NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|568931102|ref|XP_006538864|]
View 

rootletin isoform X1 [Mus musculus]

Protein Classification

Rootletin and Smc domain-containing protein( domain architecture ID 13865873)

protein containing domains Rootletin, COG4372, Smc, and SMC_prok_B

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
84-260 2.14e-50

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 177.15  E-value: 2.14e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    84 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRL-------------RDTEHSQDLDSALLRL 150
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   151 EEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQ 230
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 568931102   231 VMGLRRQASEVKMGTERDLLQLGGELVRTS 260
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 457-984 3.59e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 120.81  E-value: 3.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  457 KRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLT 536
Cdd:COG1196   222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  537 HSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREAL 616
Cdd:COG1196   302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  617 SCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVAL 696
Cdd:COG1196   382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  697 LGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQE 776
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  777 LEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQ 856
Cdd:COG1196   542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  857 LEADS--QALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWR 934
Cdd:COG1196   622 LLGRTlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 568931102  935 ELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAE 984
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 919-1720 3.45e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.75  E-value: 3.45e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   919 EEDLQRLQHEKEAA--WRELQAERAQLQGQLQQEReelLARMEAEKEELSKEIAALQQERDEgLLLAESEKQQALSLKES 996
Cdd:TIGR02168  199 ERQLKSLERQAEKAerYKELKAELRELELALLVLR---LEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   997 EKTALSEK---LMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLG 1073
Cdd:TIGR02168  275 EVSELEEEieeLQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1074 RQREacmrEAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAV 1153
Cdd:TIGR02168  355 SLEA----ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1154 KKAESERISLKLANEDKEQKLALLEEARVsvakeagelRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADL 1233
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEELQEELERL---------EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1234 QGrLALGERTEKESRREALGLRQRLLKGESSLEALKQELqgsqrklqeqEAEFRARERGLLG-SLEEARGA----EKRLL 1308
Cdd:TIGR02168  502 EG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAI----------EAALGGRLQAVVVeNLNAAKKAiaflKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1309 DSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGG 1388
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1389 SGDGLSSPspleysprsqppspGLIA-SPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERdh 1467
Cdd:TIGR02168  651 DGDLVRPG--------------GVITgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL-- 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1468 aasrakqlqkavaeseeawRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKA 1547
Cdd:TIGR02168  715 -------------------EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1548 TEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVE 1627
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1628 RLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLG 1707
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          810
                   ....*....|...
gi 568931102  1708 EQVQTLRGELASL 1720
Cdd:TIGR02168  936 VRIDNLQERLSEE 948
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1544-1906 4.31e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 4.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1544 KMKATEAKLEsdkrRLKEVLDASESRSIKLELQRRALE--GELQRSRlglgdREAHAQALQDRVDSLQRQVADSEVKAGT 1621
Cdd:COG1196   180 KLEATEENLE----RLEDILGELERQLEPLERQAEKAEryRELKEEL-----KELEAELLLLKLRELEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1622 LQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARR 1701
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1702 QSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKR 1781
Cdd:COG1196   331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1782 DLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEgnhnpv 1861
Cdd:COG1196   411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE------ 484

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 568931102 1862 QPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEE 1906
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
84-260 2.14e-50

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 177.15  E-value: 2.14e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    84 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRL-------------RDTEHSQDLDSALLRL 150
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   151 EEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQ 230
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 568931102   231 VMGLRRQASEVKMGTERDLLQLGGELVRTS 260
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 457-984 3.59e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 120.81  E-value: 3.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  457 KRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLT 536
Cdd:COG1196   222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  537 HSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREAL 616
Cdd:COG1196   302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  617 SCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVAL 696
Cdd:COG1196   382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  697 LGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQE 776
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  777 LEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQ 856
Cdd:COG1196   542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  857 LEADS--QALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWR 934
Cdd:COG1196   622 LLGRTlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 568931102  935 ELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAE 984
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 519-1238 9.02e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 116.69  E-value: 9.02e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   519 QRLRSANELLSREKGNLthslqvtqqqaKELRQELEKLQA---AQEELKRQHNQLEDAQED-SVQEGARARRELERSHRQ 594
Cdd:TIGR02168  179 RKLERTRENLDRLEDIL-----------NELERQLKSLERqaeKAERYKELKAELRELELAlLVLRLEELREELEELQEE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   595 LEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNES 674
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   675 LAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRS 754
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   755 ERSHLQEQLAQLSRQLSGRDQEL-EQALRESQRQVE----ALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRL 829
Cdd:TIGR02168  408 RLERLEDRRERLQQEIEELLKKLeEAELKELQAELEeleeELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   830 RLEKEALES---SLFDVQRQLAQLEARREQLEADSQALL----------LAKETLTGElaGLRQQVTSTEEKAALDKELM 896
Cdd:TIGR02168  488 QARLDSLERlqeNLEGFSEGVKALLKNQSGLSGILGVLSelisvdegyeAAIEAALGG--RLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   897 TQKL----------VQAEREAQASLREQRAAHEEDL---------------------------------QRLQHEKEAAW 933
Cdd:TIGR02168  566 KQNElgrvtflpldSIKGTEIQGNDREILKNIEGFLgvakdlvkfdpklrkalsyllggvlvvddldnaLELAKKLRPGY 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   934 R--------------ELQAERAQLQGQLQQEREelLARMEAEKEELSKEIAALQQERDEgLLLAESEKQQALSLKESEKT 999
Cdd:TIGR02168  646 RivtldgdlvrpggvITGGSAKTNSSILERRRE--IEELEEKIEELEEKIAELEKALAE-LRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1000 ALSEKLMGTRHSLAAISLEmERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREAC 1079
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAE-VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1080 MREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESE 1159
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE 881

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102  1160 RislklanedkeqklALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLA 1238
Cdd:TIGR02168  882 R--------------ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 919-1720 3.45e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.75  E-value: 3.45e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   919 EEDLQRLQHEKEAA--WRELQAERAQLQGQLQQEReelLARMEAEKEELSKEIAALQQERDEgLLLAESEKQQALSLKES 996
Cdd:TIGR02168  199 ERQLKSLERQAEKAerYKELKAELRELELALLVLR---LEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   997 EKTALSEK---LMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLG 1073
Cdd:TIGR02168  275 EVSELEEEieeLQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1074 RQREacmrEAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAV 1153
Cdd:TIGR02168  355 SLEA----ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1154 KKAESERISLKLANEDKEQKLALLEEARVsvakeagelRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADL 1233
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEELQEELERL---------EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1234 QGrLALGERTEKESRREALGLRQRLLKGESSLEALKQELqgsqrklqeqEAEFRARERGLLG-SLEEARGA----EKRLL 1308
Cdd:TIGR02168  502 EG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAI----------EAALGGRLQAVVVeNLNAAKKAiaflKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1309 DSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGG 1388
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1389 SGDGLSSPspleysprsqppspGLIA-SPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERdh 1467
Cdd:TIGR02168  651 DGDLVRPG--------------GVITgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL-- 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1468 aasrakqlqkavaeseeawRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKA 1547
Cdd:TIGR02168  715 -------------------EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1548 TEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVE 1627
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1628 RLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLG 1707
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          810
                   ....*....|...
gi 568931102  1708 EQVQTLRGELASL 1720
Cdd:TIGR02168  936 VRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1020-1613 1.75e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.32  E-value: 1.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1020 ERQKRDAQSRQEqdrntlnaLTSELRDLRAQLeeataaHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDG 1099
Cdd:COG1196   206 ERQAEKAERYRE--------LKEELKELEAEL------LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1100 LRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEE 1179
Cdd:COG1196   272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1180 ARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLL 1259
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1260 KGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRL------LDSARSLELRLEAVRAETSELGLRLS 1333
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALaelleeLAEAAARLLLLLEAEADYEGFLEGVK 511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1334 AAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLeysprsqpPSPGLI 1413
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--------PLDKIR 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1414 ASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRL 1493
Cdd:COG1196   584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1494 SGAQAELALQEESVRRSKREcratldQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKL 1573
Cdd:COG1196   664 GGSRRELLAALLEAEAELEE------LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 568931102 1574 ELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVA 1613
Cdd:COG1196   738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 15-857 1.67e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 1.67e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    15 QQELSRVEDLLAQSRAERD------ELAIKYNAVNERLEQA-VRLETGELEA---------QEPRGLVRQSVELRRQLQE 78
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELeLALLVLRLEElreeleelqEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    79 EQSSY----------RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALL 148
Cdd:TIGR02168  265 LEEKLeelrlevselEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   149 RLEEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWtrscKELEQREAVWRREEESFNTYFSSEHSRLLRLW 228
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQLELQIASLNNEIERLEARLERLEDRRERLQ 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   229 RQVMGLRRQASEVKMgterdllqlggelvrtsRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKD 308
Cdd:TIGR02168  421 QEIEELLKKLEEAEL-----------------KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   309 LAQLQVQSDLDKaDLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLdtedGEGLQQTLRDLAQAA 388
Cdd:TIGR02168  484 LAQLQARLDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAAL----GGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   389 LSDTESGVQLSSSERTAdtsdGSLRGFSGQRTPTPPRHSPGRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGR 468
Cdd:TIGR02168  559 KKAIAFLKQNELGRVTF----LPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   469 YEASQELLGSVRKQLSDSEGERRGleeqlqrlrdqtaaSAQAQEDAQREAQRLRSANELLsrekgNLTHSLQVTQQQAKE 548
Cdd:TIGR02168  635 LELAKKLRPGYRIVTLDGDLVRPG--------------GVITGGSAKTNSSILERRREIE-----ELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   549 LRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQT 628
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   629 EKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLskmSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATt 708
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL---TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS- 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   709 mavEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLaqlsRQLSGRDQELEQALRESQrqv 788
Cdd:TIGR02168  852 ---EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL----RELESKRSELRRELEELR--- 921

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102   789 EALERAAREKEAMAKERAGLAVKLAAaerEGRTLSEEAIRLRLEKEALESSLfdvQRQLAQLEARREQL 857
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSE---EYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 451-1208 2.44e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.51  E-value: 2.44e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  451 IHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEG--ERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELl 528
Cdd:PTZ00121 1055 NHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEAteEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA- 1133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  529 srekgnlthslqvtqQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEqleVKRSGLTKE 608
Cdd:PTZ00121 1134 ---------------RKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE---VRKAEELRK 1195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  609 LVEVREAlSCAILQRDVLQTEKAEVAEALTKAEAGRaqlelsltklRAEEASLRDSlskmsalnESLAQDKLELNRLIAQ 688
Cdd:PTZ00121 1196 AEDARKA-EAARKAEEERKAEEARKAEDAKKAEAVK----------KAEEAKKDAE--------EAKKAEEERNNEEIRK 1256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  689 LEEEKVALLGRQQQAEHAttmavEKQELLEQLRLEQEVERqglqgslcvAEQAREALEQQilvlRSERSHLQEQLAQLSR 768
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKA-----EEARKADELKKAEEKKK---------ADEAKKAEEKK----KADEAKKKAEEAKKAD 1318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  769 QLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGlavKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQR-QL 847
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD---EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKaDE 1395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  848 AQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEE--KAALDKELMTQKLVQAEREAQASLREQRAaheEDLQRL 925
Cdd:PTZ00121 1396 AKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKAEEAKKKA---EEAKKA 1472

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  926 QHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAEsEKQQALSLKESEKTALSEKL 1005
Cdd:PTZ00121 1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEEKKKADEL 1551

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1006 MGTRHSLAAisleMERQKRDAQSRQEQDRNTLNALTSELRDL---------------------RAQLEEATAAHAQTVKE 1064
Cdd:PTZ00121 1552 KKAEELKKA----EEKKKAEEAKKAEEDKNMALRKAEEAKKAeearieevmklyeeekkmkaeEAKKAEEAKIKAEELKK 1627

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1065 LEE---RTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREA 1141
Cdd:PTZ00121 1628 AEEekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1142 LRRSNEELRSA--VKKAESER-ISLKLANEDKEQKLALLEEARVSvAKEAGELRASLQEVERSRLEARRE 1208
Cdd:PTZ00121 1708 KKKEAEEKKKAeeLKKAEEENkIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKE 1776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 15-609 1.18e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 1.18e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   15 QQELSRVEDLLAQSRAERDEL------AIKYNAVNERLEQAvrletgeleaqeprgLVRQSVELRRQLQEEQSSYRRKLQ 88
Cdd:COG1196   185 EENLERLEDILGELERQLEPLerqaekAERYRELKEELKEL---------------EAELLLLKLRELEAELEELEAELE 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   89 AYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEEEQQRSASLAQVNAMLR 168
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  169 EQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESfntyFSSEHSRLLRLWRQVMGLRRQASEVKMGTERD 248
Cdd:COG1196   330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE----LAEAEEELEELAEELLEALRAAAELAAQLEEL 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  249 LLQLGGELVRTSRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVT 328
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  329 ELALSVEHLQNQNSEKDQ----------VNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQL 398
Cdd:COG1196   486 LAEAAARLLLLLEAEADYegflegvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  399 SSSERTADTSDGSLRGFSGQRTPTPPRHSPGRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGS 478
Cdd:COG1196   566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  479 VRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQA 558
Cdd:COG1196   646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568931102  559 AQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKEL 609
Cdd:COG1196   726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
PTZ00121 PTZ00121
MAEBL; Provisional
 753-1357 4.15e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.10  E-value: 4.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  753 RSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAERegrtlSEEAIRLRLE 832
Cdd:PTZ00121 1071 GLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARK-----AEDARKAEEA 1145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  833 KEALESSLFDVQRQLAqlEARREQLEADsqalllAKETLTGELAGLRQQVTSTEE--KAALDKELMTQKLVQAEREAQAS 910
Cdd:PTZ00121 1146 RKAEDAKRVEIARKAE--DARKAEEARK------AEDAKKAEAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEA 1217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  911 LREQRAAHEEDLQRLQhekEAAWRELQAERAQLQGQLQQEREELLARMeAEKEELSKEIAALQQERDEGLLLAEsEKQQA 990
Cdd:PTZ00121 1218 RKAEDAKKAEAVKKAE---EAKKDAEEAKKAEEERNNEEIRKFEEARM-AHFARRQAAIKAEEARKADELKKAE-EKKKA 1292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  991 LSLKESEKTALSEKLMGtrhslaaiSLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELE---E 1067
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKK--------KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEaaeE 1364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1068 RTGNLGRQREACMREAEELRTQLRVLEDTRDGLRREllEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNE 1147
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA--EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1148 ELRS--AVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGR 1225
Cdd:PTZ00121 1443 AKKAdeAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAK 1522

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1226 LGRELADLQGRLALGERTEKESRREALGLRQrllkgESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEK 1305
Cdd:PTZ00121 1523 KADEAKKAEEAKKADEAKKAEEKKKADELKK-----AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568931102 1306 RLLDSARSLELRLEAVRAETSEL-GLRLSAAEGRAQGLEVELARVEAQRRVAE 1357
Cdd:PTZ00121 1598 MKLYEEEKKMKAEEAKKAEEAKIkAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1544-1906 4.31e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 4.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1544 KMKATEAKLEsdkrRLKEVLDASESRSIKLELQRRALE--GELQRSRlglgdREAHAQALQDRVDSLQRQVADSEVKAGT 1621
Cdd:COG1196   180 KLEATEENLE----RLEDILGELERQLEPLERQAEKAEryRELKEEL-----KELEAELLLLKLRELEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1622 LQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARR 1701
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1702 QSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKR 1781
Cdd:COG1196   331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1782 DLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEgnhnpv 1861
Cdd:COG1196   411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE------ 484

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 568931102 1862 QPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEE 1906
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 519-1157 1.05e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.53  E-value: 1.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   519 QRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEklqaAQEELKRQHNQLEDAQEDSVQ------EGARARRE--LER 590
Cdd:pfam15921   92 RRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERD----AMADIRRRESQSQEDLRNQLQntvhelEAAKCLKEdmLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   591 SHRQLEQLE---VKRSGLTKE----LVEVREALSCAILQRDVLQT-EKAEVAEALTKAeagRAQLELSLTKLRAEEASLR 662
Cdd:pfam15921  168 SNTQIEQLRkmmLSHEGVLQEirsiLVDFEEASGKKIYEHDSMSTmHFRSLGSAISKI---LRELDTEISYLKGRIFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   663 DSLSKMsalnESLAQDKLEL------NRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLR--------------- 721
Cdd:pfam15921  245 DQLEAL----KSESQNKIELllqqhqDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQeqarnqnsmymrqls 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   722 -LEQEVE--RQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREK 798
Cdd:pfam15921  321 dLESTVSqlRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQN 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   799 EAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALES------------------SLFDVQRQLAQLEARREQLEAD 860
Cdd:pfam15921  401 KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgqmerqmaaiqgkneSLEKVSSLTAQLESTKEMLRKV 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   861 SQALLLAKETLTGELAGLRQQVTSTEEK---------------AALDKELMTQKLVQAE----REAQA---SLREQRAAH 918
Cdd:pfam15921  481 VEELTAKKMTLESSERTVSDLTASLQEKeraieatnaeitklrSRVDLKLQELQHLKNEgdhlRNVQTeceALKLQMAEK 560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   919 EEDLQRLQHEKEAAWR----------ELQAERAQLQGQLQQEREELLA------RMEAEKEELSKEIAALQQERDEgLLL 982
Cdd:pfam15921  561 DKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEKEINDRRLELQEfkilkdKKDAKIRELEARVSDLELEKVK-LVN 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   983 AESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATaahaQTV 1062
Cdd:pfam15921  640 AGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR----NTL 715

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1063 KELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREAL 1142
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVL 795

                          730
                   ....*....|....*
gi 568931102  1143 RRSNEELRSAVKKAE 1157
Cdd:pfam15921  796 RSQERRLKEKVANME 810
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 701-1348 7.18e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.93  E-value: 7.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   701 QQAEHATTMAVEKQEL------LEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVL---RSERSHL-QEQLAQLSRQL 770
Cdd:pfam12128  277 RQEERQETSAELNQLLrtlddqWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFldaDIETAAAdQEQLPSWQSEL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   771 SGRDQELEqALRESQRQVEAL--ERAAREKEAMAKERAGLAVKLAAaEREGRTLSEEAIRLRLEkeALESSLFDvQRQLA 848
Cdd:pfam12128  357 ENLEERLK-ALTGKHQDVTAKynRRRSKIKEQNNRDIAGIKDKLAK-IREARDRQLAVAEDDLQ--ALESELRE-QLEAG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   849 QLEARREQLEADSQAlllaketltGELAGLRQQVTSTEEKaaLDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHE 928
Cdd:pfam12128  432 KLEFNEEEYRLKSRL---------GELKLRLNQATATPEL--LLQLENFDERIERAREEQEAANAEVERLQSELRQARKR 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   929 KEAAWRELQAERA---QLQGQLQQEREELLARMEAEKEELSKEIAALQQerDEGLLLAesekqQALSLKESEKTALSEKL 1005
Cdd:pfam12128  501 RDQASEALRQASRrleERQSALDELELQLFPQAGTLLHFLRKEAPDWEQ--SIGKVIS-----PELLHRTDLDPEVWDGS 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1006 MGTRHSLAAISLEMERQkrdaqsrqeqDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEE 1085
Cdd:pfam12128  574 VGGELNLYGVKLDLKRI----------DVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETF 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1086 LRTqlrVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLsegAKEREALRRSNEELRSAVKKAESErislkl 1165
Cdd:pfam12128  644 ART---ALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSL---EAQLKQLDKKHQAWLEEQKEQKRE------ 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1166 ANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRElqELRRQMKTLDSDN---GRLGRELADLQGRLALGER 1242
Cdd:pfam12128  712 ARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALET--WYKRDLASLGVDPdviAKLKREIRTLERKIERIAV 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1243 TEKESRR-------EALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLE 1315
Cdd:pfam12128  790 RRQEVLRyfdwyqeTWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869

                          650       660       670
                   ....*....|....*....|....*....|...
gi 568931102  1316 LRLEAVRAETSELGLRLSAAEGRAQGLEVELAR 1348
Cdd:pfam12128  870 SKLATLKEDANSEQAQGSIGERLAQLEDLKLKR 902
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1671-1916 1.57e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1671 LQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALR 1750
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1751 SVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVE--REKLRSHEDTLR-----LNAERG 1823
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEeqLETLRSKVAQLElqiasLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1824 RLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLrsaqVQTERTLEARERAHRQRVSG 1903
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERL----EEALEELREELEEAEQALDA 479

                          250
                   ....*....|...
gi 568931102  1904 LEEQVSTLKAQLH 1916
Cdd:TIGR02168  480 AERELAQLQARLD 492
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 780-1076 7.99e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.83  E-value: 7.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  780 ALRESQRQVEALERAAREKEAMAKeraglavklAAAEREgrtlSEEAIRLRLEKEAlesslfdvQRQLAQLEARREQLEA 859
Cdd:NF012221 1536 ATSESSQQADAVSKHAKQDDAAQN---------ALADKE----RAEADRQRLEQEK--------QQQLAAISGSQSQLES 1594

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  860 DSQALLlaketltgELAGLRQQVTSTEEKAALDKEL--MTQKLVQAEREAQAS------LREQRAahEEDLQRLQHE--- 928
Cdd:NF012221 1595 TDQNAL--------ETNGQAQRDAILEESRAVTKELttLAQGLDALDSQATYAgesgdqWRNPFA--GGLLDRVQEQldd 1664

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  929 -KEAAWRELQAERAQLQGQLQQEREElLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKlmg 1007
Cdd:NF012221 1665 aKKISGKQLADAKQRHVDNQQKVKDA-VAKSEAGVAQGEQNQANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDA--- 1740

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102 1008 trHSLAaislemerqkRDAQSRQEQDrntlnALTSELRDLRAQleeataAHAQTVKELEERTGNlgRQR 1076
Cdd:NF012221 1741 --NAAA----------NDAQSRGEQD-----ASAAENKANQAQ------ADAKGAKQDESDKPN--RQG 1784
growth_prot_Scy NF041483
polarized growth protein Scy;
687-1211 2.30e-03

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 43.28  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  687 AQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEverQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQL 766
Cdd:NF041483  183 ARAEAERLAEEARQRLGSEAESARAEAEAILRRARKDAE---RLLNAASTQAQEATDHAEQLRSSTAAESDQARRQAAEL 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  767 SRQLSGRDQELEQALRESQRQVEALEraarekeAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSlfdvqrq 846
Cdd:NF041483  260 SRAAEQRMQEAEEALREARAEAEKVV-------AEAKEAAAKQLASAESANEQRTRTAKEEIARLVGEATKEA------- 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  847 lAQLEARREQLEADSQAlllAKETLTGELAGLRQQVTSTEEKAALDKELMTQK--LVQAEREAQASLReqraAHEEDLQR 924
Cdd:NF041483  326 -EALKAEAEQALADARA---EAEKLVAEAAEKARTVAAEDTAAQLAKAARTAEevLTKASEDAKATTR----AAAEEAER 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  925 LQHEKEAAWRELQAERA----QLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGL-----LLAESEKQQALSLKE 995
Cdd:NF041483  398 IRREAEAEADRLRGEAAdqaeQLKGAAKDDTKEYRAKTVELQEEARRLRGEAEQLRAEAVaegerIRGEARREAVQQIEE 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  996 SEKTA---LSEKLMGTRHSLAAISLEMERQKRDAQSR----QEQDRNTLNALTSELRDLRAQLEE-ATAAHAQTVKELEE 1067
Cdd:NF041483  478 AARTAeelLTKAKADADELRSTATAESERVRTEAIERattlRRQAEETLERTRAEAERLRAEAEEqAEEVRAAAERAARE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1068 RTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELL-----EAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREAL 1142
Cdd:NF041483  558 LREETERAIAARQAEAAEELTRLHTEAEERLTAAEEALadaraEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAER 637

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102 1143 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQE 1211
Cdd:NF041483  638 LRTEAAADASAARAEGENVAVRLRSEAAAEAERLKSEAQESADRVRAEAAAAAERVGTEAAEALAAAQE 706
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
84-260 2.14e-50

