|
Name |
Accession |
Description |
Interval |
E-value |
| TyrS |
COG0162 |
Tyrosyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tyrosyl-tRNA ... |
8-396 |
0e+00 |
|
Tyrosyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tyrosyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439932 [Multi-domain] Cd Length: 409 Bit Score: 598.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 8 LEIIKRGADEVLIEEELIKKLQKhKPLIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTGKNA 87
Cdd:COG0162 5 LELIWRGLIEQITDEELREKLAG-GPLTIYLGFDPTAPSLHLGHLVPLMKLRRFQDLGHRPIALIGGFTGMIGDPSGKSE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 88 TRPPLTAEEVAANAETYTKQVFKILDKD--KTVIRRNGDWFNKMSASEMI-KLASKSTVARMLERDDFSKRYKGGQSISI 164
Cdd:COG0162 84 ERKLLTEEQVAENAETIKEQVFKFLDFDdnKAEIVNNSDWLGKLSFIDFLrDLGKHFTVNRMLERDDVKKRLESGQGISF 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 165 HEFLYPLVQGYDSVAM----NADIELGGTDQKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNYIGIEE- 239
Cdd:COG0162 164 TEFSYPLLQGYDFVELyrryGCDLQLGGSDQWGNILAGRELQRRYGGEPQFGLTMPLLTGADG-TKMGKSEGNAIWLDEe 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 240 --PANEIFGKIMSISDELMWRYYELLSFKSLENIAKLKQDVAAGANPRDIKIELAKELIERFHSKEDAESAHQDFIQRFQ 317
Cdd:COG0162 243 ktSPYEFYQKWMNISDADVWRYLKLFTFLPLEEIEELEAEVAEGPNPREAKKRLAEEITALVHGEEAAEAAEEAFEALFG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 318 KNQIPDDINVVELN---QELPIANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKIIFAKGTNN-----VFQVGKRK 389
Cdd:COG0162 323 KGELPDDLPEVELSaaeGGIPLVDLLVEAGLAASKSEARRLIKQGGVSVNGEKVTDPDAVLTAGDLLhggylVLRVGKKK 402
|
....*..
gi 489116355 390 FAKIIIK 396
Cdd:COG0162 403 FALVKLK 409
|
|
| PRK13354 |
PRK13354 |
tyrosyl-tRNA synthetase; Provisional |
1-396 |
3.35e-159 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 237360 [Multi-domain] Cd Length: 410 Bit Score: 453.97 E-value: 3.35e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 1 MSSIKETLEIikRGA-DEVLIEEELIKKLQKHKPLIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQI 79
Cdd:PRK13354 2 KMNILEQLKW--RGAiNQETDEEKLRKSLKEGKPLTLYLGFDPTAPSLHIGHLVPLMKLKRFQDAGHRPVILIGGFTGKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 80 GDPTGKNATRPPLTAEEVAANAETYTKQVFKILDKDKTVIRRNGDWFNKMSASEMI-KLASKSTVARMLERDDFSKRYKG 158
Cdd:PRK13354 80 GDPSGKSKERKLLTDEQVQHNAKTYTEQIFKLFDFEKTEIVNNSDWLSKLNLIDFLrDYGKHFTVNRMLERDDVKSRLER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 159 GQSISIHEFLYPLVQGYDSVAMN----ADIELGGTDQKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNY 234
Cdd:PRK13354 160 EQGISFTEFFYPLLQAYDFVHLNrkedVDLQIGGTDQWGNILMGRDLQRKLEGEEQFGLTMPLLEGADG-TKMGKSAGGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 235 IGIEE---PANEIFGKIMSISDELMWRYYELLSFKSLENIAKLKQDVAAGANPRDIKIELAKELIERFHSKEDAESAHQD 311
Cdd:PRK13354 239 IWLDPektSPYEFYQFWMNIDDRDVVKYLKLFTDLSPDEIDELEAQLETEPNPRDAKKVLAEEITKFVHGEEAAEEAEKI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 312 FIQRFQKNQIPD-DINVVELNQE-LPIANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSD--AKIIFAK---GTNNVFQ 384
Cdd:PRK13354 319 FKALFSGDVKPLkDIPTFEVSAEtKNLVDLLVDLGLEPSKREARRLIQNGAIKINGEKVTDvdAIINPEDafdGKFVILR 398
|
410
....*....|..
