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Conserved domains on  [gi|187956265|gb|AAI50745|]
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RIKEN cDNA 2700049A03 gene [Mus musculus]

Protein Classification

TALPID3 domain-containing protein( domain architecture ID 12173090)

TALPID3 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 102-1332 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


:

Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1865.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   102 DIFISQYTMGQKDALRTVLKQKAQSMPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIK 181
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   182 VQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDA 261
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   262 ALKASSLQLGMSTS-RAVGKY--SGKLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 336
Cdd:pfam15324  161 ALKAVSLQPSSVTSsRAVEKSgnSSEDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   337 GKITKRESPTEEKENMEMNSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERG 416
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   417 TAQVPVPKYNDVVHDLGQ-KKQASDML-----------------QIKQSPVTLRLSDHP------------------HNP 460
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQlKKEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSP 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   461 ALLQTTN-TRSVLKDAAKILRGVQNNKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEI 539
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   540 QDELMRKDYEQKRFDPKNQRNKKALTM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQ 611
Cdd:pfam15324  481 QDELARKDYEQKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   612 KeRSGLLKSATTLQDEDYMLQIYGKPVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASR 691
Cdd:pfam15324  561 K-KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKP 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   692 MKMDSKIQHPITAlPHADQQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPAS 771
Cdd:pfam15324  640 VKTDSKMQHSVTA-PHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSS 718

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   772 RKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEE 849
Cdd:pfam15324  719 RKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEE 798

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   850 VPLPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQ 929
Cdd:pfam15324  799 VKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVD 878

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   930 WVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVML 1009
Cdd:pfam15324  879 WVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIML 958

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1010 ADREAERQRAAATSVPGDLSGTETNLLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEK 1088
Cdd:pfam15324  959 GDREAQREPPVAASVPGDLPTKETLLP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEK 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1089 GSD-MPAVMLVSTPTRTPVATPPPVAALTPTFSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA 1167
Cdd:pfam15324 1034 GADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVA 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1168 -NEEPESVDFSaqPAPPEPAPSAPLPEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKR 1245
Cdd:pfam15324 1114 rDEEPESVVLP--ASPPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRA 1191

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1246 PGD--LFLMNINDSLSSTLQDALEMEDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELS 1319
Cdd:pfam15324 1192 LEEggLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELS 1271

                         1290
                   ....*....|...
gi 187956265  1320 EGQRLVLKAAEDI 1332
Cdd:pfam15324 1272 EGQRPRLTAAAEN 1284
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 102-1332 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1865.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   102 DIFISQYTMGQKDALRTVLKQKAQSMPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIK 181
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   182 VQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDA 261
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   262 ALKASSLQLGMSTS-RAVGKY--SGKLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 336
Cdd:pfam15324  161 ALKAVSLQPSSVTSsRAVEKSgnSSEDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   337 GKITKRESPTEEKENMEMNSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERG 416
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   417 TAQVPVPKYNDVVHDLGQ-KKQASDML-----------------QIKQSPVTLRLSDHP------------------HNP 460
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQlKKEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSP 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   461 ALLQTTN-TRSVLKDAAKILRGVQNNKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEI 539
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   540 QDELMRKDYEQKRFDPKNQRNKKALTM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQ 611
Cdd:pfam15324  481 QDELARKDYEQKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   612 KeRSGLLKSATTLQDEDYMLQIYGKPVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASR 691
Cdd:pfam15324  561 K-KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKP 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   692 MKMDSKIQHPITAlPHADQQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPAS 771
Cdd:pfam15324  640 VKTDSKMQHSVTA-PHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSS 718

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   772 RKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEE 849
Cdd:pfam15324  719 RKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEE 798

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   850 VPLPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQ 929
Cdd:pfam15324  799 VKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVD 878

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   930 WVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVML 1009
Cdd:pfam15324  879 WVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIML 958

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1010 ADREAERQRAAATSVPGDLSGTETNLLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEK 1088
Cdd:pfam15324  959 GDREAQREPPVAASVPGDLPTKETLLP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEK 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1089 GSD-MPAVMLVSTPTRTPVATPPPVAALTPTFSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA 1167
Cdd:pfam15324 1034 GADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVA 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1168 -NEEPESVDFSaqPAPPEPAPSAPLPEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKR 1245
Cdd:pfam15324 1114 rDEEPESVVLP--ASPPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRA 1191

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1246 PGD--LFLMNINDSLSSTLQDALEMEDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELS 1319
Cdd:pfam15324 1192 LEEggLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELS 1271

                         1290
                   ....*....|...
gi 187956265  1320 EGQRLVLKAAEDI 1332
Cdd:pfam15324 1272 EGQRPRLTAAAEN 1284
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 1041-1446 6.74e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.21  E-value: 6.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1041 APVATPQPTPPCSPSPVREHVRVKTPDSSPCESDPDAASSIKEIRVEKGSDMPAVmlVSTPTRTPvatpppvaaltptfs 1120
Cdd:PTZ00449  548 KPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRS--AQRPTRPK--------------- 610

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1121 etsidklklsSPELPKpwdSGDLPLDEENPNSLQELPHPRAVVMSVANEEPESvdfsaqpappepapsAPLPEGTKAPSL 1200
Cdd:PTZ00449  611 ----------SPKLPE---LLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEG---------------PKIIKSPKPPKS 662

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1201 QRVP-------------SSGSSTLENTLSTVTETETLDRHISEG-----EILFSCGQNLATKRPGDlflmnindsLSSTL 1262
Cdd:PTZ00449  663 PKPPfdpkfkekfyddyLDAAAKSKETKTTVVLDESFESILKETlpetpGTPFTTPRPLPPKLPRD---------EEFPF 733

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1263 QDALEMEDDPPSEGQVIRRPHKKR---HEDAIVALLTKQQRELLvsqQEEDLDNSVGELSEGQRLVlKAAEDISAGPSGq 1339
Cdd:PTZ00449  734 EPIGDPDAEQPDDIEFFTPPEEERtffHETPADTPLPDILAEEF---KEEDIHAETGEPDEAMKRP-DSPSEHEDKPPG- 808

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1340 mlppTSPAEPSYQHADPRLVLQQSDMAS--GNICEDlcASHGPMSLRELELQPDSnlilpithTTTAVSDGNLPEAAEDF 1417
Cdd:PTZ00449  809 ----DHPSLPKKRHRLDGLALSTTDLESdaGRIAKD--ASGKIVKLKRSKSFDDL--------TTVEEAEEMGAEARKIV 874

                         410       420
                  ....*....|....*....|....*....
gi 187956265 1418 SQYQQKQDSDikQVEHKPIQRHLTSVRNK 1446
Cdd:PTZ00449  875 VDDDGTEADD--EDTHPPEEKHKSEVRRR 901
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 102-1332 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1865.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   102 DIFISQYTMGQKDALRTVLKQKAQSMPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIK 181
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   182 VQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDA 261
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   262 ALKASSLQLGMSTS-RAVGKY--SGKLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 336
Cdd:pfam15324  161 ALKAVSLQPSSVTSsRAVEKSgnSSEDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   337 GKITKRESPTEEKENMEMNSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERG 416
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   417 TAQVPVPKYNDVVHDLGQ-KKQASDML-----------------QIKQSPVTLRLSDHP------------------HNP 460
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQlKKEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSP 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   461 ALLQTTN-TRSVLKDAAKILRGVQNNKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEI 539
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   540 QDELMRKDYEQKRFDPKNQRNKKALTM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQ 611
Cdd:pfam15324  481 QDELARKDYEQKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   612 KeRSGLLKSATTLQDEDYMLQIYGKPVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASR 691
Cdd:pfam15324  561 K-KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKP 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   692 MKMDSKIQHPITAlPHADQQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPAS 771
Cdd:pfam15324  640 VKTDSKMQHSVTA-PHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSS 718

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   772 RKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEE 849
Cdd:pfam15324  719 RKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEE 798

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   850 VPLPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQ 929
Cdd:pfam15324  799 VKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVD 878

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265   930 WVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVML 1009
Cdd:pfam15324  879 WVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIML 958

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1010 ADREAERQRAAATSVPGDLSGTETNLLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEK 1088
Cdd:pfam15324  959 GDREAQREPPVAASVPGDLPTKETLLP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEK 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1089 GSD-MPAVMLVSTPTRTPVATPPPVAALTPTFSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA 1167
Cdd:pfam15324 1034 GADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVA 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1168 -NEEPESVDFSaqPAPPEPAPSAPLPEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKR 1245
Cdd:pfam15324 1114 rDEEPESVVLP--ASPPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRA 1191

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265  1246 PGD--LFLMNINDSLSSTLQDALEMEDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELS 1319
Cdd:pfam15324 1192 LEEggLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELS 1271

                         1290
                   ....*....|...
gi 187956265  1320 EGQRLVLKAAEDI 1332
Cdd:pfam15324 1272 EGQRPRLTAAAEN 1284
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 1041-1446 6.74e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.21  E-value: 6.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1041 APVATPQPTPPCSPSPVREHVRVKTPDSSPCESDPDAASSIKEIRVEKGSDMPAVmlVSTPTRTPvatpppvaaltptfs 1120
Cdd:PTZ00449  548 KPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRS--AQRPTRPK--------------- 610

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1121 etsidklklsSPELPKpwdSGDLPLDEENPNSLQELPHPRAVVMSVANEEPESvdfsaqpappepapsAPLPEGTKAPSL 1200
Cdd:PTZ00449  611 ----------SPKLPE---LLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEG---------------PKIIKSPKPPKS 662

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1201 QRVP-------------SSGSSTLENTLSTVTETETLDRHISEG-----EILFSCGQNLATKRPGDlflmnindsLSSTL 1262
Cdd:PTZ00449  663 PKPPfdpkfkekfyddyLDAAAKSKETKTTVVLDESFESILKETlpetpGTPFTTPRPLPPKLPRD---------EEFPF 733

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1263 QDALEMEDDPPSEGQVIRRPHKKR---HEDAIVALLTKQQRELLvsqQEEDLDNSVGELSEGQRLVlKAAEDISAGPSGq 1339
Cdd:PTZ00449  734 EPIGDPDAEQPDDIEFFTPPEEERtffHETPADTPLPDILAEEF---KEEDIHAETGEPDEAMKRP-DSPSEHEDKPPG- 808

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187956265 1340 mlppTSPAEPSYQHADPRLVLQQSDMAS--GNICEDlcASHGPMSLRELELQPDSnlilpithTTTAVSDGNLPEAAEDF 1417
Cdd:PTZ00449  809 ----DHPSLPKKRHRLDGLALSTTDLESdaGRIAKD--ASGKIVKLKRSKSFDDL--------TTVEEAEEMGAEARKIV 874

                         410       420
                  ....*....|....*....|....*....
gi 187956265 1418 SQYQQKQDSDikQVEHKPIQRHLTSVRNK 1446
Cdd:PTZ00449  875 VDDDGTEADD--EDTHPPEEKHKSEVRRR 901
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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