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 177.15  E-value: 2.14e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    84 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRL-------------RDTEHSQDLDSALLRL 150
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   151 EEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQ 230
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 568931102   231 VMGLRRQASEVKMGTERDLLQLGGELVRTS 260
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 457-984 3.59e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 120.81  E-value: 3.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  457 KRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLT 536
Cdd:COG1196   222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  537 HSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREAL 616
Cdd:COG1196   302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  617 SCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVAL 696
Cdd:COG1196   382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  697 LGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQE 776
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  777 LEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQ 856
Cdd:COG1196   542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  857 LEADS--QALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWR 934
Cdd:COG1196   622 LLGRTlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 568931102  935 ELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAE 984
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 454-978 5.67e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 116.96  E-value: 5.67e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  454 ALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKG 533
Cdd:COG1196   261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  534 NLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVR 613
Cdd:COG1196   341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  614 EALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLskmsalnESLAQDKLELNRLIAQLEEEK 693
Cdd:COG1196   421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA-------ALLEAALAELLEELAEAAARL 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  694 VALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGR 773
Cdd:COG1196   494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  774 DQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEAR 853
Cdd:COG1196   574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  854 REQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAW 933
Cdd:COG1196   654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*
gi 568931102  934 RELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDE 978
Cdd:COG1196   734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 519-1238 9.02e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 116.69  E-value: 9.02e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   519 QRLRSANELLSREKGNLthslqvtqqqaKELRQELEKLQA---AQEELKRQHNQLEDAQED-SVQEGARARRELERSHRQ 594
Cdd:TIGR02168  179 RKLERTRENLDRLEDIL-----------NELERQLKSLERqaeKAERYKELKAELRELELAlLVLRLEELREELEELQEE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   595 LEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNES 674
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   675 LAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRS 754
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   755 ERSHLQEQLAQLSRQLSGRDQEL-EQALRESQRQVE----ALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRL 829
Cdd:TIGR02168  408 RLERLEDRRERLQQEIEELLKKLeEAELKELQAELEeleeELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   830 RLEKEALES---SLFDVQRQLAQLEARREQLEADSQALL----------LAKETLTGElaGLRQQVTSTEEKAALDKELM 896
Cdd:TIGR02168  488 QARLDSLERlqeNLEGFSEGVKALLKNQSGLSGILGVLSelisvdegyeAAIEAALGG--RLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   897 TQKL----------VQAEREAQASLREQRAAHEEDL---------------------------------QRLQHEKEAAW 933
Cdd:TIGR02168  566 KQNElgrvtflpldSIKGTEIQGNDREILKNIEGFLgvakdlvkfdpklrkalsyllggvlvvddldnaLELAKKLRPGY 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   934 R--------------ELQAERAQLQGQLQQEREelLARMEAEKEELSKEIAALQQERDEgLLLAESEKQQALSLKESEKT 999
Cdd:TIGR02168  646 RivtldgdlvrpggvITGGSAKTNSSILERRRE--IEELEEKIEELEEKIAELEKALAE-LRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1000 ALSEKLMGTRHSLAAISLEmERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREAC 1079
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAE-VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1080 MREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESE 1159
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE 881

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102  1160 RislklanedkeqklALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLA 1238
Cdd:TIGR02168  882 R--------------ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 460-1219 1.20e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 112.84  E-value: 1.20e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   460 LQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSL 539
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   540 QVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCA 619
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   620 ILQRDVLQTEkaevaeaLTKAEAGRAQLELSLTKLRAEEASLRDSLS--KMSALNESLAQDKLELNRLIAQLEEEKVALL 697
Cdd:TIGR02168  392 ELQIASLNNE-------IERLEARLERLEDRRERLQQEIEELLKKLEeaELKELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   698 GRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQilvlrSERSHLQEQLAQLSRQLSGRDQEL 777
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ-----SGLSGILGVLSELISVDEGYEAAI 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   778 EQALRESQRQ--VEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEArre 855
Cdd:TIGR02168  540 EAALGGRLQAvvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRK--- 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   856 qLEADSQALLLAKETLTGELAgLRQQVTSTEEKAALDKELMTQK--LVQAEREAQASLREQRAAHEEdLQRLQHEKEAAW 933
Cdd:TIGR02168  617 -ALSYLLGGVLVVDDLDNALE-LAKKLRPGYRIVTLDGDLVRPGgvITGGSAKTNSSILERRREIEE-LEEKIEELEEKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   934 RELQAERAQLQGQLqQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKE--SEKTALSEKLMGTRHS 1011
Cdd:TIGR02168  694 AELEKALAELRKEL-EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKelTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1012 LAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEataaHAQTVKELEERTGNLGRQREACMREAEELRTQLR 1091
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL----LNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1092 VLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKE 1171
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102  1172 QKLA--------LLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTL 1219
Cdd:TIGR02168  929 LRLEglevridnLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 493-1067 4.91e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.33  E-value: 4.91e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  493 LEEQLQRLRDQ--TAASAQAQEDAQREAQ---------RLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQE 561
Cdd:COG1196   198 LERQLEPLERQaeKAERYRELKEELKELEaellllklrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  562 ELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAE 641
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  642 AGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLR 721
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  722 LEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLsgrDQELEQALRESQRQVEALERAAREKEAM 801
Cdd:COG1196   438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL---AEAAARLLLLLEAEADYEGFLEGVKAAL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  802 AKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQ 881
Cdd:COG1196   515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALAR 594

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  882 VTSTEEKAALDKELmtQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAE 961
Cdd:COG1196   595 GAIGAAVDLVASDL--READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  962 KEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALT 1041
Cdd:COG1196   673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                         570       580
                  ....*....|....*....|....*.
gi 568931102 1042 SELRDLRAQLEEATAAHAQTVKELEE 1067
Cdd:COG1196   753 LEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 717-1253 8.38e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.56  E-value: 8.38e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  717 LEQLRLEQEVERQGLQGSLCVAEQARE---ALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALER 793
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAelaELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  794 AAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTG 873
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  874 ELAGLRQQVTSTEEKAALDKELMTQKL-----VQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQ 948
Cdd:COG1196   394 AAAELAAQLEELEEAEEALLERLERLEeeleeLEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  949 QEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQS 1028
Cdd:COG1196   474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVV 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1029 RQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQ 1108
Cdd:COG1196   554 EDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1109 RKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISL-KLANEDKEQKLALLEEARVSVAKE 1187
Cdd:COG1196   634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLaEEELELEEALLAEEEEERELAEAE 713

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568931102 1188 AGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEK-ESRREALG 1253
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERlEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 919-1720 3.45e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.75  E-value: 3.45e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   919 EEDLQRLQHEKEAA--WRELQAERAQLQGQLQQEReelLARMEAEKEELSKEIAALQQERDEgLLLAESEKQQALSLKES 996
Cdd:TIGR02168  199 ERQLKSLERQAEKAerYKELKAELRELELALLVLR---LEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   997 EKTALSEK---LMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLG 1073
Cdd:TIGR02168  275 EVSELEEEieeLQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1074 RQREacmrEAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAV 1153
Cdd:TIGR02168  355 SLEA----ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1154 KKAESERISLKLANEDKEQKLALLEEARVsvakeagelRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADL 1233
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEELQEELERL---------EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1234 QGrLALGERTEKESRREALGLRQRLLKGESSLEALKQELqgsqrklqeqEAEFRARERGLLG-SLEEARGA----EKRLL 1308
Cdd:TIGR02168  502 EG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAI----------EAALGGRLQAVVVeNLNAAKKAiaflKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1309 DSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGG 1388
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1389 SGDGLSSPspleysprsqppspGLIA-SPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERdh 1467
Cdd:TIGR02168  651 DGDLVRPG--------------GVITgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL-- 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1468 aasrakqlqkavaeseeawRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKA 1547
Cdd:TIGR02168  715 -------------------EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1548 TEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVE 1627
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1628 RLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLG 1707
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          810
                   ....*....|...
gi 568931102  1708 EQVQTLRGELASL 1720
Cdd:TIGR02168  936 VRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1020-1613 1.75e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.32  E-value: 1.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1020 ERQKRDAQSRQEqdrntlnaLTSELRDLRAQLeeataaHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDG 1099
Cdd:COG1196   206 ERQAEKAERYRE--------LKEELKELEAEL------LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1100 LRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEE 1179
Cdd:COG1196   272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1180 ARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLL 1259
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1260 KGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRL------LDSARSLELRLEAVRAETSELGLRLS 1333
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALaelleeLAEAAARLLLLLEAEADYEGFLEGVK 511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1334 AAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLeysprsqpPSPGLI 1413
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--------PLDKIR 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1414 ASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRL 1493
Cdd:COG1196   584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1494 SGAQAELALQEESVRRSKREcratldQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKL 1573
Cdd:COG1196   664 GGSRRELLAALLEAEAELEE------LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 568931102 1574 ELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVA 1613
Cdd:COG1196   738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 824-1369 1.72e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  824 EEAIRLRLEKEALESSLFdvQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLvQA 903
Cdd:COG1196   213 ERYRELKEELKELEAELL--LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ-AE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  904 EREAQASLREQRAAHEEDLQRLQHEKEAAwRELQAERAQLQGQLQQEREElLARMEAEKEELSKEIAALQQERDEGLLLA 983
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERL-EELEEELAELEEELEELEEE-LEELEEELEEAEEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  984 ESEKQQALSLKESEKTALSEKLMGTRHSLAAIS-----LEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAH 1058
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAqleelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1059 AQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGL--RRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGA 1136
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAaaRLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1137 ------KEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQ 1210
Cdd:COG1196   528 vligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1211 ELRRQMKTLDSDNGRLGRELADLQGRLALGE-RTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRAR 1289
Cdd:COG1196   608 LREADARYYVLGDTLLGRTLVAARLEAALRRaVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1290 ERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRR 1369
Cdd:COG1196   688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 680-1367 6.73e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 6.73e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   680 LELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQ---EVERQGLQGSLCVAEQAREALEQQILVLRSER 756
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVselEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   757 SHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRlekeal 836
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR------ 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   837 eSSLFDVQRQLAQLEARREQLEADsqalllaKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRA 916
Cdd:TIGR02168  386 -SKVAQLELQIASLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   917 AHEEDLQRLQHEKEAAWRELQAERAQLQgQLQQeREELLARMEAEKEELSKEIAALQQERdEGLLLAESEKQQALSLKES 996
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELA-QLQA-RLDSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   997 EKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSelrdlraqleeataahaQTVKELEERTGNLGRQR 1076
Cdd:TIGR02168  535 YEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDS-----------------IKGTEIQGNDREILKNI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1077 EACMREAEELRTQLRVLEDTRDGLRRELLEAQRKgrdsqdsseahrQEASELRRSLSEGA----KEREALRRsneelRSA 1152
Cdd:TIGR02168  598 EGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL------------DNALELAKKLRPGYrivtLDGDLVRP-----GGV 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1153 VKKAESERISLKLAnedKEQKLALLEEARVSVAKEAGELRASLQEVERSRLE-------ARRELQELRRQMKTLDSDNGR 1225
Cdd:TIGR02168  661 ITGGSAKTNSSILE---RRREIEELEEKIEELEEKIAELEKALAELRKELEEleeeleqLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1226 LGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERgllgSLEEARGAEK 1305
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE----ALDELRAELT 813

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568931102  1306 RLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSAL 1367
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL 875
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1043-1879 1.39e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 1.39e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1043 ELRDLRAQLEEATAA-HAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAH 1121
Cdd:TIGR02168  214 RYKELKAELRELELAlLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1122 RQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERS 1201
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1202 RLEARRELQELRR-------QMKTLDSDNGRLGRELADLQGRLA-LGERTEKESRREALGLRQRLLKGESSLEALKQELQ 1273
Cdd:TIGR02168  374 LEELEEQLETLRSkvaqlelQIASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1274 GSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEV--ELARVEA 1351
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlsELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1352 QRRVA-EAQLGGLRSALRRglglgrVSSSPAREAPAGGSGDGLSSPSPLEYSprsqppspglIASPAPPDLDPEAVRDAL 1430
Cdd:TIGR02168  534 GYEAAiEAALGGRLQAVVV------ENLNAAKKAIAFLKQNELGRVTFLPLD----------SIKGTEIQGNDREILKNI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1431 RDFLQELRSAQRERDELKVQTSTLSQQLVeMEAERDHAASRAKQLQK--AVAESEEAWRSADRRLSGAQAELALQEESVR 1508
Cdd:TIGR02168  598 EGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLDNALELAKKLRPgyRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1509 RSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRlkevldasesrsiklelqrralegELQRSR 1588
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR------------------------QISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1589 LGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKN 1668
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1669 LHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRgdaegqlqqlqqalrqrqegeama 1748
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI------------------------ 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1749 lrsvQKLQEERRLLQERLGSLQRALAQLEAEKRDLERsalqfdkdrvalrkTLDKVEREKLRSHEDTLRLNAERGRLDRT 1828
Cdd:TIGR02168  869 ----EELESELEALLNERASLEEALALLRSELEELSE--------------ELRELESKRSELRRELEELREKLAQLELR 930

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568931102  1829 LTGAELDLAEAQQQI---QHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERL 1879
Cdd:TIGR02168  931 LEGLEVRIDNLQERLseeYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 15-857 1.67e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 1.67e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    15 QQELSRVEDLLAQSRAERD------ELAIKYNAVNERLEQA-VRLETGELEA---------QEPRGLVRQSVELRRQLQE 78
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELeLALLVLRLEElreeleelqEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    79 EQSSY----------RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALL 148
Cdd:TIGR02168  265 LEEKLeelrlevselEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   149 RLEEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWtrscKELEQREAVWRREEESFNTYFSSEHSRLLRLW 228
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQLELQIASLNNEIERLEARLERLEDRRERLQ 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   229 RQVMGLRRQASEVKMgterdllqlggelvrtsRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKD 308
Cdd:TIGR02168  421 QEIEELLKKLEEAEL-----------------KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   309 LAQLQVQSDLDKaDLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLdtedGEGLQQTLRDLAQAA 388
Cdd:TIGR02168  484 LAQLQARLDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAAL----GGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   389 LSDTESGVQLSSSERTAdtsdGSLRGFSGQRTPTPPRHSPGRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGR 468
Cdd:TIGR02168  559 KKAIAFLKQNELGRVTF----LPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   469 YEASQELLGSVRKQLSDSEGERRGleeqlqrlrdqtaaSAQAQEDAQREAQRLRSANELLsrekgNLTHSLQVTQQQAKE 548
Cdd:TIGR02168  635 LELAKKLRPGYRIVTLDGDLVRPG--------------GVITGGSAKTNSSILERRREIE-----ELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   549 LRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQT 628
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   629 EKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLskmSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATt 708
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL---TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS- 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   709 mavEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLaqlsRQLSGRDQELEQALRESQrqv 788
Cdd:TIGR02168  852 ---EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL----RELESKRSELRRELEELR--- 921

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102   789 EALERAAREKEAMAKERAGLAVKLAAaerEGRTLSEEAIRLRLEKEALESSLfdvQRQLAQLEARREQL 857
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSE---EYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 451-1208 2.44e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.51  E-value: 2.44e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  451 IHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEG--ERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELl 528
Cdd:PTZ00121 1055 NHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEAteEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA- 1133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  529 srekgnlthslqvtqQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEqleVKRSGLTKE 608
Cdd:PTZ00121 1134 ---------------RKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE---VRKAEELRK 1195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  609 LVEVREAlSCAILQRDVLQTEKAEVAEALTKAEAGRaqlelsltklRAEEASLRDSlskmsalnESLAQDKLELNRLIAQ 688
Cdd:PTZ00121 1196 AEDARKA-EAARKAEEERKAEEARKAEDAKKAEAVK----------KAEEAKKDAE--------EAKKAEEERNNEEIRK 1256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  689 LEEEKVALLGRQQQAEHAttmavEKQELLEQLRLEQEVERqglqgslcvAEQAREALEQQilvlRSERSHLQEQLAQLSR 768
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKA-----EEARKADELKKAEEKKK---------ADEAKKAEEKK----KADEAKKKAEEAKKAD 1318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  769 QLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGlavKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQR-QL 847
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD---EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKaDE 1395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  848 AQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEE--KAALDKELMTQKLVQAEREAQASLREQRAaheEDLQRL 925
Cdd:PTZ00121 1396 AKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKAEEAKKKA---EEAKKA 1472

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  926 QHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAEsEKQQALSLKESEKTALSEKL 1005
Cdd:PTZ00121 1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEEKKKADEL 1551

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1006 MGTRHSLAAisleMERQKRDAQSRQEQDRNTLNALTSELRDL---------------------RAQLEEATAAHAQTVKE 1064
Cdd:PTZ00121 1552 KKAEELKKA----EEKKKAEEAKKAEEDKNMALRKAEEAKKAeearieevmklyeeekkmkaeEAKKAEEAKIKAEELKK 1627

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1065 LEE---RTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREA 1141
Cdd:PTZ00121 1628 AEEekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1142 LRRSNEELRSA--VKKAESER-ISLKLANEDKEQKLALLEEARVSvAKEAGELRASLQEVERSRLEARRE 1208
Cdd:PTZ00121 1708 KKKEAEEKKKAeeLKKAEEENkIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKE 1776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 759-1613 8.28e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 8.28e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   759 LQEQLAQLSRQLSGRDqeLEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALES 838
Cdd:TIGR02168  218 LKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   839 SLFDVQRQLAQLEARREQLEADSQALLLAKETLtgelagLRQQVTSTEEKAALDKELmtqKLVQAEREAQASLREQRAAH 918
Cdd:TIGR02168  296 EISRLEQQKQILRERLANLERQLEELEAQLEEL------ESKLDELAEELAELEEKL---EELKEELESLEAELEELEAE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   919 EEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELlARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEK 998
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   999 TALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSE---LRDLRAQLEEATAAHAQTVKELEERTGNLGR- 1074
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARldsLERLQENLEGFSEGVKALLKNQSGLSGILGVl 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1075 --------QREACMREAEELRTQLRV-------------LEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLS 1133
Cdd:TIGR02168  526 selisvdeGYEAAIEAALGGRLQAVVvenlnaakkaiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAK 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1134 EGAKEREALRRSNEELRSAVKKAESERISLKLANEdkeqklallEEARVSVAKEAGELRASLQEVERSRLEARRELQELR 1213
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK---------LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1214 RqmktldsdngrlgrELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEfrarergl 1293
Cdd:TIGR02168  677 R--------------EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD-------- 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1294 lgsLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRrglgl 1373
Cdd:TIGR02168  735 ---LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD----- 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1374 grvssspareapaggsgdglsspspleysprsqppspgliaspappdldpeAVRDALRDFLQELRSAQRERDELKVQTST 1453
Cdd:TIGR02168  807 ---------------------------------------------------ELRAELTLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1454 LSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATES 1533
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRR 915

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1534 ELRASQEKVSKMKATEAKLESDKRRLKEVLdasesrsikLELQRRALEGELQRSRlglgDREAHAQALQDRVDSLQRQVA 1613
Cdd:TIGR02168  916 ELEELREKLAQLELRLEGLEVRIDNLQERL---------SEEYSLTLEEAEALEN----KIEDDEEEARRRLKRLENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 906-1373 3.31e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.46  E-value: 3.31e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  906 EAQASLREQRAAHEEDLQRLQHE-KEAAWRELQAERAQLQGQLQqEREELLARMEAEKEELSKEIAALQQERDEglllaE 984
Cdd:COG1196   206 ERQAEKAERYRELKEELKELEAElLLLKLRELEAELEELEAELE-ELEAELEELEAELAELEAELEELRLELEE-----L 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  985 SEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHA---QT 1061
Cdd:COG1196   280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEeaeAE 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1062 VKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREA 1141
Cdd:COG1196   360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1142 LRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVErsRLEARRELQELRRQMKTLDS 1221
Cdd:COG1196   440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL--EAEADYEGFLEGVKAALLLA 517

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1222 DNGRLGRELADLQGRLALGERT--EKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQ--EQEAEFRARERGLLGSL 1297
Cdd:COG1196   518 GLRGLAGAVAVLIGVEAAYEAAleAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPldKIRARAALAAALARGAI 597

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102 1298 EEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGL 1373
Cdd:COG1196   598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA 673
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 952-1806 3.59e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 88.59  E-value: 3.59e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   952 EELLARMEAEKEELSKEIAALQQERDEglllaeSEKQQALS--LKESEKTALSEKLMGTRHSLAAISLEM---ERQKRDA 1026
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREK------AERYQALLkeKREYEGYELLKEKEALERQKEAIERQLaslEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1027 QSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVK----ELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRR 1102
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKekigELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1103 EL------LEAQRKGRDS-QDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLA 1175
Cdd:TIGR02169  337 EIeelereIEEERKRRDKlTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1176 LLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREAlglr 1255
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL---- 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1256 qrllkgeSSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRL--------------------LDSARSLE 1315
Cdd:TIGR02169  493 -------AEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYataievaagnrlnnvvveddAVAKEAIE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1316 ------------LRLEAVRAETSELGLrlsAAEGRAQGLEVELARVEAQRRVAEAQLGG-------LRSALRRGLGLGRV 1376
Cdd:TIGR02169  566 llkrrkagratfLPLNKMRDERRDLSI---LSEDGVIGFAVDLVEFDPKYEPAFKYVFGdtlvvedIEAARRLMGKYRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1377 SSSPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGLIASpappdlDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQ 1456
Cdd:TIGR02169  643 TLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE------RLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1457 QLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLqateselr 1536
Cdd:TIGR02169  717 KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL-------- 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1537 aSQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQrsrlglgDREAHAQALQDRVDSLQRQVADSE 1616
Cdd:TIGR02169  789 -SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ-------ELQEQRIDLKEQIKSIEKEIENLN 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1617 VKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLtdaltqssaslsstqdknlhlqkalstcEHDRQVLQERLDAARQAL 1696
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESRLGDLKKERDEL----------------------------EAQLRELERKIEELEAQI 912

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1697 SEARRQSSSLGEQVQTLRGELASLELQRGD-----AEGQLQQLQQALRQRQEGEAMALRSVQKLQ-EERRLLQERLGSLQ 1770
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipEEELSLEDVQAELQRVEEEIRALEPVNMLAiQEYEEVLKRLDELK 992

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 568931102  1771 RALAQLEAEKRDLERSALQFD-KDRVALRKTLDKVER 1806
Cdd:TIGR02169  993 EKRAKLEEERKAILERIEEYEkKKREVFMEAFEAINE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1106-1915 1.04e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.03  E-value: 1.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1106 EAQRKGRDSQDSSEAHRQEASELRR---SLSEGAKEREALRRSNEELRSAvkkaesERISLKLANEDKEQKLALLEEARV 1182
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERqlkSLERQAEKAERYKELKAELREL------ELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1183 SVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGE 1262
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1263 SSLEALKQELQGSQRKLQEQEAEFRArergLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGL 1342
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELES----LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1343 EVELARVEAQRRVAEAQLGGLRSALrrglglgrvsSSPAREAPAGGSGDglsspspleysprsqppspgLIASPAPPDLD 1422
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKL----------EEAELKELQAELEE--------------------LEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1423 PEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDhaasRAKQLQKAVAEsEEAWRSADRRLSGAQAELAL 1502
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----NLEGFSEGVKA-LLKNQSGLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1503 QEESVRRSKRE-CRATLDqmAVLERSLQATESELrASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQ----- 1576
Cdd:TIGR02168  531 VDEGYEAAIEAaLGGRLQ--AVVVENLNAAKKAI-AFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGvakdl 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1577 -------RRALEGELQRSRLGlgDREAHAQALQDRVDSLQRQVadseVKAGTLQLTVERLSGALAKVEESEGNLRSKVQS 1649
Cdd:TIGR02168  608 vkfdpklRKALSYLLGGVLVV--DDLDNALELAKKLRPGYRIV----TLDGDLVRPGGVITGGSAKTNSSILERRREIEE 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1650 LTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEG 1729
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1730 QLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKL 1809
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1810 RSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHnpvqpEAGEQQLELQQEVERLRSAQVQTERT 1889
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA-----LLRSELEELSEELRELESKRSELRRE 916

