|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
718-946 |
2.50e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
:
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.15 E-value: 2.50e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 718 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 797
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 798 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 877
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907117193 878 VKLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLRQSN 946
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRKNK 203
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1394-1523 |
1.12e-54 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
:
Pssm-ID: 211397 Cd Length: 134 Bit Score: 186.72 E-value: 1.12e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1394 EELRRQLEKLLKDGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQVLKVRARLLQKYLC-DEQ 1472
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDdDEQ 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1907117193 1473 KELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1523
Cdd:cd11559 84 LQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1195-1307 |
4.88e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
:
Pssm-ID: 397128 Cd Length: 113 Bit Score: 129.70 E-value: 4.88e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1195 VEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1274
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1907117193 1275 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1307
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| Herpes_BLLF1 super family |
cl37540 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
156-415 |
1.09e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
The actual alignment was detected with superfamily member pfam05109:
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 46.83 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 156 IMSGARTASTPTPPQTGGSLEPQPNGESPQVaviirpdDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEP 235
Cdd:pfam05109 404 IITRTATNATTTTHKVIFSKAPESTTTSPTL-------NTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSP 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 236 ---GSESNLGVLS---IPGDTMTTGMIPMSVEESTPISCETgePYCLSPEPTLAEPILE-VEVTLSKPIPESEFsSSPLQ 308
Cdd:pfam05109 477 tpaGTTSGASPVTpspSPRDNGTESKAPDMTSPTSAVTTPT--PNATSPTPAVTTPTPNaTSPTLGKTSPTSAV-TTPTP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 309 VSTALVPhKVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESlVPIAPTAQpeELLNGAPSPPAVDLSP---VSEP 385
Cdd:pfam05109 554 NATSPTP-AVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGET-SPQANTTN--HTLGGTSSTPVVTSPPknaTSAV 629
|
250 260 270
....*....|....*....|....*....|
gi 1907117193 386 EEQAKKVSSAALASiLSPAPPVAPSDTSPA 415
Cdd:pfam05109 630 TTGQHNITSSSTSS-MSLRPSSISETLSPS 658
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
2-523 |
2.14e-04 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 2 NTPSQPRQHFYPSRAQPPSSAASrvqSAAPARPGPAPHVYPAGSQvmmipsqisysasqgayyiPGQGRSTYVVPTQQYP 81
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLP---PDTHAPDPPPPSPSPAANE-------------------PDPHPPPTVPPPERPR 2653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 82 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQ--FPASVAPAPVLMNQPPQIAPKRERktirirdPNQGGKDITEEIMSG 159
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQASSPPQRPRRraARPTVGSLTSLADPPPPPPTPEPA-------PHALVSATPLPPGPA 2726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 160 ARTASTPTPPQTGGslePQPNGESPQVAVIIRPDDRSQGAAIGGRPGLP-GPEHSP--GTESQPSSPSPTPSPPPILEPG 236
Cdd:PHA03247 2727 AARQASPALPAAPA---PPAVPAGPATPGGPARPARPPTTAGPPAPAPPaAPAAGPprRLTRPAVASLSESRESLPSPWD 2803
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 237 SESNLGVLSIPGDTMTTGMIPMSVEESTPISCETgepyclsPEPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTALVPh 316
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT-------APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKP- 2875
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 317 KVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESLVPIAPTAQPEELLNGAPSP-----------PAVDLSPVSEP 385
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPpppprpqpplaPTTDPAGAGEP 2955
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 386 EEQAKKVSSAALASILSPA-----PPVAPSDTSPAQEEEMEEDDDDEEGGEAESEKGgedVPLDSTPVPAQLSQNLEVAA 460
Cdd:PHA03247 2956 SGAVPQPWLGALVPGRVAVprfrvPQPAPSREAPASSTPPLTGHSLSRVSSWASSLA---LHEETDPPPVSLKQTLWPPD 3032
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907117193 461 ATQVAvSVPKRRRKIKELNKKEAVgDLLDAFKEVDPAVPEVENQPPTGSNPSPESEGSMVPTQ 523
Cdd:PHA03247 3033 DTEDS-DADSLFDSDSERSDLEAL-DPLPPEPHDPFAHEPDPATPEAGARESPSSQFGPPPLS 3093
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
718-946 |
2.50e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.15 E-value: 2.50e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 718 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 797
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 798 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 877
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907117193 878 VKLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLRQSN 946
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRKNK 203
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1394-1523 |
1.12e-54 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 186.72 E-value: 1.12e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1394 EELRRQLEKLLKDGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQVLKVRARLLQKYLC-DEQ 1472
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDdDEQ 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1907117193 1473 KELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1523
Cdd:cd11559 84 LQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
719-946 |
7.36e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 184.10 E-value: 7.36e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 719 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 798
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 799 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 878
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907117193 879 KLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRQSN 946
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1195-1307 |
4.88e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 129.70 E-value: 4.88e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1195 VEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1274
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1907117193 1275 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1307
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1195-1307 |
2.62e-34 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 127.75 E-value: 2.62e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1195 VEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1274
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1907117193 1275 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1307
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1463-1545 |
2.00e-27 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 106.99 E-value: 2.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1463 LLQKYLCDEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFNWL 1542
Cdd:smart00515 3 LLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTWL 80
|
...
