NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1848603404|gb|QKH64766|]
View 

peptidylprolyl isomerase PrsA [Bacillus cereus]

Protein Classification

peptidylprolyl isomerase PrsA( domain architecture ID 11479869)

peptidylprolyl isomerase PrsA plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins, and it functions as a peptidyl-prolyl cis-trans isomerase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0006457
PubMed:  10228556

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-285 0e+00

peptidylprolyl isomerase PrsA;


:

Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 502.16  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   1 MRGKHIFIITALISILMLAACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMIAQDVITKKYKVSDDDVDKEV 80
Cdd:PRK03002    1 MRGKHIFIITALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLSMNKAIKQSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160
Cdd:PRK03002   81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTDKKELKPYDEVKDSIRK 240
Cdd:PRK03002  161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDLKPYDEVKDSIRK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1848603404 241 NLEEERITDPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
Cdd:PRK03002  241 NLEEERTADPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
 
Name Accession Description Interval E-value
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-285 0e+00

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 502.16  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   1 MRGKHIFIITALISILMLAACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMIAQDVITKKYKVSDDDVDKEV 80
Cdd:PRK03002    1 MRGKHIFIITALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLSMNKAIKQSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160
Cdd:PRK03002   81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTDKKELKPYDEVKDSIRK 240
Cdd:PRK03002  161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDLKPYDEVKDSIRK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1848603404 241 NLEEERITDPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
Cdd:PRK03002  241 NLEEERTADPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 134-266 3.59e-45

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 149.34  E-value: 3.59e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 134 KPEIKASHILVS---------DENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKI 204
Cdd:COG0760     6 PEEVRASHILVKvppsedrakAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1848603404 205 GQISNPVKSPNGYHIIKLTDKKE--LKPYDEVKDSIRKNLEEERItdpifgKKLLQSELKKANI 266
Cdd:COG0760    86 GEISGPVKTQFGYHIIKVEDRRPaeTPPFEEVKQQIRQELFQQAL------EAWLEELRKKAKI 143
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-224 8.79e-28

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 102.76  E-value: 8.79e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1848603404 147 ENEAKEIKKKLDAGA-SFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTD 224
Cdd:pfam00639  18 KAKAEEILEQLKSGEdSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKPGEISGPVETRFGFHIIKLTD 96
 
Name Accession Description Interval E-value
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-285 0e+00

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 502.16  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   1 MRGKHIFIITALISILMLAACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMIAQDVITKKYKVSDDDVDKEV 80
Cdd:PRK03002    1 MRGKHIFIITALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLSMNKAIKQSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160
Cdd:PRK03002   81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTDKKELKPYDEVKDSIRK 240
Cdd:PRK03002  161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDLKPYDEVKDSIRK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1848603404 241 NLEEERITDPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
Cdd:PRK03002  241 NLEEERTADPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 1-277 2.48e-88

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 264.53  E-value: 2.48e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   1 MRGKHIFIITALISI-LMLAACGqknSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMIAQDVITKKYKVSDDDVDKE 79
Cdd:PRK02998    1 MKKKKLFLGTIISCVvLALSACG---SSDNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYKVSDEEAKKQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  80 VQKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLSMNKAIKQSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDA 159
Cdd:PRK02998   78 VEEAKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNN 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 160 GASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTDKKELKPYDEVKDSIR 239
Cdd:PRK02998  158 GEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIR 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1848603404 240 KNLEEERITDPI--FGKKLLQSELKKANIKINDSELEDTF 277
Cdd:PRK02998  238 KDLEQQRLQDTTgkWKQQVVNDLLKDADIKVNDKEFKDTF 277
prsA PRK03095
peptidylprolyl isomerase PrsA;
4-277 3.31e-74

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 228.72  E-value: 3.31e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   4 KHIFIITALISILMLAACGQkNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMIAQDVITKKYKVSDDDVDKEVQKA 83
Cdd:PRK03095    2 KKAMLALAATSVIALSACGT-SSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKYDEM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  84 KSQYGDQFKNVLKNNGLKDEAdFKNQIKFKLSMNKAIKQSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAGASF 163
Cdd:PRK03095   81 KKQYGDQFDTLLKQQGIKEET-LKTGVRAQLAQEKAIEKTITDKELKDNYKPEIKASHILVKDEATAKKVKEELGQGKSF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 164 EELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTDKKEL-KPYDEVKDSIRKNL 242
Cdd:PRK03095  160 EELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVTDIKEPeKSFEQSKADIKKEL 239

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1848603404 243 EEERITDPIFGKKLLQSELKKANIKINDSELEDTF 277
Cdd:PRK03095  240 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLF 274
prsA PRK04405
peptidylprolyl isomerase; Provisional
 4-275 1.68e-46

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 158.02  E-value: 1.68e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   4 KHIFIITALISILM-LAACGqkNSSATVATATDSTITKSDFEKQLKD-RYGKDMLYEMIAQDVITKKY--KVSDDDVDKE 79
Cdd:PRK04405    6 KKWALAAASAGLALsLAGCS--SNQATVATYSGGKITQSQYYKEMKQsSAGKTVLANMIIYRALEKQYgkKVSTKKVDKQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  80 VQKAKSQYGDQFKNVLKNNGLKdEADFKNQIKFKLSMNKAIK--QSVTEKDVKDH---YKPEIKASHILVSDENEAKEIK 154
Cdd:PRK04405   84 YNSYKKQYGSSFDSVLSQNGMT-TSSFKQNLRTNLLSEAALKklKKVTNSQLKKAwksYQPKVTVQHILVSKKSTAETVI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 155 KKLDAGASFEELAKQESQDLLSKEKGGDLGYFNS--GRMAPEFETAAYKLKIGQI-SNPVKSPNGYHIIKLTDKKELKPY 231
Cdd:PRK04405  163 KKLKDGKDFAKLAKKYSTDTATKNKGGKLSAFDStdTTLDSTFKTAAFKLKNGEYtTTPVKTTYGYEVIKMIKHPAKGTF 242

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1848603404 232 DEVKDSIRKNLEEERITDPIFGKKLLQSELKKANIKINDSELED 275
Cdd:PRK04405  243 SDHKKALTKQIYAKWASDSSVMQRVISKVLKKANVSIKDKDLKD 286
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 134-266 3.59e-45

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 149.34  E-value: 3.59e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 134 KPEIKASHILVS---------DENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKI 204
Cdd:COG0760     6 PEEVRASHILVKvppsedrakAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1848603404 205 GQISNPVKSPNGYHIIKLTDKKE--LKPYDEVKDSIRKNLEEERItdpifgKKLLQSELKKANI 266
Cdd:COG0760    86 GEISGPVKTQFGYHIIKVEDRRPaeTPPFEEVKQQIRQELFQQAL------EAWLEELRKKAKI 143
prsA PRK00059
peptidylprolyl isomerase; Provisional
 7-273 1.86e-40

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 142.93  E-value: 1.86e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   7 FIITALISILMLAACG----QKNSSA----TVATATDSTITKSDFEK---------QLKDRYGKD--------------- 54
Cdd:PRK00059    7 LVASLLVGVFIFSAVGcnmiEKTPEAiaksTVATVNGEKITRGDLDKdpkmqqvleQLKQQYGDNyekneqvkeqikqqk 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  55 --MLYEMIAQDVITKKYK-----VSDDDVDKEVQKAKSQY-------GDQFKNVLKNNGLKdEADFKNQIKFKLSMNKAI 120
Cdd:PRK00059   87 eqILDSLITEKVLLQKAKelkliPSEEELNKEVDKKINEIkkqfnndEEQFEEALKATGFT-EETFKEYLKNQIIIEKVI 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 121 KQ-----SVTEKDVKDHY----------KPEIKASHILVSDENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGY 185
Cdd:PRK00059  166 NEvvkdvKVTDKDAQKYYnenkskftekPNTMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDLGD 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 186 --FNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTDKKE--LKPYDEVKDSIRKNLEEERITDpIFGKKLLQSEl 261
Cdd:PRK00059  246 vpYSDSGYDKEFMDGAKALKEGEISAPVKTQFGYHIIKAIKKKEypVKPFDSVKEDIKKQLLQEKQSE-VFKKKIEEWK- 323

                         330
                  ....*....|..
gi 1848603404 262 KKANIKINDSEL 273
Cdd:PRK00059  324 KALKVKKYEKNL 335
prsA PRK01326
foldase protein PrsA; Reviewed
 1-278 3.95e-33

