|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
42-1025 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 977.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 42 VVKGVVKDSNGEPLLGVNVLVKGTTIGAVTDIDGNFSFEAPAGCTLVISYIGFESQEVKVKGNAPLNIILKEDSEALDEV 121
Cdd:TIGR04056 2 TVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDEV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 122 VVVGYGVQKKSDVTGALSSVKGDDLTKLSISRTDQALQGQMAGVMVQNSVAAPGESPNIIIRGGNSLKGENAPLVVIDGV 201
Cdd:TIGR04056 82 VVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVIDGV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 202 -LGGDLSLIDPNDITSIEVLKDASSTSIYGSRGANGVIMVTTKRGQTGKPTVSYSGYVSLSQVSKKMDMLNGQELYGLLK 280
Cdd:TIGR04056 162 pRDNGLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFSTPTRLPEMLNAYEYAELYN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 281 EAQEKYPT------TALKIPEWI---DPNNLNNTDWQGEVF-RTAPITGHSLSVSGGTETTRYSLSGNYLMHQGIVKNSD 350
Cdd:TIGR04056 242 EALLNRGSsppdiyTDEEIEAYRnglDPDLYPNTDWQDEIFkRTAFNQRHNLSVSGGTEKARYYVSLGYYNEEGILKNSD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 351 FNRAGIRANIEQKLGKKVTVGAlinasrsSSSNASVNQMNGSDGGGVTFSAL-----GFGPLVPVYKEDGSLSGPLKDGA 425
Cdd:TIGR04056 322 YKRYNFRANIDAKLTKTLKLSL-------NVSGSLSKYNNPGGSTSNIWGALmlfprGTPYSTPPVYSDGYYPAYNSGNT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 426 QMNNPVALINDQVVDKFRNYFQGTAFLEWEILNGLKFKTAWTYTYSDRKQRQFTSGE---NLLSYKGQGYAYMNDQETTN 502
Cdd:TIGR04056 395 SLQNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPyyyNATGGANNGYYSESNSRSRN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 503 WLGENTLTYSKTFNKdHSLNVVAGFTAEASDYFNNNSSGKGFDIESlgywnmglANSSLLSVASGGNHSAIASWLGRVNY 582
Cdd:TIGR04056 475 YYLEATLNYNRTFGK-HNVSALLGYSQQENKSSSYGGLLDDLPSLD--------AGTSDASVSGSDSEYRLQSLFGRATY 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 583 AYKGKYLASVSFRADGSSKFAKNNKWGYFPSAALGWRISEEDFMKDI-SWIQNLKLRASYGETGSQAIT---AYQSLASF 658
Cdd:TIGR04056 546 SYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEKFMKKLkKWLSFLKLRASYGIVGNDNIGdryPYLSLYNL 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 659 STTSYVL---NGSSAVALVPGRVPNPDLKWETTKQTDIGIDLSVLGGRISLVADYYYKKTVDLHYDKILPYYTGYSSQTQ 735
Cdd:TIGR04056 626 GDGGYNFgtnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYA 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 736 NIGSKSNKGWEFSLNTQNLVG-DFKWSTSLNIALNREKVLDLGDDEYFYTNGSggalgagfnetGIVKVGEPLGNFYGYV 814
Cdd:TIGR04056 706 NIGKVKNKGVELSLNYRNKIGkDFSWSVRGNFTYNKNKILELDEGAYLPVKYP-----------YISKEGGPIGQIYGYI 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 815 FDGIYQNEAEAKAlGLTKDDVGSVKFKDLNGDNKITTEDRTIIGN-ANPDFIFGIGNDFSYKNFDLSFMFQGTYGNDVYN 893
Cdd:TIGR04056 775 ADGLFKDDDSPKQ-TFGNVRPGDIKYKDVNGDGKIDDDDRVPIGYsNTPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFN 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 894 LlkvTFSELPSNSNNTGNAF-AFVKDSWRGEGTSNTQQAFNKGVGPS------SSRFVEDGSYIRLKNLTFGYTLPKSVT 966
Cdd:TIGR04056 854 D---GRGFYPFNGGDWGNVLkIVADNRWTPENPNADYPRLSYGDSNNsnnyqaSTRWLEDGSYLRLKNLTLGYTLPKKWL 930
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 1469545500 967 SKWGISNLRFYLSGQNLFTITGYSGYDPEVSsrtgnynlGFDGGSYPATRSYTFGLNLT 1025
Cdd:TIGR04056 931 KKIGISNLRVYFSGQNLFTFSKYKGWDPELQ--------GNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
118-785 |
3.23e-61 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 221.24 E-value: 3.23e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 118 LDEVVVVGYG-VQKKSDVTGALSSVKGDDLTKLSISRTDQALQgQMAGVMVQNSVaapGESPNIIIRGGNSlkGENAPLV 196
Cdd:COG1629 1 LEEVVVTATRtDESLQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSVTSAG---GGAGQISIRGFGG--GGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 197 VIDGV-------LGGDLSLIDPNDITSIEVLKDASSTsIYGSRGANGVIMVTTKRGQTGKptvsySGYVSLSQVSkkmdm 269
Cdd:COG1629 75 LVDGVplndpsgGDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGK-----GGEVSASYGS----- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 270 lngqelYGLLKeaqekypttalkipewidpnnlnntdwqgevfrtapitgHSLSVSGGTETTRYSLSGNYLMHQGIVKNS 349
Cdd:COG1629 144 ------YGTYR---------------------------------------ASLSLSGGNGKLAYRLSASYRDSDGYRDNS 178
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 350 DFNRAGIRANIEQKLGKKVTVGALINAsrssssnasvNQMNGSDGGGVTFSALGfgplvpvykedgslsgPLKDGAQMNN 429
Cdd:COG1629 179 DSDRYNLRAKLGYQLGDDTRLTLSASY----------SDSDQDSPGYLTLAALR----------------PRGAMDDGTN 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 430 PVALINDQvvdkfRNYFQGTAFLEWEILN-GLKFKTAWTYTYSDRKQRQFTSGenllSYKGQGYAYMNDQETTNWLGENT 508
Cdd:COG1629 233 PYSNDTDD-----NTRDRYSLSLEYEHLGdGLKLSASAYYRYDDTDLDSDFTP----TPADGGTLEQTDFDNRTYGLELR 303
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 509 LTYSKTFNKDHSLnvVAGFtaeasDYFNNNSSGKGFDIESLGYWNMGLANSSLLSVasggnHSAIASWLGRVNYAYKGKY 588
Cdd:COG1629 304 LTYDLGFGGKHTL--LVGL-----DYQRQDLDGSGYPLDLGSGSLPTLTSGADDDG-----TTTSLALYAQDTYKLTDKL 371
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 589 LASVSFRADGSSKFAKN------------NKWGYFPSAALGWRISEedfmkdiswiqNLKLRASYGEtGSQAITAYQSLA 656
Cdd:COG1629 372 TLTAGLRYDYVSYDVDDtvtgtdsasgsrSYSAFSPSLGLTYQLSP-----------NLSLYASYSR-GFRAPTFGELYA 439
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 657 SFSTtsyvlngssavalvPGRVPNPDLKWETTKQTDIGIDLSVLGGRISLVADYYYKKTVDLHYDKILPYYTGYSSQTQN 736
Cdd:COG1629 440 NGTD--------------PYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYYTN 505
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 1469545500 737 IGSKSNKGWEFSLNTQNLVGdfkWSTSLNIALNREKVLDLGDDEYFYTN 785
Cdd:COG1629 506 AGKARSYGVELELSYQLTPG---LSLNASYSYTDAKFDDDTDGSADLDG 551
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
43-123 |
4.11e-23 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 94.20 E-value: 4.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 43 VKGVVKD-SNGEPLLGVNVLVKGTTIGAVTDIDGNFSFEA-PAG-CTLVISYIGFESQEVKVK----GNAPLNIILKEDS 115
Cdd:pfam13715 1 ISGTVVDeNTGEPLPGATVYVKGTTKGTVTDADGNFELKNlPAGtYTLVVSFVGYKTQEKKVTvsndNTLDVNFLLKEDA 80
|
....*...
gi 1469545500 116 EALDEVVV 123
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
139-779 |
1.72e-14 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 77.88 E-value: 1.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 139 SSVKGDDLTKLSISRTDQALQgQMAGVMVQNSvaAPGESPNIIIRGgnsLKGENApLVVIDGV--------LGGDLSLID 210
Cdd:cd01347 3 SVITAEDIEKQPATSLADLLR-RIPGVSVTRG--GGGGGSTISIRG---FGPDRT-LVLVDGLplassnygRGVDLNTIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 211 PNDITSIEVLKDASStSIYGSRGANGVIMVTTKRGQTGkptvsYSGYVSLSQVSKKmdmlngqelygllkeaqekyptta 290
Cdd:cd01347 76 PELIERVEVLKGPSS-ALYGSGAIGGVVNIITKRPTDE-----FGGSVTAGYGSDN------------------------ 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 291 lkipewidPNNLNNTDWqgevfrtapitGHSLSVSGGtETTRYSLSGNY------LMHQGIVKNSDFNRAGIRANIEQKL 364
Cdd:cd01347 126 --------SGSSGGGGF-----------DVSGALADD-GAFGARLYGAYrdgdgtIDGDGQADDSDEERYNVAGKLDWRP 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 365 GKKVTVGAlinasrssssnasvnqmngsDGGGVTFSALGFGPLVPVYKEDGSLSGPLKDGAQmnnpvaliNDQVVDKFRN 444
Cdd:cd01347 186 DDDTRLTL--------------------DAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTN--------GDRDWDYRDR 237
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 445 YFQgTAFLEWE---ILNGLKFKTAWTYTYSDRKQRQFTS--GENLLSYKGQGYAYMNDQETTNWLGENTLTYS-KTFNKD 518
Cdd:cd01347 238 YRK-RASLGLEhdlNDTGWTLRANLSYSYTDNDGDPLILngGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAPfGTGPVA 316
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 519 HSLnvVAGFTAeasDYFNNNSSGKGF----DIESLGYWNMGLAnssllsvasggnhsaiaswlGRVnYAYKGKYLASVSF 594
