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CTP synthase, partial [Fibrobacter succinogenes subsp. succinogenes S85]
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
PyrG super family | cl33917 | CTP synthase (UTP-ammonia lyase) [Nucleotide transport and metabolism]; CTP synthase ... |
1-133 | 4.15e-84 | |||
CTP synthase (UTP-ammonia lyase) [Nucleotide transport and metabolism]; CTP synthase (UTP-ammonia lyase) is part of the Pathway/BioSystem: Pyrimidine biosynthesis The actual alignment was detected with superfamily member COG0504: Pssm-ID: 440270 [Multi-domain] Cd Length: 535 Bit Score: 255.32 E-value: 4.15e-84
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Name | Accession | Description | Interval | E-value | |||
PyrG | COG0504 | CTP synthase (UTP-ammonia lyase) [Nucleotide transport and metabolism]; CTP synthase ... |
1-133 | 4.15e-84 | |||
CTP synthase (UTP-ammonia lyase) [Nucleotide transport and metabolism]; CTP synthase (UTP-ammonia lyase) is part of the Pathway/BioSystem: Pyrimidine biosynthesis Pssm-ID: 440270 [Multi-domain] Cd Length: 535 Bit Score: 255.32 E-value: 4.15e-84
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pyrG | PRK05380 | CTP synthetase; Validated |
1-133 | 1.31e-83 | |||
CTP synthetase; Validated Pssm-ID: 235437 [Multi-domain] Cd Length: 533 Bit Score: 253.79 E-value: 1.31e-83
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GATase1_CTP_Synthase | cd01746 | Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; ... |
1-133 | 2.34e-72 | |||
Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase (CTP). CTP is involved in pyrimidine ribonucleotide/ribonucleoside metabolism. CTPs produce CTP from UTP and glutamine and regulate intracellular CTP levels through interactions with four ribonucleotide triphosphates. The enzyme exists as a dimer of identical chains that aggregates as a tetramer. CTP is derived form UTP in three separate steps involving two active sites. In one active site, the UTP O4 oxygen is activated by Mg-ATP-dependent phosphorylation, followed by displacement of the resulting 4-phosphate moiety by ammonia. At a separate site, ammonia is generated via rate limiting glutamine hydrolysis (glutaminase) activity. A gated channel that spans between the glutamine hydrolysis and amidoligase active sites provides a path for ammonia diffusion. CTPs belong to the triad family of amidotransferases having a conserved Cys-His-Glu catalytic triad in the glutaminase active site. Pssm-ID: 153217 [Multi-domain] Cd Length: 235 Bit Score: 215.88 E-value: 2.34e-72
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PyrG | TIGR00337 | CTP synthase; CTP synthase is involved in pyrimidine ribonucleotide/ribonucleoside metabolism. ... |
1-133 | 5.19e-70 | |||
CTP synthase; CTP synthase is involved in pyrimidine ribonucleotide/ribonucleoside metabolism. The enzyme catalyzes the reaction L-glutamine + H2O + UTP + ATP = CTP + phosphate + ADP + L-glutamate. The enzyme exists as a dimer of identical chains that aggregates as a tetramer. This gene has been found circa 500 bp 5' upstream of enolase in both beta (Nitrosomonas europaea) and gamma (E.coli) subdivisions of proteobacterium (FEMS Microbiol Lett 1998 Aug 1;165(1):153-7). [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis] Pssm-ID: 273021 [Multi-domain] Cd Length: 525 Bit Score: 218.74 E-value: 5.19e-70
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GATase | pfam00117 | Glutamine amidotransferase class-I; |
1-133 | 1.11e-23 | |||
Glutamine amidotransferase class-I; Pssm-ID: 395067 [Multi-domain] Cd Length: 188 Bit Score: 90.37 E-value: 1.11e-23
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Name | Accession | Description | Interval | E-value | |||
PyrG | COG0504 | CTP synthase (UTP-ammonia lyase) [Nucleotide transport and metabolism]; CTP synthase ... |
1-133 | 4.15e-84 | |||
CTP synthase (UTP-ammonia lyase) [Nucleotide transport and metabolism]; CTP synthase (UTP-ammonia lyase) is part of the Pathway/BioSystem: Pyrimidine biosynthesis Pssm-ID: 440270 [Multi-domain] Cd Length: 535 Bit Score: 255.32 E-value: 4.15e-84
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pyrG | PRK05380 | CTP synthetase; Validated |
1-133 | 1.31e-83 | |||
CTP synthetase; Validated Pssm-ID: 235437 [Multi-domain] Cd Length: 533 Bit Score: 253.79 E-value: 1.31e-83
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GATase1_CTP_Synthase | cd01746 | Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; ... |
1-133 | 2.34e-72 | |||
Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase (CTP). CTP is involved in pyrimidine ribonucleotide/ribonucleoside metabolism. CTPs produce CTP from UTP and glutamine and regulate intracellular CTP levels through interactions with four ribonucleotide triphosphates. The enzyme exists as a dimer of identical chains that aggregates as a tetramer. CTP is derived form UTP in three separate steps involving two active sites. In one active site, the UTP O4 oxygen is activated by Mg-ATP-dependent phosphorylation, followed by displacement of the resulting 4-phosphate moiety by ammonia. At a separate site, ammonia is generated via rate limiting glutamine hydrolysis (glutaminase) activity. A gated channel that spans between the glutamine hydrolysis and amidoligase active sites provides a path for ammonia diffusion. CTPs belong to the triad family of amidotransferases having a conserved Cys-His-Glu catalytic triad in the glutaminase active site. Pssm-ID: 153217 [Multi-domain] Cd Length: 235 Bit Score: 215.88 E-value: 2.34e-72
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PyrG | TIGR00337 | CTP synthase; CTP synthase is involved in pyrimidine ribonucleotide/ribonucleoside metabolism. ... |
1-133 | 5.19e-70 | |||
CTP synthase; CTP synthase is involved in pyrimidine ribonucleotide/ribonucleoside metabolism. The enzyme catalyzes the reaction L-glutamine + H2O + UTP + ATP = CTP + phosphate + ADP + L-glutamate. The enzyme exists as a dimer of identical chains that aggregates as a tetramer. This gene has been found circa 500 bp 5' upstream of enolase in both beta (Nitrosomonas europaea) and gamma (E.coli) subdivisions of proteobacterium (FEMS Microbiol Lett 1998 Aug 1;165(1):153-7). [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis] Pssm-ID: 273021 [Multi-domain] Cd Length: 525 Bit Score: 218.74 E-value: 5.19e-70
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PLN02327 | PLN02327 | CTP synthase |
1-133 | 5.50e-46 | |||
CTP synthase Pssm-ID: 215186 [Multi-domain] Cd Length: 557 Bit Score: 156.34 E-value: 5.50e-46
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GATase | pfam00117 | Glutamine amidotransferase class-I; |
1-133 | 1.11e-23 | |||
Glutamine amidotransferase class-I; Pssm-ID: 395067 [Multi-domain] Cd Length: 188 Bit Score: 90.37 E-value: 1.11e-23
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PRK06186 | PRK06186 | hypothetical protein; Validated |
1-133 | 1.39e-19 | |||
hypothetical protein; Validated Pssm-ID: 180452 [Multi-domain] Cd Length: 229 Bit Score: 80.78 E-value: 1.39e-19
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GATase1_2 | cd01745 | Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; This group ... |
101-133 | 9.83e-06 | |||
Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase. Pssm-ID: 153216 [Multi-domain] Cd Length: 189 Bit Score: 42.95 E-value: 9.83e-06
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puuD | PRK11366 | gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional |
100-133 | 1.25e-03 | |||
gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional Pssm-ID: 183101 [Multi-domain] Cd Length: 254 Bit Score: 37.19 E-value: 1.25e-03
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Blast search parameters | ||||
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