|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
2-1453 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 2711.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 2 MDSKSNVGDSATMPMPPELYHGALLQPASPHRNSASTAPFSEKRGQLHSCHGVPHEDLTREPSEMFQVVIDGDDGGVEMR 81
Cdd:PTZ00310 1 TDSQSKVSGGATFPISPELSHGHLRQPASSHSGSFSEFRFSDRAQRLFSGHGAPEVSLAAVASTMFRVVIDGDDGGVDMR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 82 RVHDRIETALRVRSLYRPLETRVGGRERANPYMSAPMPGRITIVQKDGVYQVSDHDASLFLPiPTWSQYATDVQKVRLTV 161
Cdd:PTZ00310 81 KVHGRIAAAIRVRQLYKPTDTKVPEGEREQPSDSTPMPSLVTIVQRDGVYRFSGMDTSVVLP-PPWEQYVRDVQAVYLTV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 162 GNAGCVNACHHRLGIMQERSRMFFLLNAGMEERANYHKAGGVFSAARKVDNAVLLSESMDAQELLEGVKEMYRRSPEAAV 241
Cdd:PTZ00310 160 GNGPCLSACRHRLTIIQERSRMFFLLNAEIEERADLYKAGGVFSPCTKVDNAVLLSTSVDAQELLEFVVTTYREQPRAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 242 HLRNGSNSTLRELLGAHGVRSADDLTVAGLGWQAEKDAPHQGQIDLADCE-SMAALGAELRFSFTELQGYLCEKVLRRVV 320
Cdd:PTZ00310 240 RLRDGSNSTLREYLEAHGVRDPRELTVEGLGWQPTKYRNKYGQYDLFDAKnPMGALGAELRQSFLSLHGNLCGKLLRREL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 321 SRAERPSLTPQAAEYSVPLYGLQSSELSYLAELMQRRLEGPHPRVQYILSICFTESPPFEVVSSCTTLQDQLDNIFLALF 400
Cdd:PTZ00310 320 ERREYQKQQPQATEYSLPLYGHHPEELTDLAEWVRRQGFGPFSRNRWILAISFKELGPFQVPSSCTTVQDQLDNIFLPLF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 401 KATLAPEDPSNAGVAWLLGQVGGLQMLHAQDGPGRDFDEMAPPPDQVKIGAKQSGLYYMYYLYANLAVLNSLRRRKGLEP 480
Cdd:PTZ00310 400 KATLCPSDPQWSDVAWLLCQVGGLQILTHAVVRSEDFDETAPDPDQVPYTAKCSDLYYFYYVYANLAVLNSLRKRKGLNT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 481 LQLRCTGNKPTGMDDLIGAYILSDVITRATKITDYPVLQYLCGLHRVGLTVSPLCDHMEGIVAYKDHPLPHFLHRCLHIT 560
Cdd:PTZ00310 480 LQLRPSGEKAPAYDQLISSYLLGDVITRATSIADYPVLQYLCGLHRVGLTVSPLRDHALSITAYFDHPLPKFLHRCLRVS 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 561 LSTESPLRYHHNPRALIEEYATAQKMFRLSSLDMTELAHNSVLMSSFSPEVKRQWLGDKYQLGVEGNEFELSHVTNARLA 640
Cdd:PTZ00310 560 ISTSDPLYFHHHSQPLIEEYATAMKLFSLSPLDTTELARNSVLNSSFPPEVKQQWLGERFQLGVEGNDFERSGVTNYRLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 641 FRDEAWQLERNMMRDLNLN-PSHEVGAGLSRWHHLSNVQEVEYDTVMDSRVRFPRTVLKGPHKDAKAVTAAPRVARALDL 719
Cdd:PTZ00310 640 FREEAWALEEALLNDLLLNvPSGDSGAGPSRWHYISNVQEVEYDTVLDQRVRFPRTVLYGPHKSGKAVTAAPALARALDL 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 720 RHQYIWCPPPPWETAQRHGVETDFQRRTATFNEDEWTYAASDAVFIAYPKSAVHAWPRSLPTLDDFHKHLRELRDICASA 799
Cdd:PTZ00310 720 RHKYIWNPPPPWETTQRNVVEEDFQRTTRQFNEDQWTYAAYDGVFILSPKGAVHAWPRFLPTLTEFIRDLSELRDICSSV 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 800 EVKEYAHKRLENLDHKFRLHLALNHENEAGTTEDRQSSNRDFYQATKVDTHIHMAAGMTPKQILKFVLAKLKESGDDIAM 879
Cdd:PTZ00310 800 EVKRLATKRLENLEHKFRLHLALNHSNEAGTTEERESSNRDFYQAYKVDTHIHMAAGMTARQLLEFVVDKLLESGDDIAF 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 880 KKGDDIFTLGQLFAKAGITPNLTVDQLNVQADHTLFERFDNFNSKYNPMENGDLRSLLLKTDNFMNGRYFAELIHDVFEQ 959
Cdd:PTZ00310 880 KRGDHIVTLGQLFSKYGITPNLTVDQLNVQADHTLFERFDNFNSKYNPMENPDLRSLLLKTDNFMKGRYFAELIKDVFEQ 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 960 YSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPRVYKVFRAQNVIGSFGQYLQNIFQPLWEASLHP 1039
Cdd:PTZ00310 960 YSRDRFTYAENRLSIYGINVKEWDDLAHWFDTHGMASKHNKWMIQVPRVYKVFRAQNVIGSFGQYLDNIFQPLWEASLHP 1039
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1040 SEHPTLHNFLNHVSGFDSVDNEATIDLPFTTVSPWAWTVVENPPYNYYLYYLYANIRTLNEFRASRGFSTFGLRPHCGES 1119
Cdd:PTZ00310 1040 SKHPKFHYFLNHVSGFDSVDNEATIDLPFTDVSPWAWTSVENPPYNYYLYYLYANIRTLNEFRASRGFSTFALRPHCGES 1119
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1120 GSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLHFLSNPFPDFFHRGLNVSLSTDDPMMFHQ 1199
Cdd:PTZ00310 1120 GSMDHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLAFLENPFPVFFHRGLNVSLSTDDPLMFHQ 1199
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1200 TQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIGDRWFLSSSLGNDSLRTHLSDIRVAFRFETYHTEL 1279
Cdd:PTZ00310 1200 TQEPLIEEYSIAARVWGLSLNDLCEIARNSVLQSGFDAAFKRNAIGDRWYLSSSLGNDSLRTHLSDIRVAFRFETYHTEL 1279
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1280 QQLELCCGRPVSRFMMTAAEERAVDVQIVDVQREYVLLSTHDQAMEVMLREMEDTKTKIVQTRAQVDILRRQQRSLLEKI 1359
Cdd:PTZ00310 1280 NFLELCSGRPIPRAMKTLEEELAICEKIVDVRAETVLLSTHDQAMEVMLREMETTNERIVHLRAQVDSLRRQQRSLVERL 1359
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1360 TEMGIRRQEAEEQSAQEEKELPSRKGPLYVREKSQGSQVGGGDGDRSGVLQSPTCPTQQGETLKRLLRWKPMPPDLMRSV 1439
Cdd:PTZ00310 1360 TEEGIRRQEVSEQVAGENNSIALRVNRLRERLQSEGLTVGGGLYGRSNEEESEASSTQQGETVKRLLRWKPMPPDVMRAV 1439
|
1450
....*....|....
gi 323364103 1440 TQASFSSSRGRPLP 1453
Cdd:PTZ00310 1440 TVASVPGSRGRPLP 1453
|
|
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
785-1279 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 608.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 785 FHKHLRELRDICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSSNRDFYQATKVDTHIHMAAGMTPKQILK 864
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRE--LKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 865 FVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFERFDNFNSKYNPMENGDLRSLLLKTDNF 943
Cdd:cd01319 79 FIKKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAyDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 944 MNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPRVYKVFRAQNVIGSFGQ 1023
Cdd:cd01319 159 INGRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1024 YLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNEATIDLPFTTVSPWA--WTVVENPPYNYYLYYLYANIRTLNEF 1101
Cdd:cd01319 239 MLENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESKSERRFTRKFPKPeeWTSEENPPYSYYLYYMYANITTLNSF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1102 RASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLHFLSNPFPDFF 1181
Cdd:cd01319 319 RKARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFF 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1182 HRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIGDRWFLSSSLGNDSLRT 1261
Cdd:cd01319 399 KRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRT 478
|
490
....*....|....*...
gi 323364103 1262 HLSDIRVAFRFETYHTEL 1279
Cdd:cd01319 479 NVPQIRMAYRYETLCEEL 496
|
|
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
707-1279 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 567.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 707 VTAAPRVARALDLRHQYIWCPPPPWETAQRHG-----------------VETDFQRRTATFNED-EWTYAASDAVFIAYP 768
Cdd:pfam19326 22 EEAYKSLAECLEIREKYMFPETTAPYLKSVQGedstpkendepvfhpppKKGEDPYELFNFPPDlGYHLRMQDGVVHVYA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 769 KSAVHAWPRSLPTLDDFHKHLRELRDICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSSNRDFYQATKVD 848
Cdd:pfam19326 102 NKDALEDSLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFNLHLMLNEMKE--LKAQKSNPHRDFYNVRKVD 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 849 THIHMAAGMTPKQILKFVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFERFDNFNSKYNP 927
Cdd:pfam19326 180 THVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTGyDLSVDTLDVHADRDTFHRFDKFNLKYNP 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 928 MENGDLRSLLLKTDNFMNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPR 1007
Cdd:pfam19326 260 IGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRSPDEWDKLASWIVDNKVYSPNVRWLIQVPR 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1008 VYKVFRAQNVIGSFGQYLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNEATIDLPFTTVSPW--AWTVVENPPYN 1085
Cdd:pfam19326 340 LYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSVDDESKPERRMFRKSPKpaLWTNEQNPPYS 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1086 YYLYYLYANIRTLNEFRASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSN 1165
Cdd:pfam19326 420 YYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGISHGILLRKSPVLQYLYYLAQIGIAMSPLSN 499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1166 NALFLHFLSNPFPDFFHRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIG 1245
Cdd:pfam19326 500 NSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSACDMCELARNSVLQSGFSHQLKSHWLG 579
|
570 580 590
....*....|....*....|....*....|....
gi 323364103 1246 DRWFLSSSLGNDSLRTHLSDIRVAFRFETYHTEL 1279
Cdd:pfam19326 580 KDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQEL 613
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
708-1282 |
6.78e-176 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 538.66 E-value: 6.78e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 708 TAAPRVARALDLRHQYIW---------------CPPPPWETAQRHGVET--DFQRRTATFN---------EDEWTYAASD 761
Cdd:TIGR01429 5 EAAKSLAKALMLREKYARlayhrfpdttaqylsHQGYPESVPLEEGLPDfhPPPDPQEDPYcldddappiELGYLVRMHG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 762 AVFIAYPK--SAVHAWPRSL--PTLDDFHKHLRELRDICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSS 837
Cdd:TIGR01429 85 GVLFVYDNdtMLERQEPHFLvpPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSE--LKEQKSVP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 838 NRDFYQATKVDTHIHMAAGMTPKQILKFVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFE 916
Cdd:TIGR01429 163 HRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPyDLSVDTLDVHADRNTFH 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 917 RFDNFNSKYNPMENGDLRSLLLKTDNFMNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMAN 996
Cdd:TIGR01429 243 RFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDHDVFS 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 997 KHNKWIIQVPRVYKVFRAQNVIGSFGQYLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNEATIDLPFTT---VSP 1073
Cdd:TIGR01429 323 PNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSrkfPSP 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1074 WAWTVVENPPYNYYLYYLYANIRTLNEFRASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYL 1153
Cdd:TIGR01429 403 DEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQYLYYL 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1154 AQIGLHVSPLSNNALFLHFLSNPFPDFFHRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQC 1233
Cdd:TIGR01429 483 TQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNSVLQS 562
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 323364103 1234 GFDNNFKCNAIGDRWFLSSSLGNDSLRTHLSDIRVAFRFETYHTELQQL 1282
Cdd:TIGR01429 563 GFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
1111-1230 |
1.29e-17 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 85.91 E-value: 1.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1111 GLR--PHCGESGSEVHLYGA--FLCANSICHGINLRNDPP-MQYLyylA--QIGLHVSPLSNNAL--FLHFLSNPFPDFF 1181
Cdd:COG1816 181 GLHltAHAGEAGGPESIWEAldLLGAERIGHGVRAIEDPAlVARL---AdrGIPLEVCPTSNVQLgvVPSLAEHPLRRLL 257
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 323364103 1182 HRGLNVSLSTDDPMMFHQTqepLIEEYSIAARVWGLSANDLCEIARNSV 1230
Cdd:COG1816 258 DAGVRVTLNTDDPLYFGTT---LTDEYELAAEAFGLSDADLAQLARNAI 303
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
2-1453 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 2711.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 2 MDSKSNVGDSATMPMPPELYHGALLQPASPHRNSASTAPFSEKRGQLHSCHGVPHEDLTREPSEMFQVVIDGDDGGVEMR 81
Cdd:PTZ00310 1 TDSQSKVSGGATFPISPELSHGHLRQPASSHSGSFSEFRFSDRAQRLFSGHGAPEVSLAAVASTMFRVVIDGDDGGVDMR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 82 RVHDRIETALRVRSLYRPLETRVGGRERANPYMSAPMPGRITIVQKDGVYQVSDHDASLFLPiPTWSQYATDVQKVRLTV 161
Cdd:PTZ00310 81 KVHGRIAAAIRVRQLYKPTDTKVPEGEREQPSDSTPMPSLVTIVQRDGVYRFSGMDTSVVLP-PPWEQYVRDVQAVYLTV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 162 GNAGCVNACHHRLGIMQERSRMFFLLNAGMEERANYHKAGGVFSAARKVDNAVLLSESMDAQELLEGVKEMYRRSPEAAV 241
Cdd:PTZ00310 160 GNGPCLSACRHRLTIIQERSRMFFLLNAEIEERADLYKAGGVFSPCTKVDNAVLLSTSVDAQELLEFVVTTYREQPRAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 242 HLRNGSNSTLRELLGAHGVRSADDLTVAGLGWQAEKDAPHQGQIDLADCE-SMAALGAELRFSFTELQGYLCEKVLRRVV 320
Cdd:PTZ00310 240 RLRDGSNSTLREYLEAHGVRDPRELTVEGLGWQPTKYRNKYGQYDLFDAKnPMGALGAELRQSFLSLHGNLCGKLLRREL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 321 SRAERPSLTPQAAEYSVPLYGLQSSELSYLAELMQRRLEGPHPRVQYILSICFTESPPFEVVSSCTTLQDQLDNIFLALF 400
Cdd:PTZ00310 320 ERREYQKQQPQATEYSLPLYGHHPEELTDLAEWVRRQGFGPFSRNRWILAISFKELGPFQVPSSCTTVQDQLDNIFLPLF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 401 KATLAPEDPSNAGVAWLLGQVGGLQMLHAQDGPGRDFDEMAPPPDQVKIGAKQSGLYYMYYLYANLAVLNSLRRRKGLEP 480
Cdd:PTZ00310 400 KATLCPSDPQWSDVAWLLCQVGGLQILTHAVVRSEDFDETAPDPDQVPYTAKCSDLYYFYYVYANLAVLNSLRKRKGLNT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 481 LQLRCTGNKPTGMDDLIGAYILSDVITRATKITDYPVLQYLCGLHRVGLTVSPLCDHMEGIVAYKDHPLPHFLHRCLHIT 560
Cdd:PTZ00310 480 LQLRPSGEKAPAYDQLISSYLLGDVITRATSIADYPVLQYLCGLHRVGLTVSPLRDHALSITAYFDHPLPKFLHRCLRVS 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 561 LSTESPLRYHHNPRALIEEYATAQKMFRLSSLDMTELAHNSVLMSSFSPEVKRQWLGDKYQLGVEGNEFELSHVTNARLA 640
Cdd:PTZ00310 560 ISTSDPLYFHHHSQPLIEEYATAMKLFSLSPLDTTELARNSVLNSSFPPEVKQQWLGERFQLGVEGNDFERSGVTNYRLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 641 FRDEAWQLERNMMRDLNLN-PSHEVGAGLSRWHHLSNVQEVEYDTVMDSRVRFPRTVLKGPHKDAKAVTAAPRVARALDL 719
Cdd:PTZ00310 640 FREEAWALEEALLNDLLLNvPSGDSGAGPSRWHYISNVQEVEYDTVLDQRVRFPRTVLYGPHKSGKAVTAAPALARALDL 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 720 RHQYIWCPPPPWETAQRHGVETDFQRRTATFNEDEWTYAASDAVFIAYPKSAVHAWPRSLPTLDDFHKHLRELRDICASA 799
Cdd:PTZ00310 720 RHKYIWNPPPPWETTQRNVVEEDFQRTTRQFNEDQWTYAAYDGVFILSPKGAVHAWPRFLPTLTEFIRDLSELRDICSSV 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 800 EVKEYAHKRLENLDHKFRLHLALNHENEAGTTEDRQSSNRDFYQATKVDTHIHMAAGMTPKQILKFVLAKLKESGDDIAM 879
Cdd:PTZ00310 800 EVKRLATKRLENLEHKFRLHLALNHSNEAGTTEERESSNRDFYQAYKVDTHIHMAAGMTARQLLEFVVDKLLESGDDIAF 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 880 KKGDDIFTLGQLFAKAGITPNLTVDQLNVQADHTLFERFDNFNSKYNPMENGDLRSLLLKTDNFMNGRYFAELIHDVFEQ 959
Cdd:PTZ00310 880 KRGDHIVTLGQLFSKYGITPNLTVDQLNVQADHTLFERFDNFNSKYNPMENPDLRSLLLKTDNFMKGRYFAELIKDVFEQ 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 960 YSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPRVYKVFRAQNVIGSFGQYLQNIFQPLWEASLHP 1039
Cdd:PTZ00310 960 YSRDRFTYAENRLSIYGINVKEWDDLAHWFDTHGMASKHNKWMIQVPRVYKVFRAQNVIGSFGQYLDNIFQPLWEASLHP 1039
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1040 SEHPTLHNFLNHVSGFDSVDNEATIDLPFTTVSPWAWTVVENPPYNYYLYYLYANIRTLNEFRASRGFSTFGLRPHCGES 1119
Cdd:PTZ00310 1040 SKHPKFHYFLNHVSGFDSVDNEATIDLPFTDVSPWAWTSVENPPYNYYLYYLYANIRTLNEFRASRGFSTFALRPHCGES 1119
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1120 GSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLHFLSNPFPDFFHRGLNVSLSTDDPMMFHQ 1199
Cdd:PTZ00310 1120 GSMDHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLAFLENPFPVFFHRGLNVSLSTDDPLMFHQ 1199
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1200 TQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIGDRWFLSSSLGNDSLRTHLSDIRVAFRFETYHTEL 1279
Cdd:PTZ00310 1200 TQEPLIEEYSIAARVWGLSLNDLCEIARNSVLQSGFDAAFKRNAIGDRWYLSSSLGNDSLRTHLSDIRVAFRFETYHTEL 1279
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1280 QQLELCCGRPVSRFMMTAAEERAVDVQIVDVQREYVLLSTHDQAMEVMLREMEDTKTKIVQTRAQVDILRRQQRSLLEKI 1359
Cdd:PTZ00310 1280 NFLELCSGRPIPRAMKTLEEELAICEKIVDVRAETVLLSTHDQAMEVMLREMETTNERIVHLRAQVDSLRRQQRSLVERL 1359
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1360 TEMGIRRQEAEEQSAQEEKELPSRKGPLYVREKSQGSQVGGGDGDRSGVLQSPTCPTQQGETLKRLLRWKPMPPDLMRSV 1439
Cdd:PTZ00310 1360 TEEGIRRQEVSEQVAGENNSIALRVNRLRERLQSEGLTVGGGLYGRSNEEESEASSTQQGETVKRLLRWKPMPPDVMRAV 1439
|
1450
....*....|....
gi 323364103 1440 TQASFSSSRGRPLP 1453
Cdd:PTZ00310 1440 TVASVPGSRGRPLP 1453
|
|
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
785-1279 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 608.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 785 FHKHLRELRDICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSSNRDFYQATKVDTHIHMAAGMTPKQILK 864
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRE--LKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 865 FVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFERFDNFNSKYNPMENGDLRSLLLKTDNF 943
Cdd:cd01319 79 FIKKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAyDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 944 MNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPRVYKVFRAQNVIGSFGQ 1023
Cdd:cd01319 159 INGRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1024 YLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNEATIDLPFTTVSPWA--WTVVENPPYNYYLYYLYANIRTLNEF 1101
Cdd:cd01319 239 MLENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESKSERRFTRKFPKPeeWTSEENPPYSYYLYYMYANITTLNSF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1102 RASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLHFLSNPFPDFF 1181
Cdd:cd01319 319 RKARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFF 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1182 HRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIGDRWFLSSSLGNDSLRT 1261
Cdd:cd01319 399 KRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRT 478
|
490
....*....|....*...
