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Conserved domains on  [gi|1886411808|gb|QMV34620|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Galegeeska revoilii]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 2.38e-52

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 164.59  E-value: 2.38e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   1 MMYNV-LLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPE 79
Cdd:MTH00109    2 MMYIVfILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  80 AWGSSKVIVGGVVLGVLAEILVLGWLFlGMNDGVYDVVMNGFDNNLVELGVGSGLVRGDYVGSSLLYGSGSWLLLISGWV 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVL-KDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....
gi 1886411808 160 LFVSIFIIIEIVRG 173
Cdd:MTH00109  161 LFIGVFVIIEITRG 174
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 2.38e-52

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 164.59  E-value: 2.38e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   1 MMYNV-LLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPE 79
Cdd:MTH00109    2 MMYIVfILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  80 AWGSSKVIVGGVVLGVLAEILVLGWLFlGMNDGVYDVVMNGFDNNLVELGVGSGLVRGDYVGSSLLYGSGSWLLLISGWV 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVL-KDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....
gi 1886411808 160 LFVSIFIIIEIVRG 173
Cdd:MTH00109  161 LFIGVFVIIEITRG 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
16-170 8.74e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 45.96  E-value: 8.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  16 VGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPEAWGSSKVIVGGVVLGV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1886411808  96 LAeILVLGWLFLGMNDGVYDVVMNGFDNNLVELGVgsglvrgdyvgssLLYGSGSWLLLISGWVLFVSIFIIIEI 170
Cdd:pfam00499  81 LL-LALLLLVLLSASLTPAAAAAAPDVGNIEAIGE-------------LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-173 2.38e-52

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 164.59  E-value: 2.38e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   1 MMYNV-LLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPE 79
Cdd:MTH00109    2 MMYIVfILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  80 AWGSSKVIVGGVVLGVLAEILVLGWLFlGMNDGVYDVVMNGFDNNLVELGVGSGLVRGDYVGSSLLYGSGSWLLLISGWV 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVL-KDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....
gi 1886411808 160 LFVSIFIIIEIVRG 173
Cdd:MTH00109  161 LFIGVFVIIEITRG 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 5-173 5.78e-31

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 110.23  E-value: 5.78e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   5 VLLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPEAWGSS 84
Cdd:MTH00138    6 SLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSW 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  85 KVIVGGVVLGVLaeILVLGWLFLGMNDGVYDVVMNGFDNNLVelgvgsglVRGDYVGSSLLYGSGSWLLLISGWVLFVSI 164
Cdd:MTH00138   86 SVLGYVVGYLVG--VVLAAGLFWGGWYEGSWVVVDELKEFSV--------LRGDVGGVALMYSSGGGMLVICAWVLLLTL 155


                  ....*....
gi 1886411808 165 FIIIEIVRG 173
Cdd:MTH00138  156 FVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-174 3.24e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 108.01  E-value: 3.24e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   1 MMY-NVLLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPE 79
Cdd:MTH00065    1 MMYlGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  80 AWGSSKVIVGGVVLGVlaeILVLGWLFLGMNDGVYDVVMNGfdnnlvelGVGSGLVRGDYVGSSLLYGSGSWLLLISGWV 159
Cdd:MTH00065   81 AWGSWSVLVYVLFYLL---LLIVGYILFGCNFSLEFLFTNY--------DTEFSVVGYDWGGVGLMYSSGGWFLMISGWV 149

                         170
                  ....*....|....*
gi 1886411808 160 LFVSIFIIIEIVRGV 174
Cdd:MTH00065  150 LLLTLFVVLEVTRGL 164
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 4.77e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 94.82  E-value: 4.77e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   1 MMYNV-LLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPE 79
Cdd:MTH00115    1 MMYFVfLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  80 AWGSSKVIVGGVVLGVlaeILVLGWLFLGMNDGVYDVVMNGFDnnlvelGVGSGLVRGDYVGSSLLYGSGSWLLLISGWV 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVL---VVVVVGVVVGGLWGMEGVGVVTVD------SGGLFVVRLDFSGVSLFYSSGGGGLLVCGWG 151

                         170
                  ....*....|....
gi 1886411808 160 LFVSIFIIIEIVRG 173
Cdd:MTH00115  152 LLLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-174 1.60e-14

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 67.32  E-value: 1.60e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   1 MMYNVLLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPEA 80
Cdd:MTH00214    2 LYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPES 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  81 WGSSKVIvggvvlgvlaeiLVLGWLFLGMNDGVYDVVMNGFDNNLVELGVGSGLvrgDYVGSSLLYGSGSWLLLISGWVL 160
Cdd:MTH00214   82 WGGWSVL------------LFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNL---DLSGVSDLYSRGFFLLLLGGVVL 146

                         170
                  ....*....|....
gi 1886411808 161 FVSIFIIIEIVRGV 174
Cdd:MTH00214  147 FLVLFVVLELVRGL 160
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 2-174 2.63e-08

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 50.67  E-value: 2.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808   2 MYNVLLSVVFVLGMVGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPeaw 81
Cdd:MTH00045    1 MVFYLFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP--- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  82 gsskvivggvVLGVLAEILVLGWLFLGMNDGVYDVVmNGFDNNLVELGVGSGLvrgdyVGSSLLYGSGSWLLLISGWVLF 161
Cdd:MTH00045   78 ----------SVSNLGEVLVLSLLLSLWVFISFDNF-LELSNNNWSLVSLSDL-----VGSSELYNSGGLYLLLGGFILL 141

                         170
                  ....*....|...
gi 1886411808 162 VSIFIIIEIVRGV 174
Cdd:MTH00045  142 VALVVALVISFGH 154
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
16-170 8.74e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 45.96  E-value: 8.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1886411808  16 VGVSSKPSPIFGGLGLIISGGVGCAMVVGMGGSFLGLMMFLVYLGGMMVVFGYTTAMATEEYPEAWGSSKVIVGGVVLGV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1886411808  96 LAeILVLGWLFLGMNDGVYDVVMNGFDNNLVELGVgsglvrgdyvgssLLYGSGSWLLLISGWVLFVSIFIIIEI 170
Cdd:pfam00499  81 LL-LALLLLVLLSASLTPAAAAAAPDVGNIEAIGE-------------LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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