gi 1907117193 1543 REA 1545
Cdd:smart00515 81 QEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1474-1550 |
6.98e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 93.75 E-value: 6.98e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907117193 1474 ELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFNWLREAEDEES 1550
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
156-415 |
1.09e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 46.83 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 156 IMSGARTASTPTPPQTGGSLEPQPNGESPQVaviirpdDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEP 235
Cdd:pfam05109 404 IITRTATNATTTTHKVIFSKAPESTTTSPTL-------NTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSP 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 236 ---GSESNLGVLS---IPGDTMTTGMIPMSVEESTPISCETgePYCLSPEPTLAEPILE-VEVTLSKPIPESEFsSSPLQ 308
Cdd:pfam05109 477 tpaGTTSGASPVTpspSPRDNGTESKAPDMTSPTSAVTTPT--PNATSPTPAVTTPTPNaTSPTLGKTSPTSAV-TTPTP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 309 VSTALVPhKVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESlVPIAPTAQpeELLNGAPSPPAVDLSP---VSEP 385
Cdd:pfam05109 554 NATSPTP-AVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGET-SPQANTTN--HTLGGTSSTPVVTSPPknaTSAV 629
|
250 260 270
....*....|....*....|....*....|
gi 1907117193 386 EEQAKKVSSAALASiLSPAPPVAPSDTSPA 415
Cdd:pfam05109 630 TTGQHNITSSSTSS-MSLRPSSISETLSPS 658
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2-523 |
2.14e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 2 NTPSQPRQHFYPSRAQPPSSAASrvqSAAPARPGPAPHVYPAGSQvmmipsqisysasqgayyiPGQGRSTYVVPTQQYP 81
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLP---PDTHAPDPPPPSPSPAANE-------------------PDPHPPPTVPPPERPR 2653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 82 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQ--FPASVAPAPVLMNQPPQIAPKRERktirirdPNQGGKDITEEIMSG 159
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQASSPPQRPRRraARPTVGSLTSLADPPPPPPTPEPA-------PHALVSATPLPPGPA 2726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 160 ARTASTPTPPQTGGslePQPNGESPQVAVIIRPDDRSQGAAIGGRPGLP-GPEHSP--GTESQPSSPSPTPSPPPILEPG 236
Cdd:PHA03247 2727 AARQASPALPAAPA---PPAVPAGPATPGGPARPARPPTTAGPPAPAPPaAPAAGPprRLTRPAVASLSESRESLPSPWD 2803
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 237 SESNLGVLSIPGDTMTTGMIPMSVEESTPISCETgepyclsPEPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTALVPh 316
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT-------APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKP- 2875
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 317 KVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESLVPIAPTAQPEELLNGAPSP-----------PAVDLSPVSEP 385
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPpppprpqpplaPTTDPAGAGEP 2955
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 386 EEQAKKVSSAALASILSPA-----PPVAPSDTSPAQEEEMEEDDDDEEGGEAESEKGgedVPLDSTPVPAQLSQNLEVAA 460
Cdd:PHA03247 2956 SGAVPQPWLGALVPGRVAVprfrvPQPAPSREAPASSTPPLTGHSLSRVSSWASSLA---LHEETDPPPVSLKQTLWPPD 3032
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907117193 461 ATQVAvSVPKRRRKIKELNKKEAVgDLLDAFKEVDPAVPEVENQPPTGSNPSPESEGSMVPTQ 523
Cdd:PHA03247 3033 DTEDS-DADSLFDSDSERSDLEAL-DPLPPEPHDPFAHEPDPATPEAGARESPSSQFGPPPLS 3093
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
115-528 |
3.40e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.70 E-value: 3.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 115 PASVAPAPVLMNQPPQIAPK--------RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGgSLEPQPNGESPqv 186
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRpsepavtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTH-APDPPPPSPSP-- 2633
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 187 aviirpddRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLGVLSIPGDTMTTGMIPMSVEESTPi 266
Cdd:PHA03247 2634 --------AANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP- 2704
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 267 scetgEPyclSPEPTlaePILEVEVTLSKPIPESEFSSSPLQVSTALVPHKVETHEPNGVIPSEDLEPEVESSTEPAPPP 346
Cdd:PHA03247 2705 -----PP---TPEPA---PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 347 LSPCASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEeqakkvSSAALASILSPAPPVAPSDTS-PAQEEEMEEDDD 425
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA------PAAALPPAASPAGPLPPPTSAqPTAPPPPPGPPP 2847
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 426 DEEGGEAESEKGGedvPLDSTPVPAQlsqnlevAAATQVAVSVPKRRRKikelnKKEAVGDLLDAFKE-VDPAVPEVENQ 504
Cdd:PHA03247 2848 PSLPLGGSVAPGG---DVRRRPPSRS-------PAAKPAAPARPPVRRL-----ARPAVSRSTESFALpPDQPERPPQPQ 2912
|
410 420
....*....|....*....|....
gi 1907117193 505 PPTGSNPSPESEGSMVPTQPEETE 528
Cdd:PHA03247 2913 APPPPQPQPQPPPPPQPQPPPPPP 2936
|
|
| rad2 |
TIGR00600 |
DNA excision repair protein (rad2); All proteins in this family for which functions are known ... |
326-565 |
1.49e-03 |
|
DNA excision repair protein (rad2); All proteins in this family for which functions are known are flap endonucleases that generate the 3' incision next to DNA damage as part of nucleotide excision repair. This family is related to many other flap endonuclease families including the fen1 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273166 [Multi-domain] Cd Length: 1034 Bit Score: 43.35 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 326 VIPSEDlEPEVESSTEPAPPPLSpCASESLVPIAPTAQPEELLNG-APSPPAVDLSPVSepeeqakkvSSAALASILSPA 404
Cdd:TIGR00600 520 VKPVSS-EFGLPSQREDKLAIPT-EGTQNLQGISDHPEQFEFQNElSPLETKNNESNLS---------SDAETEGSPNPE 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 405 PPVAPSDTSPAQEEEMEEDDDDEeggeaesekGGEDV--PLDSTPVPAQLSQnlevaAATQVAVSVPKRRRKIkELNKKE 482
Cdd:TIGR00600 589 MPSWSSVTVPSEALDNYETTNPS---------NAKEVrnFAETGIQTTNVGE-----SADLLLISNPMEVEPM-ESEKEE 653
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 483 AVGDllDAFKEVDPAVPEVENQPPTGSNPSPESE-------GSMVPTQPEETEEtWDSKEDKIHNAENIQPGEQKYEYKS 555
Cdd:TIGR00600 654 SESD--GSFIEVDSVSSTLELQVPSKSQPTDESEenaenkvASIEGEHRKEIED-LLFDESEEDNIVGMIEEEKDADDFK 730
|
250
....*....|
gi 1907117193 556 DQWKPLNLEE 565
Cdd:TIGR00600 731 NEWQDISLEE 740
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
718-946 |
2.50e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.15 E-value: 2.50e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 718 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 797
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 798 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 877
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907117193 878 VKLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLRQSN 946
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRKNK 203
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1394-1523 |
1.12e-54 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 186.72 E-value: 1.12e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1394 EELRRQLEKLLKDGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQVLKVRARLLQKYLC-DEQ 1472
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDdDEQ 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1907117193 1473 KELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1523
Cdd:cd11559 84 LQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
719-946 |
7.36e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 184.10 E-value: 7.36e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 719 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 798
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 799 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 878
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907117193 879 KLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRQSN 946
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1195-1307 |
4.88e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 129.70 E-value: 4.88e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1195 VEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1274
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1907117193 1275 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1307
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1195-1307 |
2.62e-34 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 127.75 E-value: 2.62e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1195 VEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1274
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1907117193 1275 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1307
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1463-1545 |
2.00e-27 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 106.99 E-value: 2.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1463 LLQKYLCDEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFNWL 1542
Cdd:smart00515 3 LLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTWL 80
|
...
gi 1907117193 1543 REA 1545
Cdd:smart00515 81 QEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1474-1550 |
6.98e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 93.75 E-value: 6.98e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907117193 1474 ELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFNWLREAEDEES 1550
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| W2 |
cd11473 |
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of ... |
1394-1517 |
2.35e-19 |
|
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211395 Cd Length: 135 Bit Score: 85.61 E-value: 2.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1394 EELRRQLEKLLK-DGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFE----TPLRVDVQVLKVRARLLQKYL 1468
Cdd:cd11473 4 KKLRDSLLKELEeDKSSDVESVKAAKSKLDLDPISLEEVVKVLLTAVVNAVESADsislTQKEQLVLVLKKYGPVLRELL 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1907117193 1469 CD-EQKELQALYALQALVVT--LEQPANLLRMFFDALYDEDVVKEDAFYSWE 1517
Cdd:cd11473 84 KLiKKDQLYLLLKIEKLCLQlkLSELISLLEKILDLLYDADVLSEEAILSWF 135
|
|
| W2_eIF2B_epsilon |
cd11558 |
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a ... |
1463-1550 |
1.77e-13 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a heteropentameric complex which functions as a guanine nucleotide exchange factor in the recycling of eIF-2 during the initiation of translation in eukaryotes. The epsilon and gamma subunits are sequence similar and both are essential in yeast. Epsilon appears to be the catalytically active subunit, with gamma enhancing its activity. The C-terminal domain of the eIF2B epsilon subunit contains bipartite motifs rich in acidic and aromatic residues, which are responsible for the interaction with eIF2. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211396 Cd Length: 169 Bit Score: 69.98 E-value: 1.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1463 LLQKYLCDEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWL 1542
Cdd:cd11558 82 LLENYVKSQDDQVELLLALEEFCLESEEGGPLFAKLLHALYDLDILEEEAILEWWEEPDAGADEEMKKVRELVKKFIEWL 161
|
....*...
gi 1907117193 1543 REAEDEES 1550
Cdd:cd11558 162 EEAEEESD 169
|
|
| W2_eIF5 |
cd11561 |
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
1454-1550 |
4.47e-07 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211399 Cd Length: 157 Bit Score: 51.08 E-value: 4.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1454 VQVLKVRARLLQKYLCDEQKELQALYALQALVVtlEQPANLLRMF---FDALYDEDVVKEDAFYSW---ESSKDPAEQQG 1527
Cdd:cd11561 58 VKEIKKRKALLLKLVTDEKAQKALLGGIERFCG--KHSPELLKKVpliLKALYDNDILEEEVILKWyekVSKKYVSKEKS 135
|
90 100
....*....|....*....|...
gi 1907117193 1528 KGVaLKSVTAFFNWLREAEDEES 1550
Cdd:cd11561 136 KKV-RKAAEPFVEWLEEAEEEEE 157
|
|
| W2_eIF5C_like |
cd11560 |
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; ... |
1388-1548 |
2.81e-06 |
|
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211398 [Multi-domain] Cd Length: 194 Bit Score: 49.52 E-value: 2.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1388 QRTLAFEELRRQLEKLLKDGGSNQRVFDWIDANLNEQQIASN--------TLVRALMTTVCYSA---IIFETPLRVdvqv 1456
Cdd:cd11560 29 YRKQASQEIKKELQQELKEMIAEEEPVKEIIAAVKEQMKKSSlpehevvgLLWTALMDAVEWSKkedQIAEQALRH---- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 1457 LKVRARLLQKYLCDEQKELQALYALQalVVTLEQpANLLRMFFD---ALYDEDVVKEDAFYSWesSKDPAEQQGKGVALK 1533
Cdd:cd11560 105 LKKYAPLLAAFCTTARAELALLNKIQ--EYCYEN-MKFMKVFQKivkLLYKADVLSEDAILKW--YKKGHSPKGKQVFLK 179
|
170
....*....|....*
gi 1907117193 1534 SVTAFFNWLREAEDE 1548
Cdd:cd11560 180 QMEPFVEWLQEAEEE 194
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
156-415 |
1.09e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 46.83 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 156 IMSGARTASTPTPPQTGGSLEPQPNGESPQVaviirpdDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEP 235
Cdd:pfam05109 404 IITRTATNATTTTHKVIFSKAPESTTTSPTL-------NTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSP 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 236 ---GSESNLGVLS---IPGDTMTTGMIPMSVEESTPISCETgePYCLSPEPTLAEPILE-VEVTLSKPIPESEFsSSPLQ 308
Cdd:pfam05109 477 tpaGTTSGASPVTpspSPRDNGTESKAPDMTSPTSAVTTPT--PNATSPTPAVTTPTPNaTSPTLGKTSPTSAV-TTPTP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 309 VSTALVPhKVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESlVPIAPTAQpeELLNGAPSPPAVDLSP---VSEP 385
Cdd:pfam05109 554 NATSPTP-AVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGET-SPQANTTN--HTLGGTSSTPVVTSPPknaTSAV 629
|
250 260 270
....*....|....*....|....*....|
gi 1907117193 386 EEQAKKVSSAALASiLSPAPPVAPSDTSPA 415
Cdd:pfam05109 630 TTGQHNITSSSTSS-MSLRPSSISETLSPS 658
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2-523 |
2.14e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 2 NTPSQPRQHFYPSRAQPPSSAASrvqSAAPARPGPAPHVYPAGSQvmmipsqisysasqgayyiPGQGRSTYVVPTQQYP 81
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLP---PDTHAPDPPPPSPSPAANE-------------------PDPHPPPTVPPPERPR 2653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 82 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQ--FPASVAPAPVLMNQPPQIAPKRERktirirdPNQGGKDITEEIMSG 159
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQASSPPQRPRRraARPTVGSLTSLADPPPPPPTPEPA-------PHALVSATPLPPGPA 2726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 160 ARTASTPTPPQTGGslePQPNGESPQVAVIIRPDDRSQGAAIGGRPGLP-GPEHSP--GTESQPSSPSPTPSPPPILEPG 236
Cdd:PHA03247 2727 AARQASPALPAAPA---PPAVPAGPATPGGPARPARPPTTAGPPAPAPPaAPAAGPprRLTRPAVASLSESRESLPSPWD 2803
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 237 SESNLGVLSIPGDTMTTGMIPMSVEESTPISCETgepyclsPEPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTALVPh 316
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT-------APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKP- 2875
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 317 KVETHEPNGVIPSEDLEPEVESSTEPAPPPLSPCASESLVPIAPTAQPEELLNGAPSP-----------PAVDLSPVSEP 385
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPpppprpqpplaPTTDPAGAGEP 2955
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 386 EEQAKKVSSAALASILSPA-----PPVAPSDTSPAQEEEMEEDDDDEEGGEAESEKGgedVPLDSTPVPAQLSQNLEVAA 460
Cdd:PHA03247 2956 SGAVPQPWLGALVPGRVAVprfrvPQPAPSREAPASSTPPLTGHSLSRVSSWASSLA---LHEETDPPPVSLKQTLWPPD 3032
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907117193 461 ATQVAvSVPKRRRKIKELNKKEAVgDLLDAFKEVDPAVPEVENQPPTGSNPSPESEGSMVPTQ 523
Cdd:PHA03247 3033 DTEDS-DADSLFDSDSERSDLEAL-DPLPPEPHDPFAHEPDPATPEAGARESPSSQFGPPPLS 3093
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
115-528 |
3.40e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.70 E-value: 3.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 115 PASVAPAPVLMNQPPQIAPK--------RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGgSLEPQPNGESPqv 186
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRpsepavtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTH-APDPPPPSPSP-- 2633
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 187 aviirpddRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLGVLSIPGDTMTTGMIPMSVEESTPi 266
Cdd:PHA03247 2634 --------AANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP- 2704
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 267 scetgEPyclSPEPTlaePILEVEVTLSKPIPESEFSSSPLQVSTALVPHKVETHEPNGVIPSEDLEPEVESSTEPAPPP 346
Cdd:PHA03247 2705 -----PP---TPEPA---PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 347 LSPCASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEeqakkvSSAALASILSPAPPVAPSDTS-PAQEEEMEEDDD 425
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA------PAAALPPAASPAGPLPPPTSAqPTAPPPPPGPPP 2847
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 426 DEEGGEAESEKGGedvPLDSTPVPAQlsqnlevAAATQVAVSVPKRRRKikelnKKEAVGDLLDAFKE-VDPAVPEVENQ 504
Cdd:PHA03247 2848 PSLPLGGSVAPGG---DVRRRPPSRS-------PAAKPAAPARPPVRRL-----ARPAVSRSTESFALpPDQPERPPQPQ 2912
|
410 420
....*....|....*....|....
gi 1907117193 505 PPTGSNPSPESEGSMVPTQPEETE 528
Cdd:PHA03247 2913 APPPPQPQPQPPPPPQPQPPPPPP 2936
|
|
| rad2 |
TIGR00600 |
DNA excision repair protein (rad2); All proteins in this family for which functions are known ... |
326-565 |
1.49e-03 |
|
DNA excision repair protein (rad2); All proteins in this family for which functions are known are flap endonucleases that generate the 3' incision next to DNA damage as part of nucleotide excision repair. This family is related to many other flap endonuclease families including the fen1 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273166 [Multi-domain] Cd Length: 1034 Bit Score: 43.35 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 326 VIPSEDlEPEVESSTEPAPPPLSpCASESLVPIAPTAQPEELLNG-APSPPAVDLSPVSepeeqakkvSSAALASILSPA 404
Cdd:TIGR00600 520 VKPVSS-EFGLPSQREDKLAIPT-EGTQNLQGISDHPEQFEFQNElSPLETKNNESNLS---------SDAETEGSPNPE 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 405 PPVAPSDTSPAQEEEMEEDDDDEeggeaesekGGEDV--PLDSTPVPAQLSQnlevaAATQVAVSVPKRRRKIkELNKKE 482
Cdd:TIGR00600 589 MPSWSSVTVPSEALDNYETTNPS---------NAKEVrnFAETGIQTTNVGE-----SADLLLISNPMEVEPM-ESEKEE 653
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 483 AVGDllDAFKEVDPAVPEVENQPPTGSNPSPESE-------GSMVPTQPEETEEtWDSKEDKIHNAENIQPGEQKYEYKS 555
Cdd:TIGR00600 654 SESD--GSFIEVDSVSSTLELQVPSKSQPTDESEenaenkvASIEGEHRKEIED-LLFDESEEDNIVGMIEEEKDADDFK 730
|
250
....*....|
gi 1907117193 556 DQWKPLNLEE 565
Cdd:TIGR00600 731 NEWQDISLEE 740
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
280-440 |
3.21e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 42.00 E-value: 3.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 280 PTLAEPILEVEVTLSKPIPESEFSSSPLQV-STALVPHKVETHEPNGVIPSEDLEP---EVESSTEPAPPPLSPCASESL 355
Cdd:PRK08691 380 PSAQTAEKETAAKKPQPRPEAETAQTPVQTaSAAAMPSEGKTAGPVSNQENNDVPPwedAPDEAQTAAGTAQTSAKSIQT 459
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 356 VPIAPTAQPEEL-------------LNGAPSPPAVDLSPVSEPEEQAKKVSSAalasilsPAPPVA----PSDTSPAQEE 418
Cdd:PRK08691 460 ASEAETPPENQVsknkaadnetdapLSEVPSENPIQATPNDEAVETETFAHEA-------PAEPFYgygfPDNDCPPEDG 532
|
170 180
....*....|....*....|..
gi 1907117193 419 EMEEDDDDEEGGEAESEKGGED 440
Cdd:PRK08691 533 AEIPPPDWEHAAPADTAGGGAD 554
|
|
| Rib_recp_KP_reg |
pfam05104 |
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ... |
321-415 |
3.74e-03 |
|
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.
Pssm-ID: 461548 [Multi-domain] Cd Length: 140 Bit Score: 39.33 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 321 HEPNGVIPseDLEPEVESSTEPAPPPLSPCASESLVPIAPTAQPEELLNGAPSPPAVDlSPVSEPEEQAKKVSSAALAsi 400
Cdd:pfam05104 44 EKPNGKLP--ESEQADESEEEPREFKTPDEAPSAALEPEPVPTPVPAPVEPEPAPPSE-SPAPSPKEKKKKEKKSAKV-- 118
|
90
....*....|....*
gi 1907117193 401 lSPAPPVAPSDTSPA 415
Cdd:pfam05104 119 -EPAETPEAVQPKPA 132
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
299-415 |
4.59e-03 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 40.37 E-value: 4.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 299 ESEFSSSPLqvstalVPHKVETHEPNGV---------IPSEDLEPEVESSTEPAPPPLSPCASESLVPIAPTAQPEElln 369
Cdd:PRK11633 35 QDEFAAIPL------VPKPGDRDEPDMMpaatqalptQPPEGAAEAVRAGDAAAPSLDPATVAPPNTPVEPEPAPVE--- 105
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1907117193 370 gAPSPPavdlsPVSEPEEQAKKVSSAALASILSPAP-PVAPSDTSPA 415
Cdd:PRK11633 106 -PPKPK-----PVEKPKPKPKPQQKVEAPPAPKPEPkPVVEEKAAPT 146
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2-313 |
5.40e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 5.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 2 NTPSQPrqhfyPSRAQPPSSAASRVQSAAPARPGPAPHVYPAGSQVMMIPSQISYSASQGAYYIPGQGRSTYVVPTQQYP 81
Cdd:PHA03247 2755 ARPARP-----PTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 82 ----VQPGAPGFYPGASPTEFgTYAGAYYPAQGVQQFPASVAPAPVL----------MNQP-------PQIAPKRERKTI 140
Cdd:PHA03247 2830 pptsAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAKPaaparppvrrLARPavsrsteSFALPPDQPERP 2908
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 141 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGSLEPQPNGESPQVAVIIRPDDRSqGAAIGGR------------PGLP 208
Cdd:PHA03247 2909 PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWL-GALVPGRvavprfrvpqpaPSRE 2987
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 209 GPEHSPGTESQPSSPSPTPSPPPIL-----EPGSESNLGVLSIPGDtmTTGMIPMSVEESTPISCETGEPYCLSPEPTLA 283
Cdd:PHA03247 2988 APASSTPPLTGHSLSRVSSWASSLAlheetDPPPVSLKQTLWPPDD--TEDSDADSLFDSDSERSDLEALDPLPPEPHDP 3065
|
330 340 350
....*....|....*....|....*....|...
gi 1907117193 284 ---EPILEVEVTLSKPIPESEFSSSPLQVSTAL 313
Cdd:PHA03247 3066 fahEPDPATPEAGARESPSSQFGPPPLSANAAL 3098
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
91-514 |
6.29e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.29 E-value: 6.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 91 PGASPTEFGTYAGAYYPAQGVQQFPaSVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQ 170
Cdd:pfam03154 171 PPVLQAQSGAASPPSPPPPGTTQAA-TAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 171 TGGSLEPQPNGESPQVavIIRPDDRSQGAAiGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLgvlsiPGDT 250
Cdd:pfam03154 250 QPMTQPPPPSQVSPQP--LPQPSLHGQMPP-MPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAA-----PGQS 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 251 MTTGMIPMSVEESTPISCETGEPYCLSP------EPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTALVPhkvethePN 324
Cdd:pfam03154 322 QQRIHTPPSQSQLQSQQPPREQPLPPAPlsmphiKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPP-------PP 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 325 GVIPSEDLEPEVESSTEPAPPPLSPcASESLVPiaPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKKVSSAALAS-ILSP 403
Cdd:pfam03154 395 ALKPLSSLSTHHPPSAHPPPLQLMP-QSQQLPP--PPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPfVPGG 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117193 404 APPVAPSDTSPAQEEEMEEDDDDEEGGEAESekggedvpldSTPVPAqlsqnlevaaatQVAVSVPKRRRKIKELNKKEa 483
Cdd:pfam03154 472 PPPITPPSGPPTSTSSAMPGIQPPSSASVSS----------SGPVPA------------AVSCPLPPVQIKEEALDEAE- 528
|
410 420 430
....*....|....*....|....*....|.
gi 1907117193 484 vgdlldafkevdpavpEVENQPPTGSNPSPE 514
Cdd:pfam03154 529 ----------------EPESPPPPPRSPSPE 543
|
|
| |
