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Conserved domains on  [gi|23344006|gb|AAN28315|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Phalanger sericeus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 7.87e-153

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 433.12  E-value: 7.87e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQWHHQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 23344006  321 KTTNIIPPLTIISS 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 7.87e-153

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 433.12  E-value: 7.87e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQWHHQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 23344006  321 KTTNIIPPLTIISS 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.09e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.75  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    23 SSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWTLSQISDQTSSTI---- 97
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    98 -------MTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILL-TWQKIAP-----TSLMYQISPSLNMKILITMALLSTIL 164
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   165 GGWGGLNQIHLRKILAYSSITHMGWMIIIILINPT---------LTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIygiqaaifhLLTHGLFSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 23344006   236 KSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-298 4.25e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 87.86  E-value: 4.25e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   4 YILLMLSTsilLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYP-NHPRATESAIKYFLTQTTASMMLMFAIinnAWM-- 80
Cdd:COG1007 105 YALLLFAT---LGMMLMASANDLLTLFLGLELLSLSLYVLVAFRrDDRRSSEAALKYFLLGALSSGFLLYGI---SLLyg 178

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  81 -TNQWTLSQIS-----DQTSSTIMTLALAM-------KLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTS----LMY 143
Cdd:COG1007 179 aTGSLNLAGIAaalaaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLV 258

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 144 QISPSLNM---KILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITT--------- 211
Cdd:COG1007 259 EAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAylfmnlgaf 338

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 212 TLTLFLALNHSSTTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLF 291
Cdd:COG1007 339 AVILLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAY 418


                ....*..
gi 23344006 292 FYMRIIY 298
Cdd:COG1007 419 YYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-297 3.63e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 73.06  E-value: 3.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006     4 YILLMLStsiLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTN 82
Cdd:TIGR01770 105 YILLLFA---LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLkRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    83 QWTLSQISDQTSST------------IMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSL- 149
Cdd:TIGR01770 182 SLNFEDLLLFLSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIl 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   150 ------NMKILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLN----------LFTYITTTL 213
Cdd:TIGR01770 262 fgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlfyifiyalMSLGAFGVL 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   214 TLFLALNHSSTTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFY 293
Cdd:TIGR01770 342 SLLRSYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYY 421


                  ....
gi 23344006   294 MRII 297
Cdd:TIGR01770 422 LRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 7.87e-153

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 433.12  E-value: 7.87e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQWHHQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 23344006  321 KTTNIIPPLTIISS 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-333 2.22e-119

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 348.33  E-value: 2.22e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSlNMKILITMALL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQWHHQQT 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330
                 ....*....|...
gi 23344006  321 KTTNIIPPLTIIS 333
Cdd:MTH00135 320 QLTLPLAISTTAT 332
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-333 2.09e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 322.93  E-value: 2.09e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQWHHQQT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330
                 ....*....|...
gi 23344006  321 KTTnIIPPLTIIS 333
Cdd:MTH00112 321 KNT-LTATLTTLS 332
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-333 3.02e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 322.64  E-value: 3.02e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQWHHqQT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330
                 ....*....|...
gi 23344006  321 KTTNIIPPLTIIS 333
Cdd:MTH00070 320 KTNNLLSLTIILS 332
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-315 6.19e-84

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 257.97  E-value: 6.19e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQW 315
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW 315
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-306 6.38e-75

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 234.82  E-value: 6.38e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFP 306
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFP 306
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-312 1.58e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 168.85  E-value: 1.58e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNqwtlsqISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQIspsLNMKILITMALL 160
Cdd:MTH00160  82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSK 312
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNL 304
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-315 7.70e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 166.60  E-value: 7.70e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILlGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWM 80
Cdd:MTH00144   2 SSPSNLLFLFLMVM-GTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTlsqisdqtSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNM-KILITMAL 159
Cdd:MTH00144  81 SFSWF--------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISV 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  160 LSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLwNKSTP 239
Cdd:MTH00144 153 LSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYK 231

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 23344006  240 MTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTMFPSTNNSKLQW 315
Cdd:MTH00144 232 TGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-304 1.71e-38

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 139.53  E-value: 1.71e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    1 MSPYILLMLSTSILlGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAiinnawM 80
Cdd:MTH00011   4 TFPTMFLFSSTMTL-GTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLG------M 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   81 TNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKILITMALL 160
Cdd:MTH00011  77 TMMWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAM 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  161 STILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPM 240
Cdd:MTH00011 157 SALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTT 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 23344006  241 TIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTTTLTM 304
Cdd:MTH00011 237 SMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLS 300
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-300 5.26e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 124.78  E-value: 5.26e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    8 MLSTSILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMfaiinnawMTNQWTLS 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLL--------MGGSLSFS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   88 QISDQTSSTIMT-LALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPtsLMYQISPSLNMKILITMALLSTILGG 166
Cdd:MTH00197  74 NLYLSLLSVVLViLGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  167 WGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWNKSTPMTIVIII 246
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 23344006  247 TLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYTT 300
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 2.66e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 90.47  E-value: 2.66e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   13 ILLGTSLTLFSSHWLTAWMGLEINTLAI-IPMMTYPNHPRATESAIKYFLTQTTASMMLMFAI-------------INNA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCallcgttgglhlsYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   79 WMTNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMkiLITMA 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNI--LLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  159 LLSTILGGWGGLNQIHLRKILAYSSITHMGWMII------IILINPTLTLLNLFTYITTTLTLFLALNHSSTTKIKSLAN 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWgieigsFESIQASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSG 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 23344006  233 LWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRII 297
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.09e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.75  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    23 SSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWTLSQISDQTSSTI---- 97
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    98 -------MTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILL-TWQKIAP-----TSLMYQISPSLNMKILITMALLSTIL 164
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   165 GGWGGLNQIHLRKILAYSSITHMGWMIIIILINPT---------LTLLNLFTYITTTLTLFLALNHSSTTKIKSLANLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIygiqaaifhLLTHGLFSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 23344006   236 KSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-298 4.25e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 87.86  E-value: 4.25e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   4 YILLMLSTsilLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYP-NHPRATESAIKYFLTQTTASMMLMFAIinnAWM-- 80
Cdd:COG1007 105 YALLLFAT---LGMMLMASANDLLTLFLGLELLSLSLYVLVAFRrDDRRSSEAALKYFLLGALSSGFLLYGI---SLLyg 178

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  81 -TNQWTLSQIS-----DQTSSTIMTLALAM-------KLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTS----LMY 143
Cdd:COG1007 179 aTGSLNLAGIAaalaaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLV 258

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 144 QISPSLNM---KILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITT--------- 211
Cdd:COG1007 259 EAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAylfmnlgaf 338

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 212 TLTLFLALNHSSTTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLF 291
Cdd:COG1007 339 AVILLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAY 418


                ....*..
gi 23344006 292 FYMRIIY 298
Cdd:COG1007 419 YYLRVVK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-297 4.44e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 84.87  E-value: 4.44e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    4 YILLMLSTsilLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPN-HPRATESAIKYFLTQTTASMMLMFAIINNAWMTN 82
Cdd:PRK05777 106 YLLVLFAL---LGMMVMVSANDLLTLFLGLELLSLPLYALAALRRdRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATG 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   83 QWTLSQISDQTSSTI------------MTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAP----TSLMYQIS 146
Cdd:PRK05777 183 SLSFAGIAKALADGSgnsllllfglvfLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfavlLRLLVVAF 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  147 PSLNMK---ILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITT---------TLT 214
Cdd:PRK05777 263 GGLSEDwqqVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAylfmtlgafGVI 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  215 LFLALNHSSTTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYM 294
Cdd:PRK05777 343 SLLRRKGGEAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYL 422


                 ...
gi 23344006  295 RII 297
Cdd:PRK05777 423 RVI 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-197 3.25e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 79.29  E-value: 3.25e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   13 ILLGTSLTLFSSHWLTAWMGLEINTLAI-IPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWTLSQISD 91
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   92 QTSSTI----MTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSLNmkILITMALLSTILGGW 167
Cdd:MTH00199 186 ILTGDVgkilITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVLSIIYGAI 263

                        170       180       190
                 ....*....|....*....|....*....|
gi 23344006  168 GGLNQIHLRKILAYSSITHMGWMIIIILIN 197
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMGFILFGVAIG 293
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-297 3.63e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 73.06  E-value: 3.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006     4 YILLMLStsiLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTN 82
Cdd:TIGR01770 105 YILLLFA---LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLkRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    83 QWTLSQISDQTSST------------IMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIAPTSLMYQISPSL- 149
Cdd:TIGR01770 182 SLNFEDLLLFLSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIl 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   150 ------NMKILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLN----------LFTYITTTL 213
Cdd:TIGR01770 262 fgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlfyifiyalMSLGAFGVL 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   214 TLFLALNHSSTTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFY 293
Cdd:TIGR01770 342 SLLRSYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYY 421


                  ....
gi 23344006   294 MRII 297
Cdd:TIGR01770 422 LRVV 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 4-300 4.14e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 72.87  E-value: 4.14e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   4 YILLMLStsiLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQ 83
Cdd:COG0651 110 YPLFLLL---LAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGT 186

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  84 WTLSQISD----------QTSSTIMTLALAMKLGLAPFHFWVPK-----------LPQGIPLTSGM--ILLTWQKIAPTS 140
Cdd:COG0651 187 LNMADLAArlaeldpgllLAAFALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGAD 266

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 141 LMYQISPslnmkILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLnlftyitttLTLFLALN 220
Cdd:COG0651 267 PALFLGT-----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLA---------GALFHLLN 332

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 221 HS-----------------STTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMA 283
Cdd:COG0651 333 HAlakallflaagaieratGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLL 412

                       330
                ....*....|....*..
gi 23344006 284 MSTLLNLFFYMRIIYTT 300
Cdd:COG0651 413 LSSLLTLAYFVRIFGRA 429
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-192 3.20e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 70.66  E-value: 3.20e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   15 LGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRAT---------ESAIKYFLTQTTASMMLMFAIINNAWMT-NQW 84
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTgNEG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   85 TLSQISDQTSST-------------IMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILLTWQKIapTSLMYQISPSLNM 151
Cdd:MTH00198 279 MLGTILSATLETtnielrqgslgylFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 23344006  152 KILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMII 192
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 4-299 2.02e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 58.57  E-value: 2.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    4 YILLMLSTSILLGTSLT--LFSshwltAWMGLEINTLAIIPMMTYPNH-PRATESAIKYFLTQTTASMMLMFAI------ 74
Cdd:PRK08376 124 YTLILLLELGMLGMAITgdLFN-----FFVFLEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGIallygq 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   75 ---INNAWMTNQWTLS-QISDQTSSTIMTLALAMKLGLAPFHFWVP----KLPQGIpltSGMILLTwqKIAPTSLMYQIS 146
Cdd:PRK08376 199 ygtLNMAYLAVKMSENpTVVAKIALALFIAGLAMKSGAVPVHMWLPdaypAAPSSI---SAMLLVI--KQAGLYALARVL 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  147 -----PSLNMK----ILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMII---IILINPTLTLLNLFTYITTTLT 214
Cdd:PRK08376 274 fsiygPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLglgVGLAALGDPAMASYGEIALAGG 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  215 LFLALNHS-----------------STTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNIT 277
Cdd:PRK08376 354 IYHIVNHAlykallfltagaviyetGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYESSALFNPIL 433

                        330       340
                 ....*....|....*....|..
gi 23344006  278 TATIMaMSTLLNLFFYMRIIYT 299
Cdd:PRK08376 434 GVIAM-IGSVLTLASFVKVFHT 454
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-333 1.38e-07

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 47.64  E-value: 1.38e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 23344006   291 FFYMRIIYTTTLTMFPSTNNSKLQWHHQQTKTTNIIPPLTIIS 333
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLS 43
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-192 1.11e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 50.08  E-value: 1.11e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  49 HPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWTLS-------QISDQTSSTIMT---LALAMKLGLAPFHFWVPKL 118
Cdd:COG1008 156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTFDiaelaaaPLPLTAQLLLFLaffIAFAVKVPMFPFHTWLPDA 235

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 119 PQGIPLTSGMIL---------------------LTWQKIAPtslmyqispslnmkILITMALLSTILGGWGGLNQIHLRK 177
Cdd:COG1008 236 HVEAPTAGSVLLagvllkmggygllrfalplfpEASAYFAP--------------LLAALGVIGIIYGALVALAQTDLKR 301

                       170
                ....*....|....*
gi 23344006 178 ILAYSSITHMGWMII 192
Cdd:COG1008 302 LIAYSSVSHMGFVLL 316
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
14-192 1.65e-06

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 49.70  E-value: 1.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   14 LLGTSLTLFSSHWLT---AWM--GLEINTLaiipMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWTLSQ 88
Cdd:PRK08168 110 LAAVHLLVLSDHLLVliaAWAaiSLALHRL----LCFYPDRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLSA 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   89 I-----------SDQTSSTIMTLALAMKLGLAPFHFWVPK-----------LPQGIPLTSGMILLtwqKIAPtslMYQIS 146
Cdd:PRK08168 186 LwahlaaqgaspSLQAAALLLVLAVILKTAQLPVHGWLIQvmeaptpvsalLHAGVVNLGGFVLI---RFAP---LLEQA 259

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 23344006  147 PSLNMkILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMII 192
Cdd:PRK08168 260 PPARW-LLVLVGLATAVLAGLVMLTRISIKVRLAWSTVAQMGFMLL 304
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-195 1.90e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 49.23  E-value: 1.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   51 RATESAIKYFLTQTTASMMLMFAI----------INNAWMTNQWTLSQISDQTSSTI----MTLALAMKLGLAPFHFWVP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGFswlyglsggeIELQEIVNGLINTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  117 KLPQGIPLTSGMILLTWQKIAPTSLMYQIS----PSLNMK---ILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALATRIFdipfYFSSNEwhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318


                 ....*.
gi 23344006  190 MIIIIL 195
Cdd:CHL00049 319 VIIGII 324
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 55-194 2.62e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 45.70  E-value: 2.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    55 SAIKYFLTQTTASMMLMFAIINNAWMT------NQWTLSQISDQTSSTIMT---LALAMKLGLAPFHFWVPK-----LPQ 120
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGggtfdlLELLNLPLPFGVQTWLFLaffIAFAVKVPLFPLHTWLPDahveaPTA 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   121 GIPLTSGMILltwqKIAPTSLM---YQISPSLN---MKILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIII 194
Cdd:TIGR01972 237 GSVILAGVLL----KMGTYGFLrfnLPLFPDASlyfAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGI 312
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 4-298 2.77e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 45.64  E-value: 2.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    4 YILLMLSTSILLGTSLT--LFsshwlTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWMT 81
Cdd:PRK08375 109 YALFLLLLAGLLGALLTadLF-----NLFVFLEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVT 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   82 NQWTLSQISD--------QTSSTIMTLALAMKLGLAPFHFWVPK-LPQGIPLTSGMILLTWQKIAPTSLM---------- 142
Cdd:PRK08375 184 GTLNMADLAGalaenptvVTAFGFVLLALALKAAVFPLHTWLPRaYPAAPPVVTALLSGLVTKVAVYALIriyftvfggd 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  143 YQISPSLNMkILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMII-IILINPT------LTLLNLFTYITTTLTL 215
Cdd:PRK08375 264 FRFALGLGW-LLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLgLALLTPLalaaglLHLLHHALMKGALFLA 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  216 F-LALNHSSTTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYM 294
Cdd:PRK08375 343 AgAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFL 422


                 ....
gi 23344006  295 RIIY 298
Cdd:PRK08375 423 RIWY 426
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 59-202 3.43e-05

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 45.30  E-value: 3.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   59 YFLTQTTASMMLMFAIINNAWMTNQWTLSQ----ISDQTSSTI---MTLALAMKLGLAPFHFWVPKLPQGIPLTSGM--- 128
Cdd:MTH00226 190 YTLIGSVLMLLCLFSLYNIHGTTDYLTLAScshvVSEQTQKWIflgIFLAMAVKIPIFPFHIWLPKAHVEAPVAGSVlla 269

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 23344006  129 -ILLTWQKIAPTSLMYQISPSLNMKI---LITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTL 202
Cdd:MTH00226 270 gILLKLGGYGLVRLSWPILPLGAQNLapaVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGL 347
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-202 1.31e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 43.59  E-value: 1.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   13 ILLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTA------SMMLMFAIINNAWMTNQWTL 86
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   87 SQISDQT----------SSTIMTLALAMKLGLAPFHFWVP----KLPQ-------GIPLTSGM--ILLTWQKIAPTSLMY 143
Cdd:PRK08676 191 TELAAHAsllspsvlgaSFLFIFIGFLAKSGLVPFHTWLPaayaKAPSvvsallsGTVLNIGIygILRLSALLRQSGAAE 270

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 23344006  144 QISPslnmkILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTL 202
Cdd:PRK08676 271 QFSN-----VLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLAL 324
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 46-192 1.49e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 43.60  E-value: 1.49e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  46 YPNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWTLSQI----SDQTSSTIMTLALAM-------KLGLAPFHFW 114
Cdd:COG1009 154 WYEKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELlaaaPTILSSPLLTLILLLlllgafgKSAQFPLHFW 233

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006 115 vpkLPQ--------------------GIPLtsgmilltwqkIAPTSLMYQISPSLNMkILITMALLSTILGGWGGLNQIH 174
Cdd:COG1009 234 ---LPDamegptpvsallhaatmvkaGVYL-----------LARLSPLFALSPVWLT-VVAIIGAITALFAALIALAQTD 298

                       170
                ....*....|....*...
gi 23344006 175 LRKILAYSSITHMGWMII 192
Cdd:COG1009 299 IKRVLAYSTVSQLGYMFL 316
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 44-299 2.38e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 42.65  E-value: 2.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   44 MTYPNHPRATESAIKYFLTQTTASMMLMFA--IINNAWMT-NQWTLSQISDQTSSTIMT-------LALAMKLGLA---- 109
Cdd:PRK12667 154 AYYRDRGDAVEAAIKYALIGAVGTTLYFLAlaFLYATFGTlNMADLSAKIRGLSFPLTGglagnppLALGVALALAlwaf 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  110 -------PFHFWVPKLPQGIP-----LTSGMI-------------LLTWQKIAPTSLMYQISPslnmkILITMALLSTIL 164
Cdd:PRK12667 234 tikaaifPNHFWLPDAHPAAPspvsaMLSGLVvnvgayaiirflyTIFGISPSLIDFRAALSP-----ILIILGAVSAII 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  165 GGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYI--------TTTLTLFLALNHSSTTKIKSLANLWNK 236
Cdd:PRK12667 309 GALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksLLFLASGVFIHAAGTRDIDELAGLGRK 388

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 23344006  237 STPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLFFYMRIIYT 299
Cdd:PRK12667 389 MPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 6-307 4.45e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 41.91  E-value: 4.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    6 LLMLSTSILLGTsltLFSSHWLTAWMGLEINTLAIIpMMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWT 85
Cdd:PRK08668 103 FALMSLAGVLGV---FLANDLLTLYIFWEIMTFSSF-MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFD 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   86 LSQISD---QTSSTIMTLALAM--------KLGLAPFHFWVPKLPQGIPLT-----SG-------------MILLTWQKI 136
Cdd:PRK08668 179 FADISQgliNDTSTGFALIVFLfllafgvaKAGIFPLHVWAPDAYSEAPQSfsavlSGqlsklgaygfllvLYVLPGTKL 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  137 APTSLMYQISPSLNMkILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTL-------LNLFTYI 209
Cdd:PRK08668 259 FSEFGTYRGVPLFNY-ILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFagglfhvFNHALFK 337

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  210 TTTLTLFLALNH-SSTTKIKSLANLWNKsTPMTIVI-IITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTL 287
Cdd:PRK08668 338 GLFFLIFAAVIYrTGTTKISEMGGLIEK-MPFTFAMyLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSI 416

                        330       340
                 ....*....|....*....|
gi 23344006  288 LNLFFYMRIIYTTTLTMFPS 307
Cdd:PRK08668 417 GSFLYVFRPLAGVFLGQLPS 436
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-188 1.72e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 40.04  E-value: 1.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  100 LALAMKLGLAPFHFWVPKLPQGIPLTSGMIL--------------LTWqKIAPTSLMYqISPslnmkILITMALLSTILG 165
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQAHVEAPVAGSVILagvllklggygfirFSW-PLLPEASEY-FSP-----LIQTLSLLAIIYG 286

                         90       100
                 ....*....|....*....|...
gi 23344006  166 GWGGLNQIHLRKILAYSSITHMG 188
Cdd:MTH00217 287 SLTTCRQVDLKRIIAYSSVAHMG 309
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 4-297 1.84e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 40.10  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    4 YILLMLSTSILLGTsltLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMFAI--------- 74
Cdd:PRK12662 113 YSAFLLCLGGLLGI---LVSNDVFNIYVFLEISSISSYVLVAMGRDKKALVAAFEYLIIGTIGATFYLIGIgflyaitgt 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   75 --INNAWMTNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIP----------LTSGMILL---TWQKIAPT 139
Cdd:PRK12662 190 lnMGDMFLIIQDLPTNRAIQIGVLFIMVGLFIKAALFPFHKWLIQAYSEAPsfisvffsgtSTKVMIYLiirIVYDVFKA 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  140 SLMYQISPSLNMkiLITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLL--------NLFTYITT 211
Cdd:PRK12662 270 NFVFTTLPFNNV--FMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAaavayivnHSIVKSAL 347

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  212 TLTLFLALNHSSTTKIKSLANLWNKSTPMTIVIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAMSTLLNLF 291
Cdd:PRK12662 348 FMVSGSISYHFGTTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVI 427


                 ....*.
gi 23344006  292 FYMRII 297
Cdd:PRK12662 428 YVWKIV 433
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 30-190 2.10e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 39.91  E-value: 2.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   30 WMGLEINTLAIIPMMTYPNHPRATESAIKYFL------TQTTASMMLMFA----IINNAWMTNQWT-LSQISDQTSSTIM 98
Cdd:PRK06458 134 WVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYAnaatVMGDGEMAILWTeLLKHASLLDPTLM 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   99 TLALAM-------KLGLAPFHFWVPKLPQGIP-----LTSGMIL-------LTWQKIAPTSLMYQISPSLnmkiLITMAL 159
Cdd:PRK06458 214 KLAFVFlligfgtKVGLFPMHAWLPDAHSEAPspvsaLLSGVLLnvalyavLRYYILIDAAIGSDFPGRL----LLIFGL 289

                        170       180       190
                 ....*....|....*....|....*....|.
gi 23344006  160 LSTILGGWGGLNQIHLRKILAYSSITHMGWM 190
Cdd:PRK06458 290 LSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 43-196 4.23e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 38.94  E-value: 4.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   43 MMTYPNHPRATESAIKYFLTQTTASMMLMFAIINNAWMTNQWTLSqiSDQTSSTIMTL-------ALAMKLGLAPFHFWV 115
Cdd:PRK08667 151 VMNDYQEEETQRAGIFYFVMTQLSTVFLMLGIIVLFIQTGSFELS--PLGASAGILSLvflllflGFGIKAGIIPFHKWL 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  116 PKLPQGIP-----LTSGMILLTWQKIAPTSLMYQISPSLNMKILI-TMALLSTILGGWGGLNQIHLRKILAYSSITHMGw 189
Cdd:PRK08667 229 PYAHPASPsnvsaLMSGVMLKVAVYGLVRFLMDVLSPELWWGVLIlLAGSISALLGVIYALKEHDLKGLLAYSSIENIG- 307


                 ....*..
gi 23344006  190 mIIIILI 196
Cdd:PRK08667 308 -IILMGI 313
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 61-194 4.36e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 39.14  E-value: 4.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   61 LTQTTA---SMMLMFAIINNAwmTNQWTLSQI-SDQTSSTIMTLALAM-------KLGLAPFHFWVPklpqgipltSGMI 129
Cdd:PRK12644 163 LLVTTAgglAMLVGIIILGQA--AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLP---------GAMA 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  130 lltwqkiAPTS----------------LMYQISPSLN-----MKILITMALLSTILGGWGGLNQIHLRKILAYSSITHMG 188
Cdd:PRK12644 232 -------APTPvsaylhaaamvkagiyLVARLAPGFAdvpvwRPTVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLG 304


                 ....*.
gi 23344006  189 WMIIII 194
Cdd:PRK12644 305 FLTVLV 310
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-298 5.20e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 38.64  E-value: 5.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006    2 SPYILLMLSTSILLGTSLTlFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQTTASMMLMF---AIINNA 78
Cdd:PRK06589 115 SSRFLFFFNLTILIGVLIA-LSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLpavILIYTK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   79 WMTNQWTLSQISDQTSSTI---MTLALAMKLGLAPFHFWVPK-----------LPQGIPLTSGMILLTWQKIAPTSLMYQ 144
Cdd:PRK06589 194 TGNLDFVSGGLFSKNQSIIlllMFIYGIAKTAIFPVHSWLPAamvahypvsalLHAVIVVKTGLFCIYKILLYIFGLSYL 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  145 ISPSLNMKILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTLTLLNLFTYITTTLTLFLALNHS-- 222
Cdd:PRK06589 274 QRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSmg 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006  223 ---STTKIKSLANLWNKSTPMTI---VIIITLLSLGGLPPLTGFSPKWLILQELITHNNITTATIMAM----STLLNLFF 292
Cdd:PRK06589 354 siySLKKEDQVDKLHGTSKSFPLisfIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLvviaSSILSALY 433


                 ....*.
gi 23344006  293 YMRIIY 298
Cdd:PRK06589 434 LLKILS 439
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 57-200 6.07e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 38.42  E-value: 6.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   57 IKYFLTQTTASMMLMFAIINNAWMTNQWTLsqisdqtsstIMTLALAMKLGLAPFHFWVPKLPQGIPLTSGMILL----- 131
Cdd:MTH00205 160 FFLNSLNFSLSMFFNFPLNFSDFYLFLYWI----------FLMLAFLVKLPMYFVHLWLPKAHVEAPVSGSMILAgvllk 229

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 23344006  132 --TWQKIAPTSLMYQISpSLNMKILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILINPTL 200
Cdd:MTH00205 230 lgGYGLIRITSMLYKLN-SNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSW 299
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 55-197 6.38e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 38.28  E-value: 6.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23344006   55 SAIKYFLTQT-TASMMLMFAII--------NNAWMTNQWTLSQISDQTSSTIMTLALAMKLGLAPFHFWVPKLPQGIPLT 125
Cdd:MTH00150 106 QAGMYMMLYTvGASLPLLLVILwmsssygsSFMLLISSLRKLLSSMGLWGLLVFLAFLVKLPMYPFHLWLPKAHVEAPVA 185

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 23344006  126 SGMIL------LTWQKIAPTSLMYQISPSLNMKILITMALLSTILGGWGGLNQIHLRKILAYSSITHMGWMIIIILIN 197
Cdd:MTH00150 186 GSMILagillkLGGYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSN 263
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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