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Conserved domains on  [gi|216905933|ref|YP_002333561|]
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transcriptional regulator ICP4 [Equid alphaherpesvirus 9]

Protein Classification

PHA03307 family protein( domain architecture ID 11476204)

PHA03307 family protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 6-1400 0e+00

transcriptional regulator ICP4; Provisional


:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 1295.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933    6 SDFAPDLYDFIESNDFGEDPLIRAASAAEEgftqpAAPDLLYGSQGMFGVDDAPLATPAVVIPPPSPAPEP--------- 76
Cdd:PHA03307    1 SDNAPDLYDLIEAAAEGGEFFPRPPATPGD-----AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgpppgp 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933   77 ----------------------RGGKAKRSPAAGGPPTPAAAQPASPAPS----PAPGLAAMLKMV--------HSSVAP 122
Cdd:PHA03307   76 gteapanesrstptwslstlapASPAREGSPTPPGPSSPDPPPPTPPPASpppsPAPDLSEMLRPVgspgpppaASPPAA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  123 GNGRRATGSSSSGGGDAADPVALDSDTETCPGSPQPEFPPSASPGGGSPAPRVRSISISSSSSSSSSMDADDQADGAGAS 202
Cdd:PHA03307  156 GASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGAS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  203 SSSSSSSDDSDSDEGGEEETPRPRHSPDAAKTPSAAGSPGPSSGGNRPAAGAATPKSCRSGAASPGAPAPapapsrpgvG 282
Cdd:PHA03307  236 SSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGS---------G 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  283 LLPPGARILEYLEGVREANLAKTLERPEPPAGMASPPGRSPQRLPKDQRPKSALAGASKRKRANPRPIPQTQA--PIEEA 360
Cdd:PHA03307  307 PAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAasAGRPT 386

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  361 PRTASWDLLDMNSSQAASAAAAAPVAPCGP--------GFYQREPLLTPSGDPWPGSDPPPMGRVRYGGTGDSRDGLWDD 432
Cdd:PHA03307  387 RRRARAAVAGRARRRDATGRFPAGRPRPSPldagaasgAFYARYPLLTPSGEPWPGSPPPPPGRVRYGGLGDSRPGLWDA 466

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  433 PEIVLAASRYAEAQTPVPVFVPEMGDSTKQYNALVRMVFE-SREAMSWLQNSKLSGPDQNLAQFCQKFIHAPRGHGSFIT 511
Cdd:PHA03307  467 PEVREAAARYEASPGPVPVYVPEMGDSAKQYAALVRLLYTpDREAMGWLQNPKLTGPDQALDQFCQKKFQAPRGSGSFIT 546

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  512 GSVANPLPHIGDAMAAGNPLWALPHAAASVAMSRRYDRTQKSFILQSLRRAYADMAYPRDEAGRPDSHTTTAgvsagypa 591
Cdd:PHA03307  547 GSVARPVPHIGDAMAAGNALWALPHAAAAVAMSRRYDRAQKGFLLQSLRRAYAPMAYPENAADTGAGAAAPA-------- 618

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  592 qaaaaaagQQQPEPPAASvrvreaytrvcaalgprrkaaaaaaapgtrAPRPSAFRLRELGDACVLACQAVFEALLRLRG 671
Cdd:PHA03307  619 --------PAAPRPDAAA------------------------------AGGASARPLRELADACVLACRAVLEALLEGPD 660

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  672 GASAVPGLdpsEIPSPACPPEALCSNPAGLETAALSLYELRDLVERARLLGDsdPTHRLGADELRLAVRAVLVVARTVAP 751
Cdd:PHA03307  661 GLSAVPGL---AFPRPACPPRALEACPARLESWLRELRDLRDAVYLARLRGD--LPVAGGREERVAAVRAVSLVARTVAP 735

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  752 LVRYNAEGARARASAWTVTQAVFSIPSLVGGMLGEAVSLLAPPTRSQPSSSSpggegsqqPFSGSSAAEGSLPPLWPTVP 831
Cdd:PHA03307  736 LVRYSPRRARARASAWDITDALFSNPSLVPAKLAEALALLEPAEPQRGAGSS--------PPVRAEAAFRRPGRLRRSGP 807

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  832 GKQSAAAPSTHSQSPQHSQSGGSGAatatcsratqtsarsqgqQQKARSPQAAASPAHLSQEampgSSSDDRGAIVHGRP 911
Cdd:PHA03307  808 AADAASRTASKRKSRSHTPDGGSES------------------SGPARPPGAAARPPPARSS----ESSKSKPAAAGGRA 865

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  912 RGKSGKRRSEPLEPAAQAGAPAFSSSARGYDPSSGPVDSPPAPKRRVatqghqapraLGPMPAEGPDRRGGFRRVPRGDC 991
Cdd:PHA03307  866 RGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVK----------LGPMPPGGPDPRGGFRRVPPGDL 935

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  992 HTPLPSDAACAAYCPPELVAELIDHPLFPEAWRPALTFDPQALATIAARCSGPPARDGARFGELAASGPLRRRAAWMQQI 1071
Cdd:PHA03307  936 HTPAPSAAALAAYCPPEVVAELVDHPLFPEPWRPALAFDPEALAEIAARCGGPPPRSGSAFGPLRASGPLRRRAAWMRQI 1015

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1072 PDPEDVKVVVLYSPLQDEDLLGGLPaarPGGSRREPLWSDIKGGLSALLAALGNRVLTKRSHAWAGNWTGAPDVSALNAQ 1151
Cdd:PHA03307 1016 PDPEDVRVVVLYSPLPGEHLFGVPA---PDASPGGPAWSPERGGLSFLLAALGNRLCLPDSHAWAGNWTGAPDVSALNAQ 1092

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1152 GVLLLSTGDLAFTGCVEYLCLRLGSARRKLLVLDAVSSEDWPQDGPAISQYHIYMRAALTPRVACAVRWPRERHLSRAVL 1231
Cdd:PHA03307 1093 GVLLLSTRDLAFAGAVEYLCLRLGSARRRLIVLDTVDPEDWPADGPAVSQYHVYLRCAVLPRAQCAVRWPAARDLARAVL 1172

                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1232 TSSTLFGPGLFSRAEAAFARLYPDSAPLRLCRAANVAYTVDTRAGERTRVPLPPREYRQRVLPDYDGCKDMRAQAEGLGF 1311
Cdd:PHA03307 1173 TSSRVFGPGLFARVEAAFARLYPDAPPLRLCRGANVRYTVRTRLGPRTRVPLPPREYRQAVLPALDGCKDMAAQAEGLGL 1252

                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1312 HDPDFEEGAAQSHRAANRWGLGAWLRPVYLACGRRGAGAvEPSEllIPELLSEFCRVALLEPDAEAGPLVLPITEAPRR- 1390
Cdd:PHA03307 1253 GAPDFLEGEAHSHRAANRWGLGAPLRPVYLAEGRRAAIA-GPDE--LPAVVRAFCRAALLEPDPEAPPLVLPPSAAAEAa 1329

                        1450
                  ....*....|..
gi 216905933 1391 --RAPRVDWEPG 1400
Cdd:PHA03307 1330 haRAPRVTWAKS 1341
 
Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 6-1400 0e+00

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 1295.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933    6 SDFAPDLYDFIESNDFGEDPLIRAASAAEEgftqpAAPDLLYGSQGMFGVDDAPLATPAVVIPPPSPAPEP--------- 76
Cdd:PHA03307    1 SDNAPDLYDLIEAAAEGGEFFPRPPATPGD-----AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgpppgp 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933   77 ----------------------RGGKAKRSPAAGGPPTPAAAQPASPAPS----PAPGLAAMLKMV--------HSSVAP 122
Cdd:PHA03307   76 gteapanesrstptwslstlapASPAREGSPTPPGPSSPDPPPPTPPPASpppsPAPDLSEMLRPVgspgpppaASPPAA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  123 GNGRRATGSSSSGGGDAADPVALDSDTETCPGSPQPEFPPSASPGGGSPAPRVRSISISSSSSSSSSMDADDQADGAGAS 202
Cdd:PHA03307  156 GASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGAS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  203 SSSSSSSDDSDSDEGGEEETPRPRHSPDAAKTPSAAGSPGPSSGGNRPAAGAATPKSCRSGAASPGAPAPapapsrpgvG 282
Cdd:PHA03307  236 SSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGS---------G 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  283 LLPPGARILEYLEGVREANLAKTLERPEPPAGMASPPGRSPQRLPKDQRPKSALAGASKRKRANPRPIPQTQA--PIEEA 360
Cdd:PHA03307  307 PAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAasAGRPT 386

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  361 PRTASWDLLDMNSSQAASAAAAAPVAPCGP--------GFYQREPLLTPSGDPWPGSDPPPMGRVRYGGTGDSRDGLWDD 432
Cdd:PHA03307  387 RRRARAAVAGRARRRDATGRFPAGRPRPSPldagaasgAFYARYPLLTPSGEPWPGSPPPPPGRVRYGGLGDSRPGLWDA 466

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  433 PEIVLAASRYAEAQTPVPVFVPEMGDSTKQYNALVRMVFE-SREAMSWLQNSKLSGPDQNLAQFCQKFIHAPRGHGSFIT 511
Cdd:PHA03307  467 PEVREAAARYEASPGPVPVYVPEMGDSAKQYAALVRLLYTpDREAMGWLQNPKLTGPDQALDQFCQKKFQAPRGSGSFIT 546

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  512 GSVANPLPHIGDAMAAGNPLWALPHAAASVAMSRRYDRTQKSFILQSLRRAYADMAYPRDEAGRPDSHTTTAgvsagypa 591
Cdd:PHA03307  547 GSVARPVPHIGDAMAAGNALWALPHAAAAVAMSRRYDRAQKGFLLQSLRRAYAPMAYPENAADTGAGAAAPA-------- 618

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  592 qaaaaaagQQQPEPPAASvrvreaytrvcaalgprrkaaaaaaapgtrAPRPSAFRLRELGDACVLACQAVFEALLRLRG 671
Cdd:PHA03307  619 --------PAAPRPDAAA------------------------------AGGASARPLRELADACVLACRAVLEALLEGPD 660

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  672 GASAVPGLdpsEIPSPACPPEALCSNPAGLETAALSLYELRDLVERARLLGDsdPTHRLGADELRLAVRAVLVVARTVAP 751
Cdd:PHA03307  661 GLSAVPGL---AFPRPACPPRALEACPARLESWLRELRDLRDAVYLARLRGD--LPVAGGREERVAAVRAVSLVARTVAP 735

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  752 LVRYNAEGARARASAWTVTQAVFSIPSLVGGMLGEAVSLLAPPTRSQPSSSSpggegsqqPFSGSSAAEGSLPPLWPTVP 831
Cdd:PHA03307  736 LVRYSPRRARARASAWDITDALFSNPSLVPAKLAEALALLEPAEPQRGAGSS--------PPVRAEAAFRRPGRLRRSGP 807

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  832 GKQSAAAPSTHSQSPQHSQSGGSGAatatcsratqtsarsqgqQQKARSPQAAASPAHLSQEampgSSSDDRGAIVHGRP 911
Cdd:PHA03307  808 AADAASRTASKRKSRSHTPDGGSES------------------SGPARPPGAAARPPPARSS----ESSKSKPAAAGGRA 865

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  912 RGKSGKRRSEPLEPAAQAGAPAFSSSARGYDPSSGPVDSPPAPKRRVatqghqapraLGPMPAEGPDRRGGFRRVPRGDC 991
Cdd:PHA03307  866 RGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVK----------LGPMPPGGPDPRGGFRRVPPGDL 935

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  992 HTPLPSDAACAAYCPPELVAELIDHPLFPEAWRPALTFDPQALATIAARCSGPPARDGARFGELAASGPLRRRAAWMQQI 1071
Cdd:PHA03307  936 HTPAPSAAALAAYCPPEVVAELVDHPLFPEPWRPALAFDPEALAEIAARCGGPPPRSGSAFGPLRASGPLRRRAAWMRQI 1015

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1072 PDPEDVKVVVLYSPLQDEDLLGGLPaarPGGSRREPLWSDIKGGLSALLAALGNRVLTKRSHAWAGNWTGAPDVSALNAQ 1151
Cdd:PHA03307 1016 PDPEDVRVVVLYSPLPGEHLFGVPA---PDASPGGPAWSPERGGLSFLLAALGNRLCLPDSHAWAGNWTGAPDVSALNAQ 1092

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1152 GVLLLSTGDLAFTGCVEYLCLRLGSARRKLLVLDAVSSEDWPQDGPAISQYHIYMRAALTPRVACAVRWPRERHLSRAVL 1231
Cdd:PHA03307 1093 GVLLLSTRDLAFAGAVEYLCLRLGSARRRLIVLDTVDPEDWPADGPAVSQYHVYLRCAVLPRAQCAVRWPAARDLARAVL 1172

                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1232 TSSTLFGPGLFSRAEAAFARLYPDSAPLRLCRAANVAYTVDTRAGERTRVPLPPREYRQRVLPDYDGCKDMRAQAEGLGF 1311
Cdd:PHA03307 1173 TSSRVFGPGLFARVEAAFARLYPDAPPLRLCRGANVRYTVRTRLGPRTRVPLPPREYRQAVLPALDGCKDMAAQAEGLGL 1252

                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1312 HDPDFEEGAAQSHRAANRWGLGAWLRPVYLACGRRGAGAvEPSEllIPELLSEFCRVALLEPDAEAGPLVLPITEAPRR- 1390
Cdd:PHA03307 1253 GAPDFLEGEAHSHRAANRWGLGAPLRPVYLAEGRRAAIA-GPDE--LPAVVRAFCRAALLEPDPEAPPLVLPPSAAAEAa 1329

                        1450
                  ....*....|..
gi 216905933 1391 --RAPRVDWEPG 1400
Cdd:PHA03307 1330 haRAPRVTWAKS 1341
Herpes_ICP4_C pfam03585
Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 ...
 981-1406 1.77e-149

Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the C-terminal region that probably acts as an enhancer for the N-terminal region.


Pssm-ID: 281570  Cd Length: 444  Bit Score: 462.54  E-value: 1.77e-149
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933   981 GGFRRVPRGDCHTPLPSDAACAAYCPPELVAELIDHPLFPEAWRPALTFDPQALATIAARCSGP-------------PAR 1047
Cdd:pfam03585    1 GGFRRFPVGTVHTQTPPQSALNAYCPPGAFAELVDFPLFPEPWRPALRFDPEALADIAARVANAlpgggdynsneiiTSA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1048 DGARFGELAASGPLRRRAAWMQQIPDPEDVKVVVLYSPLQDEDLLGGLPAARPggsrrePLWSDIKGGLSALLAALGNRV 1127
Cdd:pfam03585   81 ASRAFGPPTATSKLRRRTAWMRQIPDPEDVRIVVLYSPLPGEDLFCVPAPDTP------PKWSNKRGGLSFLLAALSNRL 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1128 LTKRSHAWAGNWTGAPDVSALNAQGVLLLSTGDLAFTGCVEYLCLRLGSARRKLLVLDAVSSEDWPQDGPAISQYHIYMR 1207
Cdd:pfam03585  155 CLPKTSAWAGNWTGAPDVSALTAMGVLLLSTRDLAFAGAVEYLGRQCMKRKRRLIVMDTVEDRYWPPDGPAISEEHTYMK 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1208 AALTPRVACAVRWPRERHLSRAVLTSSTLFGPGLFSRAEAAFARLYPDSAPLRLCRAANVAYTVDTRAGERTRVPLPPRE 1287
Cdd:pfam03585  235 CIISPRSQCCVRWPGLLDLGRTVIASRRVFGPLTFARLEQAYAELYPEDSPLNLCRGGNVRYTVETRLGPVTCVPTSPRE 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1288 YRQRVLPDYDGCKDMRAQAEGLGFHDPDFEEGAAQSHRAANRWGLGAWLRPVYLACGRRgAGAVEPSELLIPElLSEFCR 1367
Cdd:pfam03585  315 YRAAVLPVFDGCKDLARQSRGLGLGAPDFLCEEAHSHRAARRWGLGAPLRPVYVIEGRM-NAIAGPSFLHVPT-ARNFCR 392

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 216905933  1368 VALLEPDAEAGPLVLPITEAP------------RRRAPRVDWEPGFGSRST 1406
Cdd:pfam03585  393 SALLEPDPEARPLVLHIPEGTcsalaedmvasaLPPCPRITWGQGFGHEEG 443
 
Name Accession Description Interval E-value
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 6-1400 0e+00

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 1295.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933    6 SDFAPDLYDFIESNDFGEDPLIRAASAAEEgftqpAAPDLLYGSQGMFGVDDAPLATPAVVIPPPSPAPEP--------- 76
Cdd:PHA03307    1 SDNAPDLYDLIEAAAEGGEFFPRPPATPGD-----AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgpppgp 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933   77 ----------------------RGGKAKRSPAAGGPPTPAAAQPASPAPS----PAPGLAAMLKMV--------HSSVAP 122
Cdd:PHA03307   76 gteapanesrstptwslstlapASPAREGSPTPPGPSSPDPPPPTPPPASpppsPAPDLSEMLRPVgspgpppaASPPAA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  123 GNGRRATGSSSSGGGDAADPVALDSDTETCPGSPQPEFPPSASPGGGSPAPRVRSISISSSSSSSSSMDADDQADGAGAS 202
Cdd:PHA03307  156 GASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGAS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  203 SSSSSSSDDSDSDEGGEEETPRPRHSPDAAKTPSAAGSPGPSSGGNRPAAGAATPKSCRSGAASPGAPAPapapsrpgvG 282
Cdd:PHA03307  236 SSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGS---------G 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  283 LLPPGARILEYLEGVREANLAKTLERPEPPAGMASPPGRSPQRLPKDQRPKSALAGASKRKRANPRPIPQTQA--PIEEA 360
Cdd:PHA03307  307 PAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAasAGRPT 386

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  361 PRTASWDLLDMNSSQAASAAAAAPVAPCGP--------GFYQREPLLTPSGDPWPGSDPPPMGRVRYGGTGDSRDGLWDD 432
Cdd:PHA03307  387 RRRARAAVAGRARRRDATGRFPAGRPRPSPldagaasgAFYARYPLLTPSGEPWPGSPPPPPGRVRYGGLGDSRPGLWDA 466

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  433 PEIVLAASRYAEAQTPVPVFVPEMGDSTKQYNALVRMVFE-SREAMSWLQNSKLSGPDQNLAQFCQKFIHAPRGHGSFIT 511
Cdd:PHA03307  467 PEVREAAARYEASPGPVPVYVPEMGDSAKQYAALVRLLYTpDREAMGWLQNPKLTGPDQALDQFCQKKFQAPRGSGSFIT 546

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  512 GSVANPLPHIGDAMAAGNPLWALPHAAASVAMSRRYDRTQKSFILQSLRRAYADMAYPRDEAGRPDSHTTTAgvsagypa 591
Cdd:PHA03307  547 GSVARPVPHIGDAMAAGNALWALPHAAAAVAMSRRYDRAQKGFLLQSLRRAYAPMAYPENAADTGAGAAAPA-------- 618

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  592 qaaaaaagQQQPEPPAASvrvreaytrvcaalgprrkaaaaaaapgtrAPRPSAFRLRELGDACVLACQAVFEALLRLRG 671
Cdd:PHA03307  619 --------PAAPRPDAAA------------------------------AGGASARPLRELADACVLACRAVLEALLEGPD 660

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  672 GASAVPGLdpsEIPSPACPPEALCSNPAGLETAALSLYELRDLVERARLLGDsdPTHRLGADELRLAVRAVLVVARTVAP 751
Cdd:PHA03307  661 GLSAVPGL---AFPRPACPPRALEACPARLESWLRELRDLRDAVYLARLRGD--LPVAGGREERVAAVRAVSLVARTVAP 735

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  752 LVRYNAEGARARASAWTVTQAVFSIPSLVGGMLGEAVSLLAPPTRSQPSSSSpggegsqqPFSGSSAAEGSLPPLWPTVP 831
Cdd:PHA03307  736 LVRYSPRRARARASAWDITDALFSNPSLVPAKLAEALALLEPAEPQRGAGSS--------PPVRAEAAFRRPGRLRRSGP 807

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  832 GKQSAAAPSTHSQSPQHSQSGGSGAatatcsratqtsarsqgqQQKARSPQAAASPAHLSQEampgSSSDDRGAIVHGRP 911
Cdd:PHA03307  808 AADAASRTASKRKSRSHTPDGGSES------------------SGPARPPGAAARPPPARSS----ESSKSKPAAAGGRA 865

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  912 RGKSGKRRSEPLEPAAQAGAPAFSSSARGYDPSSGPVDSPPAPKRRVatqghqapraLGPMPAEGPDRRGGFRRVPRGDC 991
Cdd:PHA03307  866 RGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVK----------LGPMPPGGPDPRGGFRRVPPGDL 935

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  992 HTPLPSDAACAAYCPPELVAELIDHPLFPEAWRPALTFDPQALATIAARCSGPPARDGARFGELAASGPLRRRAAWMQQI 1071
Cdd:PHA03307  936 HTPAPSAAALAAYCPPEVVAELVDHPLFPEPWRPALAFDPEALAEIAARCGGPPPRSGSAFGPLRASGPLRRRAAWMRQI 1015

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1072 PDPEDVKVVVLYSPLQDEDLLGGLPaarPGGSRREPLWSDIKGGLSALLAALGNRVLTKRSHAWAGNWTGAPDVSALNAQ 1151
Cdd:PHA03307 1016 PDPEDVRVVVLYSPLPGEHLFGVPA---PDASPGGPAWSPERGGLSFLLAALGNRLCLPDSHAWAGNWTGAPDVSALNAQ 1092

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1152 GVLLLSTGDLAFTGCVEYLCLRLGSARRKLLVLDAVSSEDWPQDGPAISQYHIYMRAALTPRVACAVRWPRERHLSRAVL 1231
Cdd:PHA03307 1093 GVLLLSTRDLAFAGAVEYLCLRLGSARRRLIVLDTVDPEDWPADGPAVSQYHVYLRCAVLPRAQCAVRWPAARDLARAVL 1172

                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1232 TSSTLFGPGLFSRAEAAFARLYPDSAPLRLCRAANVAYTVDTRAGERTRVPLPPREYRQRVLPDYDGCKDMRAQAEGLGF 1311
Cdd:PHA03307 1173 TSSRVFGPGLFARVEAAFARLYPDAPPLRLCRGANVRYTVRTRLGPRTRVPLPPREYRQAVLPALDGCKDMAAQAEGLGL 1252

                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933 1312 HDPDFEEGAAQSHRAANRWGLGAWLRPVYLACGRRGAGAvEPSEllIPELLSEFCRVALLEPDAEAGPLVLPITEAPRR- 1390
Cdd:PHA03307 1253 GAPDFLEGEAHSHRAANRWGLGAPLRPVYLAEGRRAAIA-GPDE--LPAVVRAFCRAALLEPDPEAPPLVLPPSAAAEAa 1329

                        1450
                  ....*....|..
gi 216905933 1391 --RAPRVDWEPG 1400
Cdd:PHA03307 1330 haRAPRVTWAKS 1341
Herpes_ICP4_C pfam03585
Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 ...
 981-1406 1.77e-149

Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the C-terminal region that probably acts as an enhancer for the N-terminal region.


Pssm-ID: 281570  Cd Length: 444  Bit Score: 462.54  E-value: 1.77e-149
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933   981 GGFRRVPRGDCHTPLPSDAACAAYCPPELVAELIDHPLFPEAWRPALTFDPQALATIAARCSGP-------------PAR 1047
Cdd:pfam03585    1 GGFRRFPVGTVHTQTPPQSALNAYCPPGAFAELVDFPLFPEPWRPALRFDPEALADIAARVANAlpgggdynsneiiTSA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1048 DGARFGELAASGPLRRRAAWMQQIPDPEDVKVVVLYSPLQDEDLLGGLPAARPggsrrePLWSDIKGGLSALLAALGNRV 1127
Cdd:pfam03585   81 ASRAFGPPTATSKLRRRTAWMRQIPDPEDVRIVVLYSPLPGEDLFCVPAPDTP------PKWSNKRGGLSFLLAALSNRL 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1128 LTKRSHAWAGNWTGAPDVSALNAQGVLLLSTGDLAFTGCVEYLCLRLGSARRKLLVLDAVSSEDWPQDGPAISQYHIYMR 1207
Cdd:pfam03585  155 CLPKTSAWAGNWTGAPDVSALTAMGVLLLSTRDLAFAGAVEYLGRQCMKRKRRLIVMDTVEDRYWPPDGPAISEEHTYMK 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1208 AALTPRVACAVRWPRERHLSRAVLTSSTLFGPGLFSRAEAAFARLYPDSAPLRLCRAANVAYTVDTRAGERTRVPLPPRE 1287
Cdd:pfam03585  235 CIISPRSQCCVRWPGLLDLGRTVIASRRVFGPLTFARLEQAYAELYPEDSPLNLCRGGNVRYTVETRLGPVTCVPTSPRE 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  1288 YRQRVLPDYDGCKDMRAQAEGLGFHDPDFEEGAAQSHRAANRWGLGAWLRPVYLACGRRgAGAVEPSELLIPElLSEFCR 1367
Cdd:pfam03585  315 YRAAVLPVFDGCKDLARQSRGLGLGAPDFLCEEAHSHRAARRWGLGAPLRPVYVIEGRM-NAIAGPSFLHVPT-ARNFCR 392

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 216905933  1368 VALLEPDAEAGPLVLPITEAP------------RRRAPRVDWEPGFGSRST 1406
Cdd:pfam03585  393 SALLEPDPEARPLVLHIPEGTcsalaedmvasaLPPCPRITWGQGFGHEEG 443
Herpes_ICP4_N pfam03584
Herpesvirus ICP4-like protein N-terminal region; The immediate-early protein ICP4 ...
 411-569 3.01e-60

Herpesvirus ICP4-like protein N-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the N-terminal region that contains sites for DNA binding and homodimerization.


Pssm-ID: 367571 [Multi-domain]  Cd Length: 163  Bit Score: 203.90  E-value: 3.01e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933   411 PPPMGRVRYGGTGDSRDGLWDDPEIVLAASRYAEAQTPVPVFVPEMGDSTKQYNALVRMVFE-SREAMSWLQNSKLSGPD 489
Cdd:pfam03584    1 PPPPGRVLYGGLGDSRPGLWGAPEVREARARFEASGAPAPVYVPELGDAAQQYAALVNLLYTpDAEPLGWLQNPRLNPGD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933   490 QNLAQFCQKFIHAPRGHGSFITGSVANPLPHIGDAMAAGNPLWALPHAAASVAMSRRYDRTQKSFILQSLRRAYADMAYP 569
Cdd:pfam03584   81 VALNQICQKISGAARNSGSAVTGSVARAVPHIGYAMAAGRALWALPHAAAAVAMSRRYDRAQKTFLLTSLRRAYAPLAFP 160
PHA03308 PHA03308
transcriptional regulator ICP4; Provisional
 411-569 4.01e-12

transcriptional regulator ICP4; Provisional


Pssm-ID: 165563 [Multi-domain]  Cd Length: 1463  Bit Score: 71.38  E-value: 4.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  411 PPPMGRVrYGGTGdSRDGLWDDPEIVLAASRYAEAQTPVPVFVPEMGDSTKQYNALVR--MVFESREAMSWLQNSKLSGP 488
Cdd:PHA03308  358 PPSRGQV-YHGSG-YRQSLVDDPQVREAAAEFHANPKSASVYLEEYGMPVEQLERLVEefMVHPLSRVSYGYGGPKLSPR 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  489 DQNLAQFCqkfihAPRGHGSFITG----SVANPLPHIGDAMAAGNPLWALPHAAASVAMSRRYDRTQKSFILQSLRRAYA 564
Cdd:PHA03308  436 DKRLCELC-----ALRGPGSSEGGlsrsAVPTCLPHVAHAMRDGRVSLALPHLTELVRVCRRYDHPQKTYLLAALRRAFV 510


                  ....*
gi 216905933  565 DMAYP 569
Cdd:PHA03308  511 PFVFP 515
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 411-569 1.37e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 56.79  E-value: 1.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  411 PPPMGRVRYGGTGdSRDGLWDDPEIVLAASRYAEAQTPVPVFVPEMGDSTKQYNALVRMVFE---SREAMSWlQNSKLSG 487
Cdd:PHA03309  632 PPAADYVYYGKTG-YRPSMAAHPDVRRAAEEFSASDAAARVYVEEFGMAVEQHERLVAEFMLqplSRVSHSY-GGSRLNK 709

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  488 PDQNLAQFCQK-----------FIHAPRGHGSFITG--SVANPLPHIGDAMAAGNPLWALPHAAASVAMSRRYDRTQKSF 554
Cdd:PHA03309  710 TEKNLCKICLPpdggddrdgggKSRGGRGGGSKDASrtAMATGVPHIVHAMRDGRAALALPHLMDVIRVCRRYDASQKTY 789

                         170
                  ....*....|....*
gi 216905933  555 ILQSLRRAYADMAYP 569
Cdd:PHA03309  790 LLSCLRLAFAPLVFP 804
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 833-1023 1.75e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 46.01  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  833 KQSAAAPSthsQSPQHSQSGGSGAATATCSRATQTSARSQGQQQKARSPQAAASPAHlsqEAMPGSSSDDRGAIVhgRPR 912
Cdd:PRK07994  362 AAPLPEPE---VPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPL---PETTSQLLAARQQLQ--RAQ 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  913 GKSGKRRSEPlePAAQAGAPAFSSSARGYDPSSGPVDSPPAPKRRVAtqghQAPRALGPMPAEGPDRrggfrrvprgdcH 992
Cdd:PRK07994  434 GATKAKKSEP--AAASRARPVNSALERLASVRPAPSALEKAPAKKEA----YRWKATNPVEVKKEPV------------A 495

                         170       180       190
                  ....*....|....*....|....*....|.
gi 216905933  993 TPLPSDAACAAYCPPELVAELIDHPLFPEAW 1023
Cdd:PRK07994  496 TPKALKKALEHEKTPELAAKLAAEAIERDPW 526
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 854-990 2.62e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.39  E-value: 2.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  854 SGAATATCSRATQTSARSQGQQQkARSPQAAASPAHLSQEAMPGSSSddrgAIVHGRPRGKSGKRRSEPLEPAAQAGAPA 933
Cdd:PRK14951  367 AAAAEAAAPAEKKTPARPEAAAP-AAAPVAQAAAAPAPAAAPAAAAS----APAAPPAAAPPAPVAAPAAAAPAAAPAAA 441

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 216905933  934 FSSSARGYDPSSGPVDSPPAPKRRVATQGHQAPRALGPMPAEGPDRRggfRRVPRGD 990
Cdd:PRK14951  442 PAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARL---TPTEEGD 495
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 569-975 2.72e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  569 PRDEAGRPDSHTTTAGVSAGYPAQAAAAAAGQQQPEPPAASVRVREAYTRVCAAlgprrkaaaaaAAPGTRAPRPSAFRL 648
Cdd:PRK07764  379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPA-----------PAPAPAPAPPSPAGN 447

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  649 RELGDACVLACQAVFEALLRLRGGASAVPGLDPSEIPSPACPPEALCSNPAGLETAALSLY---------ELRDLVERAR 719
Cdd:PRK07764  448 APAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDaatlrerwpEILAAVPKRS 527

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  720 LLgdsdpTHRLGADELRLA-VRA-VLVVARTVAPLVRYNAEGARARA----------SAWTVTQAVFSIPSLVGGMLGEA 787
Cdd:PRK07764  528 RK-----TWAILLPEATVLgVRGdTLVLGFSTGGLARRFASPGNAEVlvtalaeelgGDWQVEAVVGPAPGAAGGEGPPA 602

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  788 VSLLAPPTRSQPSSSSPGGEGSQQPFSGSSAAEGSlPPLWPTVPGKQSAAAPSTHSQSPQHSQSGGSGAATATCSRATQT 867
Cdd:PRK07764  603 PASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA-EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAP 681

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  868 SARSQGQQQKARSPQAAASPAHLSQEAMPGSSSDDRgaivhgRPRGKSGKRRSEPLEPAAQAGAPAFSSSARGYDPSSGP 947
Cdd:PRK07764  682 PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDP------AAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAP 755

                         410       420
                  ....*....|....*....|....*...
gi 216905933  948 VDSPPAPKRRVATQGHQAPRALGPMPAE 975
Cdd:PRK07764  756 AQPPPPPAPAPAAAPAAAPPPSPPSEEE 783
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 814-1000 3.56e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 3.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  814 SGSSAAEGSLPPLWPTVPGKQSA-AAPSTHSQSPQHSQSGGSGAATATCSRATQTSARSQGQQQKARSPQAAASPAHLSQ 892
Cdd:PRK07764  592 PGAAGGEGPPAPASSGPPEEAARpAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPA 671

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  893 EAMPGSSSDDRGAIVHGRPRGKSGKRRSEPLEPAAQAGAPAFSSSARGYDPSSGPVDSPPAPKRRVATQGHQAPR---AL 969
Cdd:PRK07764  672 KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDdppDP 751

                         170       180       190
                  ....*....|....*....|....*....|.
gi 216905933  970 GPMPAEGPDRRGGFRRVPRGDCHTPLPSDAA 1000
Cdd:PRK07764  752 AGAPAQPPPPPAPAPAAAPAAAPPPSPPSEE 782
PHA03247 PHA03247
large tegument protein UL36; Provisional
 146-410 4.68e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 4.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  146 DSDTETCPGSPQPEFPPSASPGGGSPAPRVRSISISSSSSSSSSMDADDQADGAGASSSSSSSSDDSDSDEGGEEETPRP 225
Cdd:PHA03247 2606 GDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRR 2685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  226 RHSPDAAKTPSAAGSPGPSSGGNRPAAGAATPKSCRSGAASPGAPAPAPAPSRPGVGLLPPGArileylegVREANLAKT 305
Cdd:PHA03247 2686 RAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGP--------ATPGGPARP 2757

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 216905933  306 LERPEPPAGMASPPGRSPQRLPKDQRPKSALAGASKRKRANPRPIPQTQAPIEEAPRTASWDLLDMNSSQAASAAAAAPV 385
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837

                         250       260
                  ....*....|....*....|....*
gi 216905933  386 APCGPGFYQrEPLLTPSGDPWPGSD 410
Cdd:PHA03247 2838 APPPPPGPP-PPSLPLGGSVAPGGD 2861
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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