NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|5542184]
View 

Chain A, Protein (cd46)

Protein Classification

CCP domain-containing protein( domain architecture ID 13269523)

CCP domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 65-124 9.18e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.63  E-value: 9.18e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184   65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPICE 124
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
PHA02639 super family cl31493
EEV host range protein; Provisional
 1-123 3.65e-04

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02639:

Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 38.49  E-value: 3.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184     1 CEEPPTFEAMELIGKpKPYYEIGERVDYKCK--KGYFYIPPLATHTICDRNHTWLPvSDDACYRETC--PYIRDP-LNGq 75
Cdd:PHA02639  85 CNDPPSIINGKIYNK-REMYKVGDEIYYVCNehKGVQYSLVGNEKITCIQDKSWKP-DPPICKMINCrfPALQNGyING- 161

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 5542184    76 aVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKgsvAIWSGKPPIC 123
Cdd:PHA02639 162 -IPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNIN---ATWFPSIPTC 205
 
Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 65-124 9.18e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.63  E-value: 9.18e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184   65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPICE 124
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 20-126 1.32e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 62.36  E-value: 1.32e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184    20 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLpvsDDACYRETCPYIRDPLNGQAvpANGTYEFGYQMHFICNEGYYL 99
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTL---FNQCIKRRCPSPRDIDNGQL--DIGGVDFGSSITYSCNSGYQL 118

                         90       100
                 ....*....|....*....|....*....
gi 5542184   100 IGEEILYCEL--KGSVaIWSGKPPICEKV 126
Cdd:PHA02927 119 IGESKSYCELgsTGSM-VWNPEAPICESV 146
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 65-123 1.61e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.23  E-value: 1.61e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 5542184      65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPIC 123
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
65-123 6.67e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 6.67e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 5542184     65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPIC 123
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 1-123 3.65e-04

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 38.49  E-value: 3.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184     1 CEEPPTFEAMELIGKpKPYYEIGERVDYKCK--KGYFYIPPLATHTICDRNHTWLPvSDDACYRETC--PYIRDP-LNGq 75
Cdd:PHA02639  85 CNDPPSIINGKIYNK-REMYKVGDEIYYVCNehKGVQYSLVGNEKITCIQDKSWKP-DPPICKMINCrfPALQNGyING- 161

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 5542184    76 aVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKgsvAIWSGKPPIC 123
Cdd:PHA02639 162 -IPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNIN---ATWFPSIPTC 205
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1-54 4.44e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 35.97  E-value: 4.44e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 5542184       1 CEEPPTFEAMELIGkPKPYYEIGERVDYKCKKGYFYIPPlaTHTICDRNHTWLP 54
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGS--STITCLENGTWSP 51
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1-54 8.09e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 35.13  E-value: 8.09e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 5542184    1 CEEPPTFEAMELIGkPKPYYEIGERVDYKCKKGYFYIPPlaTHTICDRNHTWLP 54
Cdd:cd00033   1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGS--STITCTENGGWSP 51
 
Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 65-124 9.18e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.63  E-value: 9.18e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184   65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPICE 124
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 20-126 1.32e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 62.36  E-value: 1.32e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184    20 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLpvsDDACYRETCPYIRDPLNGQAvpANGTYEFGYQMHFICNEGYYL 99
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTL---FNQCIKRRCPSPRDIDNGQL--DIGGVDFGSSITYSCNSGYQL 118

                         90       100
                 ....*....|....*....|....*....
gi 5542184   100 IGEEILYCEL--KGSVaIWSGKPPICEKV 126
Cdd:PHA02927 119 IGESKSYCELgsTGSM-VWNPEAPICESV 146
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 65-123 1.61e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.23  E-value: 1.61e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 5542184      65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPIC 123
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
65-123 6.67e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 6.67e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 5542184     65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPIC 123
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 20-126 4.72e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 46.97  E-value: 4.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184    20 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNE---- 95
Cdd:PHA02639  40 YEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNKREMYKVGDEIYYVCNEhkgv 119

                         90       100       110
                 ....*....|....*....|....*....|.
gi 5542184    96 GYYLIGEEILYCELKGSvaiWSGKPPICEKV 126
Cdd:PHA02639 120 QYSLVGNEKITCIQDKS---WKPDPPICKMI 147
PHA02639 PHA02639
EEV host range protein; Provisional
 1-123 3.65e-04

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 38.49  E-value: 3.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184     1 CEEPPTFEAMELIGKpKPYYEIGERVDYKCK--KGYFYIPPLATHTICDRNHTWLPvSDDACYRETC--PYIRDP-LNGq 75
Cdd:PHA02639  85 CNDPPSIINGKIYNK-REMYKVGDEIYYVCNehKGVQYSLVGNEKITCIQDKSWKP-DPPICKMINCrfPALQNGyING- 161

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 5542184    76 aVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKgsvAIWSGKPPIC 123
Cdd:PHA02639 162 -IPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNIN---ATWFPSIPTC 205
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1-54 4.44e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 35.97  E-value: 4.44e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 5542184       1 CEEPPTFEAMELIGkPKPYYEIGERVDYKCKKGYFYIPPlaTHTICDRNHTWLP 54
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGS--STITCLENGTWSP 51
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1-54 8.09e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 35.13  E-value: 8.09e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 5542184    1 CEEPPTFEAMELIGkPKPYYEIGERVDYKCKKGYFYIPPlaTHTICDRNHTWLP 54
Cdd:cd00033   1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGS--STITCTENGGWSP 51
PHA02817 PHA02817
EEV Host range protein; Provisional
 1-125 9.76e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 37.23  E-value: 9.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184     1 CEEPPTFEAMELIGKpKPYYEIGERVDYKC---KKGYFYIPPLATHTICDRNHTWLPvSDDACYRETC--PYIRDP-LNG 74
Cdd:PHA02817  24 CCYPPSIKNGYIYNK-KTEYNIGSNVTFFCgnnTRGVRYTLVGEKNIICEKDGKWNK-EFPVCKIIRCrfPALQNGfVNG 101

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 5542184    75 qaVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSvaiWSGKPPICEK 125
Cdd:PHA02817 102 --IPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSS---WIPKVPICSR 147
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 21-126 1.23e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 36.94  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5542184    21 EIGERVDYKCKKGYFYIPplATHTICDRNHT----WLPVSDdACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEG 96
Cdd:PHA02927 103 DFGSSITYSCNSGYQLIG--ESKSYCELGSTgsmvWNPEAP-ICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSG 179

                         90       100       110
                 ....*....|....*....|....*....|
gi 5542184    97 YYLIGEEILYCelkgSVAIWSgKPPICEKV 126
Cdd:PHA02927 180 YSLIGNSGVLC----SGGEWS-DPPTCQIV 204
PHA02639 PHA02639
EEV host range protein; Provisional
 65-123 2.14e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 36.57  E-value: 2.14e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 5542184    65 CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPIC 123
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFC 80
PHA02817 PHA02817
EEV Host range protein; Provisional
 60-126 3.24e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 35.69  E-value: 3.24e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 5542184    60 CYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEG-----YYLIGEEILYCELKGSvaiWSGKPPICEKV 126
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK---WNKEFPVCKII 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH