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Conserved domains on  [gi|148700440|gb|EDL32387|]
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ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1, isoform CRA_c [Mus musculus]

Protein Classification

ubiquinol-cytochrome c reductase iron-sulfur subunit( domain architecture ID 10131115)

ubiquinol-cytochrome c reductase iron-sulfur subunit is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rieske_cytochrome_bc1 cd03470
Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske ...
 12-135 1.52e-81

Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including uni- and multi-cellular eukaryotes, plants (in their mitochondria) and bacteria. The cytochrome bc(1) and b6f complexes are central components of the respiratory and photosynthetic electron transport chains, respectively, which carry out similar core electron and proton transfer steps. The bc(1) and b6f complexes share a common core structure of three catalytic subunits: cyt b, the Rieske ISP, and either a cyt c1 in the bc(1) complex or cyt f in the b6f complex, which are arranged in an integral membrane-bound dimeric complex. While the core of the b6f complex is similar to that of the bc(1) complex, the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


:

Pssm-ID: 239552  Cd Length: 126  Bit Score: 235.15  E-value: 1.52e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440  12 KIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDP--QHDLDRVKKPEWVILIGVCTHLGCVPIANA 89
Cdd:cd03470    1 PVEVDLSKIEEGQLITVEWRGKPVFIRRRTPEEIAEAKAVDLSLLDDPdpAANRVRSGKPEWLVVIGICTHLGCVPTYRA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 148700440  90 GDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVVVG 135
Cdd:cd03470   81 GDYGGFFCPCHGSHYDASGRIRKGPAPLNLEVPPYKFLSDTTIVIG 126
 
Name Accession Description Interval E-value
Rieske_cytochrome_bc1 cd03470
Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske ...
 12-135 1.52e-81

Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including uni- and multi-cellular eukaryotes, plants (in their mitochondria) and bacteria. The cytochrome bc(1) and b6f complexes are central components of the respiratory and photosynthetic electron transport chains, respectively, which carry out similar core electron and proton transfer steps. The bc(1) and b6f complexes share a common core structure of three catalytic subunits: cyt b, the Rieske ISP, and either a cyt c1 in the bc(1) complex or cyt f in the b6f complex, which are arranged in an integral membrane-bound dimeric complex. While the core of the b6f complex is similar to that of the bc(1) complex, the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


Pssm-ID: 239552  Cd Length: 126  Bit Score: 235.15  E-value: 1.52e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440  12 KIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDP--QHDLDRVKKPEWVILIGVCTHLGCVPIANA 89
Cdd:cd03470    1 PVEVDLSKIEEGQLITVEWRGKPVFIRRRTPEEIAEAKAVDLSLLDDPdpAANRVRSGKPEWLVVIGICTHLGCVPTYRA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 148700440  90 GDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVVVG 135
Cdd:cd03470   81 GDYGGFFCPCHGSHYDASGRIRKGPAPLNLEVPPYKFLSDTTIVIG 126
Rieske_proteo TIGR01416
ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the ...
 1-135 3.37e-64

ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the Proteobacterial and mitochondrial type of the Rieske [2Fe-2S] iron-sulfur as found in ubiquinol-cytochrome c reductase. The model excludes the Rieske iron-sulfur protein as found in the cytochrome b6-f complex of the Cyanobacteria and chloroplasts. Most members of this family have a recognizable twin-arginine translocation (tat) signal sequence (DeltaPh-dependent translocation in chloroplast) for transport across the membrane with the 2Fe-2S group already bound. These signal sequences include a motif resembling RRxFLK before the transmembrane helix. [Energy metabolism, Electron transport]


Pssm-ID: 273610 [Multi-domain]  Cd Length: 174  Bit Score: 192.98  E-value: 3.37e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440    1 MSASADVLAM-SKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDP-----QHDLDRVK---KPEW 71
Cdd:TIGR01416  29 MNPSASVKAAgAPTEVDVSKIQPGQQLTVEWRGKPVFIRRRTKKEIDELKALDLGALKDPnseaqQPDYARVKrsgKPEW 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 148700440   72 VILIGVCTHLGCVPI--ANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVVVG 135
Cdd:TIGR01416 109 LVVIGICTHLGCIPTygPEEGDKGGFFCPCHGSHYDTAGRVRKGPAPLNLPVPPYKFLSDTTILIG 174
QcrA/PetC COG0723
Rieske Fe-S protein [Energy production and conversion];
1-133 4.77e-38

Rieske Fe-S protein [Energy production and conversion];


Pssm-ID: 440487 [Multi-domain]  Cd Length: 118  Bit Score: 125.11  E-value: 4.77e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440   1 MSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHrtkkeidqeaavevsqlrdpqhdLDRVKKPEWVILIGVCTH 80
Cdd:COG0723    7 VSPSAKAKAGAPVEVDLSDLPPGEGKVVEWRGKPVFVVR-----------------------TPVRGDGEIVAVSAICTH 63

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 148700440  81 LGCVPIANaGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVV 133
Cdd:COG0723   64 LGCPVTWN-ADEGGFDCPCHGSRFDPDGRVLKGPAPRPLPVPPLEVDDDKLLI 115
PRK13474 PRK13474
cytochrome b6-f complex iron-sulfur subunit; Provisional
 77-134 3.77e-17

cytochrome b6-f complex iron-sulfur subunit; Provisional


Pssm-ID: 237392 [Multi-domain]  Cd Length: 178  Bit Score: 73.15  E-value: 3.77e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148700440  77 VCTHLGCVPIANAGDfGGYYCPCHGSHYDASGRIRKGPAPLNLEVpAYEFTSDDVVVV 134
Cdd:PRK13474 106 VCTHLGCVVPWNSGE-NKFQCPCHGSQYDATGKVVRGPAPLSLAL-VHVTVEDDKVLF 161
Rieske pfam00355
Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines ...
 65-121 2.36e-10

Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilizes the protein.


Pssm-ID: 425632 [Multi-domain]  Cd Length: 89  Bit Score: 53.51  E-value: 2.36e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 148700440   65 RVKKPEWVILIGVCTHLGCVPIANAGDFGGYY-CPCHGSHYDASGRIRKGPAPLNLEV 121
Cdd:pfam00355  30 RDEDGELYALEDRCPHRGAPLSEGKVNGGGRLeCPYHGWRFDGTGKVVKVPAPRPLKS 87
 
Name Accession Description Interval E-value
Rieske_cytochrome_bc1 cd03470
Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske ...
 12-135 1.52e-81

Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including uni- and multi-cellular eukaryotes, plants (in their mitochondria) and bacteria. The cytochrome bc(1) and b6f complexes are central components of the respiratory and photosynthetic electron transport chains, respectively, which carry out similar core electron and proton transfer steps. The bc(1) and b6f complexes share a common core structure of three catalytic subunits: cyt b, the Rieske ISP, and either a cyt c1 in the bc(1) complex or cyt f in the b6f complex, which are arranged in an integral membrane-bound dimeric complex. While the core of the b6f complex is similar to that of the bc(1) complex, the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


Pssm-ID: 239552  Cd Length: 126  Bit Score: 235.15  E-value: 1.52e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440  12 KIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDP--QHDLDRVKKPEWVILIGVCTHLGCVPIANA 89
Cdd:cd03470    1 PVEVDLSKIEEGQLITVEWRGKPVFIRRRTPEEIAEAKAVDLSLLDDPdpAANRVRSGKPEWLVVIGICTHLGCVPTYRA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 148700440  90 GDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVVVG 135
Cdd:cd03470   81 GDYGGFFCPCHGSHYDASGRIRKGPAPLNLEVPPYKFLSDTTIVIG 126
Rieske_proteo TIGR01416
ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the ...
 1-135 3.37e-64

ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the Proteobacterial and mitochondrial type of the Rieske [2Fe-2S] iron-sulfur as found in ubiquinol-cytochrome c reductase. The model excludes the Rieske iron-sulfur protein as found in the cytochrome b6-f complex of the Cyanobacteria and chloroplasts. Most members of this family have a recognizable twin-arginine translocation (tat) signal sequence (DeltaPh-dependent translocation in chloroplast) for transport across the membrane with the 2Fe-2S group already bound. These signal sequences include a motif resembling RRxFLK before the transmembrane helix. [Energy metabolism, Electron transport]


Pssm-ID: 273610 [Multi-domain]  Cd Length: 174  Bit Score: 192.98  E-value: 3.37e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440    1 MSASADVLAM-SKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDP-----QHDLDRVK---KPEW 71
Cdd:TIGR01416  29 MNPSASVKAAgAPTEVDVSKIQPGQQLTVEWRGKPVFIRRRTKKEIDELKALDLGALKDPnseaqQPDYARVKrsgKPEW 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 148700440   72 VILIGVCTHLGCVPI--ANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVVVG 135
Cdd:TIGR01416 109 LVVIGICTHLGCIPTygPEEGDKGGFFCPCHGSHYDTAGRVRKGPAPLNLPVPPYKFLSDTTILIG 174
QcrA/PetC COG0723
Rieske Fe-S protein [Energy production and conversion];
1-133 4.77e-38

Rieske Fe-S protein [Energy production and conversion];


Pssm-ID: 440487 [Multi-domain]  Cd Length: 118  Bit Score: 125.11  E-value: 4.77e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440   1 MSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHrtkkeidqeaavevsqlrdpqhdLDRVKKPEWVILIGVCTH 80
Cdd:COG0723    7 VSPSAKAKAGAPVEVDLSDLPPGEGKVVEWRGKPVFVVR-----------------------TPVRGDGEIVAVSAICTH 63

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 148700440  81 LGCVPIANaGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVV 133
Cdd:COG0723   64 LGCPVTWN-ADEGGFDCPCHGSRFDPDGRVLKGPAPRPLPVPPLEVDDDKLLI 115
PRK13474 PRK13474
cytochrome b6-f complex iron-sulfur subunit; Provisional
 77-134 3.77e-17

cytochrome b6-f complex iron-sulfur subunit; Provisional


Pssm-ID: 237392 [Multi-domain]  Cd Length: 178  Bit Score: 73.15  E-value: 3.77e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148700440  77 VCTHLGCVPIANAGDfGGYYCPCHGSHYDASGRIRKGPAPLNLEVpAYEFTSDDVVVV 134
Cdd:PRK13474 106 VCTHLGCVVPWNSGE-NKFQCPCHGSQYDATGKVVRGPAPLSLAL-VHVTVEDDKVLF 161
Rieske_cytochrome_b6f cd03471
Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske ...
 77-134 2.85e-16

Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The cytochrome b6f complex from Mastigocladus laminosus, a thermophilic cyanobacterium, contains four large subunits, including cytochrome f, cytochrome b6, the Rieske ISP, and subunit IV; as well as four small hydrophobic subunits, PetG, PetL, PetM, and PetN. Rieske ISP, one of the large subunits of the cytochrome bc-type complexes, is involved in respiratory and photosynthetic electron transfer. The core of the chloroplast b6f complex is similar to the analogous respiratory cytochrome bc(1) complex, but the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


Pssm-ID: 239553  Cd Length: 126  Bit Score: 69.70  E-value: 2.85e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148700440  77 VCTHLGCVPIANAGDfGGYYCPCHGSHYDASGRIRKGPAPLNLEVpAYEFTSDDVVVV 134
Cdd:cd03471   54 VCTHLGCVVPWNAAE-NKFKCPCHGSQYDATGKVVRGPAPLSLAL-VHATVDDDKVVL 109
Rieske cd03467
Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron ...
 16-133 1.47e-13

Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.


Pssm-ID: 239550 [Multi-domain]  Cd Length: 98  Bit Score: 62.12  E-value: 1.47e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440  16 KLSDIPEGKNMAFKWRGKPLFVRHRtkkeidqeaavevsqlrdpqhdldrvKKPEWVILIGVCTHLGCVPIANAGDFGGY 95
Cdd:cd03467    6 ALSELPPGGGRVVVVGGGPVVVVRR--------------------------EGGEVYALSNRCTHQGCPLSEGEGEDGCI 59

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 148700440  96 YCPCHGSHYD-ASGRIRKGPAPLNLEVPAYEFTSDDVVV 133
Cdd:cd03467   60 VCPCHGSRFDlRTGEVVSGPAPRPLPKYPVKVEGDGVVW 98
Rieske pfam00355
Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines ...
 65-121 2.36e-10

Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilizes the protein.


Pssm-ID: 425632 [Multi-domain]  Cd Length: 89  Bit Score: 53.51  E-value: 2.36e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 148700440   65 RVKKPEWVILIGVCTHLGCVPIANAGDFGGYY-CPCHGSHYDASGRIRKGPAPLNLEV 121
Cdd:pfam00355  30 RDEDGELYALEDRCPHRGAPLSEGKVNGGGRLeCPYHGWRFDGTGKVVKVPAPRPLKS 87
Rieske_YhfW_C cd03477
YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an ...
 77-121 3.29e-07

YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. It is commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. YhfW is found in bacteria, some eukaryotes and archaea.


Pssm-ID: 239559 [Multi-domain]  Cd Length: 91  Bit Score: 45.37  E-value: 3.29e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 148700440  77 VCTHLGCVPIANAGDfGGYYCPCHGSHYDASGRIRKGPAPLNLEV 121
Cdd:cd03477   39 TCTHLGCIVHWNDAE-KSWDCPCHGSRFSYDGEVIEGPAVSGLKP 82
NirD COG2146
Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase [Inorganic ion ...
 10-135 5.97e-07

Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase [Inorganic ion transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441749 [Multi-domain]  Cd Length: 103  Bit Score: 44.83  E-value: 5.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440  10 MSKIEI-KLSDIPEGKNMAFKWRGKPLFVrHRTKKEIdqeAAVEvsqlrdpqhdldrvkkpewviliGVCTHLGCvPIAn 88
Cdd:COG2146    1 MSEVKVcALDDLPEGGGVVVEVGGKQIAV-FRTDGEV---YAYD-----------------------NRCPHQGA-PLS- 51

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 148700440  89 AGDFGGYY--CPCHGSHYD-ASGRIRKGPAPLNLevPAYEFT-SDDVVVVG 135
Cdd:COG2146   52 EGIVDGGVvtCPLHGARFDlRTGECLGGPATEPL--KTYPVRvEDGDVYVD 100
Rieske_ArOX_small cd03476
Small subunit of Arsenite oxidase (ArOX) family, Rieske domain; ArOX is a molybdenum/iron ...
 76-135 6.60e-07

Small subunit of Arsenite oxidase (ArOX) family, Rieske domain; ArOX is a molybdenum/iron protein involved in the detoxification of arsenic, oxidizing it to arsenate. It consists of two subunits, a large subunit similar to members of the DMSO reductase family of molybdenum enzymes and a small subunit with a Rieske-type [2Fe-2S] cluster. The large subunit of ArOX contains the molybdenum site at which the oxidation of arsenite occurs. The small subunit contains a domain homologous to the Rieske domains of the cytochrome bc(1) and cytochrome b6f complexes as well as naphthalene 1,2-dioxygenase. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer.


Pssm-ID: 239558  Cd Length: 126  Bit Score: 45.07  E-value: 6.60e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148700440  76 GVCTHLGCvPIANAGDFGGYYCPCHGSHYDAS--GRIRKGPAPLNLE--VPAYEFTSDDVVVVG 135
Cdd:cd03476   53 ALCTHMGC-PLTYDPSNKTFVCPCHFSQFDPArgGQMVSGQATQNLPqiVLEYDEASGDIYAVG 115
Rieske_SoxF_SoxL cd03475
SoxF and SoxL family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain ...
 77-135 2.56e-04

SoxF and SoxL family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. SoxF is a subunit of the terminal oxidase supercomplex SoxM in the plasma membrane of Sulfolobus acidocaldarius that combines features of a cytochrome bc(1) complex and a cytochrome. The Rieske domain of SoxF has a 12 residue insertion which is not found in eukaryotic and bacterial Rieske proteins and is thought to influence the redox properties of the iron-sulfur cluster. SoxL is a Rieske protein which may be part of an archaeal bc-complex homologue whose physiological function is still unknown. SoxL has two features not seen in other Rieske proteins; (i) a significantly greater distance between the two cluster-binding sites and (ii) an unexpected Pro -> Asp substitution at one of the cluster binding sites. SoxF and SoxL are found in archaea and in bacteria.


Pssm-ID: 239557  Cd Length: 171  Bit Score: 38.63  E-value: 2.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148700440  77 VCTHLGCVPIA------------------NAGDFggyYCPCHGSHYD--ASGRIRKGPA--PLNLEVPAYEFTSDDVVVV 134
Cdd:cd03475   83 ICQHLGCQPPPivsypsyyppdkapglasKGAVI---HCCCHGSTYDpyKGGVVLTGPAprPLPAVILEYDSSTDDLYAV 159


                 .
gi 148700440 135 G 135
Cdd:cd03475  160 G 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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