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 123.00  E-value: 3.95e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   1 MRGKHIFIITALISILMLAACGQKNSSATVATATDSTITKSDFEKQLK-DRYGKDMLYEMIAQDVITKKY--KVSDDDVD 77
Cdd:PRK01326    1 MKKKLIAGAVTLLSVATLAACSKTNENTKVISMKGDTITVSDFYNQVKnNPSAQQAMLNLTISRVFEKQYgdKVSDKEVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  78 KEVQKAKSQYGDQFKNVLKNNGLKDEAdFKNQIK----FKLSMNKAIKQSVTEKDVK---DHYKPEIKASHILVSDENEA 150
Cdd:PRK01326   81 KAYAKTAKQYGASFSRALAQAGLTPET-YKAQIRtsklVEYAVKEAAKKELTDEAYKkayEEYTPEVTAQIIRLDNEDKA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 151 KEIKKKLDA-GASFEELAKQESQdllSKEKGGDLGYFNSGRMAPE-FETAAYKLKIGQISNPVKSP------NGYHIIKL 222
Cdd:PRK01326  160 KSVLEEAKAeGADFAQIAKENTT---TKEKKGEYKFDSGSTNVPEqVKKAAFALDEDGVSDVISVLdptayqSKYYIVKV 236

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1848603404 223 TDKKELKP-YDEVKDSIRKNLEEERITDPIFGKKLLQSELKKANIKINDSELEDTFT 278
Cdd:PRK01326  237 TKKTEKKSdWKDYKKRLKAIILAQKQNDSNFQNKVIAKALDKANVKIKDKAFANILA 293
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-224 8.79e-28

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 102.76  E-value: 8.79e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1848603404 147 ENEAKEIKKKLDAGA-SFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYHIIKLTD 224
Cdd:pfam00639  18 KAKAEEILEQLKSGEdSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKPGEISGPVETRFGFHIIKLTD 96
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 136-226 4.93e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 101.67  E-value: 4.93e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 136 EIKASHILVS-------DENEAK----EIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKI 204
Cdd:pfam13616  15 SVKASHILISysqavsrTEEEAKakadSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMVKEFEDAVFSLKV 94

                          90       100
                  ....*....|....*....|..
gi 1848603404 205 GQISNPVKSPNGYHIIKLTDKK 226
Cdd:pfam13616  95 GEISGVVKTQFGFHIIKVTDKK 116
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 9-270 1.97e-23

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 97.08  E-value: 1.97e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   9 ITALISILMLAACGQKNSSATVATATDSTITKSDFEKQLKD-RYGKDMLYEMIAQDVITKKY--KVSDDDVDKEVQKAKS 85
Cdd:PRK12450   11 VVTLATVVTLSACQSSHNNTKLVSMKGDTITVSDFYNETKNtELAQKAMLSLVISRVFETQYanKVSDKEVEKAYKQTAD 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  86 QYGDQFKNVLKNNGLKDEAdFKNQIKFKLSMNKAIK-----QSVTEKDVK---DHYKPEIKASHILVSDENEAKEIKKKL 157
Cdd:PRK12450   91 QYGTSFKTVLAQSGLTPET-YKKQIRLTKLVEYAVKeqaknETISKKDYRqayDAYTPTMTAEIMQFEKEEDAKAALEAV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 158 DA-GASFEELAKQESQdllSKEKGGDLGyFNSG--RMAPEFETAAYKLKIGQIS------NPVKSPNGYHIIKLTDKKEL 228
Cdd:PRK12450  170 KAeGADFAAIAKEKTI---AADKKTTYT-FDSGetTLPAEVVRAASGLKEGNRSeiitalDPATSKRTYHIIKVTKKATK 245

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1848603404 229 KP-YDEVKDSIRKNLEEERITDPIFGKKLLQSELKKANIKIND 270
Cdd:PRK12450  246 KAdWKAYQKRLKDIIVTGKLKDPDFQNKVIAKALDKANVKIKD 288
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 59-271 1.39e-22

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 97.00  E-value: 1.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  59 MIAQDVITKKYKVSDDDVdkevqkakSQYGDQFKNvlknnglkdeaDFKNQIKFKLS---MNKAI---KQSVTEKDVKDH 132
Cdd:PRK10788  197 TIDVNALAAKQTVTDEEI--------KSYYDQNKN-----------NFMAPEQFKVSyikLDAATmqqKITVSDADIQAY 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 133 YK--------PE-IKASHILVSDENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLK 203
Cdd:PRK10788  258 YDqhqdqftqPErKRYSIIQTKTEAEAKAVLDELKKGADFATLAKEKSTDIISARNGGDLGWLEPATTPDELKNAGLKEK 337

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 204 iGQISNPVKSPNGYHIIKLTDKK--ELKPYDEVKDSIRKNLEEERITDPIFGkklLQSELKKANIKINDS 271
Cdd:PRK10788  338 -GQLSGVIKSSVGFLIVRLDDIQpaKVKPLSEVRDDIAAKVKQEKALDAYYA---LQQKVSDAASNDNES 403
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 137-221 1.16e-17