gi 489116355 385 VGKRKFAKIIIK 396
Cdd:PRK13354 399 RGKKKFFLVKLK 410
|
|
| tyrS |
TIGR00234 |
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ... |
8-381 |
2.29e-130 |
|
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272976 [Multi-domain] Cd Length: 378 Bit Score: 379.43 E-value: 2.29e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 8 LEIIKRGADEVL--IEEELIKKLQKhkPLIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTGK 85
Cdd:TIGR00234 6 LLLTKRGLEVQTpeEEKDLLKLLER--PLKLYLGFDPTAPSLHLGHLVPLLKLRDFQQAGHEVIVLLGDFTALIGDPTGK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 86 NATRPPLTAEEVAANAETYTKQVFKILDKDKTVIRRNGDWFNKMSASEMIKLASKS-TVARMLERDDFSKRYKGGqsISI 164
Cdd:TIGR00234 84 SEVRKILTREEVQENAENIKKQIARFLDFEKAKFVYNSEWLLKLNYTDFIRLLGKIfTVNRMLRRDAFSSRFEEN--ISL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 165 HEFLYPLVQGYDSVAMNADIELGGTDQKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNYIGIEEPANEI 244
Cdd:TIGR00234 162 HEFIYPLLQAYDFVYLNVDLQLGGSDQWFNIRKGRDLARENLPSLQFGLTVPLLTPADG-EKMGKSLGGAVSLDEGKYDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 245 FGKIMSISDELMWRYYELLSFKSLENIAKLKQDvaAGANPRDIKIELAKELIERFHSKEDAESAHQDFIQRFQKNQIPDD 324
Cdd:TIGR00234 241 YQKVINTPDELVKKYLKLFTFLGLEEIEQLVEL--KGPNPREVKENLALEITKYVHGPEAALAAEEISEAIFSGGLNPDE 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 325 INVVELNQ---ELPIANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKIIFAKGTNN 381
Cdd:TIGR00234 319 VPIFRPEKfggPITLADLLVLSGLFPSKSEARRDIKNGGVYINGEKVEDLEPIRKELENN 378
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
34-298 |
1.14e-103 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 307.23 E-value: 1.14e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 34 LIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTGKNATRPPLTAEEVAANAETYTKQVFKILD 113
Cdd:cd00805 1 LKVYIGFDPTAPSLHLGHLVPLMKLRDFQQAGHEVIVLIGDATAMIGDPSGKSEERKLLDLELIRENAKYYKKQLKAILD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 114 ---KDKTVIRRNGDWFNKMSASEMIKLASKSTVARMLERDDFSKRYKGGQSISIHEFLYPLVQGYDSVAMNADIELGGTD 190
Cdd:cd00805 81 fipPEKAKFVNNSDWLLSLYTLDFLRLGKHFTVNRMLRRDAVKVRLEEEEGISFSEFIYPLLQAYDFVYLDVDLQLGGSD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 191 QKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNYI--GIEEPANEIFGKIMSISDELMWRYYELLSFKSL 268
Cdd:cd00805 161 QRGNITLGRDLIRKLGYKKVVGLTTPLLTGLDG-GKMSKSEGNAIwdPVLDSPYDVYQKIRNAFDPDVLEFLKLFTFLDY 239
|
250 260 270
....*....|....*....|....*....|
gi 489116355 269 ENIAKLKQDVAAGANPRDIKIELAKELIER 298
Cdd:cd00805 240 EEIEELEEEHAEGPLPRDAKKALAEELTKL 269
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
29-317 |
1.30e-89 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 272.23 E-value: 1.30e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 29 QKHKPLIIKFGCDPTAPdIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTgKNATRPPLTAEEVAANAetYTKQV 108
Cdd:pfam00579 1 KKNRPLRVYSGIDPTGP-LHLGYLVPLMKLRQFQQAGHEVFFLIGDLHAIIGDPS-KSPERKLLSRETVLENA--IKAQL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 109 FKILDKDKTVIRRNGDWFNKMSASEMI-KLASKSTVARMLERDDFSKRYKGGQSISIHEFLYPLVQGYDSVAMNADIELG 187
Cdd:pfam00579 77 ACGLDPEKAEIVNNSDWLEHLELAWLLrDLGKHFSLNRMLQFKDVKKRLEQGPGISLGEFTYPLLQAYDILLLKADLQPG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 188 GTDQKFNLLMGRELQKQQGQE---PQVIITMPLLEGLDGVKKMSKSSQN----YIGIEEPANEIFGKIMSISDELMWRYY 260
Cdd:pfam00579 157 GSDQWGNIELGRDLARRFNKKifkKPVGLTNPLLTGLDGGKKMSKSAGNsaifLDDDPESVYKKIQKAYTDPDREVRKDL 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 489116355 261 ELLSFKSLENIAKLKQdVAAGANPRDIKIELAKELIERFHSKEDAESAHQDFIQRFQ 317
Cdd:pfam00579 237 KLFTFLSNEEIEILEA-ELGKSPYREAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
|
|
| S4 |
smart00363 |
S4 RNA-binding domain; |
338-392 |
2.67e-06 |
|
S4 RNA-binding domain;
Pssm-ID: 214638 [Multi-domain] Cd Length: 60 Bit Score: 44.51 E-value: 2.67e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 489116355 338 NLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKIIFAKGTNNVFQVGKRKFAK 392
Cdd:smart00363 5 KFLARLGLAPSRSQARRLIEQGRVKVNGKKVTKPSYIVKPGDVISVRGKELKRLK 59
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TyrS |
COG0162 |
Tyrosyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tyrosyl-tRNA ... |
8-396 |
0e+00 |
|
Tyrosyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tyrosyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439932 [Multi-domain] Cd Length: 409 Bit Score: 598.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 8 LEIIKRGADEVLIEEELIKKLQKhKPLIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTGKNA 87
Cdd:COG0162 5 LELIWRGLIEQITDEELREKLAG-GPLTIYLGFDPTAPSLHLGHLVPLMKLRRFQDLGHRPIALIGGFTGMIGDPSGKSE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 88 TRPPLTAEEVAANAETYTKQVFKILDKD--KTVIRRNGDWFNKMSASEMI-KLASKSTVARMLERDDFSKRYKGGQSISI 164
Cdd:COG0162 84 ERKLLTEEQVAENAETIKEQVFKFLDFDdnKAEIVNNSDWLGKLSFIDFLrDLGKHFTVNRMLERDDVKKRLESGQGISF 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 165 HEFLYPLVQGYDSVAM----NADIELGGTDQKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNYIGIEE- 239
Cdd:COG0162 164 TEFSYPLLQGYDFVELyrryGCDLQLGGSDQWGNILAGRELQRRYGGEPQFGLTMPLLTGADG-TKMGKSEGNAIWLDEe 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 240 --PANEIFGKIMSISDELMWRYYELLSFKSLENIAKLKQDVAAGANPRDIKIELAKELIERFHSKEDAESAHQDFIQRFQ 317
Cdd:COG0162 243 ktSPYEFYQKWMNISDADVWRYLKLFTFLPLEEIEELEAEVAEGPNPREAKKRLAEEITALVHGEEAAEAAEEAFEALFG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 318 KNQIPDDINVVELN---QELPIANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKIIFAKGTNN-----VFQVGKRK 389
Cdd:COG0162 323 KGELPDDLPEVELSaaeGGIPLVDLLVEAGLAASKSEARRLIKQGGVSVNGEKVTDPDAVLTAGDLLhggylVLRVGKKK 402
|
....*..
gi 489116355 390 FAKIIIK 396
Cdd:COG0162 403 FALVKLK 409
|
|
| PRK13354 |
PRK13354 |
tyrosyl-tRNA synthetase; Provisional |
1-396 |
3.35e-159 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 237360 [Multi-domain] Cd Length: 410 Bit Score: 453.97 E-value: 3.35e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 1 MSSIKETLEIikRGA-DEVLIEEELIKKLQKHKPLIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQI 79
Cdd:PRK13354 2 KMNILEQLKW--RGAiNQETDEEKLRKSLKEGKPLTLYLGFDPTAPSLHIGHLVPLMKLKRFQDAGHRPVILIGGFTGKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 80 GDPTGKNATRPPLTAEEVAANAETYTKQVFKILDKDKTVIRRNGDWFNKMSASEMI-KLASKSTVARMLERDDFSKRYKG 158
Cdd:PRK13354 80 GDPSGKSKERKLLTDEQVQHNAKTYTEQIFKLFDFEKTEIVNNSDWLSKLNLIDFLrDYGKHFTVNRMLERDDVKSRLER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 159 GQSISIHEFLYPLVQGYDSVAMN----ADIELGGTDQKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNY 234
Cdd:PRK13354 160 EQGISFTEFFYPLLQAYDFVHLNrkedVDLQIGGTDQWGNILMGRDLQRKLEGEEQFGLTMPLLEGADG-TKMGKSAGGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 235 IGIEE---PANEIFGKIMSISDELMWRYYELLSFKSLENIAKLKQDVAAGANPRDIKIELAKELIERFHSKEDAESAHQD 311
Cdd:PRK13354 239 IWLDPektSPYEFYQFWMNIDDRDVVKYLKLFTDLSPDEIDELEAQLETEPNPRDAKKVLAEEITKFVHGEEAAEEAEKI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 312 FIQRFQKNQIPD-DINVVELNQE-LPIANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSD--AKIIFAK---GTNNVFQ 384
Cdd:PRK13354 319 FKALFSGDVKPLkDIPTFEVSAEtKNLVDLLVDLGLEPSKREARRLIQNGAIKINGEKVTDvdAIINPEDafdGKFVILR 398
|
410
....*....|..
gi 489116355 385 VGKRKFAKIIIK 396
Cdd:PRK13354 399 RGKKKFFLVKLK 410
|
|
| tyrS |
TIGR00234 |
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ... |
8-381 |
2.29e-130 |
|
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272976 [Multi-domain] Cd Length: 378 Bit Score: 379.43 E-value: 2.29e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 8 LEIIKRGADEVL--IEEELIKKLQKhkPLIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTGK 85
Cdd:TIGR00234 6 LLLTKRGLEVQTpeEEKDLLKLLER--PLKLYLGFDPTAPSLHLGHLVPLLKLRDFQQAGHEVIVLLGDFTALIGDPTGK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 86 NATRPPLTAEEVAANAETYTKQVFKILDKDKTVIRRNGDWFNKMSASEMIKLASKS-TVARMLERDDFSKRYKGGqsISI 164
Cdd:TIGR00234 84 SEVRKILTREEVQENAENIKKQIARFLDFEKAKFVYNSEWLLKLNYTDFIRLLGKIfTVNRMLRRDAFSSRFEEN--ISL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 165 HEFLYPLVQGYDSVAMNADIELGGTDQKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNYIGIEEPANEI 244
Cdd:TIGR00234 162 HEFIYPLLQAYDFVYLNVDLQLGGSDQWFNIRKGRDLARENLPSLQFGLTVPLLTPADG-EKMGKSLGGAVSLDEGKYDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 245 FGKIMSISDELMWRYYELLSFKSLENIAKLKQDvaAGANPRDIKIELAKELIERFHSKEDAESAHQDFIQRFQKNQIPDD 324
Cdd:TIGR00234 241 YQKVINTPDELVKKYLKLFTFLGLEEIEQLVEL--KGPNPREVKENLALEITKYVHGPEAALAAEEISEAIFSGGLNPDE 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 325 INVVELNQ---ELPIANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKIIFAKGTNN 381
Cdd:TIGR00234 319 VPIFRPEKfggPITLADLLVLSGLFPSKSEARRDIKNGGVYINGEKVEDLEPIRKELENN 378
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
34-298 |
1.14e-103 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 307.23 E-value: 1.14e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 34 LIIKFGCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTGKNATRPPLTAEEVAANAETYTKQVFKILD 113
Cdd:cd00805 1 LKVYIGFDPTAPSLHLGHLVPLMKLRDFQQAGHEVIVLIGDATAMIGDPSGKSEERKLLDLELIRENAKYYKKQLKAILD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 114 ---KDKTVIRRNGDWFNKMSASEMIKLASKSTVARMLERDDFSKRYKGGQSISIHEFLYPLVQGYDSVAMNADIELGGTD 190
Cdd:cd00805 81 fipPEKAKFVNNSDWLLSLYTLDFLRLGKHFTVNRMLRRDAVKVRLEEEEGISFSEFIYPLLQAYDFVYLDVDLQLGGSD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 191 QKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGvKKMSKSSQNYI--GIEEPANEIFGKIMSISDELMWRYYELLSFKSL 268
Cdd:cd00805 161 QRGNITLGRDLIRKLGYKKVVGLTTPLLTGLDG-GKMSKSEGNAIwdPVLDSPYDVYQKIRNAFDPDVLEFLKLFTFLDY 239
|
250 260 270
....*....|....*....|....*....|
gi 489116355 269 ENIAKLKQDVAAGANPRDIKIELAKELIER 298
Cdd:cd00805 240 EEIEELEEEHAEGPLPRDAKKALAEELTKL 269
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
29-317 |
1.30e-89 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 272.23 E-value: 1.30e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 29 QKHKPLIIKFGCDPTAPdIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTgKNATRPPLTAEEVAANAetYTKQV 108
Cdd:pfam00579 1 KKNRPLRVYSGIDPTGP-LHLGYLVPLMKLRQFQQAGHEVFFLIGDLHAIIGDPS-KSPERKLLSRETVLENA--IKAQL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 109 FKILDKDKTVIRRNGDWFNKMSASEMI-KLASKSTVARMLERDDFSKRYKGGQSISIHEFLYPLVQGYDSVAMNADIELG 187
Cdd:pfam00579 77 ACGLDPEKAEIVNNSDWLEHLELAWLLrDLGKHFSLNRMLQFKDVKKRLEQGPGISLGEFTYPLLQAYDILLLKADLQPG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 188 GTDQKFNLLMGRELQKQQGQE---PQVIITMPLLEGLDGVKKMSKSSQN----YIGIEEPANEIFGKIMSISDELMWRYY 260
Cdd:pfam00579 157 GSDQWGNIELGRDLARRFNKKifkKPVGLTNPLLTGLDGGKKMSKSAGNsaifLDDDPESVYKKIQKAYTDPDREVRKDL 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 489116355 261 ELLSFKSLENIAKLKQdVAAGANPRDIKIELAKELIERFHSKEDAESAHQDFIQRFQ 317
Cdd:pfam00579 237 KLFTFLSNEEIEILEA-ELGKSPYREAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
|
|
| Tyr_Trp_RS_core |
cd00395 |
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA ... |
39-297 |
9.26e-38 |
|
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS)/Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. These enzymes attach Tyr or Trp, respectively, to the appropriate tRNA. These class I enzymes are homodimers, which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173893 [Multi-domain] Cd Length: 273 Bit Score: 137.43 E-value: 9.26e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 39 GCDPTAPDIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDPTGKNATRPPLTAEEVAANAETYTKQVFKIL---DKD 115
Cdd:cd00395 5 GIDPTADSLHIGHLIGLLTFRRFQHAGHRPIFLIGGQTGIIGDPSGKKSERTLNDPEEVRQNIRRIAAQYLAVGifeDPT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 116 KTVIRRNGDWFNKMSASEMIKLASKS-TVARMLERDDFSKRYKGGqsISIHEFLYPLVQGYD----SVAMNADIELGGTD 190
Cdd:cd00395 85 QATLFNNSDWPGPLAHIQFLRDLGKHvYVNYMERKTSFQSRSEEG--ISATEFTYPPLQAADflllNTTEGCDIQPGGSD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 191 QKFNLLMGREL-QKQQGQEPQVIITMPLLEGLDGvKKMSKSSQN---YIGIEEPANEIFGKIMSISDELMWRYYELLSFK 266
Cdd:cd00395 163 QWGNITLGRELaRRFNGFTIAEGLTIPLVTKLDG-PKFGKSESGpkwLDTEKTSPYEFYQFWINAVDSDVINILKYFTFL 241
|
250 260 270
....*....|....*....|....*....|.
gi 489116355 267 SLENIAKLKQDVAAGANPRDIKIELAKELIE 297
Cdd:cd00395 242 SKEEIERLEQEQYEAPGYRVAQKTLAEEVTK 272
|
|
| PRK08560 |
PRK08560 |
tyrosyl-tRNA synthetase; Validated |
4-297 |
6.03e-29 |
|
tyrosyl-tRNA synthetase; Validated
Pssm-ID: 236286 [Multi-domain] Cd Length: 329 Bit Score: 114.96 E-value: 6.03e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 4 IKETLEIIKRGADEVLIEEELIKKLQKHKPLIIKFGCDPTAPdIHLGHTVVINKLKQLQDLGHEIHFLIGDFTAQIGDpt 83
Cdd:PRK08560 1 IEERLELITRNTEEVVTEEELRELLESKEEPKAYIGFEPSGK-IHLGHLLTMNKLADLQKAGFKVTVLLADWHAYLND-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 84 gKNatrpplTAEEVAANAEtYTKQVFKI--LDKDKTVIRRNGDW-FNKMSASEMIKLASKSTVARM----------LERD 150
Cdd:PRK08560 78 -KG------DLEEIRKVAE-YNKKVFEAlgLDPDKTEFVLGSEFqLDKEYWLLVLKLAKNTTLARArrsmtimgrrMEEP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 151 DFSKrykggqsisiheFLYPLVQGYDSVAMNADIELGGTDQKFNLLMGRELQKQQGQEPQVIITMPLLEGLDGV-KKMSK 229
Cdd:PRK08560 150 DVSK------------LVYPLMQVADIFYLDVDIAVGGMDQRKIHMLAREVLPKLGYKKPVCIHTPLLTGLDGGgIKMSK 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 230 S-SQNYIGIEEPANEIFGKIMS---------------ISDELMWRYYELLSFK---------SLENIAKLKQDVAAGA-N 283
Cdd:PRK08560 218 SkPGSAIFVHDSPEEIRRKIKKaycppgevegnpvleIAKYHIFPRYDPFVIErpekyggdlEYESYEELERDYAEGKlH 297
|
330
....*....|....
gi 489116355 284 PRDIKIELAKELIE 297
Cdd:PRK08560 298 PMDLKNAVAEYLIE 311
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
46-297 |
2.31e-15 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 75.70 E-value: 2.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 46 DIHLGHTV-VINKLKQLQDLGHEIHFLIGDFTAqigdptgknATRPPLTAEEVAANAETYTKQVFKI-LDKDKTVIRRNG 123
Cdd:cd00806 11 SLHLGHYLgAFRFWVWLQEAGYELFFFIADLHA---------LTVKQLDPEELRQNTRENAKDYLACgLDPEKSTIFFQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 124 DwfnKMSASEMI-KLASKSTVARmLER-DDFSKRYKGGQSISIHEFLYPLVQGYDSVAMNADIELGGTDQKFNLLMGREL 201
Cdd:cd00806 82 D---VPEHYELAwLLSCVVTFGE-LERmTGFKDKSAQGESVNIGLLTYPVLQAADILLYKACLVPVGIDQDPHLELTRDI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 202 ----QKQQGQ---EPQVIIT-----MPLLeglDGVKKMSKSSQ-NYIGIEEPANEIFGKIM-----SISDEL-------- 255
Cdd:cd00806 158 arrfNKLYGEifpKPAALLSkgaflPGLQ---GPSKKMSKSDPnNAIFLTDSPKEIKKKIMkaatdGGRTEHrrdgggpg 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 489116355 256 ---MWRYYELLSFKSLENIAKLKQDVAAGANPRDIKIELAKELIE 297
Cdd:cd00806 235 vsnLVEIYSAFFNDDDEELEEIDEYRSGGLGYGECKKLLAEAIQE 279
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
191-299 |
2.12e-10 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 61.60 E-value: 2.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 191 QKFNLLMGRELQkqqgqEPQVIIT--MPLLEGLDGVKKMSKSSQNYIGIEEPANEIFGKIMSI---SDEL---------- 255
Cdd:COG0180 163 RRFNHRYGEVFP-----EPEALIPeeGARIPGLDGRKKMSKSYGNTINLLDDPKEIRKKIKSAvtdSERLryddpgkpev 237
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 489116355 256 --MWRYYELLSfkSLENIAKLKQD-VAAGANPRDIKIELAKELIERF 299
Cdd:COG0180 238 cnLFTIYSAFS--GKEEVEELEAEyRAGGIGYGDLKKALAEAVVEFL 282
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
42-306 |
4.40e-09 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 57.34 E-value: 4.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 42 PTAPdIHLGHTVVINKLKQLQDLGHEIHFLIGD---FTAQIGDPTGKNATRppltaEEVAANaetytkqvfkIL----DK 114
Cdd:TIGR00233 11 PSGK-MHLGHYLGAIQTKWLQQFGVELFICIADlhaITVKQTDPDALRKAR-----EELAAD----------YLavglDP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 115 DKTVIRRNGDWfnkMSASEMIKLASKSTVARMLERDDFSKRYKGGQSISIHEFLYPLVQGYDSVAMNADIELGGTDQKFN 194
Cdd:TIGR00233 75 EKTFIFLQSDY---PEHYELAWLLSCQVTFGELKRMTQFKDKSQAENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQH 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 195 LLMGREL----QKQQGQE---PQVIIT--MPLLEGLDGvKKMSKSSQN-YIGIEEPANEIFGKIMS-------------- 250
Cdd:TIGR00233 152 LELTRDLaerfNKKFKNFfpkPESLISkfFPRLMGLSG-KKMSKSDPNsAIFLTDTPKQIKKKIRKaatdggrvtlfehr 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489116355 251 ----ISDELMwrYYELLSFKsLENIAKLKQDVAA----GANPRDIK-------IELAKELIERFHSKEDAE 306
Cdd:TIGR00233 231 ekpgVPNLLV--IYQYLSFF-LIDDDKLKEIYEAyksgKLGYGECKkalievlQEFLKEIQERRAEIAEEI 298
|
|
| PRK12282 |
PRK12282 |
tryptophanyl-tRNA synthetase II; Reviewed |
35-250 |
2.65e-08 |
|
tryptophanyl-tRNA synthetase II; Reviewed
Pssm-ID: 183400 [Multi-domain] Cd Length: 333 Bit Score: 54.86 E-value: 2.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 35 IIKFGCDPTAPdIHLGHTVviNKLKQ---LQDlGHEIHFLIGDFTAqigdptgknatrppLTaeEVAANAETYTKQVFKI 111
Cdd:PRK12282 4 IILTGDRPTGK-LHLGHYV--GSLKNrvaLQN-EHEQFVLIADQQA--------------LT--DNAKNPEKIRRNILEV 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 112 --------LDKDKTVIrrngdwfnkMSASEMIKLASKS-------TVARmLERDDFSK---RYKG-GQSISIHEFLYPLV 172
Cdd:PRK12282 64 aldylavgIDPAKSTI---------FIQSQIPELAELTmyymnlvTVAR-LERNPTVKteiAQKGfGRSIPAGFLTYPVS 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 173 QGYDSVAMNADIELGGTDQ------------KFNLLMGRELQKqqgqEPQVIIT-MPLLEGLDGVKKMSKSSQNYIGIEE 239
Cdd:PRK12282 134 QAADITAFKATLVPVGDDQlpmieqtreivrRFNSLYGTDVLV----EPEALLPeAGRLPGLDGKAKMSKSLGNAIYLSD 209
|
250
....*....|.
gi 489116355 240 PANEIFGKIMS 250
Cdd:PRK12282 210 DADTIKKKVMS 220
|
|
| PTZ00126 |
PTZ00126 |
tyrosyl-tRNA synthetase; Provisional |
3-306 |
1.74e-07 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 240282 [Multi-domain] Cd Length: 383 Bit Score: 52.77 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 3 SIKETLEIIKRGADEVLIEEELIKKLQKHKPLIIKFGCDPTApDIHLGHTV--VINkLKQLQDLGHEIHFLIGDFTAQIG 80
Cdd:PTZ00126 36 SLEERVKLCLSIGEECIQPEELRELLKLKERPICYDGFEPSG-RMHIAQGIlkAIN-VNKLTKAGCVFVFWVADWFALLN 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 81 DPTGKNATRPPLTAEevaanaetYTKQVFKILDKDKTVIR--RNGDWFNKMSA---SEMIKLASKSTVARM------LER 149
Cdd:PTZ00126 114 NKMGGDLEKIRKVGE--------YFIEVWKAAGMDMDNVRflWASEEINKNPNdywLRVMDIARSFNITRIkrcsqiMGR 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 150 DDfskrykgGQSISIHEFLYPLVQGYDSVAMNADIELGGTDQ-KFNLLmGREL--QKQQGQEPqVIITMPLLEGL-DGVK 225
Cdd:PTZ00126 186 SE-------GDEQPCAQILYPCMQCADIFYLKADICQLGMDQrKVNML-AREYcdKKKIKKKP-IILSHHMLPGLlEGQE 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 226 KMSKSSQNY-IGIEEPANEIFGKIMS-------ISDELMWRYYELLSFKSL-----------------ENIAKLKQDVAA 280
Cdd:PTZ00126 257 KMSKSDPNSaIFMEDSEEDVNRKIKKaycppgvIEGNPILAYFKSIVFPAFnsftvlrkeknggdvtyTTYEELEKDYLS 336
|
330 340 350
....*....|....*....|....*....|..
gi 489116355 281 GA-NPRDIKIELAK---ELIE--RFHSKEDAE 306
Cdd:PTZ00126 337 GAlHPGDLKPALAKylnLMLQpvRDHFQNNPE 368
|
|
| S4 |
smart00363 |
S4 RNA-binding domain; |
338-392 |
2.67e-06 |
|
S4 RNA-binding domain;
Pssm-ID: 214638 [Multi-domain] Cd Length: 60 Bit Score: 44.51 E-value: 2.67e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 489116355 338 NLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKIIFAKGTNNVFQVGKRKFAK 392
Cdd:smart00363 5 KFLARLGLAPSRSQARRLIEQGRVKVNGKKVTKPSYIVKPGDVISVRGKELKRLK 59
|
|
| S4 |
cd00165 |
S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, ... |
336-396 |
3.65e-06 |
|
S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized functional similarity between these three protein classes.
Pssm-ID: 238095 [Multi-domain] Cd Length: 70 Bit Score: 44.16 E-value: 3.65e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489116355 336 IANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKIIFAKGtnNVFQVGKRKFAKIIIK 396
Cdd:cd00165 3 LDKILARLGLAPSRSEARQLIKHGHVLVNGKVVTKPSYKVKPG--DVIEVDGKSIEEDIVY 61
|
|
| PTZ00348 |
PTZ00348 |
tyrosyl-tRNA synthetase; Provisional |
3-230 |
6.79e-06 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 173541 [Multi-domain] Cd Length: 682 Bit Score: 48.36 E-value: 6.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 3 SIKETLEIIKRGADEVLIEEELIKKLQKhKPLIIKF-GCDPTApDIHLGH----TVVINKLKQLqdlGHEIHFLIGDFTA 77
Cdd:PTZ00348 2 NTDERYKLLRSVGEECIQESELRNLIEK-KPLIRCYdGFEPSG-RMHIAQgifkAVNVNKCTQA---GCEFVFWVADWFA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 78 QIGDPTGKNATRPPLTAEevaanaetYTKQVFKI--LDKDKTV-------IRRNGDWFNKMsaseMIKLASKSTVARMLE 148
Cdd:PTZ00348 77 LMNDKVGGELEKIRIVGR--------YLIEVWKAagMDMDKVLflwsseeITNHANTYWRT----VLDIGRQNTIARIKK 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 149 RDDFSKRYKGgqSISIHEFLYPLVQGYDSVAMNADI-ELGGTDQKFNLL-------MGRELQKqqgqepqVIITMPLLEG 220
Cdd:PTZ00348 145 CCTIMGKTEG--TLTAAQVLYPLMQCADIFFLKADIcQLGLDQRKVNMLareycdlIGRKLKP-------VILSHHMLAG 215
|
250
....*....|.
gi 489116355 221 L-DGVKKMSKS 230
Cdd:PTZ00348 216 LkQGQAKMSKS 226
|
|
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
141-315 |
1.66e-05 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 46.24 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 141 STVARM--LER-----DdfsKRYKGGQSISIHEFLYPlvqgydsVAMNADIELGGTD-------------------QKFN 194
Cdd:PRK00927 94 NCITPLgeLERmtqfkD---KSAKQKENVSAGLFTYP-------VLMAADILLYKADlvpvgedqkqhleltrdiaRRFN 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 195 LLMGrELQKqqgqEPQVIIT--MPLLEGLDG-VKKMSKSS---QNYIGIEEPANEIFGKIMSI---SDEL---------- 255
Cdd:PRK00927 164 NLYG-EVFP----VPEPLIPkvGARVMGLDGpTKKMSKSDpndNNTINLLDDPKTIAKKIKKAvtdSERLreirydlpnk 238
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489116355 256 -----MWRYYELLSFKSLENIAK-----------LKQDVAaganprdikiELAKELIERFHSKEDAESAHQDFIQR 315
Cdd:PRK00927 239 pevsnLLTIYSALSGESIEELEAeyeaggkgygdFKKDLA----------EAVVEFLAPIRERYEELLADPAYLDE 304
|
|
| S4 |
pfam01479 |
S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was ... |
334-374 |
6.35e-05 |
|
S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA.
Pssm-ID: 396182 [Multi-domain] Cd Length: 48 Bit Score: 40.17 E-value: 6.35e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 489116355 334 LPIANLLKEAGLVASTSEANRMIQQGAVKIDGEKLSDAKII 374
Cdd:pfam01479 1 RRLDKVLARLGLASSRSQARQLIEHGRVLVNGKVVKDPSYR 41
|
|
| S4_2 |
pfam13275 |
S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was ... |
328-366 |
1.34e-03 |
|
S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4.
Pssm-ID: 433078 [Multi-domain] Cd Length: 65 Bit Score: 37.03 E-value: 1.34e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 489116355 328 VELNQE-LPIANLLKEAGLVASTSEANRMIQQGAVKIDGE 366
Cdd:pfam13275 1 IKIRGEyITLGQLLKLAGLVESGGEAKWFIAEGEVLVNGE 40
|
|
| PRK12284 |
PRK12284 |
tryptophanyl-tRNA synthetase; Reviewed |
167-251 |
1.98e-03 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237036 [Multi-domain] Cd Length: 431 Bit Score: 39.99 E-value: 1.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 167 FLYPLVQGYDSVAMNADIELGGTDQ------------KFNLLMGRELQKQqgqePQVII-----TMPlleGLDGvKKMSK 229
Cdd:PRK12284 134 FMYPVLMAADILMFNAHKVPVGRDQiqhiemardiaqRFNHLYGGEFFVL----PEAVIeesvaTLP---GLDG-RKMSK 205
|
90 100
....*....|....*....|..
gi 489116355 230 SSQNYIGIEEPANEIFGKIMSI 251
Cdd:PRK12284 206 SYDNTIPLFAPREELKKAIFSI 227
|
|
| PRK12556 |
PRK12556 |
tryptophanyl-tRNA synthetase; Provisional |
167-244 |
2.21e-03 |
|
tryptophanyl-tRNA synthetase; Provisional
Pssm-ID: 183592 [Multi-domain] Cd Length: 332 Bit Score: 39.71 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 167 FLYPLVQGYDSVAMNADIELGGTDQ------------KFNLLMGRELQKQQGQEPQVIITMPlleGLDGvKKMSKSSQNY 234
Cdd:PRK12556 135 YTYPILMAADILLFQATHVPVGKDQiqhieiardiatYFNHTFGDTFTLPEYVIQEEGAILP---GLDG-RKMSKSYGNV 210
|
90
....*....|
gi 489116355 235 IGIEEPANEI 244
Cdd:PRK12556 211 IPLFAEQEKL 220
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
191-342 |
4.02e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 39.65 E-value: 4.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 191 QKFNLLMGRELQKQQGQEPQVIITM-PLLEGLDGVKKMSKSSQNYIGIEEPANEIFgKIMSISDELMWRYYeLLSFKSLE 269
Cdd:TIGR01612 1221 KNLGKLFLEKIDEEKKKSEHMIKAMeAYIEDLDEIKEKSPEIENEMGIEMDIKAEM-ETFNISHDDDKDHH-IISKKHDE 1298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489116355 270 NIA-------KLKQDVAAGANPRDIKIELAKELIerfhskeDAESAHQDFIQRFqkNQIPDDINVVELNQELPIANLLKE 342
Cdd:TIGR01612 1299 NISdirekslKIIEDFSEESDINDIKKELQKNLL-------DAQKHNSDINLYL--NEIANIYNILKLNKIKKIIDEVKE 1369
|
|
| |
