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Conserved domains on  [gi|302849396|ref|XP_002956228|]
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uncharacterized protein VOLCADRAFT_109344 [Volvox carteri f. nagariensis]

Protein Classification

PLN00154 family protein( domain architecture ID 11476415)

PLN00154 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00154 PLN00154
histone H2A; Provisional
 1-137 5.06e-72

histone H2A; Provisional


:

Pssm-ID: 177756  Cd Length: 136  Bit Score: 212.11  E-value: 5.06e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396   1 MSGKGAKGLSGKGAKGTMGDKLKGDKKkPTSRSAKAGLQFPVGRIHRLLKSRVTANGRVGATSAVYAAAILEYLTAEVLE 80
Cdd:PLN00154   1 MSGKGGKGLLAAKTTAAAAKKDKDKKK-PTSRSSRAGLQFPVGRIHRQLKQRVSAHGRVGATAAVYTAAILEYLTAEVLE 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 302849396  81 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKATIAGGGVIPHIHKSLISKQQKK 137
Cdd:PLN00154  80 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKGTIAGGGVIPHIHKSLINKSTKK 136
 
Name Accession Description Interval E-value
PLN00154 PLN00154
histone H2A; Provisional
 1-137 5.06e-72

histone H2A; Provisional


Pssm-ID: 177756  Cd Length: 136  Bit Score: 212.11  E-value: 5.06e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396   1 MSGKGAKGLSGKGAKGTMGDKLKGDKKkPTSRSAKAGLQFPVGRIHRLLKSRVTANGRVGATSAVYAAAILEYLTAEVLE 80
Cdd:PLN00154   1 MSGKGGKGLLAAKTTAAAAKKDKDKKK-PTSRSSRAGLQFPVGRIHRQLKQRVSAHGRVGATAAVYTAAILEYLTAEVLE 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 302849396  81 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKATIAGGGVIPHIHKSLISKQQKK 137
Cdd:PLN00154  80 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKGTIAGGGVIPHIHKSLINKSTKK 136
H2A smart00414
Histone 2A;
31-136 5.23e-55

Histone 2A;


Pssm-ID: 197711  Cd Length: 106  Bit Score: 167.90  E-value: 5.23e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396    31 SRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELD 110
Cdd:smart00414   1 SRSARAGLQFPVGRIHRLLRKGTYAK-RVGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKRRITPRHLQLAIRNDEELN 79

                           90       100
                   ....*....|....*....|....*..
gi 302849396   111 TLIKA-TIAGGGVIPHIHKSLISKQQK 136
Cdd:smart00414  80 KLLKGvTIAQGGVLPNIHKVLLPKKTG 106
HFD_H2A cd00074
histone-fold domain found in histone H2A and similar proteins; Histone H2A is the core ...
 30-117 4.49e-45

histone-fold domain found in histone H2A and similar proteins; Histone H2A is the core component of the nucleosome, which wraps and compacts DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.


Pssm-ID: 467020  Cd Length: 89  Bit Score: 142.29  E-value: 4.49e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  30 TSRSAKAGLQFPVGRIHRLLKSRVTAnGRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEEL 109
Cdd:cd00074    1 QSRSKRAGLQFPVGRIHRLLKKGTYA-KRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKKRITPRHIQLAIRNDEEL 79


                 ....*...
gi 302849396 110 DTLIKATI 117
Cdd:cd00074   80 NKLFKGVT 87
HTA1 COG5262
Histone H2A [Chromatin structure and dynamics];
11-141 4.22e-44

Histone H2A [Chromatin structure and dynamics];


Pssm-ID: 227587 [Multi-domain]  Cd Length: 132  Bit Score: 141.15  E-value: 4.22e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  11 GKGAKGTMGDKLKgdkkkptSRSAKAGLQFPVGRIHRLLKsRVTANGRVGATSAVYAAAILEYLTAEVLELAGNASKDLK 90
Cdd:COG5262    5 GKGGKAADARVSQ-------SRSAKAGLIFPVGRVKRLLK-KGNYRMRIGAGAPVYLAAVLEYLAAEILELAGNAARDNK 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 302849396  91 VKRITPRHLQLAIRGDEELDTLIK-ATIAGGGVIPHIHKSLISKQQKKEGVP 141
Cdd:COG5262   77 KKRIIPRHLQLAIRNDEELNKLLGdVTIAQGGVLPNINPGLLPKSSKKGSKR 128
Histone pfam00125
Core histone H2A/H2B/H3/H4;
31-106 1.70e-16

Core histone H2A/H2B/H3/H4;


Pssm-ID: 459682 [Multi-domain]  Cd Length: 126  Bit Score: 70.54  E-value: 1.70e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302849396   31 SRSAKAGLQFPVGRIHRLLKSRVTANGRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGD 106
Cdd:pfam00125  51 SSTDLLIYKLPFARVVREVVQSTKTDLRISADAVVALQEAVEDFLVELFEEANLLAIHAKRVTLTPKDIQLARRLR 126
 
Name Accession Description Interval E-value
PLN00154 PLN00154
histone H2A; Provisional
 1-137 5.06e-72

histone H2A; Provisional


Pssm-ID: 177756  Cd Length: 136  Bit Score: 212.11  E-value: 5.06e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396   1 MSGKGAKGLSGKGAKGTMGDKLKGDKKkPTSRSAKAGLQFPVGRIHRLLKSRVTANGRVGATSAVYAAAILEYLTAEVLE 80
Cdd:PLN00154   1 MSGKGGKGLLAAKTTAAAAKKDKDKKK-PTSRSSRAGLQFPVGRIHRQLKQRVSAHGRVGATAAVYTAAILEYLTAEVLE 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 302849396  81 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKATIAGGGVIPHIHKSLISKQQKK 137
Cdd:PLN00154  80 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKGTIAGGGVIPHIHKSLINKSTKK 136
PTZ00017 PTZ00017
histone H2A; Provisional
 1-141 6.21e-62

histone H2A; Provisional


Pssm-ID: 185399  Cd Length: 134  Bit Score: 186.49  E-value: 6.21e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396   1 MSGKGAKGlSGKGAKGTmgdklkgdkkkPTSRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYLTAEVLE 80
Cdd:PTZ00017   1 KGGKGKTG-GGKAGKKK-----------PVSRSAKAGLQFPVGRVHRYLKKGRYAK-RVGAGAPVYLAAVLEYLTAEVLE 67

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 302849396  81 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLI-KATIAGGGVIPHIHKSLISKQQKKEGVP 141
Cdd:PTZ00017  68 LAGNAAKDNKKKRITPRHIQLAIRNDEELNKLLaGVTIASGGVLPNIHKVLLPKKSKPKQGK 129
H2A smart00414
Histone 2A;
31-136 5.23e-55

Histone 2A;


Pssm-ID: 197711  Cd Length: 106  Bit Score: 167.90  E-value: 5.23e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396    31 SRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELD 110
Cdd:smart00414   1 SRSARAGLQFPVGRIHRLLRKGTYAK-RVGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKRRITPRHLQLAIRNDEELN 79

                           90       100
                   ....*....|....*....|....*..
gi 302849396   111 TLIKA-TIAGGGVIPHIHKSLISKQQK 136
Cdd:smart00414  80 KLLKGvTIAQGGVLPNIHKVLLPKKTG 106
HFD_H2A cd00074
histone-fold domain found in histone H2A and similar proteins; Histone H2A is the core ...
 30-117 4.49e-45

histone-fold domain found in histone H2A and similar proteins; Histone H2A is the core component of the nucleosome, which wraps and compacts DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.


Pssm-ID: 467020  Cd Length: 89  Bit Score: 142.29  E-value: 4.49e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  30 TSRSAKAGLQFPVGRIHRLLKSRVTAnGRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEEL 109
Cdd:cd00074    1 QSRSKRAGLQFPVGRIHRLLKKGTYA-KRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKKRITPRHIQLAIRNDEEL 79


                 ....*...
gi 302849396 110 DTLIKATI 117
Cdd:cd00074   80 NKLFKGVT 87
HTA1 COG5262
Histone H2A [Chromatin structure and dynamics];
11-141 4.22e-44

Histone H2A [Chromatin structure and dynamics];


Pssm-ID: 227587 [Multi-domain]  Cd Length: 132  Bit Score: 141.15  E-value: 4.22e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  11 GKGAKGTMGDKLKgdkkkptSRSAKAGLQFPVGRIHRLLKsRVTANGRVGATSAVYAAAILEYLTAEVLELAGNASKDLK 90
Cdd:COG5262    5 GKGGKAADARVSQ-------SRSAKAGLIFPVGRVKRLLK-KGNYRMRIGAGAPVYLAAVLEYLAAEILELAGNAARDNK 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 302849396  91 VKRITPRHLQLAIRGDEELDTLIK-ATIAGGGVIPHIHKSLISKQQKKEGVP 141
Cdd:COG5262   77 KKRIIPRHLQLAIRNDEELNKLLGdVTIAQGGVLPNINPGLLPKSSKKGSKR 128
PLN00157 PLN00157
histone H2A; Provisional
 1-139 3.20e-40

histone H2A; Provisional


Pssm-ID: 177758  Cd Length: 132  Bit Score: 131.51  E-value: 3.20e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396   1 MSGKGaKGLSGKGAKgtmgdklkgdkkKPTSRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYLTAEVLE 80
Cdd:PLN00157   1 MSGRG-KRKGGGGGK------------KATSRSAKAGLQFPVGRIARYLKAGKYAT-RVGAGAPVYLAAVLEYLAAEVLE 66

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  81 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLIK-ATIAGGGVIPHIHKSLISKQQKKEG 139
Cdd:PLN00157  67 LAGNAARDNKKSRIVPRHIQLAVRNDEELSKLLGgVTIAAGGVLPNIHSVLLPKKSGKSK 126
PLN00156 PLN00156
histone H2AX; Provisional
 5-139 3.28e-36

histone H2AX; Provisional


Pssm-ID: 215080  Cd Length: 139  Bit Score: 121.23  E-value: 3.28e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396   5 GAKGLSGKGAKGtmgdklKGDKKKPTSRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYLTAEVLELAGN 84
Cdd:PLN00156   1 GAGSGTTKGGRG------KPKATKSVSRSSKAGLQFPVGRIARFLKAGKYAE-RVGAGAPVYLSAVLEYLAAEVLELAGN 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 302849396  85 ASKDLKVKRITPRHLQLAIRGDEELDTLIKA-TIAGGGVIPHIHKSLISKQQKKEG 139
Cdd:PLN00156  74 AARDNKKNRIVPRHIQLAVRNDEELSKLLGSvTIAAGGVLPNIHQTLLPKKVGKGK 129
PLN00153 PLN00153
histone H2A; Provisional
 1-136 7.86e-32

histone H2A; Provisional


Pssm-ID: 165721 [Multi-domain]  Cd Length: 129  Bit Score: 109.81  E-value: 7.86e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396   1 MSGKGAKGLSGKGAkgtmgdklkgdkkkpTSRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYLTAEVLE 80
Cdd:PLN00153   1 MAGRGKGKTSGKKA---------------VSRSAKAGLQFPVGRIARYLKKGKYAE-RIGAGAPVYLAAVLEYLTAEVLE 64

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 302849396  81 LAGNASKDLKVKRITPRHLQLAIRGDEELDTLI-KATIAGGGVIPHIHKSLISKQQK 136
Cdd:PLN00153  65 LAGNAARDNKKNRIVPRHIQLAIRNDEELGKLLgEVTIASGGVLPNIHAVLLPKKTK 121
PTZ00252 PTZ00252
histone H2A; Provisional
 30-135 1.29e-23

histone H2A; Provisional


Pssm-ID: 240330  Cd Length: 134  Bit Score: 89.25  E-value: 1.29e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  30 TSRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYLTAEVLELAGNAS--KDLKVKRITPRHLQLAIRGDE 107
Cdd:PTZ00252  16 SGRSAKAGLIFPVGRVGSLLRRGQYAR-RIGASGAVYMAAVLEYLTAELLELSVKAAaqQAKKPKRLTPRTVTLAVRHDD 94

                         90       100
                 ....*....|....*....|....*....
gi 302849396 108 ELDTLIK-ATIAGGGVIPHIHKSLISKQQ 135
Cdd:PTZ00252  95 DLGSLLKnVTLSRGGVMPSLNKALAKKHK 123
Histone pfam00125
Core histone H2A/H2B/H3/H4;
31-106 1.70e-16

Core histone H2A/H2B/H3/H4;


Pssm-ID: 459682 [Multi-domain]  Cd Length: 126  Bit Score: 70.54  E-value: 1.70e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302849396   31 SRSAKAGLQFPVGRIHRLLKSRVTANGRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGD 106
Cdd:pfam00125  51 SSTDLLIYKLPFARVVREVVQSTKTDLRISADAVVALQEAVEDFLVELFEEANLLAIHAKRVTLTPKDIQLARRLR 126
HFD_SOS1_rpt2 cd22915
second histone-fold domain found in son of sevenless homolog 1 (SOS-1) and similar proteins; ...
 40-109 3.90e-14

second histone-fold domain found in son of sevenless homolog 1 (SOS-1) and similar proteins; SOS-1 is a guanine nucleotide exchange factor for Ras that binds to GRB2. It promotes the exchange of Ras-bound GDP by GTP. It is a catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac, by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity. SOS-1 contains tandem histone folds at the N-terminal region. The model corresponds to the second repeat.


Pssm-ID: 467040  Cd Length: 75  Bit Score: 63.03  E-value: 3.90e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  40 FPVGRIHRLLKsRVTANGRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEEL 109
Cdd:cd22915    2 FPVDKIHPLLK-KDLLVYKVDPQVSLYLVAVLEYIAADILKLAGNYVRNIRHYEITSQDIKVAMCADKVL 70
HFD_ABTB2-like cd22913
histone-fold domain found in ankyrin repeat and BTB/POZ domain-containing protein 2 (ABTB2) ...
 30-109 1.02e-11

histone-fold domain found in ankyrin repeat and BTB/POZ domain-containing protein 2 (ABTB2) and similar proteins; ABTB2, also called Bood POZ containing gene type 2 (BPOZ-2), is a scaffold protein that controls the degradation of many biological proteins ranging from embryonic development to tumor progression. It may be involved in the initiation of hepatocyte growth. It inhibits the aggregation of alpha-synuclein, which has implications for Parkinson's disease. ABTB2 functions as an adaptor protein for the E3 ubiquitin ligase scaffold protein Cullin-3. It directly binds to eukaryotic elongation factor 1A1 (eEF1A1) to promote eEF1A1 ubiquitylation and degradation and prevent translation. It is also involved in the growth suppressive effect of the phosphatase and tensin homolog (PTEN). This subfamily also includes BTB/POZ domain-containing protein 11 (BTBD11), also called ankyrin repeat and BTB/POZ domain-containing protein BTBD11. It is a BTB-domain-containing Kelch-like protein with unknown function.


Pssm-ID: 467038  Cd Length: 105  Bit Score: 57.69  E-value: 1.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302849396  30 TSRSAKAGLQFPVGRIHR-LLKSRVTAngRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEE 108
Cdd:cd22913    9 RSKSARCGLTFSVGRFHRwMVDSRLAK--RIHEHAAVYLTACMENLLEEIFLRALASLVPKGELELTVEALEYGINNDAE 86


                 .
gi 302849396 109 L 109
Cdd:cd22913   87 L 87
Histone_H2A_C pfam16211
C-terminus of histone H2A;
107-137 3.64e-09

C-terminus of histone H2A;


Pssm-ID: 465070  Cd Length: 35  Bit Score: 49.07  E-value: 3.64e-09
                          10        20        30
                  ....*....|....*....|....*....|..
gi 302849396  107 EELDTLIK-ATIAGGGVIPHIHKSLISKQQKK 137
Cdd:pfam16211   1 EELNKLLRgVTIAQGGVLPNIHKVLLPKKTKK 32
PLN00155 PLN00155
histone H2A; Provisional
 1-74 8.52e-09

histone H2A; Provisional


Pssm-ID: 165723  Cd Length: 58  Bit Score: 48.94  E-value: 8.52e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 302849396   1 MSGKGAKGLSGKGAkgtmgdklkgdkkkpTSRSAKAGLQFPVGRIHRLLKSRVTANgRVGATSAVYAAAILEYL 74
Cdd:PLN00155   1 MAGRGKGKTSGKKA---------------VSRSAKAGLQFPVGRIARYLKKGKYAE-RIGAGAPVYLAAVLEYL 58
BUR6 COG5247
Class 2 transcription repressor NC2, alpha subunit (DRAP1 homolog) [Transcription];
39-112 4.23e-06

Class 2 transcription repressor NC2, alpha subunit (DRAP1 homolog) [Transcription];


Pssm-ID: 227572  Cd Length: 113  Bit Score: 43.03  E-value: 4.23e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 302849396  39 QFPVGRIHRLLKSRVTAnGRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDTL 112
Cdd:COG5247   23 RFPIARLKKIMQLDEDI-GKVGQSTPVIASKALEMFLTEIVGLSLKEARKKSSKRMTSEFLKRATESDEKFDFL 95
HFD_DRAP1 cd22906
histone-fold domain found in Dr1-associated protein 1 (DRAP1) and similar proteins; DRAP1, ...
 40-112 2.91e-03

histone-fold domain found in Dr1-associated protein 1 (DRAP1) and similar proteins; DRAP1, also called Dr1-associated corepressor or negative cofactor 2-alpha (NC2-alpha), acts as a corepressor for Dr1 (down-regulator of transcription 1)-mediated repression of transcription. It forms a heterodimer with Dr1. The association of the Dr1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. DRAP1 can bind to DNA on its own. It also binds TATA-binding protein-associated factor 172 (BTAF1).


Pssm-ID: 467031 [Multi-domain]  Cd Length: 75  Bit Score: 34.42  E-value: 2.91e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 302849396  40 FPVGRIHRLLKS--RVtanGRVGATSAVYAAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDTL 112
Cdd:cd22906    4 FPAARIKKIMQSdeEV---GKVAAAVPVLISKALELFLEDLLTKAAEVAKERNAKTITPSHLKQCVESEEKFDFL 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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