|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-431 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 865.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 1 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 81 KEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEK 160
Cdd:PRK01117 81 KEIDELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 161 LKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTS 240
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 241 SNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQ 320
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 321 LNSLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIK 400
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 5542174 401 RIEELTGVPIDIISTGPDRTETMILRDPFDA 431
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-426 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 808.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 3 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 83 MKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLK 162
Cdd:COG0104 81 IDGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 163 EVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 242
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 243 TTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLN 322
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 323 SLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRI 402
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 5542174 403 EELTGVPIDIISTGPDRTETMILR 426
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-423 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 756.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 85 ELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLKEV 164
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 165 MEYHNFQLVNYYKaEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 244
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 245 AGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSL 324
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 325 SGFCLTKLDVLDGLKEVKLCVAYRmPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEE 404
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYE-LDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 5542174 405 LTGVPIDIISTGPDRTETM 423
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-424 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 741.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 3 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 83 MKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARgakaIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLK 162
Cdd:smart00788 81 IEELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 163 EVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 242
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 243 TTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLN 322
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 323 SLSGFCLTKLDVLDGLKEVKLCVAYRmPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRI 402
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYK-LDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 5542174 403 EELTGVPIDIISTGPDRTETMI 424
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-430 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 729.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 85 ELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLKEV 164
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 165 MEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 244
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 245 AGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSL 324
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 325 SGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEE 404
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*.
gi 5542174 405 LTGVPIDIISTGPDRTETMILRDPFD 430
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKELL 425
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-424 |
2.61e-179 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 502.41 E-value: 2.61e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 2 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 82 EMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDlfdketfaekl 161
Cdd:cd03108 81 EIEELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 162 kevmeyhnfqlvnyykaeavdyqkvlddtmavadiltSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSS 241
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 242 NTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQL 321
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 322 NSLSGFCLTKLDVldglkevklcvayrmpdgrevtttplaaddwkgvepiyetmpgwsestfgvkdrsglpqAALNYIKR 401
Cdd:cd03108 273 NGLTELALTKLDV-----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 5542174 402 IEELTGVPIDIISTGPDRTETMI 424
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
8.96e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.17 E-value: 8.96e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQ-GGHNAGHTlVIN--GEKTVLHLIPSGILREN-VTSIIGNGVVLSPAALM 80
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 81 KEMKELEDRGIPVRERLLLSE-ACPLILDYHValdnaREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAE 159
Cdd:NF038379 82 EEIEELEDAGHDVGKRLLIHEqATVIELHKHV-----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 160 KLKEVMEYHnFQLVNYYKAeavdyqkvlddtmavadiltsmvvdvsdllDQARQRGDFVMFEGAQGTLLDIDHGTYPYVT 239
Cdd:NF038379 157 VRDQPWEIA-ERVVDNALY------------------------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 240 SSNTTAGGVATGSGLGPRYVDY--VLGILKAYSTRVGA-----GPFPTEL-FDETGeflckQGNEFGATTGRRRRTGWLD 311
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|.
gi 5542174 312 TVAVRRAVQLN 322
Cdd:NF038379 281 AEQVREAVQAN 291
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-431 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 865.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 1 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 81 KEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEK 160
Cdd:PRK01117 81 KEIDELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 161 LKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTS 240
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 241 SNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQ 320
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 321 LNSLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIK 400
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 5542174 401 RIEELTGVPIDIISTGPDRTETMILRDPFDA 431
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-426 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 808.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 3 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 83 MKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLK 162
Cdd:COG0104 81 IDGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 163 EVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 242
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 243 TTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLN 322
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 323 SLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRI 402
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 5542174 403 EELTGVPIDIISTGPDRTETMILR 426
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-423 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 756.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 85 ELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLKEV 164
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 165 MEYHNFQLVNYYKaEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 244
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 245 AGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSL 324
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 325 SGFCLTKLDVLDGLKEVKLCVAYRmPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEE 404
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYE-LDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 5542174 405 LTGVPIDIISTGPDRTETM 423
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-424 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 741.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 3 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 83 MKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARgakaIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLK 162
Cdd:smart00788 81 IEELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 163 EVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 242
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 243 TTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLN 322
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 323 SLSGFCLTKLDVLDGLKEVKLCVAYRmPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRI 402
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYK-LDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 5542174 403 EELTGVPIDIISTGPDRTETMI 424
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-430 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 729.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 85 ELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLKEV 164
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 165 MEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 244
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 245 AGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSL 324
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 325 SGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEE 404
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*.
gi 5542174 405 LTGVPIDIISTGPDRTETMILRDPFD 430
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKELL 425
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
1-426 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 549.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 1 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVIN-GEKTVLHLIPSGILRENVTSIIGNGVVLSPAAL 79
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNDeGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 80 MKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAE 159
Cdd:PLN02513 82 FEEIDGLESNGVSCEGRLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 160 KLKEVMEYHNFQLvNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVT 239
Cdd:PLN02513 162 KLRELLADAAARF-EGFEYDASMVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFVT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 240 SSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAV 319
Cdd:PLN02513 241 SSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYSC 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 320 QLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYI 399
Cdd:PLN02513 321 QINGFTSLNLTKLDVLSGLPEIKIGVAYKTPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAYV 400
|
410 420
....*....|....*....|....*..
gi 5542174 400 KRIEELTGVPIDIISTGPDRTETMILR 426
Cdd:PLN02513 401 ERIEELVGVPVHYIGVGPGRDALIVKP 427
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
1-427 |
1.18e-180 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 510.73 E-value: 1.18e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 1 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 80
Cdd:PTZ00350 12 SKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 81 KEMKELEDRGIPVRERLLLSEACPLILDYHVALDNARE--KARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFA 158
Cdd:PTZ00350 92 EEIEQLTKKGINLLGRLYISDRAHLVFDLHQAIDGIQEseKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 159 EKLKEVMEYHNFQlvnyYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYV 238
Cdd:PTZ00350 172 KKYRKLVEKLQEQ----YNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 239 TSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRA 318
Cdd:PTZ00350 248 TSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 319 VQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMP-DGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALN 397
Cdd:PTZ00350 328 QMINGFDSINLTKLDVLSGLKEIKICVNYKNKgTGLEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQK 407
|
410 420 430
....*....|....*....|....*....|
gi 5542174 398 YIKRIEELTGVPIDIISTGPDRtETMILRD 427
Cdd:PTZ00350 408 YVLFIEELLGVPIVWIGVGPNR-ENMIVKK 436
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-424 |
2.61e-179 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 502.41 E-value: 2.61e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 2 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 82 EMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDlfdketfaekl 161
Cdd:cd03108 81 EIEELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 162 kevmeyhnfqlvnyykaeavdyqkvlddtmavadiltSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSS 241
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 242 NTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQL 321
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 322 NSLSGFCLTKLDVldglkevklcvayrmpdgrevtttplaaddwkgvepiyetmpgwsestfgvkdrsglpqAALNYIKR 401
Cdd:cd03108 273 NGLTELALTKLDV-----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 5542174 402 IEELTGVPIDIISTGPDRTETMI 424
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
5-425 |
4.60e-142 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 412.42 E-value: 4.60e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 84
Cdd:PRK13787 5 LVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 85 ELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGA-KAIGTTGRGIGPAYEDKVALRGLRVGDLFDKeTFAEKLKE 163
Cdd:PRK13787 85 RLQKEGFPVKDKLLLSDACHLLFPYHSQIDSARETTSSQeHKIGTTKKGIGICYADKMMRTGLRVGDLLDK-SYKRRLKH 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 164 VMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNT 243
Cdd:PRK13787 164 LVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 244 TAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNS 323
Cdd:PRK13787 244 TTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSVRING 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 324 LSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPlaADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIE 403
Cdd:PRK13787 324 ITSIALTKIDILSDYDTIPVAVGYKL-NGKTLDCFP--SQGLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYISALE 400
|
410 420
....*....|....*....|..
gi 5542174 404 ELTGVPIDIISTGPDRTETMIL 425
Cdd:PRK13787 401 KWIGVKINLVSTGPDRKDTIIG 422
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
2-424 |
9.96e-135 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 392.93 E-value: 9.96e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 2 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 81
Cdd:PRK13783 1 MKRVIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 82 EMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGaKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKL 161
Cdd:PRK13783 81 ELEELKEKFPDYSGRIFISELAHVVLPVHKELDEIIESVRK-NAIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 162 KEVMEYHNfqlvNYYKAEaVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGdfVMFEGAQGTLLDIDHGTYPYVTSS 241
Cdd:PRK13783 160 EKILSLYK----KLYGIE-FDVEKMMEDLLTFYEKIKDLVVSPVEIKRILEEKS--VLFEGTQGVLLDLDVGTYPYVTSS 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 242 NTTAGGVATGSGLgPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQL 321
Cdd:PRK13783 233 NCSTTGVSAGMGF-PVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 322 NSLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVtTTPLAADDWKGVEPIYETMPGWsESTFGVKdrsglpqaALNYIKR 401
Cdd:PRK13783 312 SGVDSLVMTKADVLNGFEKIKVCVRYEI-GGKEV-RDPSSLRDLEKAEPVYEEFDGW-KSLEDKN--------FLKFVDF 380
|
410 420
....*....|....*....|...
gi 5542174 402 IEELTGVPIDIISTGPdRTETMI 424
Cdd:PRK13783 381 IERETGRKIAYISTGP-KIEEIV 402
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
5-422 |
3.24e-133 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 389.54 E-value: 3.24e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILReNVTSIIGNGVVLSPAALMKEMK 84
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLL-DARVLIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 85 ELEDRGIPVR-ERLLLSEACPLILDYHVALDNAREKARGAKaIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLKE 163
Cdd:PRK13786 83 MLEKHGVKVDaEKLGIDAKTSIIMPYHIELDGLRESARTEK-IGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 164 VMEyhnfQLVNYYKAEAVDYQKVLDDTM-----AVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYV 238
Cdd:PRK13786 162 LAP----QKEKEIKELGGDPSIVRDEALidkylELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 239 TSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRA 318
Cdd:PRK13786 238 TSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 319 VQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNY 398
Cdd:PRK13786 318 IYLNGYTEIALTKLDVLTGLDPIKICVGYEL-DGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNY 396
|
410 420
....*....|....*....|....
gi 5542174 399 IKRIEELTGVPIDIISTGPDRTET 422
Cdd:PRK13786 397 VERLEELMGVPIKYISVGPGREQT 420
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
4-422 |
1.09e-131 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 384.93 E-value: 1.09e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 4 VVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEM 83
Cdd:PRK13788 4 IAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFAEER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 84 KELEDRGIPvrERLLLSEACPLILDYHVALDNarekarGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKLKE 163
Cdd:PRK13788 84 ENLRAGGLN--PKLLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERVER 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 164 VMEyhnfQLVNYYKAEAVD-YQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 242
Cdd:PRK13788 156 LLE----AKPNSTREAGWDtVEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTSSH 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 243 TTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQG----NEFGATTGRRRRTGWLDTVAVRRA 318
Cdd:PRK13788 232 PTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLKYA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 319 VQLNSLSGFCLTKLDVLDGLKEVKLCVAYRmPDGRevtttplaaddwkgvePIYETMPGWSESTfGVKDRSGLPQAALNY 398
Cdd:PRK13788 312 CEVNGFDGLVLTKLDVLSGLEKVKVCVEYD-DDGQ----------------PVYKELPGWGDLD-GVKSREALPKEAQAY 373
|
410 420
....*....|....*....|....
gi 5542174 399 IKRIEELTGVPIDIISTGPDRTET 422
Cdd:PRK13788 374 LELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
2-429 |
1.32e-123 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 365.50 E-value: 1.32e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 2 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 81
Cdd:PRK13784 2 SNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 82 EMKELEDRGIPVR-ERLLLSEACPLILDYHVALDNAREKARGAKaIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEK 160
Cdd:PRK13784 82 EITRLQAKGIAISaENLFVSESCTIITSYHKLLDAVRESNTSEK-IGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRSR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 161 LKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTS 240
Cdd:PRK13784 161 LAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 241 SNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQ 320
Cdd:PRK13784 241 SNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 321 LNSLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKgVEPIYETMPGWSESTFGVKDrsGLPQAALNYIK 400
Cdd:PRK13784 321 CSNLTSIALTKVDVLSDMDTLKVCIGYKY-EGKEIYCAYPGIDLYK-VEPILVEMEPFSIDETVTKD--NMPAALKTYLK 396
|
410 420
....*....|....*....|....*....
gi 5542174 401 RIEELTGVPIDIISTGPDRTETMILRDPF 429
Cdd:PRK13784 397 TIENHVGIPISSLAYGPSREQILFFEDYF 425
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
4-429 |
1.63e-120 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 358.30 E-value: 1.63e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 4 VVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVtSIIGNGVVLSPAALMKEM 83
Cdd:PRK13785 3 VTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGKI-GVLGNGCVVNPETLFDEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 84 KELEDRGIPVRERLllSEACPLILDYHVALDNARE--KARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAEKL 161
Cdd:PRK13785 82 DALRERGLDPDVRV--AERAHVILPYHRVLDGIEEeaKSDSDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 162 KEVMEYHNFQLVNYY------KAEAVDYQKVLDDTMAVADILTS--MVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHG 233
Cdd:PRK13785 160 EYVVPQKRALAEDVYgldaseTPEAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 234 TYPYVTSSNTTAGGVATGSGLGPRYVDY--VLGILKAYSTRVGAGPFPTEL---------------FDETGEFLCKQGNE 296
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 297 FGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMpDGREVTTTPLAADDWKGVEPIYETMP 376
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYEL-DGEELLTMPATTERWARCEPNFRSFD 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 5542174 377 GWSESTFGVKDRSG---LPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPF 429
Cdd:PRK13785 399 GWPEVDWAAVAEEGydaLPENARTYLEYVSDELDTPIYAVGVGPGREETVVLENPF 454
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
5-426 |
4.10e-91 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 278.69 E-value: 4.10e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLL--TERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 82
Cdd:PRK04293 5 IVVGGFFGDEGKGKIIAYLalKDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLLKE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 83 MKELEdrgipVRERLLLSEACPLILDYHVALDnaREKARGAKAIGTTGRGIGPAYEDKValrgLRVGDLfdketfaeklk 162
Cdd:PRK04293 85 VEELN-----VGGRVFVDYRCGIIEEKHVEED--RSDEHLSKKIGSTGTGCGPANADRV----LRRLKL----------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 163 evmeyhnfqlvnyykaeAVDYqkvlddtmavaDILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 242
Cdd:PRK04293 143 -----------------AKDV-----------EELEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYVTSKD 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 243 TTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEflcKQG-NEFGATTGRRRRTGWLDTVAVRRAVQL 321
Cdd:PRK04293 195 TTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAE---KLGlVEYGTVTGRRRRVGPFDFELARRAARI 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 322 NSLSGFCLTKLDVLDglkevKLCvayrmpdgrevtttplaaddwkgvepiyetmpgwsestFGVKDRSGLPQAALNYIKR 401
Cdd:PRK04293 272 NGATQIAITKLDKLD-----KEA--------------------------------------YGVTEYDKLPPEAKKFIEE 308
|
410 420
....*....|....*....|....*
gi 5542174 402 IEELTGVPIDIISTGPDRTETMILR 426
Cdd:PRK04293 309 IEEELGVPVTLISTGPELEDTIDLR 333
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
8.96e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.17 E-value: 8.96e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 5 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQ-GGHNAGHTlVIN--GEKTVLHLIPSGILREN-VTSIIGNGVVLSPAALM 80
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 81 KEMKELEDRGIPVRERLLLSE-ACPLILDYHValdnaREKARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLFDKETFAE 159
Cdd:NF038379 82 EEIEELEDAGHDVGKRLLIHEqATVIELHKHV-----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 160 KLKEVMEYHnFQLVNYYKAeavdyqkvlddtmavadiltsmvvdvsdllDQARQRGDFVMFEGAQGTLLDIDHGTYPYVT 239
Cdd:NF038379 157 VRDQPWEIA-ERVVDNALY------------------------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 240 SSNTTAGGVATGSGLGPRYVDY--VLGILKAYSTRVGA-----GPFPTEL-FDETGeflckQGNEFGATTGRRRRTGWLD 311
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|.
gi 5542174 312 TVAVRRAVQLN 322
Cdd:NF038379 281 AEQVREAVQAN 291
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-426 |
2.55e-27 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 114.76 E-value: 2.55e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 4 VVVLGTQWGDEGKGKIVDLLTER--AKYVVRYQGGHNAGHTLVIN-GEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 80
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 81 -KEMKELEDRGIPVRERLLLSEACpLILDYHVALDnarekARGAKAIGTTGRGIGPAYEDKVALRGLRVGDLF-DKETFA 158
Cdd:PTZ00351 252 eKEIIQLIDAGIDYRDRLFIGNVC-IVTPYHKLLD-----LLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFnDDETLR 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 159 EKLKEVMEYH--NFQLVNYYKAEAVDY--QKVLDDTMAVADILTSMV--------------------------VDVSDLL 208
Cdd:PTZ00351 326 KRLEKDMDTYlgLLKVKNLSDADVVRLcrEENSDGVVRVPDYVIAFAqakdkveflvklyrdrvrhnpdfparCDVTYEL 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 209 DQARQRGDFVMFEGAQGTLLDIDHGTY-PYVTSSNTTAGGVATGSGLG-PRYVDYVLGILKAY-STRVGAG--------- 276
Cdd:PTZ00351 406 HAAVLRGEKVLLEGPQSYWLSNARTKFwESTTSADTTAAGLLAASQLNfQKFKSVVLNVHKAPgSSRVGIGacpssfvpq 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 277 ----------------------------------PF------------PTELFDETGEF---------LCKQGNEFGATT 301
Cdd:PTZ00351 486 dyfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDYnigvamaiaSAQHHGECGAVT 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542174 302 GRRRRTGWLDTVAVRravQLNSLSGFCLT--KLDVLDGLKEVKLCVAYRM--PDGREVTTT--------------PLAAD 363
Cdd:PTZ00351 566 KKPRVCGFFDCVLQH---EVNSIQGPYLTisALDRGDEYDKVGVTIAYVYynPEGKQVDVNghvykngdiiragdPVPSE 642
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 5542174 364 D-WKGVEPIYETMPGWSESTFGVKDR---SGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILR 426
Cdd:PTZ00351 643 PaLYHCHPIVKLIDGWRDNPIAAAKRrrnAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYLR 709
|
|
| |