Cdd:cd01347 317 HTL--TLGVEY---RREELDEKQTALyaqdTIELTDDLTLTLG--------------------LRY-DHYDQDSKDTIAG 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 595 RADGSSKFAKNNkwgyfPSAALGWRISEedfmkdiswiqNLKLRASYGEtGSQAITAYQSLASFSTTSYVLNGssavalv 674
Cdd:cd01347 371 GTTAKKSYSHWS-----PSLGLVYKLTD-----------GLSLYASYSQ-GFRAPSLGELYGGGSHGGTAAVG------- 426
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 675 pgrvpNPDLKWETTKQTDIGIDLSvLGGRISLVADYYYKKTVDLHYDKILPYYTGYSSQTQNIGSKSNKGWEFSLNTQnL 754
Cdd:cd01347 427 -----NPNLKPEKSKQYELGLKYD-PGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYD-L 499
|
650 660
....*....|....*....|....*
gi 1469545500 755 VGDFKWSTSLNIALNREKVLDLGDD 779
Cdd:cd01347 500 TDGLGLTGSYTYTDTEVKRTDGATT 524
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
42-1025 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 977.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 42 VVKGVVKDSNGEPLLGVNVLVKGTTIGAVTDIDGNFSFEAPAGCTLVISYIGFESQEVKVKGNAPLNIILKEDSEALDEV 121
Cdd:TIGR04056 2 TVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDEV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 122 VVVGYGVQKKSDVTGALSSVKGDDLTKLSISRTDQALQGQMAGVMVQNSVAAPGESPNIIIRGGNSLKGENAPLVVIDGV 201
Cdd:TIGR04056 82 VVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVIDGV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 202 -LGGDLSLIDPNDITSIEVLKDASSTSIYGSRGANGVIMVTTKRGQTGKPTVSYSGYVSLSQVSKKMDMLNGQELYGLLK 280
Cdd:TIGR04056 162 pRDNGLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFSTPTRLPEMLNAYEYAELYN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 281 EAQEKYPT------TALKIPEWI---DPNNLNNTDWQGEVF-RTAPITGHSLSVSGGTETTRYSLSGNYLMHQGIVKNSD 350
Cdd:TIGR04056 242 EALLNRGSsppdiyTDEEIEAYRnglDPDLYPNTDWQDEIFkRTAFNQRHNLSVSGGTEKARYYVSLGYYNEEGILKNSD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 351 FNRAGIRANIEQKLGKKVTVGAlinasrsSSSNASVNQMNGSDGGGVTFSAL-----GFGPLVPVYKEDGSLSGPLKDGA 425
Cdd:TIGR04056 322 YKRYNFRANIDAKLTKTLKLSL-------NVSGSLSKYNNPGGSTSNIWGALmlfprGTPYSTPPVYSDGYYPAYNSGNT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 426 QMNNPVALINDQVVDKFRNYFQGTAFLEWEILNGLKFKTAWTYTYSDRKQRQFTSGE---NLLSYKGQGYAYMNDQETTN 502
Cdd:TIGR04056 395 SLQNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPyyyNATGGANNGYYSESNSRSRN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 503 WLGENTLTYSKTFNKdHSLNVVAGFTAEASDYFNNNSSGKGFDIESlgywnmglANSSLLSVASGGNHSAIASWLGRVNY 582
Cdd:TIGR04056 475 YYLEATLNYNRTFGK-HNVSALLGYSQQENKSSSYGGLLDDLPSLD--------AGTSDASVSGSDSEYRLQSLFGRATY 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 583 AYKGKYLASVSFRADGSSKFAKNNKWGYFPSAALGWRISEEDFMKDI-SWIQNLKLRASYGETGSQAIT---AYQSLASF 658
Cdd:TIGR04056 546 SYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEKFMKKLkKWLSFLKLRASYGIVGNDNIGdryPYLSLYNL 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 659 STTSYVL---NGSSAVALVPGRVPNPDLKWETTKQTDIGIDLSVLGGRISLVADYYYKKTVDLHYDKILPYYTGYSSQTQ 735
Cdd:TIGR04056 626 GDGGYNFgtnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYA 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 736 NIGSKSNKGWEFSLNTQNLVG-DFKWSTSLNIALNREKVLDLGDDEYFYTNGSggalgagfnetGIVKVGEPLGNFYGYV 814
Cdd:TIGR04056 706 NIGKVKNKGVELSLNYRNKIGkDFSWSVRGNFTYNKNKILELDEGAYLPVKYP-----------YISKEGGPIGQIYGYI 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 815 FDGIYQNEAEAKAlGLTKDDVGSVKFKDLNGDNKITTEDRTIIGN-ANPDFIFGIGNDFSYKNFDLSFMFQGTYGNDVYN 893
Cdd:TIGR04056 775 ADGLFKDDDSPKQ-TFGNVRPGDIKYKDVNGDGKIDDDDRVPIGYsNTPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFN 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 894 LlkvTFSELPSNSNNTGNAF-AFVKDSWRGEGTSNTQQAFNKGVGPS------SSRFVEDGSYIRLKNLTFGYTLPKSVT 966
Cdd:TIGR04056 854 D---GRGFYPFNGGDWGNVLkIVADNRWTPENPNADYPRLSYGDSNNsnnyqaSTRWLEDGSYLRLKNLTLGYTLPKKWL 930
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 1469545500 967 SKWGISNLRFYLSGQNLFTITGYSGYDPEVSsrtgnynlGFDGGSYPATRSYTFGLNLT 1025
Cdd:TIGR04056 931 KKIGISNLRVYFSGQNLFTFSKYKGWDPELQ--------GNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
118-785 |
3.23e-61 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 221.24 E-value: 3.23e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 118 LDEVVVVGYG-VQKKSDVTGALSSVKGDDLTKLSISRTDQALQgQMAGVMVQNSVaapGESPNIIIRGGNSlkGENAPLV 196
Cdd:COG1629 1 LEEVVVTATRtDESLQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSVTSAG---GGAGQISIRGFGG--GGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 197 VIDGV-------LGGDLSLIDPNDITSIEVLKDASSTsIYGSRGANGVIMVTTKRGQTGKptvsySGYVSLSQVSkkmdm 269
Cdd:COG1629 75 LVDGVplndpsgGDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGK-----GGEVSASYGS----- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 270 lngqelYGLLKeaqekypttalkipewidpnnlnntdwqgevfrtapitgHSLSVSGGTETTRYSLSGNYLMHQGIVKNS 349
Cdd:COG1629 144 ------YGTYR---------------------------------------ASLSLSGGNGKLAYRLSASYRDSDGYRDNS 178
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 350 DFNRAGIRANIEQKLGKKVTVGALINAsrssssnasvNQMNGSDGGGVTFSALGfgplvpvykedgslsgPLKDGAQMNN 429
Cdd:COG1629 179 DSDRYNLRAKLGYQLGDDTRLTLSASY----------SDSDQDSPGYLTLAALR----------------PRGAMDDGTN 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 430 PVALINDQvvdkfRNYFQGTAFLEWEILN-GLKFKTAWTYTYSDRKQRQFTSGenllSYKGQGYAYMNDQETTNWLGENT 508
Cdd:COG1629 233 PYSNDTDD-----NTRDRYSLSLEYEHLGdGLKLSASAYYRYDDTDLDSDFTP----TPADGGTLEQTDFDNRTYGLELR 303
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 509 LTYSKTFNKDHSLnvVAGFtaeasDYFNNNSSGKGFDIESLGYWNMGLANSSLLSVasggnHSAIASWLGRVNYAYKGKY 588
Cdd:COG1629 304 LTYDLGFGGKHTL--LVGL-----DYQRQDLDGSGYPLDLGSGSLPTLTSGADDDG-----TTTSLALYAQDTYKLTDKL 371
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 589 LASVSFRADGSSKFAKN------------NKWGYFPSAALGWRISEedfmkdiswiqNLKLRASYGEtGSQAITAYQSLA 656
Cdd:COG1629 372 TLTAGLRYDYVSYDVDDtvtgtdsasgsrSYSAFSPSLGLTYQLSP-----------NLSLYASYSR-GFRAPTFGELYA 439
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 657 SFSTtsyvlngssavalvPGRVPNPDLKWETTKQTDIGIDLSVLGGRISLVADYYYKKTVDLHYDKILPYYTGYSSQTQN 736
Cdd:COG1629 440 NGTD--------------PYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYYTN 505
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 1469545500 737 IGSKSNKGWEFSLNTQNLVGdfkWSTSLNIALNREKVLDLGDDEYFYTN 785
Cdd:COG1629 506 AGKARSYGVELELSYQLTPG---LSLNASYSYTDAKFDDDTDGSADLDG 551
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
105-783 |
4.05e-41 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 161.18 E-value: 4.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 105 APLNIILKEDSEALDEVVVVGYGV-QKKSDVTGALSSVKGDDLTKLSISRTDQALQgQMAGVMVQNSVAAPGESpNIIIR 183
Cdd:COG4771 14 AQAADALAEDATELEEVVVTATRTeQSLSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVTRSGGRGGSS-GISIR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 184 GGNSlkgeNAPLVVIDGV--------LGGDLSLIDPNDITSIEVLKDASSTsIYGSRGANGVIMVTTKRGQTGKptvsyS 255
Cdd:COG4771 92 GLGG----DRVLVLIDGVpvnnpalgGGGDLSYIPPDDIERIEVIRGPASA-LYGSDAIGGVINIITKKPTDEL-----E 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 256 GYVSLSqvskkmdmlngqelYGllkeaqekypttalkipewidpnNLNNTDWQGevfrtapitghSLSVSGGTETTRYSL 335
Cdd:COG4771 162 GSVSLG--------------YG-----------------------SNGNGTYSG-----------SLSLGGPGDKLSFLL 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 336 SGNYLMHQGIVKNSDFNRAGIRANIEQKLGKKVTVgalinasrssssnasvnqmNGSDGGGVTFSALGfgplvpvYKEDG 415
Cdd:COG4771 194 SGSYRDRDGYLDYRNGGFVGNSGYERYNLNAKLGY-------------------RLSDNHRLSLSGGY-------SRQDR 247
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 416 SLSGPLKDGAQMNNPVALINDQvvdkfrNYFQGTAFLEWEILNGLKFKTAWTYTYSDRKQRQFTSGenllsykgQGYAYM 495
