:PRK07003 362 VTGGGAPGGGVPARVAGAVPA---PGARAAAAVGASAVPAVTAVTGAAGAALAPKAaaaaaATRAEAPPAAPAPPATADR 438
|
90 100
....*....|....*....|....*....
gi 13929190 105 AYPSAPGAYPATGPFGAPTGPLTVPYDMP 133
Cdd:PRK07003 439 GDDAADGDAPVPAKANARASADSRCDERD 467
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
23-115 |
1.45e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 39.92 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 23 PGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSA 102
Cdd:PHA03247 394 PFARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPERQPPAPATEPAPDDPDDATRKA 473
|
90
....*....|....*...
gi 13929190 103 PGAY-----PSAPGAYPA 115
Cdd:PHA03247 474 LDALrerrpPEPPGADLA 491
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
17-141 |
1.83e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 39.42 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 17 PNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQA-PPSAYPgptgpsAYPGPTAPGAYPGPTAPGAFPGQPGG 95
Cdd:PRK14086 100 PHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPtARPAYP------AYQQRPEPGAWPRAADDYGWQQQRLG 173
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 13929190 96 ---PGAYPSAPGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMPR 141
Cdd:PRK14086 174 fppRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPR 222
|
|
| hnRNP-L_PTB |
TIGR01649 |
hnRNP-L/PTB/hephaestus splicing factor family; Included in this family of heterogeneous ... |
45-148 |
2.17e-03 |
|
hnRNP-L/PTB/hephaestus splicing factor family; Included in this family of heterogeneous ribonucleoproteins are PTB (polypyrimidine tract binding protein) and hnRNP-L. These proteins contain four RNA recognition motifs (rrm: pfam00067).
Pssm-ID: 273733 [Multi-domain] Cd Length: 481 Bit Score: 39.03 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 45 PGQAPPGGYP--GQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAP 122
Cdd:TIGR01649 194 PGRRDPGLDQthRQRQPALLGQHPSSYGHDGYSSHGGPLAPLAGGDRMGPPHGPPSRYRPAYEAAPLAPAISSYGPAGGG 273
|
90 100
....*....|....*....|....*.
gi 13929190 123 TGPLTVPYDMPlPGGVMPRMLITIIG 148
Cdd:TIGR01649 274 PGSVLMVSGLH-QEKVNCDRLFNLFC 298
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
23-141 |
2.18e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 39.54 E-value: 2.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 23 PGAWGNQPGAGGYPGASYPGAYPGQAPPGGY---PGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAF--PGQPGGPG 97
Cdd:PHA03247 2786 PAVASLSESRESLPSPWDPADPPAAVLAPAAalpPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSvaPGGDVRRR 2865
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 13929190 98 AYPSAPGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMPR 141
Cdd:PHA03247 2866 PPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPP 2909
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
48-136 |
2.45e-03 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 38.83 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 48 APPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGqpggPGAYPSAPGAYPSAPGAypATGPFGAPTGPLT 127
Cdd:NF041121 19 AAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPL----PAPYPGSLAPPPPPPPG--PAGAAPGAALPVR 92
|
....*....
gi 13929190 128 VPYDMPLPG 136
Cdd:NF041121 93 VPAPPALPN 101
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
29-142 |
2.49e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 38.98 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 29 QPGAGGYPGASYPGAYPGQA-PPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTA-------PGAFPGQPGGPGAYP 100
Cdd:pfam03154 246 HPPLQPMTQPPPPSQVSPQPlPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQssqsqvpPGPSPAAPGQSQQRI 325
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 13929190 101 SAPGAYPSA-PGAYPATGPFgaPTGPLTVPYDMPLPGGVMPRM 142
Cdd:pfam03154 326 HTPPSQSQLqSQQPPREQPL--PPAPLSMPHIKPPPTTPIPQL 366
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
10-141 |
2.77e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 38.70 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 10 ALAGSGNPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGP----TAPGAYPGPTA 85
Cdd:PRK12323 432 ALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPppweELPPEFASPAP 511
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 13929190 86 PGAFPGQPGGPGAYPSAPG-AYPSAPGAYPATGPFGAPTGPLTVPYDmPLPGGVMPR 141
Cdd:PRK12323 512 AQPDAAPAGWVAESIPDPAtADPDDAFETLAPAPAAAPAPRAAAATE-PVVAPRPPR 567
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
30-133 |
3.30e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 38.61 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 30 PGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGP--TAPGAYPGPTAPGAFPGQPGGPGAYPSAPGAYP 107
Cdd:PHA03307 73 PGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPppTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
|
90 100
....*....|....*....|....*..
