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Conserved domains on  [gi|1418586016|ref|YP_009494829|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Bathyraja meridionalis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 1.09e-78

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 231.18  E-value: 1.09e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGWG-WFVGDEINGLEMIRGDFSGVALLYSYGGSLLMLSGWMLLLALFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGsWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1418586016 160 LTRGISWGTLRTV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 1.09e-78

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 231.18  E-value: 1.09e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGWG-WFVGDEINGLEMIRGDFSGVALLYSYGGSLLMLSGWMLLLALFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGsWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1418586016 160 LTRGISWGTLRTV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 9.92e-12

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 59.44  E-value: 9.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  17 VAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALV-AEPYPESWGDWSVFVYVMFYV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLlAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1418586016  96 MCLMYInkyFVGDWGWGWFVGDEINGLEMIRGDFSGVALLYSYGGsLLMLSGWMLLLALFVVLEL 160
Cdd:pfam00499  81 LLLALL---LLVLLSASLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 1.09e-78

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 231.18  E-value: 1.09e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGWG-WFVGDEINGLEMIRGDFSGVALLYSYGGSLLMLSGWMLLLALFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGsWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1418586016 160 LTRGISWGTLRTV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 7.49e-62

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 188.52  E-value: 7.49e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGWGWFVGDEINGLEMIRGDFSGVALLYSYGGSLLMLSGWMLLLALFVVLEL 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                         170
                  ....*....|..
gi 1418586016 161 TRGISWGTLRTV 172
Cdd:MTH00065  161 TRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.01e-49

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 157.99  E-value: 1.01e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGWGWFVGDEIN--GLEMIRGDFSGVALLYSYGGSLLMLSGWMLLLALFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDsgGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1418586016 159 ELTRGISWGTLRTV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-163 6.46e-41

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 135.70  E-value: 6.46e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGD-WSVFVYVMFYVMCLMYINKYFVGD---------WGWGWFVGDEINGLEMIRGDFSGVALLYSYGGSLLMLSGWML 150
Cdd:MTH00109   82 TWVSnKVVLGALLLGLLMELLLVLYVLKDdevevvfnfNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 1418586016 151 LLALFVVLELTRG 163
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 9.13e-35

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 119.71  E-value: 9.13e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGW-GWFVGDEINGLEMirgdfSGVALLYSYGGSLLMLSGWMLLLALFVVLE 159
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMlSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 1418586016 160 LTRGISWGTLRTV 172
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-170 9.89e-19

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 78.02  E-value: 9.89e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSfimGLVAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00045    2 VFYLFLILMLF---GSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGWGWFVGDEInglemirgDFSGVALLYSYGGSLLMLSGWMLLLALFVVLEL 160
Cdd:MTH00045   79 VSNLGEVLVLSLLLSLWVFISFDNFLELSNNNWSLVSLS--------DLVGSSELYNSGGLYLLLGGFILLVALVVALVI 150

                         170
                  ....*....|
gi 1418586016 161 TRGISWGTLR 170
Cdd:MTH00045  151 SFGHEYSSLR 160
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 9.92e-12

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 59.44  E-value: 9.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016  17 VAVASNPSPYYAALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALV-AEPYPESWGDWSVFVYVMFYV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLlAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1418586016  96 MCLMYInkyFVGDWGWGWFVGDEINGLEMIRGDFSGVALLYSYGGsLLMLSGWMLLLALFVVLEL 160
Cdd:pfam00499  81 LLLALL---LLVLLSASLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-158 2.28e-05

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 42.57  E-value: 2.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418586016   1 MTYLMLIMMLSFIMGLVAVASNPSPYyaALGLVISAGVGCGLLVSSGSSFLSLVLFLIYLGGMLVVFAYTAALVAEPYPE 80
Cdd:MTH00152    1 MSLMILLSVCFSLFLLLPLSKQPLSL--GLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFG 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1418586016  81 SWGDWSVFVYVMFYVMCLMYINKYFVGDWGWGWFVGdeinglemirgdFSGVALLYSYGGSLLMLSGWMLLLALFVVL 158
Cdd:MTH00152   79 SNFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSSL------------FDGSSGSLSFGGGLYSSSGWSIFVFLAVLL 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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