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 76.60  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 137 IKASHILV-------------------SDENEAKEIKKKL----DAGASFEELAKQESqDLLSKEKGGDLGYFNSGRMAP 193
Cdd:PTZ00356    6 VRAAHLLIkhtgsrnpvsrrtgkpvtrSKEEAIKELAKWReqivSGEKTFEEIARQRS-DCGSAAKGGDLGFFGRGQMQK 84

                          90       100
                  ....*....|....*....|....*...
gi 1848603404 194 EFETAAYKLKIGQISNPVKSPNGYHIIK 221
Cdd:PTZ00356   85 PFEDAAFALKVGEISDIVHTDSGVHIIL 112
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
124-236 3.35e-15

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 70.16  E-value: 3.35e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 124 VTEKDVKDHY--------KPEIKASHILVSDENEAKEIKKKLDAGASFEELAKQESQDLlskEKGGDLGYF-NSGRMAPE 194
Cdd:pfam13145   1 VTEEELKAYYeenkdefsTPEGRLLEILVFKDQVAADAALALLKAGALEDFAALAKGEG---IKAATLDIVeSAELLPEE 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1848603404 195 FETAAYKLKIGQISNPVKSPNGYHIIKLTDKKE--LKPYDEVKD 236
Cdd:pfam13145  78 LAKAAFALKPGEVSGPIKTGNGYYVVRVTEIKPaqPLPFEEAKD 121
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 139-226 8.93e-14

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 65.82  E-value: 8.93e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 139 ASHILVSDENEAKEIKKKLDAGASFEELAKQESQdLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIGQISNPVKSPNGYH 218
Cdd:PRK15441    7 ALHILVKEEKLALDLLEQIKNGADFGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYH 85


                  ....*...
gi 1848603404 219 IIKLTDKK 226
Cdd:PRK15441   86 IIKVLYRN 93
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 136-235 1.20e-11

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 64.38  E-value: 1.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 136 EIKASHILVS-------DENEAK--EIKKKLDAG-ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKIG 205
Cdd:PRK10770  266 EVHARHILLKpspimtdEQARAKleQIAADIKSGkTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALMRLNKG 345

                          90       100       110
                  ....*....|....*....|....*....|
gi 1848603404 206 QISNPVKSPNGYHIIKLTDKKELKPYDEVK 235
Cdd:PRK10770  346 QISAPVHSSFGWHLIELLDTRQVDKTDAAQ 375
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 70-224 4.23e-06

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 47.43  E-value: 4.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404  70 KVSDDDVDKEVQKAKSQYG---DQFKNVLKNNGLkDEADFKNQIKFKLSM----NKAIKQSVT----EKDV-------KD 131
Cdd:PRK10770   72 KISDEQLDQAIANIAAQNNmtlDQMRSRLAYDGL-NYNTYRNQIRKEMIIsevrNNEVRRRITilpqEVDSlakqignQN 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404 132 HYKPEIKASHILV------------SDENEAKEIKKKLDAGASFEELAKQESQDLLSKeKGGDLGYFNSGRMAPEFETAA 199
Cdd:PRK10770  151 DASTELNLSHILIplpenptqdqvdEAESQARSIVDQARNGADFGKLAIAYSADQQAL-KGGQMGWGRIQELPGLFAQAL 229

                         170       180
                  ....*....|....*....|....*
gi 1848603404 200 YKLKIGQISNPVKSPNGYHIIKLTD 224
Cdd:PRK10770  230 STAKKGDIVGPIRSGVGFHILKVND 254
SurA_N_3 pfam13624
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 6-118 8.71e-05

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 433358 [Multi-domain]  Cd Length: 162  Bit Score: 42.17  E-value: 8.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1848603404   6 IFIITALIsILMLAACG----QKNSSATVATATDSTITKSDFEK-------QLKDRYGKDM--------------LYEMI 60
Cdd:pfam13624  14 AKIILGLI-ILSFVFWGvgsyFSGGGGAVAKVNGEKISRAEFQRayrrqldQLRQQFGPNLdaelldelglrqqvLDQLI 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1848603404  61 AQDVI---TKKYK--VSDDDVDKEVQKAKS-QYGDQF-----KNVLKNNGLKdEADFKNQIKFKLSMNK 118
Cdd:pfam13624  93 DRALLlqeAKKLGlaVSDEEVRQAIASIPAfQEDGKFdkeryRQLLRANGLT-PAEFEASLRQDLLLQQ 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH