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Conserved domains on  [gi|3298472|dbj|BAA31522|]
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zinc finger protein [Mus musculus]

Protein Classification

AKAP95 family protein( domain architecture ID 10523253)

AKAP95 (A-kinase anchoring protein 95) family protein similar to human DBIRD complex subunit ZNF326, a core component of the DBIRD complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AKAP95 pfam04988
A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is ...
 337-472 9.60e-79

A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.


:

Pssm-ID: 461509  Cd Length: 136  Bit Score: 244.31  E-value: 9.60e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3298472    337 QETLDHIQKQTKFDKVVMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDIMEGVTADDHMMKVETVHCSACSVYIPA 416
Cdd:pfam04988   1 KETLDYIQKQTKFDKVVMEFLHECMVNKFKKTEERRQQLNDLESVKKQIEKDVMEGVTEEDFMKKVEAAHCAACDLLIPA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 3298472    417 LHSSVQLHLKSPDHSKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPF 472
Cdd:pfam04988  81 QFSSVQQHLKSADHNKNKRLYKEQSKKESLLTATSILNNPHIKARYEKYIKGENPF 136
 
Name Accession Description Interval E-value
AKAP95 pfam04988
A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is ...
 337-472 9.60e-79

A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.


Pssm-ID: 461509  Cd Length: 136  Bit Score: 244.31  E-value: 9.60e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3298472    337 QETLDHIQKQTKFDKVVMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDIMEGVTADDHMMKVETVHCSACSVYIPA 416
Cdd:pfam04988   1 KETLDYIQKQTKFDKVVMEFLHECMVNKFKKTEERRQQLNDLESVKKQIEKDVMEGVTEEDFMKKVEAAHCAACDLLIPA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 3298472    417 LHSSVQLHLKSPDHSKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPF 472
Cdd:pfam04988  81 QFSSVQQHLKSADHNKNKRLYKEQSKKESLLTATSILNNPHIKARYEKYIKGENPF 136
 
Name Accession Description Interval E-value
AKAP95 pfam04988
A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is ...
 337-472 9.60e-79

A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.


Pssm-ID: 461509  Cd Length: 136  Bit Score: 244.31  E-value: 9.60e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3298472    337 QETLDHIQKQTKFDKVVMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDIMEGVTADDHMMKVETVHCSACSVYIPA 416
Cdd:pfam04988   1 KETLDYIQKQTKFDKVVMEFLHECMVNKFKKTEERRQQLNDLESVKKQIEKDVMEGVTEEDFMKKVEAAHCAACDLLIPA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 3298472    417 LHSSVQLHLKSPDHSKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPF 472
Cdd:pfam04988  81 QFSSVQQHLKSADHNKNKRLYKEQSKKESLLTATSILNNPHIKARYEKYIKGENPF 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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