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Conserved domains on  [gi|1709091|sp|Q07113|]
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RecName: Full=Cation-independent mannose-6-phosphate receptor; Short=CI Man-6-P receptor; Short=CI-MPR; Short=M6PR; AltName: Full=300 kDa mannose 6-phosphate receptor; Short=MPR 300; AltName: Full=Insulin-like growth factor 2 receptor; AltName: Full=Insulin-like growth factor II receptor; Short=IGF-II receptor; AltName: Full=M6P/IGF2 receptor; Short=M6P/IGF2R; AltName: CD_antigen=CD222; Flags: Precursor

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1024-1171 2.08e-69

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 230.08  E-value: 2.08e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1024 DRGTAFIIRFICNDDIYPGAPKFLHQDIdstrGIRNTYFEFETALACT-PSLVDCQVTDPAGNEYDLSALSMVRKPWTAV 1102
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1709091    1103 DTSAYGKRRHFYLSVCNPLPYIPGCHgIALGSCMVSEDNSFNLGVVQISPQATgNGSLSILYVNGDRCG 1171
Cdd:pfam00878   77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQKT-NGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1315-1455 3.56e-67

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 223.53  E-value: 3.56e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1315 VYQRSTTIYFYCDRTT--QKPVFLKETS-DCSYMFEWRTQYACPPFNVTECSVQDAAGNSIDLSSLSRYSDNWEAVTRTG 1391
Cdd:pfam00878    1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709091    1392 A--TEHYLINVCKslsPHAGTEPCPPEAAVCLLNGSKPVNLGKVRDGPQWTDGVTVLQYVDGDLCP 1455
Cdd:pfam00878   81 DgkKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
418-567 4.93e-55

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 188.86  E-value: 4.93e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     418 GFQRMSVINFECNKTAGKDgrgEPVFTGEV--DCTYFFTWDTKYACIKeKEDLLCGAINGK-KRYDLSVLARHSEseqNW 494
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNG---APVFLHEDigDCSYFFEWETAYACVK-PEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1709091     495 EAVDGSQAESEKYFFINVCHrvlQEGKARNCPEDAAVCAVDKNGSKNLGKFVSSPTKEKGHIQLSYTDGDDCG 567
Cdd:pfam00878   74 EAVDTSGDGKKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
569-709 4.07e-51

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 177.69  E-value: 4.07e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     569 DKKISTNITLVCKPGDLESAPVLRAARSDGCFYEFEWHTAAACVlsKTEGENCTVLDAqAGFSFDLSLLTKKNGAYKVET 648
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACV--KPEDVDCQVTDA-AGNEYDLSSLSRYSKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709091     649 EKYD-----FYINVCGP-VSMDPCQSNSGACQVAKsGKSWNLGLSSTKLTYYDGMIQLSYRNGTPYN 709
Cdd:pfam00878   78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDK-GKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
716-868 2.29e-27

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 109.51  E-value: 2.29e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     716 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECMVTDPSMmEQYDLSSLVKSEGgsggNWYAMEN 792
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709091     793 SREHVTRRkYYLNVCRPLNPVPGCDRYASACQmkyenhegsLAETVSIsNLGVAKIGPVVEEsGSLLLEYVNGSAC 868
Cdd:pfam00878   79 SGDGKKRH-FYINVCHPLPGIPGCPSAAGVCL---------VDKGKSW-NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
FN2 cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ...
1890-1935 7.40e-19

Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.


:

Pssm-ID: 238019  Cd Length: 48  Bit Score: 81.97  E-value: 7.40e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1709091  1890 TDDGEPCVFPFIYKGKSYDECVLEGRA--KLWCSKTANYDRDHEWGFC 1935
Cdd:cd00062    1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1752-1887 4.46e-17

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 80.23  E-value: 4.46e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1752 TSLITFHCKRGVSMGTPKLIR--TNDCDFVFEWETPIVCpdeVKTQG--CAVTDEQlLYSFNLTSLSTS-------TFKV 1820
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYAC---VKPEDvdCQVTDAA-GNEYDLSSLSRYsknweavDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709091    1821 TRDARTYSIGVCTAAAGLgqEGCK-DGGVCLLSGNKGASFGRLasmQLDYRHQDEAVILSYVNGDPCP 1887
Cdd:pfam00878   81 DGKKRHFYINVCHPLPGI--PGCPsAAGVCLVDKGKSWNLGVV---QSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1459-1592 9.87e-17

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 79.08  E-value: 9.87e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1459 RRRSTIIRFTCSDNQVNSRPLFISAV-QDCEYTFSWPTPSACPVKSNThdDCQVTNPStGHLFDLSSLSGRAG----INA 1533
Cdd:pfam00878    2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweaVDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1709091    1534 SYSEKGLVF-MSICEEN---ENCGPGVGACF--GQTRISVGKASKRLSYKDQVLQLVYENGSPCP 1592
Cdd:pfam00878   79 SGDGKKRHFyINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1601-1724 1.29e-15

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 76.00  E-value: 1.29e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1601 SVISFVCRPEAGPtNRPMLISLDKQTCTLFFSWHTPLAC--EQATECTVRNGSSI-IDLSPLIHRTGGYEAYDESEDDTS 1677
Cdd:pfam00878    6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACvkPEDVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1709091    1678 DTtpdFYINICQPLNPMHGvpCPAGASVCKVPVDGpPIDIGRVTGPP 1724
Cdd:pfam00878   85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
121-260 1.72e-12

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 67.14  E-value: 1.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     121 IQTSITFLCGKTL--GTPEFVTAT--DCVHYFEWRTTAACKKdifkaDKEVPCYAFDDKLQKHDLNPLIKLNGGYLVDDS 196
Cdd:pfam00878    4 RATIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709091     197 DPDTS---LFINVCRdidslrdPSTQLRVCPAGTAACLLKGNQAFDVGRPKEGLKlLSKDRLVLTYV 260
Cdd:pfam00878   79 SGDGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYV 137
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1942-2076 3.46e-11

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 63.28  E-value: 3.46e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1942 RMSAIIFTCDESEDIGRPQVFSEDRG-CEVTFEWKTKVVCPPKK-MECKFV-QKHKTYDLRLLSSLTGSWDFV-----HE 2013
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVdtsgdGK 83
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1709091    2014 GNSYFINLCQRVYKGPLdCSERASICKKSATGQVQvLGLVHTqKLEVIDETVIVTYSKGYPCG 2076
Cdd:pfam00878   84 KRHFYINVCHPLPGIPG-CPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2234-2273 1.64e-05

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 47.11  E-value: 1.64e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1709091    2234 SSTIFFHCDPLVKDGIPEFSHET-ADCQYLFSWYTSAVCPL 2273
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVK 45
ATG27 super family cl39051
Autophagy-related protein 27;
323-467 5.15e-05

Autophagy-related protein 27;


The actual alignment was detected with superfamily member pfam09451:

Pssm-ID: 476860  Cd Length: 261  Bit Score: 47.33  E-value: 5.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     323 CSLSSEQHdiTIDLSPLAqygGSPYVSDGRE-------YTFFINVCGD-------TKVSLCNNKeAAVCQ------EKKA 382
Cdd:pfam09451   19 CSVDKGLK--KYDLSKLK---GPHSVSTTRDtppsttnTTWTINICEPlkkdkdvDKPDQCPKG-TRVCGitrvilDGDD 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     383 DSTQV-KIAGRHQNQT---LRYSDGD--LTLIYSGGDecSSGFQRMSVINFECNKTAGKDGRGEPvftGEVDCTYFFTWD 456
Cdd:pfam09451   93 RITQViPIGGSNLDPEvtrLKTSDEKegLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVSYDG---SQEDDKLRLEWK 167
                          170
                   ....*....|.
gi 1709091     457 TKYACIKEKED 467
Cdd:pfam09451  168 TKYACEKDESD 178
ATG27 super family cl39051
Autophagy-related protein 27;
1219-1355 3.00e-04

Autophagy-related protein 27;


The actual alignment was detected with superfamily member pfam09451:

Pssm-ID: 476860  Cd Length: 261  Bit Score: 45.02  E-value: 3.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1219 NCQVKDprHGNLYDLKPLG-------LNDTIVSVGEYTYYLRVCGKLSSDvcsahDGSKAVSSCQE-----------KKG 1280
Cdd:pfam09451   18 DCSVDK--GLKKYDLSKLKgphsvstTRDTPPSTTNTTWTINICEPLKKD-----KDVDKPDQCPKgtrvcgitrviLDG 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1281 PQGFQKVAGLLSQKLTFE---------NGLLKMNYTGGDtcHKVYQRSTTIYFYCDRTTQKPV-FLKETSDCSYMFEWRT 1350
Cdd:pfam09451   91 DDRITQVIPIGGSNLDPEvtrlktsdeKEGLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVsYDGSQEDDKLRLEWKT 168

                   ....*
gi 1709091    1351 QYACP 1355
Cdd:pfam09451  169 KYACE 173
 
Name Accession Description Interval E-value
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1024-1171 2.08e-69

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 230.08  E-value: 2.08e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1024 DRGTAFIIRFICNDDIYPGAPKFLHQDIdstrGIRNTYFEFETALACT-PSLVDCQVTDPAGNEYDLSALSMVRKPWTAV 1102
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1709091    1103 DTSAYGKRRHFYLSVCNPLPYIPGCHgIALGSCMVSEDNSFNLGVVQISPQATgNGSLSILYVNGDRCG 1171
Cdd:pfam00878   77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQKT-NGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1315-1455 3.56e-67

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 223.53  E-value: 3.56e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1315 VYQRSTTIYFYCDRTT--QKPVFLKETS-DCSYMFEWRTQYACPPFNVTECSVQDAAGNSIDLSSLSRYSDNWEAVTRTG 1391
Cdd:pfam00878    1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709091    1392 A--TEHYLINVCKslsPHAGTEPCPPEAAVCLLNGSKPVNLGKVRDGPQWTDGVTVLQYVDGDLCP 1455
Cdd:pfam00878   81 DgkKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
418-567 4.93e-55

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 188.86  E-value: 4.93e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     418 GFQRMSVINFECNKTAGKDgrgEPVFTGEV--DCTYFFTWDTKYACIKeKEDLLCGAINGK-KRYDLSVLARHSEseqNW 494
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNG---APVFLHEDigDCSYFFEWETAYACVK-PEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1709091     495 EAVDGSQAESEKYFFINVCHrvlQEGKARNCPEDAAVCAVDKNGSKNLGKFVSSPTKEKGHIQLSYTDGDDCG 567
Cdd:pfam00878   74 EAVDTSGDGKKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
569-709 4.07e-51

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 177.69  E-value: 4.07e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     569 DKKISTNITLVCKPGDLESAPVLRAARSDGCFYEFEWHTAAACVlsKTEGENCTVLDAqAGFSFDLSLLTKKNGAYKVET 648
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACV--KPEDVDCQVTDA-AGNEYDLSSLSRYSKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709091     649 EKYD-----FYINVCGP-VSMDPCQSNSGACQVAKsGKSWNLGLSSTKLTYYDGMIQLSYRNGTPYN 709
Cdd:pfam00878   78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDK-GKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
716-868 2.29e-27

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 109.51  E-value: 2.29e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     716 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECMVTDPSMmEQYDLSSLVKSEGgsggNWYAMEN 792
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709091     793 SREHVTRRkYYLNVCRPLNPVPGCDRYASACQmkyenhegsLAETVSIsNLGVAKIGPVVEEsGSLLLEYVNGSAC 868
Cdd:pfam00878   79 SGDGKKRH-FYINVCHPLPGIPGCPSAAGVCL---------VDKGKSW-NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
FN2 cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ...
1890-1935 7.40e-19

Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.


Pssm-ID: 238019  Cd Length: 48  Bit Score: 81.97  E-value: 7.40e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1709091  1890 TDDGEPCVFPFIYKGKSYDECVLEGRA--KLWCSKTANYDRDHEWGFC 1935
Cdd:cd00062    1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
FN2 smart00059
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ...
1892-1935 9.62e-19

Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function.


Pssm-ID: 128373  Cd Length: 49  Bit Score: 81.58  E-value: 9.62e-19
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1709091     1892 DGEPCVFPFIYKGKSYDECVLEGRA--KLWCSKTANYDRDHEWGFC 1935
Cdd:smart00059    4 DGEPCVFPFIYNGKKYHDCTSEGRSdgMLWCSTTPNYDRDGKWGFC 49
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1752-1887 4.46e-17

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 80.23  E-value: 4.46e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1752 TSLITFHCKRGVSMGTPKLIR--TNDCDFVFEWETPIVCpdeVKTQG--CAVTDEQlLYSFNLTSLSTS-------TFKV 1820
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYAC---VKPEDvdCQVTDAA-GNEYDLSSLSRYsknweavDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709091    1821 TRDARTYSIGVCTAAAGLgqEGCK-DGGVCLLSGNKGASFGRLasmQLDYRHQDEAVILSYVNGDPCP 1887
Cdd:pfam00878   81 DGKKRHFYINVCHPLPGI--PGCPsAAGVCLVDKGKSWNLGVV---QSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1459-1592 9.87e-17

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 79.08  E-value: 9.87e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1459 RRRSTIIRFTCSDNQVNSRPLFISAV-QDCEYTFSWPTPSACPVKSNThdDCQVTNPStGHLFDLSSLSGRAG----INA 1533
Cdd:pfam00878    2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweaVDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1709091    1534 SYSEKGLVF-MSICEEN---ENCGPGVGACF--GQTRISVGKASKRLSYKDQVLQLVYENGSPCP 1592
Cdd:pfam00878   79 SGDGKKRHFyINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
fn2 pfam00040
Fibronectin type II domain;
1896-1935 4.10e-16

Fibronectin type II domain;


Pssm-ID: 459645  Cd Length: 42  Bit Score: 73.76  E-value: 4.10e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1709091    1896 CVFPFIYKGKSYDECVLEGRA--KLWCSKTANYDRDHEWGFC 1935
Cdd:pfam00040    1 CVFPFKYKGKWYHTCTTDGRRsgRLWCATTANYDGDGKWGYC 42
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1601-1724 1.29e-15

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 76.00  E-value: 1.29e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1601 SVISFVCRPEAGPtNRPMLISLDKQTCTLFFSWHTPLAC--EQATECTVRNGSSI-IDLSPLIHRTGGYEAYDESEDDTS 1677
Cdd:pfam00878    6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACvkPEDVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1709091    1678 DTtpdFYINICQPLNPMHGvpCPAGASVCKVPVDGpPIDIGRVTGPP 1724
Cdd:pfam00878   85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
121-260 1.72e-12

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 67.14  E-value: 1.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     121 IQTSITFLCGKTL--GTPEFVTAT--DCVHYFEWRTTAACKKdifkaDKEVPCYAFDDKLQKHDLNPLIKLNGGYLVDDS 196
Cdd:pfam00878    4 RATIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709091     197 DPDTS---LFINVCRdidslrdPSTQLRVCPAGTAACLLKGNQAFDVGRPKEGLKlLSKDRLVLTYV 260
Cdd:pfam00878   79 SGDGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYV 137
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1942-2076 3.46e-11

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 63.28  E-value: 3.46e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1942 RMSAIIFTCDESEDIGRPQVFSEDRG-CEVTFEWKTKVVCPPKK-MECKFV-QKHKTYDLRLLSSLTGSWDFV-----HE 2013
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVdtsgdGK 83
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1709091    2014 GNSYFINLCQRVYKGPLdCSERASICKKSATGQVQvLGLVHTqKLEVIDETVIVTYSKGYPCG 2076
Cdd:pfam00878   84 KRHFYINVCHPLPGIPG-CPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2234-2273 1.64e-05

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 47.11  E-value: 1.64e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1709091    2234 SSTIFFHCDPLVKDGIPEFSHET-ADCQYLFSWYTSAVCPL 2273
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVK 45
ATG27 pfam09451
Autophagy-related protein 27;
323-467 5.15e-05

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 47.33  E-value: 5.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     323 CSLSSEQHdiTIDLSPLAqygGSPYVSDGRE-------YTFFINVCGD-------TKVSLCNNKeAAVCQ------EKKA 382
Cdd:pfam09451   19 CSVDKGLK--KYDLSKLK---GPHSVSTTRDtppsttnTTWTINICEPlkkdkdvDKPDQCPKG-TRVCGitrvilDGDD 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     383 DSTQV-KIAGRHQNQT---LRYSDGD--LTLIYSGGDecSSGFQRMSVINFECNKTAGKDGRGEPvftGEVDCTYFFTWD 456
Cdd:pfam09451   93 RITQViPIGGSNLDPEvtrLKTSDEKegLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVSYDG---SQEDDKLRLEWK 167
                          170
                   ....*....|.
gi 1709091     457 TKYACIKEKED 467
Cdd:pfam09451  168 TKYACEKDESD 178
ATG27 pfam09451
Autophagy-related protein 27;
1219-1355 3.00e-04

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 45.02  E-value: 3.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1219 NCQVKDprHGNLYDLKPLG-------LNDTIVSVGEYTYYLRVCGKLSSDvcsahDGSKAVSSCQE-----------KKG 1280
Cdd:pfam09451   18 DCSVDK--GLKKYDLSKLKgphsvstTRDTPPSTTNTTWTINICEPLKKD-----KDVDKPDQCPKgtrvcgitrviLDG 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1281 PQGFQKVAGLLSQKLTFE---------NGLLKMNYTGGDtcHKVYQRSTTIYFYCDRTTQKPV-FLKETSDCSYMFEWRT 1350
Cdd:pfam09451   91 DDRITQVIPIGGSNLDPEvtrlktsdeKEGLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVsYDGSQEDDKLRLEWKT 168

                   ....*
gi 1709091    1351 QYACP 1355
Cdd:pfam09451  169 KYACE 173
 
Name Accession Description Interval E-value
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1024-1171 2.08e-69

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 230.08  E-value: 2.08e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1024 DRGTAFIIRFICNDDIYPGAPKFLHQDIdstrGIRNTYFEFETALACT-PSLVDCQVTDPAGNEYDLSALSMVRKPWTAV 1102
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1709091    1103 DTSAYGKRRHFYLSVCNPLPYIPGCHgIALGSCMVSEDNSFNLGVVQISPQATgNGSLSILYVNGDRCG 1171
Cdd:pfam00878   77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQKT-NGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1315-1455 3.56e-67

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 223.53  E-value: 3.56e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1315 VYQRSTTIYFYCDRTT--QKPVFLKETS-DCSYMFEWRTQYACPPFNVTECSVQDAAGNSIDLSSLSRYSDNWEAVTRTG 1391
Cdd:pfam00878    1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709091    1392 A--TEHYLINVCKslsPHAGTEPCPPEAAVCLLNGSKPVNLGKVRDGPQWTDGVTVLQYVDGDLCP 1455
Cdd:pfam00878   81 DgkKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
418-567 4.93e-55

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 188.86  E-value: 4.93e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     418 GFQRMSVINFECNKTAGKDgrgEPVFTGEV--DCTYFFTWDTKYACIKeKEDLLCGAINGK-KRYDLSVLARHSEseqNW 494
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNG---APVFLHEDigDCSYFFEWETAYACVK-PEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1709091     495 EAVDGSQAESEKYFFINVCHrvlQEGKARNCPEDAAVCAVDKNGSKNLGKFVSSPTKEKGHIQLSYTDGDDCG 567
Cdd:pfam00878   74 EAVDTSGDGKKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
569-709 4.07e-51

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 177.69  E-value: 4.07e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     569 DKKISTNITLVCKPGDLESAPVLRAARSDGCFYEFEWHTAAACVlsKTEGENCTVLDAqAGFSFDLSLLTKKNGAYKVET 648
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACV--KPEDVDCQVTDA-AGNEYDLSSLSRYSKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709091     649 EKYD-----FYINVCGP-VSMDPCQSNSGACQVAKsGKSWNLGLSSTKLTYYDGMIQLSYRNGTPYN 709
Cdd:pfam00878   78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDK-GKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
716-868 2.29e-27

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 109.51  E-value: 2.29e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     716 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECMVTDPSMmEQYDLSSLVKSEGgsggNWYAMEN 792
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709091     793 SREHVTRRkYYLNVCRPLNPVPGCDRYASACQmkyenhegsLAETVSIsNLGVAKIGPVVEEsGSLLLEYVNGSAC 868
Cdd:pfam00878   79 SGDGKKRH-FYINVCHPLPGIPGCPSAAGVCL---------VDKGKSW-NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
FN2 cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ...
1890-1935 7.40e-19

Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.


Pssm-ID: 238019  Cd Length: 48  Bit Score: 81.97  E-value: 7.40e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1709091  1890 TDDGEPCVFPFIYKGKSYDECVLEGRA--KLWCSKTANYDRDHEWGFC 1935
Cdd:cd00062    1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
FN2 smart00059
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ...
1892-1935 9.62e-19

Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function.


Pssm-ID: 128373  Cd Length: 49  Bit Score: 81.58  E-value: 9.62e-19
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1709091     1892 DGEPCVFPFIYKGKSYDECVLEGRA--KLWCSKTANYDRDHEWGFC 1935
Cdd:smart00059    4 DGEPCVFPFIYNGKKYHDCTSEGRSdgMLWCSTTPNYDRDGKWGFC 49
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1752-1887 4.46e-17

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 80.23  E-value: 4.46e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1752 TSLITFHCKRGVSMGTPKLIR--TNDCDFVFEWETPIVCpdeVKTQG--CAVTDEQlLYSFNLTSLSTS-------TFKV 1820
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYAC---VKPEDvdCQVTDAA-GNEYDLSSLSRYsknweavDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709091    1821 TRDARTYSIGVCTAAAGLgqEGCK-DGGVCLLSGNKGASFGRLasmQLDYRHQDEAVILSYVNGDPCP 1887
Cdd:pfam00878   81 DGKKRHFYINVCHPLPGI--PGCPsAAGVCLVDKGKSWNLGVV---QSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1459-1592 9.87e-17

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 79.08  E-value: 9.87e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1459 RRRSTIIRFTCSDNQVNSRPLFISAV-QDCEYTFSWPTPSACPVKSNThdDCQVTNPStGHLFDLSSLSGRAG----INA 1533
Cdd:pfam00878    2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweaVDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1709091    1534 SYSEKGLVF-MSICEEN---ENCGPGVGACF--GQTRISVGKASKRLSYKDQVLQLVYENGSPCP 1592
Cdd:pfam00878   79 SGDGKKRHFyINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
fn2 pfam00040
Fibronectin type II domain;
1896-1935 4.10e-16

Fibronectin type II domain;


Pssm-ID: 459645  Cd Length: 42  Bit Score: 73.76  E-value: 4.10e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1709091    1896 CVFPFIYKGKSYDECVLEGRA--KLWCSKTANYDRDHEWGFC 1935
Cdd:pfam00040    1 CVFPFKYKGKWYHTCTTDGRRsgRLWCATTANYDGDGKWGYC 42
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1601-1724 1.29e-15

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 76.00  E-value: 1.29e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1601 SVISFVCRPEAGPtNRPMLISLDKQTCTLFFSWHTPLAC--EQATECTVRNGSSI-IDLSPLIHRTGGYEAYDESEDDTS 1677
Cdd:pfam00878    6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACvkPEDVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1709091    1678 DTtpdFYINICQPLNPMHGvpCPAGASVCKVPVDGpPIDIGRVTGPP 1724
Cdd:pfam00878   85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
121-260 1.72e-12

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 67.14  E-value: 1.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     121 IQTSITFLCGKTL--GTPEFVTAT--DCVHYFEWRTTAACKKdifkaDKEVPCYAFDDKLQKHDLNPLIKLNGGYLVDDS 196
Cdd:pfam00878    4 RATIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709091     197 DPDTS---LFINVCRdidslrdPSTQLRVCPAGTAACLLKGNQAFDVGRPKEGLKlLSKDRLVLTYV 260
Cdd:pfam00878   79 SGDGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYV 137
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1942-2076 3.46e-11

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 63.28  E-value: 3.46e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1942 RMSAIIFTCDESEDIGRPQVFSEDRG-CEVTFEWKTKVVCPPKK-MECKFV-QKHKTYDLRLLSSLTGSWDFV-----HE 2013
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVdtsgdGK 83
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1709091    2014 GNSYFINLCQRVYKGPLdCSERASICKKSATGQVQvLGLVHTqKLEVIDETVIVTYSKGYPCG 2076
Cdd:pfam00878   84 KRHFYINVCHPLPGIPG-CPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2234-2273 1.64e-05

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 47.11  E-value: 1.64e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1709091    2234 SSTIFFHCDPLVKDGIPEFSHET-ADCQYLFSWYTSAVCPL 2273
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVK 45
ATG27 pfam09451
Autophagy-related protein 27;
1627-1708 2.35e-05

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 48.48  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1627 CTLFFSWHTPLACEQATECTVRNGSSIIDLSPLihrTGGYEAYDESEDDTSDTTPDFYINICQPLNPMHGVP----CPAG 1702
Cdd:pfam09451    1 LLLLLPLLAAASAVSAFDCSVDKGLKKYDLSKL---KGPHSVSTTRDTPPSTTNTTWTINICEPLKKDKDVDkpdqCPKG 77

                   ....*.
gi 1709091    1703 ASVCKV 1708
Cdd:pfam09451   78 TRVCGI 83
ATG27 pfam09451
Autophagy-related protein 27;
323-467 5.15e-05

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 47.33  E-value: 5.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     323 CSLSSEQHdiTIDLSPLAqygGSPYVSDGRE-------YTFFINVCGD-------TKVSLCNNKeAAVCQ------EKKA 382
Cdd:pfam09451   19 CSVDKGLK--KYDLSKLK---GPHSVSTTRDtppsttnTTWTINICEPlkkdkdvDKPDQCPKG-TRVCGitrvilDGDD 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     383 DSTQV-KIAGRHQNQT---LRYSDGD--LTLIYSGGDecSSGFQRMSVINFECNKTAGKDGRGEPvftGEVDCTYFFTWD 456
Cdd:pfam09451   93 RITQViPIGGSNLDPEvtrLKTSDEKegLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVSYDG---SQEDDKLRLEWK 167
                          170
                   ....*....|.
gi 1709091     457 TKYACIKEKED 467
Cdd:pfam09451  168 TKYACEKDESD 178
ATG27 pfam09451
Autophagy-related protein 27;
607-754 5.84e-05

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 47.33  E-value: 5.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     607 TAAACVLSKTEGENCTVldAQAGFSFDLSLLtkkNGAYKVETEKYD--------FYINVCGPVSMDP-------CQSNSG 671
Cdd:pfam09451    5 LPLLAAASAVSAFDCSV--DKGLKKYDLSKL---KGPHSVSTTRDTppsttnttWTINICEPLKKDKdvdkpdqCPKGTR 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     672 ACQVAK---------------SGKSWNLGLSSTKLTYYDGMIQLSYRNGTpynnEKHTPRATLITFLCDRDAgVGFPEYQ 736
Cdd:pfam09451   80 VCGITRvildgddritqvipiGGSNLDPEVTRLKTSDEKEGLRLTLKGGK----WGGNKQDAIIEFICDSDS-LTFVSYD 154
                          170
                   ....*....|....*....
gi 1709091     737 -EEDNSTYNFRWYTSYACP 754
Cdd:pfam09451  155 gSQEDDKLRLEWKTKYACE 173
ATG27 pfam09451
Autophagy-related protein 27;
1219-1355 3.00e-04

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 45.02  E-value: 3.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1219 NCQVKDprHGNLYDLKPLG-------LNDTIVSVGEYTYYLRVCGKLSSDvcsahDGSKAVSSCQE-----------KKG 1280
Cdd:pfam09451   18 DCSVDK--GLKKYDLSKLKgphsvstTRDTPPSTTNTTWTINICEPLKKD-----KDVDKPDQCPKgtrvcgitrviLDG 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1281 PQGFQKVAGLLSQKLTFE---------NGLLKMNYTGGDtcHKVYQRSTTIYFYCDRTTQKPV-FLKETSDCSYMFEWRT 1350
Cdd:pfam09451   91 DDRITQVIPIGGSNLDPEvtrlktsdeKEGLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVsYDGSQEDDKLRLEWKT 168

                   ....*
gi 1709091    1351 QYACP 1355
Cdd:pfam09451  169 KYACE 173
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
645-757 3.63e-04

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 44.77  E-value: 3.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     645 KVETEKYDFYINVCGPVSMDPcqSNSGACQVAKS-GKSWNLG-LSSTKLTYYDGMIQLSYRNGTPYNNEKHT-PRATLIT 721
Cdd:pfam02157   42 GSGPETYTYNFRVCREVGKTA--SDAGLVQIDKKnGKETVIGrINETQVFNGSDWIMLIYKGGDEYGSHCGKeKRKAIIM 119
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1709091     722 FLCDRDAGVG-----FPEYQEEDNSTYNFRWYTSYACPEEP 757
Cdd:pfam02157  120 ISCNRKVLADnftivIEEREKEQDCFYLFELDSSLACPPED 160
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
1210-1356 7.31e-04

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 44.00  E-value: 7.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1210 CPVIREEGDNCQVKDPRHGNLYDLKPLGLNDTI-VSVGEYTYYLRVCGKLSSdvcSAHDGSKAvsscQEKKGPQGfQKVA 1288
Cdd:pfam02157    9 CDLVGEESSESQKERALLKRLEPLANKSFEVTVgSGPETYTYNFRVCREVGK---TASDAGLV----QIDKKNGK-ETVI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1289 GLLSQKLTFeNGL--LKMNYTGGDT----CHKvYQRSTTIYFYCDRTTQKPVF-------LKETsDCSYMFEWRTQYACP 1355
Cdd:pfam02157   81 GRINETQVF-NGSdwIMLIYKGGDEygshCGK-EKRKAIIMISCNRKVLADNFtivieerEKEQ-DCFYLFELDSSLACP 157

                   .
gi 1709091    1356 P 1356
Cdd:pfam02157  158 P 158
ATG27 pfam09451
Autophagy-related protein 27;
470-611 1.37e-03

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 43.09  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     470 CGAINGKKRYDLSVLARHSESEQNWEAVDGSQAESekyFFINVCHRVLQEG---KARNCPEDAAVCAVDKN--------- 537
Cdd:pfam09451   19 CSVDKGLKKYDLSKLKGPHSVSTTRDTPPSTTNTT---WTINICEPLKKDKdvdKPDQCPKGTRVCGITRVildgddrit 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091     538 -----GSKNLGKFVS--SPTKEKGHIQLSYTDGDdcGSDKKISTNITLVCKPGDLESAPVLRAARSDgcFYEFEWHTAAA 610
Cdd:pfam09451   96 qvipiGGSNLDPEVTrlKTSDEKEGLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVSYDGSQEDD--KLRLEWKTKYA 171

                   .
gi 1709091     611 C 611
Cdd:pfam09451  172 C 172
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
1717-1791 3.50e-03

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 41.69  E-value: 3.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1717 IGRVTGPPIFNPVaNEVYLNF----ESSTHCladRYMNYTSLITFHCKRGVSMGTPKLI-----RTNDCDFVFEWETPIV 1787
Cdd:pfam02157   80 IGRINETQVFNGS-DWIMLIYkggdEYGSHC---GKEKRKAIIMISCNRKVLADNFTIVieereKEQDCFYLFELDSSLA 155

                   ....
gi 1709091    1788 CPDE 1791
Cdd:pfam02157  156 CPPE 159
ATG27 pfam09451
Autophagy-related protein 27;
1361-1518 7.02e-03

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 40.78  E-value: 7.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1361 ECSVqDAAGNSIDLSSLSR-YSDNWEAVTRTGAT-EHYLINVCKSLSPHAGTEP---CPPEAAVCLL---------NGSK 1426
Cdd:pfam09451   18 DCSV-DKGLKKYDLSKLKGpHSVSTTRDTPPSTTnTTWTINICEPLKKDKDVDKpdqCPKGTRVCGItrvildgddRITQ 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709091    1427 PVNLGKVRDGPQWT--------DGVTvLQYVDGdlcPDKIRRRSTIIRFTCSDNQVNSRPLFISAVQDcEYTFSWPTPSA 1498
Cdd:pfam09451   97 VIPIGGSNLDPEVTrlktsdekEGLR-LTLKGG---KWGGNKQDAIIEFICDSDSLTFVSYDGSQEDD-KLRLEWKTKYA 171
                          170       180
                   ....*....|....*....|
gi 1709091    1499 CPVKSNTHDDCQVTNPSTGH 1518
Cdd:pfam09451  172 CEKDESDPDDGDGGGNGGSG 191
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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