CCN family member 1 precursor [Homo sapiens]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
TSP1_CCN | pfam19035 | CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ... |
229-272 | 2.13e-18 | |||
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains. : Pssm-ID: 436914 Cd Length: 44 Bit Score: 77.69 E-value: 2.13e-18
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GHB_like super family | cl21545 | Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the ... |
293-375 | 2.78e-13 | |||
Glycoprotein hormone beta chain homologues; This family of cystine-knot hormones includes the beta chains of gonadotropins, thyrotropins, follitropins, choriogonadotropins and more. The members are reproductive hormones that consist of two glycosylated chains (alpha and beta), which form a tightly bound dimer. The actual alignment was detected with superfamily member pfam00007: Pssm-ID: 451304 Cd Length: 105 Bit Score: 65.50 E-value: 2.78e-13
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IGFBP | pfam00219 | Insulin-like growth factor binding protein; |
26-78 | 3.15e-10 | |||
Insulin-like growth factor binding protein; : Pssm-ID: 425534 Cd Length: 53 Bit Score: 55.04 E-value: 3.15e-10
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VWC | smart00214 | von Willebrand factor (vWF) type C domain; |
100-159 | 4.66e-09 | |||
von Willebrand factor (vWF) type C domain; : Pssm-ID: 214564 Cd Length: 59 Bit Score: 52.13 E-value: 4.66e-09
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Name | Accession | Description | Interval | E-value | |||
TSP1_CCN | pfam19035 | CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ... |
229-272 | 2.13e-18 | |||
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains. Pssm-ID: 436914 Cd Length: 44 Bit Score: 77.69 E-value: 2.13e-18
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Cys_knot | pfam00007 | Cystine-knot domain; The family comprises glycoprotein hormones and the C-terminal domain of ... |
293-375 | 2.78e-13 | |||
Cystine-knot domain; The family comprises glycoprotein hormones and the C-terminal domain of various extracellular proteins. It is believed to be involved in disulfide-linked dimerization. Pssm-ID: 394966 Cd Length: 105 Bit Score: 65.50 E-value: 2.78e-13
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CT | smart00041 | C-terminal cystine knot-like domain (CTCK); The structures of transforming growth factor-beta ... |
292-360 | 1.15e-10 | |||
C-terminal cystine knot-like domain (CTCK); The structures of transforming growth factor-beta (TGFbeta), nerve growth factor (NGF), platelet-derived growth factor (PDGF) and gonadotropin all form 2 highly twisted antiparallel pairs of beta-strands and contain three disulphide bonds. The domain is non-globular and little is conserved among these presumed homologues except for their cysteine residues. CT domains are predicted to form homodimers. Pssm-ID: 214482 Cd Length: 82 Bit Score: 57.41 E-value: 1.15e-10
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IGFBP | pfam00219 | Insulin-like growth factor binding protein; |
26-78 | 3.15e-10 | |||
Insulin-like growth factor binding protein; Pssm-ID: 425534 Cd Length: 53 Bit Score: 55.04 E-value: 3.15e-10
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VWC | smart00214 | von Willebrand factor (vWF) type C domain; |
100-159 | 4.66e-09 | |||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214564 Cd Length: 59 Bit Score: 52.13 E-value: 4.66e-09
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
100-160 | 6.22e-08 | |||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 48.96 E-value: 6.22e-08
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IB | smart00121 | Insulin growth factor-binding protein homologues; High affinity binding partners of ... |
32-84 | 1.47e-07 | |||
Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors. Pssm-ID: 197525 Cd Length: 75 Bit Score: 48.23 E-value: 1.47e-07
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TSP1 | smart00209 | Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
232-272 | 7.88e-04 | |||
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 37.18 E-value: 7.88e-04
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Name | Accession | Description | Interval | E-value | |||
TSP1_CCN | pfam19035 | CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ... |
229-272 | 2.13e-18 | |||
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains. Pssm-ID: 436914 Cd Length: 44 Bit Score: 77.69 E-value: 2.13e-18
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Cys_knot | pfam00007 | Cystine-knot domain; The family comprises glycoprotein hormones and the C-terminal domain of ... |
293-375 | 2.78e-13 | |||
Cystine-knot domain; The family comprises glycoprotein hormones and the C-terminal domain of various extracellular proteins. It is believed to be involved in disulfide-linked dimerization. Pssm-ID: 394966 Cd Length: 105 Bit Score: 65.50 E-value: 2.78e-13
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CT | smart00041 | C-terminal cystine knot-like domain (CTCK); The structures of transforming growth factor-beta ... |
292-360 | 1.15e-10 | |||
C-terminal cystine knot-like domain (CTCK); The structures of transforming growth factor-beta (TGFbeta), nerve growth factor (NGF), platelet-derived growth factor (PDGF) and gonadotropin all form 2 highly twisted antiparallel pairs of beta-strands and contain three disulphide bonds. The domain is non-globular and little is conserved among these presumed homologues except for their cysteine residues. CT domains are predicted to form homodimers. Pssm-ID: 214482 Cd Length: 82 Bit Score: 57.41 E-value: 1.15e-10
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IGFBP | pfam00219 | Insulin-like growth factor binding protein; |
26-78 | 3.15e-10 | |||
Insulin-like growth factor binding protein; Pssm-ID: 425534 Cd Length: 53 Bit Score: 55.04 E-value: 3.15e-10
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VWC | smart00214 | von Willebrand factor (vWF) type C domain; |
100-159 | 4.66e-09 | |||
von Willebrand factor (vWF) type C domain; Pssm-ID: 214564 Cd Length: 59 Bit Score: 52.13 E-value: 4.66e-09
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VWC | pfam00093 | von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
100-160 | 6.22e-08 | |||
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094. Pssm-ID: 278520 Cd Length: 57 Bit Score: 48.96 E-value: 6.22e-08
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IB | smart00121 | Insulin growth factor-binding protein homologues; High affinity binding partners of ... |
32-84 | 1.47e-07 | |||
Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors. Pssm-ID: 197525 Cd Length: 75 Bit Score: 48.23 E-value: 1.47e-07
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TSP1_spondin | pfam19028 | Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
234-272 | 7.78e-04 | |||
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain. Pssm-ID: 436909 [Multi-domain] Cd Length: 52 Bit Score: 37.25 E-value: 7.78e-04
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TSP1 | smart00209 | Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
232-272 | 7.88e-04 | |||
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 37.18 E-value: 7.88e-04
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TSP1_ADAMTS | pfam19030 | Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
233-272 | 1.29e-03 | |||
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins. Pssm-ID: 408800 [Multi-domain] Cd Length: 55 Bit Score: 36.66 E-value: 1.29e-03
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Blast search parameters | ||||
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