|
Name |
Accession |
Description |
Interval |
E-value |
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
7-365 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 654.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 7 VNFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVP 86
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 87 LNLIGlkEERCADYLVTGTWSARAAKEAEKYG-KVNVIHPKL-DSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFI 164
Cdd:cd00611 81 LNLLG--DKGTADYVVTGAWSAKAAKEAKRYGgVVVIVAAKEeGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 165 PDTKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPC 244
Cdd:cd00611 159 PDTGGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 245 FSIYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNGFYSCPVDAACRSRMNIPFRIGKKEgdesLEKSFLDGAS 324
Cdd:cd00611 239 FAIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRLGKEE----LEKEFLKEAE 314
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 27881918 325 KLGMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLR 365
Cdd:cd00611 315 AAGMIGLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
8-367 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 614.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPL 87
Cdd:PRK05355 6 NFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQFAMVPM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLigLKEERCADYLVTGTWSARAAKEAEKYGKVNVIHPKLDS-YTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIPD 166
Cdd:PRK05355 86 NL--LGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASSEDDgFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFHELPD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 167 TKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCFS 246
Cdd:PRK05355 164 TGDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTPPTFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 247 IYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNgFYSCPVDAACRSRMNIPFRIgkkeGDESLEKSFLDGASKL 326
Cdd:PRK05355 244 IYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSSD-FYRNPVAPEDRSRMNVPFTL----ADEELDKKFLAEAKAA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 27881918 327 GMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNH 367
Cdd:PRK05355 319 GLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERRH 359
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
14-367 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 588.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 14 AKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPLNLigLK 93
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNL--LA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 94 EERCADYLVTGTWSARAAKEAEKYGKVNVI-HPKLDSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIPDTKGVIL 172
Cdd:TIGR01364 79 EGKVADYIVTGAWSKKAAKEAKKYGVVNVVaSGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 173 VSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCFSIYIMGL 252
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 253 VLEWIRNNGGADAMERLNKQKSALVYDIINRSNGFYSCPVDAACRSRMNIPFRIGKKEgdesLEKSFLDGASKLGMISLK 332
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGNEE----LEKRFLKEAEERGLVSLK 314
|
330 340 350
....*....|....*....|....*....|....*
gi 27881918 333 GHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNH 367
Cdd:TIGR01364 315 GHRSVGGMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
8-367 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 586.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPL 87
Cdd:COG1932 5 NFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMVPM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLIGlkEERCADYLVTGTWSARAAKEAEKYGKVNVIH-PKLDSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIPD 166
Cdd:COG1932 85 NLLR--GGKKADYLVTGEWSKKAIKEAKKYGEVNVVAsSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHELPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 167 TKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCFS 246
Cdd:COG1932 163 VGDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPPTFA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 247 IYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNgFYSCPVDAACRSRMNIPFRIgkkeGDESLEKSFLDGASKL 326
Cdd:COG1932 243 IYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASD-FYTNPVDPEDRSRMNVTFDL----ADEELDAAFLAEAKAA 317
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 27881918 327 GMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNH 367
Cdd:COG1932 318 GLVGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
8-356 |
4.57e-74 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 234.06 E-value: 4.57e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAQKELLDYSGTGISilEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSgQFSAVPL 87
Cdd:pfam00266 3 LDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGTTE-AINLVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLI-GLKEERCADYLVTGTWSAR-AAKEAEKYGKVNVIHPKLDSYTKI-PDSSTWSLNPSASYVYYCCNETVHGVeFNFI 164
Cdd:pfam00266 80 SLGrSLKPGDEIVITEMEHHANLvPWQELAKRTGARVRVLPLDEDGLLdLDELEKLITPKTKLVAITHVSNVTGT-IQPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 165 PD------TKGVILVSDMSSNFLSRPVDVSKFG--LIFAGAQKNVGCAGVTVVIVREDLIGKA--------LKECPiILD 228
Cdd:pfam00266 159 PEigklahQYGALVLVDAAQAIGHRPIDVQKLGvdFLAFSGHKLYGPTGIGVLYGRRDLLEKMppllggggMIETV-SLQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 229 YQVQAGNNSLYN--TPPCFSIYIMGLVLEWIrNNGGADAMERLNKQKSALVYDIInRSNGFYSCPVDAACRSRMNIPFRI 306
Cdd:pfam00266 238 ESTFADAPWKFEagTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERL-LSLPGIRLYGPERRASIISFNFKG 315
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 27881918 307 gkkeGDESLEKSFLDGA-------SKLGMISLKGHRSVGGIRASLYNAVTVEDVKIL 356
Cdd:pfam00266 316 ----VHPHDVATLLDESgiavrsgHHCAQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
7-365 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 654.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 7 VNFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVP 86
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 87 LNLIGlkEERCADYLVTGTWSARAAKEAEKYG-KVNVIHPKL-DSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFI 164
Cdd:cd00611 81 LNLLG--DKGTADYVVTGAWSAKAAKEAKRYGgVVVIVAAKEeGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 165 PDTKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPC 244
Cdd:cd00611 159 PDTGGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 245 FSIYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNGFYSCPVDAACRSRMNIPFRIGKKEgdesLEKSFLDGAS 324
Cdd:cd00611 239 FAIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRLGKEE----LEKEFLKEAE 314
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 27881918 325 KLGMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLR 365
Cdd:cd00611 315 AAGMIGLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
8-367 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 614.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPL 87
Cdd:PRK05355 6 NFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQFAMVPM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLigLKEERCADYLVTGTWSARAAKEAEKYGKVNVIHPKLDS-YTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIPD 166
Cdd:PRK05355 86 NL--LGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASSEDDgFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFHELPD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 167 TKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCFS 246
Cdd:PRK05355 164 TGDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTPPTFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 247 IYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNgFYSCPVDAACRSRMNIPFRIgkkeGDESLEKSFLDGASKL 326
Cdd:PRK05355 244 IYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSSD-FYRNPVAPEDRSRMNVPFTL----ADEELDKKFLAEAKAA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 27881918 327 GMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNH 367
Cdd:PRK05355 319 GLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERRH 359
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
14-367 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 588.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 14 AKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPLNLigLK 93
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNL--LA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 94 EERCADYLVTGTWSARAAKEAEKYGKVNVI-HPKLDSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIPDTKGVIL 172
Cdd:TIGR01364 79 EGKVADYIVTGAWSKKAAKEAKKYGVVNVVaSGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 173 VSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCFSIYIMGL 252
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 253 VLEWIRNNGGADAMERLNKQKSALVYDIINRSNGFYSCPVDAACRSRMNIPFRIGKKEgdesLEKSFLDGASKLGMISLK 332
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGNEE----LEKRFLKEAEERGLVSLK 314
|
330 340 350
....*....|....*....|....*....|....*
gi 27881918 333 GHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNH 367
Cdd:TIGR01364 315 GHRSVGGMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
8-367 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 586.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPL 87
Cdd:COG1932 5 NFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMVPM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLIGlkEERCADYLVTGTWSARAAKEAEKYGKVNVIH-PKLDSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIPD 166
Cdd:COG1932 85 NLLR--GGKKADYLVTGEWSKKAIKEAKKYGEVNVVAsSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHELPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 167 TKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCFS 246
Cdd:COG1932 163 VGDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPPTFA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 247 IYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNgFYSCPVDAACRSRMNIPFRIgkkeGDESLEKSFLDGASKL 326
Cdd:COG1932 243 IYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASD-FYTNPVDPEDRSRMNVTFDL----ADEELDAAFLAEAKAA 317
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 27881918 327 GMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNH 367
Cdd:COG1932 318 GLVGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PLN02452 |
PLN02452 |
phosphoserine transaminase |
8-368 |
0e+00 |
|
phosphoserine transaminase
Pssm-ID: 178071 Cd Length: 365 Bit Score: 526.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPL 87
Cdd:PLN02452 10 NFSAGPATLPANVLAKAQAELYNWEGSGMSVMEMSHRGKEFLSIIQKAEADLRELLDIPDNYEVLFLQGGASTQFAAIPL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLIglKEERCADYLVTGTWSARAAKEAEKYGKVNVIHP-KLDSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIPD 166
Cdd:PLN02452 90 NLC--KPGDKADFVVTGSWSKKAAKEAKKYCKTNVIASgKDEKYTKIPSVSEWELTPDAKFVHICANETIHGVEFKDYPD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 167 TKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCFS 246
Cdd:PLN02452 168 VGNVPLVADMSSNFLSKPVDVSKYGVIYAGAQKNVGPSGVTIVIIRKDLIGNARPITPGMLDYKIHAENDSLYNTPPCFG 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 247 IYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNGFYSCPVDAACRSRMNIPFRIGKKEgdesLEKSFLDGASKL 326
Cdd:PLN02452 248 IYMCGLVFEDLLAQGGLKAMEKRNIRKADLLYDAIDESNGFYVCPVEKSVRSLMNVPFTLGGSE----LEAEFVKEAAKA 323
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 27881918 327 GMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNHQ 368
Cdd:PLN02452 324 GMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA 365
|
|
| PRK12462 |
PRK12462 |
phosphoserine aminotransferase; Provisional |
7-367 |
1.37e-126 |
|
phosphoserine aminotransferase; Provisional
Pssm-ID: 183540 Cd Length: 364 Bit Score: 367.99 E-value: 1.37e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 7 VNFGAGPAKLPQSVLLQAQKELLDYSGTGISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVP 86
Cdd:PRK12462 6 LNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAEADLRDLLGIPDEYGVVFLQGGSSLQFSMIP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 87 LNLIgLKEERCADYLVTGTWSARAAKEAEKYGKVNVI-HPKLDSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFNFIP 165
Cdd:PRK12462 86 MNFS-RPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVwDGAASGYRTLPSLAELDWDARAPFRHYVSNETVEGLQFPDAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 166 DTKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGCAGVTVVIVREDLIGKALKECPIILDYQVQAGNNSLYNTPPCF 245
Cdd:PRK12462 165 GLPDSPLIADMSSDFMSRPFDVEAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNTPPVF 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 246 SIYIMGLVLEWIRNN-GGADAMERLNKQKSALVYDIINRSNGFYSCPVDAACRSRMNIPFRIGKKEgdesLEKSFLDGAS 324
Cdd:PRK12462 245 AIYVMALVLRWIRDEiGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPR----LDTLFKEQST 320
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 27881918 325 KLGMISLKGHRSVGGIRASLYNAVTVEDVKILAAYMEDFLRNH 367
Cdd:PRK12462 321 EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRH 363
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
8-356 |
4.57e-74 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 234.06 E-value: 4.57e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAQKELLDYSGTGISilEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSgQFSAVPL 87
Cdd:pfam00266 3 LDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGTTE-AINLVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLI-GLKEERCADYLVTGTWSAR-AAKEAEKYGKVNVIHPKLDSYTKI-PDSSTWSLNPSASYVYYCCNETVHGVeFNFI 164
Cdd:pfam00266 80 SLGrSLKPGDEIVITEMEHHANLvPWQELAKRTGARVRVLPLDEDGLLdLDELEKLITPKTKLVAITHVSNVTGT-IQPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 165 PD------TKGVILVSDMSSNFLSRPVDVSKFG--LIFAGAQKNVGCAGVTVVIVREDLIGKA--------LKECPiILD 228
Cdd:pfam00266 159 PEigklahQYGALVLVDAAQAIGHRPIDVQKLGvdFLAFSGHKLYGPTGIGVLYGRRDLLEKMppllggggMIETV-SLQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 229 YQVQAGNNSLYN--TPPCFSIYIMGLVLEWIrNNGGADAMERLNKQKSALVYDIInRSNGFYSCPVDAACRSRMNIPFRI 306
Cdd:pfam00266 238 ESTFADAPWKFEagTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERL-LSLPGIRLYGPERRASIISFNFKG 315
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 27881918 307 gkkeGDESLEKSFLDGA-------SKLGMISLKGHRSVGGIRASLYNAVTVEDVKIL 356
Cdd:pfam00266 316 ----VHPHDVATLLDESgiavrsgHHCAQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
8-298 |
1.47e-09 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 59.04 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 8 NFGAGPAKLPQSVLLQAqkelLDysgtgISILEMSHRSSDFTKIINTTENLIRELLNVPENYKILFLQGGGSGQFSAVPL 87
Cdd:PRK03080 15 RFSSGPCKKRPGWQLEA----LA-----DALLGRSHRQKPVKALLKRVIEGTRELLSLPEGYEVGIVPGSDTGAWEMALW 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 88 NLIGlkeERCADYLVTGTWSARAAKEAEKygkvnviHPKLD-------SYTKIPDSStwSLNPSASYVyYCCNETVHGVE 160
Cdd:PRK03080 86 SLLG---ARRVDHLAWESFGSKWATDVVK-------QLKLEdprvleaDYGSLPDLS--AVDFDRDVV-FTWNGTTTGVR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 161 ---FNFIPDTKGVILVSDMSSNFLSRPVDVSKFGLIFAGAQKNVGC-AGVTVVIV------REDLIGKAlKECPIILDYQ 230
Cdd:PRK03080 153 vpvARWIGADREGLTICDATSAAFALPLDWSKLDVYTFSWQKVLGGeGGHGMAILspraveRLESYTPA-RPIPKFFRLT 231
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 27881918 231 --VQAGNNSL----YNTPPCFSIYIMGLVLEWIRNNGGADAMERLNKQKSALVYDIINRSNgfYSCP--VDAACRS 298
Cdd:PRK03080 232 kgGKAIENSFkgqtINTPSMLTVEDYLDQLDWANSIGGLDALIARTAANASVLYDWAEKTP--WATPlvADPATRS 305
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
56-212 |
2.93e-06 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 46.99 E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 56 ENLIRELLNvPENYKILFlQGGGSGQFSAVPLNLIGLKEErcADYLVTGTWSARAAKEAEKYGKVNVI------HPKLDS 129
Cdd:cd01494 6 EEKLARLLQ-PGNDKAVF-VPSGTGANEAALLALLGPGDE--VIVDANGHGSRYWVAAELAGAKPVPVpvddagYGGLDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 130 YTKIPdsstWSLNPSASYVYYCCNETVHGV-----EFNFIPDTKGVILVSDMSSNFLSRP-----VDVSKFGLIFAGAQK 199
Cdd:cd01494 82 AILEE----LKAKPNVALIVITPNTTSGGVlvplkEIRKIAKEYGILLLVDAASAGGASPapgvlIPEGGADVVTFSLHK 157
|
170
....*....|...
gi 27881918 200 NVGCAGVTVVIVR 212
Cdd:cd01494 158 NLGGEGGGVVIVK 170
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
9-221 |
1.36e-05 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 46.51 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 9 FGAGPAKLPQSVLLQAQKELLDysgtgisilemsHRSSDFTKIINTTENLIRELLNvPENYKILFLQGGGSGQFSAVPLN 88
Cdd:cd06451 3 LIPGPSNVPPRVLKAMNRPMLG------------HRSPEFLALMDEILEGLRYVFQ-TENGLTFLLSGSGTGAMEAALSN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27881918 89 LIglkeERCADYLV--TGTWSARAAKEAEKYG-KVNVIHPKLDSYTKIPDSSTWSLNPSASYVYYCCNETVHGVEFnfip 165
Cdd:cd06451 70 LL----EPGDKVLVgvNGVFGDRWADMAERYGaDVDVVEKPWGEAVSPEEIAEALEQHDIKAVTLTHNETSTGVLN---- 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 27881918 166 DTKGV---------ILVSDMSSNFLSRPVDVSKFGL--IFAGAQKNVGC-AGVTVVIVREDLIGKALK 221
Cdd:cd06451 142 PLEGIgalakkhdaLLIVDAVSSLGGEPFRMDEWGVdvAYTGSQKALGApPGLGPIAFSERALERIKK 209
|
|
| |
