|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
15-368 |
3.54e-119 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 349.35 E-value: 3.54e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 15 ILQVVPALVSGGVERGTIEVAKYLKILGHTPIIISAGGTLVKELDKEDIlhiEMNSSSKNPFVILNNAKLIAEIIKKYNV 94
Cdd:cd03819 1 ILMLTPALEIGGAETYILDLARALAERGHRVLVVTAGGPLLPRLRQIGI---GLPGLKVPLLRALLGNVRLARLIRRERI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 95 DIVHTRSRAPAWSSYLATKWTNAKFLTTFHGVYNIPNSFKKYYNSIMLKGEKVIAVSNFVKQHLLENYKIDEDKIVVIER 174
Cdd:cd03819 78 DLIHAHSRAPAWLGWLASRLTGVPLVTTVHGSYLATYHPKDFALAVRARGDRVIAVSELVRDHLIEALGVDPERIRVIPN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 175 GVNCDYFDPANLTPEklkkcRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKLKH-RDFYCLMVGDISRHPNFTNRVk 253
Cdd:cd03819 158 GVDTDRFPPEAEAEE-----RAQLGLPEGKPVVGYVGRLSPEKGWLLLVDAAAELKDePDFRLLVAGDGPERDEIRRLV- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 254 eliAALKLQNKIQIFGNDSDIINLYGISDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPNN 333
Cdd:cd03819 232 ---ERLGLRDRVTFTGFREDVPAALAASDVVVLPSLH-EEFGRVALEAMACGTPVVATDVGGAREIVVHGRTGLLVPPGD 307
|
330 340 350
....*....|....*....|....*....|....*...
gi 1962964333 334 AEALAEKIDYCfsILGTDTAKKIQEAA---RHTVINNF 368
Cdd:cd03819 308 AEALADAIRAA--KLLPEAREKLQAAAaltEAVRELLL 343
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
15-382 |
1.35e-59 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 197.38 E-value: 1.35e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 15 ILQVVPAL--VSGGVERGTIEVAKYLKILGHTPIIISAGGTLVKELDKEDILHIEMNsssKNPFVILNNAKLIAEI---I 89
Cdd:cd03801 2 ILLLSPELppPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLL---PSLAALLRARRLLRELrplL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 90 KKYNVDIVHTRSRAPAWSSYLATKWTNAKFLTTFHG--------VYNIPNSFKKYYNSIMLKGEKVIAVSNFVKQHLLEN 161
Cdd:cd03801 79 RLRKFDVVHAHGLLAALLAALLALLLGAPLVVTLHGaepgrlllLLAAERRLLARAEALLRRADAVIAVSEALRDELRAL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 162 YKIDEDKIVVIERGVNCDYFDPAnltpeklkkCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKLKHR--DFYCLMV 239
Cdd:cd03801 159 GGIPPEKIVVIPNGVDLERFSPP---------LRRKLGIPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRRgpDVRLVIV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 240 GdisRHPNFTNRVKELiaALKLQNKIQIFG--NDSDIINLYGISDIIVSASIePEAFGRTIIEGQAMEKLVIATNIGGAV 317
Cdd:cd03801 230 G---GDGPLRAELEEL--ELGLGDRVRFLGfvPDEELPALYAAADVFVLPSR-YEGFGLVVLEAMAAGLPVVATDVGGLP 303
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1962964333 318 ETINNNITGFHVEPNNAEALAEKIdyCFSILGTDTAKKIQEAARHTVINNFSLDLMLRKNLEVYK 382
Cdd:cd03801 304 EVVEDGEGGLVVPPDDVEALADAL--LRLLADPELRARLGRAARERVAERFSWERVAERLLDLYR 366
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
14-382 |
3.35e-47 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 164.80 E-value: 3.35e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 14 TILQVVPALVSGGVERGTIEVAKYLKILGHTPIIISAG--GTLVKELDKE--DILHIEMNSSsKNPFVILnnaKLIAeII 89
Cdd:cd03807 1 KVAHVITGLNVGGAETMLLRLLEHMDKSRFEHVVISLTgdGVLGEELLAAgvPVVCLGLSSG-KDPGVLL---RLAK-LI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 90 KKYNVDIVHTRSRAPAWSSYLATKW-TNAKFLTTFHGVyNIPNSFKKYYNSIMLKGEK----VIAVSNFVKQhLLENYKI 164
Cdd:cd03807 76 RKRNPDVVHTWMYHADLIGGLAAKLaGGVKVIWSVRSS-NIPQRLTRLVRKLCLLLSKfspaTVANSSAVAE-FHQEQGY 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 165 DEDKIVVIERGVNCDYFDPanlTPEKLKKCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKLK--HRDFYCLMVGDI 242
Cdd:cd03807 154 AKNKIVVIYNGIDLFKLSP---DDASRARARRRLGLAEDRRVIGIVGRLHPVKDHSDLLRAAALLVetHPDLRLLLVGRG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 243 SRHPNftnrVKELIAALKLQNKIQIFGNDSDIINLYGISDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIGGAVETINN 322
Cdd:cd03807 231 PERPN----LERLLLELGLEDRVHLLGERSDVPALLPAMDIFVLSSRT-EGFPNALLEAMACGLPVVATDVGGAAELVDD 305
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 323 NiTGFHVEPNNAEALAEKIDYCfsILGTDTAKKIQEAARHTVINNFSLDLMLRKNLEVYK 382
Cdd:cd03807 306 G-TGFLVPAGDPQALADAIRAL--LEDPEKRARLGRAARERIANEFSIDAMVRRYETLYY 362
|
|
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
21-376 |
9.48e-47 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 163.54 E-value: 9.48e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 21 ALVSGGVERGTIEVAKYLKILGHTPIIISA-GGTLVKELDKEDILH--IEMNSSSKNPFVILNNAKLIAEIIKKYNVDIV 97
Cdd:cd03808 6 VNVDGGFQSFRLPLIKALVKKGYEVHVIAPdGDKLSDELKELGVKVidIPILRRGINPLKDLKALFKLYKLLKKEKPDIV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 98 HTRSRAPA-WSSYLATKWTNAKFLTTFHGV--YNIPNSFKKY-----YNSIMLKGEKVIAVSNFVKQHLLENYKIDEDKI 169
Cdd:cd03808 86 HCHTPKPGiLGRLAARLAGVPKVIYTVHGLgfVFTEGKLLRLlylllEKLALLFTDKVIFVNEDDRDLAIKKGIIKKKKT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 170 VVIE-RGVNCDYFdpanltpeklkkCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKLKHR--DFYCLMVGDISRHp 246
Cdd:cd03808 166 VLIPgSGVDLDRF------------QYSPESLPSEKVVFLFVARLLKDKGIDELIEAAKILKKKgpNVRFLLVGDGELE- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 247 nftNRVKELIAALKLQNKIQIFGNDSDIINLYGISDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITG 326
Cdd:cd03808 233 ---NPSEILIEKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYR-EGLPRSLLEAMAAGRPVITTDVPGCRELVIDGVNG 308
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1962964333 327 FHVEPNNAEALAEKIDYCfsILGTDTAKKIQEAARHTVINNFSLDLMLRK 376
Cdd:cd03808 309 FLVPPGDVEALADAIEKL--IEDPELRKEMGEAARKRVEEKFDEEKVVNK 356
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
15-370 |
2.68e-38 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 140.57 E-value: 2.68e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 15 ILQVVPALVSGGVERGTIEVAKYLKILGH--TPIIISAGGTLVKELDKEDILHIEMNSSSKNPFVILNNAKL-IAEIIKK 91
Cdd:cd03811 2 ILFVIPSLSGGGAERVLLNLANALDKRGYdvTLVLLRDEGDLDKQLNGDVKLIRLLIRVLKLIKLGLLKAILkLKRILKR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 92 YNVDIVHT-RSRAPAWSSYLATKwtNAKFLTTFHGVYNI---PNSFKKYYNSIMLKGEKVIAVSNFVKQHLLENYKIDED 167
Cdd:cd03811 82 AKPDVVISfLGFATYIVAKLAAA--RSKVIAWIHSSLSKlyyLKKKLLLKLKLYKKADKIVCVSKGIKEDLIRLGPSPPE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 168 KIVVIERGVNCDYFdpanltpEKLKKCRDKYDaPSNVPIILMPSRMTSWKGHLVLVEALSKL--KHRDFYCLMVGDISRH 245
Cdd:cd03811 160 KIEVIYNPIDIDRI-------RALAKEPILNE-PEDGPVILAVGRLDPQKGHDLLIEAFAKLrkKYPDVKLVILGDGPLR 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 246 pnftNRVKELIAALKLQNKIQIFGNDSDIINLYGISDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIGGAVETINNNIT 325
Cdd:cd03811 232 ----EELEKLAKELGLAERVIFLGFQSNPYPYLKKADLFVLSSRY-EGFPNVLLEAMALGTPVVSTDCPGPREILDDGEN 306
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1962964333 326 GFHVEPNNAEALAEKIDYCFSILGTDTAKKIQEAARHTVINNFSL 370
Cdd:cd03811 307 GLLVPDGDAAALAGILAALLQKKLDAALRERLAKAQEAVFREYTI 351
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
205-362 |
2.89e-30 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 113.91 E-value: 2.89e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 205 PIILMPSRMTSWKGHLVLVEALSKLK--HRDFYCLMVGDisrhPNFTNRVKELIAALKLQNKIQIFG--NDSDIINLYGI 280
Cdd:pfam00534 3 KIILFVGRLEPEKGLDLLIKAFALLKekNPNLKLVIAGD----GEEEKRLKKLAEKLGLGDNVIFLGfvSDEDLPELLKI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 281 SDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKIDYCfsILGTDTAKKIQEAA 360
Cdd:pfam00534 79 ADVFVLPSRY-EGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNAEALAEAIDKL--LEDEELRERLGENA 155
|
..
gi 1962964333 361 RH 362
Cdd:pfam00534 156 RK 157
|
|
| Glyco_transf_4 |
pfam13439 |
Glycosyltransferase Family 4; |
25-179 |
3.87e-27 |
|
Glycosyltransferase Family 4;
Pssm-ID: 463877 [Multi-domain] Cd Length: 169 Bit Score: 105.69 E-value: 3.87e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 25 GGVERGTIEVAKYLKILGHTPIIIS--AGGTLVKELDKEDILHIEMNSSSKNPFVILNNAKLIAEIIKKYNVDIVHTRSR 102
Cdd:pfam13439 1 GGVERYVLELARALARRGHEVTVVTpgGPGPLAEEVVRVVRVPRVPLPLPPRLLRSLAFLRRLRRLLRRERPDVVHAHSP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 103 APAWSSYLATK-WTNAKFLTTFHGVYN-----------IPNSFKKYYNSIMLKGEKVIAVSNFVKQHLLENYKIDEDKIV 170
Cdd:pfam13439 81 FPLGLAALAARlRLGIPLVVTYHGLFPdykrlgarlspLRRLLRRLERRLLRRADRVIAVSEAVADELRRLYGVPPEKIR 160
|
....*....
gi 1962964333 171 VIERGVNCD 179
Cdd:pfam13439 161 VIPNGVDLE 169
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
15-341 |
5.18e-27 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 110.11 E-value: 5.18e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 15 ILQVV---PALVSGGVERGTIEVAKYLKILGHTPIIISAG---------GTLVKEL---DKEDILH-----IEMNSSSKN 74
Cdd:cd03823 2 ILLVNslyPPQRVGGAEISVHDLAEALVAEGHEVAVLTAGvgppgqatvARSVVRYrraPDETLPLalkrrGYELFETYN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 75 PFVilnnAKLIAEIIKKYNVDIVHTRS----RAPAWssYLATKwTNAKFLTTFHGVYNI-PNSFkkyynsiMLK--GEKV 147
Cdd:cd03823 82 PGL----RRLLARLLEDFRPDVVHTHNlsglGASLL--DAARD-LGIPVVHTLHDYWLLcPRQF-------LFKkgGDAV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 148 IAVSNFVKQHLLENYkIDEDKIVVIERGVNcdyFDPAnltpekLKKCRDKYDAPSNVPIIlmpSRMTSWKGHLVLVEALS 227
Cdd:cd03823 148 LAPSRFTANLHEANG-LFSARISVIPNAVE---PDLA------PPPRRRPGTERLRFGYI---GRLTEEKGIDLLVEAFK 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 228 KLKHRDFYCLMVGDISRHPnftnrvkelIAALKLQNKIQIFGN--DSDIINLYGISDIIVSASIEPEAFGRTIIEGQAME 305
Cdd:cd03823 215 RLPREDIELVIAGHGPLSD---------ERQIEGGRRIAFLGRvpTDDIKDFYEKIDVLVVPSIWPEPFGLVVREAIAAG 285
|
330 340 350
....*....|....*....|....*....|....*.
gi 1962964333 306 KLVIATNIGGAVETINNNITGFHVEPNNAEALAEKI 341
Cdd:cd03823 286 LPVIASDLGGIAELIQPGVNGLLFAPGDAEDLAAAM 321
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
75-384 |
6.09e-26 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 107.44 E-value: 6.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 75 PFVILNNAKLIAEIIKKYNVDIVHTRSRAP-AWSSYLATKWTNAKF--LTTFHG-----VYNIPnSFKKYYNSIMLKGEK 146
Cdd:cd04962 66 PPYTLALASKIVEVAKEHKLDVLHAHYAIPhASCAYLAREILGEKIpiVTTLHGtditlVGYDP-SLQPAVRFSINKSDR 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 147 VIAVSNFVKQHLLENYKIDEDkIVVIERGVNCDYFDPANLTPeklkkCRDKYDAPSNVPIILMPSRMTSWKG-------- 218
Cdd:cd04962 145 VTAVSSSLRQETYELFDVDKD-IEVIHNFIDEDVFKRKPAGA-----LKRRLLAPPDEKVVIHVSNFRPVKRiddvvrvf 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 219 HLVLVEALSKLkhrdfycLMVGDisrHPNFTNrVKELIAALKLQNKIQIFGNDSDIINLYGISDIIVSASiEPEAFGRTI 298
Cdd:cd04962 219 ARVRRKIPAKL-------LLVGD---GPERVP-AEELARELGVEDRVLFLGKQDDVEELLSIADLFLLPS-EKESFGLAA 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 299 IEGQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEkidYCFSILGTD-TAKKIQEAARHTVINNFSLDLMLRKN 377
Cdd:cd04962 287 LEAMACGVPVVSSNAGGIPEVVKHGETGFLSDVGDVDAMAK---SALSILEDDeLYNRMGRAARKRAAERFDPERIVPQY 363
|
....*..
gi 1962964333 378 LEVYKEI 384
Cdd:cd04962 364 EAYYRRL 370
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
89-346 |
1.33e-23 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 101.16 E-value: 1.33e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 89 IKKYNV--DIVHTRSRAPAWSSYLATKWTNAKFLTTFH--GVYNIPNSFKKYYNSIM--LKGEK-VIAVSNFV------- 154
Cdd:cd03800 95 IAREGGryDLIHSHYWDSGLVGALLARRLGVPLVHTFHslGRVKYRHLGAQDTYHPSlrITAEEqILEAADRViastpqe 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 155 KQHLLENYKIDEDKIVVIERGVNCDYFDP-----ANLTPEKLkkcrdkydaPSNVPIILMPSRMTSWKGHLVLVEALSKL 229
Cdd:cd03800 175 ADELISLYGADPSRINVVPPGVDLERFFPvdraeARRARLLL---------PPDKPVVLALGRLDPRKGIDTLVRAFAQL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 230 KHRDFYCLMV---GDI-SRHPNFTNRVKELIAALKLQNKIQIFG--NDSDIINLYGISDIIVSASIEpEAFGRTIIEGQA 303
Cdd:cd03800 246 PELRELANLVlvgGPSdDPLSMDREELAELAEELGLIDRVRFPGrvSRDDLPELYRAADVFVVPSLY-EPFGLTAIEAMA 324
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1962964333 304 MEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKIDYCFS 346
Cdd:cd03800 325 CGTPVVATAVGGLQDIVRDGRTGLLVDPHDPEALAAALRRLLD 367
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
82-384 |
1.69e-23 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 100.53 E-value: 1.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 82 AKLIAEIIKKYnVDIVHtrsRAPAWSS-YLATK---WTNAKFLTTFHG--VYNIPN--SFKKYYNSIMLKGEKVIAVSNF 153
Cdd:cd03798 85 AKLLKRRRRGP-PDLIH---AHFAYPAgFAAALlarLYGVPYVVTEHGsdINVFPPrsLLRKLLRWALRRAARVIAVSKA 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 154 VKQhLLENYKIDEDKIVVIERGVNCDYFDPANLTPeklkkcrdkyDAPSNVPIILMPSRMTSWKGHLVLVEALSKL--KH 231
Cdd:cd03798 161 LAE-ELVALGVPRDRVDVIPNGVDPARFQPEDRGL----------GLPLDAFVILFVGRLIPRKGIDLLLEAFARLakAR 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 232 RDFYCLMVGDISRHPnftnRVKELIAALKLQNKIQIFGN--DSDIINLYGISDIIVSASIEpEAFGRTIIEGQAMEKLVI 309
Cdd:cd03798 230 PDVVLLIVGDGPLRE----ALRALAEDLGLGDRVTFTGRlpHEQVPAYYRACDVFVLPSRH-EGFGLVLLEAMACGLPVV 304
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1962964333 310 ATNIGGAVETINNNITGFHVEPNNAEALAEKIDYcfsILGTDTAKKIQEAARHTVINNFSLDLMLRKNLEVYKEI 384
Cdd:cd03798 305 ATDVGGIPEVVGDPETGLLVPPGDADALAAALRR---ALAEPYLRELGEAARARVAERFSWVKAADRIAAAYRDV 376
|
|
| GT4_WfcD-like |
cd03795 |
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ... |
25-373 |
5.05e-23 |
|
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340826 [Multi-domain] Cd Length: 355 Bit Score: 98.89 E-value: 5.05e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 25 GGVERGTIEVAKYLKILGHTPIIISAGGTLVKELDKEDILHIEMNSSSKNPFVILNNAKLIAEIIKKY-NVDIVHTRSRA 103
Cdd:cd03795 14 GGIEQVIYDLAEGLKKKGIEVDVLCFSKEKETPEKEENGIRIHRVKSFLNVASTPFSPSYIKRFKKLAkEYDIIHYHFPN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 104 P------AWSSYlatkwtNAKFLTTFHGVYNIPNSFKKYYN---SIMLKGEKVIAVS--NFVKQ-HLLENYKideDKIVV 171
Cdd:cd03795 94 PladlllFFSGA------KKPVVVHWHSDIVKQKKLLKLYKplmTRFLRRADRIIATspNYVETsPTLREFK---NKVRV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 172 IERGVNCDYFDPANLTPEKLKKCRDKYdapsnvPIILMPSRMTSWKGHLVLVEALSKLkhrDFYCLMVGDisrhPNFTNR 251
Cdd:cd03795 165 IPLGIDKNVYNIPRVDFENIKREKKGK------KIFLFIGRLVYYKGLDYLIEAAQYL---NYPIVIGGE----GPLKPD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 252 VKELIAALKLQNkIQIFG--NDSDIINLYGISDIIVSASIE-PEAFGRTIIEGQAMEKLVIATNIGGAVETINNN-ITGF 327
Cdd:cd03795 232 LEAQIELNLLDN-VKFLGrvDDEEKVIYLHLCDVFVFPSVLrSEAFGIVLLEAMMCGKPVISTNIGTGVPYVNNNgETGL 310
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1962964333 328 HVEPNNAEALAEKIDycFSILGTDTAKKIQEAARHTVINNFSLDLM 373
Cdd:cd03795 311 VVPPKDPDALAEAID--KLLSDEELRESYGENAKKRFEELFTAEKM 354
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
205-341 |
2.79e-22 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 91.42 E-value: 2.79e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 205 PIILMPSRMTSW-KGHLVLVEALSKLKHRDFYC--LMVGDisrhpnftNRVKELIA-ALKLQNKIQIFGNDSDIINLYGI 280
Cdd:pfam13692 2 PVILFVGRLHPNvKGVDYLLEAVPLLRKRDNDVrlVIVGD--------GPEEELEElAAGLEDRVIFTGFVEDLAELLAA 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1962964333 281 SDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIGGAVETInNNITGFHVEPNNAEALAEKI 341
Cdd:pfam13692 74 ADVFVLPSLY-EGFGLKLLEAMAAGLPVVATDVGGIPELV-DGENGLLVPPGDPEALAEAI 132
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
21-341 |
7.07e-22 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 95.89 E-value: 7.07e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 21 ALVSGGVERGTIEVAKYLKILGHTPIIIsaggtLVKELDKEDILHIEMNSSSKNPFV-------ILNNAKLIAEIIKKYN 93
Cdd:cd03809 10 AQRLTGIGRYTRELLKALAKNDPDESVL-----AVPPLPGELLRLLREYPELSLGVIkiklwreLALLRWLQILLPKKDK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 94 VDIVH-TRSRAPAWSSylatkwtNAKFLTTFHGV------YNIPNSFKKYYNSIML----KGEKVIAVSNFVKQHLLENY 162
Cdd:cd03809 85 PDLLHsPHNTAPLLLK-------GCPQVVTIHDLiplrypEFFPKRFRLYYRLLLPislrRADAIITVSEATRDDIIKFY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 163 KIDEDKIVVIERGVNCDYFdpanlTPEKLKKCRDKYDAPSnvPIILMPSRMTSWKGHLVLVEALSKLK--HRDFYCLMVG 240
Cdd:cd03809 158 GVPPEKIVVIPLGVDPSFF-----PPESAAVLIAKYLLPE--PYFLYVGTLEPRKNHERLLKAFALLKkqGGDLKLVIVG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 241 diSRHPNFTNRVKeLIAALKLQNKIQIFGN--DSDIINLYGISDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIgGAVE 318
Cdd:cd03809 231 --GKGWEDEELLD-LVKKLGLGGRVRFLGYvsDEDLPALYRGARAFVFPSLY-EGFGLPVLEAMACGTPVIASNI-SVLP 305
|
330 340
....*....|....*....|...
gi 1962964333 319 TINNNiTGFHVEPNNAEALAEKI 341
Cdd:cd03809 306 EVAGD-AALYFDPLDPESIADAI 327
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
147-384 |
7.18e-22 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 95.86 E-value: 7.18e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 147 VIAVSNFVKQHLLENYKIDEDKIVVIERGVNCDYFDPANLtpeklKKCRDKYDAPSNVPIILMPSRMT--SWKGHLVLVE 224
Cdd:cd03825 141 IVAPSRWLADMVRRSPLLKGLPVVVIPNGIDTEIFAPVDK-----AKARKRLGIPQDKKVILFGAESVtkPRKGFDELIE 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 225 ALSKL-KHRDFYCLMVGDISrhpnftnrvkELIAALKLQnkIQIFG---NDSDIINLYGISDIIVSASIEpEAFGRTIIE 300
Cdd:cd03825 216 ALKLLaTKDDLLLVVFGKND----------PQIVILPFD--IISLGyidDDEQLVDIYSAADLFVHPSLA-DNLPNTLLE 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 301 GQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKIDYCfsILGTDTAKKIQEAARHTVINNFSLDLMLRKNLEV 380
Cdd:cd03825 283 AMACGTPVVAFDTGGSPEIVQHGVTGYLVPPGDVQALAEAIEWL--LANPKERESLGERARALAENHFDQRVQAQRYLEL 360
|
....
gi 1962964333 381 YKEI 384
Cdd:cd03825 361 YKDL 364
|
|
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
24-342 |
8.78e-22 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 95.38 E-value: 8.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 24 SGGVERGTIEVAKYLKILGHTPIIIS---AGGTLVKELDkEDILHIEMNSSSKNPF-VILNNAKLIA---EIIKKYNVDI 96
Cdd:cd03820 12 AGGAERVAINLANHLAKKGYDVTIISldsAEKPPFYELD-DNIKIKNLGDRKYSHFkLLLKYFKKVRrlrKYLKNNKPDV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 97 V---HTRSRapawsSYLATKWTNAKFLTTFHGVYNIPNSFKKYYNSIML---KGEKVIAVSNFVKqhlLENYKIDEDKIV 170
Cdd:cd03820 91 VisfRTSLL-----TFLALIGLKSKLIVWEHNNYEAYNKGLRRLLLRRLlykRADKIVVLTEADK---LKKYKQPNSNVV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 171 VIErgvN-CDYFDPANLTPEKLKkcrdkydapsnvpIILMPSRMTSWKGHLVLVEALSKL--KHRDFYCLMVGDISRHPN 247
Cdd:cd03820 163 VIP---NpLSFPSEEPSTNLKSK-------------RILAVGRLTYQKGFDLLIEAWALIakKHPDWKLRIYGDGPEREE 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 248 FtnrvKELIAALKLQNKIQIFGNDSDIINLYGISDIIVSASiEPEAFGRTIIEGQAMEKLVIATNI-GGAVETINNNITG 326
Cdd:cd03820 227 L----EKLIDKLGLEDRVKLLGPTKNIAEEYANSSIFVLSS-RYEGFPMVLLEAMAYGLPIISFDCpTGPSEIIEDGENG 301
|
330
....*....|....*.
gi 1962964333 327 FHVEPNNAEALAEKID 342
Cdd:cd03820 302 LLVPNGDVDALAEALL 317
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
277-386 |
9.23e-22 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 89.66 E-value: 9.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 277 LYGISDIIVSASIEpEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKIDYCFSIlgTDTAKKI 356
Cdd:COG0438 17 LLAAADVFVLPSRS-EGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLED--PELRRRL 93
|
90 100 110
....*....|....*....|....*....|
gi 1962964333 357 QEAARHTVINNFSLDLMLRKNLEVYKEILK 386
Cdd:COG0438 94 GEAARERAEERFSWEAIAERLLALYEELLA 123
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
15-381 |
1.62e-21 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 94.82 E-value: 1.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 15 ILQVVPALVSGGVERGTIEVAKYLKILGH-TPIIISAGGTLVKELDKEDILH-IEMnssSKNPFVILNNAKLIAEIIKKY 92
Cdd:cd04951 2 ILYVITGLGLGGAEKQTVLLADQMFIRGHdVNIVYLTGEVEVKPLNNNIIIYnLGM---DKNPRSLLKALLKLKKIISAF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 93 NVDIVHTRS-RAPAWSSYLATKWTNAKFLTTFHGVYNIPNSFKKYYNSIMLKGEKVIAVSNFVKQHLLENYKIDEDKIVV 171
Cdd:cd04951 79 KPDVVHSHMfHANIFARFLRMLYPIPLLICTAHNKNEGGRIRMFIYRLTDFLCDITTNVSREALDEFIAKKAFSKNKSVP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 172 IERGVNCDYFDpanLTPEKLKKCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKL--KHRDFYCLMVGDisrhPNFT 249
Cdd:cd04951 159 VYNGIDLNKFK---KDINVRLKIRNKLNLKNDEFVILNVGRLTEAKDYPNLLLAISELilSKNDFKLLIAGD----GPLR 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 250 NRVKELIAALKLQNKIQIFGNDSDIINLYGISDIIVSASiEPEAFGRTIIEGQAMEKLVIATNIGGAVETINNniTGFHV 329
Cdd:cd04951 232 NELERLICNLNLVDRVILLGQISNISEYYNAADLFVLSS-EWEGFGLVVAEAMACERPVVATDAGGVAEVVGD--HNYVV 308
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1962964333 330 EPNNAEALAEKIDYCFSIlgTDTAKKIQEAARHTVINNFSLDLMLRKNLEVY 381
Cdd:cd04951 309 PVSDPQLLAEKIKEIFDM--SDEERDILGNKNEYIAKNFSINTIVNEWERLY 358
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
35-342 |
7.17e-21 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 93.11 E-value: 7.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 35 AKYLKILGHTPIIIsagGTLVKELDKEDILHIEMNSS-----SKNPFVILNNAKLIAEIIKKYNVDIVHTRSR--APAWS 107
Cdd:cd03817 24 ARALEKRGHEVYVI---TPSDPGAEDEEEVVRYRSFSipirkYHRQHIPFPFKKAVIDRIKELGPDIIHTHTPfsLGKLG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 108 SYLATKWtNAKFLTTFHGVY-----NIPNSF-----------KKYYNsimlKGEKVIAVSNFVKQhLLENYKIDeDKIVV 171
Cdd:cd03817 101 LRIARKL-KIPIVHTYHTMYedylhYIPKGKllvkavvrklvRRFYN----HTDAVIAPSEKIKD-TLREYGVK-GPIEV 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 172 IERGVNCDYFDPanltpEKLKKCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKLKHR-DFYCLMVGDISRHPNFtn 250
Cdd:cd03817 174 IPNGIDLDKFEK-----PLNTEERRKLGLPPDEPILLYVGRLAKEKNIDFLLRAFAELKKEpNIKLVIVGDGPEREEL-- 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 251 rvKELIAALKLQNKIQIFG--NDSDIINLYGISDIIVSASiEPEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFH 328
Cdd:cd03817 247 --KELARELGLADKVIFTGfvPREELPEYYKAADLFVFAS-TTETQGLVYLEAMAAGLPVVAAKDPAASELVEDGENGFL 323
|
330
....*....|....
gi 1962964333 329 VEPNNaEALAEKID 342
Cdd:cd03817 324 FEPND-ETLAEKLL 336
|
|
| GT4_AmsK-like |
cd03799 |
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ... |
61-343 |
1.91e-19 |
|
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.
Pssm-ID: 340829 [Multi-domain] Cd Length: 350 Bit Score: 88.66 E-value: 1.91e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 61 EDILH---IEMNSSSKNPFVILNNAkliaeiIKKYNVDIVHTR---SRAPAwSSYLATKWTNAKFLTTFHGvYNIPNSFK 134
Cdd:cd03799 41 LVKRHpdvEKYNVPSLNLLYAIVGL------NKKGAYDIIHCQfgpLGALG-ALLRRLKVLKGKLVTSFRG-YDISMYVI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 135 KY----YNSIMLKGEKVIAVSNFVKQHLLeNYKIDEDKIVVIERGVNCDYFdpaNLTPEKLkkcrdkydaPSNVPI-ILM 209
Cdd:cd03799 113 LEgnkvYPQLFAQGDLFLPNCELFKHRLI-ALGCDEKKIIVHRSGIDCNKF---RFKPRYL---------PLDGKIrILT 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 210 PSRMTSWKGHLVLVEALSKL--KHRDFYCLMVGDISRHpnftNRVKELIAALKLQNKIQIFG--NDSDIINLYGISDIIV 285
Cdd:cd03799 180 VGRLTEKKGLEYAIEAVAKLaqKYPNIEYQIIGDGDLK----EQLQQLIQELNIGDCVKLLGwkPQEEIIEILDEADIFI 255
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1962964333 286 SASI-----EPEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKIDY 343
Cdd:cd03799 256 APSVtaadgDQDGPPNTLKEAMAMGLPVISTEHGGIPELVEDGVSGFLVPERDAEAIAEKLTY 318
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
168-329 |
4.08e-16 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 77.06 E-value: 4.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 168 KIVVIERGVNC-DYFDPANLTPEKLKKCRDKYDApsnvpiiLMPSRMTSWKGHLVLVEALSKLKHR--DFYCLMVGDISR 244
Cdd:cd01635 80 PIVVTVHGPDSlESTRSELLALARLLVSLPLADK-------VSVGRLVPEKGIDLLLEALALLKARlpDLVLVLVGGGGE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 245 HPnftnRVKELIAALKLQNKIQIFGN---DSDIINLYGISDIIVSASIePEAFGRTIIEGQAMEKLVIATNIGGAVETIN 321
Cdd:cd01635 153 RE----EEEALAAALGLLERVVIIGGlvdDEVLELLLAAADVFVLPSR-SEGFGLVLLEAMAAGKPVIATDVGGIPEFVV 227
|
....*...
gi 1962964333 322 NNITGFHV 329
Cdd:cd01635 228 DGENGLLV 235
|
|
| PRK15484 |
PRK15484 |
lipopolysaccharide N-acetylglucosaminyltransferase; |
78-371 |
7.67e-14 |
|
lipopolysaccharide N-acetylglucosaminyltransferase;
Pssm-ID: 185381 [Multi-domain] Cd Length: 380 Bit Score: 72.13 E-value: 7.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 78 ILNNAKLIAeiIKKYNVDIVHT--------RSRAPawssylatkwtNAKFLTTFHgvynipNSFKKyynSIMLKGEKVIA 149
Cdd:PRK15484 88 ILNIAHKFT--ITKDSVIVIHNsmklyrqiRERAP-----------QAKLVMHMH------NAFEP---ELLDKNAKIIV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 150 VSNFVKQHLlENYKIDEDkIVVIERGvncdyFDPANLTPEKLKKCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKL 229
Cdd:PRK15484 146 PSQFLKKFY-EERLPNAD-ISIVPNG-----FCLETYQSNPQPNLRQQLNISPDETVLLYAGRISPDKGILLLMQAFEKL 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 230 --KHRDFYCLMVGDI-----SRHPNFTNRVKELIAALKLQNkIQIFGNDSDII-NLYGISDIIVSASIEPEAFGRTIIEG 301
Cdd:PRK15484 219 atAHSNLKLVVVGDPtasskGEKAAYQKKVLEAAKRIGDRC-IMLGGQPPEKMhNYYPLADLVVVPSQVEEAFCMVAVEA 297
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1962964333 302 QAMEKLVIATNIGGAVETINNNITGFHV-EPNNAEALAEKIDycfSILGTDTAKKIQEAARHTVINNFSLD 371
Cdd:PRK15484 298 MAAGKPVLASTKGGITEFVLEGITGYHLaEPMTSDSIISDIN---RTLADPELTQIAEQAKDFVFSKYSWE 365
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
24-376 |
5.62e-13 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 69.68 E-value: 5.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 24 SGGVERGTIEVAKYLKILGHTPIIISAG---------GTLVKELDKEDILHIEMNSSSKNPFVILNN---------AKLI 85
Cdd:cd03794 13 KGAAAARVYELAKELVRRGHEVTVLTPSpnyplgrifAGATETKDGIRVIRVKLGPIKKNGLIRRLLnylsfalaaLLKL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 86 AEIIKKYNVDIVHTRSRAPAWSSYLATKWTNAKFLTTFHGVYniPNSF-------KKYYNSIMLKGEK--------VIAV 150
Cdd:cd03794 93 LVREERPDVIIAYSPPITLGLAALLLKKLRGAPFILDVRDLW--PESLialgvlkKGSLLKLLKKLERklyrladaIIVL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 151 SNFVKQHLLENYkIDEDKIVVIERGVNCDYFDPANLTPEKLKKCRDKydapsnvPIILMPSR-MTSWKGHLVLVEALSKL 229
Cdd:cd03794 171 SPGLKEYLLRKG-VPKEKIIVIPNWADLEEFKPPPKDELRKKLGLDD-------KFVVVYAGnIGKAQGLETLLEAAERL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 230 KHRDFYCLM-VGDISRHPnftnRVKELIAALKLQNkIQIFG--NDSDIINLYGISDIIVsASIEPEAFGRTIIEGQ---- 302
Cdd:cd03794 243 KRRPDIRFLfVGDGDEKE----RLKELAKARGLDN-VTFLGrvPKEEVPELLSAADVGL-VPLKDNPANRGSSPSKlfey 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1962964333 303 -AMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKIDYCfsILGTDTAKKIQEAARHTVINNFSLDLMLRK 376
Cdd:cd03794 317 mAAGKPILASDDGGSDLAVEINGCGLVVEPGDPEALADAILEL--LDDPELRRAMGENGRELAEEKFSREKLADR 389
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
94-382 |
1.88e-12 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 68.52 E-value: 1.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 94 VDIVHTRSRAPA-WSSYLATKWTNAKFLTTFHGVY------NIPNSF--KKYYNSIMLK------------GEKVIAVSN 152
Cdd:cd03813 174 ADLYHSVSTGYAgLLGALARHRRGIPFLLTEHGIYtrerkiEILQSTwiMGYIKKLWIRfferlgklayqqADKIISLYE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 153 FVKQHLLEnYKIDEDKIVVIERGVNCDYFDPANLTPEKlkkcrdkydapSNVPIILMPSRMTSWKGHLVLVEALSKLKHR 232
Cdd:cd03813 254 GNRRRQIR-LGADPDKTRVIPNGIDIQRFAPAREERPE-----------KEPPVVGLVGRVVPIKDVKTFIRAFKLVRRA 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 233 --DFYCLMVGDISRHPNFTNRVKELIAALKLQNKIQIFGNDsDIINLYGISDIIVSASIEpEAFGRTIIEGQAMEKLVIA 310
Cdd:cd03813 322 mpDAEGWLIGPEDEDPEYAQECKRLVASLGLENKVKFLGFQ-NIKEYYPKLGLLVLTSIS-EGQPLVILEAMASGVPVVA 399
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1962964333 311 TNIGGAVETI-----NNNITGFHVEPNNAEALAEKIDYcfsiLGTDTAK--KIQEAARHTVINNFSLDLMLRKNLEVYK 382
Cdd:cd03813 400 TDVGSCRELIygaddALGQAGLVVPPADPEALAEALIK----LLRDPELrqAFGEAGRKRVEKYYTLEGMIDSYRKLYL 474
|
|
| GT4_ALG2-like |
cd03805 |
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ... |
148-373 |
2.91e-11 |
|
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.
Pssm-ID: 340834 [Multi-domain] Cd Length: 392 Bit Score: 64.53 E-value: 2.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 148 IAV-SNFVKQHLLENYKIDEDKIV-VIERGVNCDYFDPAnltpEKLKKCRDKyDAPSNVPIILMPSRMTSWKGHLVLVEA 225
Cdd:cd03805 158 IVVnSNFTAGVFKKTFPSLAKNPPeVLYPCVDTDSFDST----SEDPDPGDL-IAKSNKKFFLSINRFERKKNIALAIEA 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 226 LSKLK--HRDFYCLMV----GdisrhpnFTNRVKELIAALK-LQNKIQIFGNDSD-IINLYGISD----IIVSASI---- 289
Cdd:cd03805 233 FAKLKqkLPEFENVRLviagG-------YDPRVAENVEYLEeLQRLAEELLNVEDqVLFLRSISDsqkeQLLSSALally 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 290 --EPEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPnNAEALAEKIDYCFSilGTDTAKKIQEAARHTVINN 367
Cdd:cd03805 306 tpSNEHFGIVPLEAMYAGKPVIACNSGGPLETVVEGVTGFLCEP-TPEAFAEAMLKLAN--DPDLADRMGAAGRKRVKEK 382
|
....*.
gi 1962964333 368 FSLDLM 373
Cdd:cd03805 383 FSREAF 388
|
|
| GT4-like |
cd05844 |
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ... |
120-372 |
5.42e-11 |
|
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340860 [Multi-domain] Cd Length: 365 Bit Score: 63.63 E-value: 5.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 120 LTTFHGvYNI-------------PNSFKKYYNSIMLKGEKVIAVSNFVKQHLLENyKIDEDKIVVIERGVNCDYFDPAnl 186
Cdd:cd05844 108 VVTFHG-FDIttsrawlaaspgwPSQFQRHRRALQRPAALFVAVSGFIRDRLLAR-GLPAERIHVHYIGIDPAKFAPR-- 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 187 tpeklkkcrdkyDAPSNVPIILMPSRMTSWKGHLVLVEALSKLKHR--DFYCLMVGDISrhpnFTNRVKELIAALklqNK 264
Cdd:cd05844 184 ------------DPAERAPTILFVGRLVEKKGCDVLIEAFRRLAARhpTARLVIAGDGP----LRPALQALAAAL---GR 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 265 IQIFGNDS--DIINLYGISDI-----IVSASIEPEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEAL 337
Cdd:cd05844 245 VRFLGALPhaEVQDWMRRAEIfclpsVTAASGDSEGLGIVLLEAAACGVPVVSSRHGGIPEAILDGETGFLVPEGDVDAL 324
|
250 260 270
....*....|....*....|....*....|....*.
gi 1962964333 338 AEKIDycfSILGTDT-AKKIQEAARHTVINNFSLDL 372
Cdd:cd05844 325 ADALQ---ALLADRAlADRMGGAARAFVCEQFDIRV 357
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
165-364 |
1.65e-08 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 55.84 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 165 DEDKIVVIERGVNCDYFDPANLTPEKLKKCRDKydapsnvPIILMPSRMTSWKGHLVLVEALSKL--KHRDFYCLMVG-D 241
Cdd:cd03821 172 LEPPIAVIPNGVDIPEFDPGLRDRRKHNGLEDR-------RIILFLGRIHPKKGLDLLIRAARKLaeQGRDWHLVIAGpD 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 242 ISRHPNFtnrvKELIAALKLQNKIQIFG--NDSDIINLYGISDIIVSASiEPEAFGRTIIEGQAME-KLVIATNIGGAVE 318
Cdd:cd03821 245 DGAYPAF----LQLQSSLGLGDRVTFTGplYGEAKWALYASADLFVLPS-YSENFGNVVAEALACGlPVVITDKCGLSEL 319
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1962964333 319 TINNNitGFHVEPNN---AEALAEKIDYcfsilgTDTAKKIQEAARHTV 364
Cdd:cd03821 320 VEAGC--GVVVDPNVsslAEALAEALRD------PADRKRLGEMARRAR 360
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
133-345 |
6.63e-08 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 53.84 E-value: 6.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 133 FKKYYNSIM--LKGEKVIAVSNFVKQHLLENYKIDEDKIVVIERGvncdyFDPANLTPEKLKKcRDKYdapsnvpIILMP 210
Cdd:cd04949 100 IKNFYKYVFenLNKYDAIIVSTEQQKQDLSERFNKYPPIFTIPVG-----YVDQLDTAESNHE-RKSN-------KIITI 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 211 SRMTSWKGHLVLVEALSKLKHR------DFYCLmvGDISRHPnftnrvKELIAALKLQNKIQIFGNDSDIINLYGISDII 284
Cdd:cd04949 167 SRLAPEKQLDHLIEAVAKAVKKvpeitlDIYGY--GEEREKL------KKLIEELHLEDNVFLKGYHSNLDQEYQDAYLS 238
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1962964333 285 VSASiEPEAFGRTIIEGQAMEKLVIATNIG-GAVETINNNITGFHVEPNNAEALAEKIDYCF 345
Cdd:cd04949 239 LLTS-QMEGFGLTLMEAIGHGLPVVSYDVKyGPSELIEDGENGYLIEKNNIDALADKIIELL 299
|
|
| GT4_mannosyltransferase-like |
cd03822 |
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ... |
118-342 |
2.81e-07 |
|
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.
Pssm-ID: 340849 [Multi-domain] Cd Length: 370 Bit Score: 52.00 E-value: 2.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 118 KFLTTFHGVYNIPNSFKKYYNSIMLKGEKVIAVsnFVKQHLLEN-----YKIDEDKIVVIERGVNCDYFDPanltpeklK 192
Cdd:cd03822 106 PVITTLHTVLDLSDPGKQALKVLFRIATLSERV--VVMAPISRFllvriKLIPAVNIEVIPHGVPEVPQDP--------T 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 193 KCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKLK--HRDFYCLMVG----DISRHPNFTNRVKElIAALKLQNKIQ 266
Cdd:cd03822 176 TALKRLLLPEGKKVILTFGFIGPGKGLEILLEALPELKaeFPDVRLVIAGelhpSLARYEGERYRKAA-IEELGLQDHVD 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 267 I---FGNDSDIINLYGISDIIVSA--SIEPEAFGrTIIEGQAMEKLVIATNIGGAVEtINNNITGFHVEPNNAEALAEKI 341
Cdd:cd03822 255 FhnnFLPEEEVPRYISAADVVVLPylNTEQSSSG-TLSYAIACGKPVISTPLRHAEE-LLADGRGVLVPFDDPSAIAEAI 332
|
.
gi 1962964333 342 D 342
Cdd:cd03822 333 L 333
|
|
| GT4_CapH-like |
cd03812 |
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ... |
15-346 |
4.95e-07 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).
Pssm-ID: 340840 [Multi-domain] Cd Length: 357 Bit Score: 51.14 E-value: 4.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 15 ILQVVPALVSGGVERGTIEVAKYLKILGHTPIIISAggTLVKELDKEDI--LHIEMNSSSKNPFVILNNAKLIAEIIKKY 92
Cdd:cd03812 2 ILHIVGGMNVGGIETFLMNLYRKLDKSKIEFDFLAT--SDDKGEYDEELeeLGGKIFYIPPKKKNIIKYFIKLLKLIKKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 93 NVDIVHTRS----RAPAWSSYLA-----------TKWTNAKFLTTFHGVYNIPnsFKKYYNsimlkgeKVIAVSNFVKQH 157
Cdd:cd03812 80 KYDIVHVHGsssnGIILLLAAKAgvpvriahshnTKDSSIKLRKIRKNVLKKL--IERLST-------KYLACSEDAGEW 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 158 LLEnyKIDEDKIVVIERGVNCDYFDPanltPEKLKKCRDKYDAPSNVPIILMPSRMTSWKGHLVLVEALSKLKHR--DFY 235
Cdd:cd03812 151 LFG--EVENGKFKVIPNGIDIEKYKF----NKEKRRKRRKLLILEDKLVLGHVGRFNEQKNHSFLIDIFEELKKKnpNVK 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 236 CLMVGDISrhpnFTNRVKELIAALKLQNKIQIFGNDSDIINLYGISDIIVSASiEPEAFGRTIIEGQAMEKLVIATNIGG 315
Cdd:cd03812 225 LVLVGEGE----LKEKIKEKVKELGLEDKVIFLGFRNDVSEILSAMDVFLFPS-LYEGLPLVAVEAQASGLPCLLSDTIT 299
|
330 340 350
....*....|....*....|....*....|.
gi 1962964333 316 AVETINNNITGFHVEpNNAEALAEKIDYCFS 346
Cdd:cd03812 300 KECDITNNVEFLPLN-ETPSTWAEKILKLIK 329
|
|
| GT4_trehalose_phosphorylase |
cd03792 |
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ... |
205-368 |
5.60e-07 |
|
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.
Pssm-ID: 340823 [Multi-domain] Cd Length: 378 Bit Score: 51.17 E-value: 5.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 205 PIILMPSRMTSWKGHLVLVEALSKLKHRDFYCLMVgdISRHPNftnrVKELIAALKLQNKIQIFGNDSDI---------- 274
Cdd:cd03792 198 PYILQVARFDPSKDPLGVIDAYKLFKRRAEEPQLV--ICGHGA----VDDPEGSVVYEEVMEYAGDDHDIhvlrlppsdq 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 275 -IN-LYGISDIIVSASIePEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALaekidyCFSILGTDT 352
Cdd:cd03792 272 eINaLQRAATVVLQLST-REGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGFLVNSVEGAAV------RILRLLTDP 344
|
170
....*....|....*...
gi 1962964333 353 A--KKIQEAARHTVINNF 368
Cdd:cd03792 345 ElrRKMGLAAREHVRDNF 362
|
|
| PRK15179 |
PRK15179 |
Vi polysaccharide biosynthesis protein TviE; Provisional |
130-382 |
2.36e-06 |
|
Vi polysaccharide biosynthesis protein TviE; Provisional
Pssm-ID: 185101 [Multi-domain] Cd Length: 694 Bit Score: 49.65 E-value: 2.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 130 PNSFKKYYNSI---MLKGEKVIAVSNFVK--QHLLENYKIDEDKIVVIERGVncdyfdpANLTPEKLKKCRDKY------ 198
Cdd:PRK15179 440 PDRYRVEYDIIyseLLKMRGVALSSNSQFaaHRYADWLGVDERRIPVVYNGL-------APLKSVQDDACTAMMaqfdar 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 199 --DAPSNVPIILmpsRMTSWKGHLVLVEALSKL--KHRDFYCLMVGDISRHPNftnrVKELIAALKLQNKIQIFGNDSDI 274
Cdd:PRK15179 513 tsDARFTVGTVM---RVDDNKRPFLWVEAAQRFaaSHPKVRFIMVGGGPLLES----VREFAQRLGMGERILFTGLSRRV 585
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 275 INLYGISDIIVSASiEPEAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHV------EPNNAEALAEKIDYCfsil 348
Cdd:PRK15179 586 GYWLTQFNAFLLLS-RFEGLPNVLIEAQFSGVPVVTTLAGGAGEAVQEGVTGLTLpadtvtAPDVAEALARIHDMC---- 660
|
250 260 270
....*....|....*....|....*....|....
gi 1962964333 349 GTDTAkkIQEAARHTVINNFSLDLMLRKNLEVYK 382
Cdd:PRK15179 661 AADPG--IARKAADWASARFSLNQMIASTVRCYQ 692
|
|
| PLN00142 |
PLN00142 |
sucrose synthase |
292-341 |
3.70e-06 |
|
sucrose synthase
Pssm-ID: 215073 [Multi-domain] Cd Length: 815 Bit Score: 49.21 E-value: 3.70e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1962964333 292 EAFGRTIIEGQAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKI 341
Cdd:PLN00142 677 EAFGLTVVEAMTCGLPTFATCQGGPAEIIVDGVSGFHIDPYHGDEAANKI 726
|
|
| GT4_AviGT4-like |
cd03802 |
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ... |
15-384 |
8.45e-06 |
|
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.
Pssm-ID: 340832 [Multi-domain] Cd Length: 333 Bit Score: 47.28 E-value: 8.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 15 ILQVVPALVS------GGVERGTIEVAKYLKILGHTPIIISAGG--------TLVKELDKEDILHIEmnSSSKNPFVILn 80
Cdd:cd03802 2 IAQVSPPRGPvppgkyGGTELVVSALTEGLVRRGHEVTLFAPGDshtsaplvAVIPRALRLDPIPQE--SKLAELLEAL- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 81 nakliAEIIKKYNVDIVHTRS--RAPAWSSYLATKwtnakFLTTFHGVYNIPNSFKKYYNSIMLkgekVIAVSNFVKQHL 158
Cdd:cd03802 79 -----EVQLRASDFDVIHNHSydWLPPFAPLIGTP-----FVTTLHGPSIPPSLAIYAAEPPVN----YVSISDAQRAAT 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 159 LenykiDEDKIVVIERGVNCDYFDPANLTPEKLkkcrdkydapsnvpiiLMPSRMTSWKGHLVLVEALSKLKHRdfyCLM 238
Cdd:cd03802 145 P-----PIDYLTVVHNGLDPADYRFQPDPEDYL----------------AFLGRIAPEKGLEDAIRVARRAGLP---LKI 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 239 VGDISRHPNFtnrvkELIAALKLQNKIQIFG--NDSDIINLYGISDIIVSASIEPEAFGRTIIEGQAMEKLVIATNIGGA 316
Cdd:cd03802 201 AGKVRDEDYF-----YYLQEPLPGPRIEFIGevGHDEKQELLGGARALLFPINWDEPFGLVMIEAMACGTPVIAYRRGGL 275
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1962964333 317 VETINNNITGFHVEPnnAEALAEkidycfSILGTDTAKKiqEAARHTVINNFSLDLMLRKNLEVYKEI 384
Cdd:cd03802 276 PEVIQHGETGFLVDS--VEEMAE------AIANIDRIDR--AACRRYAEDRFSAARMADRYEALYRKV 333
|
|
| GT4_WbaZ-like |
cd03804 |
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ... |
146-344 |
1.41e-04 |
|
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.
Pssm-ID: 340833 [Multi-domain] Cd Length: 356 Bit Score: 43.43 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 146 KVIAVSNFVKQHLLENYKIDEdkiVVIERGVNCDYFDPANltpeklkkCRDKYdapsnvpiILMPSRMTSWKGHLVLVEA 225
Cdd:cd03804 160 LFIANSQFVARRIKKFYGRES---TVIYPPVDTDAFAPAA--------DKEDY--------YLTASRLVPYKRIDLAVEA 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 226 LSKLKHRdfyCLMVGDisrHPNFtNRVKEliaalKLQNKIQIFGNDSDIInlygISDIIVSAS--IEP--EAFGRTIIEG 301
Cdd:cd03804 221 FNELPKR---LVVIGD---GPDL-DRLRA-----MASPNVEFLGYQPDEV----LKELLSKARafVFAaeEDFGIVPVEA 284
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1962964333 302 QAMEKLVIATNIGGAVETINNNITGFHVEPNNAEALAEKIDYC 344
Cdd:cd03804 285 QACGTPVIAFGKGGALETVRPGPTGILFGEQTVESLKAAVEEF 327
|
|
| sucrsPsyn_pln |
TIGR02468 |
sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this ... |
255-339 |
1.09e-03 |
|
sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this family are sucrose-phosphate synthases of plants. This enzyme is known to exist in multigene families in several species of both monocots and dicots. The N-terminal domain is the glucosyltransferase domain. Members of this family also have a variable linker region and a C-terminal domain that resembles sucrose phosphate phosphatase (SPP) (EC 3.1.3.24) (see TIGR01485), the next and final enzyme of sucrose biosynthesis. The SPP-like domain likely serves a binding and not a catalytic function, as the reported SPP is always encoded by a distinct protein.
Pssm-ID: 274147 [Multi-domain] Cd Length: 1050 Bit Score: 41.30 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 255 LIAALKLQNKIQIFG--------NDSDIINLYGISD-----IIVSASIEPeaFGRTIIEGQAMEKLVIATNIGGAVETIN 321
Cdd:TIGR02468 534 LTSVLKLIDKYDLYGqvaypkhhKQSDVPDIYRLAAktkgvFINPAFIEP--FGLTLIEAAAHGLPMVATKNGGPVDIHR 611
|
90 100
....*....|....*....|
gi 1962964333 322 --NNitGFHVEPNNAEALAE 339
Cdd:TIGR02468 612 vlDN--GLLVDPHDQQAIAD 629
|
|
| Glyco_trans_4_2 |
pfam13477 |
Glycosyl transferase 4-like; |
31-152 |
2.27e-03 |
|
Glycosyl transferase 4-like;
Pssm-ID: 433241 [Multi-domain] Cd Length: 139 Bit Score: 38.07 E-value: 2.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 31 TIEVAKYLKILGHTPIIISAGGTLVKELDKEDILHIEMNSSSKNPFVILnNAKLIAEIIKKYNVDIVHTRSRAPAW--SS 108
Cdd:pfam13477 13 TLRWADALADRGYDVHVISSKGPAKDELIAEGIHVHRLKVPRKGPLGYL-KAFRLKKLIKKIKPDVVHVHYAKPYGllAG 91
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1962964333 109 YLATKWTNAKFLTTFHG--VYNIPN--SFKKYYNSIMLKGEKVIAVSN 152
Cdd:pfam13477 92 LAARLSGFPPVVLSAWGldVYKFPNksRLKKLLLKLNLKKATLIISTS 139
|
|
| PRK05749 |
PRK05749 |
3-deoxy-D-manno-octulosonic-acid transferase; Reviewed |
220-367 |
2.41e-03 |
|
3-deoxy-D-manno-octulosonic-acid transferase; Reviewed
Pssm-ID: 235589 [Multi-domain] Cd Length: 425 Bit Score: 39.82 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 220 LVLvEALSKLK--HRDFYCLMVgdiSRHPNftnRVKELIAALKLQN-------KIQIFGNDSDII---------NLYGIS 281
Cdd:PRK05749 248 LVL-DAHRALLkqFPNLLLILV---PRHPE---RFKEVEELLKKAGlsyvrrsQGEPPSADTDVLlgdtmgelgLLYAIA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1962964333 282 DI-IVSAS---------IEPEAFGRTIIEG-------QAMEKLViatNIGGAVETinnnitgfhvepNNAEALAEKIDYC 344
Cdd:PRK05749 321 DIaFVGGSlvkrgghnpLEPAAFGVPVISGphtfnfkEIFERLL---QAGAAIQV------------EDAEDLAKAVTYL 385
|
170 180
....*....|....*....|...
gi 1962964333 345 FSilGTDTAKKIQEAARHTVINN 367
Cdd:PRK05749 386 LT--DPDARQAYGEAGVAFLKQN 406
|
|
| |
