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Conserved domains on  [gi|1913506487|gb|QOG55579|]
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replicase [Porcine circovirus]

Protein Classification

replication-associated family protein( domain architecture ID 10261052)

replication-associated family protein similar to replication-associated protein and Para-Rep C1/7/9, both of which are ATP-dependent helicases

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 171-256 8.09e-26

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


:

Pssm-ID: 459992  Cd Length: 102  Bit Score: 98.45  E-value: 8.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913506487 171 VIVGPPGCGKSKWAANFAD---------PETTYWKPPRNKWWDGYHGEEVVVIDDFYGW---LPWDDLLRLCDRYPLTVE 238
Cdd:pfam00910   2 WLYGPPGCGKSTLAKYLARallkklglpKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPPP 81

                          90       100
                  ....*....|....*....|.
gi 1913506487 239 TKGG---TVPFLARSILITSN 256
Cdd:pfam00910  82 MAALeekGTPFTSKFVIVTSN 102
Viral_Rep super family cl03577
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 16-100 5.88e-16

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


The actual alignment was detected with superfamily member pfam02407:

Pssm-ID: 280553  Cd Length: 82  Bit Score: 71.44  E-value: 5.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913506487  16 RWVFTLNNPSEderkkirELPISLFD---YFIVGEEGNEEGrTPHLQGFANFVKKQTFNKVKWYFGARCHIEKAKGTDHQ 92
Cdd:pfam02407   3 CWCFTLNNPTE-------FLSLFSQDelkYFVYQDERGTTG-TKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEE 74


                  ....*...
gi 1913506487  93 NKEYCSKE 100
Cdd:pfam02407  75 ARDYCMKE 82
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 171-256 8.09e-26

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 98.45  E-value: 8.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913506487 171 VIVGPPGCGKSKWAANFAD---------PETTYWKPPRNKWWDGYHGEEVVVIDDFYGW---LPWDDLLRLCDRYPLTVE 238
Cdd:pfam00910   2 WLYGPPGCGKSTLAKYLARallkklglpKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPPP 81

                          90       100
                  ....*....|....*....|.
gi 1913506487 239 TKGG---TVPFLARSILITSN 256
Cdd:pfam00910  82 MAALeekGTPFTSKFVIVTSN 102
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 16-100 5.88e-16

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 71.44  E-value: 5.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913506487  16 RWVFTLNNPSEderkkirELPISLFD---YFIVGEEGNEEGrTPHLQGFANFVKKQTFNKVKWYFGARCHIEKAKGTDHQ 92
Cdd:pfam02407   3 CWCFTLNNPTE-------FLSLFSQDelkYFVYQDERGTTG-TKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEE 74


                  ....*...
gi 1913506487  93 NKEYCSKE 100
Cdd:pfam02407  75 ARDYCMKE 82
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 171-256 8.09e-26

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 98.45  E-value: 8.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913506487 171 VIVGPPGCGKSKWAANFAD---------PETTYWKPPRNKWWDGYHGEEVVVIDDFYGW---LPWDDLLRLCDRYPLTVE 238
Cdd:pfam00910   2 WLYGPPGCGKSTLAKYLARallkklglpKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPPP 81

                          90       100
                  ....*....|....*....|.
gi 1913506487 239 TKGG---TVPFLARSILITSN 256
Cdd:pfam00910  82 MAALeekGTPFTSKFVIVTSN 102
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 16-100 5.88e-16

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 71.44  E-value: 5.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913506487  16 RWVFTLNNPSEderkkirELPISLFD---YFIVGEEGNEEGrTPHLQGFANFVKKQTFNKVKWYFGARCHIEKAKGTDHQ 92
Cdd:pfam02407   3 CWCFTLNNPTE-------FLSLFSQDelkYFVYQDERGTTG-TKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEE 74


                  ....*...
gi 1913506487  93 NKEYCSKE 100
Cdd:pfam02407  75 ARDYCMKE 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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