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Conserved domains on  [gi|2073954662]
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Chain Af, Ubiquitin-40S ribosomal protein S27a

Protein Classification

ribosomal S27a family protein( domain architecture ID 10482815)

ribosomal S27a family protein similar to Cenarchaeum symbiosum 30S ribosomal protein S27ae; the ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_S27 pfam01599
Ribosomal protein S27a; This family of ribosomal proteins consists mainly of the 40S ribosomal ...
 27-71 6.16e-21

Ribosomal protein S27a; This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesized as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilization and is required for efficient ribosome biogenesis. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins.


:

Pssm-ID: 460261  Cd Length: 43  Bit Score: 77.23  E-value: 6.16e-21
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 2073954662 27 LKYYKVDENGKIHRLRRECPgeNCGAGVFMAAHEDRHYCGKCNLT 71
Cdd:pfam01599  1 LKYYKVDDDGKVERLRKECP--RCGAGVFMAEHKDRHYCGKCGLT 43
 
Name Accession Description Interval E-value
Ribosomal_S27 pfam01599
Ribosomal protein S27a; This family of ribosomal proteins consists mainly of the 40S ribosomal ...
 27-71 6.16e-21

Ribosomal protein S27a; This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesized as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilization and is required for efficient ribosome biogenesis. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins.


Pssm-ID: 460261  Cd Length: 43  Bit Score: 77.23  E-value: 6.16e-21
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 2073954662 27 LKYYKVDENGKIHRLRRECPgeNCGAGVFMAAHEDRHYCGKCNLT 71
Cdd:pfam01599  1 LKYYKVDDDGKVERLRKECP--RCGAGVFMAEHKDRHYCGKCGLT 43
RPS27ae COG1998
Ribosomal protein S27AE [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
 25-71 6.85e-12

Ribosomal protein S27AE [Translation, ribosomal structure and biogenesis]; Ribosomal protein S27AE is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441601  Cd Length: 56  Bit Score: 54.63  E-value: 6.85e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2073954662 25 AVLKYYKVdENGKIHRLRRECPgeNCGAGVFMAAHEDRHYCGKCNLT 71
Cdd:COG1998    8 AVHEYYKV-EDGKIKRKRKFCP--RCGSGVFMAEHKDRWHCGKCGYT 51
PRK00432 PRK00432
30S ribosomal protein S27ae; Validated
 25-71 8.08e-07

30S ribosomal protein S27ae; Validated


Pssm-ID: 234760  Cd Length: 50  Bit Score: 41.51  E-value: 8.08e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2073954662 25 AVLKYYKVDeNGKIHRLRRECPgeNCGAGvFMAAHEDRHYCGKCNLT 71
Cdd:PRK00432   4 AKREYYEVD-GGKVKRKNKFCP--RCGSG-FMAEHLDRWHCGKCGYT 46
 
Name Accession Description Interval E-value
Ribosomal_S27 pfam01599
Ribosomal protein S27a; This family of ribosomal proteins consists mainly of the 40S ribosomal ...
 27-71 6.16e-21

Ribosomal protein S27a; This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesized as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilization and is required for efficient ribosome biogenesis. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins.


Pssm-ID: 460261  Cd Length: 43  Bit Score: 77.23  E-value: 6.16e-21
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 2073954662 27 LKYYKVDENGKIHRLRRECPgeNCGAGVFMAAHEDRHYCGKCNLT 71
Cdd:pfam01599  1 LKYYKVDDDGKVERLRKECP--RCGAGVFMAEHKDRHYCGKCGLT 43
RPS27ae COG1998
Ribosomal protein S27AE [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
 25-71 6.85e-12

Ribosomal protein S27AE [Translation, ribosomal structure and biogenesis]; Ribosomal protein S27AE is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441601  Cd Length: 56  Bit Score: 54.63  E-value: 6.85e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2073954662 25 AVLKYYKVdENGKIHRLRRECPgeNCGAGVFMAAHEDRHYCGKCNLT 71
Cdd:COG1998    8 AVHEYYKV-EDGKIKRKRKFCP--RCGSGVFMAEHKDRWHCGKCGYT 51
PRK00432 PRK00432
30S ribosomal protein S27ae; Validated
 25-71 8.08e-07

30S ribosomal protein S27ae; Validated


Pssm-ID: 234760  Cd Length: 50  Bit Score: 41.51  E-value: 8.08e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2073954662 25 AVLKYYKVDeNGKIHRLRRECPgeNCGAGvFMAAHEDRHYCGKCNLT 71
Cdd:PRK00432   4 AKREYYEVD-GGKVKRKNKFCP--RCGSG-FMAEHLDRWHCGKCGYT 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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