Cdd:COG4771 248 DGGPPTLGDTEISSDNAGDRDT------TTDRGNYSLRYNGDLGDNLDLSLYYSRTDRDSTNGSLG--------GSTGSF 313
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 496 NDQETTNWLGEntLTYSKTFNKDHSLnvVAGFtaeasDYFNNNSSGKGFDIESLGYWNmglanssllsvasggNHSAIAS 575
Cdd:COG4771 314 SDSDDTTYGLE--LDLTYPLGGNHTL--TLGA-----EYRYDDLDSSSFLGGADASRD---------------TYGLFAQ 369
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 576 WlgrvNYAYKGKYLASVSFRADGSSKFAKNNKWGYFPSAALGWRISEedfmkdiswiqNLKLRASYGeTGSQAITAYQsl 655
Cdd:COG4771 370 D----EWKLTDKLTLTAGLRYDYYSTFGASNYTAFSPRLGLRYDLSD-----------NLTLRASYG-RGFRAPSLAE-- 431
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 656 asfsttsyvLNGSSAVALVPGRVPNPDLKWETTKQTDIGIDLSVLGGRISLVADYYYKKTVDLHYDKILPYYTGYSSQTQ 735
Cdd:COG4771 432 ---------LYGSGTGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQYE 502
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 1469545500 736 NIGSKSNKGWEFSLNTQnlVGDfKWSTSLNIALNREKVLDLGDDEYFY 783
Cdd:COG4771 503 NVGKARTYGLELELKYR--LGK-GLTLTASYTYLDSKIDDGDTGEPLP 547
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
121-327 |
3.35e-31 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 123.83 E-value: 3.35e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 121 VVVVGYGV-QKKSDVTGALSSVKGDDLTKLSISRTDQALQgQMAGVMVQNSvAAPGESPNIIIRGGNSlkgeNAPLVVID 199
Cdd:COG4206 1 VVVTATRLeQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQVSSS-GGPGSAASISIRGLGS----NQTLVLID 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 200 GV------LGG-DLSLIDPNDITSIEVLKDASStSIYGSRGANGVIMVTTKRGQTG-KPTVSYS-GYVSLSQVSKKMdML 270
Cdd:COG4206 75 GVplndpsLGGvDLSLIPPDDIERIEVLKGAAS-ALYGSDAIGGVINITTKKGKKGfKGSVSASyGSFGTRRLSASL-SG 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1469545500 271 NGQELYGLLKEAQEKYPTTALKIPEWIDPNNLNNTDWQGEVfRTAPITGHSLSVSGG 327
Cdd:COG4206 153 GAGKFSYSLSASYRRSDGYRYNDPDLRNNDGYENTSLNARL-GYKLGDNGSLSLSGG 208
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
43-123 |
4.11e-23 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 94.20 E-value: 4.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 43 VKGVVKD-SNGEPLLGVNVLVKGTTIGAVTDIDGNFSFEA-PAG-CTLVISYIGFESQEVKVK----GNAPLNIILKEDS 115
Cdd:pfam13715 1 ISGTVVDeNTGEPLPGATVYVKGTTKGTVTDADGNFELKNlPAGtYTLVVSFVGYKTQEKKVTvsndNTLDVNFLLKEDA 80
|
....*...
gi 1469545500 116 EALDEVVV 123
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
130-237 |
9.23e-18 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 79.62 E-value: 9.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 130 KKSDVTGALSSVKGDDLTKLSISRTDQALQGqMAGVMVQNSvaAPGESPNIIIRGGNSlkgeNAPLVVIDGV-------L 202
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSVSSG--GGGGGSSISIRGFGS----NRVLVLVDGVplnsgggG 73
|
90 100 110
....*....|....*....|....*....|....*
gi 1469545500 203 GGDLSLIDPNDITSIEVLKDASSTsIYGSRGANGV 237
Cdd:pfam07715 74 SVDLNSIDPEDIERVEVLKGPASA-LYGSGAIGGV 107
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
139-779 |
1.72e-14 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 77.88 E-value: 1.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 139 SSVKGDDLTKLSISRTDQALQgQMAGVMVQNSvaAPGESPNIIIRGgnsLKGENApLVVIDGV--------LGGDLSLID 210
Cdd:cd01347 3 SVITAEDIEKQPATSLADLLR-RIPGVSVTRG--GGGGGSTISIRG---FGPDRT-LVLVDGLplassnygRGVDLNTIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 211 PNDITSIEVLKDASStSIYGSRGANGVIMVTTKRGQTGkptvsYSGYVSLSQVSKKmdmlngqelygllkeaqekyptta 290
Cdd:cd01347 76 PELIERVEVLKGPSS-ALYGSGAIGGVVNIITKRPTDE-----FGGSVTAGYGSDN------------------------ 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 291 lkipewidPNNLNNTDWqgevfrtapitGHSLSVSGGtETTRYSLSGNY------LMHQGIVKNSDFNRAGIRANIEQKL 364
Cdd:cd01347 126 --------SGSSGGGGF-----------DVSGALADD-GAFGARLYGAYrdgdgtIDGDGQADDSDEERYNVAGKLDWRP 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 365 GKKVTVGAlinasrssssnasvnqmngsDGGGVTFSALGFGPLVPVYKEDGSLSGPLKDGAQmnnpvaliNDQVVDKFRN 444
Cdd:cd01347 186 DDDTRLTL--------------------DAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTN--------GDRDWDYRDR 237
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 445 YFQgTAFLEWE---ILNGLKFKTAWTYTYSDRKQRQFTS--GENLLSYKGQGYAYMNDQETTNWLGENTLTYS-KTFNKD 518
Cdd:cd01347 238 YRK-RASLGLEhdlNDTGWTLRANLSYSYTDNDGDPLILngGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAPfGTGPVA 316
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 519 HSLnvVAGFTAeasDYFNNNSSGKGF----DIESLGYWNMGLAnssllsvasggnhsaiaswlGRVnYAYKGKYLASVSF 594
Cdd:cd01347 317 HTL--TLGVEY---RREELDEKQTALyaqdTIELTDDLTLTLG--------------------LRY-DHYDQDSKDTIAG 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 595 RADGSSKFAKNNkwgyfPSAALGWRISEedfmkdiswiqNLKLRASYGEtGSQAITAYQSLASFSTTSYVLNGssavalv 674
Cdd:cd01347 371 GTTAKKSYSHWS-----PSLGLVYKLTD-----------GLSLYASYSQ-GFRAPSLGELYGGGSHGGTAAVG------- 426
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 675 pgrvpNPDLKWETTKQTDIGIDLSvLGGRISLVADYYYKKTVDLHYDKILPYYTGYSSQTQNIGSKSNKGWEFSLNTQnL 754
Cdd:cd01347 427 -----NPNLKPEKSKQYELGLKYD-PGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYD-L 499
|
650 660
....*....|....*....|....*
gi 1469545500 755 VGDFKWSTSLNIALNREKVLDLGDD 779
Cdd:cd01347 500 TDGLGLTGSYTYTDTEVKRTDGATT 524
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
213-243 |
3.30e-12 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 61.44 E-value: 3.30e-12
10 20 30
....*....|....*....|....*....|.
gi 1469545500 213 DITSIEVLKDASSTSIYGSRGANGVIMVTTK 243
Cdd:TIGR04057 1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
390-752 |
5.71e-12 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 69.41 E-value: 5.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 390 NGSDGGGVTFSALGFGPLVPVYKEDGSLSGPLKDGAQMNNPVALINDQVVDKFRNYFQGTAFLEWEILNGLKFKTAWTYT 469
Cdd:pfam00593 7 DLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 470 YSDRKQRQFTSGENLlsykgQGYAYMNDQETTNWLGENTLTYSKTFNKDHSLNVVAGFTAEASDYFNNNSSGKGfdieSL 549
Cdd:pfam00593 87 YSSLDGDYTSNSSGL-----SGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYD----PY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 550 GYWNMGLANSSLLSVASGGNHsaiaswlGRVNYAYKGKYLASVSFRADGSSKFAKN----------NKWGYFPSAALGWR 619
Cdd:pfam00593 158 DPANPSSSSYSDTTTDSYGLY-------LQDNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrSYSAFSPRLGLVYK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 620 ISEedfmkdiswiqNLKLRASYgetgSQAITAYQSLASFSTTSYVLNGSsavalvpGRVPNPDLKWETTKQTDIGIDLsv 699
Cdd:pfam00593 231 PTD-----------NLSLYASY----SRGFRAPSLGELYGSGSGGGGGA-------VAGGNPDLKPETSDNYELGLKY-- 286
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1469545500 700 LGGRISLVADYYYKKTVDLHY-DKILPYYTGYSSQTQNIGSKSNKGWEFSLNTQ 752
Cdd:pfam00593 287 DDGRLSLSLALFYIDIKNLITsDPDGPGLGGTVYTYTNVGKARIRGVELELSGR 340
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
43-111 |
8.73e-10 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 56.13 E-value: 8.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 43 VKGVVKDSNGEPLLGVNVLVK----GTTIGAVTDIDGNFSFEA-PAG-CTLVISYIGFESQE-----VKVKGNAPLNIIL 111
Cdd:pfam13620 2 ISGTVTDPSGAPVPGATVTVTntdtGTVRTTTTDADGRYRFPGlPPGtYTVTVSAPGFKTATrtgvtVTAGQTTTLDVTL 81
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
118-765 |
1.54e-08 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 58.56 E-value: 1.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 118 LDEVVVVGY-GVQKKSDVTGALSSVKGDDLTKLSISRTDQALQGQMaGVMVQNSVAAPGESPNIiiRGgnslKGENAPLV 196
Cdd:TIGR01785 1 LDTVTVTATrTRQVLSEAPASVSVISGEQIESKQANNLADALNTVP-GVDVTGGGRPPGQSINI--RG----LQDNRVLV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 197 VIDGVLGGD--------LSLIDPNDITSIEVLKDASSTsIYGSRGANGVIMVTTKrgqtgkptvsysgyvslsqvsKKMD 268
Cdd:TIGR01785 74 VVDGARQNYqrggahngSLFVDPELLKRIEIVKGPSSS-LYGSGALGGVVAFRTK---------------------DAAD 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 269 ML-NGQELYGLLKeaqekypTTAlkipewidpnNLNNTDWQGEVFRTAPITGHSLSVSGGTETTryslSGNYlmhqgivK 347
Cdd:TIGR01785 132 LLrPGQLFGGLAK-------LSY----------GSNNNSFGGSVAVAGRLDDNLDALVAATYRD----GGNY-------R 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 348 NSDFNRAGIRANIEQKLGKKVTVgalinasrssssnasvnQMNGSdgggvtfSALGFGplvpVYKEDGSLSGPLKDGAQM 427
Cdd:TIGR01785 184 NGNKEEATNSAYVQKNLLAKLGW-----------------QLDDA-------QRLEFS----YFTTEGSLDEAQNSGPGT 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 428 NNPVALINDQVVDKFRNY---FQGTAFLEWEILNGLKFKTAWTYTYSDrkqrqftsgeNLLSYKGQGYAYMNDQETTNWL 504
Cdd:TIGR01785 236 EYVLGSSSTLLASSTRDRsatLTYNWTPEDNPWLDATASLYYNRTEND----------NDRSARGVGREEGYQYTTYGAT 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 505 GENTltysKTFNKDHSLNVVAGFtaeasDYFNNNSSGKGFDIESLGYWNMGLANssllsvasgGNHSAIASWLGRVNYAY 584
Cdd:TIGR01785 306 LQNT----SRFDVASWSTLTYGV-----DWMKDKRRTESFDPNSVTTIVPNPPS---------AKEYFFGLFLQDNIPLL 367
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 585 KGKYLASVSFRADGSSKFAKNNKWGYF---------PSAALGWRiseedfmkdisWIQNLKLRASYGEtGSQAITAYQSl 655
Cdd:TIGR01785 368 DDRLTLSAGLRYDHYKLSPKTTADTEAvdrsysrwsPSLGLSYK-----------PVDWLTLYASYSQ-GFRAPSIDEL- 434
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 656 asfsttsYVLNGSSAVALVPGRVPNPDLKWETTKQTDIGIDLS---VLGGRISL---VADYYYKktVDLHYDKILPYYTG 729
Cdd:TIGR01785 435 -------YGTGDHPGTPGGYTFAPNPNLKPETSKTWELGANLSfdnLLLDNDQLqfkVAYFYND--VKDFIDLTIGVTDN 505
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 1469545500 730 YS------SQTQNIGSKSNKGWEFSLNTQnlVGDFKWSTSLN 765
Cdd:TIGR01785 506 VTagmnniTQYVNIDGARIRGIEASASYD--AGLWATGLSYG 545
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
113-247 |
4.87e-07 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 53.78 E-value: 4.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 113 EDSEALDEVVVVGYGVQKKS--DVTGALSSVKGDDLTKLSISRTDQALQgQMAGVMVQNSvAAPGESPNIIIRGGNSLKG 190
Cdd:COG4772 18 EAATTLETVVVTGSRAAEARlkDVPGSVSVVDREELENQAATSLREVLR-RVPGVNVQEE-DGFGLRPNIGIRGLGPRRS 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1469545500 191 ENApLVVIDGVL---------GGDLSLiDPNDITSIEVLKDASSTsIYGSRGANGVIMVTTKRGQT 247
Cdd:COG4772 96 RGI-TLLEDGIPiapapygdpAAYYFP-DLERMERIEVLRGAAAL-RYGPQTVGGAINFVTRTIPT 158
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
133-246 |
4.21e-05 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 47.41 E-value: 4.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 133 DVTGALSSVKGDDLTKLSISRTDQALQgQMAGVMVQNSVAApGESPNIIIRGGNSLkgENAPLVVIDGV---LGGDLSLI 209
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAGSLSEALQ-RVPGVVVGGSGGT-TQFGNITIRGFGLE--VDIDNVYLDGVpllSRGNLAIV 76
|
90 100 110
....*....|....*....|....*....|....*..
gi 1469545500 210 DPNDITSIEVLKDASSTsIYGSRGANGVIMVTTKRGQ 246
Cdd:TIGR01783 77 DPAMVERVEVLRGPASL-LYGGSAPGGVINIVTKRPQ 112
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
86-752 |
5.48e-05 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 47.20 E-value: 5.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 86 TLVISYIGFESQEVKVKGNAPLniilKEDSEALDEVVVVGYGVQKKSDVTGALSSVKGDDLTKL----SIS--------- 152
Cdd:COG4773 4 LLAGSGLAAAAAGALAQAAAAA----AAEATTLPEVTVTGTAEGTGGYTAKSSSTATKLDTPLRetpqSVSvvtrqlied 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 153 ----RTDQALQgQMAGVMVQNSVAapGESPNIIIRGGNslkgenAPLVVIDGVLGGDL--SLIDPNDITSIEVLKDASST 226
Cdd:COG4773 80 qgatTLDDALR-NVPGVTVSSYDG--GGRDSFSIRGFS------IDNYLRDGLPLGGFggGQPDTANLERVEVLKGPAGL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 227 sIYGSRGANGVIMVTTKRgqtgkPTVSYSGYVSLSqvskkmdmlngqelYGllkeaqekypttalkipewidpnnlNNTD 306
Cdd:COG4773 151 -LYGAGSPGGLVNLVTKR-----PTAEPQGEVSLS--------------AG-------------------------SWDT 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 307 WQGEVFRTAPITghslsvsgGTETTRYSLSGNYLMHQGIVKNSDFNRAGIRANIEQKLGKK--VTVGALINAsrssssna 384
Cdd:COG4773 186 YRATADVGGPLN--------EDGTLRYRLNAAYEDGDSFRDGVDNRRTLIAPSLDWDLTDDttLTLGAEYQD-------- 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 385 svNQMNGSDGggvTFSALGFGPLVPVYKedgSLSGPlkdgaqmnnpvaliNDQVVDKFRNYFqgtAFLEWEILNGLKFKT 464
Cdd:COG4773 250 --DDSTGDRG---FLPLDGTLLDLPRST---NLGEP--------------WDYYDTETTTLF---AELEHRFNDDWSLRA 304
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 465 AWTYTYSDRKQRQFTSGENLLSYKG--QGYAYMNDQETTNWLGENTLTYS-KTFNKDHslNVVAGFTAEASDYFNNNSSG 541
Cdd:COG4773 305 NARYSDSDRDGRSAYAYGAPDAATGtlTRYASARDGDSRSDSLDANLNGKfETGGLEH--TLLVGADYSRYDSDSDSATA 382
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 542 KGFDIESLGYWNMGLANSSLLSVASGGNHSAI-----ASWLGRV---------NYAYKGKYLASVSFRADGSSKFAknnk 607
Cdd:COG4773 383 GTINIYNPVYGNLPEPDFDASDTDTTTRQTGLyaqdqISLTDRLslllggrydWYETDSTNRLGGSTTSYDDSAFT---- 458
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 608 wgyfPSAALGWRISEedfmkdiswiqNLKLRASYGEtgsqaitayqslaSFSTTSYVLNGssavalvpGRVPNPdlkwET 687
Cdd:COG4773 459 ----PRAGLVYDLTP-----------GLSLYASYSE-------------SFEPQSGADNN--------GNPLDP----ET 498
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1469545500 688 TKQTDIGIDLSVLGGRISLVADYYykktvDLHYDKIL---PYYTGYSSQtqnIGSKSNKGWEFSLNTQ 752
Cdd:COG4773 499 GKQYEAGVKGELFDGRLNATLAVF-----DITQKNVAttdPDNPNFYVQ---VGEVRSRGVELELSGE 558
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
167-781 |
6.43e-05 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 46.79 E-value: 6.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 167 VQNSVAAPGESPNIIIRGGNSlkgenAPLVVIDGVLGGDLSLIDPNDITSIEVLKDASSTsIYGSRGANGVIMVTTKRgq 246
Cdd:COG4774 39 VTFGAGEGGNGDSFSIRGFSA-----SGDIYVDGLRDPGQYRRDTFNLERVEVLKGPASV-LYGRGSPGGVINLVTKR-- 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 247 tgkPTVSYSGYVSLSqvskkmdmlngqelYGllkeaqekypttalkipewidpnnlnnTDWQGEVfrtapitghSLSVSG 326
Cdd:COG4774 111 ---PTDEPFTEVTLT--------------YG---------------------------SDGQRRA---------TLDVNG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 327 G-TETTRYSLSGNYLMHQGIVKNSDFNRAGIRANIEQKLGKKVTVGALInasrssssnASVNQMNGSDGGgvtfsalgfg 405
Cdd:COG4774 138 PlGDDLAYRLNGMYRDSDSYRDGVDNDRWGIAPSLTWRLGDRTRLTLDY---------EYQDDDRTPDYG---------- 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 406 plVPVYKEDGSLSGPLKdgAQMNNPVALINDQVvdkfrnyFQGTAFLEWEILNGLKFKTAWTYTYSDRKQRQFTSGENLL 485
Cdd:COG4774 199 --VPAVANGRPVDVDRS--TFYGQPDDYSDSET-------DSATLRLEHDFNDNWTLRNALRYSDYDRDYRNTYPTGGNA 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 486 SYKGQGYAYMNDQETTNWLGENTLTYS-KTFNKDHslNVVAGFTAEASDYFNNNSSGKG----FDIES--LGYWNMGLAN 558
Cdd:COG4774 268 TGTVTRSAYRRDQDNDTLSNQTDLTGKfDTGGVKH--TLLAGVEYSREDSDNARYSGGGtaptVNLYNpvYGAPVTGPTL 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 559 SSLLSVASGGNHSAIAS--------WL----GRVNYaYKGKYLASVSFRADGSSKFAKNNkwgyfPSAALGWRISEedfm 626
Cdd:COG4774 346 GGADNDSRTDTTGLYLQdtisltdrWSllagLRYDR-FDTDYTDRTTGATTSSYDDSAFS-----PRAGLVYKPTP---- 415
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1469545500 627 kdiswiqNLKLRASYGEtgsqaitayqslaSFSTTSYVLNGSSAvalvpgrvpNPDLKWETTKQTDIGIDLSVLGGRISL 706
Cdd:COG4774 416 -------NLSLYASYST-------------SFNPGGGAPSLSNA---------GQALDPEKSRQYEVGVKWDLLDGRLSL 466
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1469545500 707 -VADYYYKKTVDLHYDkilPYYTGYSSQTqniGSKSNKGWEFSLNTQnlVGDfKWSTSLNIALNREKVLDLGDDEY 781
Cdd:COG4774 467 tAALFRIEKTNVRTTD---PANPGVYVQT---GEQRSRGVELEATGE--LTP-GWSVLAGYTYLDAEITKSANAAN 533
|
|
| |
