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Conserved domains on  [gi|476067359|gb|EMU91867|]
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putative cS6 fimbrial subunit B [Escherichia coli MP021017.3]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CssAB pfam16831
CS6 fimbrial subunits A and B, Coli surface antigen 6; CssAB is a family of CS6 pilins from E. ...
 39-167 3.50e-91

CS6 fimbrial subunits A and B, Coli surface antigen 6; CssAB is a family of CS6 pilins from E.coli, including both subunits A and B. It acts as a colonization factor for the enterotoxigenic species pf E.coli to mediate bacterial attachment to the small intestinal epithelium. Both subunits in the fibre bind to receptors on epithelial cells, and that CssB, but not CssA, specifically recognizes the extracellular matrix protein fibronectin.


:

Pssm-ID: 318930  Cd Length: 129  Bit Score: 261.27  E-value: 3.50e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476067359   39 FIPDIDSAVRIIPVNYDSDPKLNSQLYTVEMTIPAGVSAVKIVPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGK 118
Cdd:pfam16831   1 FIPDIDSAVRIIPVNYDSDPKLNSQLYTVEMTIPAGVSAVKIVPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGK 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 476067359  119 FMAGQKGSFSVKENTSYTFSAIYTGGEYPNSGYSSGTYAGHLTVSFYSN 167
Cdd:pfam16831  81 FMAGQKGSFSVKENTSYTFSAIYTGGEYPNSGYSSGTYAGHLTVSFYSN 129
 
Name Accession Description Interval E-value
CssAB pfam16831
CS6 fimbrial subunits A and B, Coli surface antigen 6; CssAB is a family of CS6 pilins from E. ...
 39-167 3.50e-91

CS6 fimbrial subunits A and B, Coli surface antigen 6; CssAB is a family of CS6 pilins from E.coli, including both subunits A and B. It acts as a colonization factor for the enterotoxigenic species pf E.coli to mediate bacterial attachment to the small intestinal epithelium. Both subunits in the fibre bind to receptors on epithelial cells, and that CssB, but not CssA, specifically recognizes the extracellular matrix protein fibronectin.


Pssm-ID: 318930  Cd Length: 129  Bit Score: 261.27  E-value: 3.50e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476067359   39 FIPDIDSAVRIIPVNYDSDPKLNSQLYTVEMTIPAGVSAVKIVPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGK 118
Cdd:pfam16831   1 FIPDIDSAVRIIPVNYDSDPKLNSQLYTVEMTIPAGVSAVKIVPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGK 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 476067359  119 FMAGQKGSFSVKENTSYTFSAIYTGGEYPNSGYSSGTYAGHLTVSFYSN 167
Cdd:pfam16831  81 FMAGQKGSFSVKENTSYTFSAIYTGGEYPNSGYSSGTYAGHLTVSFYSN 129
 
Name Accession Description Interval E-value
CssAB pfam16831
CS6 fimbrial subunits A and B, Coli surface antigen 6; CssAB is a family of CS6 pilins from E. ...
 39-167 3.50e-91

CS6 fimbrial subunits A and B, Coli surface antigen 6; CssAB is a family of CS6 pilins from E.coli, including both subunits A and B. It acts as a colonization factor for the enterotoxigenic species pf E.coli to mediate bacterial attachment to the small intestinal epithelium. Both subunits in the fibre bind to receptors on epithelial cells, and that CssB, but not CssA, specifically recognizes the extracellular matrix protein fibronectin.


Pssm-ID: 318930  Cd Length: 129  Bit Score: 261.27  E-value: 3.50e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476067359   39 FIPDIDSAVRIIPVNYDSDPKLNSQLYTVEMTIPAGVSAVKIVPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGK 118
Cdd:pfam16831   1 FIPDIDSAVRIIPVNYDSDPKLNSQLYTVEMTIPAGVSAVKIVPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGK 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 476067359  119 FMAGQKGSFSVKENTSYTFSAIYTGGEYPNSGYSSGTYAGHLTVSFYSN 167
Cdd:pfam16831  81 FMAGQKGSFSVKENTSYTFSAIYTGGEYPNSGYSSGTYAGHLTVSFYSN 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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