integrin alpha-7 isoform X7 [Mus musculus]
Protein Classification
integrin alpha( domain architecture ID 12192630)
integrin alpha is a transmembrane receptor that facilitates cell-extracellular matrix (ECM) adhesion
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||||
| Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
516-1005 | 2.35e-156 | ||||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. : Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 474.12 E-value: 2.35e-156
|
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| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
421-473 | 3.27e-15 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 70.87 E-value: 3.27e-15
|
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| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
362-415 | 1.03e-10 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 58.16 E-value: 1.03e-10
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
48-109 | 3.37e-07 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 48.14 E-value: 3.37e-07
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
483-523 | 1.79e-05 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.13 E-value: 1.79e-05
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
304-355 | 2.38e-04 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 40.05 E-value: 2.38e-04
|
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| Name | Accession | Description | Interval | E-value | ||||||||
| Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
516-1005 | 2.35e-156 | ||||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 474.12 E-value: 2.35e-156
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
421-473 | 3.27e-15 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 70.87 E-value: 3.27e-15
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
362-415 | 1.03e-10 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 58.16 E-value: 1.03e-10
|
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| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
364-402 | 2.48e-10 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 56.36 E-value: 2.48e-10
|
||||||||||||
| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
425-458 | 1.51e-07 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 48.66 E-value: 1.51e-07
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
48-109 | 3.37e-07 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 48.14 E-value: 3.37e-07
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
483-523 | 1.79e-05 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.13 E-value: 1.79e-05
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
304-355 | 2.38e-04 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 40.05 E-value: 2.38e-04
|
||||||||||||
| Name | Accession | Description | Interval | E-value | ||||||||
| Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
516-1005 | 2.35e-156 | ||||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 474.12 E-value: 2.35e-156
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
421-473 | 3.27e-15 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 70.87 E-value: 3.27e-15
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
362-415 | 1.03e-10 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 58.16 E-value: 1.03e-10
|
||||||||||||
| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
364-402 | 2.48e-10 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 56.36 E-value: 2.48e-10
|
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| FG-GAP_3 | pfam13517 | FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ... |
372-445 | 3.32e-09 | ||||||||
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses. Pssm-ID: 433275 [Multi-domain] Cd Length: 61 Bit Score: 54.15 E-value: 3.32e-09
|
||||||||||||
| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
425-458 | 1.51e-07 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 48.66 E-value: 1.51e-07
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
48-109 | 3.37e-07 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 48.14 E-value: 3.37e-07
|
||||||||||||
| FG-GAP_3 | pfam13517 | FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ... |
434-503 | 1.02e-05 | ||||||||
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses. Pssm-ID: 433275 [Multi-domain] Cd Length: 61 Bit Score: 44.14 E-value: 1.02e-05
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
483-523 | 1.79e-05 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.13 E-value: 1.79e-05
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
304-355 | 2.38e-04 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 40.05 E-value: 2.38e-04
|
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| Blast search parameters | ||||
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