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Conserved domains on  [gi|1770184383|gb|QFU14616|]
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envelope glycoprotein D [Psittacid alphaherpesvirus 5]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Herpes_glycop_D super family cl44485
Herpesvirus glycoprotein D/GG/GX domain; This domain is found in several Herpes viruses ...
 29-152 3.01e-07

Herpesvirus glycoprotein D/GG/GX domain; This domain is found in several Herpes viruses glycoproteins. This is a family includes glycoprotein-D (gD or gIV) which is common to herpes simplex virus types 1 and 2, as well as equine herpes, bovine herpes and Marek's disease virus. Glycoprotein-D has been found on the viral envelope and the plasma membrane of infected cells. and gD immunization can produce an immune response to bovine herpes virus (BHV-1). This response is stronger than that of the other major glycoproteins gB (gI) and gC (gIII) in BHV-1. Glycoprotein G (gG)is one of the seven external glycoproteins of HSV1 and HSV2. This family also contains the glycoprotein GX, (gX), initially identified in Pseudorabies virus.


The actual alignment was detected with superfamily member pfam01537:

Pssm-ID: 426313 [Multi-domain]  Cd Length: 118  Bit Score: 48.09  E-value: 3.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770184383  29 TISIDRCDsMVIMDPLLSLTPIMLRVNLAAkkdirvDIYWFYEYGnGCYYPLYHARFRRCRGAIYL--KSCRTVALPMWD 106
Cdd:pfam01537   4 VTYSRGCG-LVLLIPPVNVDSGLPEAAYNA------TVAWFRVGG-GCRRPIYLREYYNCTGNAPPspETCDGYSPTYWR 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1770184383 107 SKFYQN-ATVGprpISLMLyAPNHSMSGKYILLVSVGNHIVGGRVTL 152
Cdd:pfam01537  76 GGGYVSyALVN---ASLLA-APGRFDSGQYRYVIGIGGDLHVGDFTV 118
 
Name Accession Description Interval E-value
Herpes_glycop_D pfam01537
Herpesvirus glycoprotein D/GG/GX domain; This domain is found in several Herpes viruses ...
 29-152 3.01e-07

Herpesvirus glycoprotein D/GG/GX domain; This domain is found in several Herpes viruses glycoproteins. This is a family includes glycoprotein-D (gD or gIV) which is common to herpes simplex virus types 1 and 2, as well as equine herpes, bovine herpes and Marek's disease virus. Glycoprotein-D has been found on the viral envelope and the plasma membrane of infected cells. and gD immunization can produce an immune response to bovine herpes virus (BHV-1). This response is stronger than that of the other major glycoproteins gB (gI) and gC (gIII) in BHV-1. Glycoprotein G (gG)is one of the seven external glycoproteins of HSV1 and HSV2. This family also contains the glycoprotein GX, (gX), initially identified in Pseudorabies virus.


Pssm-ID: 426313 [Multi-domain]  Cd Length: 118  Bit Score: 48.09  E-value: 3.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770184383  29 TISIDRCDsMVIMDPLLSLTPIMLRVNLAAkkdirvDIYWFYEYGnGCYYPLYHARFRRCRGAIYL--KSCRTVALPMWD 106
Cdd:pfam01537   4 VTYSRGCG-LVLLIPPVNVDSGLPEAAYNA------TVAWFRVGG-GCRRPIYLREYYNCTGNAPPspETCDGYSPTYWR 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1770184383 107 SKFYQN-ATVGprpISLMLyAPNHSMSGKYILLVSVGNHIVGGRVTL 152
Cdd:pfam01537  76 GGGYVSyALVN---ASLLA-APGRFDSGQYRYVIGIGGDLHVGDFTV 118
PHA03264 PHA03264
envelope glycoprotein D; Provisional
 29-141 2.28e-04

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 42.30  E-value: 2.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770184383  29 TISIDRCDSM-VIMDPLLSLTpimlrVNLAAKKD---IRVDIYWfYEYGNGCYYPLYHARFRRCRGAIYLKSCRTVALPM 104
Cdd:PHA03264   69 ATSAAACDMLaLIADPQVGRT-----LWEAVRRRrrtYNATVIW-YKIESGCARPLYYMEYAECDPRKHFGYCRYRTPPF 142

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1770184383 105 WDSKFYQNATVGPRPISLMLYAPNHSMSGKYILLVSV 141
Cdd:PHA03264  143 WDTFLAGFAYPTDDELGLLMAAPARLNEGQYRRALYI 179
 
Name Accession Description Interval E-value
Herpes_glycop_D pfam01537
Herpesvirus glycoprotein D/GG/GX domain; This domain is found in several Herpes viruses ...
 29-152 3.01e-07

Herpesvirus glycoprotein D/GG/GX domain; This domain is found in several Herpes viruses glycoproteins. This is a family includes glycoprotein-D (gD or gIV) which is common to herpes simplex virus types 1 and 2, as well as equine herpes, bovine herpes and Marek's disease virus. Glycoprotein-D has been found on the viral envelope and the plasma membrane of infected cells. and gD immunization can produce an immune response to bovine herpes virus (BHV-1). This response is stronger than that of the other major glycoproteins gB (gI) and gC (gIII) in BHV-1. Glycoprotein G (gG)is one of the seven external glycoproteins of HSV1 and HSV2. This family also contains the glycoprotein GX, (gX), initially identified in Pseudorabies virus.


Pssm-ID: 426313 [Multi-domain]  Cd Length: 118  Bit Score: 48.09  E-value: 3.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770184383  29 TISIDRCDsMVIMDPLLSLTPIMLRVNLAAkkdirvDIYWFYEYGnGCYYPLYHARFRRCRGAIYL--KSCRTVALPMWD 106
Cdd:pfam01537   4 VTYSRGCG-LVLLIPPVNVDSGLPEAAYNA------TVAWFRVGG-GCRRPIYLREYYNCTGNAPPspETCDGYSPTYWR 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1770184383 107 SKFYQN-ATVGprpISLMLyAPNHSMSGKYILLVSVGNHIVGGRVTL 152
Cdd:pfam01537  76 GGGYVSyALVN---ASLLA-APGRFDSGQYRYVIGIGGDLHVGDFTV 118
PHA03264 PHA03264
envelope glycoprotein D; Provisional
 29-141 2.28e-04

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 42.30  E-value: 2.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770184383  29 TISIDRCDSM-VIMDPLLSLTpimlrVNLAAKKD---IRVDIYWfYEYGNGCYYPLYHARFRRCRGAIYLKSCRTVALPM 104
Cdd:PHA03264   69 ATSAAACDMLaLIADPQVGRT-----LWEAVRRRrrtYNATVIW-YKIESGCARPLYYMEYAECDPRKHFGYCRYRTPPF 142

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1770184383 105 WDSKFYQNATVGPRPISLMLYAPNHSMSGKYILLVSV 141
Cdd:PHA03264  143 WDTFLAGFAYPTDDELGLLMAAPARLNEGQYRRALYI 179
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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