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Conserved domains on  [gi|402585077|gb|EJW79017|]
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hypothetical protein WUBG_10073 [Wuchereria bancrofti]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PDEase_I_N super family cl07209
3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of ...
 58-115 2.44e-23

3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of the calcium/calmodulin-dependent 3'5'-cyclic nucleotide phosphodiesterase domain (pfam00233).


The actual alignment was detected with superfamily member pfam08499:

Pssm-ID: 462497 [Multi-domain]  Cd Length: 61  Bit Score: 89.71  E-value: 2.44e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 402585077   58 RICDEEDDLADVKPEAVSDEVRKWLAATFTKQSVLSKR---EKPKLKSVANAILTGIFFDK 115
Cdd:pfam08499   1 RLLDEEDELSEIQSDAVPSEVRDWLASTFTRQMAAHKRrseEKPKFRSVAHAVQAGIFVER 61
PDEase_I super family cl47516
3'5'-cyclic nucleotide phosphodiesterase;
199-256 1.85e-18

3'5'-cyclic nucleotide phosphodiesterase;


The actual alignment was detected with superfamily member pfam00233:

Pssm-ID: 459723  Cd Length: 238  Bit Score: 81.44  E-value: 1.85e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 402585077  199 YHNVVHAADVTASSHFMLSQTGFATSLSDLDILAVIFGAMIHDYQHTGHTNNFHIQTG 256
Cdd:pfam00233   1 YHNWRHAFDVTQTMYYLLKTGKLKEVLTDLEILALLIAALCHDVDHPGTNNAFLIKTK 58
 
Name Accession Description Interval E-value
PDEase_I_N pfam08499
3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of ...
 58-115 2.44e-23

3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of the calcium/calmodulin-dependent 3'5'-cyclic nucleotide phosphodiesterase domain (pfam00233).


Pssm-ID: 462497 [Multi-domain]  Cd Length: 61  Bit Score: 89.71  E-value: 2.44e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 402585077   58 RICDEEDDLADVKPEAVSDEVRKWLAATFTKQSVLSKR---EKPKLKSVANAILTGIFFDK 115
Cdd:pfam08499   1 RLLDEEDELSEIQSDAVPSEVRDWLASTFTRQMAAHKRrseEKPKFRSVAHAVQAGIFVER 61
PDEase_I pfam00233
3'5'-cyclic nucleotide phosphodiesterase;
199-256 1.85e-18

3'5'-cyclic nucleotide phosphodiesterase;


Pssm-ID: 459723  Cd Length: 238  Bit Score: 81.44  E-value: 1.85e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 402585077  199 YHNVVHAADVTASSHFMLSQTGFATSLSDLDILAVIFGAMIHDYQHTGHTNNFHIQTG 256
Cdd:pfam00233   1 YHNWRHAFDVTQTMYYLLKTGKLKEVLTDLEILALLIAALCHDVDHPGTNNAFLIKTK 58
HDc smart00471
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic ...
 197-256 4.60e-03

Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic nucleotide phosphodiesterases (PDEc). This profile/HMM does not detect HD homologues in bacterial glycine aminoacyl-tRNA synthetases (beta subunit).


Pssm-ID: 214679 [Multi-domain]  Cd Length: 124  Bit Score: 36.12  E-value: 4.60e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 402585077   197 NPYHNVVHAADVTASSHFMlsqtgfATSLSDLDILAVIFGAMIHDYQHTGHTNNFHIQTG 256
Cdd:smart00471   1 SDYHVFEHSLRVAQLAAAL------AEELGLLDIELLLLAALLHDIGKPGTPDSFLVKTS 54
 
Name Accession Description Interval E-value
PDEase_I_N pfam08499
3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of ...
 58-115 2.44e-23

3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of the calcium/calmodulin-dependent 3'5'-cyclic nucleotide phosphodiesterase domain (pfam00233).


Pssm-ID: 462497 [Multi-domain]  Cd Length: 61  Bit Score: 89.71  E-value: 2.44e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 402585077   58 RICDEEDDLADVKPEAVSDEVRKWLAATFTKQSVLSKR---EKPKLKSVANAILTGIFFDK 115
Cdd:pfam08499   1 RLLDEEDELSEIQSDAVPSEVRDWLASTFTRQMAAHKRrseEKPKFRSVAHAVQAGIFVER 61
PDEase_I pfam00233
3'5'-cyclic nucleotide phosphodiesterase;
199-256 1.85e-18

3'5'-cyclic nucleotide phosphodiesterase;


Pssm-ID: 459723  Cd Length: 238  Bit Score: 81.44  E-value: 1.85e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 402585077  199 YHNVVHAADVTASSHFMLSQTGFATSLSDLDILAVIFGAMIHDYQHTGHTNNFHIQTG 256
Cdd:pfam00233   1 YHNWRHAFDVTQTMYYLLKTGKLKEVLTDLEILALLIAALCHDVDHPGTNNAFLIKTK 58
HDc smart00471
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic ...
 197-256 4.60e-03

Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic nucleotide phosphodiesterases (PDEc). This profile/HMM does not detect HD homologues in bacterial glycine aminoacyl-tRNA synthetases (beta subunit).


Pssm-ID: 214679 [Multi-domain]  Cd Length: 124  Bit Score: 36.12  E-value: 4.60e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 402585077   197 NPYHNVVHAADVTASSHFMlsqtgfATSLSDLDILAVIFGAMIHDYQHTGHTNNFHIQTG 256
Cdd:smart00471   1 SDYHVFEHSLRVAQLAAAL------AEELGLLDIELLLLAALLHDIGKPGTPDSFLVKTS 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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