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Conserved domains on  [gi|2052103024|ref|XP_041909892|]
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GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [Corvus kubaryi]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADK super family cl37624
Adenylate kinase;
1-120 2.25e-60

Adenylate kinase;


The actual alignment was detected with superfamily member pfam00406:

Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 184.82  E-value: 2.25e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   1 MTQLMLNELKGLDR-YNWLLDGFPRTVAQAEALDK----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPP 75
Cdd:pfam00406  60 VVGLVKERLEQNDCkNGFLLDGFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPP 139

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2052103024  76 KVQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKK 120
Cdd:pfam00406 140 KVPGKDDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
1-120 2.25e-60

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 184.82  E-value: 2.25e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   1 MTQLMLNELKGLDR-YNWLLDGFPRTVAQAEALDK----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPP 75
Cdd:pfam00406  60 VVGLVKERLEQNDCkNGFLLDGFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPP 139

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2052103024  76 KVQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKK 120
Cdd:pfam00406 140 KVPGKDDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-129 1.57e-58

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 181.09  E-value: 1.57e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   1 MTQLMLNELKGLD-RYNWLLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSP 74
Cdd:COG0563    64 VIGLVKERLAQPDcANGFILDGFPRTVAQAEALDEllaelGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNP 143

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2052103024  75 PKVQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT 129
Cdd:COG0563   144 PKVEGVCDKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk PRK00279
adenylate kinase; Reviewed
 17-143 4.52e-58

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 179.96  E-value: 4.52e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALDKECH-----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQR 91
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLKelgikLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2052103024  92 DDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHIYAFLQ 143
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 16-143 5.71e-56

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 174.34  E-value: 5.71e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  16 NWLLDGFPRTVAQAEALDK--ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQRDD 93
Cdd:TIGR01351  80 GFILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQRED 159

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2052103024  94 DKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT-ETNKIWPHIYAFLQ 143
Cdd:TIGR01351 160 DTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 1-131 3.31e-47

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 151.62  E-value: 3.31e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   1 MTQLMLNELKGLDRYN-WLLDGFPRTVAQAEALDKECH----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLefspp 75
Cdd:cd01428    63 VIKLLKERLKKPDCKKgFILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL----- 137

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2052103024  76 kvqGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 131
Cdd:cd01428   138 ---GKDDVTGEPLSQRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
1-120 2.25e-60

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 184.82  E-value: 2.25e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   1 MTQLMLNELKGLDR-YNWLLDGFPRTVAQAEALDK----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPP 75
Cdd:pfam00406  60 VVGLVKERLEQNDCkNGFLLDGFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPP 139

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2052103024  76 KVQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKK 120
Cdd:pfam00406 140 KVPGKDDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-129 1.57e-58

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 181.09  E-value: 1.57e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   1 MTQLMLNELKGLD-RYNWLLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSP 74
Cdd:COG0563    64 VIGLVKERLAQPDcANGFILDGFPRTVAQAEALDEllaelGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNP 143

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2052103024  75 PKVQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT 129
Cdd:COG0563   144 PKVEGVCDKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk PRK00279
adenylate kinase; Reviewed
 17-143 4.52e-58

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 179.96  E-value: 4.52e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALDKECH-----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQR 91
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLKelgikLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2052103024  92 DDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHIYAFLQ 143
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 16-143 5.71e-56

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 174.34  E-value: 5.71e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  16 NWLLDGFPRTVAQAEALDK--ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQRDD 93
Cdd:TIGR01351  80 GFILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQRED 159

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2052103024  94 DKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT-ETNKIWPHIYAFLQ 143
Cdd:TIGR01351 160 DTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 1-131 3.31e-47

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 151.62  E-value: 3.31e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   1 MTQLMLNELKGLDRYN-WLLDGFPRTVAQAEALDKECH----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLefspp 75
Cdd:cd01428    63 VIKLLKERLKKPDCKKgFILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL----- 137

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2052103024  76 kvqGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 131
Cdd:cd01428   138 ---GKDDVTGEPLSQRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
PLN02674 PLN02674
adenylate kinase
 17-123 2.77e-41

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 138.09  E-value: 2.77e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALD-----KECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQR 91
Cdd:PLN02674  112 FILDGFPRTVVQAQKLDemlakQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQR 191

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2052103024  92 DDDKPETVSKRLQAYDAQTKPVLEYYRKKGLL 123
Cdd:PLN02674  192 KDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVV 223
PRK14530 PRK14530
adenylate kinase; Provisional
 17-146 1.54e-29

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 107.18  E-value: 1.54e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQRDDDKP 96
Cdd:PRK14530   85 FVLDGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQRDDDTE 164

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2052103024  97 ETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHIYAFLQTRL 146
Cdd:PRK14530  165 ETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTpDEVWADIQDAIDDAT 215
PRK14526 PRK14526
adenylate kinase; Provisional
 13-131 1.60e-20

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 83.75  E-value: 1.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  13 DRYNWLLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQRD 92
Cdd:PRK14526   77 NNDNFILDGFPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRK 156

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2052103024  93 DDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 131
Cdd:PRK14526  157 DDKEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKD 195
PRK14532 PRK14532
adenylate kinase; Provisional
 18-128 3.64e-19

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 79.48  E-value: 3.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  18 LLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARWihpasgrvynlefsppKVQGidditgeplvqRD 92
Cdd:PRK14532   82 IFDGFPRTVAQAEALDKmlasrGQKIDVVIRLKVDDEALIERIVKRF----------------EEQG-----------RP 134

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2052103024  93 DDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSG 128
Cdd:PRK14532  135 DDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDG 170
PLN02459 PLN02459
probable adenylate kinase
 18-126 9.88e-18

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 77.19  E-value: 9.88e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  18 LLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLE----FSPPKVQGIDDITGEP------ 87
Cdd:PLN02459  113 ILDGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVAdidlKGEDGRPGIVMPPLLPppecas 192

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2052103024  88 -LVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSF 126
Cdd:PLN02459  193 kLITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEF 232
adk PRK02496
adenylate kinase; Provisional
 17-131 1.55e-17

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 75.17  E-value: 1.55e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALDK---ECH--IDTVIDLDVPFETIKCRLTARwihpasgrvynlefsppkvqgidditgeplvQR 91
Cdd:PRK02496   82 WILDGFPRKVTQAAFLDEllqEIGqsGERVVNLDVPDDVVVERLLAR-------------------------------GR 130

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2052103024  92 DDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 131
Cdd:PRK02496  131 KDDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQS 170
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 58-93 2.15e-17

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 70.95  E-value: 2.15e-17
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2052103024  58 RWIHPASGRVYNLEFSPPKVQGIDDITGEPLVQRDD 93
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
PLN02842 PLN02842
nucleotide kinase
 17-117 2.67e-17

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 77.59  E-value: 2.67e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALDK-ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKvqgiDDITGEPLVQRDDDK 95
Cdd:PLN02842   79 WLLDGYPRSFAQAQSLEKlKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPE----SEEIKARLITRPDDT 154

                          90       100
                  ....*....|....*....|..
gi 2052103024  96 PETVSKRLQAYDAQTKPVLEYY 117
Cdd:PLN02842  155 EEKVKARLQIYKKNAEAILSTY 176
PRK14531 PRK14531
adenylate kinase; Provisional
 7-125 1.09e-16

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 72.92  E-value: 1.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   7 NELKGLDRYNWLLDGFPRTVAQAEALDKechidTVIDLDVPFETikcrltarwihpasgrVYNLEFSppkvqgiDDITGE 86
Cdd:PRK14531   72 SQLKALNSGGWLLDGFPRTVAQAEALEP-----LLEELKQPIEA----------------VVLLELD-------DAVLIE 123

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2052103024  87 PLVQ--RDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKS 125
Cdd:PRK14531  124 RLLArgRADDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQS 164
PRK14528 PRK14528
adenylate kinase; Provisional
 17-131 3.23e-15

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 69.27  E-value: 3.23e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALD---KECH--IDTVIDLDVPFETIKCRLTARWIhpasgrvynlefsppkVQGidditgeplvqR 91
Cdd:PRK14528   82 FLLDGFPRTVEQADALDallKNEGksIDKAINLEVPDGELLKRLLGRAE----------------IEG-----------R 134

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2052103024  92 DDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 131
Cdd:PRK14528  135 ADDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGS 174
PRK13808 PRK13808
adenylate kinase; Provisional
 17-128 5.58e-15

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 70.69  E-value: 5.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALD-----KECHIDTVIDLDVPFETIKCRLTARwihPASGRVynlefsppkvqgiddiTGEPLvqR 91
Cdd:PRK13808   81 FILDGFPRTVPQAEALDallkdKQLKLDAVVELRVNEGALLARVETR---VAEMRA----------------RGEEV--R 139

