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Conserved domains on  [gi|1603720756|gb|QBQ71961|]
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exodeoxyribonuclease [Klebsiella phage ST13-OXA48phi12.4]

Protein Classification

exonuclease family protein( domain architecture ID 1004615)

exonuclease family protein with similarity to E. coli exodeoxyribonuclease VIII (EXO VIII) that catalyzes the degradation of double-stranded DNA; acts progressively in a 5' to 3' direction, releasing 5'-phosphomononucleotides

Gene Ontology:  GO:0004527

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK09709 super family cl35886
exodeoxyribonuclease VIII;
25-1034 9.91e-138

exodeoxyribonuclease VIII;


The actual alignment was detected with superfamily member PRK09709:

Pssm-ID: 236615 [Multi-domain]  Cd Length: 877  Bit Score: 436.32  E-value: 9.91e-138
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756   25 YFYLIK---ATQKSGKADAVIWRTNKSEARALLQLDVDLEDAGIETGrgkDYQKPIRTDFPVFNDLPAEGVLDYSWCERY 101
Cdd:PRK09709    10 LYYLRKndkARKRLGEKDGFLWASAKKESTAASRGYLAVDDAGKDES---DFFKPVRVNFPVVNDLPPEGEFDTTFCERY 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  102 QLG-DDGRTWTLKPGQAPA---EHHINDAGVSAEPISGelVDANTTGDAAQGETVETFgsdeyqddssalfnVAELPFRA 177
Cdd:PRK09709    87 ELGsEDGMTWELIPGAASApdnAHYQGNTNVNGEDMTE--IEENMLLPISGQELPIRW--------------LAQHGSEK 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  178 QLLAQYMAEERHVYHISMPHRQELSVLEMDTDNAAVQDLILAAenipeikkydmpaLWKFTSANKKVFPEGKRHELGKRI 257
Cdd:PRK09709   151 PVTHVSRDDLQALHIARAEELPAVTALAVSHKTSLLDPLEIRD-------------LHKLVRDTDKVFPNPGNSNLGLIT 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  258 QFAKLWFATNAIDRGILTREWAAGNCISSVMKTDAGTNAGGGNKTDRNPDYTHTLDTLDVEIALATM--PMDFDIYNFPA 335
Cdd:PRK09709   218 AFFEAYLNADYTDRGLLTKEWMKGNRVSHITRTASGANAGGGNLTDRGEGFVHDLTSLARDVATGVLarSMDLDIYNLHP 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  336 SIHRRAKEIVQKKESPFKEWSAALRKVAGILDYSRAAIFALIRGATSDIHHFPVSLQTYINANLTEHKHDAPSAEMLEKA 415
Cdd:PRK09709   298 AHAKRIEEIIAENKPPFSVFRDKFITMPGGLDYSRAIVVASVKEAPIGIEVIPAHVTEYLNKVLTETDHANPDPEIVDIA 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  416 GHVSSAAV---------------------------TLDAVKKaiDGDEGVPDLEALPTNFQVIGTEL--------VKEAQ 460
Cdd:PRK09709   378 CGRSSAPMpqrvteegkqddeekpqpsgttadeqaTAETVEP--DATEHHQDTQPLDAQSQVNSVDAkyqelraeLHEAR 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  461 KKRPDANQV-----LAAERGEYVEGISDPTDPKWI----TEDLTKPRAPEIANlgggmfsieglmTSPATNATEEGPTSN 531
Cdd:PRK09709   456 KNIPSKNPVdadklLAASRGEFVEGISDPNDPKWVkgiqTRDCVYQNQPETEK------------TSPEMKQPEPVVQQE 523

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  532 VQMEADQSVKNENDNAVSAGEGADEPPAQTTAVNMRKILAERCPDLTAEVLKSQVSENAHSD-----DEEEAEQAAPAWP 606
Cdd:PRK09709   524 PEIVCNACGQTGGDNCPDCGAVMGDATYQETFDEESQVEAKENDPEEMEGAEHPHNENAGSDphrdcSDETGEVADPVIV 603

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  607 EYFEPGRYEGVPNEVYHAANGISSTMVKDARVSLMYFEARHvSKTIQKVRSPVLDMGNLVHALALQPDQLEKEFSIEPEi 686
Cdd:PRK09709   604 EDIEPGIYYGISNENYHAGPGVSKSQLDDIADTPALYLWRK-NAPVDTTKTKTLDLGTAFHCRVLEPEEFSNRFIVAPE- 681

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  687 pegaftttatirafideynnglppllsaddikalleahntilpqpvpmgddvtqtgenymalpaEFQRVEEGQKVTAAKM 766
Cdd:PRK09709   682 ----------------------------------------------------------------FNRRTNAGKEEEKAFL 697

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  767 KACikeynatlpaqvKTTGSrdalleqlALINPDMvaqeaqkaqplkvsGTKADLIQAvksvkpvavfadelldawrenp 846
Cdd:PRK09709   698 MEC------------ASTGK--------TVITAEE--------------GRKIELMYQ---------------------- 721

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  847 egkvlvtrqqlatalaiqkALLNHPTAGKLLTHPSRAVEVSYFGiDEETGLEVRVRPDLEIDMggLRIGADLKTISmwni 926
Cdd:PRK09709   722 -------------------SVMALPLGQWLVESAGHAESSIYWE-DPETGILCRCRPDKIIPE--FHWIMDVKTTA---- 775

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  927 kqegLRAKLHREIIERDYHLSAAMYCET-----AALDQFFWIFVNK--DENYHWIAIIEASEELLELGMLEYRKAMRAIA 999
Cdd:PRK09709   776 ----DIQRFKTAYYDYRYHVQDAFYSDGyeaqfGVQPTFVFLVASTtiECGRYPVEIFMMGEEAKLAGQQEYHRNLRTLA 851

                         1050      1060      1070
                   ....*....|....*....|....*....|....*
gi 1603720756 1000 SGFDTGDWPApitedyteeLNDFDVRRLEALRVQA 1034
Cdd:PRK09709   852 DCLNTDEWPA---------IKTLSLPRWAKEYAND 877
 
Name Accession Description Interval E-value
PRK09709 PRK09709
exodeoxyribonuclease VIII;
25-1034 9.91e-138

exodeoxyribonuclease VIII;


Pssm-ID: 236615 [Multi-domain]  Cd Length: 877  Bit Score: 436.32  E-value: 9.91e-138
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756   25 YFYLIK---ATQKSGKADAVIWRTNKSEARALLQLDVDLEDAGIETGrgkDYQKPIRTDFPVFNDLPAEGVLDYSWCERY 101
Cdd:PRK09709    10 LYYLRKndkARKRLGEKDGFLWASAKKESTAASRGYLAVDDAGKDES---DFFKPVRVNFPVVNDLPPEGEFDTTFCERY 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  102 QLG-DDGRTWTLKPGQAPA---EHHINDAGVSAEPISGelVDANTTGDAAQGETVETFgsdeyqddssalfnVAELPFRA 177
Cdd:PRK09709    87 ELGsEDGMTWELIPGAASApdnAHYQGNTNVNGEDMTE--IEENMLLPISGQELPIRW--------------LAQHGSEK 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  178 QLLAQYMAEERHVYHISMPHRQELSVLEMDTDNAAVQDLILAAenipeikkydmpaLWKFTSANKKVFPEGKRHELGKRI 257
Cdd:PRK09709   151 PVTHVSRDDLQALHIARAEELPAVTALAVSHKTSLLDPLEIRD-------------LHKLVRDTDKVFPNPGNSNLGLIT 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  258 QFAKLWFATNAIDRGILTREWAAGNCISSVMKTDAGTNAGGGNKTDRNPDYTHTLDTLDVEIALATM--PMDFDIYNFPA 335
Cdd:PRK09709   218 AFFEAYLNADYTDRGLLTKEWMKGNRVSHITRTASGANAGGGNLTDRGEGFVHDLTSLARDVATGVLarSMDLDIYNLHP 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  336 SIHRRAKEIVQKKESPFKEWSAALRKVAGILDYSRAAIFALIRGATSDIHHFPVSLQTYINANLTEHKHDAPSAEMLEKA 415
Cdd:PRK09709   298 AHAKRIEEIIAENKPPFSVFRDKFITMPGGLDYSRAIVVASVKEAPIGIEVIPAHVTEYLNKVLTETDHANPDPEIVDIA 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  416 GHVSSAAV---------------------------TLDAVKKaiDGDEGVPDLEALPTNFQVIGTEL--------VKEAQ 460
Cdd:PRK09709   378 CGRSSAPMpqrvteegkqddeekpqpsgttadeqaTAETVEP--DATEHHQDTQPLDAQSQVNSVDAkyqelraeLHEAR 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  461 KKRPDANQV-----LAAERGEYVEGISDPTDPKWI----TEDLTKPRAPEIANlgggmfsieglmTSPATNATEEGPTSN 531
Cdd:PRK09709   456 KNIPSKNPVdadklLAASRGEFVEGISDPNDPKWVkgiqTRDCVYQNQPETEK------------TSPEMKQPEPVVQQE 523

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  532 VQMEADQSVKNENDNAVSAGEGADEPPAQTTAVNMRKILAERCPDLTAEVLKSQVSENAHSD-----DEEEAEQAAPAWP 606
Cdd:PRK09709   524 PEIVCNACGQTGGDNCPDCGAVMGDATYQETFDEESQVEAKENDPEEMEGAEHPHNENAGSDphrdcSDETGEVADPVIV 603

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  607 EYFEPGRYEGVPNEVYHAANGISSTMVKDARVSLMYFEARHvSKTIQKVRSPVLDMGNLVHALALQPDQLEKEFSIEPEi 686
Cdd:PRK09709   604 EDIEPGIYYGISNENYHAGPGVSKSQLDDIADTPALYLWRK-NAPVDTTKTKTLDLGTAFHCRVLEPEEFSNRFIVAPE- 681

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  687 pegaftttatirafideynnglppllsaddikalleahntilpqpvpmgddvtqtgenymalpaEFQRVEEGQKVTAAKM 766
Cdd:PRK09709   682 ----------------------------------------------------------------FNRRTNAGKEEEKAFL 697

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  767 KACikeynatlpaqvKTTGSrdalleqlALINPDMvaqeaqkaqplkvsGTKADLIQAvksvkpvavfadelldawrenp 846
Cdd:PRK09709   698 MEC------------ASTGK--------TVITAEE--------------GRKIELMYQ---------------------- 721

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  847 egkvlvtrqqlatalaiqkALLNHPTAGKLLTHPSRAVEVSYFGiDEETGLEVRVRPDLEIDMggLRIGADLKTISmwni 926
Cdd:PRK09709   722 -------------------SVMALPLGQWLVESAGHAESSIYWE-DPETGILCRCRPDKIIPE--FHWIMDVKTTA---- 775

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  927 kqegLRAKLHREIIERDYHLSAAMYCET-----AALDQFFWIFVNK--DENYHWIAIIEASEELLELGMLEYRKAMRAIA 999
Cdd:PRK09709   776 ----DIQRFKTAYYDYRYHVQDAFYSDGyeaqfGVQPTFVFLVASTtiECGRYPVEIFMMGEEAKLAGQQEYHRNLRTLA 851

                         1050      1060      1070
                   ....*....|....*....|....*....|....*
gi 1603720756 1000 SGFDTGDWPApitedyteeLNDFDVRRLEALRVQA 1034
Cdd:PRK09709   852 DCLNTDEWPA---------IKTLSLPRWAKEYAND 877
Exonuc_VIII pfam06630
Enterobacterial exodeoxyribonuclease VIII; This family consists of several Enterobacterial ...
 26-216 6.14e-36

Enterobacterial exodeoxyribonuclease VIII; This family consists of several Enterobacterial exodeoxyribonuclease VIII proteins.


Pssm-ID: 284130  Cd Length: 203  Bit Score: 135.34  E-value: 6.14e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756   26 FYLIKATQKSGKADAVIWRTNKSEArALLQLDVDLEDAGietGRGKDYQKPIRTDFPVFNDLPAEGVLDYSWCERYQLGD 105
Cdd:pfam06630    6 FLLRKAKKSSGEKDAVLWASDDFEA-ACATLDYLIIKSG---AKLKDYFKAVATNFPVVNDLPAEGEIDFTFCDRYQLAK 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  106 DGRTWTLKPGQ--------APAEHHINDaGVSAEpiSGELVDanttgDAAQGETVETFGSDEYQDDSSALFNVAELPFRA 177
Cdd:pfam06630   82 DNMTWELIPGVtlpsseaaAAANAHIVD-GNDNE--NGEDLE-----DHEENFGNESNSPAQATAPAPELLPIAGMELPH 153

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1603720756  178 QLLAQYMAEERHVYHISMPHRQELSV-----------LEMDTDNAAVQDL 216
Cdd:pfam06630  154 RVLAQHIGEEEPLTHVSRDALQAKEIaraeelpavtaLAMDHDNSLLDNL 203
 
Name Accession Description Interval E-value
PRK09709 PRK09709
exodeoxyribonuclease VIII;
25-1034 9.91e-138

exodeoxyribonuclease VIII;


Pssm-ID: 236615 [Multi-domain]  Cd Length: 877  Bit Score: 436.32  E-value: 9.91e-138
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756   25 YFYLIK---ATQKSGKADAVIWRTNKSEARALLQLDVDLEDAGIETGrgkDYQKPIRTDFPVFNDLPAEGVLDYSWCERY 101
Cdd:PRK09709    10 LYYLRKndkARKRLGEKDGFLWASAKKESTAASRGYLAVDDAGKDES---DFFKPVRVNFPVVNDLPPEGEFDTTFCERY 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  102 QLG-DDGRTWTLKPGQAPA---EHHINDAGVSAEPISGelVDANTTGDAAQGETVETFgsdeyqddssalfnVAELPFRA 177
Cdd:PRK09709    87 ELGsEDGMTWELIPGAASApdnAHYQGNTNVNGEDMTE--IEENMLLPISGQELPIRW--------------LAQHGSEK 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  178 QLLAQYMAEERHVYHISMPHRQELSVLEMDTDNAAVQDLILAAenipeikkydmpaLWKFTSANKKVFPEGKRHELGKRI 257
Cdd:PRK09709   151 PVTHVSRDDLQALHIARAEELPAVTALAVSHKTSLLDPLEIRD-------------LHKLVRDTDKVFPNPGNSNLGLIT 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  258 QFAKLWFATNAIDRGILTREWAAGNCISSVMKTDAGTNAGGGNKTDRNPDYTHTLDTLDVEIALATM--PMDFDIYNFPA 335
Cdd:PRK09709   218 AFFEAYLNADYTDRGLLTKEWMKGNRVSHITRTASGANAGGGNLTDRGEGFVHDLTSLARDVATGVLarSMDLDIYNLHP 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  336 SIHRRAKEIVQKKESPFKEWSAALRKVAGILDYSRAAIFALIRGATSDIHHFPVSLQTYINANLTEHKHDAPSAEMLEKA 415
Cdd:PRK09709   298 AHAKRIEEIIAENKPPFSVFRDKFITMPGGLDYSRAIVVASVKEAPIGIEVIPAHVTEYLNKVLTETDHANPDPEIVDIA 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  416 GHVSSAAV---------------------------TLDAVKKaiDGDEGVPDLEALPTNFQVIGTEL--------VKEAQ 460
Cdd:PRK09709   378 CGRSSAPMpqrvteegkqddeekpqpsgttadeqaTAETVEP--DATEHHQDTQPLDAQSQVNSVDAkyqelraeLHEAR 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  461 KKRPDANQV-----LAAERGEYVEGISDPTDPKWI----TEDLTKPRAPEIANlgggmfsieglmTSPATNATEEGPTSN 531
Cdd:PRK09709   456 KNIPSKNPVdadklLAASRGEFVEGISDPNDPKWVkgiqTRDCVYQNQPETEK------------TSPEMKQPEPVVQQE 523

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  532 VQMEADQSVKNENDNAVSAGEGADEPPAQTTAVNMRKILAERCPDLTAEVLKSQVSENAHSD-----DEEEAEQAAPAWP 606
Cdd:PRK09709   524 PEIVCNACGQTGGDNCPDCGAVMGDATYQETFDEESQVEAKENDPEEMEGAEHPHNENAGSDphrdcSDETGEVADPVIV 603

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  607 EYFEPGRYEGVPNEVYHAANGISSTMVKDARVSLMYFEARHvSKTIQKVRSPVLDMGNLVHALALQPDQLEKEFSIEPEi 686
Cdd:PRK09709   604 EDIEPGIYYGISNENYHAGPGVSKSQLDDIADTPALYLWRK-NAPVDTTKTKTLDLGTAFHCRVLEPEEFSNRFIVAPE- 681

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  687 pegaftttatirafideynnglppllsaddikalleahntilpqpvpmgddvtqtgenymalpaEFQRVEEGQKVTAAKM 766
Cdd:PRK09709   682 ----------------------------------------------------------------FNRRTNAGKEEEKAFL 697

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  767 KACikeynatlpaqvKTTGSrdalleqlALINPDMvaqeaqkaqplkvsGTKADLIQAvksvkpvavfadelldawrenp 846
Cdd:PRK09709   698 MEC------------ASTGK--------TVITAEE--------------GRKIELMYQ---------------------- 721

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  847 egkvlvtrqqlatalaiqkALLNHPTAGKLLTHPSRAVEVSYFGiDEETGLEVRVRPDLEIDMggLRIGADLKTISmwni 926
Cdd:PRK09709   722 -------------------SVMALPLGQWLVESAGHAESSIYWE-DPETGILCRCRPDKIIPE--FHWIMDVKTTA---- 775

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  927 kqegLRAKLHREIIERDYHLSAAMYCET-----AALDQFFWIFVNK--DENYHWIAIIEASEELLELGMLEYRKAMRAIA 999
Cdd:PRK09709   776 ----DIQRFKTAYYDYRYHVQDAFYSDGyeaqfGVQPTFVFLVASTtiECGRYPVEIFMMGEEAKLAGQQEYHRNLRTLA 851

                         1050      1060      1070
                   ....*....|....*....|....*....|....*
gi 1603720756 1000 SGFDTGDWPApitedyteeLNDFDVRRLEALRVQA 1034
Cdd:PRK09709   852 DCLNTDEWPA---------IKTLSLPRWAKEYAND 877
Exonuc_VIII pfam06630
Enterobacterial exodeoxyribonuclease VIII; This family consists of several Enterobacterial ...
 26-216 6.14e-36

Enterobacterial exodeoxyribonuclease VIII; This family consists of several Enterobacterial exodeoxyribonuclease VIII proteins.


Pssm-ID: 284130  Cd Length: 203  Bit Score: 135.34  E-value: 6.14e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756   26 FYLIKATQKSGKADAVIWRTNKSEArALLQLDVDLEDAGietGRGKDYQKPIRTDFPVFNDLPAEGVLDYSWCERYQLGD 105
Cdd:pfam06630    6 FLLRKAKKSSGEKDAVLWASDDFEA-ACATLDYLIIKSG---AKLKDYFKAVATNFPVVNDLPAEGEIDFTFCDRYQLAK 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  106 DGRTWTLKPGQ--------APAEHHINDaGVSAEpiSGELVDanttgDAAQGETVETFGSDEYQDDSSALFNVAELPFRA 177
Cdd:pfam06630   82 DNMTWELIPGVtlpsseaaAAANAHIVD-GNDNE--NGEDLE-----DHEENFGNESNSPAQATAPAPELLPIAGMELPH 153

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1603720756  178 QLLAQYMAEERHVYHISMPHRQELSV-----------LEMDTDNAAVQDL 216
Cdd:pfam06630  154 RVLAQHIGEEEPLTHVSRDALQAKEIaraeelpavtaLAMDHDNSLLDNL 203
DUF3799 pfam12684
PDDEXK-like domain of unknown function (DUF3799); This family of proteins is functionally ...
 854-980 5.02e-05

PDDEXK-like domain of unknown function (DUF3799); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 265 and 420 amino acids in length. It appears that these proteins are distantly related to the PDDEXK superfamily and so these domains are likely to be nucleases. This family has a C-terminal cysteine cluster similar to that found in pfam01930.


Pssm-ID: 432717 [Multi-domain]  Cd Length: 231  Bit Score: 45.76  E-value: 5.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1603720756  854 RQQLATALAIQKALLNHPTAGKLLthpSRAVEVSYFGidEETGLEVRVRPDLEIDMGGLrigADLKTISmwNIKQEGLRA 933
Cdd:pfam12684   69 KAEFQIANQMIERLKNDPLFMKLY---SGEKEVIFTG--ELFGVPWKIKIDSLNPEGYF---VDLKTTR--DIHKRKWNE 138

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1603720756  934 KLHRE--IIERDYHLSAAMYCE-----TAALDQFFWIFVNKdENYHWIAIIEAS 980
Cdd:pfam12684  139 DAGRRvtIEAYGYDLQMAVYQEglrqnTGKTLPPYIIAVEK-ETPPDKAIITAG 191
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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