gi 323364103 1262 HLSDIRVAFRFETYHTEL 1279
Cdd:cd01319 479 NVPQIRMAYRYETLCEEL 496
|
|
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
707-1279 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 567.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 707 VTAAPRVARALDLRHQYIWCPPPPWETAQRHG-----------------VETDFQRRTATFNED-EWTYAASDAVFIAYP 768
Cdd:pfam19326 22 EEAYKSLAECLEIREKYMFPETTAPYLKSVQGedstpkendepvfhpppKKGEDPYELFNFPPDlGYHLRMQDGVVHVYA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 769 KSAVHAWPRSLPTLDDFHKHLRELRDICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSSNRDFYQATKVD 848
Cdd:pfam19326 102 NKDALEDSLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFNLHLMLNEMKE--LKAQKSNPHRDFYNVRKVD 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 849 THIHMAAGMTPKQILKFVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFERFDNFNSKYNP 927
Cdd:pfam19326 180 THVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTGyDLSVDTLDVHADRDTFHRFDKFNLKYNP 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 928 MENGDLRSLLLKTDNFMNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPR 1007
Cdd:pfam19326 260 IGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRSPDEWDKLASWIVDNKVYSPNVRWLIQVPR 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1008 VYKVFRAQNVIGSFGQYLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNEATIDLPFTTVSPW--AWTVVENPPYN 1085
Cdd:pfam19326 340 LYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSVDDESKPERRMFRKSPKpaLWTNEQNPPYS 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1086 YYLYYLYANIRTLNEFRASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSN 1165
Cdd:pfam19326 420 YYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGISHGILLRKSPVLQYLYYLAQIGIAMSPLSN 499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1166 NALFLHFLSNPFPDFFHRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIG 1245
Cdd:pfam19326 500 NSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSACDMCELARNSVLQSGFSHQLKSHWLG 579
|
570 580 590
....*....|....*....|....*....|....
gi 323364103 1246 DRWFLSSSLGNDSLRTHLSDIRVAFRFETYHTEL 1279
Cdd:pfam19326 580 KDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQEL 613
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
708-1282 |
6.78e-176 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 538.66 E-value: 6.78e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 708 TAAPRVARALDLRHQYIW---------------CPPPPWETAQRHGVET--DFQRRTATFN---------EDEWTYAASD 761
Cdd:TIGR01429 5 EAAKSLAKALMLREKYARlayhrfpdttaqylsHQGYPESVPLEEGLPDfhPPPDPQEDPYcldddappiELGYLVRMHG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 762 AVFIAYPK--SAVHAWPRSL--PTLDDFHKHLRELRDICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSS 837
Cdd:TIGR01429 85 GVLFVYDNdtMLERQEPHFLvpPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSE--LKEQKSVP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 838 NRDFYQATKVDTHIHMAAGMTPKQILKFVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFE 916
Cdd:TIGR01429 163 HRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPyDLSVDTLDVHADRNTFH 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 917 RFDNFNSKYNPMENGDLRSLLLKTDNFMNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMAN 996
Cdd:TIGR01429 243 RFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDHDVFS 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 997 KHNKWIIQVPRVYKVFRAQNVIGSFGQYLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNEATIDLPFTT---VSP 1073
Cdd:TIGR01429 323 PNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSrkfPSP 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1074 WAWTVVENPPYNYYLYYLYANIRTLNEFRASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYL 1153
Cdd:TIGR01429 403 DEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQYLYYL 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1154 AQIGLHVSPLSNNALFLHFLSNPFPDFFHRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQC 1233
Cdd:TIGR01429 483 TQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNSVLQS 562
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 323364103 1234 GFDNNFKCNAIGDRWFLSSSLGNDSLRTHLSDIRVAFRFETYHTELQQL 1282
Cdd:TIGR01429 563 GFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| PLN03055 |
PLN03055 |
AMP deaminase; Provisional |
717-1284 |
7.02e-164 |
|
AMP deaminase; Provisional
Pssm-ID: 178613 Cd Length: 602 Bit Score: 506.71 E-value: 7.02e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 717 LDLRHQYIWCPP-PPWEtaqrhgvETDFQRRTATFNEDEWTYAAS----------DAVFIAY----PKSAVHAWPRSLPT 781
Cdd:PLN03055 19 LELRDKYLFREKlPPWR-------KGIFESSTSKPNPDPFRYEPEppsqhvfrmvDGVMHVYapddAKEELFPVPDATTF 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 782 LDDFHKHLRelrdICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSSNRDFYQATKVDTHIHMAAGMTPKQ 861
Cdd:PLN03055 92 FTDMHRILR----IVSLGNVRTFCHHRLKLLEQKFSLHLMLNADRE--FLAQKSAPHRDFYNVRKVDTHVHHSSCMNQKH 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 862 ILKFVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFERFDNFNSKYNPMENGDLRSLLLKT 940
Cdd:PLN03055 166 LLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLDLTGyDLNVDLLDVHADKNTFHRFDKFNLKYNPCGQSRLREIFLKQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 941 DNFMNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPRVYKVFRAQNVIGS 1020
Cdd:PLN03055 246 DNLIQGRFLAELTKEVFSDLEASKYQMAEYRISIYGRKQSEWDQLASWIVNNRLYSENVVWLIQLPRLYNVYKEMGIVQS 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1021 FGQYLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNE--------------ATIDLPFT-TVSPWAWTVvenppyn 1085
Cdd:PLN03055 326 FQQILDNIFKPLFEVTVDPSSHPQLHVFLKMVVGFDMVDDEskperrptkhmqtpEQWDIPFNpAYSYWAYYV------- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1086 yylyylYANIRTLNEFRASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSN 1165
Cdd:PLN03055 399 ------YANLYTLNKLRESKGLNTIKFRPHAGEAGDIDHLAAAFLLAHNIAHGNNLRKSPGLQYLYYLAQIGLAMSPLSN 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1166 NALFLHFLSNPFPDFFHRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIG 1245
Cdd:PLN03055 473 NSLFLDYHRNPFPMFFARGLNVSLSTDDPLQIHLTKEPLVEEYSIAAQVWKLSSCDLCEIARNSVLQSGFPHASKKHWVG 552
|
570 580 590
....*....|....*....|....*....|....*....
gi 323364103 1246 DRWFLSSSLGNDSLRTHLSDIRVAFRFETYHTELQQLEL 1284
Cdd:PLN03055 553 DNYWLRGPAGNDIHKTNVPHMRVEFRHEVWKEELQYVFL 591
|
|
| PLN02768 |
PLN02768 |
AMP deaminase |
717-1284 |
5.18e-153 |
|
AMP deaminase
Pssm-ID: 215411 Cd Length: 835 Bit Score: 485.91 E-value: 5.18e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 717 LDLRHQYIWCPP-PPWETaqrhgvETDFQRRTATFNEDEWTY---AASDAVFiAYPKSAVHAWP------RSLPTLD--- 783
Cdd:PLN02768 251 LELRKRYVFREEvAPWEK------EIISDPSTPKPNPNPFSYtpeGKSDHYF-EMQDGVVHVYAnkdskeELFPVADatt 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 784 ---DFHKHLRelrdICASAEVKEYAHKRLENLDHKFRLHLALNHENEagTTEDRQSSNRDFYQATKVDTHIHMAAGMTPK 860
Cdd:PLN02768 324 fftDLHHILR----VIAAGNIRTLCHHRLNLLEQKFNLHLMLNADRE--FLAQKSAPHRDFYNVRKVDTHVHHSACMNQK 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 861 QILKFVLAKLKESGDDIAMKKGDDIFTLGQLFAKAGITP-NLTVDQLNVQADHTLFERFDNFNSKYNPMENGDLRSLLLK 939
Cdd:PLN02768 398 HLLRFIKSKLRKEPDEVVIFRDGTYLTLKEVFESLDLTGyDLNVDLLDVHADKSTFHRFDKFNLKYNPCGQSRLREIFLK 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 940 TDNFMNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINVKEWDKLAHWFATHGMANKHNKWIIQVPRVYKVFRAQNVIG 1019
Cdd:PLN02768 478 QDNLIQGRFLAELTKQVFSDLEASKYQMAEYRISIYGRKQSEWDQLASWIVNNELYSENVVWLIQLPRLYNVYKEMGIVT 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1020 SFGQYLQNIFQPLWEASLHPSEHPTLHNFLNHVSGFDSVDNEA------TIDLPfttvSPWAWTVVENPPYNYYLYYLYA 1093
Cdd:PLN02768 558 SFQNILDNIFIPLFEVTVDPDSHPQLHVFLKQVVGLDLVDDESkperrpTKHMP----TPAQWTNVFNPAFSYYVYYCYA 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1094 NIRTLNEFRASRGFSTFGLRPHCGESGSEVHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLHFL 1173
Cdd:PLN02768 634 NLYTLNKLRESKGMTTIKFRPHSGEAGDIDHLAATFLTCHNIAHGINLRKSPVLQYLYYLAQIGLAMSPLSNNSLFLDYH 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1174 SNPFPDFFHRGLNVSLSTDDPMMFHQTQEPLIEEYSIAARVWGLSANDLCEIARNSVLQCGFDNNFKCNAIGDRWFLSSS 1253
Cdd:PLN02768 714 RNPFPMFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSSCDLCEIARNSVYQSGFSHALKSHWIGKEYYKRGP 793
|
570 580 590
....*....|....*....|....*....|.
gi 323364103 1254 LGNDSLRTHLSDIRVAFRFETYHTELQQLEL 1284
Cdd:PLN02768 794 DGNDIHKTNVPHIRVEFRDTIWKEEMQQVYL 824
|
|
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
150-650 |
4.49e-75 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 258.84 E-value: 4.49e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 150 YATDVQKVRLTVGNAGCVNACHHRLGIMQERSRMFFLLNaGMEERANYHKAG-GVFSAARKVDNAVLLSESMDAQELLEG 228
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLN-EDRELKEQKTVPhRDFYNVRKVDTHVHHSACMNQKHLLRF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 229 VKEMYRRSPEAAVHLRNGSNSTLRELLGAHGVrSADDLTVAGLGWQAEKDAPHQgqIDLADCESMAALGAELRFSF--TE 306
Cdd:cd01319 80 IKKKLRTEPDEVVIFRDGKKLTLKEVFDSLKL-TAYDLSVDTLDVHADRNTFHR--FDKFNLKYNPIGESRLREIFlkTD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 307 --LQG-YLCEkVLRRVVSRAERPSLtpQAAEYSVPLYGLQSSELSYLAE-LMQRRLEgpHPRVQYILSIcftespP---- 378
Cdd:cd01319 157 nyINGrYLAE-ITKEVFSDLEESKY--QHAEYRLSIYGRSKDEWDKLASwVVDNDLF--SPNVRWLIQI------Prlyd 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 379 -FEVVSSCTTLQDQLDNIFLALFKATLAPEdpSNAGVAWLLGQVGGLQMLHAQDGPGRDFDEMAPPPDQVKIGAKQSGLY 457
Cdd:cd01319 226 vYKKSGIVNSFQEMLENIFEPLFEATKDPS--SHPELHVFLQQVIGFDSVDDESKSERRFTRKFPKPEEWTSEENPPYSY 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 458 YMYYLYANLAVLNSLRRRKGLEPLQLRCTGNKPTGMDDLIGAYILSDVITRATKITDYPVLQYLCGLHRVGLTVSPLCDH 537
Cdd:cd01319 304 YLYYMYANITTLNSFRKARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNN 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 538 MEgIVAYKDHPLPHFLHRCLHITLSTESPLRYHHNPRALIEEYATAQKMFRLSSLDMTELAHNSVLMSSFSPEVKRQWLG 617
Cdd:cd01319 384 SL-FLSYEKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLG 462
|
490 500 510
....*....|....*....|....*....|....
gi 323364103 618 DKYQL-GVEGNEFELSHVTNARLAFRDEAWQLER 650
Cdd:cd01319 463 PNYLKrGVAGNDIRRTNVPQIRMAYRYETLCEEL 496
|
|
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
127-655 |
1.40e-73 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 258.54 E-value: 1.40e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 127 KDGVYQVSDHDASL--FLPIPTWSQYATDVQKVRLTVGNAGCVNACHHRLGIMQERSRMFFLLNAGME---ERANYHKAg 201
Cdd:pfam19326 93 QDGVVHVYANKDALedSLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFNLHLMLNEMKElkaQKSNPHRD- 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 202 gvFSAARKVDNAVLLSESMDAQELLEGVKEMYRRSPEAAVHLRNGSNSTLRELLGAHGVrSADDLTVAGLGWQAEKDAPH 281
Cdd:pfam19326 172 --FYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKL-TGYDLSVDTLDVHADRDTFH 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 282 QgqIDLADCESMAALGAELRFSFTELQGYLCEKVLRRVVSR--AERPSLTPQAAEYSVPLYGLQSSELSYLAE-LMQRRL 358
Cdd:pfam19326 249 R--FDKFNLKYNPIGESRLREIFLKTDNYINGRYLAEITKEvfSDLEESKYQMAEYRISIYGRSPDEWDKLASwIVDNKV 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 359 EGPHPR----VQYILSIcftesppFEVVSSCTTLQDQLDNIFLALFKATLAPEDPSNAGVawLLGQVGGLQMLHAQDGPG 434
Cdd:pfam19326 327 YSPNVRwliqVPRLYDI-------YKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHV--FLKRVIGFDSVDDESKPE 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 435 RDFDEMAPPPDQVKIGAKQSGLYYMYYLYANLAVLNSLRRRKGLEPLQLRCTGNKPTGMDDLIGAYILSDVITRATKITD 514
Cdd:pfam19326 398 RRMFRKSPKPALWTNEQNPPYSYYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGISHGILLRK 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 515 YPVLQYLCGLHRVGLTVSPLCDHmEGIVAYKDHPLPHFLHRCLHITLSTESPLRYHHNPRALIEEYATAQKMFRLSSLDM 594
Cdd:pfam19326 478 SPVLQYLYYLAQIGIAMSPLSNN-SLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSACDM 556
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 323364103 595 TELAHNSVLMSSFSPEVKRQWLGDKY-QLGVEGNEFELSHVTNARLAFRDEAWQLERNMMRD 655
Cdd:pfam19326 557 CELARNSVLQSGFSHQLKSHWLGKDYyKEGPEGNDIRRTNVPDIRVAYRYETLCQELALISD 618
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
129-645 |
4.51e-70 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 247.83 E-value: 4.51e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 129 GVYQVSDHDASL------FLPIPTWSQYATDVQKVRLTVGNAGCVNACHHRLGIMQERSRMFFLLNAGME---ERANYHK 199
Cdd:TIGR01429 85 GVLFVYDNDTMLerqephFLVPPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSElkeQKSVPHR 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 200 AggvFSAARKVDNAVLLSESMDAQELLEGVKEMYRRSPEAAVHLRNGSNSTLRELLGAHGVrSADDLTVAGLGWQAEKDA 279
Cdd:TIGR01429 165 D---FYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHL-DPYDLSVDTLDVHADRNT 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 280 PHQgqIDLADCESMAALGAELRFSFTELQGYLCEKVLRRVVSR--AERPSLTPQAAEYSVPLYGLQSSELSYLAE-LMQR 356
Cdd:TIGR01429 241 FHR--FDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEvfTDLEDSKYQYAEPRLSIYGRSPKEWDSLARwIIDH 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 357 RLEGPHPR----VQYILSIcftesppFEVVSSCTTLQDQLDNIFLALFKATLAPEDPSNAGVawLLGQVGGLQMLHAQDG 432
Cdd:TIGR01429 319 DVFSPNVRwliqVPRLYDV-------YRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHL--FLQQVTGFDSVDDESK 389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 433 P-GRDFDEMAPPPDQVKIGAKQSGLYYMYYLYANLAVLNSLRRRKGLEPLQLRCTGNKPTGMDDLIGAYILSDVITRATK 511
Cdd:TIGR01429 390 HeDHMFSRKFPSPDEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGIL 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 512 ITDYPVLQYLCGLHRVGLTVSPLCDHmEGIVAYKDHPLPHFLHRCLHITLSTESPLRYHHNPRALIEEYATAQKMFRLSS 591
Cdd:TIGR01429 470 LRKVPVLQYLYYLTQIPIAMSPLSNN-SLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLST 548
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 323364103 592 LDMTELAHNSVLMSSFSPEVKRQWLGDKYQ-LGVEGNEFELSHVTNARLAFRDEA 645
Cdd:TIGR01429 549 CDMCELARNSVLQSGFEHQVKQHWLGPNYYkEGPEGNDIRRTNVPDIRVAFRYET 603
|
|
| PLN03055 |
PLN03055 |
AMP deaminase; Provisional |
90-654 |
4.28e-67 |
|
AMP deaminase; Provisional
Pssm-ID: 178613 Cd Length: 602 Bit Score: 239.00 E-value: 4.28e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 90 ALRVRSLYRPL------ETRVGGRERANP---YMSAPMPGRITIVQKDGVYQVSDHDA--SLFLPIPTWSQYATDVQKVr 158
Cdd:PLN03055 20 ELRDKYLFREKlppwrkGIFESSTSKPNPdpfRYEPEPPSQHVFRMVDGVMHVYAPDDakEELFPVPDATTFFTDMHRI- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 159 LTVGNAGCVNA-CHHRLGIMQERSRMFFLLNAGMEERANYHKAGGVFSAARKVDNAVLLSESMDAQELLEGVKEMYRRSP 237
Cdd:PLN03055 99 LRIVSLGNVRTfCHHRLKLLEQKFSLHLMLNADREFLAQKSAPHRDFYNVRKVDTHVHHSSCMNQKHLLRFIKSKLRKEP 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 238 EAAVHLRNGSNSTLRELLGAHGVrSADDLTVAGLGWQAEKDAPHQgqIDLADCESMAALGAELRFSFTE----LQGYLCE 313
Cdd:PLN03055 179 DEVVIFRDGKYLTLREVFESLDL-TGYDLNVDLLDVHADKNTFHR--FDKFNLKYNPCGQSRLREIFLKqdnlIQGRFLA 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 314 KVLRRVVSRAERPSLtpQAAEYSVPLYGLQSSELSYLAE-LMQRRLEGPH-------PRVQYIlsicftesppFEVVSSC 385
Cdd:PLN03055 256 ELTKEVFSDLEASKY--QMAEYRISIYGRKQSEWDQLASwIVNNRLYSENvvwliqlPRLYNV----------YKEMGIV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 386 TTLQDQLDNIFLALFKATLAPEdpSNAGVAWLLGQVGGLQMLHAQDGPGRDFDEMAPPPDQVKIGAKQSGLYYMYYLYAN 465
Cdd:PLN03055 324 QSFQQILDNIFKPLFEVTVDPS--SHPQLHVFLKMVVGFDMVDDESKPERRPTKHMQTPEQWDIPFNPAYSYWAYYVYAN 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 466 LAVLNSLRRRKGLEPLQLRCTGNKPTGMDDLIGAYILSDVITRATKITDYPVLQYLCGLHRVGLTVSPLCDHmEGIVAYK 545
Cdd:PLN03055 402 LYTLNKLRESKGLNTIKFRPHAGEAGDIDHLAAAFLLAHNIAHGNNLRKSPGLQYLYYLAQIGLAMSPLSNN-SLFLDYH 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 546 DHPLPHFLHRCLHITLSTESPLRYHHNPRALIEEYATAQKMFRLSSLDMTELAHNSVLMSSFSPEVKRQWLGDKYQL-GV 624
Cdd:PLN03055 481 RNPFPMFFARGLNVSLSTDDPLQIHLTKEPLVEEYSIAAQVWKLSSCDLCEIARNSVLQSGFPHASKKHWVGDNYWLrGP 560
|
570 580 590
....*....|....*....|....*....|
gi 323364103 625 EGNEFELSHVTNARLAFRDEAWQLERNMMR 654
Cdd:PLN03055 561 AGNDIHKTNVPHMRVEFRHEVWKEELQYVF 590
|
|
| PLN02768 |
PLN02768 |
AMP deaminase |
128-649 |
7.06e-60 |
|
AMP deaminase
Pssm-ID: 215411 Cd Length: 835 Bit Score: 222.43 E-value: 7.06e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 128 DGVYQV---SDHDASLFlPIPTWSQYATDVQKVrLTVGNAGCVNA-CHHRLGIMQERSRMFFLLNAGMEERANYHKAGGV 203
Cdd:PLN02768 300 DGVVHVyanKDSKEELF-PVADATTFFTDLHHI-LRVIAAGNIRTlCHHRLNLLEQKFNLHLMLNADREFLAQKSAPHRD 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 204 FSAARKVDNAVLLSESMDAQELLEGVKEMYRRSPEAAVHLRNGSNSTLRELLgahgvRSAD----DLTVAGLGWQAEKDA 279
Cdd:PLN02768 378 FYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLKEVF-----ESLDltgyDLNVDLLDVHADKST 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 280 PHQgqIDLADCESMAALGAELRFSFTE----LQGYLCEKVLRRVVSRAERPSLtpQAAEYSVPLYGLQSSELSYLAE-LM 354
Cdd:PLN02768 453 FHR--FDKFNLKYNPCGQSRLREIFLKqdnlIQGRFLAELTKQVFSDLEASKY--QMAEYRISIYGRKQSEWDQLASwIV 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 355 QRRLEGPH-------PRVQYIlsicftesppFEVVSSCTTLQDQLDNIFLALFKATLAPEdpSNAGVAWLLGQVGGLQML 427
Cdd:PLN02768 529 NNELYSENvvwliqlPRLYNV----------YKEMGIVTSFQNILDNIFIPLFEVTVDPD--SHPQLHVFLKQVVGLDLV 596
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 428 HAQDGPGRDFDEMAPPPDQVKIGAKQSGLYYMYYLYANLAVLNSLRRRKGLEPLQLRCTGNKPTGMDDLIGAYILSDVIT 507
Cdd:PLN02768 597 DDESKPERRPTKHMPTPAQWTNVFNPAFSYYVYYCYANLYTLNKLRESKGMTTIKFRPHSGEAGDIDHLAATFLTCHNIA 676
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 508 RATKITDYPVLQYLCGLHRVGLTVSPLCDHmEGIVAYKDHPLPHFLHRCLHITLSTESPLRYHHNPRALIEEYATAQKMF 587
Cdd:PLN02768 677 HGINLRKSPVLQYLYYLAQIGLAMSPLSNN-SLFLDYHRNPFPMFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVW 755
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 323364103 588 RLSSLDMTELAHNSVLMSSFSPEVKRQWLGDKY-QLGVEGNEFELSHVTNARLAFRDEAWQLE 649
Cdd:PLN02768 756 KLSSCDLCEIARNSVYQSGFSHALKSHWIGKEYyKRGPDGNDIHKTNVPHIRVEFRDTIWKEE 818
|
|
| ADA_AMPD |
cd00443 |
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic ... |
846-1236 |
1.33e-41 |
|
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic organisms and catalyze the zinc dependent irreversible deamination of adenosine nucleosides to inosine nucleosides and ammonia. The eukaryotic AMP deaminase catalyzes a similar reaction leading to the hydrolytic removal of an amino group at the 6 position of the adenine nucleotide ring, a branch point in the adenylate catabolic pathway.
Pssm-ID: 238250 Cd Length: 305 Bit Score: 155.58 E-value: 1.33e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 846 KVDTHIHMAAGMTPKQILKFVLAKLKEsgddiamkkgddiftlgqlfakagitpnltvdqlnvqadhtLFERFDNFnsky 925
Cdd:cd00443 3 KVELHAHLSGSISPETLLELIKKEFFE-----------------------------------------KFLLVHNL---- 37
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 926 npmengdlrslllktdnFMNGRYFAELIHDVFEQYSRDRYTYAENRLSVYGINV-KEWDKLAHWFATHGM--ANKHNKWI 1002
Cdd:cd00443 38 -----------------LQKGEALARALKEVIEEFAEDNVQYLELRTTPRLLETeKGLTKEQYWLLVIEGisEAKQWFPP 100
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1003 IQVPRVYKVFRAQNvigsfgqYLQNifqplweaSLHPSEHPTLHNFL-NHVSGFDSVDNEATIDLPFTTVSPwawtvven 1081
Cdd:cd00443 101 IKVRLILSVDRRGP-------YVQN--------YLVASEILELAKFLsNYVVGIDLVGDESKGENPLRDFYS-------- 157
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1082 ppynyylyylyanirtlnEFRASRGFSTFGLRPHCGESGSEVHLYGAF-LCANSICHGINLRNDPPMQYLYYLAQIGLHV 1160
Cdd:cd00443 158 ------------------YYEYARRLGLLGLTLHCGETGNREELLQALlLLPDRIGHGIFLLKHPELIYLVKLRNIPIEV 219
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 323364103 1161 SPLSNNALFL--HFLSNPFPDFFHRGLNVSLSTDDPMMFHQtqePLIEEYSIAARVWGLSANDLCEIARNSVLQCGFD 1236
Cdd:cd00443 220 CPTSNVVLGTvqSYEKHPFMRFFKAGLPVSLSTDDPGIFGT---SLSEEYSLAAKTFGLTFEDLCELNRNSVLSSFAK 294
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
1111-1230 |
1.29e-17 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 85.91 E-value: 1.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1111 GLR--PHCGESGSEVHLYGA--FLCANSICHGINLRNDPP-MQYLyylA--QIGLHVSPLSNNAL--FLHFLSNPFPDFF 1181
Cdd:COG1816 181 GLHltAHAGEAGGPESIWEAldLLGAERIGHGVRAIEDPAlVARL---AdrGIPLEVCPTSNVQLgvVPSLAEHPLRRLL 257
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 323364103 1182 HRGLNVSLSTDDPMMFHQTqepLIEEYSIAARVWGLSANDLCEIARNSV 1230
Cdd:COG1816 258 DAGVRVTLNTDDPLYFGTT---LTDEYELAAEAFGLSDADLAQLARNAI 303
|
|
| PRK09358 |
PRK09358 |
adenosine deaminase; Provisional |
1111-1230 |
5.73e-16 |
|
adenosine deaminase; Provisional
Pssm-ID: 236480 Cd Length: 340 Bit Score: 80.99 E-value: 5.73e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1111 GLR--PHCGESGSEVHLYGA--FLCANSICHGINLRNDPpmQYLYYLA--QIGLHVSPLSNNAL--FLHFLSNPFPDFFH 1182
Cdd:PRK09358 195 GLRltAHAGEAGGPESIWEAldELGAERIGHGVRAIEDP--ALMARLAdrRIPLEVCPTSNVQTgaVPSLAEHPLKTLLD 272
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 323364103 1183 RGLNVSLSTDDPMMFHQTqepLIEEYSIAARVWGLSANDLCEIARNSV 1230
Cdd:PRK09358 273 AGVRVTINTDDPLVFGTT---LTEEYEALAEAFGLSDEDLAQLARNAL 317
|
|
| ADA |
cd01320 |
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the ... |
1111-1230 |
1.07e-15 |
|
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.
Pssm-ID: 238645 Cd Length: 325 Bit Score: 79.94 E-value: 1.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1111 GLR--PHCGESGSEVHLYGAF--LCANSICHGINLRNDPpmqYLY-YLA--QIGLHVSPLSNNAL--FLHFLSNPFPDFF 1181
Cdd:cd01320 186 GLRltAHAGEAGGPESVRDALdlLGAERIGHGIRAIEDP---ELVkRLAerNIPLEVCPTSNVQTgaVKSLAEHPLRELL 262
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 323364103 1182 HRGLNVSLSTDDPMMFHQTqepLIEEYSIAARVWGLSANDLCEIARNSV 1230
Cdd:cd01320 263 DAGVKVTINTDDPTVFGTY---LTDEYELLAEAFGLTEEELKKLARNAV 308
|
|
| ADA_AMPD |
cd00443 |
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic ... |
457-617 |
1.10e-14 |
|
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic organisms and catalyze the zinc dependent irreversible deamination of adenosine nucleosides to inosine nucleosides and ammonia. The eukaryotic AMP deaminase catalyzes a similar reaction leading to the hydrolytic removal of an amino group at the 6 position of the adenine nucleotide ring, a branch point in the adenylate catabolic pathway.
Pssm-ID: 238250 Cd Length: 305 Bit Score: 76.62 E-value: 1.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 457 YYMYYLYAnlavlnslrRRKGLEPLQLRCtGNKPTGMDDLIGAYILSDVITRATKITDYPVLQYLCGLHRVGLTVSPLCD 536
Cdd:cd00443 155 FYSYYEYA---------RRLGLLGLTLHC-GETGNREELLQALLLLPDRIGHGIFLLKHPELIYLVKLRNIPIEVCPTSN 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 537 HMEGIV-AYKDHPLPHFLHRCLHITLSTESPLrYHHNPraLIEEYATAQKMFRLSSLDMTELAHNSVLMSSFSPEVKRQW 615
Cdd:cd00443 225 VVLGTVqSYEKHPFMRFFKAGLPVSLSTDDPG-IFGTS--LSEEYSLAAKTFGLTFEDLCELNRNSVLSSFAKDEEKKSL 301
|
..
gi 323364103 616 LG 617
Cdd:cd00443 302 LE 303
|
|
| A_deaminase |
pfam00962 |
Adenosine deaminase; |
1114-1230 |
1.94e-11 |
|
Adenosine deaminase;
Pssm-ID: 425964 Cd Length: 330 Bit Score: 67.07 E-value: 1.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1114 PHCGESGS--EVHLYGAFLCANSICHGINLRNDPPMqyLYYLA--QIGLHVSPLSNNAL--FLHFLSNPFPDFFHRGLNV 1187
Cdd:pfam00962 193 VHAGEAGGpqSVWEALDDLGAERIGHGVRSAEDPRL--LDRLAdrQIPLEICPTSNVQTgaVASLAEHPLKTFLRAGVPV 270
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 323364103 1188 SLSTDDPMMFHQTqepLIEEYSIAARVWGLSANDLCEIARNSV 1230
Cdd:pfam00962 271 SLNTDDPLMFGSD---LLDEYQVAKRAPGFDEEELARLAKNAV 310
|
|
| PRK09358 |
PRK09358 |
adenosine deaminase; Provisional |
525-618 |
5.64e-08 |
|
adenosine deaminase; Provisional
Pssm-ID: 236480 Cd Length: 340 Bit Score: 56.34 E-value: 5.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 525 HRVGLTVSPLCDHMEGIVA-YKDHPLPHFLHRCLHITLSTESPLRYHHNpraLIEEYATAQKMFRLSSLDMTELAHNSVL 603
Cdd:PRK09358 242 RRIPLEVCPTSNVQTGAVPsLAEHPLKTLLDAGVRVTINTDDPLVFGTT---LTEEYEALAEAFGLSDEDLAQLARNALE 318
|
90
....*....|....*
gi 323364103 604 MSSFSPEVKRQWLGD 618
Cdd:PRK09358 319 AAFLSEEEKAALLAE 333
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
525-616 |
3.06e-07 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 53.94 E-value: 3.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 525 HRVGLTVSPLCDHMEGIVA-YKDHPLPHFLHRCLHITLSTESPLrYHHNPraLIEEYATAQKMFRLSSLDMTELAHNSVL 603
Cdd:COG1816 228 RGIPLEVCPTSNVQLGVVPsLAEHPLRRLLDAGVRVTLNTDDPL-YFGTT--LTDEYELAAEAFGLSDADLAQLARNAIE 304
|
90
....*....|...
gi 323364103 604 MSSFSPEVKRQWL 616
Cdd:COG1816 305 ASFLPEEEKAALL 317
|
|
| ADA |
cd01320 |
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the ... |
526-616 |
6.80e-07 |
|
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.
Pssm-ID: 238645 Cd Length: 325 Bit Score: 52.98 E-value: 6.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 526 RVGLTVSPLCDHMEGIVA-YKDHPLPHFLHRCLHITLSTESPLRYHHNpraLIEEYATAQKMFRLSSLDMTELAHNSVLM 604
Cdd:cd01320 234 NIPLEVCPTSNVQTGAVKsLAEHPLRELLDAGVKVTINTDDPTVFGTY---LTDEYELLAEAFGLTEEELKKLARNAVEA 310
|
90
....*....|..
gi 323364103 605 SSFSPEVKRQWL 616
Cdd:cd01320 311 SFLSEEEKAELL 322
|
|
| metallo-dependent_hydrolases |
cd01292 |
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a ... |
1112-1226 |
5.38e-05 |
|
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The family includes urease alpha, adenosine deaminase, phosphotriesterase dihydroorotases, allantoinases, hydantoinases, AMP-, adenine and cytosine deaminases, imidazolonepropionase, aryldialkylphosphatase, chlorohydrolases, formylmethanofuran dehydrogenases and others.
Pssm-ID: 238617 [Multi-domain] Cd Length: 275 Bit Score: 46.94 E-value: 5.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1112 LRPHCGESGSEVHLYGAFLCAN------SICHGINLrnDPPMQYLYYLAQIGLHVSPLSNNALFL-HFLSNPFPDFFHRG 1184
Cdd:cd01292 149 VVIHAGELPDPTRALEDLVALLrlggrvVIGHVSHL--DPELLELLKEAGVSLEVCPLSNYLLGRdGEGAEALRRLLELG 226
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 323364103 1185 LNVSLSTDDPmmFHQTQEPLIEEYSIAARVW--GLSANDLCEIA 1226
Cdd:cd01292 227 IRVTLGTDGP--PHPLGTDLLALLRLLLKVLrlGLSLEEALRLA 268
|
|
| PTZ00124 |
PTZ00124 |
adenosine deaminase; Provisional |
1114-1197 |
6.75e-03 |
|
adenosine deaminase; Provisional
Pssm-ID: 173415 Cd Length: 362 Bit Score: 40.62 E-value: 6.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323364103 1114 PHCGESGSEVHLYGAflcaNSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNAL--FLHFLSNPFPDFFHRGLNVSLST 1191
Cdd:PTZ00124 233 PNLNTLYSAIQVLKV----KRIGHGIRVAESQELIDMVKEKDILLEVCPISNVLLnnAKSMDTHPIRKLYDAGVKVSVNS 308
|
....*.
gi 323364103 1192 DDPMMF 1197
Cdd:PTZ00124 309 DDPGMF 314
|
|
| |