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2052103024  92 DDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSG 128
Cdd:PRK13808  140 ADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDG 176
PRK14527 PRK14527
adenylate kinase; Provisional
 4-131 6.68e-15

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 68.28  E-value: 6.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   4 LMLNELKGLDRYNWLLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARwihpasGRvynlefsppkvq 78
Cdd:PRK14527   73 LIRDELAGMEPVRVIFDGFPRTLAQAEALDRlleelGARLLAVVLLEVPDEELIRRIVER------AR------------ 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2052103024  79 gidditgepLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 131
Cdd:PRK14527  135 ---------QEGRSDDNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGT 178
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 4-129 1.79e-12

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 62.00  E-value: 1.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   4 LMLNELKGLDR-YNWLLDGFPRTVAQAEA----LDKECHIDTVIDLDVPFETIKCRLTARwiHPASGRVynlefsppkvq 78
Cdd:TIGR01359  67 LLKKAIQEDGSsKKFLIDGFPRNEENLEAweklMDNKVNFKFVLFFDCPEETMIKRLLKR--GQTSGRV----------- 133

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2052103024  79 gidditgeplvqrdDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT 129
Cdd:TIGR01359 134 --------------DDNIETLKKRFRTYNEETLPIIEHFENKGKVKEINAE 170
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 17-146 2.09e-12

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 62.51  E-value: 2.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNL------EFSPPKV---QGIDDITGEP 87
Cdd:PTZ00088   89 FILDGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIahirsdPYDMPPIlppADCEGCKGNP 168

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2052103024  88 -LVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGL-LKSFSGTETNKIWPHIYAFLQTRL 146
Cdd:PTZ00088  169 kLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNENCnLVDFEITRGLRDFDDFYRIVLQRL 229
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 17-123 1.49e-10

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 56.75  E-value: 1.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024  17 WLLDGFPRTVAQAEALDKEC-HIDTVIDLDVPFETIKCRLTARwiHPASGRVynlefsppkvqgidditgeplvqrdDDK 95
Cdd:TIGR01360  85 FLIDGYPREVKQGEEFERRIgPPTLVLYFDCSEDTMVKRLLKR--AETSGRV-------------------------DDN 137

                          90       100
                  ....*....|....*....|....*...
gi 2052103024  96 PETVSKRLQAYDAQTKPVLEYYRKKGLL 123
Cdd:TIGR01360 138 EKTIKKRLETYYKATEPVIAYYETKGKL 165
PRK14529 PRK14529
adenylate kinase; Provisional
 4-110 5.92e-08

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 50.10  E-value: 5.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   4 LMLNELKGLDRYNWLLDGFPRTVAQAEALDKECH-----IDTVIDLDVPFETIKCRLTARWI------HPAsgrvyNLEF 72
Cdd:PRK14529   67 MILETLKQDGKNGWLLDGFPRNKVQAEKLWEALQkegmkLDYVIEILLPREVAKNRIMGRRLckndnnHPN-----NIFI 141

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2052103024  73 SPPKVQG-IDDITGEPLVQRDDDKPET-VSKRLQA-YDAQT 110
Cdd:PRK14529  142 DAIKPDGdVCRVCGGELSTRADDQDEEaINKRHDIyYDTET 182
PLN02200 PLN02200
adenylate kinase family protein
 3-138 1.23e-06

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 46.42  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103024   3 QLMLNELKGLDRYNWLLDGFPRTVAQAEALDK--ECHIDTVIDLDVPFETIKCRLTARwihpASGRVynlefsppkvqgi 80
Cdd:PLN02200  109 KLIQKEMESSDNNKFLIDGFPRTEENRIAFERiiGAEPNVVLFFDCPEEEMVKRVLNR----NQGRV------------- 171

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2052103024  81 dditgeplvqrdDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHI 138
Cdd:PLN02200  172 ------------DDNIDTIKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTvDEIFEQV 218
AAA_17 pfam13207
AAA domain;
16-71 7.76e-04

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 37.60  E-value: 7.76e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2052103024  16 NWLLDGFPRTVAQAEALD-------KECHIDTVIDLDVPFETIKCRLTARwihPASGRVY-NLE 71
Cdd:pfam13207  73 GVIVDGHPRIKTPAGYLPglpvevlRELKPDAIILLEADPEEILERRLKD---RTRGRDDdSEE 133
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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