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Conserved domains on  [gi|488215644|ref|WP_002286852|]
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MULTISPECIES: AraC family transcriptional regulator [Enterococcus]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 14401244)

AraC family transcriptional regulator containing an AraC family helix-turn-helix (HTH) DNA-binding domain and a cupin-like effector domain, controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
cupin_MmsR-like_N cd06986
AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain; This ...
 16-97 1.85e-37

AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain; This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included is MmsR, a bacterial transcriptional regulator thought to positively regulate the expression of the mmsAB operon. The mmsAB operon contains two structural genes involved in valine metabolism: mmsA which encodes methylmalonate-semialdehyde dehydrogenase, and mmsB which encodes 3-hydroxyisobutyrate dehydrogenase. The cupin domain of members of this subfamily does not contain a metal binding site.


:

Pssm-ID: 380391 [Multi-domain]  Cd Length: 84  Bit Score: 127.99  E-value: 1.85e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  16 KELYFDFCGFSKTMPFHSFGPAIRNDYILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFG 95
Cdd:cd06986    3 SDLYLTDCGYEPCEPGHSYGPAVRDYYILHYVLSGKGTFSVNGKTYHLKAGQGFLIPPGEPHSYGADEDDPWTYYWIGFS 82


                 ..
gi 488215644  96 GS 97
Cdd:cd06986   83 GS 84
GlxA super family cl34854
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 167-273 2.15e-29

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


The actual alignment was detected with superfamily member COG4977:

Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 113.71  E-value: 2.15e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 167 QKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQ 246
Cdd:COG4977  205 LGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAA 284

                         90       100
                 ....*....|....*....|....*..
gi 488215644 247 VGFNSLVVFSRMFKKSTGETATNYRKR 273
Cdd:COG4977  285 CGFGSASHFRRAFRRRFGVSPSAYRRR 311
 
Name Accession Description Interval E-value
cupin_MmsR-like_N cd06986
AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain; This ...
 16-97 1.85e-37

AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain; This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included is MmsR, a bacterial transcriptional regulator thought to positively regulate the expression of the mmsAB operon. The mmsAB operon contains two structural genes involved in valine metabolism: mmsA which encodes methylmalonate-semialdehyde dehydrogenase, and mmsB which encodes 3-hydroxyisobutyrate dehydrogenase. The cupin domain of members of this subfamily does not contain a metal binding site.


Pssm-ID: 380391 [Multi-domain]  Cd Length: 84  Bit Score: 127.99  E-value: 1.85e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  16 KELYFDFCGFSKTMPFHSFGPAIRNDYILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFG 95
Cdd:cd06986    3 SDLYLTDCGYEPCEPGHSYGPAVRDYYILHYVLSGKGTFSVNGKTYHLKAGQGFLIPPGEPHSYGADEDDPWTYYWIGFS 82


                 ..
gi 488215644  96 GS 97
Cdd:cd06986   83 GS 84
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 167-273 2.15e-29

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 113.71  E-value: 2.15e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 167 QKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQ 246
Cdd:COG4977  205 LGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAA 284

                         90       100
                 ....*....|....*....|....*..
gi 488215644 247 VGFNSLVVFSRMFKKSTGETATNYRKR 273
Cdd:COG4977  285 CGFGSASHFRRAFRRRFGVSPSAYRRR 311
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
188-271 2.04e-26

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 99.16  E-value: 2.04e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644   188 KLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETA 267
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 488215644   268 TNYR 271
Cdd:smart00342  81 SEYR 84
AraC_binding pfam02311
AraC-like ligand binding domain; This family represents the arabinose-binding and dimerization ...
 19-152 4.40e-23

AraC-like ligand binding domain; This family represents the arabinose-binding and dimerization domain of the bacterial gene regulatory protein AraC. The domain is found in conjunction with the helix-turn-helix (HTH) DNA-binding motif pfam00165. This domain is distantly related to the Cupin domain pfam00190.


Pssm-ID: 396749 [Multi-domain]  Cd Length: 134  Bit Score: 92.11  E-value: 4.40e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644   19 YFDFCGFSKTMPFHSFGPAIRNDYILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSA 98
Cdd:pfam02311   1 NPGLEGIEARYPGHSFPPHVHDFYVIGYIERGVGRFRLNGRTYHLGPGDLFLLPPGEPHDYEPESEDGWRYRWLYFEPEL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 488215644   99 AEEIIR--QSLFREDQYTMVSSDIQKYIDIILECMkdTEETLENELQLTALTYRFL 152
Cdd:pfam02311  81 LERILAdiSILAGGPLPLLRDPELAALLRALFRLL--EEAGRSDDLLAEALLYQLL 134
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
42-273 5.25e-23

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 95.81  E-value: 5.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  42 YILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFY-LSDGEDPWMYCWLSFGGSA--AEEIIRQSLFREDQYTMVSS 118
Cdd:PRK10572  50 YILNLTIRGQGVIFNGGRAFVCRPGDLLLFPPGEIHHYgRHPDSDEWYHQWVYFRPRAywADWLNWPSIFAGVGRLRIPD 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 119 DiqKYIDIILECMKDTEETLEN------ELQLTALTYrflsVLLKDGGKVSGGVQKVHSSLAVETVKYIEAHYAEKLSVE 192
Cdd:PRK10572 130 E--ALQPEFSDLFGQIEQAGQSegryseLLAMNLLER----LLLRCMEAIPESLHPPMDPRVREACQYISDHLASEFDIE 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 193 EIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRK 272
Cdd:PRK10572 204 SVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFKKCTGASPSEFRA 283


                 .
gi 488215644 273 R 273
Cdd:PRK10572 284 R 284
HTH_18 pfam12833
Helix-turn-helix domain;
194-273 5.80e-23

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 89.96  E-value: 5.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  194 IAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRG-AFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRK 272
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERArRLLLEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 488215644  273 R 273
Cdd:pfam12833  81 R 81
PRK10371 PRK10371
transcriptional regulator MelR;
180-272 4.86e-16

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 76.78  E-value: 4.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 180 YIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMF 259
Cdd:PRK10371 199 FIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTF 278

                         90
                 ....*....|...
gi 488215644 260 KKSTGETATNYRK 272
Cdd:PRK10371 279 GKYVGMSPQQYRK 291
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 54-271 5.18e-14

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 71.63  E-value: 5.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644   54 YHVKNQQFQL-KKGDLFLIRpgDSTFYLSDGEDPwmycwlsfggsaaeeIIRQSLFR-EDQYTMVSSD------IQKYID 125
Cdd:TIGR04094 174 FHYENQILELvKKGDIQQLK--ELVFQLSNSVIP---------------IVSGDDLRsEKNYSIIIFEklsqlaIQMGVD 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  126 IIlECMKDTEETL-ENELQLTaltyrFLSVL-LKDGG------KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQH 197
Cdd:TIGR04094 237 IV-DAYRLRDYYIqEIEEQTS-----LMDVLkLRDSAiiyfteLLHEISINHHSPLIRAVIQYINLNLYDPLKVEEIAKQ 310

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488215644  198 LAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSlTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYR 271
Cdd:TIGR04094 311 FFMSESKLRKLFKKEMGISIQEYISKRKIEEAKYLLR-SQIPVSEVSNELGFYDLSHFSRTFKKHTGVSPKQYQ 383
 
Name Accession Description Interval E-value
cupin_MmsR-like_N cd06986
AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain; This ...
 16-97 1.85e-37

AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain; This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included is MmsR, a bacterial transcriptional regulator thought to positively regulate the expression of the mmsAB operon. The mmsAB operon contains two structural genes involved in valine metabolism: mmsA which encodes methylmalonate-semialdehyde dehydrogenase, and mmsB which encodes 3-hydroxyisobutyrate dehydrogenase. The cupin domain of members of this subfamily does not contain a metal binding site.


Pssm-ID: 380391 [Multi-domain]  Cd Length: 84  Bit Score: 127.99  E-value: 1.85e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  16 KELYFDFCGFSKTMPFHSFGPAIRNDYILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFG 95
Cdd:cd06986    3 SDLYLTDCGYEPCEPGHSYGPAVRDYYILHYVLSGKGTFSVNGKTYHLKAGQGFLIPPGEPHSYGADEDDPWTYYWIGFS 82


                 ..
gi 488215644  96 GS 97
Cdd:cd06986   83 GS 84
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 167-273 2.15e-29

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 113.71  E-value: 2.15e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 167 QKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQ 246
Cdd:COG4977  205 LGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAA 284

                         90       100
                 ....*....|....*....|....*..
gi 488215644 247 VGFNSLVVFSRMFKKSTGETATNYRKR 273
Cdd:COG4977  285 CGFGSASHFRRAFRRRFGVSPSAYRRR 311
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
181-278 1.93e-27

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 107.56  E-value: 1.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 181 IEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFK 260
Cdd:COG2207  161 LLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFK 240

                         90
                 ....*....|....*...
gi 488215644 261 KSTGETATNYRKRMKNEN 278
Cdd:COG2207  241 KRFGVTPSEYRKRLRARA 258
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
188-271 2.04e-26

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 99.16  E-value: 2.04e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644   188 KLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETA 267
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 488215644   268 TNYR 271
Cdd:smart00342  81 SEYR 84
AraC_binding pfam02311
AraC-like ligand binding domain; This family represents the arabinose-binding and dimerization ...
 19-152 4.40e-23

AraC-like ligand binding domain; This family represents the arabinose-binding and dimerization domain of the bacterial gene regulatory protein AraC. The domain is found in conjunction with the helix-turn-helix (HTH) DNA-binding motif pfam00165. This domain is distantly related to the Cupin domain pfam00190.


Pssm-ID: 396749 [Multi-domain]  Cd Length: 134  Bit Score: 92.11  E-value: 4.40e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644   19 YFDFCGFSKTMPFHSFGPAIRNDYILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSA 98
Cdd:pfam02311   1 NPGLEGIEARYPGHSFPPHVHDFYVIGYIERGVGRFRLNGRTYHLGPGDLFLLPPGEPHDYEPESEDGWRYRWLYFEPEL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 488215644   99 AEEIIR--QSLFREDQYTMVSSDIQKYIDIILECMkdTEETLENELQLTALTYRFL 152
Cdd:pfam02311  81 LERILAdiSILAGGPLPLLRDPELAALLRALFRLL--EEAGRSDDLLAEALLYQLL 134
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
42-273 5.25e-23

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 95.81  E-value: 5.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  42 YILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFY-LSDGEDPWMYCWLSFGGSA--AEEIIRQSLFREDQYTMVSS 118
Cdd:PRK10572  50 YILNLTIRGQGVIFNGGRAFVCRPGDLLLFPPGEIHHYgRHPDSDEWYHQWVYFRPRAywADWLNWPSIFAGVGRLRIPD 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 119 DiqKYIDIILECMKDTEETLEN------ELQLTALTYrflsVLLKDGGKVSGGVQKVHSSLAVETVKYIEAHYAEKLSVE 192
Cdd:PRK10572 130 E--ALQPEFSDLFGQIEQAGQSegryseLLAMNLLER----LLLRCMEAIPESLHPPMDPRVREACQYISDHLASEFDIE 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 193 EIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRK 272
Cdd:PRK10572 204 SVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFKKCTGASPSEFRA 283


                 .
gi 488215644 273 R 273
Cdd:PRK10572 284 R 284
HTH_18 pfam12833
Helix-turn-helix domain;
194-273 5.80e-23

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 89.96  E-value: 5.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  194 IAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRG-AFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRK 272
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERArRLLLEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 488215644  273 R 273
Cdd:pfam12833  81 R 81
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 170-273 6.87e-23

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 96.66  E-value: 6.87e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 170 HSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSlTDESVESIAYQVGF 249
Cdd:COG2169   82 RADLVARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLLQ-TGLSVTDAAYAAGF 160

                         90       100
                 ....*....|....*....|....
gi 488215644 250 NSLVVFSRMFKKSTGETATNYRKR 273
Cdd:COG2169  161 GSLSRFYEAFKKLLGMTPSAYRRG 184
PRK10371 PRK10371
transcriptional regulator MelR;
180-272 4.86e-16

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 76.78  E-value: 4.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 180 YIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMF 259
Cdd:PRK10371 199 FIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTF 278

                         90
                 ....*....|...
gi 488215644 260 KKSTGETATNYRK 272
Cdd:PRK10371 279 GKYVGMSPQQYRK 291
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 54-271 5.18e-14

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 71.63  E-value: 5.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644   54 YHVKNQQFQL-KKGDLFLIRpgDSTFYLSDGEDPwmycwlsfggsaaeeIIRQSLFR-EDQYTMVSSD------IQKYID 125
Cdd:TIGR04094 174 FHYENQILELvKKGDIQQLK--ELVFQLSNSVIP---------------IVSGDDLRsEKNYSIIIFEklsqlaIQMGVD 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  126 IIlECMKDTEETL-ENELQLTaltyrFLSVL-LKDGG------KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQH 197
Cdd:TIGR04094 237 IV-DAYRLRDYYIqEIEEQTS-----LMDVLkLRDSAiiyfteLLHEISINHHSPLIRAVIQYINLNLYDPLKVEEIAKQ 310

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488215644  198 LAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSlTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYR 271
Cdd:TIGR04094 311 FFMSESKLRKLFKKEMGISIQEYISKRKIEEAKYLLR-SQIPVSEVSNELGFYDLSHFSRTFKKHTGVSPKQYQ 383
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
170-274 1.14e-11

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 60.32  E-value: 1.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 170 HSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGF 249
Cdd:PRK10219   3 HQKIIQTLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGY 82

                         90       100
                 ....*....|....*....|....*
gi 488215644 250 NSLVVFSRMFKKSTGETATNYRKRM 274
Cdd:PRK10219  83 VSQQTFSRVFRRQFDRTPSDYRHRL 107
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
29-273 5.83e-10

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 59.15  E-value: 5.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  29 MPFHSFGPAIRNDYILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGE---DPWMYC---------WLSFGG 96
Cdd:PRK13501  26 YPQETFVEHTHQFCEIVIVWRGNGLHVLNDHPYRITCGDVFYIQAADHHSYESVHDlvlDNIIYCperlhlnaqWHKLLP 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  97 SAAEEIiRQSLFREDQYTMVSSDiqkyiDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG-------KVSGGVQK- 168
Cdd:PRK13501 106 PLGPEQ-NQGYWRLTTQGMAQAR-----PIIQQLAQESRKTDSWSIQLTEVLLLQLAIVLKRHRyraeqahLLPDGEQLd 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 169 -VHSSLAVETVKYIE-AHYAEklsveeiaQHLAVNRShLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQ 246
Cdd:PRK13501 180 lIMSALQQSLGAYFDmADFCH--------KNQLVERS-LKQLFRQQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAAR 250

                        250       260
                 ....*....|....*....|....*..
gi 488215644 247 VGFNSLVVFSRMFKKSTGETATNYRKR 273
Cdd:PRK13501 251 CGFEDSNYFSAVFTREAGMTPRDYRQR 277
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 181-221 8.90e-10

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 53.31  E-value: 8.90e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 488215644  181 IEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYL 221
Cdd:pfam00165   1 LRENLSTNLTIADIADELGFSRSYFSRLFKKYTGVTPSQYR 41
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
116-261 1.10e-09

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 58.15  E-value: 1.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 116 VSSDIQKYIDIILECMK--DTEETLENELQLTALTYRFLsVLLKDGGKVSGG---VQKVHSSLAvetvkYIEAHYAEKLS 190
Cdd:PRK13503 116 VNQSVLQQVRQLVAQMEqqEESNDLEAIASREILFMQLL-VLLRKSSLQENGensDARLNQLLA-----WLEDHFAEEVN 189

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488215644 191 VEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKK 261
Cdd:PRK13503 190 WEALADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRR 260
ftrA PRK09393
transcriptional activator FtrA; Provisional
 180-274 3.31e-09

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 56.90  E-value: 3.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 180 YIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMF 259
Cdd:PRK09393 226 WMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGSEESLRHHF 305

                         90
                 ....*....|....*
gi 488215644 260 KKSTGETATNYRKRM 274
Cdd:PRK09393 306 RRRAATSPAAYRKRF 320
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 126-273 5.34e-09

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 56.19  E-value: 5.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 126 IILECMKDTEET-LENELQLTALtyrflSVLLKDGGKVSGGVQKVHSSLAVETVKYIEAHY-AEKLSVEEIAQHLAVNRS 203
Cdd:PRK09685 155 LLQQSMNGPALSeTESEALLEAL-----IALLRPALHQRESVQPRRERQFQKVVALIDQSIqEEILRPEWIAGELGISVR 229

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488215644 204 HLSRVFKNHmGTSIKEYLIGVRINRGAFLLS--LTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKR 273
Cdd:PRK09685 230 SLYRLFAEQ-GLVVAQYIRNRRLDRCADDLRpaADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRK 300
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
180-272 1.48e-08

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 54.63  E-value: 1.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 180 YIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMF 259
Cdd:PRK15121  13 WLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQYRFDSQQTFTRAF 92

                         90
                 ....*....|...
gi 488215644 260 KKSTGETATNYRK 272
Cdd:PRK15121  93 KKQFAQTPALYRR 105
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
44-271 2.13e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 51.21  E-value: 2.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  44 LHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGE---DPWMYC---------WLS----FGGSAAEEIIRQSL 107
Cdd:PRK13502  41 LVMVWRGNGLHVLNERPYRITRGDLFYIRAEDKHSYTSVNDlvlQNIIYCperlklnvnWQAmipgFQGAQWHPHWRLGS 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 108 FREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSvllkDGGKVSGgvqkvHSSLAVETVKYIEAHYAE 187
Cdd:PRK13502 121 MGMNQARQVINQLEHESNGRDPLANEMAELLFGQLVMTLKRHRYAT----DDLPATS-----RETLLDKLITALANSLEC 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 188 KLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETA 267
Cdd:PRK13502 192 PFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTP 271


                 ....
gi 488215644 268 TNYR 271
Cdd:PRK13502 272 SQWR 275
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
169-271 3.12e-06

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 45.86  E-value: 3.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 169 VHSSLAvetvkYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVG 248
Cdd:PRK11511  11 IHSILD-----WIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYG 85

                         90       100
                 ....*....|....*....|...
gi 488215644 249 FNSLVVFSRMFKKSTGETATNYR 271
Cdd:PRK11511  86 FESQQTLTRTFKNYFDVPPHKYR 108
PRK10296 PRK10296
DNA-binding transcriptional regulator ChbR; Provisional
 202-278 2.16e-05

DNA-binding transcriptional regulator ChbR; Provisional


Pssm-ID: 182362 [Multi-domain]  Cd Length: 278  Bit Score: 45.13  E-value: 2.16e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488215644 202 RSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKNEN 278
Cdd:PRK10296 202 QEYLTRATRRYYGKTPMQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPGSYRKKLTEFN 278
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 142-277 2.98e-05

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 44.53  E-value: 2.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 142 LQLTALTYRFLSVLLKDGGKVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHmGTSIKEYL 221
Cdd:PRK09978 112 LRKRALIFALLSVFLEDEHFIPLLLNVLQPNMRTRVCTVINNNIAHEWTLARIASELLMSPSLLKKKLREE-ETSYSQLL 190

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 488215644 222 IGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKNE 277
Cdd:PRK09978 191 TECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTEYQERSAQG 246
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
44-271 4.59e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 44.32  E-value: 4.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644  44 LHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGE---DPWMYC---------WLS----FGGSAAEEiirqsl 107
Cdd:PRK13500  71 LVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDlvlQNIIYCperlklnldWQGaipgFSASAGQP------ 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 108 fredQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGGKVSGGVQKVHS-SLAVETVKYIEAHYA 186
Cdd:PRK13500 145 ----HWRLGSVGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSeTLLDKLITRLAASLK 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 187 EKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGET 266
Cdd:PRK13500 221 SPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMT 300


                 ....*
gi 488215644 267 ATNYR 271
Cdd:PRK13500 301 PSQWR 305
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 170-270 4.79e-04

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 41.20  E-value: 4.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 170 HSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHmGTSIKEYLIGVRINRGAFLLSLTDESVESIAYQVGF 249
Cdd:PRK15186 179 QNTLAENIYNIIISDISRKWALKDISDSLYMSCSTLKRKLKQE-NTSFSEVYLNARMNKATKLLRNSEYNITRVAYMCGY 257

                         90       100
                 ....*....|....*....|.
gi 488215644 250 NSLVVFSRMFKKSTGETATNY 270
Cdd:PRK15186 258 DSASYFTCVFKKHFKTTPSEF 278
cupin_YbfI-like_N cd07001
AraC/XylS family transcriptional regulators similar to Bacillus subtilis YbfI, N-terminal ...
 26-76 7.11e-04

AraC/XylS family transcriptional regulators similar to Bacillus subtilis YbfI, N-terminal cupin domain; This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators, including YbfI, an uncharacterized Bacillus subtilis. In Pseudomonas putida, this protein is thought to regulate the expression of phenylserine aldolase. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


Pssm-ID: 380405 [Multi-domain]  Cd Length: 76  Bit Score: 37.76  E-value: 7.11e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488215644  26 SKTMPFHSfgpaiRNDYILHVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDS 76
Cdd:cd07001   12 QKSFPNHF-----HDFYVIGFIESGQRTLFCEGKEYTVEPGDLLLINPRDV 57
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 171-272 1.59e-03

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 39.59  E-value: 1.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488215644 171 SSLAVETVKY-----IEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHmGTSIKEYLIGVRINRGAFLLSLTDESVESIAY 245
Cdd:PRK15185 200 LSSAQITLKErvyniISSSPSRQWKLTDVADHIFMSTSTLKRKLAEE-GTSFSDIYLSARMNQAAKLLRIGNHNVNAVAL 278

                         90       100
                 ....*....|....*....|....*..
gi 488215644 246 QVGFNSLVVFSRMFKKSTGETATNYRK 272
Cdd:PRK15185 279 KCGYDSTSYFIQCFKKYFKTTPSTFIK 305
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 236-272 3.38e-03

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 34.82  E-value: 3.38e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 488215644  236 TDESVESIAYQVGFNSLVvFSRMFKKSTGETATNYRK 272
Cdd:pfam00165   7 TNLTIADIADELGFSRSY-FSRLFKKYTGVTPSQYRH 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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