NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|268552741|ref|XP_002634353|]
View 

Protein CBG17703 [Caenorhabditis briggsae]

Protein Classification

zf-C3HC domain-containing protein( domain architecture ID 10546421)

zf-C3HC domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
zf-C3HC pfam07967
C3HC zinc finger-like; This zinc-finger like domain is distributed throughout the eukaryotic ...
 48-178 3.86e-39

C3HC zinc finger-like; This zinc-finger like domain is distributed throughout the eukaryotic kingdom in NIPA (Nuclear interacting partner of ALK) proteins. NIPA is implicate to perform some sort of antiapoptotic role in nucleophosmin-anaplastic lymphoma kinase (ALK) mediated signaling events. The domain is often repeated, with the second domain usually containing a large insert (approximately 90 residues) after the first three cysteine residues. The Schizosaccharomyces pombe the protein containing this domain is involved in mRNA export from the nucleus.


:

Pssm-ID: 429759  Cd Length: 132  Bit Score: 134.04  E-value: 3.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268552741   48 RDVEAYKKIIKTYKAPTWFG--CAVSPRDLADYGWECVKKDCVKCVECEELLCTSLPNICKVSFNVYNSRLQEIHDQLSS 125
Cdd:pfam07967   2 WSREDFLRRLKTFKALTWTGkpSALSPLACAKRGWVCVDKDMLKCESCGAYLCVSKDNIVELDFQLYNKLIEEYAKQLVT 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 268552741  126 AHRTTCKLRTGAPPiRFTEPTSkeIMSGiQSRLSDSKSIEDDDFV--VHIPSDVN 178
Cdd:pfam07967  82 GHEENCPWRNNGCP-ESYERLP--LAAP-DTLLSDLKKRYDGLLQrfDQLPSLVN 132
 
Name Accession Description Interval E-value
zf-C3HC pfam07967
C3HC zinc finger-like; This zinc-finger like domain is distributed throughout the eukaryotic ...
 48-178 3.86e-39

C3HC zinc finger-like; This zinc-finger like domain is distributed throughout the eukaryotic kingdom in NIPA (Nuclear interacting partner of ALK) proteins. NIPA is implicate to perform some sort of antiapoptotic role in nucleophosmin-anaplastic lymphoma kinase (ALK) mediated signaling events. The domain is often repeated, with the second domain usually containing a large insert (approximately 90 residues) after the first three cysteine residues. The Schizosaccharomyces pombe the protein containing this domain is involved in mRNA export from the nucleus.


Pssm-ID: 429759  Cd Length: 132  Bit Score: 134.04  E-value: 3.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268552741   48 RDVEAYKKIIKTYKAPTWFG--CAVSPRDLADYGWECVKKDCVKCVECEELLCTSLPNICKVSFNVYNSRLQEIHDQLSS 125
Cdd:pfam07967   2 WSREDFLRRLKTFKALTWTGkpSALSPLACAKRGWVCVDKDMLKCESCGAYLCVSKDNIVELDFQLYNKLIEEYAKQLVT 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 268552741  126 AHRTTCKLRTGAPPiRFTEPTSkeIMSGiQSRLSDSKSIEDDDFV--VHIPSDVN 178
Cdd:pfam07967  82 GHEENCPWRNNGCP-ESYERLP--LAAP-DTLLSDLKKRYDGLLQrfDQLPSLVN 132
 
Name Accession Description Interval E-value
zf-C3HC pfam07967
C3HC zinc finger-like; This zinc-finger like domain is distributed throughout the eukaryotic ...
 48-178 3.86e-39

C3HC zinc finger-like; This zinc-finger like domain is distributed throughout the eukaryotic kingdom in NIPA (Nuclear interacting partner of ALK) proteins. NIPA is implicate to perform some sort of antiapoptotic role in nucleophosmin-anaplastic lymphoma kinase (ALK) mediated signaling events. The domain is often repeated, with the second domain usually containing a large insert (approximately 90 residues) after the first three cysteine residues. The Schizosaccharomyces pombe the protein containing this domain is involved in mRNA export from the nucleus.


Pssm-ID: 429759  Cd Length: 132  Bit Score: 134.04  E-value: 3.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268552741   48 RDVEAYKKIIKTYKAPTWFG--CAVSPRDLADYGWECVKKDCVKCVECEELLCTSLPNICKVSFNVYNSRLQEIHDQLSS 125
Cdd:pfam07967   2 WSREDFLRRLKTFKALTWTGkpSALSPLACAKRGWVCVDKDMLKCESCGAYLCVSKDNIVELDFQLYNKLIEEYAKQLVT 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 268552741  126 AHRTTCKLRTGAPPiRFTEPTSkeIMSGiQSRLSDSKSIEDDDFV--VHIPSDVN 178
Cdd:pfam07967  82 GHEENCPWRNNGCP-ESYERLP--LAAP-DTLLSDLKKRYDGLLQrfDQLPSLVN 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH