NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|158286949|ref|XP_309025|]
View 

AGAP006718-PA [Anopheles gambiae str. PEST]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
13-446 3.20e-125

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 370.98  E-value: 3.20e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  13 RRNLLTTLTILGVIVGIALGLGLRAVPAEgdswsqrdvtYINYVGDLFLRTLKALILPLIVSSLIAAVGSL-DLSLSKKI 91
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVAA----------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRI 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  92 GGRAVLYYLATTVLAVILGIVLVVTIKPGSdrdGGEADASDAPQRNVTTVDTLLDLVRNMFPPNLVQActqqyqtvlkpp 171
Cdd:COG1301   71 GGKTLLYFLVTTTIALVIGLVVANLFQPGA---GLNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA------------ 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 172 askpdetdiyrwtitgaYADGmNILGLVVASIVFGVALGATKRENALVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLIAA 251
Cdd:COG1301  136 -----------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAA 197

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 252 KILEIEdlGDVFGKLGLYFAVVAGGILFHGFVVLSLLFFLFTRNNPLKFIANMGQALATAFGTSSSSATLPVTMQCLEEK 331
Cdd:COG1301  198 TVAKYG--LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEK 275

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 332 NNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLVMVLDTVG 411
Cdd:COG1301  276 LGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVG 355

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 158286949 412 LPAEDVSLIIAVDWLLDRFRTLVNVLGDSFGAAIV 446
Cdd:COG1301  356 LPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
13-446 3.20e-125

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 370.98  E-value: 3.20e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  13 RRNLLTTLTILGVIVGIALGLGLRAVPAEgdswsqrdvtYINYVGDLFLRTLKALILPLIVSSLIAAVGSL-DLSLSKKI 91
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVAA----------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRI 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  92 GGRAVLYYLATTVLAVILGIVLVVTIKPGSdrdGGEADASDAPQRNVTTVDTLLDLVRNMFPPNLVQActqqyqtvlkpp 171
Cdd:COG1301   71 GGKTLLYFLVTTTIALVIGLVVANLFQPGA---GLNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA------------ 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 172 askpdetdiyrwtitgaYADGmNILGLVVASIVFGVALGATKRENALVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLIAA 251
Cdd:COG1301  136 -----------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAA 197

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 252 KILEIEdlGDVFGKLGLYFAVVAGGILFHGFVVLSLLFFLFTRNNPLKFIANMGQALATAFGTSSSSATLPVTMQCLEEK 331
Cdd:COG1301  198 TVAKYG--LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEK 275

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 332 NNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLVMVLDTVG 411
Cdd:COG1301  276 LGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVG 355

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 158286949 412 LPAEDVSLIIAVDWLLDRFRTLVNVLGDSFGAAIV 446
Cdd:COG1301  356 LPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
SDF pfam00375
Sodium:dicarboxylate symporter family;
17-448 1.73e-120

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 358.37  E-value: 1.73e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949   17 LTTLTILGVIVGIALGLglravpaegdsWSQRDVTYINYVGDLFLRTLKALILPLIVSSLIAAVGSL-DLSLSKKIGGRA 95
Cdd:pfam00375   1 LLLQILIALVLGILIGL-----------FFPELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKT 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949   96 VLYYLATTVLAVILGIVLVVTIKPGSDRDGGEADASDAPqrnVTTVDTLLDLVRNMFPPNLVQACTQQyqtvlkppaskp 175
Cdd:pfam00375  70 LLYFLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAK---AAEAPSLLDFILNIIPSNIFEALAEG------------ 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  176 detdiyrwtitgayadgmNILGLVVASIVFGVALGATKRENALVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLIAAKILE 255
Cdd:pfam00375 135 ------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  256 IEdlGDVFGKLGLYFAVVAGGILFHGFVVLSLLFFLFTRNNPLKFIANMGQALATAFGTSSSSATLPVTMQCLEEKNNID 335
Cdd:pfam00375 197 YG--LGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVS 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  336 PRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLVMVLDTVGLPAE 415
Cdd:pfam00375 275 ESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLE 354

                         410       420       430
                  ....*....|....*....|....*....|...
gi 158286949  416 DVSLIIAVDWLLDRFRTLVNVLGDSFGAAIVYH 448
Cdd:pfam00375 355 GIALILAIDRLLDMFRTAVNVTGDAAAAVIVAK 387
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 22-453 1.33e-42

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 156.85  E-value: 1.33e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  22 ILGVIVGIALGLGLRAVPAEGDSWSqrdVTYINYVGDLFLRTLKALILPLIVSSL---IAAVGslDLSLSKKIGGRAVLY 98
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDWLV---SNLLSPAGDIFIHLIKMIVVPIVISTLivgIAGVG--DAKQLGRIGAKTIIY 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  99 YLATTVLAVILGIVLVVTIKPGSDRDGGEADASDAPQRNVTTVD------TLLDLVRNMFPPNlvqactqqyqtvlkppa 172
Cdd:PRK11283  88 FEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEvqshshGLMGTILSLIPTN----------------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 173 skpdetdiyrwtITGAYADGmNILGLVVASIVFGVALG---ATKRENalVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLI 249
Cdd:PRK11283 151 ------------IFASMAKG-EMLPIIFFSVLFGLGLSslpATHREP--LVTVFRSVSETMFKVTHMVMRYAPVGVFALI 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 250 AAKILEiedlgdvFG-----KLGLYFAVVAGGILFHGFVVLSLLFFLFtRNNPLKFIANMGQALATAFGTSSSSATLPVT 324
Cdd:PRK11283 216 AVTVAN-------FGfaslwPLAKLVLLVYFAILFFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLPRI 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 325 MQCLEeKNNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLV 404
Cdd:PRK11283 288 IEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLL 366

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 158286949 405 MVLDTVGLPAEDVSLIIAVDWLLDRFRTLVNVLGDSFGAAIV------YHYSKAE 453
Cdd:PRK11283 367 ATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIakwehkFDRKKAL 421
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
13-446 3.20e-125

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 370.98  E-value: 3.20e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  13 RRNLLTTLTILGVIVGIALGLGLRAVPAEgdswsqrdvtYINYVGDLFLRTLKALILPLIVSSLIAAVGSL-DLSLSKKI 91
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVAA----------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRI 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  92 GGRAVLYYLATTVLAVILGIVLVVTIKPGSdrdGGEADASDAPQRNVTTVDTLLDLVRNMFPPNLVQActqqyqtvlkpp 171
Cdd:COG1301   71 GGKTLLYFLVTTTIALVIGLVVANLFQPGA---GLNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA------------ 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 172 askpdetdiyrwtitgaYADGmNILGLVVASIVFGVALGATKRENALVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLIAA 251
Cdd:COG1301  136 -----------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAA 197

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 252 KILEIEdlGDVFGKLGLYFAVVAGGILFHGFVVLSLLFFLFTRNNPLKFIANMGQALATAFGTSSSSATLPVTMQCLEEK 331
Cdd:COG1301  198 TVAKYG--LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEK 275

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 332 NNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLVMVLDTVG 411
Cdd:COG1301  276 LGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVG 355

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 158286949 412 LPAEDVSLIIAVDWLLDRFRTLVNVLGDSFGAAIV 446
Cdd:COG1301  356 LPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
SDF pfam00375
Sodium:dicarboxylate symporter family;
17-448 1.73e-120

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 358.37  E-value: 1.73e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949   17 LTTLTILGVIVGIALGLglravpaegdsWSQRDVTYINYVGDLFLRTLKALILPLIVSSLIAAVGSL-DLSLSKKIGGRA 95
Cdd:pfam00375   1 LLLQILIALVLGILIGL-----------FFPELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKT 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949   96 VLYYLATTVLAVILGIVLVVTIKPGSDRDGGEADASDAPqrnVTTVDTLLDLVRNMFPPNLVQACTQQyqtvlkppaskp 175
Cdd:pfam00375  70 LLYFLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAK---AAEAPSLLDFILNIIPSNIFEALAEG------------ 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  176 detdiyrwtitgayadgmNILGLVVASIVFGVALGATKRENALVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLIAAKILE 255
Cdd:pfam00375 135 ------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  256 IEdlGDVFGKLGLYFAVVAGGILFHGFVVLSLLFFLFTRNNPLKFIANMGQALATAFGTSSSSATLPVTMQCLEEKNNID 335
Cdd:pfam00375 197 YG--LGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVS 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  336 PRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLVMVLDTVGLPAE 415
Cdd:pfam00375 275 ESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLE 354

                         410       420       430
                  ....*....|....*....|....*....|...
gi 158286949  416 DVSLIIAVDWLLDRFRTLVNVLGDSFGAAIVYH 448
Cdd:pfam00375 355 GIALILAIDRLLDMFRTAVNVTGDAAAAVIVAK 387
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 22-453 1.33e-42

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 156.85  E-value: 1.33e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  22 ILGVIVGIALGLGLRAVPAEGDSWSqrdVTYINYVGDLFLRTLKALILPLIVSSL---IAAVGslDLSLSKKIGGRAVLY 98
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDWLV---SNLLSPAGDIFIHLIKMIVVPIVISTLivgIAGVG--DAKQLGRIGAKTIIY 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  99 YLATTVLAVILGIVLVVTIKPGSDRDGGEADASDAPQRNVTTVD------TLLDLVRNMFPPNlvqactqqyqtvlkppa 172
Cdd:PRK11283  88 FEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEvqshshGLMGTILSLIPTN----------------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 173 skpdetdiyrwtITGAYADGmNILGLVVASIVFGVALG---ATKRENalVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLI 249
Cdd:PRK11283 151 ------------IFASMAKG-EMLPIIFFSVLFGLGLSslpATHREP--LVTVFRSVSETMFKVTHMVMRYAPVGVFALI 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 250 AAKILEiedlgdvFG-----KLGLYFAVVAGGILFHGFVVLSLLFFLFtRNNPLKFIANMGQALATAFGTSSSSATLPVT 324
Cdd:PRK11283 216 AVTVAN-------FGfaslwPLAKLVLLVYFAILFFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLPRI 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 325 MQCLEeKNNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLV 404
Cdd:PRK11283 288 IEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLL 366

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 158286949 405 MVLDTVGLPAEDVSLIIAVDWLLDRFRTLVNVLGDSFGAAIV------YHYSKAE 453
Cdd:PRK11283 367 ATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIakwehkFDRKKAL 421
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 57-438 2.79e-39

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 147.36  E-value: 2.79e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  57 GDLFLRTLKALILPLI---VSSLIAAVGslDLSLSKKIGGRAVLYYLATTVLAVILGIVLVVTIKPGS--DRDGGEADAS 131
Cdd:PRK01663  38 GDGFIKLIKMIIAPIIfctVVTGIAGMG--DMKKVGRVGGKALLYFEIVSTIALIIGLIVVNVVQPGAgmNIDPATLDAK 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 132 D-----APQRNVTTVDTLLDLVrnmfPPNLVqactqqyqtvlkppaskpdetdiyrwtitGAYADGmNILGLVVASIVFG 206
Cdd:PRK01663 116 AvaqyaAQAHEQGTVDFLMDII----PTTVV-----------------------------GAFASG-DILQVLLFAVLFG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 207 VALGATKRENALVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLIAAKI--LEIEDL-------GDVFGKLGLYFAVVAGGI 277
Cdd:PRK01663 162 FALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTIgkYGVGSLvqlgqliGCFYITCILFVFVVLGAI 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 278 L-FHGFvvlsllfflftrnNPLKFIANMGQALATAFGTSSSSATLPVTMQCLEeKNNIDPRVSRFVLPIGATINMDGTAL 356
Cdd:PRK01663 242 ArLTGF-------------SIFKFIRYIKEELLIVLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSI 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 357 YEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLVMVLDTVG-LPAEDVSLIIAVDWLLDRFRTLVN 435
Cdd:PRK01663 308 YLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTN 387


                 ...
gi 158286949 436 VLG 438
Cdd:PRK01663 388 LIG 390
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 22-439 4.09e-39

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 146.74  E-value: 4.09e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  22 ILGVIVGIALGLGLravpaegDSWSQRdvtyINYVGDLFLRTLKALILPLI---VSSLIAAVGslDLSLSKKIGGRAVLY 98
Cdd:PRK13027  13 VIALVLGVALGAFF-------PHFAES----LKPLGDGFIKLIKMLIGPIVfcvVVSGIAGAG--DLKKVGRVGLKAVIY 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  99 YLATTVLAVILGIVLVVTIKPGS--DRDGGEADASDAP------QRNVTTVDTLLDLVRNmfppnlvqactqqyqtvlkp 170
Cdd:PRK13027  80 FEVMTTIALVIGLVLAYLTGPGVgmNIDLRSLDAASLAgyaknaQSLKGTAGFLLKLIPT-------------------- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 171 paskpdetdiyrwTITGAYADGmNILGLVVASIVFGVALGATKRENALVLQFFQQLSHIVMKVTGWVIWLSPVGVTFLIA 250
Cdd:PRK13027 140 -------------TAVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIA 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 251 AK-----ILEIEDLGDV----FGKLGLYFAVVAGGIL-FHGFVVLSLLFFLftrnnplkfianmGQALATAFGTSSSSAT 320
Cdd:PRK13027 206 FTtgkygVGSLKQLGMLvavfYLTCFVFVVVVLGAVMrLAGFSVFKLIRYL-------------REELLIVLGTASSDAV 272

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 321 LPVTMQCLEeKNNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGL 400
Cdd:PRK13027 273 LPQVMRKLE-HMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAI 351

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 158286949 401 VTLVMVLDTVG-LPAEDVSLIIAVDWLLDRFRTLVNVLGD 439
Cdd:PRK13027 352 VILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGN 391
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 17-395 1.09e-21

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 96.86  E-value: 1.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  17 LTTLTILGVIVGIALGLglravpaegdsWSQRDVTYINYVGDLFLRTLKAlILPLIVSSLIAAvgsldlSLS-KKIGGRA 95
Cdd:PRK13628  16 LVKQILIGLVLGILLAL-----------LSPPAAEAVGLLGTLFVGALKA-VAPILVFVLVMA------SIAnHKKGQKT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  96 ------VLYYLAT---TVLAVILGIVLVVTIKPGSdrdggeADASDAPQRNVTTVdtLLDLVRNMFPpNLVQActqqyqt 166
Cdd:PRK13628  78 nirpilVLYLLGTflaALVAVVASFLFPSTLVLVA------SAADISPPQGIVEV--LKTLLLSLVD-NPINA------- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 167 vlkppaskpdetdiyrwTITGayadgmNILGLVVASIVFGVAL----GATKrenalvlQFFQQLSHIVMKVTGWVIWLSP 242
Cdd:PRK13628 142 -----------------LLNA------NYIGILAWAIGLGLALrhasDTTK-------NVVNDLSEAVSQIVKWVIRFAP 191

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 243 VGVTFLIAAKILE--IEDLGDvFGKLglyFAVVAGGILFHGFVVLSLLFFLFTRNN--PLKFIANMGQALaTAFGTSSSS 318
Cdd:PRK13628 192 IGIFGLVASTLAEtgFSALAG-YAQL---LAVLVGCMLFVALVVNPLIVFWKIRRNpyPLVFTCLRESGV-TAFFTRSSA 266

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 158286949 319 ATLPVTMQcLEEKNNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGI 395
Cdd:PRK13628 267 ANIPVNMA-LCEKLGLDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
7-396 3.38e-20

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 92.54  E-value: 3.38e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949   7 SVWGFVRRNLLTTLTILGVIVGIALGLglrAVPAEGDSwsqrdvtyINYVGDLFLRTLKAlILPLIVSSLIAAvgsldlS 86
Cdd:COG3633    5 SLLRKWNRGSLVKQILIGLVLGILLAL---LSPEAAKS--------VGLLGTLFVGALKA-VAPILVFVLVMS------A 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949  87 LS-KKIGGRA------VLYYLAT---TVLAVILGIVLVVTIKPGSdrdggeADASDAPQRNVTTVdtLLDLVRNMFPpNL 156
Cdd:COG3633   67 IAnHKQGQKTnmkpiiVLYLLGTflaALVAVVASFLFPTTLTLVA------AAADLTPPGGIGEV--LKTLLLNVVD-NP 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 157 VQActqqyqtvlkppaskpdetdiyrwtITGAyadgmNILGLVVASIVFGVALgatKRENALVLQFFQQLSHIVMKVTGW 236
Cdd:COG3633  138 VNA-------------------------LANA-----NYIGILAWAIGLGLAL---RHASDTTKTVLSDLSDAVSKIVRW 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 237 VIWLSPVGVTFLIAAKILEiedlgDVFGKLGLYF---AVVAGGILFHGFVVLSLLFFLFTRNNP--LKFIANMGQALaTA 311
Cdd:COG3633  185 VIRFAPLGIFGLVASTVAT-----TGFSALLGYAhllAVLVGCMLFVALVVNPLIVFLKIRRNPypLVFTCLRESGI-TA 258

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 312 FGTSSSSATLPVTMQcLEEKNNIDPRVSRFVLPIGATINMDGTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIG 391
Cdd:COG3633  259 FFTRSSAANIPVNMA-LCEKLGLDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALLLSVVAAVSACG 337


                 ....*
gi 158286949 392 AAGIP 396
Cdd:COG3633  338 ASGVA 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 194-427 1.45e-14

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 74.70  E-value: 1.45e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 194 NILGLVVASIVFGVALGATKRENAlvlQFFQQLSHIVMKVTGWVIWLSPVGVTFLIAaKILEIEDLGDVfGKLGLYFAVV 273
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSL-ANYGILLVLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158286949 274 AGGILFHGFVVLSLLFFLFTRNNPLKFIAN-MGQALATAFGTSSSSATLPVTMQCLEEKNnIDPRVSRFVLPIGATINMD 352
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNcLRVSGVTAFFTRSSATNIPVNMKLCHDLG-LNPDTYSVSIPLGSTINMA 213

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158286949 353 GTALYEAVAAIFIAQLRGLSLSFGNVLAISITATAASIGAAGIPQAGLVTLVMVLDTVGLPAEDVSLIIAVDWLL 427
Cdd:PRK14695 214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVI 288
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH