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Conserved domains on  [gi|501756499|emb|CCG80552|]
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WD domain protein [Taphrina deformans PYCC 5710]

Protein Classification

Striatin and WD40 domain-containing protein( domain architecture ID 13744662)

Striatin and WD40 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Striatin pfam08232
Striatin family; Striatin is an intracellular protein which has a caveolin-binding motif, a ...
 17-153 1.07e-36

Striatin family; Striatin is an intracellular protein which has a caveolin-binding motif, a coiled-coil structure, a calmodulin-binding site, and a WD (pfam00400) repeat domain. It acts as a scaffold protein and is involved in signalling pathways.


:

Pssm-ID: 462401  Cd Length: 85  Bit Score: 131.86  E-value: 1.07e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499   17 LPNVIHFLQNESSRYERDRNFWELERAEMKARIAKLEGERKSNERMKDWYLRRLRMLEVALHEERLqsdpnakplpsvvd 96
Cdd:pfam08232   1 LPGVLHFLQTEWHRHERDRNAWEIERAEMKARIAKLEGERRGQENLKKDLKRRIKMLEYALKQESK-------------- 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 501756499   97 dehaekksrstrnsriehddayleliqssqaglraqagRNKSRAYLEKCLTEVTYLV 153
Cdd:pfam08232  67 --------------------------------------RKKSRQYLKKCLQEIGYLD 85
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 352-585 2.10e-19

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member cd00200:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 289  Bit Score: 88.93  E-value: 2.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 352 DEETDPVLK-LTGHEGSIddLLLDSSQSDNLmtLYSAGEDMVIRRWDLdltslnqysESTSPSVTFISHSRSINALAL-V 429
Cdd:cd00200   79 DLETGECVRtLTGHTSYV--SSVAFSPDGRI--LSSSSRDKTIKVWDV---------ETGKCLTTLRGHTDWVNSVAFsP 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 430 DGALI-SCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCNLSD-DRFAAGYSDGSVKIYSINNDKSTMSLfdgrlt 507
Cdd:cd00200  146 DGTFVaSSSQDGTIKLWDLRTG--KCVATLTGHTGEV--NSVAFSPDgEKLLSSSSDGTIKLWDLSTGKCLGTL------ 215

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501756499 508 TGRTTSVAdlaSVSFMNQTFLCVNLDDDG-LRFYNTRSGELVREIpiTEPGGSPRCLCAVPAESQFVTGFSDGRVRTYS 585
Cdd:cd00200  216 RGHENGVN---SVAFSPDGYLLASGSEDGtIRVWDLRTGECVQTL--SGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
 
Name Accession Description Interval E-value
Striatin pfam08232
Striatin family; Striatin is an intracellular protein which has a caveolin-binding motif, a ...
 17-153 1.07e-36

Striatin family; Striatin is an intracellular protein which has a caveolin-binding motif, a coiled-coil structure, a calmodulin-binding site, and a WD (pfam00400) repeat domain. It acts as a scaffold protein and is involved in signalling pathways.


Pssm-ID: 462401  Cd Length: 85  Bit Score: 131.86  E-value: 1.07e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499   17 LPNVIHFLQNESSRYERDRNFWELERAEMKARIAKLEGERKSNERMKDWYLRRLRMLEVALHEERLqsdpnakplpsvvd 96
Cdd:pfam08232   1 LPGVLHFLQTEWHRHERDRNAWEIERAEMKARIAKLEGERRGQENLKKDLKRRIKMLEYALKQESK-------------- 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 501756499   97 dehaekksrstrnsriehddayleliqssqaglraqagRNKSRAYLEKCLTEVTYLV 153
Cdd:pfam08232  67 --------------------------------------RKKSRQYLKKCLQEIGYLD 85
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 352-585 2.10e-19

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 88.93  E-value: 2.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 352 DEETDPVLK-LTGHEGSIddLLLDSSQSDNLmtLYSAGEDMVIRRWDLdltslnqysESTSPSVTFISHSRSINALAL-V 429
Cdd:cd00200   79 DLETGECVRtLTGHTSYV--SSVAFSPDGRI--LSSSSRDKTIKVWDV---------ETGKCLTTLRGHTDWVNSVAFsP 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 430 DGALI-SCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCNLSD-DRFAAGYSDGSVKIYSINNDKSTMSLfdgrlt 507
Cdd:cd00200  146 DGTFVaSSSQDGTIKLWDLRTG--KCVATLTGHTGEV--NSVAFSPDgEKLLSSSSDGTIKLWDLSTGKCLGTL------ 215

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501756499 508 TGRTTSVAdlaSVSFMNQTFLCVNLDDDG-LRFYNTRSGELVREIpiTEPGGSPRCLCAVPAESQFVTGFSDGRVRTYS 585
Cdd:cd00200  216 RGHENGVN---SVAFSPDGYLLASGSEDGtIRVWDLRTGECVQTL--SGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
341-582 1.28e-17

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 85.35  E-value: 1.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 341 VAVGS---VIHLYQDEETDPVLKLTGHEGSIDDLLL--DSSqsdnlmTLYSAGEDMVIRRWDLDltslnqyseSTSPSVT 415
Cdd:COG2319  135 LASGSadgTVRLWDLATGKLLRTLTGHSGAVTSVAFspDGK------LLASGSDDGTVRLWDLA---------TGKLLRT 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 416 FISHSRSINALAL-VDGALI-SCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCnLSDD--RFAAGYSDGSVKIYS 491
Cdd:COG2319  200 LTGHTGAVRSVAFsPDGKLLaSGSADGTVRLWDLATG--KLLRTLTGHSGSV--RSVA-FSPDgrLLASGSADGTVRLWD 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 492 INNDKSTmslfdgRLTTGRTTSVADLAsVSFMNQTFLCVNlDDDGLRFYNTRSGELVREipITEPGGSPRCLCAVPAESQ 571
Cdd:COG2319  275 LATGELL------RTLTGHSGGVNSVA-FSPDGKLLASGS-DDGTVRLWDLATGKLLRT--LTGHTGAVRSVAFSPDGKT 344

                        250
                 ....*....|.
gi 501756499 572 FVTGFSDGRVR 582
Cdd:COG2319  345 LASGSDDGTVR 355
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 454-496 1.26e-03

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 38.41  E-value: 1.26e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 501756499  454 RVWRISGPANEVFPTSLCNLSDDRF-AAGYSDGSVKIYSINNDK 496
Cdd:pfam12894  28 RVWTLSPDKEDLEVTSLAWRPDGKLlAVGYSDGTVRLLDAENGK 71
PTZ00420 PTZ00420
coronin; Provisional
 346-461 1.46e-03

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 41.47  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 346 VIHLYQDEETDPVLKLTGHEGSIDDLLLDSSQSDnlmTLYSAGEDMVIRRWDLDLTSLNqYSESTSPSVTFISHSRSINA 425
Cdd:PTZ00420  55 AIRLENQMRKPPVIKLKGHTSSILDLQFNPCFSE---ILASGSEDLTIRVWEIPHNDES-VKEIKDPQCILKGHKKKISI 130

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 501756499 426 LALVD-GALISCSA--DASIRRWDTRsgDSRRVWRISGP 461
Cdd:PTZ00420 131 IDWNPmNYYIMCSSgfDSFVNIWDIE--NEKRAFQINMP 167
 
Name Accession Description Interval E-value
Striatin pfam08232
Striatin family; Striatin is an intracellular protein which has a caveolin-binding motif, a ...
 17-153 1.07e-36

Striatin family; Striatin is an intracellular protein which has a caveolin-binding motif, a coiled-coil structure, a calmodulin-binding site, and a WD (pfam00400) repeat domain. It acts as a scaffold protein and is involved in signalling pathways.


Pssm-ID: 462401  Cd Length: 85  Bit Score: 131.86  E-value: 1.07e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499   17 LPNVIHFLQNESSRYERDRNFWELERAEMKARIAKLEGERKSNERMKDWYLRRLRMLEVALHEERLqsdpnakplpsvvd 96
Cdd:pfam08232   1 LPGVLHFLQTEWHRHERDRNAWEIERAEMKARIAKLEGERRGQENLKKDLKRRIKMLEYALKQESK-------------- 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 501756499   97 dehaekksrstrnsriehddayleliqssqaglraqagRNKSRAYLEKCLTEVTYLV 153
Cdd:pfam08232  67 --------------------------------------RKKSRQYLKKCLQEIGYLD 85
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 352-585 2.10e-19

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 88.93  E-value: 2.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 352 DEETDPVLK-LTGHEGSIddLLLDSSQSDNLmtLYSAGEDMVIRRWDLdltslnqysESTSPSVTFISHSRSINALAL-V 429
Cdd:cd00200   79 DLETGECVRtLTGHTSYV--SSVAFSPDGRI--LSSSSRDKTIKVWDV---------ETGKCLTTLRGHTDWVNSVAFsP 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 430 DGALI-SCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCNLSD-DRFAAGYSDGSVKIYSINNDKSTMSLfdgrlt 507
Cdd:cd00200  146 DGTFVaSSSQDGTIKLWDLRTG--KCVATLTGHTGEV--NSVAFSPDgEKLLSSSSDGTIKLWDLSTGKCLGTL------ 215

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501756499 508 TGRTTSVAdlaSVSFMNQTFLCVNLDDDG-LRFYNTRSGELVREIpiTEPGGSPRCLCAVPAESQFVTGFSDGRVRTYS 585
Cdd:cd00200  216 RGHENGVN---SVAFSPDGYLLASGSEDGtIRVWDLRTGECVQTL--SGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
341-582 1.28e-17

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 85.35  E-value: 1.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 341 VAVGS---VIHLYQDEETDPVLKLTGHEGSIDDLLL--DSSqsdnlmTLYSAGEDMVIRRWDLDltslnqyseSTSPSVT 415
Cdd:COG2319  135 LASGSadgTVRLWDLATGKLLRTLTGHSGAVTSVAFspDGK------LLASGSDDGTVRLWDLA---------TGKLLRT 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 416 FISHSRSINALAL-VDGALI-SCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCnLSDD--RFAAGYSDGSVKIYS 491
Cdd:COG2319  200 LTGHTGAVRSVAFsPDGKLLaSGSADGTVRLWDLATG--KLLRTLTGHSGSV--RSVA-FSPDgrLLASGSADGTVRLWD 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 492 INNDKSTmslfdgRLTTGRTTSVADLAsVSFMNQTFLCVNlDDDGLRFYNTRSGELVREipITEPGGSPRCLCAVPAESQ 571
Cdd:COG2319  275 LATGELL------RTLTGHSGGVNSVA-FSPDGKLLASGS-DDGTVRLWDLATGKLLRT--LTGHTGAVRSVAFSPDGKT 344

                        250
                 ....*....|.
gi 501756499 572 FVTGFSDGRVR 582
Cdd:COG2319  345 LASGSDDGTVR 355
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 361-601 6.60e-17

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 81.61  E-value: 6.60e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 361 LTGHEGSIDDLLLdssqSDNLMTLYSAGEDMVIRRWDLdltslnqysESTSPSVTFISHSRSINALALVDGA--LISCSA 438
Cdd:cd00200    5 LKGHTGGVTCVAF----SPDGKLLATGSGDGTIKVWDL---------ETGELLRTLKGHTGPVRDVAASADGtyLASGSS 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 439 DASIRRWDTRSGDSRRVWRisGPANEVFptSLCNLSDDRF-AAGYSDGSVKIYSINNDKSTMSLfdgrltTGRTTSVadl 517
Cdd:cd00200   72 DKTIRLWDLETGECVRTLT--GHTSYVS--SVAFSPDGRIlSSSSRDKTIKVWDVETGKCLTTL------RGHTDWV--- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 518 ASVSFM-NQTFLCVNLDDDGLRFYNTRSGELVREIPITEpgGSPRCLCAVPAESQFVTGFSDGRVRTYSYRGDRVQEVNV 596
Cdd:cd00200  139 NSVAFSpDGTFVASSSQDGTIKLWDLRTGKCVATLTGHT--GEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLR 216


                 ....*
gi 501756499 597 GEDGG 601
Cdd:cd00200  217 GHENG 221
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 341-491 5.72e-14

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 72.75  E-value: 5.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 341 VAVGSV---IHLYQDEETDPVLKLTGHEGSIddllLDSSQSDNLMTLYSAGEDMVIRRWDLDltslnqyseSTSPSVTFI 417
Cdd:cd00200  150 VASSSQdgtIKLWDLRTGKCVATLTGHTGEV----NSVAFSPDGEKLLSSSSDGTIKLWDLS---------TGKCLGTLR 216

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 501756499 418 SHSRSINALA-LVDGALI-SCSADASIRRWDTRSGDSRRVwrISGPANEVfpTSLCnLSDD--RFAAGYSDGSVKIYS 491
Cdd:cd00200  217 GHENGVNSVAfSPDGYLLaSGSEDGTIRVWDLRTGECVQT--LSGHTNSV--TSLA-WSPDgkRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
337-601 9.77e-14

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 73.41  E-value: 9.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 337 VWLAVAVGSVIHLYQDEETDPVLKLTGHEGSIDDLLLdssqSDNLMTLYSAGEDMVIRRWDLDltslnqyseSTSPSVTF 416
Cdd:COG2319   50 RLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAF----SPDGRLLASASADGTVRLWDLA---------TGLLLRTL 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 417 ISHSRSINALAL-VDGA-LISCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCnLSDD--RFAAGYSDGSVKIYSI 492
Cdd:COG2319  117 TGHTGAVRSVAFsPDGKtLASGSADGTVRLWDLATG--KLLRTLTGHSGAV--TSVA-FSPDgkLLASGSDDGTVRLWDL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 493 NNDKSTMSLfdgRLTTGRTTSVA---D---LASVSfmnqtflcvnlDDDGLRFYNTRSGELVReiPITEPGGSPRCLCAV 566
Cdd:COG2319  192 ATGKLLRTL---TGHTGAVRSVAfspDgklLASGS-----------ADGTVRLWDLATGKLLR--TLTGHSGSVRSVAFS 255

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 501756499 567 PAESQFVTGFSDGRVRTYSYRGDRVQEVNVGEDGG 601
Cdd:COG2319  256 PDGRLLASGSADGTVRLWDLATGELLRTLTGHSGG 290
WD40 COG2319
WD40 repeat [General function prediction only];
341-518 2.44e-11

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 66.09  E-value: 2.44e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 341 VAVGS---VIHLYQDEETDPVLKLTGHEGSIDDLLLdssqSDNLMTLYSAGEDMVIRRWDLDltslnqyseSTSPSVTFI 417
Cdd:COG2319  219 LASGSadgTVRLWDLATGKLLRTLTGHSGSVRSVAF----SPDGRLLASGSADGTVRLWDLA---------TGELLRTLT 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 418 SHSRSINALALV-DGA-LISCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCnLSDD--RFAAGYSDGSVKIYSIN 493
Cdd:COG2319  286 GHSGGVNSVAFSpDGKlLASGSDDGTVRLWDLATG--KLLRTLTGHTGAV--RSVA-FSPDgkTLASGSDDGTVRLWDLA 360

                        170       180
                 ....*....|....*....|....*
gi 501756499 494 NDKSTMSLfdgrltTGRTTSVADLA 518
Cdd:COG2319  361 TGELLRTL------TGHTGAVTSVA 379
WD40 COG2319
WD40 repeat [General function prediction only];
341-494 2.08e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 56.84  E-value: 2.08e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 341 VAVGS---VIHLYQDEETDPVLKLTGHEGSIDDLLLdssqSDNLMTLYSAGEDMVIRRWDLDltslnqyseSTSPSVTFI 417
Cdd:COG2319  261 LASGSadgTVRLWDLATGELLRTLTGHSGGVNSVAF----SPDGKLLASGSDDGTVRLWDLA---------TGKLLRTLT 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 418 SHSRSINALALV-DGA-LISCSADASIRRWDTRSGdsRRVWRISGPANEVfpTSLCnLSDD--RFAAGYSDGSVKIYSIN 493
Cdd:COG2319  328 GHTGAVRSVAFSpDGKtLASGSDDGTVRLWDLATG--ELLRTLTGHTGAV--TSVA-FSPDgrTLASGSADGTVRLWDLA 402


                 .
gi 501756499 494 N 494
Cdd:COG2319  403 T 403
WD40 COG2319
WD40 repeat [General function prediction only];
392-611 5.62e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 55.30  E-value: 5.62e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 392 VIRRWDLDLTSLNQYSESTSPSVTFISHSRSINALAL--VDGALISCSADASIRRWDTRSGdsRRVWRISGPANEVfpTS 469
Cdd:COG2319   50 RLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFspDGRLLASASADGTVRLWDLATG--LLLRTLTGHTGAV--RS 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 470 LCnLSDD--RFAAGYSDGSVKIYSINNDKSTMSLfdgRLTTGRTTSVA---D---LASVSfmnqtflcvnlDDDGLRFYN 541
Cdd:COG2319  126 VA-FSPDgkTLASGSADGTVRLWDLATGKLLRTL---TGHSGAVTSVAfspDgklLASGS-----------DDGTVRLWD 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 501756499 542 TRSGELVREipITEPGGSPRCLCAVPAESQFVTGFSDGRVRTYSYRGDRVQEVNVGEDGGDIAIV------HLASS 611
Cdd:COG2319  191 LATGKLLRT--LTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAfspdgrLLASG 264
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
385-601 2.96e-04

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 43.08  E-value: 2.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 385 YSAGEDMVIRRWDLDLTSLNQYSESTSPSVTFISHSRsinalalvDGAL-ISCSADASIRRWDTRSGDsrrVWRISGPAN 463
Cdd:COG4257   32 FTDQGGGRIGRLDPATGEFTEYPLGGGSGPHGIAVDP--------DGNLwFTDNGNNRIGRIDPKTGE---ITTFALPGG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 464 EVFPTSLCNLSDDR--FAAGYSDgsvKIYSINNDKSTMSLFDGRLTTGRTTSVAdlasvsfmnqtflcvnLDDDG----- 536
Cdd:COG4257  101 GSNPHGIAFDPDGNlwFTDQGGN---RIGRLDPATGEVTEFPLPTGGAGPYGIA----------------VDPDGnlwvt 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501756499 537 ------LRFYNTRSGElVREIPITEPGGSPRCLCAVPAESQFVTGFSDGRVRTYSYRGDRVQEVNVGEDGG 601
Cdd:COG4257  162 dfganaIGRIDPDTGT-LTEYALPTPGAGPRGLAVDPDGNLWVADTGSGRIGRFDPKTGTVTEYPLPGGGA 231
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 454-496 1.26e-03

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 38.41  E-value: 1.26e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 501756499  454 RVWRISGPANEVFPTSLCNLSDDRF-AAGYSDGSVKIYSINNDK 496
Cdd:pfam12894  28 RVWTLSPDKEDLEVTSLAWRPDGKLlAVGYSDGTVRLLDAENGK 71
PTZ00420 PTZ00420
coronin; Provisional
 346-461 1.46e-03

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 41.47  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 346 VIHLYQDEETDPVLKLTGHEGSIDDLLLDSSQSDnlmTLYSAGEDMVIRRWDLDLTSLNqYSESTSPSVTFISHSRSINA 425
Cdd:PTZ00420  55 AIRLENQMRKPPVIKLKGHTSSILDLQFNPCFSE---ILASGSEDLTIRVWEIPHNDES-VKEIKDPQCILKGHKKKISI 130

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 501756499 426 LALVD-GALISCSA--DASIRRWDTRsgDSRRVWRISGP 461
Cdd:PTZ00420 131 IDWNPmNYYIMCSSgfDSFVNIWDIE--NEKRAFQINMP 167
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 393-614 5.23e-03

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 39.10  E-value: 5.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 393 IRRWDLDLTSLNqysestspsvTFISHSRSINALALV-DGALISCSADASIRRWDTRSGDSRRVWRISGPanevfPTSLC 471
Cdd:COG3386   31 IHRYDPDGGAVE----------VFAEPSGRPNGLAFDpDGRLLVADHGRGLVRFDPADGEVTVLADEYGK-----PLNRP 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501756499 472 NlsDDRFAagySDGSvkIYSinndkSTMSLFD--GRL----TTGRTTSVADlaSVSFMNQtfLCvnLDDDGLRFY--NTR 543
Cdd:COG3386   96 N--DGVVD---PDGR--LYF-----TDMGEYLptGALyrvdPDGSLRVLAD--GLTFPNG--IA--FSPDGRTLYvaDTG 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 501756499 544 SGELVReIPITEPG--GSPRCLCAVPAESQFVTGF---SDGRVRTYSYRGDRVQEVNvgEDGGDIAIVHLASSQVT 614
Cdd:COG3386  158 AGRIYR-FDLDADGtlGNRRVFADLPDGPGGPDGLavdADGNLWVALWGGGGVVRFD--PDGELLGRIELPERRPT 230
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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