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Conserved domains on  [gi|18640225|ref|NP_570299|]
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EEV Host range protein [Swinepox virus]

Protein Classification

PHA02817 family protein( domain architecture ID 11476095)

PHA02817 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02817 PHA02817
EEV Host range protein; Provisional
 2-226 2.16e-103

EEV Host range protein; Provisional


:

Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 298.39  E-value: 2.16e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225    2 LLSLFILMYYMPNVIYCSCD-----IPPDIVNGEIYDKKEVYSKGDSISYICGENKIGIPYSLIGNDVITCNKDGKWYPD 76
Cdd:PHA02817   1 MKNIHMLLILLCNKVYSLCDlnkccYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRGVRYTLVGEKNIICEKDGKWNKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225   77 PPRCEMIICRFPALQNGYVNGIPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPICIKNDKSLSIIIYNKN 156
Cdd:PHA02817  81 FPVCKIIRCRFPALQNGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNITYNKIYINKV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18640225  157 --DDDFKDldneDIVNANMRSINNTLEInitnNNISETTLLIILgSIGSIFIFGIILLIYSCSNSVNN--KYSK 226
Cdd:PHA02817 161 niDDNFFN----QINNSNTYYFDKILQI----NNVNRYTLIFFV-VVSIKILFGFVFIFFSCNKKPLDsiKYYK 225
 
Name Accession Description Interval E-value
PHA02817 PHA02817
EEV Host range protein; Provisional
 2-226 2.16e-103

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 298.39  E-value: 2.16e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225    2 LLSLFILMYYMPNVIYCSCD-----IPPDIVNGEIYDKKEVYSKGDSISYICGENKIGIPYSLIGNDVITCNKDGKWYPD 76
Cdd:PHA02817   1 MKNIHMLLILLCNKVYSLCDlnkccYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRGVRYTLVGEKNIICEKDGKWNKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225   77 PPRCEMIICRFPALQNGYVNGIPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPICIKNDKSLSIIIYNKN 156
Cdd:PHA02817  81 FPVCKIIRCRFPALQNGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNITYNKIYINKV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18640225  157 --DDDFKDldneDIVNANMRSINNTLEInitnNNISETTLLIILgSIGSIFIFGIILLIYSCSNSVNN--KYSK 226
Cdd:PHA02817 161 niDDNFFN----QINNSNTYYFDKILQI----NNVNRYTLIFFV-VVSIKILFGFVFIFFSCNKKPLDsiKYYK 225
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 20-81 4.87e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 61.71  E-value: 4.87e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18640225  20 CDIPPDIVNGEIYDKKEVYSKGDSISYICGENkigipYSLIGNDVITCNKDGKWYPDPPRCE 81
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEG-----YTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
20-80 6.95e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 61.36  E-value: 6.95e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18640225    20 CDIPPDIVNGEIYDKKEVYSKGDSISYICGENkigipYSLIGNDVITCNKDGKWYPDPPRC 80
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPG-----YRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 20-80 9.57e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.31  E-value: 9.57e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18640225     20 CDIPPDIVNGEIYDKKEVYSKGDSISYICGENkigipYSLIGNDVITCNKDGKWYPDPPRC 80
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPG-----YTLIGSSTITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02817 PHA02817
EEV Host range protein; Provisional
 2-226 2.16e-103

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 298.39  E-value: 2.16e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225    2 LLSLFILMYYMPNVIYCSCD-----IPPDIVNGEIYDKKEVYSKGDSISYICGENKIGIPYSLIGNDVITCNKDGKWYPD 76
Cdd:PHA02817   1 MKNIHMLLILLCNKVYSLCDlnkccYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRGVRYTLVGEKNIICEKDGKWNKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225   77 PPRCEMIICRFPALQNGYVNGIPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPICIKNDKSLSIIIYNKN 156
Cdd:PHA02817  81 FPVCKIIRCRFPALQNGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNITYNKIYINKV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18640225  157 --DDDFKDldneDIVNANMRSINNTLEInitnNNISETTLLIILgSIGSIFIFGIILLIYSCSNSVNN--KYSK 226
Cdd:PHA02817 161 niDDNFFN----QINNSNTYYFDKILQI----NNVNRYTLIFFV-VVSIKILFGFVFIFFSCNKKPLDsiKYYK 225
PHA02639 PHA02639
EEV host range protein; Provisional
 13-198 1.21e-60

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 192.19  E-value: 1.21e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225   13 PNVIYCSCDIPPDIVNGEIYDKKEVYSKGDSISYICGENKiGIPYSLIGNDVITCNKDGKWYPDPPRCEMIICRFPALQN 92
Cdd:PHA02639  78 PFCMLKECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHK-GVQYSLVGNEKITCIQDKSWKPDPPICKMINCRFPALQN 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225   93 GYVNGIPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPICIKNDKSLSIIIYNKNDDDFKDLDNEDIVNAN 172
Cdd:PHA02639 157 GYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCVRNKPIDDIIYLKPVDDNFDDLDNEDKINTI 236

                        170       180
                 ....*....|....*....|....*..
gi 18640225  173 MRSIN-NTLEINITNNNISETTLLIIL 198
Cdd:PHA02639 237 LHNNDaNSTRINQEKENGNIFTVIILL 263
PHA02831 PHA02831
EEV host range protein; Provisional
 19-175 7.97e-33

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 119.71  E-value: 7.97e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225   19 SCDIPPDIVNGEIYDKKEVYSKGDSISYICGENKIGiPYSLIGNDVITCnKDGKWYPDPPRCEMIICRFPALQNGYVNGI 98
Cdd:PHA02831  77 NCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLE-KYSIVGNETVKC-INKQWVPKYPVCKLIRCKYPALQNGFLNVF 154

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18640225   99 psNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPICIKnDKSLSIIIYNKNDDDFKDLDNEDIVNANMRS 175
Cdd:PHA02831 155 --EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVK-DKVHNEIQPNYLFDDLDEDFNNSTTNYNMQQ 228
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 9-143 3.69e-21

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 88.94  E-value: 3.69e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225    9 MYYMPNVIYCS---CDIPPDIVNGEIYDKKEVYSKGDSISYICGENkigipYSLIGNDVITCNkDGKWyPDPPRCEMIIC 85
Cdd:PHA02927 134 MVWNPEAPICEsvkCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSG-----YSLIGNSGVLCS-GGEW-SDPPTCQIVKC 206

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 18640225   86 RFPALQNGYVNGiPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPICIK 143
Cdd:PHA02927 207 PHPTISNGYLSS-GFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCVR 263
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 20-81 4.87e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 61.71  E-value: 4.87e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18640225  20 CDIPPDIVNGEIYDKKEVYSKGDSISYICGENkigipYSLIGNDVITCNKDGKWYPDPPRCE 81
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEG-----YTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
20-80 6.95e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 61.36  E-value: 6.95e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18640225    20 CDIPPDIVNGEIYDKKEVYSKGDSISYICGENkigipYSLIGNDVITCNKDGKWYPDPPRC 80
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPG-----YRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 20-80 9.57e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.31  E-value: 9.57e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18640225     20 CDIPPDIVNGEIYDKKEVYSKGDSISYICGENkigipYSLIGNDVITCNKDGKWYPDPPRC 80
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPG-----YTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 85-142 2.89e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.69  E-value: 2.89e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 18640225  85 CRFP-ALQNGYVngIPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPICI 142
Cdd:cd00033   1 CPPPpVPENGTV--TGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 85-141 3.63e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 3.63e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 18640225     85 CRFP-ALQNGYVNgiPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPIC 141
Cdd:smart00032   1 CPPPpDIENGTVT--SSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 23-196 1.97e-08

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 53.55  E-value: 1.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225   23 PPDIVNGEIYDKKEVYSKGDSISYICGenkigIPYSLIGNDVITCNKDGkwYPDPPRCEMIiCRFPALQNGYVNGipsnK 102
Cdd:PHA02954 132 PLQLEHGSCQPVKEKYSFGEHITINCD-----VGYEVIGASYISCTANS--WNVIPSCQQK-CDIPSLSNGLISG----S 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18640225  103 KFYYKQKVSFTCKDGFLLAGEPYSICnINSTWFPDIPICIKNDKSLSIIiyNKNDDDFKDLD--NEDIVN--ANMRSINN 178
Cdd:PHA02954 200 TFSIGGVIHLSCKSGFTLTGSPSSTC-IDGKWNPVLPICVRSNEEFDPV--DDGPDDETDLSklSKDVVQyeQEIESLEA 276

                        170
                 ....*....|....*...
gi 18640225  179 TLEINITNNNISETTLLI 196
Cdd:PHA02954 277 TYHIIIVALTIMGVIFLI 294
Sushi pfam00084
Sushi repeat (SCR repeat);
88-141 2.24e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.34  E-value: 2.24e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 18640225    88 PALQNGYVngIPSNKKFYYKQKVSFTCKDGFLLAGEPYSICNINSTWFPDIPIC 141
Cdd:pfam00084   5 PDIPNGKV--SATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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