NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2024418348|ref|XP_421595|]
View 

cadherin-23 isoform X1 [Gallus gallus]

Protein Classification

cadherin repeat domain-containing protein( domain architecture ID 10182011)

cadherin repeat domain-containing protein similar to cadherins, which are calcium-dependent cell adhesion proteins that preferentially interact with themselves in connecting cells

CATH:  2.60.40.60
Gene Ontology:  GO:0007156|GO:0005509
PubMed:  28268172

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1576-1673 2.55e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.55e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1576 YNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRpSPPDRERQSSYCLLVTVEDEGTP 1655
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTA-KPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 1656 SLSATTKVFVTILDENDN 1673
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1469-1566 3.62e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.96  E-value: 3.62e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1469 VSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIrttNDTYGEVLVARPLDRELLDHYTLRIQASDGGVP 1548
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI---DPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 1549 PRRKEHTLRVTVLDVNDN 1566
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2116-2212 8.34e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.18  E-value: 8.34e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2116 SITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDR-FLIDATTGVIRVANlSIDREERDAYQLTVVAVDQGT 2194
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAK-PLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*...
gi 2024418348 2195 PALSGTATVSIFIDDVND 2212
Cdd:cd11304     80 PPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 937-1033 3.83e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 116.26  E-value: 3.83e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  937 PFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTP 1016
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*..
gi 2024418348 1017 SKSSTSTLTVKVLDVND 1033
Cdd:cd11304     81 PLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1149-1246 9.45e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 9.45e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1149 SYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLmRGVRPLDREQNSSHVLEVEAYNTEH 1228
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEI-TTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*...
gi 2024418348 1229 GPMRSSVRVIVYVEDVND 1246
Cdd:cd11304     80 PPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2556-2650 3.00e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 3.00e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2556 QFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSI-EGPGAEAFKINKDSGLITSRRRLQ--SYERFNLTVVATDKGRP 2632
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDreEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 2633 PLWGTTMLHIEVIDINDN 2650
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 508-600 4.60e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.18  E-value: 4.60e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  508 YNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDR--FSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGE- 584
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPp 81

                           90
                   ....*....|....*..
gi 2024418348  585 -ETAGRIRINVLDVNDN 600
Cdd:cd11304     82 lSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1042-1141 5.76e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 112.79  E-value: 5.76e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1042 IYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGpt 1121
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG-- 78

                           90       100
                   ....*....|....*....|
gi 2024418348 1122 GNRRTGTATVYVTVLDVNDN 1141
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2449-2547 2.00e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 111.25  E-value: 2.00e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2449 SYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSL--GDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNpgd 2526
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG--- 77

                           90       100
                   ....*....|....*....|.
gi 2024418348 2527 iSSNRRENSVQVLITVLDIND 2547
Cdd:cd11304     78 -GGPPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1682-1783 3.51e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 107.78  E-value: 3.51e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1682 YEVTLDEGpATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEiSHGRYTLVVTATDQcp 1761
Cdd:cd11304      2 YEVSVPEN-APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDRE-EQSSYTLTVTATDG-- 77

                           90       100
                   ....*....|....*....|..
gi 2024418348 1762 iASRRLTSTTTVLVNLNDINDN 1783
Cdd:cd11304     78 -GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1795-1890 4.10e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 107.40  E-value: 4.10e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1795 FDVTEGQP-GPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKdaELDRENIPFYNLTISARDRGVPP 1873
Cdd:cd11304      4 VSVPENAPpGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 2024418348 1874 LSSTMLVGVRVLDINDN 1890
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 181-276 4.18e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 104.70  E-value: 4.18e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  181 PYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSF--QPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKN 258
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348  259 kPLSTLANLAITITDVQD 276
Cdd:cd11304     81 -PLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1898-1998 1.05e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 103.55  E-value: 1.05e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1898 PMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPEN 1977
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90       100
                   ....*....|....*....|.
gi 2024418348 1978 IRNARRdfdLLVISIADENDN 1998
Cdd:cd11304     81 PLSSTA---TVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1360-1457 1.98e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.08  E-value: 1.98e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1360 SYEAVIMENIPLGSEVLRVQARSID--NLNQITYKFDPNTNAqalSLFKINGITGVITVKGQVDREKGDFYTLTVVA-DD 1436
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDsgENGEVTYSIVSGNED---GLFSIDPSTGEITTAKPLDREEQSSYTLTVTAtDG 77

                           90       100
                   ....*....|....*....|.
gi 2024418348 1437 GGPKVDSTVKVTITVLDENDN 1457
Cdd:cd11304     78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 609-710 1.21e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.77  E-value: 1.21e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  609 YLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFrEYFDItvSEGYGVISVNHPLDYEQvvNGVIYLTVMAKD 688
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNED-GLFSI--DPSTGEITTAKPLDREE--QSSYTLTVTATD 76

                           90       100
                   ....*....|....*....|..
gi 2024418348  689 AGNPPLNSTVPVTIEVFDENDN 710
Cdd:cd11304     77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 718-817 5.66e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.84  E-value: 5.66e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  718 SYVIAVMEDIMAGATVLFLNATDLDrSREYGQesIIYSLEG---SSHFRINARSGEITTTSLLDREAKSEYILIVRAVDG 794
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGE--VTYSIVSgneDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|...
gi 2024418348  795 GVghHQKTGIAMVNITLLDINDN 817
Cdd:cd11304     78 GG--PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 285-389 7.73e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 7.73e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  285 PYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPfysSGFILTVKGTel 364
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ---SSYTLTVTAT-- 75

                           90       100
                   ....*....|....*....|....*
gi 2024418348  365 ndDRTPSNATVTTTFNILVIDVNDN 389
Cdd:cd11304     76 --DGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2344-2441 1.45e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 1.45e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2344 FTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLeDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSP 2423
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI-DPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 2424 RRSAEIPVYLQIVDINDN 2441
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2663-2761 3.59e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 3.59e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2663 LHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLktgaGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQ 2742
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 2024418348 2743 PAYETMQPLQVALDDIDDN 2761
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1261-1351 3.66e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 3.66e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1261 LRETAGIGTSVAVVRATDRDTGNGGLVSYQILSG-AEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGF 1339
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|..
gi 2024418348 1340 CSVYVSLLNELD 1351
Cdd:cd11304     86 ATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2006-2108 9.42e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 89.29  E-value: 9.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2006 SYQAEVMENSPAGTPVTMLNgpilALDSDQGSNAVVTYQLL-GTSPDLFIINNRTGVVSVKpgGVIDREALldPLLEFTL 2084
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVS----ATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTA--KPLDREEQ--SSYTLTV 72

                           90       100
                   ....*....|....*....|....*.
gi 2024418348 2085 IALDTGG--LNSTASLTVTILDDNDN 2108
Cdd:cd11304     73 TATDGGGppLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 825-929 1.07e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 89.29  E-value: 1.07e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  825 PYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPN--KFYSLNSTSGKIRTSGvQLDRENPNpqeaelMRRIVVS 902
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNedGLFSIDPSTGEITTAK-PLDREEQS------SYTLTVT 73

                           90       100
                   ....*....|....*....|....*..
gi 2024418348  903 VTDCGRPPLraTSSATVFVNLLDLNDN 929
Cdd:cd11304     74 ATDGGGPPL--SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 87-173 4.93e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 84.67  E-value: 4.93e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   87 INEDTPVGSSVTQLLARDLD---NDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIK--- 160
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDsgeNGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLsst 85

                           90
                   ....*....|...
gi 2024418348  161 GTVNIQVGDVNDN 173
Cdd:cd11304     86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2223-2332 7.94e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 7.94e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2223 TVSVPESATPGTVVAEVTAIDRDLHP--RLEYYLLEivarddtdalvSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVT 2300
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVS-----------GNEDGLFSIDPSTGEITTAKPLDREEQSSYTLT 71

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2024418348 2301 ISVHDNASEVtdRSVSvpnAKLTVNVLDVNDN 2332
Cdd:cd11304     72 VTATDGGGPP--LSST---ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2778-2888 4.85e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 81.59  E-value: 4.85e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2778 LSVPEHSQPGTVVGNVTgAVDADEGSNAIVYYFIAAGNRESNFQLSRE-GKLQVLRDLDREKEPYYSIIVKASSQRnwSP 2856
Cdd:cd11304      4 VSVPENAPPGTVVLTVS-ATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDGG--GP 80

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2024418348 2857 PRSQRAgraqhwdlstdltlqEVRIFLDDIND 2888
Cdd:cd11304     81 PLSSTA---------------TVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 397-499 8.09e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 69.65  E-value: 8.09e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  397 EYSVAIPELAQVGFALpLFIQVQDKDEGPNSVFEVYLV-GNNSNHFIISPTSiqGkadiRVRVAVPLDFETIPRYEFSLF 475
Cdd:cd11304      1 SYEVSVPENAPPGTVV-LTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPST--G----EITTAKPLDREEQSSYTLTVT 73

                           90       100
                   ....*....|....*....|....*
gi 2024418348  476 ANES-IPEHVGFARVKISLINENDN 499
Cdd:cd11304     74 ATDGgGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2897-2998 9.05e-08

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 52.32  E-value: 9.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2897 EYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILgiryikqhsndSEEVANIFSIGTLDGILRTFDLFTAYNPGYFV 2976
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-----------SGNEDGLFSIDPSTGEITTAKPLDREEQSSYT 69

                           90       100
                   ....*....|....*....|....
gi 2024418348 2977 VDIMASDLVG--HNDTAIVGIYIL 2998
Cdd:cd11304     70 LTVTATDGGGppLSSTATVTITVL 93
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1576-1673 2.55e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.55e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1576 YNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRpSPPDRERQSSYCLLVTVEDEGTP 1655
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTA-KPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 1656 SLSATTKVFVTILDENDN 1673
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1469-1566 3.62e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.96  E-value: 3.62e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1469 VSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIrttNDTYGEVLVARPLDRELLDHYTLRIQASDGGVP 1548
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI---DPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 1549 PRRKEHTLRVTVLDVNDN 1566
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2116-2212 8.34e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.18  E-value: 8.34e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2116 SITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDR-FLIDATTGVIRVANlSIDREERDAYQLTVVAVDQGT 2194
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAK-PLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*...
gi 2024418348 2195 PALSGTATVSIFIDDVND 2212
Cdd:cd11304     80 PPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 937-1033 3.83e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 116.26  E-value: 3.83e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  937 PFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTP 1016
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*..
gi 2024418348 1017 SKSSTSTLTVKVLDVND 1033
Cdd:cd11304     81 PLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1149-1246 9.45e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 9.45e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1149 SYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLmRGVRPLDREQNSSHVLEVEAYNTEH 1228
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEI-TTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*...
gi 2024418348 1229 GPMRSSVRVIVYVEDVND 1246
Cdd:cd11304     80 PPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2556-2650 3.00e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 3.00e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2556 QFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSI-EGPGAEAFKINKDSGLITSRRRLQ--SYERFNLTVVATDKGRP 2632
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDreEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 2633 PLWGTTMLHIEVIDINDN 2650
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 508-600 4.60e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.18  E-value: 4.60e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  508 YNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDR--FSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGE- 584
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPp 81

                           90
                   ....*....|....*..
gi 2024418348  585 -ETAGRIRINVLDVNDN 600
Cdd:cd11304     82 lSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1042-1141 5.76e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 112.79  E-value: 5.76e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1042 IYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGpt 1121
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG-- 78

                           90       100
                   ....*....|....*....|
gi 2024418348 1122 GNRRTGTATVYVTVLDVNDN 1141
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2449-2547 2.00e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 111.25  E-value: 2.00e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2449 SYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSL--GDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNpgd 2526
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG--- 77

                           90       100
                   ....*....|....*....|.
gi 2024418348 2527 iSSNRRENSVQVLITVLDIND 2547
Cdd:cd11304     78 -GGPPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1682-1783 3.51e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 107.78  E-value: 3.51e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1682 YEVTLDEGpATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEiSHGRYTLVVTATDQcp 1761
Cdd:cd11304      2 YEVSVPEN-APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDRE-EQSSYTLTVTATDG-- 77

                           90       100
                   ....*....|....*....|..
gi 2024418348 1762 iASRRLTSTTTVLVNLNDINDN 1783
Cdd:cd11304     78 -GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1795-1890 4.10e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 107.40  E-value: 4.10e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1795 FDVTEGQP-GPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKdaELDRENIPFYNLTISARDRGVPP 1873
Cdd:cd11304      4 VSVPENAPpGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 2024418348 1874 LSSTMLVGVRVLDINDN 1890
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 181-276 4.18e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 104.70  E-value: 4.18e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  181 PYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSF--QPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKN 258
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348  259 kPLSTLANLAITITDVQD 276
Cdd:cd11304     81 -PLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1898-1998 1.05e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 103.55  E-value: 1.05e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1898 PMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPEN 1977
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90       100
                   ....*....|....*....|.
gi 2024418348 1978 IRNARRdfdLLVISIADENDN 1998
Cdd:cd11304     81 PLSSTA---TVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1486-1568 1.55e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 99.73  E-value: 1.55e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1486 ARDPDAGSNGQVTFSLTAGNVGQAFEIrttNDTYGEVLVARPLDRELLDHYTLRIQASDGGVPPRRKEHTLRVTVLDVND 1565
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSI---DPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 2024418348  1566 NPP 1568
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1360-1457 1.98e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.08  E-value: 1.98e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1360 SYEAVIMENIPLGSEVLRVQARSID--NLNQITYKFDPNTNAqalSLFKINGITGVITVKGQVDREKGDFYTLTVVA-DD 1436
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDsgENGEVTYSIVSGNED---GLFSIDPSTGEITTAKPLDREEQSSYTLTVTAtDG 77

                           90       100
                   ....*....|....*....|.
gi 2024418348 1437 GGPKVDSTVKVTITVLDENDN 1457
Cdd:cd11304     78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 609-710 1.21e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.77  E-value: 1.21e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  609 YLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFrEYFDItvSEGYGVISVNHPLDYEQvvNGVIYLTVMAKD 688
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNED-GLFSI--DPSTGEITTAKPLDREE--QSSYTLTVTATD 76

                           90       100
                   ....*....|....*....|..
gi 2024418348  689 AGNPPLNSTVPVTIEVFDENDN 710
Cdd:cd11304     77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 718-817 5.66e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.84  E-value: 5.66e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  718 SYVIAVMEDIMAGATVLFLNATDLDrSREYGQesIIYSLEG---SSHFRINARSGEITTTSLLDREAKSEYILIVRAVDG 794
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGE--VTYSIVSgneDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|...
gi 2024418348  795 GVghHQKTGIAMVNITLLDINDN 817
Cdd:cd11304     78 GG--PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 285-389 7.73e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 7.73e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  285 PYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPfysSGFILTVKGTel 364
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ---SSYTLTVTAT-- 75

                           90       100
                   ....*....|....*....|....*
gi 2024418348  365 ndDRTPSNATVTTTFNILVIDVNDN 389
Cdd:cd11304     76 --DGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1811-1892 1.22e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 94.34  E-value: 1.22e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1811 AHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKdaELDRENIPFYNLTISARDRGVPPLSSTMLVGVRVLDINDN 1890
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  1891 DP 1892
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2344-2441 1.45e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 1.45e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2344 FTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLeDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSP 2423
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI-DPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 2424 RRSAEIPVYLQIVDINDN 2441
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2557-2645 2.42e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 93.90  E-value: 2.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2557 FSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSI-EGPGAEAFKINKDSGLITSRRRLQ--SYERFNLTVVATDKGRPP 2633
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlGGGPGGNFRIDPDTGDISTTKPLDreSIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024418348 2634 LWGTTMLHIEVI 2645
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2663-2761 3.59e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 3.59e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2663 LHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLktgaGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQ 2742
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 2024418348 2743 PAYETMQPLQVALDDIDDN 2761
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 957-1036 3.64e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 92.80  E-value: 3.64e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   957 AIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPSKSSTSTLTVKVLDVNDESP 1036
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1261-1351 3.66e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 3.66e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1261 LRETAGIGTSVAVVRATDRDTGNGGLVSYQILSG-AEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGF 1339
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|..
gi 2024418348 1340 CSVYVSLLNELD 1351
Cdd:cd11304     86 ATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
2117-2207 4.78e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 92.75  E-value: 4.78e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2117 ITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDR-FLIDATTGVIRVANlSIDREERDAYQLTVVAVDQGTP 2195
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGnFRIDPDTGDISTTK-PLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 2024418348 2196 ALSGTATVSIFI 2207
Cdd:pfam00028   80 PLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2135-2215 8.40e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 91.64  E-value: 8.40e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2135 TATDADSGLNKQLDYRIEGGGQDR-FLIDATTGVIRVANlSIDREERDAYQLTVVAVDQGTPALSGTATVSIFIDDVNDC 2213
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGlFSIDPETGEITTTK-PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  2214 RP 2215
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1063-1143 1.61e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 90.87  E-value: 1.61e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1063 TDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGptGNRRTGTATVYVTVLDVNDNR 1142
Cdd:smart00112    3 TDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG--GPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024418348  1143 P 1143
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
938-1029 2.57e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 90.82  E-value: 2.57e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  938 FIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPS 1017
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024418348 1018 KSSTSTLTVKVL 1029
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1469-1561 5.13e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 90.05  E-value: 5.13e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1469 VSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIRTTNdtyGEVLVARPLDRELLDHYTLRIQASDGGVP 1548
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDT---GDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1549 PRRKEHTLRVTVL 1561
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2575-2652 5.71e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.33  E-value: 5.71e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2575 TATDLDEGDNGVVTYSI-EGPGAEAFKINKDSGLITSRRRL--QSYERFNLTVVATDKGRPPLWGTTMLHIEVIDINDNR 2651
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLdrEEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024418348  2652 P 2652
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1701-1785 5.77e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.33  E-value: 5.77e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1701 QALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEiSHGRYTLVVTATDQcpiASRRLTSTTTVLVNLNDI 1780
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDRE-EQPEYTLTVEATDG---GGPPLSSTATVTITVLDV 76


                    ....*
gi 2024418348  1781 NDNCP 1785
Cdd:smart00112   77 NDNAP 81
Cadherin pfam00028
Cadherin domain;
1150-1242 6.29e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 89.67  E-value: 6.29e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1150 YEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLmRGVRPLDREQNSSHVLEVEAYNTEHG 1229
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDI-STTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1230 PMRSSVRVIVYVE 1242
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2006-2108 9.42e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 89.29  E-value: 9.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2006 SYQAEVMENSPAGTPVTMLNgpilALDSDQGSNAVVTYQLL-GTSPDLFIINNRTGVVSVKpgGVIDREALldPLLEFTL 2084
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVS----ATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTA--KPLDREEQ--SSYTLTV 72

                           90       100
                   ....*....|....*....|....*.
gi 2024418348 2085 IALDTGG--LNSTASLTVTILDDNDN 2108
Cdd:cd11304     73 TATDGGGppLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1594-1675 1.05e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.56  E-value: 1.05e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1594 RATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRpSPPDRERQSSYCLLVTVEDEGTPSLSATTKVFVTILDENDN 1673
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTT-KPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  1674 AP 1675
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 825-929 1.07e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 89.29  E-value: 1.07e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  825 PYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPN--KFYSLNSTSGKIRTSGvQLDRENPNpqeaelMRRIVVS 902
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNedGLFSIDPSTGEITTAK-PLDREEQS------SYTLTVT 73

                           90       100
                   ....*....|....*....|....*..
gi 2024418348  903 VTDCGRPPLraTSSATVFVNLLDLNDN 929
Cdd:cd11304     74 ATDGGGPPL--SSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1043-1136 2.68e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 87.74  E-value: 2.68e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1043 YNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGPTG 1122
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|....
gi 2024418348 1123 nrRTGTATVYVTVL 1136
Cdd:pfam00028   81 --LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
508-595 5.56e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 86.97  E-value: 5.56e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  508 YNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDP--DRFSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGE- 584
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpgGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPp 80

                           90
                   ....*....|..
gi 2024418348  585 -ETAGRIRINVL 595
Cdd:pfam00028   81 lSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1576-1668 6.01e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 86.97  E-value: 6.01e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1576 YNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRpSPPDRERQSSYCLLVTVEDEGTP 1655
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTT-KPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1656 SLSATTKVFVTIL 1668
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1794-1885 1.28e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 85.82  E-value: 1.28e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1794 PFDVTEGQP-GPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKdaELDRENIPFYNLTISARDRGVP 1872
Cdd:pfam00028    2 SASVPENAPvGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK--PLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1873 PLSSTMLVGVRVL 1885
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1168-1249 1.83e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 85.09  E-value: 1.83e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1168 KATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLmRGVRPLDREQNSSHVLEVEAYNTEHGPMRSSVRVIVYVEDVNDE 1247
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEI-TTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  1248 VP 1249
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 87-173 4.93e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 84.67  E-value: 4.93e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   87 INEDTPVGSSVTQLLARDLD---NDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIK--- 160
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDsgeNGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLsst 85

                           90
                   ....*....|...
gi 2024418348  161 GTVNIQVGDVNDN 173
Cdd:cd11304     86 ATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2680-2763 5.03e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 83.94  E-value: 5.03e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2680 ATDKDEGLNGAVLYSLLktgaGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQPAYETMQPLQVALDDID 2759
Cdd:smart00112    2 ATDADSGENGKVTYSIL----SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 2024418348  2760 DNEP 2763
Cdd:smart00112   78 DNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2468-2550 5.60e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 83.94  E-value: 5.60e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2468 KATDADSGRFAVIQYSL--GDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNpgdiSSNRRENSVQVLITVLDI 2545
Cdd:smart00112    1 SATDADSGENGKVTYSIlsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG----GGPPLSSTATVTITVLDV 76


                    ....*
gi 2024418348  2546 NDFRP 2550
Cdd:smart00112   77 NDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2223-2332 7.94e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 7.94e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2223 TVSVPESATPGTVVAEVTAIDRDLHP--RLEYYLLEivarddtdalvSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVT 2300
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVS-----------GNEDGLFSIDPSTGEITTAKPLDREEQSSYTLT 71

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2024418348 2301 ISVHDNASEVtdRSVSvpnAKLTVNVLDVNDN 2332
Cdd:cd11304     72 VTATDGGGPP--LSST---ATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
182-272 1.60e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.73  E-value: 1.60e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  182 YSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSF--QPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKnK 259
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlgGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-P 79

                           90
                   ....*....|...
gi 2024418348  260 PLSTLANLAITIT 272
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 526-602 1.63e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 82.40  E-value: 1.63e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   526 HATDNDVGSYGKVSYFFSDDPDR--FSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGE--ETAGRIRINVLDVNDNV 601
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplSSTATVTITVLDVNDNA 80


                    .
gi 2024418348   602 P 602
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1682-1777 1.69e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.73  E-value: 1.69e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1682 YEVTLDEGpATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEiSHGRYTLVVTATDQcp 1761
Cdd:pfam00028    1 YSASVPEN-APVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRE-SIGEYELTVEATDS-- 76

                           90
                   ....*....|....*.
gi 2024418348 1762 iASRRLTSTTTVLVNL 1777
Cdd:pfam00028   77 -GGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1918-2000 4.24e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 81.24  E-value: 4.24e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1918 AQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPENIRNARRdfdLLVISIADEND 1997
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTA---TVTITVLDVND 78


                    ...
gi 2024418348  1998 NHP 2000
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2778-2888 4.85e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 81.59  E-value: 4.85e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2778 LSVPEHSQPGTVVGNVTgAVDADEGSNAIVYYFIAAGNRESNFQLSRE-GKLQVLRDLDREKEPYYSIIVKASSQRnwSP 2856
Cdd:cd11304      4 VSVPENAPPGTVVLTVS-ATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDGG--GP 80

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2024418348 2857 PRSQRAgraqhwdlstdltlqEVRIFLDDIND 2888
Cdd:cd11304     81 PLSSTA---------------TVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
2456-2543 5.39e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 81.19  E-value: 5.39e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2456 EDVPLGTVILRVKATDADSGRFAVIQYSL--GDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNpgdiSSNRRE 2533
Cdd:pfam00028    7 ENAPVGTEVLTVTATDPDLGPNGRIFYSIlgGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDS----GGPPLS 82

                           90
                   ....*....|
gi 2024418348 2534 NSVQVLITVL 2543
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 627-712 1.63e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 79.70  E-value: 1.63e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   627 RASDEDSPPNNQITYSIVHASAFrEYFDITvsEGYGVISVNHPLDYEQvvNGVIYLTVMAKDAGNPPLNSTVPVTIEVFD 706
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDD-GLFSID--PETGEITTTKPLDREE--QPEYTLTVEATDGGGPPLSSTATVTITVLD 75


                    ....*.
gi 2024418348   707 ENDNPP 712
Cdd:smart00112   76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
1900-1974 3.23e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 79.27  E-value: 3.23e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024418348 1900 NITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDN 1974
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDS 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2362-2443 5.77e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.16  E-value: 5.77e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2362 SAVDPDKGANGQITYELLDLSPEGYACLEDQSaGKVVANRTVDYEEVQWLNFTVRASDNGSPRRSAEIPVYLQIVDINDN 2441
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPET-GEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  2442 NP 2443
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1261-1347 1.04e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 1.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1261 LRETAGIGTSVAVVRATDRDTGNGGLVSYQILSG-AEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGF 1339
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 2024418348 1340 CSVYVSLL 1347
Cdd:pfam00028   85 ATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 737-819 1.07e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 77.39  E-value: 1.07e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   737 NATDLDrSREYGQesIIYSLEGSS---HFRINARSGEITTTSLLDREAKSEYILIVRAVDGGVghHQKTGIAMVNITLLD 813
Cdd:smart00112    1 SATDAD-SGENGK--VTYSILSGNddgLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGG--PPLSSTATVTITVLD 75


                    ....*.
gi 2024418348   814 INDNYP 819
Cdd:smart00112   76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
2664-2753 1.56e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.34  E-value: 1.56e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2664 HIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLKTGAGNKdweyFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQP 2743
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGN----FRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|
gi 2024418348 2744 AYETMQPLQV 2753
Cdd:pfam00028   80 PLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1388-1459 9.10e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 74.69  E-value: 9.10e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024418348  1388 QITYKFDPNTNAqalSLFKINGITGVITVKGQVDREKGDFYTLTVVA-DDGGPKVDSTVKVTITVLDENDNSP 1459
Cdd:smart00112   12 KVTYSILSGNDD---GLFSIDPETGEITTTKPLDREEQPEYTLTVEAtDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1275-1353 1.53e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.53e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1275 RATDRDTGNGGLVSYQILSG-AEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGFCSVYVSLLNELDEA 1353
Cdd:smart00112    1 SATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80
Cadherin pfam00028
Cadherin domain;
609-704 1.87e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 74.26  E-value: 1.87e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  609 YLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFReYFDITVSEgyGVISVNHPLDYEQvvNGVIYLTVMAKD 688
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGG-NFRIDPDT--GDISTTKPLDRES--IGEYELTVEATD 75

                           90
                   ....*....|....*.
gi 2024418348  689 AGNPPLNSTVPVTIEV 704
Cdd:pfam00028   76 SGGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 200-279 2.27e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.54  E-value: 2.27e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   200 NATDPDQGAGGSVLYSF--QPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDkNKPLSTLANLAITITDVQDM 277
Cdd:smart00112    1 SATDADSGENGKVTYSIlsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG-GPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348   278 DP 279
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
719-812 5.91e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.72  E-value: 5.91e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  719 YVIAVMEDIMAGATVLFLNATDLDrsrEYGQESIIYSL---EGSSHFRINARSGEITTTSLLDREAKSEYILIVRAVDGG 795
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPD---LGPNGRIFYSIlggGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*..
gi 2024418348  796 VghHQKTGIAMVNITLL 812
Cdd:pfam00028   78 G--PPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1361-1452 7.18e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.33  E-value: 7.18e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1361 YEAVIMENIPLGSEVLRVQARSID-NLN-QITYKFDPNTNAQalsLFKINGITGVITVKGQVDREKGDFYTLTVVA-DDG 1437
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDlGPNgRIFYSILGGGPGG---NFRIDPDTGDISTTKPLDRESIGEYELTVEAtDSG 77

                           90
                   ....*....|....*
gi 2024418348 1438 GPKVDSTVKVTITVL 1452
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 304-391 2.00e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 70.84  E-value: 2.00e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   304 TAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENpfySSGFILTVKGTelndDRTPSNATVTTTFNILV 383
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREE---QPEYTLTVEAT----DGGGPPLSSTATVTITV 73


                    ....*...
gi 2024418348   384 IDVNDNAP 391
Cdd:smart00112   74 LDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 397-499 8.09e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 69.65  E-value: 8.09e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  397 EYSVAIPELAQVGFALpLFIQVQDKDEGPNSVFEVYLV-GNNSNHFIISPTSiqGkadiRVRVAVPLDFETIPRYEFSLF 475
Cdd:cd11304      1 SYEVSVPENAPPGTVV-LTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPST--G----EITTAKPLDREEQSSYTLTVT 73

                           90       100
                   ....*....|....*....|....*
gi 2024418348  476 ANES-IPEHVGFARVKISLINENDN 499
Cdd:cd11304     74 ATDGgGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2779-2862 1.97e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.97e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2779 SVPEHSQPGTVVGNVTgAVDADEGSNAIVYYFIAAGNRESNFQLSRE-GKLQVLRDLDREKEPYYSIIVKASSqrNWSPP 2857
Cdd:pfam00028    4 SVPENAPVGTEVLTVT-ATDPDLGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATD--SGGPP 80


                   ....*
gi 2024418348 2858 RSQRA 2862
Cdd:pfam00028   81 LSSTA 85
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2030-2110 2.24e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.76  E-value: 2.24e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2030 ALDSDQGSNAVVTYQLL-GTSPDLFIINNRTGVVSVKpgGVIDREALldPLLEFTLIALDTGG--LNSTASLTVTILDDN 2106
Cdd:smart00112    2 ATDADSGENGKVTYSILsGNDDGLFSIDPETGEITTT--KPLDREEQ--PEYTLTVEATDGGGppLSSTATVTITVLDVN 77


                    ....
gi 2024418348  2107 DNRP 2110
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
2344-2435 1.00e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 66.17  E-value: 1.00e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2344 FTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLeDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSP 2423
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRI-DPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 2024418348 2424 RRSAEIPVYLQI 2435
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
2007-2103 1.93e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 1.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2007 YQAEVMENSPAGTPVtmlnGPILALDSDQGSNAVVTYQLLGTSPD-LFIINNRTGVVSVKpgGVIDREALldPLLEFTLI 2085
Cdd:pfam00028    1 YSASVPENAPVGTEV----LTVTATDPDLGPNGRIFYSILGGGPGgNFRIDPDTGDISTT--KPLDRESI--GEYELTVE 72

                           90       100
                   ....*....|....*....|
gi 2024418348 2086 ALDTG--GLNSTASLTVTIL 2103
Cdd:pfam00028   73 ATDSGgpPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 102-175 2.33e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.06  E-value: 2.33e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   102 ARDLD---NDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIK---GTVNIQVGDVNDNAP 175
Cdd:smart00112    2 ATDADsgeNGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLsstATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 844-931 3.12e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 64.68  E-value: 3.12e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   844 VAVDPDLGENGTVVYSIRPPN--KFYSLNSTSGKIRTSGvQLDRENPNpqeaelMRRIVVSVTDCGRPPLRATssATVFV 921
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEITTTK-PLDREEQP------EYTLTVEATDGGGPPLSST--ATVTI 71

                            90
                    ....*....|
gi 2024418348   922 NLLDLNDNDP 931
Cdd:smart00112   72 TVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
286-382 4.41e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.63  E-value: 4.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  286 YSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPfysSGFILTVKGTelN 365
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESI---GEYELTVEAT--D 75

                           90
                   ....*....|....*..
gi 2024418348  366 DDRTPSNATVTTTFNIL 382
Cdd:pfam00028   76 SGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
826-921 2.86e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 62.32  E-value: 2.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  826 YFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIR--PPNKFYSLNSTSGKIRTsGVQLDRENPNpqeaelMRRIVVSV 903
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDPDTGDIST-TKPLDRESIG------EYELTVEA 73

                           90
                   ....*....|....*...
gi 2024418348  904 TDCGRPPLRATSSATVFV 921
Cdd:pfam00028   74 TDSGGPPLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
87-167 4.80e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.55  E-value: 4.80e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   87 INEDTPVGSSVTQLLARDLDNDP---LVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIK--- 160
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLsst 84


                   ....*..
gi 2024418348  161 GTVNIQV 167
Cdd:pfam00028   85 ATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2796-2891 2.52e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.29  E-value: 2.52e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2796 AVDADEGSNAIVYYFIAAGNRESNFQLSRE-GKLQVLRDLDREKEPYYSIIVKASSQRnwSPPRSqragraqhwdlstdl 2874
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGG--GPPLS--------------- 64

                            90
                    ....*....|....*..
gi 2024418348  2875 TLQEVRIFLDDINDQSP 2891
Cdd:smart00112   65 STATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 417-501 6.97e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 57.74  E-value: 6.97e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   417 QVQDKDEGPNSVFEVYLV-GNNSNHFIISPTSIQgkadirVRVAVPLDFETIPRYEFSLFA-NESIPEHVGFARVKISLI 494
Cdd:smart00112    1 SATDADSGENGKVTYSILsGNDDGLFSIDPETGE------ITTTKPLDREEQPEYTLTVEAtDGGGPPLSSTATVTITVL 74


                    ....*..
gi 2024418348   495 NENDNRP 501
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2222-2327 9.39e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 58.08  E-value: 9.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2222 QTVSVPESATPGTVVAEVTAIDRDLHP--RLEYYLLEivarddtdalvSDQQGTFTVDFRTGAVKIKNPLNRELVATYEV 2299
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngRIFYSILG-----------GGPGGNFRIDPDTGDISTTKPLDRESIGEYEL 69

                           90       100
                   ....*....|....*....|....*...
gi 2024418348 2300 TISVHDNASEVTDRSVSVpnaklTVNVL 2327
Cdd:pfam00028   70 TVEATDSGGPPLSSTATV-----TITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2240-2334 1.05e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 54.66  E-value: 1.05e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2240 TAIDRDLHP--RLEYYLLEivarddtdalvSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVTISVHDNASevTDRSVSV 2317
Cdd:smart00112    1 SATDADSGEngKVTYSILS-----------GNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGG--PPLSSTA 67

                            90
                    ....*....|....*..
gi 2024418348  2318 PnakLTVNVLDVNDNTP 2334
Cdd:smart00112   68 T---VTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2897-2998 9.05e-08

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 52.32  E-value: 9.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2897 EYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILgiryikqhsndSEEVANIFSIGTLDGILRTFDLFTAYNPGYFV 2976
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-----------SGNEDGLFSIDPSTGEITTAKPLDREEQSSYT 69

                           90       100
                   ....*....|....*....|....
gi 2024418348 2977 VDIMASDLVG--HNDTAIVGIYIL 2998
Cdd:cd11304     70 LTVTATDGGGppLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
398-494 1.15e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 49.22  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  398 YSVAIPELAQVGfALPLFIQVQDKDEGPNSVFEVYLVGNNS-NHFIISPTSiqGkadiRVRVAVPLDFETIPRYEFSLFA 476
Cdd:pfam00028    1 YSASVPENAPVG-TEVLTVTATDPDLGPNGRIFYSILGGGPgGNFRIDPDT--G----DISTTKPLDRESIGEYELTVEA 73

                           90
                   ....*....|....*....
gi 2024418348  477 -NESIPEHVGFARVKISLI 494
Cdd:pfam00028   74 tDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2898-2998 1.17e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 43.44  E-value: 1.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2898 YTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILGiryikqhsndsEEVANIFSIGTLDGILRTFDLFTAYNPGYFVV 2977
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILG-----------GGPGGNFRIDPDTGDISTTKPLDRESIGEYEL 69

                           90       100
                   ....*....|....*....|...
gi 2024418348 2978 DIMASDLVGHN--DTAIVGIYIL 2998
Cdd:pfam00028   70 TVEATDSGGPPlsSTATVTITVL 92
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1576-1673 2.55e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 119.73  E-value: 2.55e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1576 YNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRpSPPDRERQSSYCLLVTVEDEGTP 1655
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTA-KPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 1656 SLSATTKVFVTILDENDN 1673
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1469-1566 3.62e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.96  E-value: 3.62e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1469 VSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIrttNDTYGEVLVARPLDRELLDHYTLRIQASDGGVP 1548
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI---DPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 1549 PRRKEHTLRVTVLDVNDN 1566
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2116-2212 8.34e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.18  E-value: 8.34e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2116 SITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDR-FLIDATTGVIRVANlSIDREERDAYQLTVVAVDQGT 2194
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAK-PLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*...
gi 2024418348 2195 PALSGTATVSIFIDDVND 2212
Cdd:cd11304     80 PPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 937-1033 3.83e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 116.26  E-value: 3.83e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  937 PFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTP 1016
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*..
gi 2024418348 1017 SKSSTSTLTVKVLDVND 1033
Cdd:cd11304     81 PLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1149-1246 9.45e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 9.45e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1149 SYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLmRGVRPLDREQNSSHVLEVEAYNTEH 1228
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEI-TTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*...
gi 2024418348 1229 GPMRSSVRVIVYVEDVND 1246
Cdd:cd11304     80 PPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2556-2650 3.00e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 3.00e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2556 QFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSI-EGPGAEAFKINKDSGLITSRRRLQ--SYERFNLTVVATDKGRP 2632
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvSGNEDGLFSIDPSTGEITTAKPLDreEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 2633 PLWGTTMLHIEVIDINDN 2650
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 508-600 4.60e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.18  E-value: 4.60e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  508 YNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDR--FSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGE- 584
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPp 81

                           90
                   ....*....|....*..
gi 2024418348  585 -ETAGRIRINVLDVNDN 600
Cdd:cd11304     82 lSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1042-1141 5.76e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 112.79  E-value: 5.76e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1042 IYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGpt 1121
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG-- 78

                           90       100
                   ....*....|....*....|
gi 2024418348 1122 GNRRTGTATVYVTVLDVNDN 1141
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2449-2547 2.00e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 111.25  E-value: 2.00e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2449 SYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSL--GDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNpgd 2526
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG--- 77

                           90       100
                   ....*....|....*....|.
gi 2024418348 2527 iSSNRRENSVQVLITVLDIND 2547
Cdd:cd11304     78 -GGPPLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1682-1783 3.51e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 107.78  E-value: 3.51e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1682 YEVTLDEGpATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEiSHGRYTLVVTATDQcp 1761
Cdd:cd11304      2 YEVSVPEN-APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDRE-EQSSYTLTVTATDG-- 77

                           90       100
                   ....*....|....*....|..
gi 2024418348 1762 iASRRLTSTTTVLVNLNDINDN 1783
Cdd:cd11304     78 -GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1795-1890 4.10e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 107.40  E-value: 4.10e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1795 FDVTEGQP-GPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKdaELDRENIPFYNLTISARDRGVPP 1873
Cdd:cd11304      4 VSVPENAPpGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 2024418348 1874 LSSTMLVGVRVLDINDN 1890
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 181-276 4.18e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 104.70  E-value: 4.18e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  181 PYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSF--QPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKN 258
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIvsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348  259 kPLSTLANLAITITDVQD 276
Cdd:cd11304     81 -PLSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1898-1998 1.05e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 103.55  E-value: 1.05e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1898 PMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPEN 1977
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90       100
                   ....*....|....*....|.
gi 2024418348 1978 IRNARRdfdLLVISIADENDN 1998
Cdd:cd11304     81 PLSSTA---TVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1486-1568 1.55e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 99.73  E-value: 1.55e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1486 ARDPDAGSNGQVTFSLTAGNVGQAFEIrttNDTYGEVLVARPLDRELLDHYTLRIQASDGGVPPRRKEHTLRVTVLDVND 1565
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSI---DPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 2024418348  1566 NPP 1568
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1360-1457 1.98e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 100.08  E-value: 1.98e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1360 SYEAVIMENIPLGSEVLRVQARSID--NLNQITYKFDPNTNAqalSLFKINGITGVITVKGQVDREKGDFYTLTVVA-DD 1436
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDsgENGEVTYSIVSGNED---GLFSIDPSTGEITTAKPLDREEQSSYTLTVTAtDG 77

                           90       100
                   ....*....|....*....|.
gi 2024418348 1437 GGPKVDSTVKVTITVLDENDN 1457
Cdd:cd11304     78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 609-710 1.21e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.77  E-value: 1.21e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  609 YLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFrEYFDItvSEGYGVISVNHPLDYEQvvNGVIYLTVMAKD 688
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNED-GLFSI--DPSTGEITTAKPLDREE--QSSYTLTVTATD 76

                           90       100
                   ....*....|....*....|..
gi 2024418348  689 AGNPPLNSTVPVTIEVFDENDN 710
Cdd:cd11304     77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 718-817 5.66e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.84  E-value: 5.66e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  718 SYVIAVMEDIMAGATVLFLNATDLDrSREYGQesIIYSLEG---SSHFRINARSGEITTTSLLDREAKSEYILIVRAVDG 794
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGE--VTYSIVSgneDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|...
gi 2024418348  795 GVghHQKTGIAMVNITLLDINDN 817
Cdd:cd11304     78 GG--PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 285-389 7.73e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 7.73e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  285 PYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPfysSGFILTVKGTel 364
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ---SSYTLTVTAT-- 75

                           90       100
                   ....*....|....*....|....*
gi 2024418348  365 ndDRTPSNATVTTTFNILVIDVNDN 389
Cdd:cd11304     76 --DGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1811-1892 1.22e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 94.34  E-value: 1.22e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1811 AHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKdaELDRENIPFYNLTISARDRGVPPLSSTMLVGVRVLDINDN 1890
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  1891 DP 1892
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2344-2441 1.45e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 1.45e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2344 FTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLeDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSP 2423
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI-DPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....*...
gi 2024418348 2424 RRSAEIPVYLQIVDINDN 2441
Cdd:cd11304     81 PLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2557-2645 2.42e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 93.90  E-value: 2.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2557 FSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSI-EGPGAEAFKINKDSGLITSRRRLQ--SYERFNLTVVATDKGRPP 2633
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlGGGPGGNFRIDPDTGDISTTKPLDreSIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024418348 2634 LWGTTMLHIEVI 2645
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2663-2761 3.59e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 3.59e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2663 LHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLktgaGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQ 2742
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                           90
                   ....*....|....*....
gi 2024418348 2743 PAYETMQPLQVALDDIDDN 2761
Cdd:cd11304     80 PPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 957-1036 3.64e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 92.80  E-value: 3.64e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   957 AIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPSKSSTSTLTVKVLDVNDESP 1036
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1261-1351 3.66e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 93.53  E-value: 3.66e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1261 LRETAGIGTSVAVVRATDRDTGNGGLVSYQILSG-AEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGF 1339
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGnEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                           90
                   ....*....|..
gi 2024418348 1340 CSVYVSLLNELD 1351
Cdd:cd11304     86 ATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
2117-2207 4.78e-22

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 92.75  E-value: 4.78e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2117 ITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDR-FLIDATTGVIRVANlSIDREERDAYQLTVVAVDQGTP 2195
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGnFRIDPDTGDISTTK-PLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 2024418348 2196 ALSGTATVSIFI 2207
Cdd:pfam00028   80 PLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2135-2215 8.40e-22

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 91.64  E-value: 8.40e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2135 TATDADSGLNKQLDYRIEGGGQDR-FLIDATTGVIRVANlSIDREERDAYQLTVVAVDQGTPALSGTATVSIFIDDVNDC 2213
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGlFSIDPETGEITTTK-PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  2214 RP 2215
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1063-1143 1.61e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 90.87  E-value: 1.61e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1063 TDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGptGNRRTGTATVYVTVLDVNDNR 1142
Cdd:smart00112    3 TDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG--GPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024418348  1143 P 1143
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
938-1029 2.57e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 90.82  E-value: 2.57e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  938 FIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPS 1017
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024418348 1018 KSSTSTLTVKVL 1029
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1469-1561 5.13e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 90.05  E-value: 5.13e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1469 VSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIRTTNdtyGEVLVARPLDRELLDHYTLRIQASDGGVP 1548
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDT---GDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1549 PRRKEHTLRVTVL 1561
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2575-2652 5.71e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.33  E-value: 5.71e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2575 TATDLDEGDNGVVTYSI-EGPGAEAFKINKDSGLITSRRRL--QSYERFNLTVVATDKGRPPLWGTTMLHIEVIDINDNR 2651
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLdrEEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024418348  2652 P 2652
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1701-1785 5.77e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.33  E-value: 5.77e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1701 QALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEiSHGRYTLVVTATDQcpiASRRLTSTTTVLVNLNDI 1780
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDRE-EQPEYTLTVEATDG---GGPPLSSTATVTITVLDV 76


                    ....*
gi 2024418348  1781 NDNCP 1785
Cdd:smart00112   77 NDNAP 81
Cadherin pfam00028
Cadherin domain;
1150-1242 6.29e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 89.67  E-value: 6.29e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1150 YEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLmRGVRPLDREQNSSHVLEVEAYNTEHG 1229
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDI-STTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1230 PMRSSVRVIVYVE 1242
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2006-2108 9.42e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 89.29  E-value: 9.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2006 SYQAEVMENSPAGTPVTMLNgpilALDSDQGSNAVVTYQLL-GTSPDLFIINNRTGVVSVKpgGVIDREALldPLLEFTL 2084
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVS----ATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTA--KPLDREEQ--SSYTLTV 72

                           90       100
                   ....*....|....*....|....*.
gi 2024418348 2085 IALDTGG--LNSTASLTVTILDDNDN 2108
Cdd:cd11304     73 TATDGGGppLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1594-1675 1.05e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.56  E-value: 1.05e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1594 RATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRpSPPDRERQSSYCLLVTVEDEGTPSLSATTKVFVTILDENDN 1673
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTT-KPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  1674 AP 1675
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 825-929 1.07e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 89.29  E-value: 1.07e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  825 PYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPN--KFYSLNSTSGKIRTSGvQLDRENPNpqeaelMRRIVVS 902
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNedGLFSIDPSTGEITTAK-PLDREEQS------SYTLTVT 73

                           90       100
                   ....*....|....*....|....*..
gi 2024418348  903 VTDCGRPPLraTSSATVFVNLLDLNDN 929
Cdd:cd11304     74 ATDGGGPPL--SSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1043-1136 2.68e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 87.74  E-value: 2.68e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1043 YNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGPTG 1122
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|....
gi 2024418348 1123 nrRTGTATVYVTVL 1136
Cdd:pfam00028   81 --LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
508-595 5.56e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 86.97  E-value: 5.56e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  508 YNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDP--DRFSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGE- 584
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpgGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPp 80

                           90
                   ....*....|..
gi 2024418348  585 -ETAGRIRINVL 595
Cdd:pfam00028   81 lSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1576-1668 6.01e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 86.97  E-value: 6.01e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1576 YNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRpSPPDRERQSSYCLLVTVEDEGTP 1655
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTT-KPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1656 SLSATTKVFVTIL 1668
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1794-1885 1.28e-19

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 85.82  E-value: 1.28e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1794 PFDVTEGQP-GPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKdaELDRENIPFYNLTISARDRGVP 1872
Cdd:pfam00028    2 SASVPENAPvGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK--PLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024418348 1873 PLSSTMLVGVRVL 1885
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1168-1249 1.83e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 85.09  E-value: 1.83e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1168 KATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLmRGVRPLDREQNSSHVLEVEAYNTEHGPMRSSVRVIVYVEDVNDE 1247
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEI-TTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  1248 VP 1249
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 87-173 4.93e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 84.67  E-value: 4.93e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   87 INEDTPVGSSVTQLLARDLD---NDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIK--- 160
Cdd:cd11304      6 VPENAPPGTVVLTVSATDPDsgeNGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLsst 85

                           90
                   ....*....|...
gi 2024418348  161 GTVNIQVGDVNDN 173
Cdd:cd11304     86 ATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2680-2763 5.03e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 83.94  E-value: 5.03e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2680 ATDKDEGLNGAVLYSLLktgaGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQPAYETMQPLQVALDDID 2759
Cdd:smart00112    2 ATDADSGENGKVTYSIL----SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 2024418348  2760 DNEP 2763
Cdd:smart00112   78 DNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2468-2550 5.60e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 83.94  E-value: 5.60e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2468 KATDADSGRFAVIQYSL--GDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNpgdiSSNRRENSVQVLITVLDI 2545
Cdd:smart00112    1 SATDADSGENGKVTYSIlsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG----GGPPLSSTATVTITVLDV 76


                    ....*
gi 2024418348  2546 NDFRP 2550
Cdd:smart00112   77 NDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2223-2332 7.94e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 7.94e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2223 TVSVPESATPGTVVAEVTAIDRDLHP--RLEYYLLEivarddtdalvSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVT 2300
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVS-----------GNEDGLFSIDPSTGEITTAKPLDREEQSSYTLT 71

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2024418348 2301 ISVHDNASEVtdRSVSvpnAKLTVNVLDVNDN 2332
Cdd:cd11304     72 VTATDGGGPP--LSST---ATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
182-272 1.60e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.73  E-value: 1.60e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  182 YSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSF--QPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKnK 259
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIlgGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-P 79

                           90
                   ....*....|...
gi 2024418348  260 PLSTLANLAITIT 272
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 526-602 1.63e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 82.40  E-value: 1.63e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   526 HATDNDVGSYGKVSYFFSDDPDR--FSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGE--ETAGRIRINVLDVNDNV 601
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPplSSTATVTITVLDVNDNA 80


                    .
gi 2024418348   602 P 602
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1682-1777 1.69e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.73  E-value: 1.69e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1682 YEVTLDEGpATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEiSHGRYTLVVTATDQcp 1761
Cdd:pfam00028    1 YSASVPEN-APVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRE-SIGEYELTVEATDS-- 76

                           90
                   ....*....|....*.
gi 2024418348 1762 iASRRLTSTTTVLVNL 1777
Cdd:pfam00028   77 -GGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1918-2000 4.24e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 81.24  E-value: 4.24e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1918 AQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPENIRNARRdfdLLVISIADEND 1997
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTA---TVTITVLDVND 78


                    ...
gi 2024418348  1998 NHP 2000
Cdd:smart00112   79 NAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2778-2888 4.85e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 81.59  E-value: 4.85e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2778 LSVPEHSQPGTVVGNVTgAVDADEGSNAIVYYFIAAGNRESNFQLSRE-GKLQVLRDLDREKEPYYSIIVKASSQRnwSP 2856
Cdd:cd11304      4 VSVPENAPPGTVVLTVS-ATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDGG--GP 80

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2024418348 2857 PRSQRAgraqhwdlstdltlqEVRIFLDDIND 2888
Cdd:cd11304     81 PLSSTA---------------TVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
2456-2543 5.39e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 81.19  E-value: 5.39e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2456 EDVPLGTVILRVKATDADSGRFAVIQYSL--GDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNpgdiSSNRRE 2533
Cdd:pfam00028    7 ENAPVGTEVLTVTATDPDLGPNGRIFYSIlgGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDS----GGPPLS 82

                           90
                   ....*....|
gi 2024418348 2534 NSVQVLITVL 2543
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 627-712 1.63e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 79.70  E-value: 1.63e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   627 RASDEDSPPNNQITYSIVHASAFrEYFDITvsEGYGVISVNHPLDYEQvvNGVIYLTVMAKDAGNPPLNSTVPVTIEVFD 706
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDD-GLFSID--PETGEITTTKPLDREE--QPEYTLTVEATDGGGPPLSSTATVTITVLD 75


                    ....*.
gi 2024418348   707 ENDNPP 712
Cdd:smart00112   76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
1900-1974 3.23e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 79.27  E-value: 3.23e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024418348 1900 NITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDN 1974
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDS 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2362-2443 5.77e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.16  E-value: 5.77e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2362 SAVDPDKGANGQITYELLDLSPEGYACLEDQSaGKVVANRTVDYEEVQWLNFTVRASDNGSPRRSAEIPVYLQIVDINDN 2441
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPET-GEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348  2442 NP 2443
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1261-1347 1.04e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 1.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1261 LRETAGIGTSVAVVRATDRDTGNGGLVSYQILSG-AEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGF 1339
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 2024418348 1340 CSVYVSLL 1347
Cdd:pfam00028   85 ATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 737-819 1.07e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 77.39  E-value: 1.07e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   737 NATDLDrSREYGQesIIYSLEGSS---HFRINARSGEITTTSLLDREAKSEYILIVRAVDGGVghHQKTGIAMVNITLLD 813
Cdd:smart00112    1 SATDAD-SGENGK--VTYSILSGNddgLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGG--PPLSSTATVTITVLD 75


                    ....*.
gi 2024418348   814 INDNYP 819
Cdd:smart00112   76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
2664-2753 1.56e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.34  E-value: 1.56e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2664 HIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLKTGAGNKdweyFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQP 2743
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGN----FRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|
gi 2024418348 2744 AYETMQPLQV 2753
Cdd:pfam00028   80 PLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1388-1459 9.10e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 74.69  E-value: 9.10e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024418348  1388 QITYKFDPNTNAqalSLFKINGITGVITVKGQVDREKGDFYTLTVVA-DDGGPKVDSTVKVTITVLDENDNSP 1459
Cdd:smart00112   12 KVTYSILSGNDD---GLFSIDPETGEITTTKPLDREEQPEYTLTVEAtDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1275-1353 1.53e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.53e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  1275 RATDRDTGNGGLVSYQILSG-AEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGFCSVYVSLLNELDEA 1353
Cdd:smart00112    1 SATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80
Cadherin pfam00028
Cadherin domain;
609-704 1.87e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 74.26  E-value: 1.87e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  609 YLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFReYFDITVSEgyGVISVNHPLDYEQvvNGVIYLTVMAKD 688
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGG-NFRIDPDT--GDISTTKPLDRES--IGEYELTVEATD 75

                           90
                   ....*....|....*.
gi 2024418348  689 AGNPPLNSTVPVTIEV 704
Cdd:pfam00028   76 SGGPPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 200-279 2.27e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.54  E-value: 2.27e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   200 NATDPDQGAGGSVLYSF--QPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDkNKPLSTLANLAITITDVQDM 277
Cdd:smart00112    1 SATDADSGENGKVTYSIlsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGG-GPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024418348   278 DP 279
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
719-812 5.91e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.72  E-value: 5.91e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  719 YVIAVMEDIMAGATVLFLNATDLDrsrEYGQESIIYSL---EGSSHFRINARSGEITTTSLLDREAKSEYILIVRAVDGG 795
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPD---LGPNGRIFYSIlggGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*..
gi 2024418348  796 VghHQKTGIAMVNITLL 812
Cdd:pfam00028   78 G--PPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1361-1452 7.18e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 72.33  E-value: 7.18e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 1361 YEAVIMENIPLGSEVLRVQARSID-NLN-QITYKFDPNTNAQalsLFKINGITGVITVKGQVDREKGDFYTLTVVA-DDG 1437
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDlGPNgRIFYSILGGGPGG---NFRIDPDTGDISTTKPLDRESIGEYELTVEAtDSG 77

                           90
                   ....*....|....*
gi 2024418348 1438 GPKVDSTVKVTITVL 1452
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 304-391 2.00e-14

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 70.84  E-value: 2.00e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   304 TAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENpfySSGFILTVKGTelndDRTPSNATVTTTFNILV 383
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREE---QPEYTLTVEAT----DGGGPPLSSTATVTITV 73


                    ....*...
gi 2024418348   384 IDVNDNAP 391
Cdd:smart00112   74 LDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 397-499 8.09e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 69.65  E-value: 8.09e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  397 EYSVAIPELAQVGFALpLFIQVQDKDEGPNSVFEVYLV-GNNSNHFIISPTSiqGkadiRVRVAVPLDFETIPRYEFSLF 475
Cdd:cd11304      1 SYEVSVPENAPPGTVV-LTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPST--G----EITTAKPLDREEQSSYTLTVT 73

                           90       100
                   ....*....|....*....|....*
gi 2024418348  476 ANES-IPEHVGFARVKISLINENDN 499
Cdd:cd11304     74 ATDGgGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2779-2862 1.97e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.97e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2779 SVPEHSQPGTVVGNVTgAVDADEGSNAIVYYFIAAGNRESNFQLSRE-GKLQVLRDLDREKEPYYSIIVKASSqrNWSPP 2857
Cdd:pfam00028    4 SVPENAPVGTEVLTVT-ATDPDLGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATD--SGGPP 80


                   ....*
gi 2024418348 2858 RSQRA 2862
Cdd:pfam00028   81 LSSTA 85
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2030-2110 2.24e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.76  E-value: 2.24e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2030 ALDSDQGSNAVVTYQLL-GTSPDLFIINNRTGVVSVKpgGVIDREALldPLLEFTLIALDTGG--LNSTASLTVTILDDN 2106
Cdd:smart00112    2 ATDADSGENGKVTYSILsGNDDGLFSIDPETGEITTT--KPLDREEQ--PEYTLTVEATDGGGppLSSTATVTITVLDVN 77


                    ....
gi 2024418348  2107 DNRP 2110
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
2344-2435 1.00e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 66.17  E-value: 1.00e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2344 FTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLeDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSP 2423
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRI-DPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 2024418348 2424 RRSAEIPVYLQI 2435
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
2007-2103 1.93e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 1.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2007 YQAEVMENSPAGTPVtmlnGPILALDSDQGSNAVVTYQLLGTSPD-LFIINNRTGVVSVKpgGVIDREALldPLLEFTLI 2085
Cdd:pfam00028    1 YSASVPENAPVGTEV----LTVTATDPDLGPNGRIFYSILGGGPGgNFRIDPDTGDISTT--KPLDRESI--GEYELTVE 72

                           90       100
                   ....*....|....*....|
gi 2024418348 2086 ALDTG--GLNSTASLTVTIL 2103
Cdd:pfam00028   73 ATDSGgpPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 102-175 2.33e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.06  E-value: 2.33e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   102 ARDLD---NDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIK---GTVNIQVGDVNDNAP 175
Cdd:smart00112    2 ATDADsgeNGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLsstATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 844-931 3.12e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 64.68  E-value: 3.12e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   844 VAVDPDLGENGTVVYSIRPPN--KFYSLNSTSGKIRTSGvQLDRENPNpqeaelMRRIVVSVTDCGRPPLRATssATVFV 921
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEITTTK-PLDREEQP------EYTLTVEATDGGGPPLSST--ATVTI 71

                            90
                    ....*....|
gi 2024418348   922 NLLDLNDNDP 931
Cdd:smart00112   72 TVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
286-382 4.41e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.63  E-value: 4.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  286 YSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPfysSGFILTVKGTelN 365
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESI---GEYELTVEAT--D 75

                           90
                   ....*....|....*..
gi 2024418348  366 DDRTPSNATVTTTFNIL 382
Cdd:pfam00028   76 SGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
826-921 2.86e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 62.32  E-value: 2.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  826 YFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIR--PPNKFYSLNSTSGKIRTsGVQLDRENPNpqeaelMRRIVVSV 903
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDPDTGDIST-TKPLDRESIG------EYELTVEA 73

                           90
                   ....*....|....*...
gi 2024418348  904 TDCGRPPLRATSSATVFV 921
Cdd:pfam00028   74 TDSGGPPLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
87-167 4.80e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.55  E-value: 4.80e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   87 INEDTPVGSSVTQLLARDLDNDP---LVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIK--- 160
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLsst 84


                   ....*..
gi 2024418348  161 GTVNIQV 167
Cdd:pfam00028   85 ATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2796-2891 2.52e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.29  E-value: 2.52e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2796 AVDADEGSNAIVYYFIAAGNRESNFQLSRE-GKLQVLRDLDREKEPYYSIIVKASSQRnwSPPRSqragraqhwdlstdl 2874
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGG--GPPLS--------------- 64

                            90
                    ....*....|....*..
gi 2024418348  2875 TLQEVRIFLDDINDQSP 2891
Cdd:smart00112   65 STATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 417-501 6.97e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 57.74  E-value: 6.97e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348   417 QVQDKDEGPNSVFEVYLV-GNNSNHFIISPTSIQgkadirVRVAVPLDFETIPRYEFSLFA-NESIPEHVGFARVKISLI 494
Cdd:smart00112    1 SATDADSGENGKVTYSILsGNDDGLFSIDPETGE------ITTTKPLDREEQPEYTLTVEAtDGGGPPLSSTATVTITVL 74


                    ....*..
gi 2024418348   495 NENDNRP 501
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2222-2327 9.39e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 58.08  E-value: 9.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2222 QTVSVPESATPGTVVAEVTAIDRDLHP--RLEYYLLEivarddtdalvSDQQGTFTVDFRTGAVKIKNPLNRELVATYEV 2299
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngRIFYSILG-----------GGPGGNFRIDPDTGDISTTKPLDRESIGEYEL 69

                           90       100
                   ....*....|....*....|....*...
gi 2024418348 2300 TISVHDNASEVTDRSVSVpnaklTVNVL 2327
Cdd:pfam00028   70 TVEATDSGGPPLSSTATV-----TITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2240-2334 1.05e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 54.66  E-value: 1.05e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  2240 TAIDRDLHP--RLEYYLLEivarddtdalvSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVTISVHDNASevTDRSVSV 2317
Cdd:smart00112    1 SATDADSGEngKVTYSILS-----------GNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGG--PPLSSTA 67

                            90
                    ....*....|....*..
gi 2024418348  2318 PnakLTVNVLDVNDNTP 2334
Cdd:smart00112   68 T---VTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2897-2998 9.05e-08

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 52.32  E-value: 9.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2897 EYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILgiryikqhsndSEEVANIFSIGTLDGILRTFDLFTAYNPGYFV 2976
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-----------SGNEDGLFSIDPSTGEITTAKPLDREEQSSYT 69

                           90       100
                   ....*....|....*....|....
gi 2024418348 2977 VDIMASDLVG--HNDTAIVGIYIL 2998
Cdd:cd11304     70 LTVTATDGGGppLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
398-494 1.15e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 49.22  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348  398 YSVAIPELAQVGfALPLFIQVQDKDEGPNSVFEVYLVGNNS-NHFIISPTSiqGkadiRVRVAVPLDFETIPRYEFSLFA 476
Cdd:pfam00028    1 YSASVPENAPVG-TEVLTVTATDPDLGPNGRIFYSILGGGPgGNFRIDPDT--G----DISTTKPLDRESIGEYELTVEA 73

                           90
                   ....*....|....*....
gi 2024418348  477 -NESIPEHVGFARVKISLI 494
Cdd:pfam00028   74 tDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2898-2998 1.17e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 43.44  E-value: 1.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024418348 2898 YTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILGiryikqhsndsEEVANIFSIGTLDGILRTFDLFTAYNPGYFVV 2977
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILG-----------GGPGGNFRIDPDTGDISTTKPLDRESIGEYEL 69

                           90       100
                   ....*....|....*....|...
gi 2024418348 2978 DIMASDLVGHN--DTAIVGIYIL 2998
Cdd:pfam00028   70 TVEATDSGGPPlsSTATVTITVL 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH