NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|27807083|ref|NP_777024|]
View 

excitatory amino acid transporter 3 [Bos taurus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
16-468 6.24e-119

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 355.96  E-value: 6.24e-119
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  16 RNNWLLLSTVVAVVLGIVIGVLVREYSKLsnlekfYFSFPGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGKIGLRA 94
Cdd:COG1301   1 FKLSLTLQILIALVLGILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  95 VVYYFCTTLIAVILGIVLVVSIKPGVTqkVNEIDRTGNTPEVSTVDAMLDLIRNMFPENLVQAcfqqykttreevelsee 174
Cdd:COG1301  75 LLYFLVTTTIALVIGLVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA----------------- 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 175 pgtnsteatvtaiMTTAisknktkeykvvgmysdgiNVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQII 254
Cdd:COG1301 136 -------------FAEG-------------------NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWV 183

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 255 MCYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGMAQALLTALMISSSS 334
Cdd:COG1301 184 MKLAPIGVFALIAATVAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSE 262

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 335 ATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQP 414
Cdd:COG1301 263 ATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGA 342

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|....
gi 27807083 415 GLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 468
Cdd:COG1301 343 GLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
16-468 6.24e-119

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 355.96  E-value: 6.24e-119
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  16 RNNWLLLSTVVAVVLGIVIGVLVREYSKLsnlekfYFSFPGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGKIGLRA 94
Cdd:COG1301   1 FKLSLTLQILIALVLGILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  95 VVYYFCTTLIAVILGIVLVVSIKPGVTqkVNEIDRTGNTPEVSTVDAMLDLIRNMFPENLVQAcfqqykttreevelsee 174
Cdd:COG1301  75 LLYFLVTTTIALVIGLVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA----------------- 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 175 pgtnsteatvtaiMTTAisknktkeykvvgmysdgiNVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQII 254
Cdd:COG1301 136 -------------FAEG-------------------NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWV 183

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 255 MCYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGMAQALLTALMISSSS 334
Cdd:COG1301 184 MKLAPIGVFALIAATVAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSE 262

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 335 ATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQP 414
Cdd:COG1301 263 ATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGA 342

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|....
gi 27807083 415 GLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 468
Cdd:COG1301 343 GLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
20-465 2.19e-115

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 346.05  E-value: 2.19e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083    20 LLLSTVVAVVLGIVIGVLVREYSKlsnlekfYFSFPGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGKIGLRAVVYY 98
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA-------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083    99 FCTTLIAVILGIVLVVSIKPGVTQkvNEIDRTGNTPEVSTVDAMLDLIRNMFPENLVQACFQQykttreevelseepgtn 178
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGL--ALIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   179 steatvtaimttaisknktkeykvvgmysdgiNVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQIIMCYM 258
Cdd:pfam00375 135 --------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLA 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   259 PIGILFLIAGKIIEvEDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGMAQALLTALMISSSSATLP 338
Cdd:pfam00375 183 PIGVFALIANTVGT-YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLP 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   339 VTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLVT 418
Cdd:pfam00375 262 VTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVA 341

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 27807083   419 MVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKL 465
Cdd:pfam00375 342 LGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 25-464 5.60e-40

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 150.30  E-value: 5.60e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   25 VVAVVLGIVIGVLVREYSKLSN-LEKFYFSFPGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGKIGLRAVVYYFCTT 102
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDwLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  103 LIAVILGIVLVVSIKPGVTqkvneIDRTgntpEVSTVDamldlirnmfpenlvqacFQQYKTTREEVElseePGTNSTEA 182
Cdd:PRK11283  93 TVAIILGITLANVFQPGAG-----IDMS----QLATVD------------------ISKYQSTTEEVQ----SHSHGLMG 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  183 TVTAIMTTAISKNKTKEykvvgmysdgiNVLGLIVFCLVLGIVIGRKWEK-GQILVDFFNALSDATMKIVQIIMCYMPIG 261
Cdd:PRK11283 142 TILSLIPTNIFASMAKG-----------EMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVG 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  262 ILFLIAgkiIEVEDWEIFRKLGLYMATVLSGLAI--HSIVILPLIYFIIvRKNPFQFAMGMAQALLTALMISSSSATLPv 339
Cdd:PRK11283 211 VFALIA---VTVANFGFASLWPLAKLVLLVYFAIlfFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLP- 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  340 tfRCAE--EKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLV 417
Cdd:PRK11283 286 --RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFV 363

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 27807083  418 TMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 464
Cdd:PRK11283 364 VLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
16-468 6.24e-119

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 355.96  E-value: 6.24e-119
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  16 RNNWLLLSTVVAVVLGIVIGVLVREYSKLsnlekfYFSFPGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGKIGLRA 94
Cdd:COG1301   1 FKLSLTLQILIALVLGILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  95 VVYYFCTTLIAVILGIVLVVSIKPGVTqkVNEIDRTGNTPEVSTVDAMLDLIRNMFPENLVQAcfqqykttreevelsee 174
Cdd:COG1301  75 LLYFLVTTTIALVIGLVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA----------------- 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 175 pgtnsteatvtaiMTTAisknktkeykvvgmysdgiNVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQII 254
Cdd:COG1301 136 -------------FAEG-------------------NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWV 183

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 255 MCYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGMAQALLTALMISSSS 334
Cdd:COG1301 184 MKLAPIGVFALIAATVAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSE 262

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 335 ATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQP 414
Cdd:COG1301 263 ATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGA 342

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|....
gi 27807083 415 GLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 468
Cdd:COG1301 343 GLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
20-465 2.19e-115

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 346.05  E-value: 2.19e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083    20 LLLSTVVAVVLGIVIGVLVREYSKlsnlekfYFSFPGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGKIGLRAVVYY 98
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA-------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083    99 FCTTLIAVILGIVLVVSIKPGVTQkvNEIDRTGNTPEVSTVDAMLDLIRNMFPENLVQACFQQykttreevelseepgtn 178
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGL--ALIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   179 steatvtaimttaisknktkeykvvgmysdgiNVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQIIMCYM 258
Cdd:pfam00375 135 --------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLA 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   259 PIGILFLIAGKIIEvEDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGMAQALLTALMISSSSATLP 338
Cdd:pfam00375 183 PIGVFALIANTVGT-YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLP 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   339 VTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLVT 418
Cdd:pfam00375 262 VTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVA 341

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 27807083   419 MVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKL 465
Cdd:pfam00375 342 LGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 25-464 5.60e-40

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 150.30  E-value: 5.60e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   25 VVAVVLGIVIGVLVREYSKLSN-LEKFYFSFPGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGKIGLRAVVYYFCTT 102
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDwLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  103 LIAVILGIVLVVSIKPGVTqkvneIDRTgntpEVSTVDamldlirnmfpenlvqacFQQYKTTREEVElseePGTNSTEA 182
Cdd:PRK11283  93 TVAIILGITLANVFQPGAG-----IDMS----QLATVD------------------ISKYQSTTEEVQ----SHSHGLMG 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  183 TVTAIMTTAISKNKTKEykvvgmysdgiNVLGLIVFCLVLGIVIGRKWEK-GQILVDFFNALSDATMKIVQIIMCYMPIG 261
Cdd:PRK11283 142 TILSLIPTNIFASMAKG-----------EMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVG 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  262 ILFLIAgkiIEVEDWEIFRKLGLYMATVLSGLAI--HSIVILPLIYFIIvRKNPFQFAMGMAQALLTALMISSSSATLPv 339
Cdd:PRK11283 211 VFALIA---VTVANFGFASLWPLAKLVLLVYFAIlfFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLP- 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  340 tfRCAE--EKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLV 417
Cdd:PRK11283 286 --RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFV 363

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 27807083  418 TMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 464
Cdd:PRK11283 364 VLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 12-464 1.75e-37

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 143.12  E-value: 1.75e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   12 KRFLRNnwLLLSTVVAVVLGIVIGVLVREY-SKLSNLekfyfsfpGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGK 89
Cdd:PRK01663   3 KPLYKS--LYFQVLVAIIIGILLGHFYPELgAQMKPL--------GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   90 IGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVNeidrtgntpeVSTVDAmldlirnmfpenlvqACFQQYKTtreev 169
Cdd:PRK01663  73 VGGKALLYFEIVSTIALIIGLIVVNVVQPGAGMNID----------PATLDA---------------KAVAQYAA----- 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  170 elseepgtNSTEATVTAIMTTAISKNktkeykVVGMYSDGiNVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMK 249
Cdd:PRK01663 123 --------QAHEQGTVDFLMDIIPTT------VVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFG 187

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  250 IVQIIMCYMPIGILFLIA--------GKIIevedweifrKLGLYMATVLSGLAIHSIVILPLIY----FIIvrknpFQFA 317
Cdd:PRK01663 188 IVNMIMKLAPIGAFGAMAftigkygvGSLV---------QLGQLIGCFYITCILFVFVVLGAIArltgFSI-----FKFI 253

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  318 MGMAQALLTALMISSSSATLPVTFRcAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITI 397
Cdd:PRK01663 254 RYIKEELLIVLGTSSSESALPRMME-KMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITL 332

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 27807083  398 SVTATAASIGAAGVPQPGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 464
Cdd:PRK01663 333 LAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAK 400
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 12-462 3.10e-34

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 133.64  E-value: 3.10e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   12 KRFLRNnwLLLSTVVAVVLGIVIGVLVREYS-KLSNLekfyfsfpGEILMRMLKLVILPLIVSSMITGVATL-DSNVSGK 89
Cdd:PRK13027   2 KKFLRS--LFGQVVIALVLGVALGAFFPHFAeSLKPL--------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGR 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083   90 IGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVNeidrtgntpevstvdamldlirnmfPENLVQACFQQYKTTREEV 169
Cdd:PRK13027  72 VGLKAVIYFEVMTTIALVIGLVLAYLTGPGVGMNID-------------------------LRSLDAASLAGYAKNAQSL 126

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  170 ElseepgtNSTEATVTAIMTTAisknktkeykvVGMYSDGiNVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMK 249
Cdd:PRK13027 127 K-------GTAGFLLKLIPTTA-----------VDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFR 187

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  250 IVQIIMCYMPIGILFLIAgkiIEVEDWEI--FRKLGLYMATVLSGLAIHSIVILPLIyfiiVRKNPF---QFAMGMAQAL 324
Cdd:PRK13027 188 IMGFIIKLAPLGVLGAIA---FTTGKYGVgsLKQLGMLVAVFYLTCFVFVVVVLGAV----MRLAGFsvfKLIRYLREEL 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  325 LTALMISSSSATLPVTFRcAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLSVGQIITISVTATAA 404
Cdd:PRK13027 261 LIVLGTASSDAVLPQVMR-KLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVT 339

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 27807083  405 SIGAAGVPQPGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIV 462
Cdd:PRK13027 340 SKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 238-411 2.97e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 68.35  E-value: 2.97e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  238 DFFNALSDATMKIVQIIMCYMPIGILFLIAGKIIEvEDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFA 317
Cdd:PRK13628 170 NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAE-TGFSALAGYAQLLAVLVGCMLFVALVVNPLIVFWKIRRNPYPLV 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  318 MG-MAQALLTALMISSSSATLPVTFRCAeEKNRVDKRITRFVLPVGATINMDGTALYEAV---AAVfiaqlNDLDLSV-- 391
Cdd:PRK13628 249 FTcLRESGVTAFFTRSSAANIPVNMALC-EKLGLDEDTYSVSIPLGATINMAGAAITITVltlAAV-----HTLGIPVdl 322

                        170       180
                 ....*....|....*....|
gi 27807083  392 GQIITISVTATAASIGAAGV 411
Cdd:PRK13628 323 PTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
238-412 8.50e-12

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 67.12  E-value: 8.50e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 238 DFFNALSDATMKIVQIIMCYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFA 317
Cdd:COG3633 169 TVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATT-GFSALLGYAHLLAVLVGCMLFVALVVNPLIVFLKIRRNPYPLV 247

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083 318 -MGMAQALLTALMISSSSATLPVTFRCAEEKNrVDKRITRFVLPVGATINMDGTALYEAV---AAVfiaqlNDLDLSV-- 391
Cdd:COG3633 248 fTCLRESGITAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVltlAAV-----HTLGIEVdl 321

                       170       180
                ....*....|....*....|.
gi 27807083 392 GQIITISVTATAASIGAAGVP 412
Cdd:COG3633 322 PTALLLSVVAAVSACGASGVA 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 211-469 1.66e-10

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 62.38  E-value: 1.66e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  211 NVLGLIVFCLVLGIVIGRKWEKGQilvDFFNALSDATMKIVQIIMCYMPIGILFLIAgKIIEVEDWEIFRKLGLYMATVL 290
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLANYGILLVLLV 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  291 SGLAIHSIVILPLIYFIIVRKNPFQFAMG-MAQALLTALMISSSSATLPVTFRCAEEKNrVDKRITRFVLPVGATINMDG 369
Cdd:PRK14695 136 TTMLFVAPVVNPLIAFFFMRRNPYPLVWNcLRVSGVTAFFTRSSATNIPVNMKLCHDLG-LNPDTYSVSIPLGSTINMAG 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27807083  370 TALYEAVAAVFIAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLVTMVIVLSAVGLPAEDVTLIIAVDWLL----DR 445
Cdd:PRK14695 215 VAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDS 294

                        250       260
                 ....*....|....*....|....
gi 27807083  446 FRTMVNVLGDAFGTGIVEKLSKKE 469
Cdd:PRK14695 295 CETALNSSTDVLFTAVAEYAATRK 318
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH