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Conserved domains on  [gi|1905532667|ref|NP_001373934|]
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NEDD4-binding protein 2-like 2 isoform 6 [Homo sapiens]

Protein Classification

ATP-binding protein( domain architecture ID 1004283)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AAA_33 super family cl38431
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 404-464 2.19e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


The actual alignment was detected with superfamily member pfam13671:

Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 39.60  E-value: 2.19e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1905532667  404 LILLRGLPGSGKTTLSRERVLKKTGHRLSkTKQKRNRKRNKKQNSQNRIMEENSL--EFLSDL 464
Cdd:pfam13671    1 LILLVGLPGSGKSTLARRLLEELGAVRLS-SDDERKRLFGEGRPSISYYTDATDRtyERLHEL 62
 
Name Accession Description Interval E-value
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 404-464 2.19e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 39.60  E-value: 2.19e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1905532667  404 LILLRGLPGSGKTTLSRERVLKKTGHRLSkTKQKRNRKRNKKQNSQNRIMEENSL--EFLSDL 464
Cdd:pfam13671    1 LILLVGLPGSGKSTLARRLLEELGAVRLS-SDDERKRLFGEGRPSISYYTDATDRtyERLHEL 62
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
404-421 4.81e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 39.13  E-value: 4.81e-03
                           10
                   ....*....|....*...
gi 1905532667  404 LILLRGLPGSGKTTLSRE 421
Cdd:COG0645      1 LILVCGLPGSGKSTLARA 18
 
Name Accession Description Interval E-value
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 404-464 2.19e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 39.60  E-value: 2.19e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1905532667  404 LILLRGLPGSGKTTLSRERVLKKTGHRLSkTKQKRNRKRNKKQNSQNRIMEENSL--EFLSDL 464
Cdd:pfam13671    1 LILLVGLPGSGKSTLARRLLEELGAVRLS-SDDERKRLFGEGRPSISYYTDATDRtyERLHEL 62
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
404-421 4.81e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 39.13  E-value: 4.81e-03
                           10
                   ....*....|....*...
gi 1905532667  404 LILLRGLPGSGKTTLSRE 421
Cdd:COG0645      1 LILVCGLPGSGKSTLARA 18
COG4639 COG4639
Predicted kinase [General function prediction only];
404-421 5.19e-03

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 38.66  E-value: 5.19e-03
                           10
                   ....*....|....*...
gi 1905532667  404 LILLRGLPGSGKTTLSRE 421
Cdd:COG4639      4 LVVLIGLPGSGKSTFARR 21
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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