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Conserved domains on  [gi|148686559|gb|EDL18506|]
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small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta, isoform CRA_b, partial [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
50-158 1.23e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.16  E-value: 1.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100
                 ....*....|....*....|....*....
gi 148686559 130 AVTSYQKALDLDPENDSYKSNLKIAEQKL 158
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLEL 123
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
50-158 1.23e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.16  E-value: 1.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100
                 ....*....|....*....|....*....
gi 148686559 130 AVTSYQKALDLDPENDSYKSNLKIAEQKL 158
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLEL 123
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 43-195 1.56e-21

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 91.77  E-value: 1.56e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 122
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 148686559 123 AMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSptgtGLSFDMASLINNPAFITMAASLMQNPQV 195
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEK----DLVQPVPSDLPSSVTAPPVEEADATPVV 150
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 43-161 4.46e-13

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 68.09  E-value: 4.46e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNnAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 122
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPD-PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYD 205

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 148686559  123 AMNKFEEAVTSYQKALDLDPENDSYKSNL------KIAEQKLREV 161
Cdd:TIGR00990 206 GLGKYADALLDLTASCIIDGFRNEQSAQAverllkKFAESKAKEI 250
TPR_1 pfam00515
Tetratricopeptide repeat;
111-144 3.16e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 45.49  E-value: 3.16e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 148686559  111 SKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEN 144
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 111-144 1.09e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.97  E-value: 1.09e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 148686559   111 SKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEN 144
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 86-145 1.95e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.62  E-value: 1.95e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148686559  86 AQSKL--SHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEND 145
Cdd:cd24142    7 AEELLdqGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGG 68
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
50-158 1.23e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.16  E-value: 1.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100
                 ....*....|....*....|....*....
gi 148686559 130 AVTSYQKALDLDPENDSYKSNLKIAEQKL 158
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLEL 123
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
50-160 1.55e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 95.07  E-value: 1.55e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                         90       100       110
                 ....*....|....*....|....*....|.
gi 148686559 130 AVTSYQKALDLDPENDSYKSNLKIAEQKLRE 160
Cdd:COG0457  129 AIEAYERALELDPDDADALYNLGIALEKLGR 159
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 43-151 2.38e-23

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 98.14  E-value: 2.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 122
Cdd:COG3914  112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                         90       100
                 ....*....|....*....|....*....
gi 148686559 123 AMNKFEEAVTSYQKALDLDPENDSYKSNL 151
Cdd:COG3914  192 DLGRLEEAIAAYRRALELDPDNADAHSNL 220
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 43-195 1.56e-21

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 91.77  E-value: 1.56e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 122
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 148686559 123 AMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSptgtGLSFDMASLINNPAFITMAASLMQNPQV 195
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEK----DLVQPVPSDLPSSVTAPPVEEADATPVV 150
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
27-159 4.01e-21

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 88.05  E-value: 4.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  27 NDIRPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAI 106
Cdd:COG4785   57 ALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALEL 136

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 148686559 107 DSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLR 159
Cdd:COG4785  137 DPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLD 189
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 43-151 5.71e-21

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.21  E-value: 5.71e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 122
Cdd:COG3914   78 AALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALR 157

                         90       100
                 ....*....|....*....|....*....
gi 148686559 123 AMNKFEEAVTSYQKALDLDPENDSYKSNL 151
Cdd:COG3914  158 RLGRLEEAIAALRRALELDPDNAEALNNL 186
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 50-145 1.03e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 81.98  E-value: 1.03e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                         90
                 ....*....|....*.
gi 148686559 130 AVTSYQKALDLDPEND 145
Cdd:COG4235  104 AIAAWQKLLALLPADA 119
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 41-160 1.12e-19

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 82.16  E-value: 1.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  41 GKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLA 120
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 148686559 121 LTAMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 160
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGR 121
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
70-158 4.10e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 83.13  E-value: 4.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  70 IELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPENDSYKS 149
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80


                 ....*....
gi 148686559 150 NLKIAEQKL 158
Cdd:COG0457   81 NLGLALQAL 89
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
50-160 4.62e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.44  E-value: 4.62e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                         90       100       110
                 ....*....|....*....|....*....|.
gi 148686559 130 AVTSYQKALDLDPENDSYKSNLKIAEQKLRE 160
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAAA 193
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-158 1.32e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 79.77  E-value: 1.32e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG2956  117 AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                         90       100
                 ....*....|....*....|....*....
gi 148686559 130 AVTSYQKALDLDPENDSYKSNLKIAEQKL 158
Cdd:COG2956  197 AIAALERALEQDPDYLPALPRLAELYEKL 225
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 53-142 1.89e-17

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 76.54  E-value: 1.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  53 HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVT 132
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                         90
                 ....*....|
gi 148686559 133 SYQKALDLDP 142
Cdd:COG5010  144 ALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
53-143 2.37e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 72.13  E-value: 2.37e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  53 HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKdCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVT 132
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|.
gi 148686559 133 SYQKALDLDPE 143
Cdd:COG3063   81 YLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 50-144 1.60e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 70.99  E-value: 1.60e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG4783   45 GEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE 124

                         90
                 ....*....|....*
gi 148686559 130 AVTSYQKALDLDPEN 144
Cdd:COG4783  125 AIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-157 4.38e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.76  E-value: 4.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                         90       100
                 ....*....|....*....|....*...
gi 148686559 130 AVTSYQKALDLDPENDSYKSNLKIAEQK 157
Cdd:COG2956  231 ALELLRKALELDPSDDLLLALADLLERK 258
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 61-151 5.98e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 66.57  E-value: 5.98e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  61 AAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDL 140
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90
                 ....*....|.
gi 148686559 141 DPENDSYKSNL 151
Cdd:COG4235   81 DPDNPEALYLL 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 49-157 3.66e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.06  E-value: 3.66e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  49 EGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFE 128
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90       100       110
                 ....*....|....*....|....*....|
gi 148686559 129 EAVTSYQKALDLDPENDSYKSNL-KIAEQK 157
Cdd:COG2956   94 RAEELLEKLLELDPDDAEALRLLaEIYEQE 123
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 43-161 4.46e-13

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 68.09  E-value: 4.46e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNnAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 122
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPD-PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYD 205

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 148686559  123 AMNKFEEAVTSYQKALDLDPENDSYKSNL------KIAEQKLREV 161
Cdd:TIGR00990 206 GLGKYADALLDLTASCIIDGFRNEQSAQAverllkKFAESKAKEI 250
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-144 1.82e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 1.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG2956   83 AQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDE 162

                         90
                 ....*....|....*
gi 148686559 130 AVTSYQKALDLDPEN 144
Cdd:COG2956  163 AIEALEKALKLDPDC 177
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 43-162 2.01e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.09  E-value: 2.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALT 122
Cdd:COG3914   44 ALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLL 123

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 148686559 123 AMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVS 162
Cdd:COG3914  124 ALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 50-130 3.21e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 59.62  E-value: 3.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEV 232


                 .
gi 148686559 130 A 130
Cdd:COG3914  233 Y 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-157 3.48e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 3.48e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG2956   49 GNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEK 128

                         90       100
                 ....*....|....*....|....*....
gi 148686559 130 AVTSYQKALDLDPENDSYKSNL-KIAEQK 157
Cdd:COG2956  129 AIEVLERLLKLGPENAHAYCELaELYLEQ 157
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 53-160 6.87e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.12  E-value: 6.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  53 HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVT 132
Cdd:COG5010   30 ALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKE 109

                         90       100
                 ....*....|....*....|....*...
gi 148686559 133 SYQKALDLDPENDSYKSNLKIAEQKLRE 160
Cdd:COG5010  110 YYEKALALSPDNPNAYSNLAALLLSLGQ 137
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
86-160 9.24e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.32  E-value: 9.24e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 148686559  86 AQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVtSYQKALDLDPENDSYKSNLKIAEQKLRE 160
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGD 74
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
50-141 3.67e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 3.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:COG0457  117 GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVL 196

                         90
                 ....*....|..
gi 148686559 130 AVTSYQKALDLD 141
Cdd:COG0457  197 LALLLALEQALR 208
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 67-144 4.33e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 53.45  E-value: 4.33e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148686559   67 TQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEN 144
Cdd:TIGR00990 355 SKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDF 432
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 38-144 1.62e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 1.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   38 EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRM 117
Cdd:TIGR02917 188 ADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLK 267

                          90       100
                  ....*....|....*....|....*..
gi 148686559  118 GLALTAMNKFEEAVTSYQKALDLDPEN 144
Cdd:TIGR02917 268 ALVDFQKKNYEDARETLQDALKSAPEY 294
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 52-161 2.18e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 48.06  E-value: 2.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  52 NHMKEENYAAAVDCYTQAIELDPN-----NAVYYcnRAAAQSKLSHYTDAIKDCEKAIAI---DSKYSKAYGRMGLALTA 123
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRYPNsplapDALYW--LGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLE 79

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 148686559 124 MNKFEEAVTSYQKALDLDPENDSYksnlKIAEQKLREV 161
Cdd:COG1729   80 LGDYDKARATLEELIKKYPDSEAA----KEARARLARL 113
TPR_1 pfam00515
Tetratricopeptide repeat;
111-144 3.16e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 45.49  E-value: 3.16e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 148686559  111 SKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEN 144
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 111-144 1.09e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.97  E-value: 1.09e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 148686559   111 SKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEN 144
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 86-145 1.95e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.62  E-value: 1.95e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148686559  86 AQSKL--SHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEND 145
Cdd:cd24142    7 AEELLdqGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGG 68
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 50-107 2.39e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.11  E-value: 2.39e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148686559  50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAID 107
Cdd:COG5010   95 ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-163 3.61e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 3.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   50 GNNHMKEENYAAAVDCYTQAIELDPNNAvyYCNRAAAQSKLSH--YTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKF 127
Cdd:TIGR02917 132 GLAYLGLGQLELAQKSYEQALAIDPRSL--YAKLGLAQLALAEnrFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNI 209

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 148686559  128 EEAVTSYQKALDLDPENDSY---KSNLKIAEQKLREVSS 163
Cdd:TIGR02917 210 ELALAAYRKAIALRPNNIAVllaLATILIEAGEFEEAEK 248
TPR_11 pfam13414
TPR repeat;
50-90 6.39e-06

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 42.07  E-value: 6.39e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 148686559   50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKL 90
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TPR_11 pfam13414
TPR repeat;
118-158 8.52e-06

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 41.69  E-value: 8.52e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 148686559  118 GLALTAMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 158
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 49-143 2.46e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.97  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   49 EGNNHMKEENYaaavdcYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFE 128
Cdd:TIGR00990 377 ELGDPDKAEED------FDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIA 450

                          90
                  ....*....|....*
gi 148686559  129 EAVTSYQKALDLDPE 143
Cdd:TIGR00990 451 SSMATFRRCKKNFPE 465
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 50-145 2.46e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.97  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:TIGR00990 406 AQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDE 485

                          90
                  ....*....|....*.
gi 148686559  130 AVTSYQKALDLDPEND 145
Cdd:TIGR00990 486 AIEKFDTAIELEKETK 501
TPR_1 pfam00515
Tetratricopeptide repeat;
43-76 5.62e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.33  E-value: 5.62e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 148686559   43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNN 76
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_17 pfam13431
Tetratricopeptide repeat;
65-98 6.23e-05

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 39.06  E-value: 6.23e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 148686559   65 CYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIK 98
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_1 pfam00515
Tetratricopeptide repeat;
77-110 6.65e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.94  E-value: 6.65e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 148686559   77 AVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKY 110
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 43-76 7.65e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 7.65e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 148686559    43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNN 76
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 112-143 1.59e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.89  E-value: 1.59e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 148686559  112 KAYGRMGLALTAMNKFEEAVTSYQKALDLDPE 143
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_12 pfam13424
Tetratricopeptide repeat;
80-143 1.59e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 1.59e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148686559   80 YCNRAAAQSKLSHYTDAIKDCEKAIAIDSKY--------SKAYGRMGLALTAMNKFEEAVTSYQKALDLDPE 143
Cdd:pfam13424   6 LNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhpltATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 77-110 2.63e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 2.63e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 148686559    77 AVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKY 110
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_8 pfam13181
Tetratricopeptide repeat;
112-143 3.23e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.99  E-value: 3.23e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 148686559  112 KAYGRMGLALTAMNKFEEAVTSYQKALDLDPE 143
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 43-75 3.57e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.12  E-value: 3.57e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 148686559   43 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPN 75
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 49-158 3.65e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 3.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   49 EGNNHMKEENYAAAVDCYTQAIELDPN--NAVYYcnrAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNK 126
Cdd:TIGR02917 709 EGDLYLRQKDYPAAIQAYRKALKRAPSsqNAIKL---HRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKD 785

                          90       100       110
                  ....*....|....*....|....*....|..
gi 148686559  127 FEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 158
Cdd:TIGR02917 786 YDKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL 817
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-135 4.14e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEE 129
Cdd:TIGR02917 608 GRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTES 687


                  ....*.
gi 148686559  130 AVTSYQ 135
Cdd:TIGR02917 688 AKKIAK 693
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 44-140 5.80e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 5.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  44 DQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAID-----SKYskaygrMG 118
Cdd:cd24142    1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDpdggyEKY------LY 74

                         90       100
                 ....*....|....*....|....
gi 148686559 119 LA--LTAmnkfEEAVTSYQKALDL 140
Cdd:cd24142   75 LGqlSGG----EEALQYYEKGIEI 94
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 33-112 6.39e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 40.16  E-value: 6.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  33 SNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAI---DSK 109
Cdd:PLN03088  26 TQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALEKGASLapgDSR 105


                 ...
gi 148686559 110 YSK 112
Cdd:PLN03088 106 FTK 108
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 59-151 9.63e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 9.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  59 YAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKAL 138
Cdd:COG5010    2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                         90
                 ....*....|...
gi 148686559 139 DLDPENDSYKSNL 151
Cdd:COG5010   82 QLDPNNPELYYNL 94
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 54-159 1.04e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   54 MKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTS 133
Cdd:TIGR02917 340 LRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIAD 419

                          90       100
                  ....*....|....*....|....*.
gi 148686559  134 YQKALDLDPenDSYKSNLKIAEQKLR 159
Cdd:TIGR02917 420 LETAAQLDP--ELGRADLLLILSYLR 443
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 33-146 2.01e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 39.20  E-value: 2.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   33 SNSVPEDVGKAdqLKDEGNNHMK---EENYAAAVDCYTQAI---ELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAI 106
Cdd:TIGR00990 283 SNELDEETGNG--QLQLGLKSPEskaDESYEEAARAFEKALdlgKLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIEL 360

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 148686559  107 DSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPENDS 146
Cdd:TIGR00990 361 DPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPD 400
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 54-153 2.10e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 38.30  E-value: 2.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559  54 MKEENYAAAVDCYTQAIELDPNNAVyycnRAAAQSKLSHYTDAIKDCEKAIA-IDSKYSKAYG-----RMGLALTAMNKF 127
Cdd:COG2976  101 VDAGDLDKAAAQLQWVLDNAKDPAL----KALARLRLARVLLAQKKYDEALAtLDAVKPEAFAalyaeLRGDILLAQGDK 176

                         90       100
                 ....*....|....*....|....*.
gi 148686559 128 EEAVTSYQKALDLDPENDSYKSNLKI 153
Cdd:COG2976  177 AEARAAYQKALAALPEDAPLRQLLQM 202
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 96-149 2.62e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 38.91  E-value: 2.62e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 148686559   96 AIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPenDSYKS 149
Cdd:PRK11447  288 AIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDP--HSSNR 339
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 74-145 4.26e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.14  E-value: 4.26e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148686559   74 PNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEND 145
Cdd:TIGR02917 598 PDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNT 669
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-157 4.66e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.14  E-value: 4.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148686559   50 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCnrAAAQSKLSH--YTDAIKDCEKAIAIDSKYSKA-------------- 113
Cdd:TIGR02917 370 GEAYLALGDFEKAAEYLAKATELDPENAAART--QLGISKLSQgdPSEAIADLETAAQLDPELGRAdlllilsylrsgqf 447

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 148686559  114 --------------------YGRMGLALTAMNKFEEAVTSYQKALDLDPENDSYKSNL-KIAEQK 157
Cdd:TIGR02917 448 dkalaaakklekkqpdnaslHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLaRIDIQE 512
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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