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Conserved domains on  [gi|149729433|gb|ABR28239|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Onychognathus blythii]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 6.12e-157

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 443.49  E-value: 6.12e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPHTTNHMKQWYTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 149729433 321 TSPLVAILSTMSIILLPISPMVTAIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 6.12e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 443.49  E-value: 6.12e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPHTTNHMKQWYTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 149729433 321 TSPLVAILSTMSIILLPISPMVTAIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-283 6.21e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 102.12  E-value: 6.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   9 FALSLL--LGSTITISSNHWVMAWTGLEINTLAVLPLIS-KSHHPRAIEAATKYFLVQAAASTLILF------------- 72
Cdd:COG1007  105 YALLLFatLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgsln 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  73 -SSMTNAWYNGQWDITQLAcpTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMK----FPPITLLYMTSQ 147
Cdd:COG1007  185 lAGIAAALAAGGANSPLLL--LGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKiaafAALLRLLVEAFP 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 148 SLNP---TLLTTMAILSAALGGWMGLNQTQTRKILAFSS****--************LALLNFYL--YAMMTATVFLILN 220
Cdd:COG1007  263 GLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAgyLLLGLAAGTPLGVSAALFYLlaYLFMNLGAFAVIL 342

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 149729433 221 TI-KTLKLSTLMTTWA----KTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIA 283
Cdd:COG1007  343 LLsRKGGEAEEIEDLAglarRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAV 410
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-272 1.53e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.76  E-value: 1.53e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   23 SNHWVMAWTGLEINTLAVLPLI-SKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQWDITQLA-----CPTSSV 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   97 ILTAAIAM------KLGLAPFHFWFPEVLQGCPLTTGLLL-STAMKFPPI-----TLLYMTSQSLNPTLLTTMAILSAAL 164
Cdd:pfam00361  81 LLLLFLLIlvgflfKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYglirrSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  165 GGWMGLNQTQTRKILAFSS*----***************LALLNFYLYAMMTATVFL-----ILNTIKTLKLSTLMTTWA 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSIshmgYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 149729433  236 KTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVN 272
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVA 277
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 2.34e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.77  E-value: 2.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   14 LLGSTITISSNHWVMAWTGLEINTLAVLPLIS-KSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQWDITQLA-- 90
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLlf 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   91 ----------CPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMK---FPPITLLYMTSQS----LNPTL 153
Cdd:TIGR01770 192 lsngmlnislLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKiaiFAVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  154 LTTMAILSAALGGWMGLNQTQTRKILAFSS****--************LALLNFYL--YAMMTATVFLILNTIKTLKLS- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVgyILIGLLAGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 149729433  229 ----TLMTTWAKTPSLSAVLM-LTLLSLAGLPPLTGFLPKWLIIQELVNQEM 275
Cdd:TIGR01770 352 ieyiSDFAGLFKTNPILAILIlIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 6.12e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 443.49  E-value: 6.12e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAIL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPHTTNHMKQWYTNKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 149729433 321 TSPLVAILSTMSIILLPISPMVTAIV 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-345 2.27e-123

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 358.46  E-value: 2.27e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAIL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPHTTNHMKQWYTNKP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                        330       340
                 ....*....|....*....|....*
gi 149729433 321 TSPLVAILSTMSIILLPISPMVTAI 345
Cdd:MTH00070 321 TNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 7.98e-123

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 356.81  E-value: 7.98e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSlNPTLLTTMAIL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPHTTNHMKQW--YTN 318
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWrlPST 319

                        330       340
                 ....*....|....*....|....*...
gi 149729433 319 KPTSPLvAILSTMSIILLPISPMVTAIV 346
Cdd:MTH00135 320 QLTLPL-AISTTATLMLLPLTPAILALL 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-341 3.31e-107

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 317.17  E-value: 3.31e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAIL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPhTTNHMK-QW-YTN 318
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKmKWqFEN 319

                        330       340
                 ....*....|....*....|...
gi 149729433 319 KPTSPLVAILSTMSIILLPISPM 341
Cdd:MTH00105 320 TKPMTLLPTLIILSTMLLPLTPM 342
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-342 9.01e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 280.32  E-value: 9.01e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAIL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPHTTNHMKQWYTNKP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|..
gi 149729433 321 TSPLVAILSTMSIILLPISPMV 342
Cdd:MTH00200 321 SNLLVGLLLLLSILGLPLTPQL 342
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-336 4.95e-77

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 240.22  E-value: 4.95e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAIL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLPPHTTNHMKQWYTNKP 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330
                 ....*....|....*.
gi 149729433 321 TSPLVAILSTMSIILL 336
Cdd:MTH00041 321 ITVYGVILSILSSISI 336
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-341 9.79e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 179.63  E-value: 9.79e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   1 MNPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWY 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  81 NGqwditqLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTsqsLNPTLLTTMAIL 160
Cdd:MTH00160  82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 161 SAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 241 SAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIALLSLLSLFFYLRLAYCATITLppHTTNHMKQWYTNKP 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLN--YNKNKWNLKKKKNK 310

                        330       340
                 ....*....|....*....|.
gi 149729433 321 TSPLVAILSTMSIILLPISPM 341
Cdd:MTH00160 311 FSLILNFLSFISLFGLILSSL 331
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-275 1.15e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 145.41  E-value: 1.15e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   5 AKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQW 84
Cdd:MTH00144   5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  85 DitqlacptSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNP-TLLTTMAILSAA 163
Cdd:MTH00144  85 F--------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 164 LGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTiKTLKLSTLMTTWAKTPSLSAV 243
Cdd:MTH00144 157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWS-GDSGSMKDLGSLKPSYKTGLS 235

                        250       260       270
                 ....*....|....*....|....*....|..
gi 149729433 244 LMLTLLSLAGLPPLTGFLPKWLIIQELVNQEM 275
Cdd:MTH00144 236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSP 267
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 7-275 2.87e-39

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 141.84  E-value: 2.87e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   7 LIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSmtnawyNGQWDI 86
Cdd:MTH00011   9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  87 TQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTTMAILSAALGG 166
Cdd:MTH00011  83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 167 WMGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSLSAVLML 246
Cdd:MTH00011 163 LGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFI 242

                        250       260
                 ....*....|....*....|....*....
gi 149729433 247 TLLSLAGLPPLTGFLPKWLIIQELVNQEM 275
Cdd:MTH00011 243 MLLSLGGLPPFTGFMPKLMAIETLTSNSM 271
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-271 1.55e-30

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 118.24  E-value: 1.55e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   8 IFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMtnAWYNGQWDIT 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS--LSFSNLYLSL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  88 qlacpTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLymTSQSLNPTLLTTMAILSAALGGW 167
Cdd:MTH00197  80 -----LSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 168 MGLNQTQTRKILAFSS****************LALLNFYLYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSLSAVLMLT 247
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                        250       260
                 ....*....|....*....|....
gi 149729433 248 LLSLAGLPPLTGFLPKWLIIQELV 271
Cdd:MTH00197 233 FLSLGGLPPLSGFFLKWLILTSLL 256
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-274 1.06e-26

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 108.58  E-value: 1.06e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  13 LLLGSTITISSNHWVMAWTGLEINTLAVLPLI-SKSHHPRAIEAATKYFLVQAAASTLILFS-------------SMTNA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  79 WYNGQWDITQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYmtSQSLNPTLLTTMA 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 159 ILSAALGGWMGLNQTQTRKILAFSS**----**************LALLNFYLYAMMTATVFLILNTIKTLK--LSTLMT 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGhmgfVLWGIEIGSFESIQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSG 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 149729433 233 TWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQE 274
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQ 281
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-283 6.21e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 102.12  E-value: 6.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   9 FALSLL--LGSTITISSNHWVMAWTGLEINTLAVLPLIS-KSHHPRAIEAATKYFLVQAAASTLILF------------- 72
Cdd:COG1007  105 YALLLFatLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgsln 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  73 -SSMTNAWYNGQWDITQLAcpTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMK----FPPITLLYMTSQ 147
Cdd:COG1007  185 lAGIAAALAAGGANSPLLL--LGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKiaafAALLRLLVEAFP 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 148 SLNP---TLLTTMAILSAALGGWMGLNQTQTRKILAFSS****--************LALLNFYL--YAMMTATVFLILN 220
Cdd:COG1007  263 GLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAgyLLLGLAAGTPLGVSAALFYLlaYLFMNLGAFAVIL 342

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 149729433 221 TI-KTLKLSTLMTTWA----KTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIA 283
Cdd:COG1007  343 LLsRKGGEAEEIEDLAglarRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAV 410
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
9-281 4.62e-22

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 96.43  E-value: 4.62e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   9 FALSLL--LGSTITISSNHWVMAWTGLEINTLAVLPLIS-KSHHPRAIEAATKYFLVQAAASTLIL-------------- 71
Cdd:PRK05777 106 YLLVLFalLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLygmsllygatgsls 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  72 FSSMTNAWYNGQWDITQLAcpTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMK---FPPIT-LLYMTSQ 147
Cdd:PRK05777 186 FAGIAKALADGSGNSLLLL--FGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKiaaFAVLLrLLVVAFG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 148 SLNPT---LLTTMAILSAALGGWMGLNQTQTRKILAFSS****************LAL--LNFYL--YAMMTATVFLILN 220
Cdd:PRK05777 264 GLSEDwqqVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYLlaYLFMTLGAFGVIS 343

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 149729433 221 TIKT-LKLSTLMTTWA----KTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATI 281
Cdd:PRK05777 344 LLRRkGGEAESISDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVI 409
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-267 5.96e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 96.24  E-value: 5.96e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   8 IFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLIS-KSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQWDI 86
Cdd:MTH00199 101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  87 ----TQLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPTLLTtmAILSA 162
Cdd:MTH00199 181 qginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSI 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 163 ALGGWMGLNQTQTRKILAFSS*----***************LALLNFYLYAMMTATVFLILNTIKTLK--LSTLMTTWAK 236
Cdd:MTH00199 259 IYGAIGALNQTKIKRLLAYSGIghmgFILFGVAIGSFESIQASLIYMIIYVIMSICSFSIILSLKLTKglIVEVSGLSRK 338

                        250       260       270
                 ....*....|....*....|....*....|.
gi 149729433 237 TPSLSAVLMLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00199 339 NPVIALTLALTFLSIAGIPPLAGFLSKWLIL 369
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-272 1.53e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.76  E-value: 1.53e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   23 SNHWVMAWTGLEINTLAVLPLI-SKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQWDITQLA-----CPTSSV 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   97 ILTAAIAM------KLGLAPFHFWFPEVLQGCPLTTGLLL-STAMKFPPI-----TLLYMTSQSLNPTLLTTMAILSAAL 164
Cdd:pfam00361  81 LLLLFLLIlvgflfKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYglirrSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  165 GGWMGLNQTQTRKILAFSS*----***************LALLNFYLYAMMTATVFL-----ILNTIKTLKLSTLMTTWA 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSIshmgYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 149729433  236 KTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVN 272
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVA 277
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 2.34e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.77  E-value: 2.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   14 LLGSTITISSNHWVMAWTGLEINTLAVLPLIS-KSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQWDITQLA-- 90
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLlf 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   91 ----------CPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMK---FPPITLLYMTSQS----LNPTL 153
Cdd:TIGR01770 192 lsngmlnislLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKiaiFAVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  154 LTTMAILSAALGGWMGLNQTQTRKILAFSS****--************LALLNFYL--YAMMTATVFLILNTIKTLKLS- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVgyILIGLLAGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 149729433  229 ----TLMTTWAKTPSLSAVLM-LTLLSLAGLPPLTGFLPKWLIIQELVNQEM 275
Cdd:TIGR01770 352 ieyiSDFAGLFKTNPILAILIlIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-283 2.95e-18

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 85.20  E-value: 2.95e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  13 LLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQWDITQLAC- 91
Cdd:COG0651  116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAr 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  92 ---------PTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNP--------TLL 154
Cdd:COG0651  196 laeldpgllLAAFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLTKVGVYAILRVLTLLFGadpalflgTLL 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 155 TTMAILSAALGGWMGLNQTQTRKILAFSS****************LALLNFYLY----AMMTATVFL----ILNTIKTLK 226
Cdd:COG0651  276 LVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALLFLaagaIERATGTRD 355

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 149729433 227 LSTLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIA 283
Cdd:COG0651  356 LDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLL 412
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-267 2.79e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 79.90  E-value: 2.79e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   3 PQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAI---------EAATKYFLVQAAASTLILF- 72
Cdd:MTH00198 187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFg 266

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  73 ----------SSMTNAWYNGQWDITQLACPTSSV---ILTAAIAMKLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPI 139
Cdd:MTH00198 267 calyfgftgnEGMLGTILSATLETTNIELRQGSLgylFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVY 346

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 140 TLLymTSQSLNPTLLTTMAILSAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMM-TATVFLI 218
Cdd:MTH00198 347 ILL--TSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTyLVSALAS 424

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 149729433 219 LNTIKTL------------------------KLSTLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00198 425 FTVICTLeefgtrtptsrqrdgsfgnynlvrRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-263 2.72e-12

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 67.38  E-value: 2.72e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  50 PRAIEAATKYFLVQAAASTLILF-SSMTNAWYNGQWDITQ----------LACPTSSVILTAAIAMKLGLAPFHFWFPEV 118
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSAialalitspsLGLALALVFVIAGIAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 119 LQGCPLTTGLLLSTAMKFP----PITLLYMTSQSLNP---TLLTTMAILSAALGGWMGLNQTQTRKILAFSS****--** 189
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAgfVM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 190 **********LALLNFYL--YAMMTATVF--LILNTIKT--LKLSTLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK02504 317 IGLVAGTEAGYASMVFYLlaYLFMNLGAFacVILFSLRTgtDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
ndhB CHL00049
NADH dehydrogenase subunit 2
 7-263 6.52e-12

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 66.18  E-value: 6.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   7 LIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHP-RAIEAATKYFLVQAAASTLILF------------- 72
Cdd:CHL00049 114 LLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVYgfswlyglsggei 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  73 --SSMTNAWYNGQWDITqLACPTSSVILTAAIAMKLGLAPFHFWFPEVLQGCPL-----------TTGLLLSTAMkfppI 139
Cdd:CHL00049 194 elQEIVNGLINTQMYNS-PGISIALIFITVGIGFKLSLAPFHQWTPDVYEGSPTpvvaflsvtskVAASALATRI----F 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 140 TLLYMTSQSLNPTLLTTMAILSAALGGWMGLNQTQTRKILAFSS****************lALLNFYLYAMMTATVFLIL 219
Cdd:CHL00049 269 DIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIV----GDSNDGYASMITYMLFYIF 344

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 149729433 220 NTIKTLKLSTLMTT-------------WAKTPSLSAVLMLTLLSLAGLPPLTGFLPK 263
Cdd:CHL00049 345 MNLGTFACIVLFGLrtgtdnirdyaglYTKDPFLALSLALCLLSLGGIPPLAGFFGK 401
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-282 5.29e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 54.11  E-value: 5.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  33 LEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFS-----SMTNawYNGQWDITQLACPTSSV-----ILTAAI 102
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvgllyGVTG--TLNMADLAGALAENPTVvtafgFVLLAL 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 103 AMKLGLAPFHFWFPEVLQGCPLTTGLLLS---TAMKFPPITLLY--------MTSQSLNpTLLTTMAILSAALGGWMGLN 171
Cdd:PRK08375 213 ALKAAVFPLHTWLPRAYPAAPPVVTALLSglvTKVAVYALIRIYftvfggdfRFALGLG-WLLAVLALLSMLVGSLAALG 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 172 QTQTRKILAFSS****************LALLN--FYL--YAMMTATVFL----ILNTIKTLKLSTLMTTWAKTPSLSAV 243
Cdd:PRK08375 292 QDDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLaagaIEVTYGTRRLSELSGLGRRMPLTAAA 371

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 149729433 244 LMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATII 282
Cdd:PRK08375 372 FAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVL 410
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 8.00e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 53.56  E-value: 8.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  33 LEINTLAVLPLIS-KSHHPRAIEAATKYFLVQAAASTLILFS-----------SMTNAWYNGQWDITQLAcPTSSVILTA 100
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygtlNMAYLAVKMSENPTVVA-KIALALFIA 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 101 AIAMKLGLAPFHFWFPEVLQGCP--LTTGLLLSTAMKFPPI--TLLYMTSQSLNPT----LLTTMAILSAALGGWMGLNQ 172
Cdd:PRK08376 229 GLAMKSGAVPVHMWLPDAYPAAPssISAMLLVIKQAGLYALarVLFSIYGPAINLAtvgwVIIILGCLTMFVGVAMAVVQ 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 173 TQTRKILAFSS----------------****************LALLNFYLYAMMTATVFL----ILNTIKTLKLSTLMT 232
Cdd:PRK08376 309 KDVKRLLAYHSvsqigymllglgvglaALGDPAMASYGEIALAGGIYHIVNHALYKALLFLtagaVIYETGTRNLNELGG 388

                        250       260       270
                 ....*....|....*....|....*....|....
gi 149729433 233 TWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK08376 389 LARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-275 8.55e-08

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 53.85  E-value: 8.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   2 NPQAKLIFALSLLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHpRAIEAATKYFLVQAAASTLILFSSMTNAWYN 81
Cdd:PRK08668  96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKT 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  82 GQWDIT---QLACPTSS--------VILTAAIAMKLGLAPFHFWFPEVLQGCPLT--------------TGLLLSTAMkF 136
Cdd:PRK08668 175 GTFDFAdisQGLINDTStgfalivfLFLLAFGVAKAGIFPLHVWAPDAYSEAPQSfsavlsgqlsklgaYGFLLVLYV-L 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 137 PPITLLYMTSQSLNPTLLTTMAI----LSAALGGWMGLNQTQTRKILAFSS****************L----ALLNFYLY 208
Cdd:PRK08668 254 PGTKLFSEFGTYRGVPLFNYILAwlgnISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLgfagGLFHVFNH 333

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 149729433 209 AMMTATVFLILNTI----KTLKLSTLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEM 275
Cdd:PRK08668 334 ALFKGLFFLIFAAViyrtGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGM 404
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 89-283 2.60e-06

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 49.15  E-value: 2.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  89 LACPTSSVILTAAIAM-------KLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLL------YMTSQSLNPTLLT 155
Cdd:PRK12644 193 LADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVarlapgFADVPVWRPTVLV 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 156 tMAILSAALGGWMGLNQTQTRKILAF---SS****************LALLNFYL-YAMMTATVFLILNTIK----TLKL 227
Cdd:PRK12644 273 -LGLATMLLGGWRALRQHDLKLILAYgtvSQLGFLTVLVGIGTRDAALAGLAMLLaHALFKAALFLVVGIIDhstgTRDI 351

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 149729433 228 STLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIA 283
Cdd:PRK12644 352 RKLSGLGRRQPVLAVVAALAAASMAGLPPLLGFVAKEAALEAVLHDGALGPAGPVV 407
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-271 9.56e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 47.25  E-value: 9.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  33 LEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQWDITQL--ACPTSSVILTAAIAMKLGLAP 110
Cdd:PRK07234 123 LEVLSIATFLLVAYPRTDRAIWVGLRYLFYSNVAMLFYLIGAVLVYQANGTFAFSGLatADPEAFALIALGLLVKGGIFV 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 111 FHFWFPEVLQGCPLTTGLLLSTAMK----FPPITLLYMTSQSLNPtlLTTMAILSAALGGWMGLNQTQTRKILAFSS*** 186
Cdd:PRK07234 203 SGLWLPLTHSEAEPPVSALLSGVVVkagvFPLVRCALDVPGLDLI--VRIFGVGTALLGVLFALLEKDLKRMLAFSTISQ 280

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 187 *************LALLnfylYAMMTATVFLILNTIKTLKLSTLMTTWAKTPSLSAVLMLTLlSLAGLPPLTGFLPKWLI 266
Cdd:PRK07234 281 LGFILAAPLVGGLYALA----HGLVKSTLFLCAGALPSRNFTELISQMLGIGKWIPLTMASF-SIAGFPLLAGFVSKVLT 355


                 ....*
gi 149729433 267 IQELV 271
Cdd:PRK07234 356 LKNLL 360
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 295-340 1.66e-05

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 41.86  E-value: 1.66e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 149729433  295 RLAYCATITLPPHTTNHMKQWYTNKP-TSPLVAILSTMSIILLPISP 340
Cdd:pfam06444   5 RLSYSTTLTLFPNTNNSKMKWRFNSTkNTLLLPTLTTLSILLLPLTP 51
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-268 5.14e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 44.93  E-value: 5.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   50 PRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQW----DITQLACPTSS-----VILTAAIAMKLGLAPFHFWFPEV-- 118
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGTfdllELLNLPLPFGVqtwlfLAFFIAFAVKVPLFPLHTWLPDAhv 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  119 ---LQGCPLTTGLLLSTA----MKFpPITLLYMTSQSLNPtLLTTMAILSAALGGWMGLNQTQTRKILAFSS******** 191
Cdd:TIGR01972 232 eapTAGSVILAGVLLKMGtygfLRF-NLPLFPDASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  192 ********LALLN--FYLYA--MMTATVFLILNTI----KTLKLSTLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPK 263
Cdd:TIGR01972 310 LGIFSFNELGISGavFQMIShgLITAALFLLVGVLyeraHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGE 389


                  ....*
gi 149729433  264 WLIIQ 268
Cdd:TIGR01972 390 FLILL 394
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-283 5.66e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 44.69  E-value: 5.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  49 HPRAIEAATKYFLVQAAASTLILFSSMTNAWYNGQW-----DITQLACPTSSVILT-----AAIAMKLGLAPFHFWFPEV 118
Cdd:COG1008  156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTAQLLLflaffIAFAVKVPMFPFHTWLPDA 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 119 LQGCPLTTGLLLSTAM---------KFpPITLLYMTSQSLNPTLLtTMAILSAALGGWMGLNQTQTRKILAFSS****** 189
Cdd:COG1008  236 HVEAPTAGSVLLAGVLlkmggygllRF-ALPLFPEASAYFAPLLA-ALGVIGIIYGALVALAQTDLKRLIAYSS------ 307

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 190 **********LALLNFYLYAM------------MTATVFLILNTI----KTLKLSTLMTTWAKTPSLSAVLMLTLLSLAG 253
Cdd:COG1008  308 --VSHMGFVLLGIFALNPLGLqgavlqmvshglITAALFLLVGVLydrtHTRDIADLGGLAKRMPVLAALFLLAALASLG 385

                        250       260       270
                 ....*....|....*....|....*....|
gi 149729433 254 LPPLTGFLPKWLIIQELVnqEMAPAATIIA 283
Cdd:COG1008  386 LPGTSGFVGEFLVLLGAF--QVNPWLAILA 413
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 110-283 3.75e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 42.21  E-value: 3.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 110 PFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLymtsQSLNP---------TLLTTMAILSAALGGWMGLNQTQTRKILA 180
Cdd:PRK12647 213 PFHFWLPNAMEAPTPVSAYLHSATMVKAGIYLL----ARLNPvlggtplwqTILPLFGGLTMLTGALLAVRQTDLKLILA 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 181 FSS****************LALLNFYLY----AMMTATVFLILNTIK----TLKLSTLMTTWAKTPSLSAVLMLTLLSLA 252
Cdd:PRK12647 289 YSTVSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAGIIDhetgTRDITKLGGLRRAMPITAAAALLAALSMA 368

                        170       180       190
                 ....*....|....*....|....*....|.
gi 149729433 253 GLPPLTGFLPKWLIIQELVNQEMAPAATIIA 283
Cdd:PRK12647 369 GLPPLFGFLAKELIYEALLEAPLWSLILTVA 399
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 8-268 4.10e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 41.84  E-value: 4.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   8 IFALSLLLgstiTISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYF---------------LVQAAASTLILF 72
Cdd:PRK06458 116 LFLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIiicsvgvafalfgtiLVYANAATVMGD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  73 SSMTNAW-----YNGQWD--ITQLAcptsSVILTAAIAMKLGLAPFHFWFPEVLQGCP-----LTTGLLLSTAMkFPPIT 140
Cdd:PRK06458 192 GEMAILWtellkHASLLDptLMKLA----FVFLLIGFGTKVGLFPMHAWLPDAHSEAPspvsaLLSGVLLNVAL-YAVLR 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 141 LLYMTSQSLNP----TLLTTMAILSAALGGWMGLNQTQTRKILAFSS****************LALLNFYLYAMMTA--- 213
Cdd:PRK06458 267 YYILIDAAIGSdfpgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHSltk 346

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 214 -----TVFLILNTIKTLKLSTLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK06458 347 saiffASGNVLQKYGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILT 406
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
92-268 6.43e-04

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 41.47  E-value: 6.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  92 PTSSVILTAAIAMKLGLAPFhFWFPEVLQGCPLTTGLLLSTAMK-------FPPITLLYMTSQSLNPTLLTTMAILSAAL 164
Cdd:PRK12663 207 TTIALLFLLAFGMKAALFPF-MWLPAAYHTPNTEVAALFAALLTkvgiyalIRVFTLLFPQERELLHPLLATMAAITMVI 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 165 GGWMGLNQTQTRKILAFSS****************LALLNFYLYAM-----MTAtVFLILNTIKTL----KLSTLMTTWA 235
Cdd:PRK12663 286 GALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGINGAIFYLVhdmvvKTA-LFLIAGSLVRLtgyrSLQYLGGLYR 364

                        170       180       190
                 ....*....|....*....|....*....|...
gi 149729433 236 KTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK12663 365 KEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQ 397
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-283 1.24e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 40.57  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433   2 NPQAKLIFALSLLLGSTITISSNHWVMaWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAASTLILFSSMT---NA 78
Cdd:PRK06589 115 SSRFLFFFNLTILIGVLIALSSDLFTM-FVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAVIliyTK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  79 WYNGQW-DITQLACPTSSVILTAAIAM--KLGLAPFHFWFPEVLQGCPLTTGLLLSTAM----KFPPITLLYMTSQSLNP 151
Cdd:PRK06589 194 TGNLDFvSGGLFSKNQSIILLLMFIYGiaKTAIFPVHSWLPAAMVAHYPVSALLHAVIVvktgLFCIYKILLYIFGLSYL 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433 152 TLLTTM-------AILSAALGGWMGLNQTQTRKILAFSS****************LALLNFYLY----AMMTATVFLILN 220
Cdd:PRK06589 274 QRIFAEfnwlifiPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHlvshSFAKICLFYSMG 353

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 149729433 221 TIKTLK----LSTLMTTWAKTPSLSAVLMLTLLSLAGLPPLTGFLPKWLIIQELVNQEMAPAATIIA 283
Cdd:PRK06589 354 SIYSLKkedqVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVM 420
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-183 3.96e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 38.97  E-value: 3.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  13 LLLGSTITISSNHWVMAWTGLEINTLAVLPLISKSHHPRAIEAATKYFLVQAAA------STLILFSSMTNAWYNGQWDI 86
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149729433  87 TQLACPTS----SVILTAAIAM------KLGLAPFHFWFPEVLQGCPLTTGLLLSTAMKFPPITLLYMTSQSLNPT---- 152
Cdd:PRK08676 191 TELAAHASllspSVLGASFLFIfigflaKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLRQSgaae 270

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 149729433 153 ----LLTTMAILSAALGGWMGLNQTQTRKILAFSS 183
Cdd:PRK08676 271 qfsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSS 305
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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