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Conserved domains on  [gi|1566185496|ref|NP_001355208|]
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small membrane A-kinase anchor protein [Mus musculus]

Protein Classification

SmAKAP domain-containing protein( domain architecture ID 10633476)

SmAKAP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SmAKAP pfam15127
Small membrane A-kinase anchor protein; SmAKAP is a small membrane-bound PKA-RI-specific ...
 1-100 1.85e-48

Small membrane A-kinase anchor protein; SmAKAP is a small membrane-bound PKA-RI-specific protein kinase A-anchoring protein, referred to as small membrane-AKAP. It is probably tethered to the plasma membrane most through a dual acylation of its N-terminal Met-Gly-Cys- motif (myristoylation and palmitoylation, respectively). It specifically targets PKA-RI isoforms to the plasma membrane. It localizes to plasma membranes, is enriched at cell-cell junctions and associates with filopodia.


:

Pssm-ID: 464517  Cd Length: 97  Bit Score: 149.58  E-value: 1.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566185496   1 MGCMKSKETFPFPTTLDIDKLHESEEAFIPDDSSqYRTPSPgeqQQVQ-EVKKLPEPGAVIGALILEFADRLASEIVEDA 79
Cdd:pfam15127   1 MGCMKSKQTFPFPTTLEMEKQHGSEEKFMPEERC-PRMPSP---VLVQeEVKESPEPSARANPVLLEYAHRLSEEIVADA 76

                          90       100
                  ....*....|....*....|.
gi 1566185496  80 LQQWACENIQYYNIPYIESEG 100
Cdd:pfam15127  77 LQQWAEVNIKYSDIPYIESEG 97
 
Name Accession Description Interval E-value
SmAKAP pfam15127
Small membrane A-kinase anchor protein; SmAKAP is a small membrane-bound PKA-RI-specific ...
 1-100 1.85e-48

Small membrane A-kinase anchor protein; SmAKAP is a small membrane-bound PKA-RI-specific protein kinase A-anchoring protein, referred to as small membrane-AKAP. It is probably tethered to the plasma membrane most through a dual acylation of its N-terminal Met-Gly-Cys- motif (myristoylation and palmitoylation, respectively). It specifically targets PKA-RI isoforms to the plasma membrane. It localizes to plasma membranes, is enriched at cell-cell junctions and associates with filopodia.


Pssm-ID: 464517  Cd Length: 97  Bit Score: 149.58  E-value: 1.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566185496   1 MGCMKSKETFPFPTTLDIDKLHESEEAFIPDDSSqYRTPSPgeqQQVQ-EVKKLPEPGAVIGALILEFADRLASEIVEDA 79
Cdd:pfam15127   1 MGCMKSKQTFPFPTTLEMEKQHGSEEKFMPEERC-PRMPSP---VLVQeEVKESPEPSARANPVLLEYAHRLSEEIVADA 76

                          90       100
                  ....*....|....*....|.
gi 1566185496  80 LQQWACENIQYYNIPYIESEG 100
Cdd:pfam15127  77 LQQWAEVNIKYSDIPYIESEG 97
 
Name Accession Description Interval E-value
SmAKAP pfam15127
Small membrane A-kinase anchor protein; SmAKAP is a small membrane-bound PKA-RI-specific ...
 1-100 1.85e-48

Small membrane A-kinase anchor protein; SmAKAP is a small membrane-bound PKA-RI-specific protein kinase A-anchoring protein, referred to as small membrane-AKAP. It is probably tethered to the plasma membrane most through a dual acylation of its N-terminal Met-Gly-Cys- motif (myristoylation and palmitoylation, respectively). It specifically targets PKA-RI isoforms to the plasma membrane. It localizes to plasma membranes, is enriched at cell-cell junctions and associates with filopodia.


Pssm-ID: 464517  Cd Length: 97  Bit Score: 149.58  E-value: 1.85e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566185496   1 MGCMKSKETFPFPTTLDIDKLHESEEAFIPDDSSqYRTPSPgeqQQVQ-EVKKLPEPGAVIGALILEFADRLASEIVEDA 79
Cdd:pfam15127   1 MGCMKSKQTFPFPTTLEMEKQHGSEEKFMPEERC-PRMPSP---VLVQeEVKESPEPSARANPVLLEYAHRLSEEIVADA 76

                          90       100
                  ....*....|....*....|.
gi 1566185496  80 LQQWACENIQYYNIPYIESEG 100
Cdd:pfam15127  77 LQQWAEVNIKYSDIPYIESEG 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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