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Conserved domains on  [gi|148667211|gb|EDK99627|]
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RAD52 homolog (S. cerevisiae), isoform CRA_g [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rad52_Rad22 super family cl42453
Rad52/22 family double-strand break repair protein; The DNA single-strand annealing proteins ...
 39-64 3.94e-10

Rad52/22 family double-strand break repair protein; The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family includes proteins related to Rad52. These proteins contain two helix-hairpin-helix motifs.


The actual alignment was detected with superfamily member TIGR00607:

Pssm-ID: 455798  Cd Length: 161  Bit Score: 52.50  E-value: 3.94e-10
                          10        20
                  ....*....|....*....|....*.
gi 148667211   39 AIQKALRQRLGPEYISSRMAGGGQKI 64
Cdd:TIGR00607   1 AIQKALRQKLGPEYISSRSGGGGQKV 26
 
Name Accession Description Interval E-value
rad52 TIGR00607
recombination protein rad52; All proteins in this family for which functions are known are ...
 39-64 3.94e-10

recombination protein rad52; All proteins in this family for which functions are known are involved in recombination and recombination repair. Their exact biochemical activity is not yet known.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129695  Cd Length: 161  Bit Score: 52.50  E-value: 3.94e-10
                          10        20
                  ....*....|....*....|....*.
gi 148667211   39 AIQKALRQRLGPEYISSRMAGGGQKI 64
Cdd:TIGR00607   1 AIQKALRQKLGPEYISSRSGGGGQKV 26
Rad52_Rad22 pfam04098
Rad52/22 family double-strand break repair protein; The DNA single-strand annealing proteins ...
 36-64 5.40e-06

Rad52/22 family double-strand break repair protein; The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family includes proteins related to Rad52. These proteins contain two helix-hairpin-helix motifs.


Pssm-ID: 367812  Cd Length: 140  Bit Score: 41.16  E-value: 5.40e-06
                          10        20
                  ....*....|....*....|....*....
gi 148667211   36 EYQAIQKALRQRLGPEYISSRMAGGGQKI 64
Cdd:pfam04098   1 EIGTLQAKLEKPLGPEYISWRPGPGGQKV 29
 
Name Accession Description Interval E-value
rad52 TIGR00607
recombination protein rad52; All proteins in this family for which functions are known are ...
 39-64 3.94e-10

recombination protein rad52; All proteins in this family for which functions are known are involved in recombination and recombination repair. Their exact biochemical activity is not yet known.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129695  Cd Length: 161  Bit Score: 52.50  E-value: 3.94e-10
                          10        20
                  ....*....|....*....|....*.
gi 148667211   39 AIQKALRQRLGPEYISSRMAGGGQKI 64
Cdd:TIGR00607   1 AIQKALRQKLGPEYISSRSGGGGQKV 26
Rad52_Rad22 pfam04098
Rad52/22 family double-strand break repair protein; The DNA single-strand annealing proteins ...
 36-64 5.40e-06

Rad52/22 family double-strand break repair protein; The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family includes proteins related to Rad52. These proteins contain two helix-hairpin-helix motifs.


Pssm-ID: 367812  Cd Length: 140  Bit Score: 41.16  E-value: 5.40e-06
                          10        20
                  ....*....|....*....|....*....
gi 148667211   36 EYQAIQKALRQRLGPEYISSRMAGGGQKI 64
Cdd:pfam04098   1 EIGTLQAKLEKPLGPEYISWRPGPGGQKV 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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