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Conserved domains on  [gi|2780914]
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Chain A, CYTOCHROME C3

Protein Classification

cytochrome c3 family protein( domain architecture ID 11128184)

cytochrome c3 (class III cytochrome c) family protein similar to Desulfovibrio tetraheme cytochromes c3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cytochrom_CIII pfam02085
Class III cytochrome C family;
1-106 3.73e-23

Class III cytochrome C family;


:

Pssm-ID: 396592  Cd Length: 103  Bit Score: 85.70  E-value: 3.73e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2780914      1 APKAPADGLKMeATKQPVVFNHSTHKSVKCGDCHHPVNGKEDYRKCGTAGCHDSMDKKdKSAKGYYHVMHDKNTkFKSCV 80
Cdd:pfam02085   5 VIDAPADAKPM-PTKKPVVFNHKAHASVDCATCHHKVDGGGKIAKCSTAGCHATEDDK-KDEKSLYKAMHSRKA-PKSCV 81

                          90       100
                  ....*....|....*....|....*.
gi 2780914     81 GCHVEVAGADaaKKKDLTGCkkSKCH 106
Cdd:pfam02085  82 GCHKKMKKEK--KCKGPTGC--AGCH 103
 
Name Accession Description Interval E-value
Cytochrom_CIII pfam02085
Class III cytochrome C family;
1-106 3.73e-23

Class III cytochrome C family;


Pssm-ID: 396592  Cd Length: 103  Bit Score: 85.70  E-value: 3.73e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2780914      1 APKAPADGLKMeATKQPVVFNHSTHKSVKCGDCHHPVNGKEDYRKCGTAGCHDSMDKKdKSAKGYYHVMHDKNTkFKSCV 80
Cdd:pfam02085   5 VIDAPADAKPM-PTKKPVVFNHKAHASVDCATCHHKVDGGGKIAKCSTAGCHATEDDK-KDEKSLYKAMHSRKA-PKSCV 81

                          90       100
                  ....*....|....*....|....*.
gi 2780914     81 GCHVEVAGADaaKKKDLTGCkkSKCH 106
Cdd:pfam02085  82 GCHKKMKKEK--KCKGPTGC--AGCH 103
Cytochrom_C3 cd08168
Heme-binding domain of the class III cytochrome C family and related proteins; This alignment ...
 15-107 1.32e-08

Heme-binding domain of the class III cytochrome C family and related proteins; This alignment models heme binding core motifs as encountered in the cytochrome C3 family and related proteins. Cytochrome C3 is a tetraheme protein found in sulfate-reducing bacteria which use either thiosulfate or sulfate as the ultimate electron acceptors. C3 is an integral part of a complex electron transfer chain. The model also contains triheme cytochromes C7 which function in electron transfer during Fe(III) respiration by Geobacter sulfurreducens (PpcA, PpcB, PpcC, PpcD, and PpcE) and four repeated core motifs as found in the 16-heme cytochrome C HmcA of Desulfovibrio vulgaris Hildenborough which plays a role in electron transfer through the membrane following periplasmic oxidation of hydrogen (resulting in sulfate reduction in the cytoplasm).


Pssm-ID: 173979 [Multi-domain]  Cd Length: 85  Bit Score: 48.00  E-value: 1.32e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2780914   15 KQPVVFNHSTHKSV---KCGDCHHPV-NGKEDYRKCGTAGCHDSMDKKDKSakGYYHVMHdkntkfKSCVGCHVEVAGAD 90
Cdd:cd08168   1 KGPVPFPHKKHAEAlgiDCRTCHHKYeGGKGEPQKCAECHSHDGTDDPDFV--SLKDAFH------NSCIGCHKEMAKAG 72

                        90
                ....*....|....*..
gi 2780914   91 aaKKKDLTGCKksKCHE 107
Cdd:cd08168  73 --KKTGPVGCA--GCHK 85
 
Name Accession Description Interval E-value
Cytochrom_CIII pfam02085
Class III cytochrome C family;
1-106 3.73e-23

Class III cytochrome C family;


Pssm-ID: 396592  Cd Length: 103  Bit Score: 85.70  E-value: 3.73e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2780914      1 APKAPADGLKMeATKQPVVFNHSTHKSVKCGDCHHPVNGKEDYRKCGTAGCHDSMDKKdKSAKGYYHVMHDKNTkFKSCV 80
Cdd:pfam02085   5 VIDAPADAKPM-PTKKPVVFNHKAHASVDCATCHHKVDGGGKIAKCSTAGCHATEDDK-KDEKSLYKAMHSRKA-PKSCV 81

                          90       100
                  ....*....|....*....|....*.
gi 2780914     81 GCHVEVAGADaaKKKDLTGCkkSKCH 106
Cdd:pfam02085  82 GCHKKMKKEK--KCKGPTGC--AGCH 103
Cytochrom_C3 cd08168
Heme-binding domain of the class III cytochrome C family and related proteins; This alignment ...
 15-107 1.32e-08

Heme-binding domain of the class III cytochrome C family and related proteins; This alignment models heme binding core motifs as encountered in the cytochrome C3 family and related proteins. Cytochrome C3 is a tetraheme protein found in sulfate-reducing bacteria which use either thiosulfate or sulfate as the ultimate electron acceptors. C3 is an integral part of a complex electron transfer chain. The model also contains triheme cytochromes C7 which function in electron transfer during Fe(III) respiration by Geobacter sulfurreducens (PpcA, PpcB, PpcC, PpcD, and PpcE) and four repeated core motifs as found in the 16-heme cytochrome C HmcA of Desulfovibrio vulgaris Hildenborough which plays a role in electron transfer through the membrane following periplasmic oxidation of hydrogen (resulting in sulfate reduction in the cytoplasm).


Pssm-ID: 173979 [Multi-domain]  Cd Length: 85  Bit Score: 48.00  E-value: 1.32e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2780914   15 KQPVVFNHSTHKSV---KCGDCHHPV-NGKEDYRKCGTAGCHDSMDKKDKSakGYYHVMHdkntkfKSCVGCHVEVAGAD 90
Cdd:cd08168   1 KGPVPFPHKKHAEAlgiDCRTCHHKYeGGKGEPQKCAECHSHDGTDDPDFV--SLKDAFH------NSCIGCHKEMAKAG 72

                        90
                ....*....|....*..
gi 2780914   91 aaKKKDLTGCKksKCHE 107
Cdd:cd08168  73 --KKTGPVGCA--GCHK 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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