gi 13929190 108 SAPGAYPATGPFGAPTGP-LTVPYDMP 133
Cdd:PHA03307 153 PAAGASPAAVASDAASSRqAALPLSSP 179
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
41-137 |
4.19e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 38.51 E-value: 4.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 41 PGAYPGQAPPGGYPGQAPPSAYPGPT-GPSAYPGPTAPGAYPgPTA---PGAFPGQPGGPGAYPSAPGAYPSAPG-AYPA 115
Cdd:PHA03378 669 IGHIPYQPSPTGANTMLPIQWAPGTMqPPPRAPTPMRPPAAP-PGRaqrPAAATGRARPPAAAPGRARPPAAAPGrARPP 747
|
90 100
....*....|....*....|..
gi 13929190 116 TGPFGAPTGPLTVPYDMPLPGG 137
Cdd:PHA03378 748 AAAPGRARPPAAAPGRARPPAA 769
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
17-142 |
6.27e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 37.88 E-value: 6.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 17 PNPRGWPGAWGNQPGAGGYPGASYPGAYPG-------QAPPGGYPGQAP---PSAYPGPT---------GPSAYPGPTAP 77
Cdd:PRK14086 131 PGLPRQDQLPTARPAYPAYQQRPEPGAWPRaaddygwQQQRLGFPPRAPyasPASYAPEQerdrepydaGRPEYDQRRRD 210
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 13929190 78 GAYPGP--TAPGAF----PGQPGGPGAYPSAPGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLPGGVMPRM 142
Cdd:PRK14086 211 YDHPRPdwDRPRRDrtdrPEPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGEPTARL 281
|
|
| Glutenin_hmw |
pfam03157 |
High molecular weight glutenin subunit; Members of this family include high molecular weight ... |
24-125 |
6.37e-03 |
|
High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.
Pssm-ID: 367362 [Multi-domain] Cd Length: 786 Bit Score: 37.62 E-value: 6.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 24 GAWGNQPGAGGYPGASYPGAYPGQAPPGGYP------GQAPPSAYPGPT---GPSAYPGPTAPGAYPGPTAPGAFPGQPG 94
Cdd:pfam03157 326 GRQGQQPGQGQQGQQPAQGQQPGQGQPGYYPtspqqpGQGQPGYYPTSQqqpQQGQQPEQGQQGQQQGQGQQGQQPGQGQ 405
|
90 100 110
....*....|....*....|....*....|.
gi 13929190 95 GPGAypSAPGAYPSAPGAYPATGPFGAPTGP 125
Cdd:pfam03157 406 QPGQ--GQPGYYPTSPQQSGQGQPGYYPTSP 434
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
29-135 |
7.77e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 37.55 E-value: 7.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 29 QPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPG------PTAPGAFPGQPGGPGAYPSA 102
Cdd:PRK12323 367 QSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAaaparrSPAPEALAAARQASARGPGG 446
|
90 100 110
....*....|....*....|....*....|...
gi 13929190 103 PGAYPSAPGAYPATGPFGAPTGPLTVPYDMPLP 135
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAA 479
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
10-111 |
7.93e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 37.35 E-value: 7.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 10 ALAGSGNPNPRGWPGAwgNQPGAGGYPGASYPGAYPGQA-PPGGYPGQA-PPSAYPGPTGPSAYP-GPTAPGAYPgPTAP 86
Cdd:PHA03378 718 AAATGRARPPAAAPGR--ARPPAAAPGRARPPAAAPGRArPPAAAPGRArPPAAAPGAPTPQPPPqAPPAPQQRP-RGAP 794
|
90 100
....*....|....*....|....*
gi 13929190 87 GAFPGQPGGPGAYPSAPGAYPSAPG 111
Cdd:PHA03378 795 TPQPPPQAGPTSMQLMPRAAPGQQG 819
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
16-94 |
9.37e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 37.18 E-value: 9.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13929190 16 NPNPRGWPGAWGNQPGAGGYPGASYPGAYPGQAPPGGYPGQAPPSAYPGPTG-PSAYPGPTAPGAYPGPTAPGAFPGQPG 94
Cdd:PRK12270 37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAaAAAAAAPAAPPAAAAAAAPAAAAVEDE 116
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
43-118 |
9.78e-03 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 36.83 E-value: 9.78e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 13929190 43 AYPGQAPPGGYPGQAPPSAYPGPTGPSAYPGPTAPGAYPGPTAPGAfPGQPGGPGAYPSAPGAYPSAPGAYPATGP 118
Cdd:pfam07174 39 ADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNAPNAPPP-PADPNAPPPPPADPNAPPPPAVDPNAPEP 113
|
|
| |