                          810       820
                   ....*....|....*....|....*....
gi 568931102  1890 LEA---RERAHRQRVSGLEEQVSTLKAQL 1915
Cdd:TIGR02168  917 LEElreKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 582-1329 7.15e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.96  E-value: 7.15e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   582 ARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVL-QTEKAEVAEALTKAEAGRAQLElsltKLRAEEAS 660
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLkEKREYEGYELLKEKEALERQKE----AIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   661 LRDSLSKMSALNESLAQDKLELNRLIAQLEEeKVALLGRQQQAEHATTMAvekqelleqlrlEQEVERQGLQGSLCVAEQ 740
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNK-KIKDLGEEEQLRVKEKIG------------ELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   741 AREALEQQILVLRSERSHLQEQLAQLSR----------QLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAglaV 810
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEReieeerkrrdKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR---E 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   811 KLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEK-- 888
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEly 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   889 ------AALDKEL--MTQKLVQAEREAQASLREQR--AAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARM 958
Cdd:TIGR02169  473 dlkeeyDRVEKELskLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   959 EAEKEELSKEIAAL------------------QQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEME 1020
Cdd:TIGR02169  553 VVEDDAVAKEAIELlkrrkagratflplnkmrDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAA 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1021 RQKRDAQSRQEQDRNTLN---ALTSELRDLRAQLEEATAAHAQtVKELEERTGNLGRQREACMREAEELRTQLRVLEDTR 1097
Cdd:TIGR02169  633 RRLMGKYRMVTLEGELFEksgAMTGGSRAPRGGILFSRSEPAE-LQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1098 DGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLAL- 1176
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHs 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1177 -----------LEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEK 1245
Cdd:TIGR02169  792 ripeiqaelskLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1246 ESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEfRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAET 1325
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ-IEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950


                   ....
gi 568931102  1326 SELG 1329
Cdd:TIGR02169  951 LSLE 954
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1018-1808 1.02e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.58  E-value: 1.02e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1018 EMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTR 1097
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1098 DGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSE-GAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLAL 1176
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1177 LEEARVSVAKEAGELRASLQEVERSR-------LEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRR 1249
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRdklteeyAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1250 EALGLRQRLLKGESSLEALKQELQGsqrkLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELG 1329
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAG----IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1330 LRLSAaegraqgLEVELARVEAQRRVAEAQLGGLRSA---LRRGLG--------LGRVSS--SPAREAPAGGS------G 1390
Cdd:TIGR02169  483 KELSK-------LQRELAEAEAQARASEERVRGGRAVeevLKASIQgvhgtvaqLGSVGEryATAIEVAAGNRlnnvvvE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1391 DGLSSPSPLEYSPRSQ--------------PPSPGLIASPAPP--------DLDPE---AVRDALRDFL--QELRSAQRE 1443
Cdd:TIGR02169  556 DDAVAKEAIELLKRRKagratflplnkmrdERRDLSILSEDGVigfavdlvEFDPKyepAFKYVFGDTLvvEDIEAARRL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1444 RDelKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAV 1523
Cdd:TIGR02169  636 MG--KYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1524 LERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAH------ 1597
Cdd:TIGR02169  714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsri 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1598 ------AQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHL 1671
Cdd:TIGR02169  794 peiqaeLSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEL 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1672 QKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEgEAMALRS 1751
Cdd:TIGR02169  874 EAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE-IPEEELS 952

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568931102  1752 VQKLQEERRLLQERLGSLQ----RALAQLEAEKR---DLERSALQFDKDRVALRKTLDKVEREK 1808
Cdd:TIGR02169  953 LEDVQAELQRVEEEIRALEpvnmLAIQEYEEVLKrldELKEKRAKLEEERKAILERIEEYEKKK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 15-609 1.18e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 1.18e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   15 QQELSRVEDLLAQSRAERDEL------AIKYNAVNERLEQAvrletgeleaqeprgLVRQSVELRRQLQEEQSSYRRKLQ 88
Cdd:COG1196   185 EENLERLEDILGELERQLEPLerqaekAERYRELKEELKEL---------------EAELLLLKLRELEAELEELEAELE 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   89 AYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEEEQQRSASLAQVNAMLR 168
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  169 EQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESfntyFSSEHSRLLRLWRQVMGLRRQASEVKMGTERD 248
Cdd:COG1196   330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE----LAEAEEELEELAEELLEALRAAAELAAQLEEL 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  249 LLQLGGELVRTSRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVT 328
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  329 ELALSVEHLQNQNSEKDQ----------VNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQL 398
Cdd:COG1196   486 LAEAAARLLLLLEAEADYegflegvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  399 SSSERTADTSDGSLRGFSGQRTPTPPRHSPGRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGS 478
Cdd:COG1196   566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  479 VRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQA 558
Cdd:COG1196   646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568931102  559 AQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKEL 609
Cdd:COG1196   726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1189-1851 1.38e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.06  E-value: 1.38e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1189 GELRASLQEVERSRLEARReLQELRRQMKTLDSDngRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEAL 1268
Cdd:COG1196   196 GELERQLEPLERQAEKAER-YRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1269 KQELQgsqrKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELAR 1348
Cdd:COG1196   273 RLELE----ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1349 VEAQRRVAEAQLgglrsalrrglglgrvssspareapaggsgdglsspspleysprsqppspgliaspappdldpEAVRD 1428
Cdd:COG1196   349 AEEELEEAEAEL---------------------------------------------------------------AEAEE 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1429 ALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVR 1508
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1509 RSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASE--SRSIKLELQRRALEGELQR 1586
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgfLEGVKAALLLAGLRGLAGA 525

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1587 SRLGLGDREAHAQALQDRVdslqrqvadsevkAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQD 1666
Cdd:COG1196   526 VAVLIGVEAAYEAALEAAL-------------AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAL 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1667 KNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEA 1746
Cdd:COG1196   593 ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1747 MALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLD 1826
Cdd:COG1196   673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                         650       660
                  ....*....|....*....|....*
gi 568931102 1827 RTLTGAELDLAEAQQQIQHLEAQVD 1851
Cdd:COG1196   753 LEELPEPPDLEELERELERLEREIE 777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1436-1921 1.09e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1436 ELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECR 1515
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1516 ATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDRE 1595
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1596 AHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKAL 1675
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1676 STCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELAS-------LELQRGDAEGQLQQLQQALRQRQEGEAMA 1748
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalllAGLRGLAGAVAVLIGVEAAYEAALEAALA 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1749 LRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRT 1828
Cdd:COG1196   546 AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1829 LTGAELDLAEAQQQIQHLEAQVDVALEGNH-NPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQ 1907
Cdd:COG1196   626 TLVAARLEAALRRAVTLAGRLREVTLEGEGgSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                         490
                  ....*....|....
gi 568931102 1908 VSTLKAQLHQELRR 1921
Cdd:COG1196   706 ERELAEAEEERLEE 719
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 686-1367 1.43e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.73  E-value: 1.43e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   686 IAQLEEEKVALLGR----QQQAEHATTMAVEKQELLEQLRLEQE--VERQGLQGSLCVAEQ-----AREALEQQILVLRS 754
Cdd:TIGR02169  165 VAEFDRKKEKALEEleevEENIERLDLIIDEKRQQLERLRREREkaERYQALLKEKREYEGyellkEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   755 ERSHLQEQLAQLSRQLSGRDQELEQA---LRESQRQVEAL--ERAAREKEAMAK---ERAGLAVKLAAAEREGRTLSEEA 826
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIeqlLEELNKKIKDLgeEEQLRVKEKIGEleaEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   827 IRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGL--------RQQVTSTEEKAALDKEL--- 895
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefaetrDELKDYREKLEKLKREInel 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   896 -----MTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQA---ERAQLQGQLQQEREELLARmEAEKEELSK 967
Cdd:TIGR02169  405 kreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKqewKLEQLAADLSKYEQELYDL-KEEYDRVEK 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   968 EIAALQQErdegllLAESEKQQALSLKESEKTALSEKLMGTR----HSLAAISLEMERQ--------------------K 1023
Cdd:TIGR02169  484 ELSKLQRE------LAEAEAQARASEERVRGGRAVEEVLKASiqgvHGTVAQLGSVGERyataievaagnrlnnvvvedD 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1024 RDAQS------RQEQDRNT---LNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLE 1094
Cdd:TIGR02169  558 AVAKEaiellkRRKAGRATflpLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMG 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1095 DTR-DGLRRELLE-------AQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLA 1166
Cdd:TIGR02169  638 KYRmVTLEGELFEksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1167 NEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLA-------- 1238
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLShsripeiq 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1239 -LGERTEKESRREALGLR------QRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSA 1311
Cdd:TIGR02169  798 aELSKLEEEVSRIEARLReieqklNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102  1312 RSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSAL 1367
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 470-1237 2.43e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.96  E-value: 2.43e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   470 EASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAaSAQAQEDAQREAQRLRSAneLLSREKGNLTHSLQVTQQQAKEL 549
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRERE-KAERYQALLKEKREYEGY--ELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   550 RQELEKLQAAQEELKRQHNQLEDAQED--------SVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAIL 621
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEElnkkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   622 QRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALN--------------ESLAQDKLELNRLIA 687
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdelkdyreklEKLKREINELKRELD 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   688 QLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLS 767
Cdd:TIGR02169  410 RLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   768 RQLS---GRDQELEQALRESQRQVEALERAAR------EKEAMAKERAGLAVKLAAAER------EGRTLSEEAIRLRLE 832
Cdd:TIGR02169  490 RELAeaeAQARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERYATAIEVAAGNRlnnvvvEDDAVAKEAIELLKR 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   833 KEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQV---TSTEEKAALDKELMTQ-KLVQAERE-- 906
Cdd:TIGR02169  570 RKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVfgdTLVVEDIEAARRLMGKyRMVTLEGElf 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   907 -----------AQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQgQLQQEREELLARMEAEK---EELSKEIAAL 972
Cdd:TIGR02169  650 eksgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR-RIENRLDELSQELSDASrkiGEIEKEIEQL 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   973 QQ------ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMER-QKRDAQSRQEQDRNTLNALTSELR 1045
Cdd:TIGR02169  729 EQeeeklkERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVS 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1046 DLRAQLEEataahaqtvkeLEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEA 1125
Cdd:TIGR02169  809 RIEARLRE-----------IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1126 SELRRSLSEGAKEREALRRSNEELRSAVKKAESERislklanEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEA 1205
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEAQLRELERKIEELEAQI-------EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 568931102  1206 ------RRELQELRRQMKTLDSDNGRLGRELADLQGRL 1237
Cdd:TIGR02169  951 lsledvQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL 988
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
776-1282 1.02e-13

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 76.88  E-value: 1.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  776 ELEQALRESQRQVEALERAAREKEAMAKERAGLAVklAAAEREGRTLSEEAIRLRLEKEALEsslfDVQRQLAQLEARRE 855
Cdd:COG4913   239 RAHEALEDAREQIELLEPIRELAERYAAARERLAE--LEYLRAALRLWFAQRRLELLEAELE----ELRAELARLEAELE 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  856 QLEAdsqalllAKETLTGELAGLRQQVTS--TEEKAALDKEL--MTQKLVQAEREAQ------ASLREQRAAHEEDLQRL 925
Cdd:COG4913   313 RLEA-------RLDALREELDELEAQIRGngGDRLEQLEREIerLERELEERERRRArleallAALGLPLPASAEEFAAL 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  926 QHEKEAAWRELQAERAQLQgQLQQEREELLARMEAEKEELSKEIAALQQER---DEGLLLAESEKQQALSLKESE----- 997
Cdd:COG4913   386 RAEAAALLEALEEELEALE-EALAEAEAALRDLRRELRELEAEIASLERRKsniPARLLALRDALAEALGLDEAElpfvg 464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  998 ------------KTALsEKLMGTRhslaAISLEMERQKRDAQSR---QEQDRNTLN---ALTSELRDLRAQLEEATAAHA 1059
Cdd:COG4913   465 elievrpeeerwRGAI-ERVLGGF----ALTLLVPPEHYAAALRwvnRLHLRGRLVyerVRTGLPDPERPRLDPDSLAGK 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1060 QTVKE------LEERTGNlgRQREACMREAEELRTQLRVLedTRDGLRRELLEAQRK------------GRDSQDSSEAH 1121
Cdd:COG4913   540 LDFKPhpfrawLEAELGR--RFDYVCVDSPEELRRHPRAI--TRAGQVKGNGTRHEKddrrrirsryvlGFDNRAKLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1122 RQEASELRRSLSEGAKEREALRRSNEELR------SAVKKAESERISLKLANE---DKEQKLALLEEARVSVAkeagELR 1192
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALQerrealQRLAEYSWDEIDVASAEReiaELEAELERLDASSDDLA----ALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1193 ASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQEL 1272
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENL 771

                         570
                  ....*....|
gi 568931102 1273 QGSQRKLQEQ 1282
Cdd:COG4913   772 EERIDALRAR 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 7-805 1.78e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 1.78e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102     7 LQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAV-RLETGELEAQEPRGLVRQSVELRRQLQEEQSSYRR 85
Cdd:TIGR02168  286 LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELEsKLDELAEELAELEEKLEELKEELESLEAELEELEA 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    86 KLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEEEQQR--SASLAQV 163
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelQAELEEL 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   164 NAMLREQLDQANLANQALsedirkvtsdwtrscKELEQREAVWRREEESFNTYFSSEHSR---LLRLWRQVMGLRRQASE 240
Cdd:TIGR02168  446 EEELEELQEELERLEEAL---------------EELREELEEAEQALDAAERELAQLQARldsLERLQENLEGFSEGVKA 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   241 VKMgterdllqlggelvrtSRAVQELGLGLSASLHRAESKAEAALEkqkllqAQLEEQLQAKLLREKDLAQLQVQSDLDK 320
Cdd:TIGR02168  511 LLK----------------NQSGLSGILGVLSELISVDEGYEAAIE------AALGGRLQAVVVENLNAAKKAIAFLKQN 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   321 AdlSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRlqeqttldtedgeglqqTLRDLAQAALSDTESGVQLSS 400
Cdd:TIGR02168  569 E--LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV-----------------KFDPKLRKALSYLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   401 SERTADTSDGSLRGfsGQRTPTPPRHSPGRGRSPRRGLSPAcsDSSTLTLiHSALHKRQLQVQDMRGRYEASQELLGSVR 480
Cdd:TIGR02168  630 DLDNALELAKKLRP--GYRIVTLDGDLVRPGGVITGGSAKT--NSSILER-RREIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   481 KQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQ 560
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   561 EELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKA 640
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   641 EAGRAQLELSLTKL-------RAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEhattmaVEK 713
Cdd:TIGR02168  865 EELIEELESELEALlneraslEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE------VRI 938

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   714 QELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQE-QLAQLS--RQLSGRDQELEQALRESQRQVEA 790
Cdd:TIGR02168  939 DNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvNLAAIEeyEELKERYDFLTAQKEDLTEAKET 1018

                          810
                   ....*....|....*
gi 568931102   791 LERAAREKEAMAKER 805
Cdd:TIGR02168 1019 LEEAIEEIDREARER 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-721 3.05e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 3.05e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102     2 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAVRlETGELEAQeprglVRQSVELRRQLQEEQS 81
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN-EISRLEQQ-----KQILRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    82 SYRRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEEEQQRSASLA 161
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   162 QVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEEsfnTYFSSEHSRLLRLWRQVMGLRRQASEV 241
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL---EELQEELERLEEALEELREELEEAEQA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   242 KMGTERDLLQLGGELVRTSRAVQEL-------------------GLGLSASLHRAESKAEAALEkqkllqAQLEEQLQAK 302
Cdd:TIGR02168  477 LDAAERELAQLQARLDSLERLQENLegfsegvkallknqsglsgILGVLSELISVDEGYEAAIE------AALGGRLQAV 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   303 LLREKDLAQLQVQSDLDKAdlSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRlqeqttldtedgeglqqTLR 382
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNE--LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV-----------------KFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   383 DLAQAALSDTESGVQLSSSERTADTSDGSLRGFSGQRTPTPPRHSPG---RGRSPRRGLSPACSDS------STLTLIHS 453
Cdd:TIGR02168  612 PKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGgviTGGSAKTNSSILERRReieeleEKIEELEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   454 ALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRL------------ 521
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELeaeieeleerle 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   522 --RSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLE 599
Cdd:TIGR02168  772 eaEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   600 VKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLElslTKLRAEEASLRDSLSKMSALNESLAQDK 679
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS---EELRELESKRSELRRELEELREKLAQLE 928

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 568931102   680 LELNRLIAQLEEEKVALLGRQQ-QAEHATTMAVEKQELLEQLR 721
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEAR 971
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1435-1911 5.65e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 5.65e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1435 QELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKREC 1514
Cdd:COG1196   309 ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1515 RATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDR 1594
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1595 EAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGN-LRSKVQSLTDALTQSSASLSSTQDKNLHLQK 1673
Cdd:COG1196   469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLaGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1674 ALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQ 1753
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1754 KLQEE-----RRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRT 1828
Cdd:COG1196   629 AARLEaalrrAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1829 LTGAELDLAEAQQQIQHLEAQVDVALEgnhnpvqpeageQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQV 1908
Cdd:COG1196   709 LAEAEEERLEEELEEEALEEQLEAERE------------ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                  ...
gi 568931102 1909 STL 1911
Cdd:COG1196   777 EAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 658-1305 3.09e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.48  E-value: 3.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  658 EASLRDSLSKMSALNESLAQ---DKLELNRLIAQLEEEKvallGRQQQAEHATTMAVEKQELLEQLRLEQEVERQglqgs 734
Cdd:PTZ00121 1059 KAEAKAHVGQDEGLKPSYKDfdfDAKEDNRADEATEEAF----GKAEEAKKTETGKAEEARKAEEAKKKAEDARK----- 1129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  735 lcvAEQAREAleQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAA 814
Cdd:PTZ00121 1130 ---AEEARKA--EDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEA 1204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  815 AER-EGRTLSEEAIRLRLEKEALESSLFDVQRQLAQlEARREQLEADSQALLLAKETLTGELAGlRQQVTSTEEKAALDK 893
Cdd:PTZ00121 1205 ARKaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE-EAKKAEEERNNEEIRKFEEARMAHFAR-RQAAIKAEEARKADE 1282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  894 ElmtqklvqaeREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARmEAEKEELSKEIAALQ 973
Cdd:PTZ00121 1283 L----------KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK-KAEEAKKAAEAAKAE 1351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  974 QERDEGLLLAESEKQQALSLKESEKTALSEKLMGtrhslaaiSLEMERQKRDAQSRQEQDRNtlnaltsELRDLRAQLEE 1053
Cdd:PTZ00121 1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK--------KAEEKKKADEAKKKAEEDKK-------KADELKKAAAA 1416

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1054 ATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRREllEAQRKGRDSQDSSEAHRQeASELRRSLS 1133
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKA--EEAKKADEAKKKAEEAKK-ADEAKKKAE 1493

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1134 EGAKEREALRRSNEELRSA--VKKAESERislklanedKEQKLALLEEARvsvakEAGELRaslQEVERSRLEARRELQE 1211
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKAdeAKKAEEAK---------KADEAKKAEEAK-----KADEAK---KAEEKKKADELKKAEE 1556

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1212 LRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALK-QELQGSQRKLQEQEAEFRARE 1290
Cdd:PTZ00121 1557 LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKaEEAKIKAEELKKAEEEKKKVE 1636

                         650
                  ....*....|....*
gi 568931102 1291 RGLLGSLEEARGAEK 1305
Cdd:PTZ00121 1637 QLKKKEAEEKKKAEE 1651
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 926-1638 3.35e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 3.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   926 QHEKEAAWRELQAERAQLQGQLQQEREELlARMEAEKEELSKEIAALQQERDEglllaESEKQQALSLKES-EKTALSEK 1004
Cdd:TIGR02169  225 GYELLKEKEALERQKEAIERQLASLEEEL-EKLTEEISELEKRLEEIEQLLEE-----LNKKIKDLGEEEQlRVKEKIGE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1005 LMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQ---TVKELEERTGNLGRQREACMR 1081
Cdd:TIGR02169  299 LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKlteEYAELKEELEDLRAELEEVDK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1082 EAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERI 1161
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1162 SLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQG------ 1235
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSvgerya 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1236 ---RLALGER--------------------TEKESRREALGLRqRLLKGESSLEALKQE-LQGSQRKLQEQEAEFRA--- 1288
Cdd:TIGR02169  539 taiEVAAGNRlnnvvveddavakeaiellkRRKAGRATFLPLN-KMRDERRDLSILSEDgVIGFAVDLVEFDPKYEPafk 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1289 ---RERGLLGSLEEARgaekRLLDSARSLELRLEAVRAETSELG--LRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGL 1363
Cdd:TIGR02169  618 yvfGDTLVVEDIEAAR----RLMGKYRMVTLEGELFEKSGAMTGgsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSL 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1364 RSALRRGLGLGRVSSSPAREApaggsgdglsSPSPLEYSPRSQPPspgliaspappDLDPEAVRDALRDFLQELRSAQRE 1443
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDA----------SRKIGEIEKEIEQL-----------EQEEEKLKERLEELEEDLSSLEQE 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1444 RDELKVQTSTLSQQLVEMEA------------ERDHAASRAKQLQ-------KAVAESEEAWRSADRRLSGAQAELALQE 1504
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEdlhkleealndlEARLSHSRIPEIQaelskleEEVSRIEARLREIEQKLNRLTLEKEYLE 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1505 ESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGEL 1584
Cdd:TIGR02169  833 KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQI 912

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1585 QRSRLGLGDREAHAQALQDRVDSLQRQVAD------SEVKAGTLQLTVERLSGALAKVEE 1638
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeEELSLEDVQAELQRVEEEIRALEP 972
PTZ00121 PTZ00121
MAEBL; Provisional
 753-1357 4.15e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.10  E-value: 4.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  753 RSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAERegrtlSEEAIRLRLE 832
Cdd:PTZ00121 1071 GLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARK-----AEDARKAEEA 1145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  833 KEALESSLFDVQRQLAqlEARREQLEADsqalllAKETLTGELAGLRQQVTSTEE--KAALDKELMTQKLVQAEREAQAS 910
Cdd:PTZ00121 1146 RKAEDAKRVEIARKAE--DARKAEEARK------AEDAKKAEAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEA 1217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  911 LREQRAAHEEDLQRLQhekEAAWRELQAERAQLQGQLQQEREELLARMeAEKEELSKEIAALQQERDEGLLLAEsEKQQA 990
Cdd:PTZ00121 1218 RKAEDAKKAEAVKKAE---EAKKDAEEAKKAEEERNNEEIRKFEEARM-AHFARRQAAIKAEEARKADELKKAE-EKKKA 1292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  991 LSLKESEKTALSEKLMGtrhslaaiSLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELE---E 1067
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKK--------KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEaaeE 1364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1068 RTGNLGRQREACMREAEELRTQLRVLEDTRDGLRREllEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNE 1147
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA--EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1148 ELRS--AVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGR 1225
Cdd:PTZ00121 1443 AKKAdeAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAK 1522

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1226 LGRELADLQGRLALGERTEKESRREALGLRQrllkgESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEK 1305
Cdd:PTZ00121 1523 KADEAKKAEEAKKADEAKKAEEKKKADELKK-----AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568931102 1306 RLLDSARSLELRLEAVRAETSEL-GLRLSAAEGRAQGLEVELARVEAQRRVAE 1357
Cdd:PTZ00121 1598 MKLYEEEKKMKAEEAKKAEEAKIkAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1544-1906 4.31e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 4.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1544 KMKATEAKLEsdkrRLKEVLDASESRSIKLELQRRALE--GELQRSRlglgdREAHAQALQDRVDSLQRQVADSEVKAGT 1621
Cdd:COG1196   180 KLEATEENLE----RLEDILGELERQLEPLERQAEKAEryRELKEEL-----KELEAELLLLKLRELEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1622 LQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARR 1701
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1702 QSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKR 1781
Cdd:COG1196   331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1782 DLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEgnhnpv 1861
Cdd:COG1196   411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE------ 484

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 568931102 1862 QPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEE 1906
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 519-1157 1.05e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.53  E-value: 1.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   519 QRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEklqaAQEELKRQHNQLEDAQEDSVQ------EGARARRE--LER 590
Cdd:pfam15921   92 RRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERD----AMADIRRRESQSQEDLRNQLQntvhelEAAKCLKEdmLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   591 SHRQLEQLE---VKRSGLTKE----LVEVREALSCAILQRDVLQT-EKAEVAEALTKAeagRAQLELSLTKLRAEEASLR 662
Cdd:pfam15921  168 SNTQIEQLRkmmLSHEGVLQEirsiLVDFEEASGKKIYEHDSMSTmHFRSLGSAISKI---LRELDTEISYLKGRIFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   663 DSLSKMsalnESLAQDKLEL------NRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLR--------------- 721
Cdd:pfam15921  245 DQLEAL----KSESQNKIELllqqhqDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQeqarnqnsmymrqls 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   722 -LEQEVE--RQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREK 798
Cdd:pfam15921  321 dLESTVSqlRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQN 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   799 EAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALES------------------SLFDVQRQLAQLEARREQLEAD 860
Cdd:pfam15921  401 KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgqmerqmaaiqgkneSLEKVSSLTAQLESTKEMLRKV 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   861 SQALLLAKETLTGELAGLRQQVTSTEEK---------------AALDKELMTQKLVQAE----REAQA---SLREQRAAH 918
Cdd:pfam15921  481 VEELTAKKMTLESSERTVSDLTASLQEKeraieatnaeitklrSRVDLKLQELQHLKNEgdhlRNVQTeceALKLQMAEK 560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   919 EEDLQRLQHEKEAAWR----------ELQAERAQLQGQLQQEREELLA------RMEAEKEELSKEIAALQQERDEgLLL 982
Cdd:pfam15921  561 DKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEKEINDRRLELQEfkilkdKKDAKIRELEARVSDLELEKVK-LVN 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   983 AESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATaahaQTV 1062
Cdd:pfam15921  640 AGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR----NTL 715

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1063 KELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREAL 1142
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVL 795

                          730
                   ....*....|....*
gi 568931102  1143 RRSNEELRSAVKKAE 1157
Cdd:pfam15921  796 RSQERRLKEKVANME 810
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1424-1935 1.07e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 1.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1424 EAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQ 1503
Cdd:COG1196   263 AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1504 EESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLkevldasESRSIKLELQRRALEGE 1583
Cdd:COG1196   343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL-------AAQLEELEEAEEALLER 415

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1584 LQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSS 1663
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1664 tqDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQE 1743
Cdd:COG1196   496 --LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1744 GEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDlERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERG 1823
Cdd:COG1196   574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1824 RLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSG 1903
Cdd:COG1196   653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                         490       500       510
                  ....*....|....*....|....*....|..
gi 568931102 1904 LEEQVSTLKAQLHQELRRSSASVSLPPGTPEK 1935
Cdd:COG1196   733 EREELLEELLEEEELLEEEALEELPEPPDLEE 764
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
495-1050 3.11e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 68.79  E-value: 3.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  495 EQLQRLRDQTAASAQAQEDAQR--------EAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQ 566
Cdd:COG4913   252 ELLEPIRELAERYAAARERLAEleylraalRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  567 HNQ--------LEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALScaiLQRDVLQTEKAEVAEALT 638
Cdd:COG4913   332 IRGnggdrleqLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAA---ALLEALEEELEALEEALA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  639 KAEAGRAQLELSLTKLRAEEASLRDSLSKM--------SALNESLAQDKLELnRLIAQL----EEEKV------ALLGRQ 700
Cdd:COG4913   409 EAEAALRDLRRELRELEAEIASLERRKSNIparllalrDALAEALGLDEAEL-PFVGELievrPEEERwrgaieRVLGGF 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  701 qqaehATTMAVEKQELLEQLRLeqeVERQGLQGSLcVAEQAREALEQQILVLRSERShlqeqlaqLSRQLSGRDQELEQA 780
Cdd:COG4913   488 -----ALTLLVPPEHYAAALRW---VNRLHLRGRL-VYERVRTGLPDPERPRLDPDS--------LAGKLDFKPHPFRAW 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  781 LRESQRQVEALERAAREKEAmakERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESslFDVQRQLAQLEARREQLEAD 860
Cdd:COG4913   551 LEAELGRRFDYVCVDSPEEL---RRHPRAITRAGQVKGNGTRHEKDDRRRIRSRYVLG--FDNRAKLAALEAELAELEEE 625

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  861 SQALLLAKETLTGELAGLRQQVTSTEEKAALDkelmtqklvqAEREAQASLREQRAAHEEDLQRLQhEKEAAWRELQAER 940
Cdd:COG4913   626 LAEAEERLEALEAELDALQERREALQRLAEYS----------WDEIDVASAEREIAELEAELERLD-ASSDDLAALEEQL 694

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  941 AQLQGQLQQEREElLARMEAEKEELSKEIAALQQERDEglllAESEKQQALSLKESEKTALSEKlmgtRHSLAAISLEME 1020
Cdd:COG4913   695 EELEAELEELEEE-LDELKGEIGRLEKELEQAEEELDE----LQDRLEAAEDLARLELRALLEE----RFAAALGDAVER 765

                         570       580       590
                  ....*....|....*....|....*....|
gi 568931102 1021 RQKRDAQSRQEQDRNTLNALTSELRDLRAQ 1050
Cdd:COG4913   766 ELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 458-1239 3.20e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 3.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   458 RQLQVQDMRGRYEASQELLGSVRK----QLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQR-------EAQRLRSANE 526
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAekerELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKrrdklteEYAELKEELE 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   527 LLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLT 606
Cdd:TIGR02169  368 DLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   607 KELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLI 686
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTV 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   687 AQLEEEK--------VALLGRQQQAEHAT-TMAVEKQELLEQLRL--------------EQEVERQGLQGSLCVA----- 738
Cdd:TIGR02169  528 AQLGSVGeryataieVAAGNRLNNVVVEDdAVAKEAIELLKRRKAgratflplnkmrdeRRDLSILSEDGVIGFAvdlve 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   739 ----------------------EQAREALEQQILVLrsershLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAR 796
Cdd:TIGR02169  608 fdpkyepafkyvfgdtlvvediEAARRLMGKYRMVT------LEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE 681

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   797 EKEAMAKERAGLAVKLAAAERegrtlseeairlrlEKEALESSLFDVQRQLAQLEARREQLEADsqalllaKETLTGELA 876
Cdd:TIGR02169  682 RLEGLKRELSSLQSELRRIEN--------------RLDELSQELSDASRKIGEIEKEIEQLEQE-------EEKLKERLE 740

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   877 GLRQQVTSTEEKAAldkelmtqklvqAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLA 956
Cdd:TIGR02169  741 ELEEDLSSLEQEIE------------NVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVS 808

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   957 RMEAEKEELSKEIAALQQERDegllLAESEKQqalslkesektalseklmgtrhslaaislEMERQKRDAQSRQEQDRNT 1036
Cdd:TIGR02169  809 RIEARLREIEQKLNRLTLEKE----YLEKEIQ-----------------------------ELQEQRIDLKEQIKSIEKE 855

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1037 LNALTSELRDLRAQLEEATAAhaqtVKELEERTGNLGRQReacmreaEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQD 1116
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAA----LRDLESRLGDLKKER-------DELEAQLRELERKIEELEAQIEKKRKRLSELKA 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1117 SSEAHRQEASELRRSLSEGAKEREALrRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARvsvaKEAGELRASLQ 1196
Cdd:TIGR02169  925 KLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLE 999

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*...
gi 568931102  1197 EVERSRLEARRELQELRRQ--MKTLDSDN---GRLGRELADLQGRLAL 1239
Cdd:TIGR02169 1000 EERKAILERIEEYEKKKREvfMEAFEAINenfNEIFAELSGGTGELIL 1047
PTZ00121 PTZ00121
MAEBL; Provisional
 832-1587 3.35e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.01  E-value: 3.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  832 EKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEE--KAALDKELMTQKLVQAEREAQA 909
Cdd:PTZ00121 1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEarKAEDAKRVEIARKAEDARKAEE 1168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  910 SLREQRAAHEEDLQRLQHEKEAawRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQ 989
Cdd:PTZ00121 1169 ARKAEDAKKAEAARKAEEVRKA--EELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  990 ALSLKESEKTALSEKLMGTRHSLAAISLEmERQKRDAQSRQEQDRNTLNALTSELRDlRAQLEEATAAHAQTVKELEERT 1069
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEKKKADEAKKAEEKK-KADEAKKKAEEAKKADEAKKKA 1324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1070 GNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEEL 1149
Cdd:PTZ00121 1325 EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1150 RSA--VKKAESERISLKLANEDKEQKlalleearvsvaKEAGELRASLQEVERSRlEARRELQELRRqmktldSDNGRLG 1227
Cdd:PTZ00121 1405 KKAdeLKKAAAAKKKADEAKKKAEEK------------KKADEAKKKAEEAKKAD-EAKKKAEEAKK------AEEAKKK 1465

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1228 REladlQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEfRARERGLLGSLEEARGAEkrl 1307
Cdd:PTZ00121 1466 AE----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE-EAKKADEAKKAEEAKKAD--- 1537

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1308 ldsarslelrlEAVRAETSELGLRLSAAEgraqglevELARVEAQRRVAEAQlgglRSALRRGLGLGRVssspareapag 1387
Cdd:PTZ00121 1538 -----------EAKKAEEKKKADELKKAE--------ELKKAEEKKKAEEAK----KAEEDKNMALRKA----------- 1583

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1388 gsgdglsspsplEYSPRSQPPSPGLIASPAPPDLDPEAvrdalrdflQELRSAQRERDElkvqtstlSQQLVEMEAERDH 1467
Cdd:PTZ00121 1584 ------------EEAKKAEEARIEEVMKLYEEEKKMKA---------EEAKKAEEAKIK--------AEELKKAEEEKKK 1634

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1468 AASRAKQLQKAVAESEEAwRSADRRLSGAQAELALQEESVRRSKRECRATldqmavlERSLQATESELRASQEKVSKMKA 1547
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEEL-KKAEEENKIKAAEEAKKAEEDKKKAEEAKKA-------EEDEKKAAEALKKEAEEAKKAEE 1706

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|
gi 568931102 1548 TEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRS 1587
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA 1746
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 512-1155 5.54e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 67.94  E-value: 5.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   512 EDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQEL----EKLQAAQEELKRQHNQLEDAQEDSVQEGARARRE 587
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELsaadAAVAKDRSELEALEDQHGAFLDADIETAAADQEQ 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   588 LERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDvlqtekAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSk 667
Cdd:pfam12128  349 LPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK------EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALE- 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   668 mSALNESLAQDKLELN----RLIAQLEEEKVALLGRQQQAEHATTMAVeKQELLEQLRLEQEVERQGlqgslcvaeqaRE 743
Cdd:pfam12128  422 -SELREQLEAGKLEFNeeeyRLKSRLGELKLRLNQATATPELLLQLEN-FDERIERAREEQEAANAE-----------VE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   744 ALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGlavKLAAAEREGRT-- 821
Cdd:pfam12128  489 RLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIG---KVISPELLHRTdl 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   822 ------------LSEEAIRLRLEKEALESSLFDVQrqlaQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKA 889
Cdd:pfam12128  566 dpevwdgsvggeLNLYGVKLDLKRIDVPEWAASEE----ELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREE 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   890 ALDK------ELMTQKLVQAEREAQASLREQRAAH----EEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARME 959
Cdd:pfam12128  642 TFARtalknaRLDLRRLFDEKQSEKDKKNKALAERkdsaNERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQ 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   960 AEKEELSKEIAALQQERDEgllLAESEKQQALSLKESEKTALS------EKLMGTRHSLAAISLEMERQKRDAQSRQEQD 1033
Cdd:pfam12128  722 VVEGALDAQLALLKAAIAA---RRSGAKAELKALETWYKRDLAslgvdpDVIAKLKREIRTLERKIERIAVRRQEVLRYF 798

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1034 RNTLNALTSELRDLRAQLEEataahaqTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDglrrELLEAQRKGRD 1113
Cdd:pfam12128  799 DWYQETWLQRRPRLATQLSN-------IERAISELQQQLARLIADTKLRRAKLEMERKASEKQQV----RLSENLRGLRC 867

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 568931102  1114 SQD--SSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKK 1155
Cdd:pfam12128  868 EMSklATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKK 911
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
835-1343 6.40e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 67.76  E-value: 6.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  835 ALESSLFDVQRQLAQLEARREQLE-ADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAE--REAQASL 911
Cdd:PRK02224  177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEerREELETL 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  912 REQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGqLQQEREELLAR----------MEAEKEELSKEIAALQQERDEGLL 981
Cdd:PRK02224  257 EAEIEDLRETIAETEREREELAEEVRDLRERLEE-LEEERDDLLAEaglddadaeaVEARREELEDRDEELRDRLEECRV 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  982 LAESEKQQALSLKESEKTaLSEKLMGTRHSLAAISLEMERQKRDAQSRQEQdrntLNALTSELRDLRAQLEEATAAHAQT 1061
Cdd:PRK02224  336 AAQAHNEEAESLREDADD-LEERAEELREEAAELESELEEAREAVEDRREE----IEELEEEIEELRERFGDAPVDLGNA 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1062 VKELEERTGNLGRQREacmrEAEELRTQLRVLEDTRDGlRRELLEAQR--------KGRDSQDSSEAHRQEASELRRSLS 1133
Cdd:PRK02224  411 EDFLEELREERDELRE----REAELEATLRTARERVEE-AEALLEAGKcpecgqpvEGSPHVETIEEDRERVEELEAELE 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1134 EGAKEREALRR---SNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVA---KEAGELRASLQEVERSRLEARR 1207
Cdd:PRK02224  486 DLEEEVEEVEErleRAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEelrERAAELEAEAEEKREAAAEAEE 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1208 ELQELRRQMKTLDSDNGRLGRELADLQG-RLALGERTEKESRREALGLRqrllkgesslealKQELQGSQRKLQEQEAEF 1286
Cdd:PRK02224  566 EAEEAREEVAELNSKLAELKERIESLERiRTLLAAIADAEDEIERLREK-------------REALAELNDERRERLAEK 632

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568931102 1287 RARERGLLGS-----LEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLE 1343
Cdd:PRK02224  633 RERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE 694
mukB PRK04863
chromosome partition protein MukB;
450-1235 8.81e-11

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 67.67  E-value: 8.81e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  450 LIHSALHKRQlQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTaASAQAQEDAQREAQRLRSA-NELL 528
Cdd:PRK04863  284 HLEEALELRR-ELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIERYQADlEELE 361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  529 SRekgnLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQE-------------DSVQEGARARRELERSHRQL 595
Cdd:PRK04863  362 ER----LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQaldvqqtraiqyqQAVQALERAKQLCGLPDLTA 437

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  596 EQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRdsLSKMSALNESL 675
Cdd:PRK04863  438 DNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRR--LREQRHLAEQL 515

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  676 AQDKLELNRLIAQLEEEKvALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSE 755
Cdd:PRK04863  516 QQLRMRLSELEQRLRQQQ-RAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQAR 594

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  756 RSHL----------QEQLAQLSRQlSGRDQELEQALRESQRQVEALERAAREkeamakERAGLAVKLAAAEREGRTLS-- 823
Cdd:PRK04863  595 IQRLaarapawlaaQDALARLREQ-SGEEFEDSQDVTEYMQQLLERERELTV------ERDELAARKQALDEEIERLSqp 667

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  824 --EEAIRLRLEKE----ALESSLFD----------------------------VQRQLAQLEARREQL---EADSQAL-- 864
Cdd:PRK04863  668 ggSEDPRLNALAErfggVLLSEIYDdvsledapyfsalygparhaivvpdlsdAAEQLAGLEDCPEDLyliEGDPDSFdd 747

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  865 ------LLAKEtLTGELAGLRQQVTSTEE-----KAALDKELmtqKLVQAEREAQASLREQRAAHEEDLQRLQH------ 927
Cdd:PRK04863  748 svfsveELEKA-VVVKIADRQWRYSRFPEvplfgRAAREKRI---EQLRAEREELAERYATLSFDVQKLQRLHQafsrfi 823

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  928 ----------EKEAAWRELQAERAQLQGQLQQEREELL---ARMEAEKEELSkeiaALQQERDE-GLLLAESEKQQALSL 993
Cdd:PRK04863  824 gshlavafeaDPEAELRQLNRRRVELERALADHESQEQqqrSQLEQAKEGLS----ALNRLLPRlNLLADETLADRVEEI 899

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  994 KESEKTALSEKLMGTRHSLAAISLE---------------MERQKRDAQSRQEQDRNTLNALTsELRDLRAQLeeataAH 1058
Cdd:PRK04863  900 REQLDEAEEAKRFVQQHGNALAQLEpivsvlqsdpeqfeqLKQDYQQAQQTQRDAKQQAFALT-EVVQRRAHF-----SY 973

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1059 AQTVKELEERTGNlgrqreacmreAEELRTQLRVLEDTRDGLRRELLEAQRKGRDS-------QDSSEAHRQEASELRRS 1131
Cdd:PRK04863  974 EDAAEMLAKNSDL-----------NEKLRQRLEQAEQERTRAREQLRQAQAQLAQYnqvlaslKSSYDAKRQMLQELKQE 1042

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1132 LS-------EGAKEREALRRsnEELRSAVKKAESERISLklanedkEQKLALLEEARVSVAKEAGELRASLQEVERSRLE 1204
Cdd:PRK04863 1043 LQdlgvpadSGAEERARARR--DELHARLSANRSRRNQL-------EKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVN 1113

                         890       900       910
                  ....*....|....*....|....*....|.
gi 568931102 1205 ARRELQELRRQMKTLDSDNGRLGRELADLQG 1235
Cdd:PRK04863 1114 AKAGWCAVLRLVKDNGVERRLHRRELAYLSA 1144
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
493-978 2.36e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.83  E-value: 2.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  493 LEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLED 572
Cdd:PRK02224  256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  573 AQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLT 652
Cdd:PRK02224  336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLE 415

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  653 KLRAEEASLRDSLSKMSALNESLAQDKLELNRLiaqLEEEKVALLGRQ-QQAEHATTMA--VEKQELLEQLRLEQEVERQ 729
Cdd:PRK02224  416 ELREERDELREREAELEATLRTARERVEEAEAL---LEAGKCPECGQPvEGSPHVETIEedRERVEELEAELEDLEEEVE 492

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  730 GLQGSLCVAEQAREAlEQQILVLRSERSHLQEQLAQlSRQLSGRDQELEQALREsqrQVEALERAAREKEAMAKEragla 809
Cdd:PRK02224  493 EVEERLERAEDLVEA-EDRIERLEERREDLEELIAE-RRETIEEKRERAEELRE---RAAELEAEAEEKREAAAE----- 562

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  810 vklaaaeregrtlseeairLRLEKEALESSLFDVQRQLAQLEARREQLEadsqalllAKETLTGELAGLRQQVTSTEEKA 889
Cdd:PRK02224  563 -------------------AEEEAEEAREEVAELNSKLAELKERIESLE--------RIRTLLAAIADAEDEIERLREKR 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  890 ALDKELMTQklvqaEREAQASLREQRAAHEEDLQrlqhekEAAWRELQAERAQLQgQLQQEREELLARMEAEKEELSKEI 969
Cdd:PRK02224  616 EALAELNDE-----RRERLAEKRERKRELEAEFD------EARIEEAREDKERAE-EYLEQVEEKLDELREERDDLQAEI 683


                  ....*....
gi 568931102  970 AALQQERDE 978
Cdd:PRK02224  684 GAVENELEE 692
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
728-1322 5.65e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 5.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  728 RQGLQGSLCVAEQAREALEQQILVL-RSERSHlqEQLAQLSRQLSGRDQELEQALRESQ-------RQVEALERAAREKE 799
Cdd:PRK03918  133 RQGEIDAILESDESREKVVRQILGLdDYENAY--KNLGEVIKEIKRRIERLEKFIKRTEnieelikEKEKELEEVLREIN 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  800 AMAKERAGLAVKLAAAEREGRTLS---EEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALllakETLTGELA 876
Cdd:PRK03918  211 EISSELPELREELEKLEKEVKELEelkEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL----EEKVKELK 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  877 GLRQQVTSTEEKAALDKELmTQKLVQAEREAqASLREQRAAHEEDLQRLQhEKEAAWRELQAERAQLQGQLQ--QEREEL 954
Cdd:PRK03918  287 ELKEKAEEYIKLSEFYEEY-LDELREIEKRL-SRLEEEINGIEERIKELE-EKEERLEELKKKLKELEKRLEelEERHEL 363

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  955 LAR---MEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRD-----A 1026
Cdd:PRK03918  364 YEEakaKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgR 443

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1027 QSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREacMREAEELRTQLRVLEDTRDGLRRELLE 1106
Cdd:PRK03918  444 ELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKELAEQLKELEEKLKKYNLEELE 521

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1107 AQRKgrdsqdsseahrqEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAK 1186
Cdd:PRK03918  522 KKAE-------------EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVE 588

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1187 EAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKE--------SRREALGLRQRL 1258
Cdd:PRK03918  589 ELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKEleelekkySEEEYEELREEY 668

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568931102 1259 LKGESSLEALKQELQGSQRKLQEQEAEFRARERgllgSLEEARGAEKRLLDSARSLElRLEAVR 1322
Cdd:PRK03918  669 LELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKLEKALE-RVEELR 727
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
737-1291 7.10e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.29  E-value: 7.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  737 VAEQAREALEQ-QILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVkLAAA 815
Cdd:PRK02224  181 VLSDQRGSLDQlKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELET-LEAE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  816 EREGRTLSEEAIRlrlEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLrqqvtsTEEKAALDKEL 895
Cdd:PRK02224  260 IEDLRETIAETER---EREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREEL------EDRDEELRDRL 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  896 MTQKLVQAEREAQA-SLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQgqlqqEREELLARMEAEKEELSKEIAALQQ 974
Cdd:PRK02224  331 EECRVAAQAHNEEAeSLREDADDLEERAEELREEAAELESELEEAREAVE-----DRREEIEELEEEIEELRERFGDAPV 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  975 ERDEglllAESEkqqaLSLKESEKTALSEKLMGTRHSL--AAISLEMERQKRDA---------------QSRQEQDRNTL 1037
Cdd:PRK02224  406 DLGN----AEDF----LEELREERDELREREAELEATLrtARERVEEAEALLEAgkcpecgqpvegsphVETIEEDRERV 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1038 NALTSELRDLRAQLEEATAAH--AQTVKELEERTGNLGRQREACMR-------EAEELRTQLRVLEDTRDGLRRELLEAQ 1108
Cdd:PRK02224  478 EELEAELEDLEEEVEEVEERLerAEDLVEAEDRIERLEERREDLEEliaerreTIEEKRERAEELRERAAELEAEAEEKR 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1109 RKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSnEELRSAVKKAESERISLKlaneDKEQKLALLEEARVSVAKEA 1188
Cdd:PRK02224  558 EAAAEAEEEAEEAREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLR----EKREALAELNDERRERLAEK 632

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1189 GELRASLQ-EVERSRLE-ARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRRealgLRQRLLKGESSLE 1266
Cdd:PRK02224  633 RERKRELEaEFDEARIEeAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE----LRERREALENRVE 708

                         570       580
                  ....*....|....*....|....*
gi 568931102 1267 ALkQELQGSQRKLQEQEAEFRARER 1291
Cdd:PRK02224  709 AL-EALYDEAEELESMYGDLRAELR 732
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
458-964 7.78e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.17  E-value: 7.78e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  458 RQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQ-EDAQREAQRLRSANELLSREKGNLT 536
Cdd:COG4913   286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLE 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  537 HSLQVTQQQAKELRQELEKLQ----AAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEV 612
Cdd:COG4913   366 ALLAALGLPLPASAEEFAALRaeaaALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL 445

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  613 REAL--SCAILQRDV--------LQTEKAEVAEALTKAEAGRA--------QLELSLTKLRAEEASLRDSLSKMSALNES 674
Cdd:COG4913   446 RDALaeALGLDEAELpfvgelieVRPEEERWRGAIERVLGGFAltllvppeHYAAALRWVNRLHLRGRLVYERVRTGLPD 525

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  675 LAQDKLELNRLIAQLEEEKVALLG--RQQQAEHATTMAVEKQELLEQLRleQEVERQGL-QGSLCVAEQAREALEQQILV 751
Cdd:COG4913   526 PERPRLDPDSLAGKLDFKPHPFRAwlEAELGRRFDYVCVDSPEELRRHP--RAITRAGQvKGNGTRHEKDDRRRIRSRYV 603

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  752 LRSERshlQEQLAQLSRQLsgrdQELEQALRESQRQVEALERAAREKEAMAKERAGLAvKLAAAEREGRTLSEEAIRLRL 831
Cdd:COG4913   604 LGFDN---RAKLAALEAEL----AELEEELAEAEERLEALEAELDALQERREALQRLA-EYSWDEIDVASAEREIAELEA 675

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  832 EKEALESSLFDvqrqLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASL 911
Cdd:COG4913   676 ELERLDASSDD----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568931102  912 REQRAAHEEDLQRlqhekEAAWRELQAERAQLQGQLQQEREELLARMEAEKEE 964
Cdd:COG4913   752 EERFAAALGDAVE-----RELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
PTZ00121 PTZ00121
MAEBL; Provisional
 461-1004 1.19e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 1.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  461 QVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQE----DAQREAQRLRSANELLSREKGNLT 536
Cdd:PTZ00121 1225 KAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEarkaDELKKAEEKKKADEAKKAEEKKKA 1304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  537 HSLQVTQQQAK---ELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRS-------GLT 606
Cdd:PTZ00121 1305 DEAKKKAEEAKkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEeakkkadAAK 1384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  607 KELVEVREALScaiLQRDVLQTEKAevAEALTKAEAGRAQLELSLTKL----RAEEASLRDSLSKMSALNESLAQDKLEL 682
Cdd:PTZ00121 1385 KKAEEKKKADE---AKKKAEEDKKK--ADELKKAAAAKKKADEAKKKAeekkKADEAKKKAEEAKKADEAKKKAEEAKKA 1459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  683 NRLIAQLEEEKVALLGRQQ-----QAEHATTMAVEKQELLEQLRLEQEVERQGLQgsLCVAEQAREALEQQilvlRSERS 757
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKaeeakKADEAKKKAEEAKKKADEAKKAAEAKKKADE--AKKAEEAKKADEAK----KAEEA 1533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  758 HLQEQLAQLSRQLSGRD-------------QELEQALRESQRQVEALERAAREKEAmakERAGLAVKLAAAEREGRTLSE 824
Cdd:PTZ00121 1534 KKADEAKKAEEKKKADElkkaeelkkaeekKKAEEAKKAEEDKNMALRKAEEAKKA---EEARIEEVMKLYEEEKKMKAE 1610

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  825 EAIRLRLEKEALES--SLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAAL------DKELM 896
Cdd:PTZ00121 1611 EAKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkaeeDEKKA 1690

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  897 TQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQER 976
Cdd:PTZ00121 1691 AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770

                         570       580
                  ....*....|....*....|....*...
gi 568931102  977 DEGLLLAESEKQQALSLKESEKTALSEK 1004
Cdd:PTZ00121 1771 EEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 547-1285 1.36e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 1.36e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   547 KELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVL 626
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   627 QTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALN-ESLAQDKLELNRLIAQLEEEKVALLGRQQQAEH 705
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEeEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   706 ATTMAVEKQELLEQLRLEQEVERQGLQGSlcvAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQ 785
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEE---EEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   786 RQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALL 865
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   866 LAKETLTGELAGLRQQVT-STEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQ 944
Cdd:pfam02463  486 LELLLSRQKLEERSQKESkARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQK 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   945 GQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSL------AAISLE 1018
Cdd:pfam02463  566 LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEltklkeSAKAKE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1019 MERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRD 1098
Cdd:pfam02463  646 SGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLAD 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1099 GLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEG---AKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLA 1175
Cdd:pfam02463  726 RVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKeeeKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRA 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1176 LLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLR 1255
Cdd:pfam02463  806 LEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLK 885

                          730       740       750
                   ....*....|....*....|....*....|
gi 568931102  1256 QRLLKGESSLEALKQELQGSQRKLQEQEAE 1285
Cdd:pfam02463  886 DELESKEEKEKEEKKELEEESQKLNLLEEK 915
PTZ00121 PTZ00121
MAEBL; Provisional
 874-1650 2.13e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.24  E-value: 2.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  874 ELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERaqlqGQLQQEREE 953
Cdd:PTZ00121 1031 ELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF----GKAEEAKKT 1106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  954 LLARMEAEKEELSKEIAALQQERDEGLLLAEsekqQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQD 1033
Cdd:PTZ00121 1107 ETGKAEEARKAEEAKKKAEDARKAEEARKAE----DARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAAR 1182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1034 RNTLNALTSELRdlraQLEEATAAHAQTVKELEERTGNLGRQREAcmREAEELRTQLRVLEDTRDGLRRELLEAQRKGRD 1113
Cdd:PTZ00121 1183 KAEEVRKAEELR----KAEDARKAEAARKAEEERKAEEARKAEDA--KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1114 SQDSSEAHRQeaselRRSLSEGAKERealrRSNEELRSA--VKKAESERISLKLANEDKEQKLAllEEARvsvakEAGEL 1191
Cdd:PTZ00121 1257 FEEARMAHFA-----RRQAAIKAEEA----RKADELKKAeeKKKADEAKKAEEKKKADEAKKKA--EEAK-----KADEA 1320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1192 RASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSlEALKQE 1271
Cdd:PTZ00121 1321 KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA-DEAKKK 1399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1272 LQGSQRKLQE--QEAEFRARERGLLGSLEEARGAE---KRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEvel 1346
Cdd:PTZ00121 1400 AEEDKKKADElkKAAAAKKKADEAKKKAEEKKKADeakKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK--- 1476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1347 ARVEAQRRVAEAQlgglrsalRRGLGLGRVSSSPAREAPAGGSGDGLSSPsplEYSPRSQPPSPGLIASPAPPDLDPEAV 1426
Cdd:PTZ00121 1477 KKAEEAKKADEAK--------KKAEEAKKKADEAKKAAEAKKKADEAKKA---EEAKKADEAKKAEEAKKADEAKKAEEK 1545

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1427 RDAlrdflQELRSAQRERdelKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEES 1506
Cdd:PTZ00121 1546 KKA-----DELKKAEELK---KAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1507 VR------RSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEA-KLESDKRRLKEVLDASESRSIKLELQRRA 1579
Cdd:PTZ00121 1618 AKikaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAkKAEEDKKKAEEAKKAEEDEKKAAEALKKE 1697

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568931102 1580 LEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQltvERLSGALAKVEESEGNlrsKVQSL 1650
Cdd:PTZ00121 1698 AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE---DKKKAEEAKKDEEEKK---KIAHL 1762
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
544-1144 2.61e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.63  E-value: 2.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  544 QQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSvQEGARARRELERSHRQLEQLEVKRsgltkelvevrealscAILQR 623
Cdd:COG4913   228 DALVEHFDDLERAHEALEDAREQIELLEPIRELA-ERYAAARERLAELEYLRAALRLWF----------------AQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  624 DVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDslskmsALNESLAQDKLELNRLIAQLEEEKVALLGRQQQA 703
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEA------QIRGNGGDRLEQLEREIERLERELEERERRRARL 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  704 ehattmavekQELLEQLRLEQEVERQGLqgslcvaEQAREALEQQILVLRSERSHLQEQLAQLSRQLsgrdQELEQALRE 783
Cdd:COG4913   365 ----------EALLAALGLPLPASAEEF-------AALRAEAAALLEALEEELEALEEALAEAEAAL----RDLRRELRE 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  784 SQRQVEALE-RAAREKEAMAKERAGLAVKLAAAEREGRTLSEEaIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQ 862
Cdd:COG4913   424 LEAEIASLErRKSNIPARLLALRDALAEALGLDEAELPFVGEL-IEVRPEEERWRGAIERVLGGFALTLLVPPEHYAAAL 502

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  863 AlLLAKETLTGELAGLR-QQVTSTEEKAALDKELMTQKLVQAEREAQASLRE---QRAAHE--EDLQRLQHEKEAAWREL 936
Cdd:COG4913   503 R-WVNRLHLRGRLVYERvRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAelgRRFDYVcvDSPEELRRHPRAITRAG 581

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  937 Q----AERAQLQGQ--------LQQEREELLARMEAEKEELSKEIAALQQERDeglllaesEKQQALSLKESEKTALSEK 1004
Cdd:COG4913   582 QvkgnGTRHEKDDRrrirsryvLGFDNRAKLAALEAELAELEEELAEAEERLE--------ALEAELDALQERREALQRL 653

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1005 LMGTRHSLAAISLEMERQkrdaqsRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGR---QREACMR 1081
Cdd:COG4913   654 AEYSWDEIDVASAEREIA------ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRlekELEQAEE 727

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568931102 1082 EAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSL-SEGAKEREALRR 1144
Cdd:COG4913   728 ELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALrARLNRAEEELER 791
mukB PRK04863
chromosome partition protein MukB;
487-947 9.08e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 60.74  E-value: 9.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  487 EGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVT---QQQAKELRQELEKLQAAQEEL 563
Cdd:PRK04863  278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAAsdhLNLVQTALRQQEKIERYQADL 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  564 KRQHNQLEDAQEDSvqegARARRELERSHRQLEQLEVKRSGLTKELVEVREALscailqrDVLQTEKAEVAEALTKAEAG 643
Cdd:PRK04863  358 EELEERLEEQNEVV----EEADEQQEENEARAEAAEEEVDELKSQLADYQQAL-------DVQQTRAIQYQQAVQALERA 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  644 RAQLELSltklraeeaslrdslskmsalneSLAQDKLE--LNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLR 721
Cdd:PRK04863  427 KQLCGLP-----------------------DLTADNAEdwLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVR 483

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  722 -LEQEVERQGLQgslcvaEQAREALEQqilvLRSERsHLQEQLAQLSRQLSgrdqELEQALRESQRQVEALERAAREKEA 800
Cdd:PRK04863  484 kIAGEVSRSEAW------DVARELLRR----LREQR-HLAEQLQQLRMRLS----ELEQRLRQQQRAERLLAEFCKRLGK 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  801 MAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEalesslfDVQRQLAQLEARREQLEADSQALLLAKETltgeLAGLRQ 880
Cdd:PRK04863  549 NLDDEDELEQLQEELEARLESLSESVSEARERRM-------ALRQQLEQLQARIQRLAARAPAWLAAQDA----LARLRE 617

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  881 QVTSTEEKAALDKELMTQKLVQaEREAQAS---LREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQL 947
Cdd:PRK04863  618 QSGEEFEDSQDVTEYMQQLLER-ERELTVErdeLAARKQALDEEIERLSQPGGSEDPRLNALAERFGGVL 686
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1424-1900 9.10e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.70  E-value: 9.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1424 EAVRDALRDFLqelrsAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSAD-RRLSGAQAELAL 1502
Cdd:COG4913   275 EYLRAALRLWF-----AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIER 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1503 QEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVskmKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEG 1582
Cdd:COG4913   350 LERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA---AALLEALEEELEALEEALAEAEAALRDLRRELRELEA 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1583 ELQRSRLGLGDREAHAQALQDRvdsLQRQVADSEVKA------------------------GTLQLTV----ERLSGALA 1634
Cdd:COG4913   427 EIASLERRKSNIPARLLALRDA---LAEALGLDEAELpfvgelievrpeeerwrgaiervlGGFALTLlvppEHYAAALR 503

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1635 KVEESEGNLR---SKVQSLTDALTQSSASLSSTQDKnlhlqkaLSTCEHD-----RQVLQERLDAAR----QALSEARR- 1701
Cdd:COG4913   504 WVNRLHLRGRlvyERVRTGLPDPERPRLDPDSLAGK-------LDFKPHPfrawlEAELGRRFDYVCvdspEELRRHPRa 576

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1702 --------QSSSLGE-------------------QVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEgEAMALRSVQK 1754
Cdd:COG4913   577 itragqvkGNGTRHEkddrrrirsryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQE-RREALQRLAE 655

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1755 LQEErrllQERLGSLQRALAQLEAEKRDLERSALQFDkdrvALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAEL 1834
Cdd:COG4913   656 YSWD----EIDVASAEREIAELEAELERLDASSDDLA----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE 727

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568931102 1835 DLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLE------LQQEVERLRSAQVQTERTLEARERAHRQR 1900
Cdd:COG4913   728 ELDELQDRLEAAEDLARLELRALLEERFAAALGDAVErelrenLEERIDALRARLNRAEEELERAMRAFNRE 799
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1120-1649 1.22e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1120 AHRQEASELRRSLSEGAKEREAL---RRSNEELRSAVKKAES-ERISLKLANEDKEQKLALLEEARVSVAKEAGELRASL 1195
Cdd:COG4913   232 EHFDDLERAHEALEDAREQIELLepiRELAERYAAARERLAElEYLRAALRLWFAQRRLELLEAELEELRAELARLEAEL 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1196 QEVERSRLEARRELQELRRQMKTLDSDN-GRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQG 1274
Cdd:COG4913   312 ERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1275 SQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELR-------LEAVRAETSElGLRLSAAEGRAQGLEVELA 1347
Cdd:COG4913   392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRksniparLLALRDALAE-ALGLDEAELPFVGELIEVR 470

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1348 RVEAQ-RRVAEAQLGGLRSAL-------------------RRGLGLGRVSSSPAREAPAGGSGDGLS-----SPSPLEYS 1402
Cdd:COG4913   471 PEEERwRGAIERVLGGFALTLlvppehyaaalrwvnrlhlRGRLVYERVRTGLPDPERPRLDPDSLAgkldfKPHPFRAW 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1403 PRSQPPSPGLIASPAppdlDPEAVRDALRDFLQE-LRSAQRERDELKVQTSTLSQQLVEMEAERdhaasRAKQLQKAVAE 1481
Cdd:COG4913   551 LEAELGRRFDYVCVD----SPEELRRHPRAITRAgQVKGNGTRHEKDDRRRIRSRYVLGFDNRA-----KLAALEAELAE 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1482 SEEAWRSADRRLSGAQAELALQEESVRRSKR--ECRATLDQMAVLERSLQATESE---LRASQEKVSKMKATEAKLESDK 1556
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQERREALQRlaEYSWDEIDVASAEREIAELEAElerLDASSDDLAALEEQLEELEAEL 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1557 RRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHA-QALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAK 1635
Cdd:COG4913   702 EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLArLELRALLEERFAAALGDAVERELRENLEERIDALRAR 781

                         570
                  ....*....|....
gi 568931102 1636 VEESEGNLRSKVQS 1649
Cdd:COG4913   782 LNRAEEELERAMRA 795
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
995-1357 2.07e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  995 ESEKTALSEKLMGTRHSLAAISLEMER---QKRDAQ----------SRQEQDRNTLNALTSELRDLRAQLEEAT---AAH 1058
Cdd:PRK02224  198 EKEEKDLHERLNGLESELAELDEEIERyeeQREQARetrdeadevlEEHEERREELETLEAEIEDLRETIAETErerEEL 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1059 AQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKE 1138
Cdd:PRK02224  278 AEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEER 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1139 REALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKT 1218
Cdd:PRK02224  358 AEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRT 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1219 LDsDNGRLGRELADLQGRLALGERTEKESRREALG-LRQRLLKGESSLEALKQELQGSQRKLQEQEaEFRARERGLLGSL 1297
Cdd:PRK02224  438 AR-ERVEEAEALLEAGKCPECGQPVEGSPHVETIEeDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLE 515

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568931102 1298 EEARGAEKRLLDSARSLE---LRLEAVRAETSElgLRLSAAEGRAQGLEVELARVEAQRRVAE 1357
Cdd:PRK02224  516 ERREDLEELIAERRETIEekrERAEELRERAAE--LEAEAEEKREAAAEAEEEAEEAREEVAE 576
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 465-1207 2.13e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 2.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   465 MRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQ 544
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   545 QAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELER-SHRQLEQLEVKRSGLTKELVEVREALSCAILQR 623
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeSERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   624 DVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQA 703
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   704 EHATTMAVEKQELLEQLRLEQ------------------EVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQ 765
Cdd:pfam02463  496 EERSQKESKARSGLKVLLALIkdgvggriisahgrlgdlGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   766 LSRQLSGRDqELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQR 845
Cdd:pfam02463  576 GARKLRLLI-PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   846 QLAQLEARR-------EQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAH 918
Cdd:pfam02463  655 EEGLAEKSEvkaslseLTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   919 EEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEK 998
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   999 TALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREA 1078
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1079 CMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAES 1158
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102  1159 ERISLKLANEDKEQ-------KLALLEEARVSVAKEAGELRASLQEVERSRLEARR 1207
Cdd:pfam02463  975 VNLMAIEEFEEKEErynkdelEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSIN 1030
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
588-978 2.64e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 59.01  E-value: 2.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  588 LERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLS- 666
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQl 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  667 -----KMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQA 741
Cdd:COG4717   128 lplyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  742 REALEQQILVLRSERSHLQEQLAQLSRQLsgRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRT 821
Cdd:COG4717   208 LAELEEELEEAQEELEELEEELEQLENEL--EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  822 LSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLV 901
Cdd:COG4717   286 LALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568931102  902 QAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEA-EKEELSKEIAALQQERDE 978
Cdd:COG4717   366 EELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAlDEEELEEELEELEEELEE 443
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
607-1217 3.81e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 3.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  607 KELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLI 686
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLE 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  687 AQLEEEKVALLGRQQQAEhattmavEKQELLEQLRlEQEVERQGLQGSlcvaeqarealEQQILVLRSERSHLQEQLAQL 766
Cdd:PRK03918  252 GSKRKLEEKIRELEERIE-------ELKKEIEELE-EKVKELKELKEK-----------AEEYIKLSEFYEEYLDELREI 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  767 SRQLSgrdqELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLsEEAIRLRLEKEALESSLFDVQrq 846
Cdd:PRK03918  313 EKRLS----RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY-EEAKAKKEELERLKKRLTGLT-- 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  847 laqlearREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAAlDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQ 926
Cdd:PRK03918  386 -------PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK-ELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEY 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  927 HEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELS-KEIAALQQERDEGLLLAESEKqqaLSLKESEKTALSEKL 1005
Cdd:PRK03918  458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKlKELAEQLKELEEKLKKYNLEE---LEKKAEEYEKLKEKL 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1006 MGTRHSLAAISLEMERQKrDAQSRQEQDRNTLNALTSELRDLRAQLEEATaahAQTVKELEERTGNLGRQREACMrEAEE 1085
Cdd:PRK03918  535 IKLKGEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKELEELG---FESVEELEERLKELEPFYNEYL-ELKD 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1086 LRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEgaKEREALRRSNEELRSAVKKAESErislkl 1165
Cdd:PRK03918  610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLELSRELAGLRAE------ 681

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568931102 1166 anedkeqkLALLEEARVSVAKEAGELRASLQEVERSRLE------ARRELQELRRQMK 1217
Cdd:PRK03918  682 --------LEELEKRREEIKKTLEKLKEELEEREKAKKEleklekALERVEELREKVK 731
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 691-1282 4.32e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 58.44  E-value: 4.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   691 EEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQL 770
Cdd:TIGR00618  163 KEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSH 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   771 SGRDQELEQALRESQRQVEALERAAREKEAMAKERAglavklAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQL 850
Cdd:TIGR00618  243 AYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAV------LEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   851 EARREQLEadsqalllakETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRL---QH 927
Cdd:TIGR00618  317 QSKMRSRA----------KLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIhtlQQ 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   928 EKEAAWRELQAErAQLQGQLQQEREELLARMEAEKEELSKEIAA-----LQQERDEGLLLAESEKQQALSLKESEKTALS 1002
Cdd:TIGR00618  387 QKTTLTQKLQSL-CKELDILQREQATIDTRTSAFRDLQGQLAHAkkqqeLQQRYAELCAAAITCTAQCEKLEKIHLQESA 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1003 EKLMGTRHSLA---AISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQT--VKELEERTGNLGRQRE 1077
Cdd:TIGR00618  466 QSLKEREQQLQtkeQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTrrMQRGEQTYAQLETSEE 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1078 ACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSN-EELRSAVKKA 1156
Cdd:TIGR00618  546 DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQhALLRKLQPEQ 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1157 ESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGR 1236
Cdd:TIGR00618  626 DLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTL 705

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 568931102  1237 LALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQ 1282
Cdd:TIGR00618  706 LRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQ 751
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 458-1156 6.70e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 58.04  E-value: 6.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  458 RQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQR-------------EAQRLRSA 524
Cdd:COG3096   352 YQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTraiqyqqavqaleKARALCGL 431

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  525 NELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARAR-----RELERSHRQLEQLE 599
Cdd:COG3096   432 PDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQawqtaRELLRRYRSQQALA 511

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  600 VKRSGLTKELVEVREALScailQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDK 679
Cdd:COG3096   512 QRLQQLRAQLAELEQRLR----QQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  680 LELNRLIAQLEEEKVALLGRQQQAEHATTMAVEK-----------QELLEQLRlEQEVERQGLQgslcvaeQAREALEQQ 748
Cdd:COG3096   588 EQLRARIKELAARAPAWLAAQDALERLREQSGEAladsqevtaamQQLLERER-EATVERDELA-------ARKQALESQ 659

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  749 ILVLRSERSHLQEQLAQLS-------------------------------------------RQLSGRD----------- 774
Cdd:COG3096   660 IERLSQPGGAEDPRLLALAerlggvllseiyddvtledapyfsalygparhaivvpdlsavkEQLAGLEdcpedlylieg 739

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  775 ------------QELEQA--LRESQRQ--------VEALERAAREK--EAMAKERAGLAVKLAAAEREGRTLSeeaiRLR 830
Cdd:COG3096   740 dpdsfddsvfdaEELEDAvvVKLSDRQwrysrfpeVPLFGRAAREKrlEELRAERDELAEQYAKASFDVQKLQ----RLH 815

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  831 LEKEAL-------------ESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTeekAALDKELMT 897
Cdd:COG3096   816 QAFSQFvgghlavafapdpEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQA---NLLADETLA 892

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  898 QKLVQAEREAQASLREQR--AAHEEDLQRLQhEKEAAWRELQAERAQLQGQLQQEREELlarmeaekEELSKEIAALQQE 975
Cdd:COG3096   893 DRLEELREELDAAQEAQAfiQQHGKALAQLE-PLVAVLQSDPEQFEQLQADYLQAKEQQ--------RRLKQQIFALSEV 963

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  976 RDEGLLLAESEKQQALslkeSEKTALSEKLmgtRHSLAaislEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEeat 1055
Cdd:COG3096   964 VQRRPHFSYEDAVGLL----GENSDLNEKL---RARLE----QAEEARREAREQLRQAQAQYSQYNQVLASLKSSRD--- 1029

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1056 aAHAQTVKELEERTGNLGRQREACMREA-------------------EELRTQLRVLEDTRDGLRRELLEAQRKGRDSQD 1116
Cdd:COG3096  1030 -AKQQTLQELEQELEELGVQADAEAEERarirrdelheelsqnrsrrSQLEKQLTRCEAEMDSLQKRLRKAERDYKQERE 1108

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*
gi 568931102 1117 SSEAHRQEASELRRSLSEGAKEREALRR-----SNEELRSAVKKA 1156
Cdd:COG3096  1109 QVVQAKAGWCAVLRLARDNDVERRLHRRelaylSADELRSMSDKA 1153
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 701-1348 7.18e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.93  E-value: 7.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   701 QQAEHATTMAVEKQEL------LEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVL---RSERSHL-QEQLAQLSRQL 770
Cdd:pfam12128  277 RQEERQETSAELNQLLrtlddqWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFldaDIETAAAdQEQLPSWQSEL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   771 SGRDQELEqALRESQRQVEAL--ERAAREKEAMAKERAGLAVKLAAaEREGRTLSEEAIRLRLEkeALESSLFDvQRQLA 848
Cdd:pfam12128  357 ENLEERLK-ALTGKHQDVTAKynRRRSKIKEQNNRDIAGIKDKLAK-IREARDRQLAVAEDDLQ--ALESELRE-QLEAG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   849 QLEARREQLEADSQAlllaketltGELAGLRQQVTSTEEKaaLDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHE 928
Cdd:pfam12128  432 KLEFNEEEYRLKSRL---------GELKLRLNQATATPEL--LLQLENFDERIERAREEQEAANAEVERLQSELRQARKR 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   929 KEAAWRELQAERA---QLQGQLQQEREELLARMEAEKEELSKEIAALQQerDEGLLLAesekqQALSLKESEKTALSEKL 1005
Cdd:pfam12128  501 RDQASEALRQASRrleERQSALDELELQLFPQAGTLLHFLRKEAPDWEQ--SIGKVIS-----PELLHRTDLDPEVWDGS 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1006 MGTRHSLAAISLEMERQkrdaqsrqeqDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEE 1085
Cdd:pfam12128  574 VGGELNLYGVKLDLKRI----------DVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETF 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1086 LRTqlrVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLsegAKEREALRRSNEELRSAVKKAESErislkl 1165
Cdd:pfam12128  644 ART---ALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSL---EAQLKQLDKKHQAWLEEQKEQKRE------ 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1166 ANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRElqELRRQMKTLDSDN---GRLGRELADLQGRLALGER 1242
Cdd:pfam12128  712 ARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALET--WYKRDLASLGVDPdviAKLKREIRTLERKIERIAV 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1243 TEKESRR-------EALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLE 1315
Cdd:pfam12128  790 RRQEVLRyfdwyqeTWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869

                          650       660       670
                   ....*....|....*....|....*....|...
gi 568931102  1316 LRLEAVRAETSELGLRLSAAEGRAQGLEVELAR 1348
Cdd:pfam12128  870 SKLATLKEDANSEQAQGSIGERLAQLEDLKLKR 902
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1424-1917 7.50e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 7.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1424 EAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEawrsadrRLSGAQAELALQ 1503
Cdd:PRK02224  233 RETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE-------ERDDLLAEAGLD 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1504 EesvrrskrecratLDQMAVLERsLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGE 1583
Cdd:PRK02224  306 D-------------ADAEAVEAR-REELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1584 LQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSA---- 1659
Cdd:PRK02224  372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAllea 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1660 -----------------SLSSTQDKNLHLQKALSTCEHDRQVLQERLDAArQALSEARRQSSSLGEQVQTLrGELASLEL 1722
Cdd:PRK02224  452 gkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDL-EELIAERR 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1723 QRGDAEGQLQQLQQALRQRQEGEAMALR-SVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDK--------- 1792
Cdd:PRK02224  530 ETIEEKRERAEELRERAAELEAEAEEKReAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAiadaedeie 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1793 ---DRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRtLTGAELDLAEAQQQIQHLEAQVDvALEGNHNPVQPEAGEQQ 1869
Cdd:PRK02224  610 rlrEKREALAELNDERRERLAEKRERKRELEAEFDEAR-IEEAREDKERAEEYLEQVEEKLD-ELREERDDLQAEIGAVE 687

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 568931102 1870 LELqQEVERLRSAQVQTERTLEARERAHRQrVSGLEEQVSTLKAQLHQ 1917
Cdd:PRK02224  688 NEL-EELEELRERREALENRVEALEALYDE-AEELESMYGDLRAELRQ 733
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 489-692 7.59e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 7.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  489 ERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHN 568
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  569 QLEDAQEDSVQEGARARR--------------ELERSHRQLEQLEVKRSGLTKELVEVREALScaiLQRDVLQTEKAEVA 634
Cdd:COG4942   101 AQKEELAELLRALYRLGRqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELA---ALRAELEAERAELE 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568931102  635 EALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEE 692
Cdd:COG4942   178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 473-1285 7.81e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 57.88  E-value: 7.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   473 QELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQE 552
Cdd:pfam01576   18 KERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNE 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   553 LEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKE--------------LVEVREALSC 618
Cdd:pfam01576   98 KKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKErklleeriseftsnLAEEEEKAKS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   619 AILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNEslaqdklELNRLIAQLEEEKVALLG 698
Cdd:pfam01576  178 LSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIA-------ELRAQLAKKEEELQAALA 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   699 RQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSE--------------RSHLQEQLA 764
Cdd:pfam01576  251 RLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEledtldttaaqqelRSKREQEVT 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   765 QLSRQLSGRDQELEQALRESQRQ--------VEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEAL 836
Cdd:pfam01576  331 ELKKALEEETRSHEAQLQEMRQKhtqaleelTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKL 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   837 ESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQ-VTSTEEKAALDKELM-TQKLVQAEREAQASLREQ 914
Cdd:pfam01576  411 EGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKnIKLSKDVSSLESQLQdTQELLQEETRQKLNLSTR 490

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   915 RAAHEED---LQRLQHEKEAAWRELQAERAQLQGQL------------------------QQEREELLARME---AEKEE 964
Cdd:pfam01576  491 LRQLEDErnsLQEQLEEEEEAKRNVERQLSTLQAQLsdmkkkleedagtlealeegkkrlQRELEALTQQLEekaAAYDK 570

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   965 LSKEIAALQQERDEGLLLAESEKQQALSLKE---------SEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRN 1035
Cdd:pfam01576  571 LEKTKNRLQQELDDLLVDLDHQRQLVSNLEKkqkkfdqmlAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALE 650

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1036 TLNALTSELRDLRAQLEEATAAHAQTVKELEErtgnLGRQREACMREAEELRTQLRVLED----TRDGLRRELLEAQRKG 1111
Cdd:pfam01576  651 AKEELERTNKQLRAEMEDLVSSKDDVGKNVHE----LERSKRALEQQVEEMKTQLEELEDelqaTEDAKLRLEVNMQALK 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1112 RDSQDSSEAHRQEASELRRSLSEGAKEREALRrsnEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGEL 1191
Cdd:pfam01576  727 AQFERDLQARDEQGEEKRRQLVKQVRELEAEL---EDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKL 803

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1192 RASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQE 1271
Cdd:pfam01576  804 QAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDE 883

                          890
                   ....*....|....
gi 568931102  1272 LQGSQRKLQEQEAE 1285
Cdd:pfam01576  884 KRRLEARIAQLEEE 897
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 535-774 1.81e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  535 LTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVRE 614
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  615 ALscAILQRDvLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKV 694
Cdd:COG4942    91 EI--AELRAE-LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  695 ALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRD 774
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1020-1238 2.02e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1020 ERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDG 1099
Cdd:COG4942    26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1100 LRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEE 1179
Cdd:COG4942   106 LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102 1180 ARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLA 1238
Cdd:COG4942   186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1646-1924 2.39e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 2.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1646 KVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQ-ERLDAARQ----ALSEARRQSSSLGEQVQTLRGELASL 1720
Cdd:COG1196   214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAElEELEAELAeleaELEELRLELEELELELEEAQAEEYEL 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1721 ELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKT 1800
Cdd:COG1196   294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1801 LDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLR 1880
Cdd:COG1196   374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 568931102 1881 SAqvQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELRRSSA 1924
Cdd:COG1196   454 LE--EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 749-1007 3.48e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  749 ILVLRSERSHLQEQLAQLSRQLSGRDQELEQALREsqrqveaLERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAir 828
Cdd:COG4942     8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKE-------LAALKKEEKALLKQLAALERRIAALARRIRALEQEL-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  829 lrlekEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLtGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQ 908
Cdd:COG4942    79 -----AALEAELAELEKEIAELRAELEAQKEELAELLRALYRL-GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  909 ASLREQRA---AHEEDLQRLQHEKEAAWRELQAERAQLQgQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAES 985
Cdd:COG4942   153 EELRADLAelaALRAELEAERAELEALLAELEEERAALE-ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250       260
                  ....*....|....*....|..
gi 568931102  986 EKQQALSLKESEKTALSEKLMG 1007
Cdd:COG4942   232 LEAEAAAAAERTPAAGFAALKG 253
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 525-997 4.01e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 4.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   525 NELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEdsvqegaRARRELERSHRQLEQLEVKRSG 604
Cdd:TIGR04523  213 NKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN-------KIKKQLSEKQKELEQNNKKIKE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   605 LTKELVEVREALScaILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNR 684
Cdd:TIGR04523  286 LEKQLNQLKSEIS--DLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   685 LIAQlEEEKVALLGRQQQAEHATTMAVEKQ-ELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQL 763
Cdd:TIGR04523  364 ELEE-KQNEIEKLKKENQSYKQEIKNLESQiNDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEI 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   764 AQLSRQLSGRD---QELEQALRESQRQVEALERAAREKEAmakeraglavKLAAAEREGRTLSEEAIRLRLEKEALESSL 840
Cdd:TIGR04523  443 KDLTNQDSVKEliiKNLDNTRESLETQLKVLSRSINKIKQ----------NLEQKQKELKSKEKELKKLNEEKKELEEKV 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   841 FDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKElmTQKLVQAEREAQASLREQRAAhEE 920
Cdd:TIGR04523  513 KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEK--NKEIEELKQTQKSLKKKQEEK-QE 589

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568931102   921 DLQRLQHEKEAAWRELqAERAQLQGQLQQEREELlarmEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESE 997
Cdd:TIGR04523  590 LIDQKEKEKKDLIKEI-EEKEKKISSLEKELEKA----KKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKW 661
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 541-1218 5.22e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 5.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   541 VTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARAR------RELERSHRQLEQLEVKR----SGLTKELV 610
Cdd:TIGR04523   27 IANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINnsnnkiKILEQQIKDLNDKLKKNkdkiNKLNSDLS 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   611 EVREALSCAILQRDVLQTEKAEVAEALTKAEAgraQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLE 690
Cdd:TIGR04523  107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKK---NIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   691 E-EKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERqglqgslcvaeqareaLEQQILVLRSERSHLQEQLAQLSRQ 769
Cdd:TIGR04523  184 NiQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISE----------------LKKQNNQLKDNIEKKQQEINEKTTE 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   770 LSGRDQELEQALRESQRQVEALERAAREKEAMAKeraglavKLAAAEREGRTLSEEAIRLRLEKEA-----LESSLFDVQ 844
Cdd:TIGR04523  248 ISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNK-------KIKELEKQLNQLKSEISDLNNQKEQdwnkeLKSELKNQE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   845 RQLAQLEArreQLEADSQALllakETLTGELAGLRQQVT-STEEKAALDKELmTQKLVQAEreaqaSLREQRAAHEEDLQ 923
Cdd:TIGR04523  321 KKLEEIQN---QISQNNKII----SQLNEQISQLKKELTnSESENSEKQREL-EEKQNEIE-----KLKKENQSYKQEIK 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   924 RLQHEKEAAWRELQAeraqlQGQLQQEREELLARMEAEKEELSKEIAALQQERdeglllaESEKQQALSLKE--SEKTAL 1001
Cdd:TIGR04523  388 NLESQINDLESKIQN-----QEKLNQQKDEQIKKLQQEKELLEKEIERLKETI-------IKNNSEIKDLTNqdSVKELI 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1002 SEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQleeataahaqtVKELEERTGNLGRQREACMR 1081
Cdd:TIGR04523  456 IKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEE-----------KKELEEKVKDLTKKISSLKE 524

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1082 EAEELRTQLRVLEDTRDGLRRELLEaqrkgRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERI 1161
Cdd:TIGR04523  525 KIEKLESEKKEKESKISDLEDELNK-----DDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKK 599

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 568931102  1162 SLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKT 1218
Cdd:TIGR04523  600 DLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
PTZ00121 PTZ00121
MAEBL; Provisional
 1056-1816 6.03e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 6.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1056 AAHAQTVKELEERTGNLGRQREACMREAEELR--TQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEasELRRSls 1133
Cdd:PTZ00121 1103 AKKTETGKAEEARKAEEAKKKAEDARKAEEARkaEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE--DAKKA-- 1178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1134 EGAKEREALRRSnEELRSA--VKKAESERislKLANEDKEQKLALLEEARvsvakeagelraSLQEVERSRlEARRELQE 1211
Cdd:PTZ00121 1179 EAARKAEEVRKA-EELRKAedARKAEAAR---KAEEERKAEEARKAEDAK------------KAEAVKKAE-EAKKDAEE 1241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1212 LRRQMKTLDSDNGRLGREladlqGRLALGERTEKESRREALGLRQRLLKGESSLEAlkQELQGSQRKLQEQEAEFRArer 1291
Cdd:PTZ00121 1242 AKKAEEERNNEEIRKFEE-----ARMAHFARRQAAIKAEEARKADELKKAEEKKKA--DEAKKAEEKKKADEAKKKA--- 1311

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1292 gllgslEEARGAEkrlldsarslELRLEAVRAETSELGLRLSAAEGRAQGlEVELARVEAQRRVAEAQLGGLRSALRRGL 1371
Cdd:PTZ00121 1312 ------EEAKKAD----------EAKKKAEEAKKKADAAKKKAEEAKKAA-EAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1372 GLGRVSSSPAREAPAGGSGDGLSSPSPlEYSPRSQPPSPGLIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQT 1451
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKADEAKKKAE-EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA 1453

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1452 StlSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRrlsgaqAELALQEESVRRSKRECRATLDQMAVLERSLQAt 1531
Cdd:PTZ00121 1454 E--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKK------AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA- 1524

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1532 eSELRASQEKvskMKATEAKLESDKRRLKEVLDASESRsiKLELQRRALEGELQRSRLGLGDREAHaqalqdrvdsLQRQ 1611
Cdd:PTZ00121 1525 -DEAKKAEEA---KKADEAKKAEEKKKADELKKAEELK--KAEEKKKAEEAKKAEEDKNMALRKAE----------EAKK 1588

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1612 VADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLda 1691
Cdd:PTZ00121 1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE-- 1666

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1692 ARQALSEARRQSsslgeqvqtlrgELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQR 1771
Cdd:PTZ00121 1667 AKKAEEDKKKAE------------EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE 1734

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*.
gi 568931102 1772 ALAQLEAEKRDLERSAL-QFDKDRVALRKTLDKVEREKLRSHEDTL 1816
Cdd:PTZ00121 1735 AKKEAEEDKKKAEEAKKdEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 469-1359 7.52e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 7.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   469 YEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTaasaQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKE 548
Cdd:TIGR00606  212 LKQYKEKACEIRDQITSKEAQLESSREIVKSYENEL----DPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   549 LRQELEKLQAAQEElkrqhnQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQt 628
Cdd:TIGR00606  288 LELKMEKVFQGTDE------QLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQ- 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   629 EKAEVAEALTKAEAGRAQL---------ELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRliAQLEEEKVALLGR 699
Cdd:TIGR00606  361 EHIRARDSLIQSLATRLELdgfergpfsERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ--EQADEIRDEKKGL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   700 QQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQ--------QILVLRSERSHLQEQLAQLSRQLS 771
Cdd:TIGR00606  439 GRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERElskaeknsLTETLKKEVKSLQNEKADLDRKLR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   772 GRDQELEQALRE--SQRQVEALERAAREKEAMAKE----RAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQR 845
Cdd:TIGR00606  519 KLDQEMEQLNHHttTRTQMEMLTKDKMDKDEQIRKiksrHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNK 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   846 QLAQLEARREQLEADSQALllaKETLTGELAGLRQQVTSTEEKAALDKelmTQKLVQAEREAQASLREQRAAHEEDLQRL 925
Cdd:TIGR00606  599 ELASLEQNKNHINNELESK---EEQLSSYEDKLFDVCGSQDEESDLER---LKEEIEKSSKQRAMLAGATAVYSQFITQL 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   926 QHEKEAAW----RELQAErAQLQgQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESeKQQALSLKESEKTAL 1001
Cdd:TIGR00606  673 TDENQSCCpvcqRVFQTE-AELQ-EFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG-RQSIIDLKEKEIPEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1002 SEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALT--SELRDLRAQLEEATAAHAQTVKELEERTGNLGRQreac 1079
Cdd:TIGR00606  750 RNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQ---- 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1080 mreaeELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASEL---RRSLSEGAKEREALRRSNEELRSAVKka 1156
Cdd:TIGR00606  826 -----QVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELkseKLQIGTNLQRRQQFEEQLVELSTEVQ-- 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1157 eseriSLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEverSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGR 1236
Cdd:TIGR00606  899 -----SLIREIKDAKEQDSPLETFLEKDQQEKEELISSKET---SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDD 970

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1237 LALGERTEKESRREALG-LRQRLLKGESSLEALKQELQGS-QRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSL 1314
Cdd:TIGR00606  971 YLKQKETELNTVNAQLEeCEKHQEKINEDMRLMRQDIDTQkIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVL 1050

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 568931102  1315 ELRLE--AVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQ 1359
Cdd:TIGR00606 1051 QMKQEhqKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFR 1097
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 446-998 1.15e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.82  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   446 STLTLIHSALHKRQLQVQDMRGRYEASQEL--LGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRS 523
Cdd:TIGR00618  318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLqtLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQS 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   524 ANELLSREKgNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRS 603
Cdd:TIGR00618  398 LCKELDILQ-REQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQ 476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   604 GLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSltklraeeaslRDSLSKMSALNESLAQDKLELN 683
Cdd:TIGR00618  477 TKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNP-----------GPLTRRMQRGEQTYAQLETSEE 545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   684 RLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQL 763
Cdd:TIGR00618  546 DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQ 625

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   764 AQLSRQLSGRDQELEQALRESQRQVEALERAA-REKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFD 842
Cdd:TIGR00618  626 DLQDVRLHLQQCSQELALKLTALHALQLTLTQeRVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTL 705

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   843 VQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAalDKELMTQKLVQAEREAQASLREQRAAHEEDL 922
Cdd:TIGR00618  706 LRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA--RTVLKARTEAHFNNNEEVTAALQTGAELSHL 783

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102   923 QRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEK 998
Cdd:TIGR00618  784 AAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSK 859
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
911-1369 1.20e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  911 LREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDE---------GLL 981
Cdd:COG4913   260 LAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEleaqirgngGDR 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  982 LAESEKQqaLSLKESEKTALSEKLMGTRHSLAAISL-------EMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEA 1054
Cdd:COG4913   340 LEQLERE--IERLERELEERERRRARLEALLAALGLplpasaeEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1055 TAAHAQTVKELEErtgnLGRQREACMREAEELRTQL-RVLEDTRDGLR--RELLEAQRKGRDSQDSSE------------ 1119
Cdd:COG4913   418 RRELRELEAEIAS----LERRKSNIPARLLALRDALaEALGLDEAELPfvGELIEVRPEEERWRGAIErvlggfaltllv 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1120 --AHRQEASELRRSLSEGAK---EREALRRSNEELRSAVKKAESERISLK--------------------------LANE 1168
Cdd:COG4913   494 ppEHYAAALRWVNRLHLRGRlvyERVRTGLPDPERPRLDPDSLAGKLDFKphpfrawleaelgrrfdyvcvdspeeLRRH 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1169 DK---------------------------------EQKLALLEEARVSVAKEAGELRASLQEV--ERSRLEARRELQELR 1213
Cdd:COG4913   574 PRaitragqvkgngtrhekddrrrirsryvlgfdnRAKLAALEAELAELEEELAEAEERLEALeaELDALQERREALQRL 653

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1214 RQMKTLDSDNGRLGRELADLQGRLAlgertekesrrealglrqRLLKGESSLEALKQELQGSQRKLQEQEAEFRAReRGL 1293
Cdd:COG4913   654 AEYSWDEIDVASAEREIAELEAELE------------------RLDASSDDLAALEEQLEELEAELEELEEELDEL-KGE 714

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568931102 1294 LGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGL--RLSAAEGRAQGLEVElARVEAQRRVAEAQLGGLRSALRR 1369
Cdd:COG4913   715 IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLeeRFAAALGDAVERELR-ENLEERIDALRARLNRAEEELER 791
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-589 1.42e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    2 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAvRLETGELEAQEpRGLVRQSVELRRQLQEEQS 81
Cdd:COG1196   274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL-EEELAELEEEL-EELEEELEELEEELEEAEE 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   82 SYRRKLQAYQEGQQRQAQLVQRLQAKILQYKkqcsELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEEEQQRSASLA 161
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELE----ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  162 QVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQVMGLRRQASEV 241
Cdd:COG1196   428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  242 KMGTERDLLqlggelvrtsrAVQELGLGLSASLHRAESKAEAALEkqkllqAQLEEQLQAKLLREKDLAQLQVQsdLDKA 321
Cdd:COG1196   508 EGVKAALLL-----------AGLRGLAGAVAVLIGVEAAYEAALE------AALAAALQNIVVEDDEVAAAAIE--YLKA 568

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  322 DLSARVTELALSVEH---LQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQL 398
Cdd:COG1196   569 AKAGRATFLPLDKIRaraALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  399 SSSERTADTSDGSLRGFSGQRtptpprhspgrgrsprrglspacsdssTLTLIHSALHKRQLQVQDMRGRYEASQELLGS 478
Cdd:COG1196   649 VTLEGEGGSAGGSLTGGSRRE---------------------------LLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  479 VRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKL-- 556
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgp 781

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 568931102  557 --QAAQEELKRQHNQLE--DAQEDSVQEgarARRELE 589
Cdd:COG1196   782 vnLLAIEEYEELEERYDflSEQREDLEE---ARETLE 815
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
775-1210 1.61e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 1.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  775 QELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLS--EEAIRLRLEKEALESSLFDVQRQLAQLEA 852
Cdd:COG4717    74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEklLQLLPLYQELEALEAELAELPERLEELEE 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  853 R---REQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEK 929
Cdd:COG4717   154 RleeLRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  930 EAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKE---------------IAALQQERDEGLLLAESEKQQALSLK 994
Cdd:COG4717   234 NELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLIltiagvlflvlgllaLLFLLLAREKASLGKEAEELQALPAL 313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  995 ESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERtgnlgR 1074
Cdd:COG4717   314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEEL-----R 388

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1075 QREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGrdsqdSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVK 1154
Cdd:COG4717   389 AALEQAEEYQELKEELEELEEQLEELLGELEELLEAL-----DEEELEEELEELEEELEELEEELEELREELAELEAELE 463

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102 1155 KAESERislklANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQ 1210
Cdd:COG4717   464 QLEEDG-----ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 479-1094 1.81e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 1.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   479 VRKQLSDSEGERRGLEEQLQRLRDqtaasaqaqeDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQA 558
Cdd:TIGR00618  185 EFAKKKSLHGKAELLTLRSQLLTL----------CTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   559 AQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALT 638
Cdd:TIGR00618  255 QLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHV 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   639 KAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRlIAQLEEEKVALLGRQQQAEHATTMAVEKQELLE 718
Cdd:TIGR00618  335 KQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQH-IHTLQQQKTTLTQKLQSLCKELDILQREQATID 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   719 QLRLEQEVERQGL-------QGSLCVAEQAREALEQQILVLRSERSHLQE---QLAQLSRQLSGRDQELEQALRESQRQV 788
Cdd:TIGR00618  414 TRTSAFRDLQGQLahakkqqELQQRYAELCAAAITCTAQCEKLEKIHLQEsaqSLKEREQQLQTKEQIHLQETRKKAVVL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   789 EALERAAREKEAMAKERAGLAVKLAAAEREGRT------LSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQ 862
Cdd:TIGR00618  494 ARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLtrrmqrGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFS 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   863 ALLLAKETLTGELAGLRQQVTsteekaaldkelMTQKLVQAEREAQASLREQRAAHEEDLQRLQH--EKEAAWRELQAER 940
Cdd:TIGR00618  574 ILTQCDNRSKEDIPNLQNITV------------RLQDLTEKLSEAEDMLACEQHALLRKLQPEQDlqDVRLHLQQCSQEL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   941 AQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEME 1020
Cdd:TIGR00618  642 ALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFN 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1021 RQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHA--------------QTVKELEERTGNLGRQReacmREAEEL 1086
Cdd:TIGR00618  722 EIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTeahfnnneevtaalQTGAELSHLAAEIQFFN----RLREED 797


                   ....*...
gi 568931102  1087 RTQLRVLE 1094
Cdd:TIGR00618  798 THLLKTLE 805
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 922-1226 1.99e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.82  E-value: 1.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   922 LQRLQHEKEAAWRELQAERAQL-QGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTA 1000
Cdd:pfam17380  275 LHIVQHQKAVSERQQQEKFEKMeQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIR 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1001 LSE-KLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTlnaltselRDLRAQLEEATAAHAQTvKELEERTGNLGRQREAC 1079
Cdd:pfam17380  355 QEErKRELERIRQEEIAMEISRMRELERLQMERQQKN--------ERVRQELEAARKVKILE-EERQRKIQQQKVEMEQI 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1080 MREAEELRT-QLRVLEDTRDglrRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAES 1158
Cdd:pfam17380  426 RAEQEEARQrEVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELE 502

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102  1159 ERISLKLANEDKEQKLAL-LEEARVSVAKEAGELRASLQEVERSRLEARRELQElrrQMKTLDSDNGRL 1226
Cdd:pfam17380  503 ERKQAMIEEERKRKLLEKeMEERQKAIYEEERRREAEEERRKQQEMEERRRIQE---QMRKATEERSRL 568
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 489-1251 2.12e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.03  E-value: 2.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  489 ERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQEL---EKLQAAQEELKR 565
Cdd:COG3096   279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALrqqEKIERYQEDLEE 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  566 QHNQLEDAQEdsVQEGARARRELERSHRQLEQLEVKRsgLTKELVEVREALscailqrDVLQTEKAEVAEALTKAEAGRA 645
Cdd:COG3096   359 LTERLEEQEE--VVEEAAEQLAEAEARLEAAEEEVDS--LKSQLADYQQAL-------DVQQTRAIQYQQAVQALEKARA 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  646 QLELS----------LTKLRAEEASLRDSL----SKMSALNESLAQ--DKLELNRLIA------QLEEEKVALLGR---- 699
Cdd:COG3096   428 LCGLPdltpenaedyLAAFRAKEQQATEEVleleQKLSVADAARRQfeKAYELVCKIAgeversQAWQTARELLRRyrsq 507

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  700 QQQAEHATTMAVEKQELLEQLRLEQEVERQ--GLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQEL 777
Cdd:COG3096   508 QALAQRLQQLRAQLAELEQRLRQQQNAERLleEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  778 EQ--ALRESQRQVEALERAAREKEAMAKERAGLAVKLAAA---------EREgRTLSEEAIRLRLEKEALESSLfdvqRQ 846
Cdd:COG3096   588 EQlrARIKELAARAPAWLAAQDALERLREQSGEALADSQEvtaamqqllERE-REATVERDELAARKQALESQI----ER 662

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  847 LAQLEArreqleADSQALLLAKETLTGEL--------------------AGLRQQVTSTEEKAALDK----ELMTQKLVQ 902
Cdd:COG3096   663 LSQPGG------AEDPRLLALAERLGGVLlseiyddvtledapyfsalyGPARHAIVVPDLSAVKEQlaglEDCPEDLYL 736

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  903 AEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQlqQEREELLARMEAEKEELSKEIAALQQERDEGLLL 982
Cdd:COG3096   737 IEGDPDSFDDSVFDAEELEDAVVVKLSDRQWRYSRFPEVPLFGR--AAREKRLEELRAERDELAEQYAKASFDVQKLQRL 814

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  983 AESEKQ---QALSL-----KESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQdRNTLNALTSE----------- 1043
Cdd:COG3096   815 HQAFSQfvgGHLAVafapdPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQ-LQLLNKLLPQanlladetlad 893

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1044 -LRDLRAQLEEATAA------HAQTVKELEERTGNLGRQREacmrEAEELRTQLRVLEDTRDGLRRELLE----AQRKGR 1112
Cdd:COG3096   894 rLEELREELDAAQEAqafiqqHGKALAQLEPLVAVLQSDPE----QFEQLQADYLQAKEQQRRLKQQIFAlsevVQRRPH 969

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1113 DSQDSSEAHRQEASELRRSLSEGAKERE-ALRRSNEELRSAVKKAES---ERISLKLANEDKEQKLALLEEARvsvakEA 1188
Cdd:COG3096   970 FSYEDAVGLLGENSDLNEKLRARLEQAEeARREAREQLRQAQAQYSQynqVLASLKSSRDAKQQTLQELEQEL-----EE 1044

                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102 1189 GELRASLQEVERSRLEARR---ELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREA 1251
Cdd:COG3096  1045 LGVQADAEAEERARIRRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQV 1110
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
841-1371 2.40e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  841 FDVQRQLAQLEARREQLEADSQALLLAKETLT--GELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAH 918
Cdd:COG4913   221 PDTFEAADALVEHFDDLERAHEALEDAREQIEllEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEEL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  919 EEDLQRLQHEKEaawrELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQAlslkesek 998
Cdd:COG4913   301 RAELARLEAELE----RLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALL-------- 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  999 TALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATaahaQTVKELEERTGNLGRqrea 1078
Cdd:COG4913   369 AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE----AEIASLERRKSNIPA---- 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1079 cmrEAEELRTQL-RVLEDTRDGLR--RELLEAQRKGRDSQDSSE-AHRQEASELrrsLSEGAKEREALRRSNEELRSAVK 1154
Cdd:COG4913   441 ---RLLALRDALaEALGLDEAELPfvGELIEVRPEEERWRGAIErVLGGFALTL---LVPPEHYAAALRWVNRLHLRGRL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1155 KAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASL-QEVERSRLEARRELQELRRQMkTLD---SDNGRLgREL 1230
Cdd:COG4913   515 VYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELgRRFDYVCVDSPEELRRHPRAI-TRAgqvKGNGTR-HEK 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1231 AD---LQGRLALGERTE---KESRREALGLRQRLLKGESSLEALKQELQGSQRKLQ--EQEAEFRARERGLLGSLEEARG 1302
Cdd:COG4913   593 DDrrrIRSRYVLGFDNRaklAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAE 672

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568931102 1303 AEKRL--LDSA----RSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGL 1371
Cdd:COG4913   673 LEAELerLDASsddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL 747
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 538-954 2.44e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 52.75  E-value: 2.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  538 SLQVTQQQAKELRQELEKLQAAQ--------EELKRQHNQLEDAQE--DSVQEGARARRELERSHRQLEQlevKRSGLTK 607
Cdd:PRK10929   17 AYAATAPDEKQITQELEQAKAAKtpaqaeivEALQSALNWLEERKGslERAKQYQQVIDNFPKLSAELRQ---QLNNERD 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  608 ELVEVREALSCAILQRDVLQTeKAEVAEaltkaEAGRAQLElsltKLRAEEASlrDSLSKmsalnesLAQDKLELNRLIA 687
Cdd:PRK10929   94 EPRSVPPNMSTDALEQEILQV-SSQLLE-----KSRQAQQE----QDRAREIS--DSLSQ-------LPQQQTEARRQLN 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  688 QLEeekvallgRQQQAEHATTMAVEKQELLEqlrLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERshLQEQLAQLS 767
Cdd:PRK10929  155 EIE--------RRLQTLGTPNTPLAQAQLTA---LQAESAALKALVDELELAQLSANNRQELARLRSEL--AKKRSQQLD 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  768 RQLsgrdqeleQALRE---SQRQVEAlERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEairlrLEKEALESSLF-DV 843
Cdd:PRK10929  222 AYL--------QALRNqlnSQRQREA-ERALESTELLAEQSGDLPKSIVAQFKINRELSQA-----LNQQAQRMDLIaSQ 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  844 QRQLAQ--LEARREQLEADSQALLLAKETLTGElaGLRQQVTSTEEKAaldkelmtqKLVQAEREaQASLREQRAAHEED 921
Cdd:PRK10929  288 QRQAASqtLQVRQALNTLREQSQWLGVSNALGE--ALRAQVARLPEMP---------KPQQLDTE-MAQLRVQRLRYEDL 355

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 568931102  922 LQRLQHEKEAAWRELQ----AERAQLQGQLQQEREEL 954
Cdd:PRK10929  356 LNKQPQLRQIRQADGQpltaEQNRILDAQLRTQRELL 392
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2-769 3.07e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 3.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102     2 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAVRLETGELEAQ--EPRGLVRQSVELRRQLQEE 79
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEiaSLERSIAEKERELEDAEER 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    80 Q-------SSYRRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEE 152
Cdd:TIGR02169  324 LakleaeiDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   153 EQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREavwrREEESFNTYFSSEHSRLLRLWRQVM 232
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE----WKLEQLAADLSKYEQELYDLKEEYD 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   233 GLRRQASEVKMGTERDLLQLG--GELVRTSRAVQELG-------LGLSASLHRAESKAEAALEkqkllqAQLEEQLQAKL 303
Cdd:TIGR02169  480 RVEKELSKLQRELAEAEAQARasEERVRGGRAVEEVLkasiqgvHGTVAQLGSVGERYATAIE------VAAGNRLNNVV 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   304 LREKDLAQLQVQsdLDKADLSARVTELALsvehlqnqnSEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRD 383
Cdd:TIGR02169  554 VEDDAVAKEAIE--LLKRRKAGRATFLPL---------NKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGD 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   384 laQAALSDTESGVQLSSSERTAdTSDGSLRGFSGQRTptpprhspGRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQ 463
Cdd:TIGR02169  623 --TLVVEDIEAARRLMGKYRMV-TLEGELFEKSGAMT--------GGSRAPRGGILFSRSEPAELQRLRERLEGLKRELS 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   464 DMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQ 543
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   544 QQAKELRQELEKLQA--AQEELKRQHNQLEDAQEDSVQEGARAR---RELERSHRQLEQLEVKRSGLTKELVEVREALSC 618
Cdd:TIGR02169  772 EDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEARLReieQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   619 AILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLG 698
Cdd:TIGR02169  852 IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE 931

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   699 RQQQAEHATTMAVEKQELL--------EQLRLEQEVERQGLQGSLCVAEQAREA-----LEQQILVLRSERSHLQEQLAQ 765
Cdd:TIGR02169  932 ELSEIEDPKGEDEEIPEEElsledvqaELQRVEEEIRALEPVNMLAIQEYEEVLkrldeLKEKRAKLEEERKAILERIEE 1011


                   ....
gi 568931102   766 LSRQ 769
Cdd:TIGR02169 1012 YEKK 1015
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
824-1223 3.31e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.08  E-value: 3.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  824 EEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQA 903
Cdd:COG4717    74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  904 EREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEgLLLA 983
Cdd:COG4717   154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQL 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  984 ESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQkrdaqsrqeqdRNTLNALTSELRDLRAQLEEATAAHAQTVK 1063
Cdd:COG4717   233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSL-----------ILTIAGVLFLVLGLLALLFLLLAREKASLG 301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1064 ELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEA--SELRRSLSE-----GA 1136
Cdd:COG4717   302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAAllaeaGV 381

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1137 KEREALRRSNEELRSAVK-KAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQ 1215
Cdd:COG4717   382 EDEEELRAALEQAEEYQElKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461


                  ....*...
gi 568931102 1216 MKTLDSDN 1223
Cdd:COG4717   462 LEQLEEDG 469
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1204-1793 3.76e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 3.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1204 EARRELQELRRQMKTLdsdngrlgRELADLQGRLAlgERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQE 1283
Cdd:COG4913   239 RAHEALEDAREQIELL--------EPIRELAERYA--AARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLE 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1284 AEFRARERGLLGSLEEARGAEKRLLDSARSlelRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGL 1363
Cdd:COG4913   309 AELERLEARLDALREELDELEAQIRGNGGD---RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1364 RSALRRGLGLGRVSSSPAREAPAggsgdglsspspleysprsqppspgliaspappdldpeAVRDALRDFLQELRSAQRE 1443
Cdd:COG4913   386 RAEAAALLEALEEELEALEEALA--------------------------------------EAEAALRDLRRELRELEAE 427

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1444 RDELKVQTSTLSQQLVEMEAE-RDHAASRAKQLQKA-----VAESEEAWRSADRRLSGAQAELALQEEsvrrskrecrat 1517
Cdd:COG4913   428 IASLERRKSNIPARLLALRDAlAEALGLDEAELPFVgelieVRPEEERWRGAIERVLGGFALTLLVPP------------ 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1518 lDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASES---RSIKLELQRRAL------EGELQRSR 1588
Cdd:COG4913   496 -EHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHpfrAWLEAELGRRFDyvcvdsPEELRRHP 574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1589 LGL-------GDREAHAQALQDRVDSL-------QRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDAL 1654
Cdd:COG4913   575 RAItragqvkGNGTRHEKDDRRRIRSRyvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLA 654

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1655 TQSSASL--SSTQDKNLHLQKALSTCE---HDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEG 1729
Cdd:COG4913   655 EYSWDEIdvASAEREIAELEAELERLDassDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568931102 1730 QLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERL-GSLQRALAQLEAEKRDLERSALQFDKD 1793
Cdd:COG4913   735 RLEAAEDLARLELRALLEERFAAALGDAVERELRENLeERIDALRARLNRAEEELERAMRAFNRE 799
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 539-1336 4.70e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.71  E-value: 4.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   539 LQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSC 618
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   619 AILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKlelnrliaQLEEEKVALLG 698
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKER--------KLLEERISEFT 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   699 RQQQAEHattmavEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELE 778
Cdd:pfam01576  166 SNLAEEE------EKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   779 QALRESQRQVEALERAAREKEAMAKERAGLAVKLA------AAEREGRTLSEEAIR-LRLEKEALESSLFDVQRQLAQLE 851
Cdd:pfam01576  240 KKEEELQAALARLEEETAQKNNALKKIRELEAQISelqedlESERAARNKAEKQRRdLGEELEALKTELEDTLDTTAAQQ 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   852 ARREQLEADSQALllaKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEReAQASLREQRAAHEEDLQRLQHEK-- 929
Cdd:pfam01576  320 ELRSKREQEVTEL---KKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKR-NKANLEKAKQALESENAELQAELrt 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   930 -EAAWRELQAERAQLQGQLQ-------------QEREELLARMEAEKE--------------ELSKEIAALQQERDEGLL 981
Cdd:pfam01576  396 lQQAKQDSEHKRKKLEGQLQelqarlseserqrAELAEKLSKLQSELEsvssllneaegkniKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   982 LAESEKQQALSLK------ESEKTALSEKL---MGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNA-------LTSELR 1045
Cdd:pfam01576  476 LLQEETRQKLNLStrlrqlEDERNSLQEQLeeeEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAleegkkrLQRELE 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1046 DLRAQLEEATAAHAQTVK-------ELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSS 1118
Cdd:pfam01576  556 ALTQQLEEKAAAYDKLEKtknrlqqELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKE 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1119 eahrQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEV 1198
Cdd:pfam01576  636 ----TRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQAT 711

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1199 ERSRLEARRELQELR----RQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQG 1274
Cdd:pfam01576  712 EDAKLRLEVNMQALKaqfeRDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANK 791

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568931102  1275 SQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAE 1336
Cdd:pfam01576  792 GREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASE 853
PRK11281 PRK11281
mechanosensitive channel MscK;
504-794 5.53e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.84  E-value: 5.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  504 TAASAQAQEDAQREaQRLRSANELLSreKGNLTHSLQV---TQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQE 580
Cdd:PRK11281   37 TEADVQAQLDALNK-QKLLEAEDKLV--QQDLEQTLALldkIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEE 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  581 garARRELERshRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEAS 660
Cdd:PRK11281  114 ---TRETLST--LSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKA 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  661 LRDSLSKM-----SALNESLAQDKLEL---NRLIAQLEEEKVALLGRQQQAEHATTmavEKQELLEQLRLEQEverqglq 732
Cdd:PRK11281  189 LRPSQRVLlqaeqALLNAQNDLQRKSLegnTQLQDLLQKQRDYLTARIQRLEHQLQ---LLQEAINSKRLTLS------- 258

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568931102  733 gslcvAEQAREALEQQILVLRSERSHLQEQLA---QLSRQLSGRDQELEQALRESQRQVEALERA 794
Cdd:PRK11281  259 -----EKTVQEAQSQDEAARIQANPLVAQELEinlQLSQRLLKATEKLNTLTQQNLRVKNWLDRL 318
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1687-1917 7.07e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 7.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1687 ERLDAARQALSEARRQSSSLgEQVQTLRGELASLELQRGDAEgqlqqlqqalrqrqegEAMALRSVQKLQEERRLLQERL 1766
Cdd:COG4913   235 DDLERAHEALEDAREQIELL-EPIRELAERYAAARERLAELE----------------YLRAALRLWFAQRRLELLEAEL 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1767 GSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRshedtlRLNAERGRLDRTLTGAELDLAEAQQQIQHL 1846
Cdd:COG4913   298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLE------QLEREIERLERELEERERRRARLEALLAAL 371

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568931102 1847 EAQVDVALEGNHNpVQPEAGEQQLELQQEVERLRSAQVQTE---RTLEARERAHRQRVSGLEEQVSTLKAQLHQ 1917
Cdd:COG4913   372 GLPLPASAEEFAA-LRAEAAALLEALEEELEALEEALAEAEaalRDLRRELRELEAEIASLERRKSNIPARLLA 444
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 886-1094 7.45e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  886 EEKAALDKELM-TQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQgQLQQEREELLARMEAEKEE 964
Cdd:COG4942    27 AELEQLQQEIAeLEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELEKEIAELRAELEAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  965 LSKEIAALQQ--ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDaqsrQEQDRNTLNALTS 1042
Cdd:COG4942   106 LAELLRALYRlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE----LEAERAELEALLA 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 568931102 1043 ELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLE 1094
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 749-999 7.61e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 51.08  E-value: 7.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  749 ILVLRSERSHLQEQLAQLS----RQLSGRDQ--ELEQALRESQRQVEALE--RAAREKEAMAKERAGLAVKLaaaeregr 820
Cdd:PRK05771   11 IVTLKSYKDEVLEALHELGvvhiEDLKEELSneRLRKLRSLLTKLSEALDklRSYLPKLNPLREEKKKVSVK-------- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  821 tlSEEAIRLRLEKEA--LESSLFDVQRQLAQLEARREQLEADSQAL------------LLAKETLTGELAGL------RQ 880
Cdd:PRK05771   83 --SLEELIKDVEEELekIEKEIKELEEEISELENEIKELEQEIERLepwgnfdldlslLLGFKYVSVFVGTVpedkleEL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  881 QVTSTEEKAALDKELMTQK--LVQAEREAQASLREQRAAHEEDLQRLQHEKEAAwrelqaeraqlqgQLQQEREELLARM 958
Cdd:PRK05771  161 KLESDVENVEYISTDKGYVyvVVVVLKELSDEVEEELKKLGFERLELEEEGTPS-------------ELIREIKEELEEI 227

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 568931102  959 EAEKEELSKEIAALQQERDE------GLLLAESEKQQALS-LKESEKT 999
Cdd:PRK05771  228 EKERESLLEELKELAKKYLEellalyEYLEIELERAEALSkFLKTDKT 275
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1422-1899 8.09e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.11  E-value: 8.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1422 DPEAVRDALRDFLQELRSAQRERDELKvQTSTLSQQLVEMEAERDhaASRAKQLQKAVAESEEAWRSADRRLSGAQAELA 1501
Cdd:COG3096   233 DMEAALRENRMTLEAIRVTQSDRDLFK-HLITEATNYVAADYMRH--ANERRELSERALELRRELFGARRQLAEEQYRLV 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1502 lqeesvrrskrecrATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASEsrsiKLELQRRALE 1581
Cdd:COG3096   310 --------------EMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKIERYQEDLEELTE----RLEEQEEVVE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1582 gELQRSRLglgDREAHAQALQDRVDSLQRQVAD-------SEVKAGTLQLTVERLSGA----------LAKVEESEGNLR 1644
Cdd:COG3096   372 -EAAEQLA---EAEARLEAAEEEVDSLKSQLADyqqaldvQQTRAIQYQQAVQALEKAralcglpdltPENAEDYLAAFR 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1645 SKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEH--DRQVLQERLDAARQALSEARRQSSsLGEQVQTLRGELASLEl 1722
Cdd:COG3096   448 AKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiaGEVERSQAWQTARELLRRYRSQQA-LAQRLQQLRAQLAELE- 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1723 qrgdaegqlQQLQQALRQRQEGEAMALRSVQKLQEERrllqerlgSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLD 1802
Cdd:COG3096   526 ---------QRLRQQQNAERLLEEFCQRIGQQLDAAE--------ELEELLAELEAQLEELEEQAAEAVEQRSELRQQLE 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1803 KVEREKlrshedtlrlnaergrldRTLTGAELDLAEAQQQIQHLEAQVDVALEgnhnpvqpEAGEQQLELQQEVERLRSA 1882
Cdd:COG3096   589 QLRARI------------------KELAARAPAWLAAQDALERLREQSGEALA--------DSQEVTAAMQQLLEREREA 642

                         490
                  ....*....|....*..
gi 568931102 1883 QVQTERTLEARERAHRQ 1899
Cdd:COG3096   643 TVERDELAARKQALESQ 659
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 775-1273 8.76e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.89  E-value: 8.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   775 QELEQALRESQRQVEALERAAREKEAMAKERA--------GLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQ 846
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsviDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   847 LAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTeekaaldkelmtqkLVQAEREAQASLREQRAAHEEDLQRLQ 926
Cdd:pfam15921  154 LEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSI--------------LVDFEEASGKKIYEHDSMSTMHFRSLG 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   927 HEKEAAWRELQAERAQLQGQLQQEREELlarmEAEKEELSKEIAALQQERDEGLllaesekQQALSLKESEKTALSEKLM 1006
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQL----EALKSESQNKIELLLQQHQDRI-------EQLISEHEVEITGLTEKAS 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1007 GTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEER-------TGNLGRQREAC 1079
Cdd:pfam15921  289 SARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQlvlanseLTEARTERDQF 368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1080 MREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVK-KAES 1158
Cdd:pfam15921  369 SQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMER 448

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1159 ERISLKLANEDKEQKLAL---LEEARVSVAKEAGELRA---SLQEVERSRLEARRELQELRRQMKTLDSDNGRLgRELAD 1232
Cdd:pfam15921  449 QMAAIQGKNESLEKVSSLtaqLESTKEMLRKVVEELTAkkmTLESSERTVSDLTASLQEKERAIEATNAEITKL-RSRVD 527

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 568931102  1233 LQGRLALGERTEKESRR----EALGLRQRLLKGESSLEALKQELQ 1273
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQIE 572
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 869-1217 1.14e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.51  E-value: 1.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   869 ETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAawrelQAERAQLQGQLQ 948
Cdd:pfam17380  269 EFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDR-----QAAIYAEQERMA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   949 QEREELLARMeaEKEELSKEIAALQQERdeglLLAESEKQQALSLKESEKTALSEKLmgtRHSLAAIS----LEMERQKR 1024
Cdd:pfam17380  344 MERERELERI--RQEERKRELERIRQEE----IAMEISRMRELERLQMERQQKNERV---RQELEAARkvkiLEEERQRK 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1025 DAQSRQEQDRntlnaltselrdLRAQLEEATAAHAQTVKelEERTGNLGRQREacmrEAEELRTQLRVLEDTRDGLRREL 1104
Cdd:pfam17380  415 IQQQKVEMEQ------------IRAEQEEARQREVRRLE--EERAREMERVRL----EEQERQQQVERLRQQEEERKRKK 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1105 LEAQRKGRDSQDSSEAHR----QEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERIslklANEDKEQKLALLEEA 1180
Cdd:pfam17380  477 LELEKEKRDRKRAEEQRRkileKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRRE----AEEERRKQQEMEERR 552

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 568931102  1181 RVsvakeagELRASLQEVERSRLEARRELQELRRQMK 1217
Cdd:pfam17380  553 RI-------QEQMRKATEERSRLEAMEREREMMRQIV 582
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 469-1027 1.17e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.49  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   469 YEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSRekgnlthSLQVTQQQAKE 548
Cdd:pfam05483  221 HEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDE-------NLKELIEKKDH 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   549 LRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALScAILQRDVLQT 628
Cdd:pfam05483  294 LTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLE-ELLRTEQQRL 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   629 EKAEVAEALTKAEAGRAQLELS-LTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQL---EEEKVALLGRQQQAE 704
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELkgkEQELIFLLQAREKEI 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   705 H-----ATTMAVEKQELLEQLR-LEQEVERQGLQGSLCVAEQAREALEQQILVlrSERSHLQEQLAQLSRQLSGRDQELE 778
Cdd:pfam05483  453 HdleiqLTAIKTSEEHYLKEVEdLKTELEKEKLKNIELTAHCDKLLLENKELT--QEASDMTLELKKHQEDIINCKKQEE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   779 QALRESQRQVEALERAAREKEAMAKE----RAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARR 854
Cdd:pfam05483  531 RMLKQIENLEEKEMNLRDELESVREEfiqkGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNI 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   855 EQLEADSQALLLAKETLTGELAGLRQQVTSTEekaaLDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWR 934
Cdd:pfam05483  611 EELHQENKALKKKGSAENKQLNAYEIKVNKLE----LELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADE 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   935 ELQAERaQLQGQLQQEREELLARMEAEKEELSKEIaalqQERDEGLLLAESEKQQALSLKESEKTALSE---KLMGTRHS 1011
Cdd:pfam05483  687 AVKLQK-EIDKRCQHKIAEMVALMEKHKHQYDKII----EERDSELGLYKNKEQEQSSAKAALEIELSNikaELLSLKKQ 761

                          570
                   ....*....|....*.
gi 568931102  1012 LAAISLEMERQKRDAQ 1027
Cdd:pfam05483  762 LEIEKEEKEKLKMEAK 777
mukB PRK04863
chromosome partition protein MukB;
742-1181 1.32e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 50.34  E-value: 1.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  742 REALEQQILVLRSERSHLQEQLAQLSRQlsgrdqeleqaLRESQRQVEALERAAREKEAMAkeragLAVKLAAAEREGRT 821
Cdd:PRK04863  781 RAAREKRIEQLRAEREELAERYATLSFD-----------VQKLQRLHQAFSRFIGSHLAVA-----FEADPEAELRQLNR 844

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  822 LSEEAIRlrlEKEALESSLFDVQRQLAQLEARREQLEA-DSQALLLAKETLTGELAGLRQQVTSTEEkAALDKELMTQKL 900
Cdd:PRK04863  845 RRVELER---ALADHESQEQQQRSQLEQAKEGLSALNRlLPRLNLLADETLADRVEEIREQLDEAEE-AKRFVQQHGNAL 920

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  901 VQAEREAqASLREQraahEEDLQRLQHEKEAAWRELQAERAQLQGQlqqerEELLARMEAEKEELSKEIAALQQERDEGL 980
Cdd:PRK04863  921 AQLEPIV-SVLQSD----PEQFEQLKQDYQQAQQTQRDAKQQAFAL-----TEVVQRRAHFSYEDAAEMLAKNSDLNEKL 990

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  981 llaesekQQALSLKESEKTALSEKLMGTRHSLAaislEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQ 1060
Cdd:PRK04863  991 -------RQRLEQAEQERTRAREQLRQAQAQLA----QYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERAR 1059

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1061 TVKelEERTGNLGRQREACmreaEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKERE 1140
Cdd:PRK04863 1060 ARR--DELHARLSANRSRR----NQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVERR 1133

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 568931102 1141 ALRR-----SNEELRSAVKKAESeriSLKLA---NEDKEQKLALLEEAR 1181
Cdd:PRK04863 1134 LHRRelaylSADELRSMSDKALG---ALRLAvadNEHLRDVLRLSEDPK 1179
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 477-974 1.34e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.34  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  477 GSVRKQLSDSEG----ERRGLEE--QLQRLRDQ-----TAASAQAQEDAQREAQRLRSANELLSREKGNLTHS---LQVT 542
Cdd:COG3096   225 SGVRKAFQDMEAalreNRMTLEAirVTQSDRDLfkhliTEATNYVAADYMRHANERRELSERALELRRELFGArrqLAEE 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  543 QQQAKELRQELEKLQAAQEELKRQHNQLEDaQEDSVQEGARARRELERSHRQLEQLEVK-------RSGLTKELVEVREA 615
Cdd:COG3096   305 QYRLVEMARELEELSARESDLEQDYQAASD-HLNLVQTALRQQEKIERYQEDLEELTERleeqeevVEEAAEQLAEAEAR 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  616 LSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEAslrdsLSKMSALNESLAQDKLElnRLIAQLEEEKVA 695
Cdd:COG3096   384 LEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARA-----LCGLPDLTPENAEDYLA--AFRAKEQQATEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  696 LLGRQQQAEHATTMAVEKQELLEQLR-LEQEVERQGlqgslcVAEQAREALEQQilvlrSERSHLQEQLAQLSRQLSgrd 774
Cdd:COG3096   457 VLELEQKLSVADAARRQFEKAYELVCkIAGEVERSQ------AWQTARELLRRY-----RSQQALAQRLQQLRAQLA--- 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  775 qELEQALRESQRQVEALERAARekeamakeraGLAVKLAAAEregrTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARR 854
Cdd:COG3096   523 -ELEQRLRQQQNAERLLEEFCQ----------RIGQQLDAAE----ELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  855 EQLEADSQALllaketltgelaglrqqvtsteekaaldkelmtQKLVQAEREAQASLreqraaheedlQRLQHEKEAAWR 934
Cdd:COG3096   588 EQLRARIKEL---------------------------------AARAPAWLAAQDAL-----------ERLREQSGEALA 623

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 568931102  935 ELQAERAQLQGQLQQEREELLARME--AEKEELSKEIAALQQ 974
Cdd:COG3096   624 DSQEVTAAMQQLLEREREATVERDElaARKQALESQIERLSQ 665
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
4-186 1.36e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 1.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    4 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAVRLETGELEAQEPRGLVRQSVELRRQLQEEQSSY 83
Cdd:COG3206   207 LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARY 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   84 RRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEEEQQRSASLAQV 163
Cdd:COG3206   287 TPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366

                         170       180
                  ....*....|....*....|...
gi 568931102  164 NAMLREQLDQANLANQALSEDIR 186
Cdd:COG3206   367 YESLLQRLEEARLAEALTVGNVR 389
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 8-567 1.43e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.50  E-value: 1.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102     8 QEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAVRLETGEL-EAQEPRGLVRQ-SVELRRQLQEEQSSYRR 85
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELtEARTERDQFSQeSGNLDDQLQKLLADLHK 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    86 KLQAYQEGQQRQAQLVQR----------LQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSAllrLEEEQQ 155
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRdtgnsitidhLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNES---LEKVSS 465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   156 RSASLAQVNAMLREQLDQANLANQALSEDIRKVtSDWTRSCKELEqreavwrREEESFNTYFSSEHSRLLRLWRQVMGLR 235
Cdd:pfam15921  466 LTAQLESTKEMLRKVVEELTAKKMTLESSERTV-SDLTASLQEKE-------RAIEATNAEITKLRSRVDLKLQELQHLK 537

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   236 RQASEVK-MGTERDLLQLggELVRTSRAVQELGLGLSASLHRAESKAEAALEKQkLLQAQLEEQLQAKLLREKDLAQLQV 314
Cdd:pfam15921  538 NEGDHLRnVQTECEALKL--QMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQ-VEKAQLEKEINDRRLELQEFKILKD 614

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   315 QSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLD--TEDGEGLQQTLRDLAQAALSDT 392
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNslSEDYEVLKRNFRNKSEEMETTT 694

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   393 ES-GVQLSSSERTADTSDGSLRGFSGqrtptpprhSPGRGRSPRRGLspacsdsstltlihsalhkrQLQVQDMRGRYEA 471
Cdd:pfam15921  695 NKlKMQLKSAQSELEQTRNTLKSMEG---------SDGHAMKVAMGM--------------------QKQITAKRGQIDA 745

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   472 SQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQ 551
Cdd:pfam15921  746 LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825

                          570
                   ....*....|....*.
gi 568931102   552 ELEKLQAAQEELKRQH 567
Cdd:pfam15921  826 IIQRQEQESVRLKLQH 841
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1671-1916 1.57e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1671 LQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALR 1750
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1751 SVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVE--REKLRSHEDTLR-----LNAERG 1823
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEeqLETLRSKVAQLElqiasLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1824 RLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLrsaqVQTERTLEARERAHRQRVSG 1903
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERL----EEALEELREELEEAEQALDA 479

                          250
                   ....*....|...
gi 568931102  1904 LEEQVSTLKAQLH 1916
Cdd:TIGR02168  480 AERELAQLQARLD 492
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 739-1375 1.69e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 1.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   739 EQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAERE 818
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   819 GRTLSEEAIRLRLEKEALESSLFDVQ-RQLAQLEARREQLEADSQALLLAKETL-TGELAGLRQQVTSTEEKAALDKELM 896
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEeKEKKLQEEELKLLAKEEEELKSELLKLeRRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   897 TQKLVQAEREAQ---ASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQ 973
Cdd:pfam02463  332 KEKEEIEELEKElkeLEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   974 QERDEGLLLAESEKQQALSLKESEKTALSEKLmgTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEE 1053
Cdd:pfam02463  412 ELARQLEDLLKEEKKEELEILEEEEESIELKQ--GKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1054 ATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLS 1133
Cdd:pfam02463  490 LSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRA 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1134 EGAKEREALRRSNE-ELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRE--LQ 1210
Cdd:pfam02463  570 LTELPLGARKLRLLiPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKEsgLR 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1211 ELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGL----RQRLLKGESSLEALKQELQGSQRKLQEQEAEF 1286
Cdd:pfam02463  650 KGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEilrrQLEIKKKEQREKEELKKLKLEAEELLADRVQE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1287 RARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSA 1366
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809


                   ....*....
gi 568931102  1367 LRRGLGLGR 1375
Cdd:pfam02463  810 LKEEAELLE 818
PTZ00121 PTZ00121
MAEBL; Provisional
 1424-1924 1.96e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1424 EAVRDA--LRDFLQELRSAQRERDE---LKVQTSTLSQQLVEMEAERDHAASRAKQLQKA--VAESEEAWRSADRRLS-- 1494
Cdd:PTZ00121 1227 EAVKKAeeAKKDAEEAKKAEEERNNeeiRKFEEARMAHFARRQAAIKAEEARKADELKKAeeKKKADEAKKAEEKKKAde 1306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1495 -GAQAELALQEESVRRSKRECRATLDQMAV-LERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIK 1572
Cdd:PTZ00121 1307 aKKKAEEAKKADEAKKKAEEAKKKADAAKKkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1573 LELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSgalaKVEESEGNLRSKVQSLTD 1652
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK----KADEAKKKAEEAKKAEEA 1462

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1653 ALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQ 1732
Cdd:PTZ00121 1463 KKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA 1542

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1733 QLQQALRQRQEGEAM-ALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRS 1811
Cdd:PTZ00121 1543 EEKKKADELKKAEELkKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1812 HEdtLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQlELQQEVERLRSAQVQTERTLE 1891
Cdd:PTZ00121 1623 EE--LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE-EAKKAEEDEKKAAEALKKEAE 1699

                         490       500       510
                  ....*....|....*....|....*....|...
gi 568931102 1892 ARERAHRQRVSGLEEQVSTLKAQLHQELRRSSA 1924
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKKKAEELKKAEEENKIKA 1732
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
468-931 2.18e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 2.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  468 RYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANEL-------------LSREKGN 534
Cdd:PRK03918  232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKaeeyiklsefyeeYLDELRE 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  535 LTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQED--SVQEGARARRELERSHRQLEQLEVKRSGLTKELV-- 610
Cdd:PRK03918  312 IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRleELEERHELYEEAKAKKEELERLKKRLTGLTPEKLek 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  611 ----------EVREALSCAILQRDVLQTEKAEVAEALTKAEagRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKL 680
Cdd:PRK03918  392 eleelekakeEIEEEISKITARIGELKKEIKELKKAIEELK--KAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELK 469

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  681 ELNRLIAQLEEEKVALLGRQQQAEHATTMavekQELLEQLR-LEQEVERQGLQgSLCVAEQAREALEQQILVLRSERSHL 759
Cdd:PRK03918  470 EIEEKERKLRKELRELEKVLKKESELIKL----KELAEQLKeLEEKLKKYNLE-ELEKKAEEYEKLKEKLIKLKGEIKSL 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  760 QEQLAQLsRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKlaaaerEGRTLSEEAIRLRLEKEALESS 839
Cdd:PRK03918  545 KKELEKL-EELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLK------ELEPFYNEYLELKDAEKELERE 617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  840 LFDVQRQLAQLEARREQLEADSQALllakETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHE 919
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRL----EELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIK 693

                         490
                  ....*....|..
gi 568931102  920 EDLQRLQHEKEA 931
Cdd:PRK03918  694 KTLEKLKEELEE 705
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1468-1707 2.48e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1468 AASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKA 1547
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1548 TEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDR----EAHAQALQDRVDSLQRQVADSEVKAGTLQ 1623
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1624 LTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKalstcehDRQVLQERLDAARQALSEARRQS 1703
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ-------EAEELEALIARLEAEAAAAAERT 243


                  ....
gi 568931102 1704 SSLG 1707
Cdd:COG4942   244 PAAG 247
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 487-1237 2.67e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.40  E-value: 2.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   487 EGERRGLEEQLQRLRDQTAAS----AQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEE 562
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQAleelTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQE 416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   563 LKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEA 642
Cdd:pfam01576  417 LQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLED 496

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   643 GRAQLElslTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLrl 722
Cdd:pfam01576  497 ERNSLQ---EQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKL-- 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   723 eqeverqglqgslcvaEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAarekEAMA 802
Cdd:pfam01576  572 ----------------EKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRA----EAEA 631

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   803 KERAGLAVKLAAAEREGRTLSEEAIR----LRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGEL--- 875
Cdd:pfam01576  632 REKETRALSLARALEEALEAKEELERtnkqLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELqat 711

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   876 --AGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWR-ELQAERAQLQGQLQ---Q 949
Cdd:pfam01576  712 edAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKkKLELDLKELEAQIDaanK 791

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   950 EREEL---LARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLkESEKTALSEKLMGTRHSLAAISLEMErQKRDA 1026
Cdd:pfam01576  792 GREEAvkqLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNL-EAELLQLQEDLAASERARRQAQQERD-ELADE 869

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1027 QSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLE 1106
Cdd:pfam01576  870 IASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKE 949

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1107 AQRKGRDSQDSSEA-HRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVA 1185
Cdd:pfam01576  950 LKAKLQEMEGTVKSkFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGN 1029

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568931102  1186 KEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRL 1237
Cdd:pfam01576 1030 SRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 828-1016 2.80e-05

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 49.31  E-value: 2.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  828 RLRLEKEALESSLFDVQRQLAQLEARREQLEADsqalllaketltgelaglrQQVTSTEEKAALDKELmtqklvQAEREA 907
Cdd:COG0542   401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKE-------------------QDEASFERLAELRDEL------AELEEE 455

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  908 QASLREQRAAHEEDLQRLQHEKEAAwRELQAERAQLQGQLQQEREELLARMEAEKEELSKE-IAA---------LQQerd 977
Cdd:COG0542   456 LEALKARWEAEKELIEEIQELKEEL-EQRYGKIPELEKELAELEEELAELAPLLREEVTEEdIAEvvsrwtgipVGK--- 531

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 568931102  978 egllLAESEKQQALSLKEsektALSEKLMGTRHSLAAIS 1016
Cdd:COG0542   532 ----LLEGEREKLLNLEE----ELHERVIGQDEAVEAVA 562
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 572-831 2.92e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  572 DAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSL 651
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  652 TKLRAEEASLRDSLSKMSALNeslaqdklelnrliaqleeeKVALLGRQQQAEHATTMAvekqELLEQLRLEQEVERQGL 731
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQP--------------------PLALLLSPEDFLDAVRRL----QYLKYLAPARREQAEEL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  732 QGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVK 811
Cdd:COG4942   156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235

                         250       260
                  ....*....|....*....|
gi 568931102  812 LAAAEREGRTLSEEAIRLRL 831
Cdd:COG4942   236 AAAAAERTPAAGFAALKGKL 255
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 686-890 3.10e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  686 IAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQ 765
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  766 LSRQLSGR------------------DQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAI 827
Cdd:COG4942   102 QKEELAELlralyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568931102  828 RLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAA 890
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1131-1335 3.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 3.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1131 SLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQ 1210
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1211 ELRRQMKTLDSDNGRLGR-----------ELADLQGRLALGERTEKESRREALGLR----------QRLLKGESSLEALK 1269
Cdd:COG4942   101 AQKEELAELLRALYRLGRqpplalllspeDFLDAVRRLQYLKYLAPARREQAEELRadlaelaalrAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568931102 1270 QELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAA 1335
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 775-1282 3.84e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 3.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  775 QELEQALRESQRQVEALeRAAREKEAMAKERAGLAVKLAAAE-----REGRTLSEEAIRLRLE----KEAL---ESSLFD 842
Cdd:COG3096   232 QDMEAALRENRMTLEAI-RVTQSDRDLFKHLITEATNYVAADymrhaNERRELSERALELRRElfgaRRQLaeeQYRLVE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  843 VQRQLAQLEARREQLEADSQAlllAKETLTGELAGLRQQvtsteekaaldkelmtqklvqaereaqaslrEQRAAHEEDL 922
Cdd:COG3096   311 MARELEELSARESDLEQDYQA---ASDHLNLVQTALRQQ-------------------------------EKIERYQEDL 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  923 QRLqhekEAAWRELQAERAQLQGQlQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAeSEKQQALSLKESEKTALS 1002
Cdd:COG3096   357 EEL----TERLEEQEEVVEEAAEQ-LAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRA-IQYQQAVQALEKARALCG 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1003 eklmgtrhsLAAISLEmerqkrDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGR-QREACMR 1081
Cdd:COG3096   431 ---------LPDLTPE------NAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEvERSQAWQ 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1082 EAEELRTQLRvledtrdglrrelleaqrkgrdsqdSSEAHRQEASELRRSLSEgAKEREALRRSNEELRSAVKKAESERI 1161
Cdd:COG3096   496 TARELLRRYR-------------------------SQQALAQRLQQLRAQLAE-LEQRLRQQQNAERLLEEFCQRIGQQL 549

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1162 SlklANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLdsdngrlgRELADLQGRLALGE 1241
Cdd:COG3096   550 D---AAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAW--------LAAQDALERLREQS 618

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 568931102 1242 RTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQ 1282
Cdd:COG3096   619 GEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQ 659
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
480-881 4.55e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 4.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  480 RKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLS--REKGNLTHSLQVTQQQAKELRQELEKLQ 557
Cdd:COG4717    80 LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELR 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  558 AAQEELKRQHNQLEDAQEDSVQEG-------------------------ARARRELERSHRQLEQLEVKRSGLTKELVEV 612
Cdd:COG4717   160 ELEEELEELEAELAELQEELEELLeqlslateeelqdlaeeleelqqrlAELEEELEEAQEELEELEEELEQLENELEAA 239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  613 REALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEE 692
Cdd:COG4717   240 ALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE 319

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  693 KVALLGRQQQAEHA--TTMAVEKQELLEQLR-LEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQ 769
Cdd:COG4717   320 ELEELLAALGLPPDlsPEELLELLDRIEELQeLLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQE 399

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  770 LSGRDQELEQALRESQRQVEALERAArEKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESS--LFDVQRQL 847
Cdd:COG4717   400 LKEELEELEEQLEELLGELEELLEAL-DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQEL 478

                         410       420       430
                  ....*....|....*....|....*....|....
gi 568931102  848 AQLEARREQLEADSQALLLAKETLTGELAGLRQQ 881
Cdd:COG4717   479 EELKAELRELAEEWAALKLALELLEEAREEYREE 512
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 777-1142 4.77e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 4.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   777 LEQALRESQRQVEALERAAREK-EAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAqlearre 855
Cdd:pfam17380  271 LNQLLHIVQHQKAVSERQQQEKfEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA------- 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   856 qLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMtqklvQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRE 935
Cdd:pfam17380  344 -MERERELERIRQEERKRELERIRQEEIAMEISRMRELERL-----QMERQQKNERVRQELEAARKVKILEEERQRKIQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   936 LQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERdeglllaeseKQQALSLKESEKTALSEKlmgtrhslaai 1015
Cdd:pfam17380  418 QKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQER----------QQQVERLRQQEEERKRKK----------- 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1016 sLEMERQKRDAQSRQEQDRNTLNaltSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREacMREAEELRTQLRVLED 1095
Cdd:pfam17380  477 -LELEKEKRDRKRAEEQRRKILE---KELEERKQAMIEEERKRKLLEKEMEERQKAIYEEER--RREAEEERRKQQEMEE 550

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 568931102  1096 trdglRRELLEAQRKGRDSQDSSEAHRQEaSELRRSLSEGAKEREAL 1142
Cdd:pfam17380  551 -----RRRIQEQMRKATEERSRLEAMERE-REMMRQIVESEKARAEY 591
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
509-958 4.87e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 4.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  509 QAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQeELKRQHNQLEDAQEDSVQEGARArREL 588
Cdd:COG4717    74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL-QLLPLYQELEALEAELAELPERL-EEL 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  589 ERSHRQLEQLEVKRSGLTKELVEVREALscAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKM 668
Cdd:COG4717   152 EERLEELRELEEELEELEAELAELQEEL--EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  669 SALNESLAQDKLElnrliaqleeekvallgRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQ 748
Cdd:COG4717   230 EQLENELEAAALE-----------------ERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  749 ILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIR 828
Cdd:COG4717   293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEI 372

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  829 LRLEKEALESSLFDVQRQLAQLEARREQLEadsqALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQ 908
Cdd:COG4717   373 AALLAEAGVEDEEELRAALEQAEEYQELKE----ELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEEL 448

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 568931102  909 ASLREQRAAHEEDLQRLQHEKEAAwrELQAERAQLQGQLQQEREELLARM 958
Cdd:COG4717   449 EELREELAELEAELEQLEEDGELA--ELLQELEELKAELRELAEEWAALK 496
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 486-1179 5.64e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 48.26  E-value: 5.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  486 SEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELlSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEelKR 565
Cdd:PRK10246  214 TPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDEL-QQEASRRQQALQQALAAEEKAQPQLAALSLAQP--AR 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  566 QHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKelvevrealsCAILQRDVLQTEKAEVAEALTKAEAGRa 645
Cdd:PRK10246  291 QLRPHWERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRH----------HAAKQSAELQAQQQSLNTWLAEHDRFR- 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  646 QLELSLTKLRAEEASLRDSLSKMSALNESLAQDKlelnrliaqleeekvallgRQQQAEHATTMAVEKQELLEQLRLEQE 725
Cdd:PRK10246  360 QWNNELAGWRAQFSQQTSDREQLRQWQQQLTHAE-------------------QKLNALPAITLTLTADEVAAALAQHAE 420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  726 verqglqgslcvaeqaREALEQQILVLRSERSHLQEQLAQLsrqlsgrdQELEQALRESQRQVEALeRAAREKEAMAKER 805
Cdd:PRK10246  421 ----------------QRPLRQRLVALHGQIVPQQKRLAQL--------QVAIQNVTQEQTQRNAA-LNEMRQRYKEKTQ 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  806 AGLAVKlAAAEREGRTLSEEAIRLRLEKEA----LESSLFDVQRQLAQLE-----ARREQLEADSQALLLAKETLTGELA 876
Cdd:PRK10246  476 QLADVK-TICEQEARIKDLEAQRAQLQAGQpcplCGSTSHPAVEAYQALEpgvnqSRLDALEKEVKKLGEEGAALRGQLD 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  877 GLRQQVT-STEEKAALDKElmTQKLVQAEREAQASLREQRAAHEeDLQRLQHEKEAAWRELQ--AERAQLQGQL---QQE 950
Cdd:PRK10246  555 ALTKQLQrDESEAQSLRQE--EQALTQQWQAVCASLNITLQPQD-DIQPWLDAQEEHERQLRllSQRHELQGQIaahNQQ 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  951 REELLARMEAEKEELSKEIAA----LQQERDEGLLLAESEKQ-QALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRD 1025
Cdd:PRK10246  632 IIQYQQQIEQRQQQLLTALAGyaltLPQEDEEASWLATRQQEaQSWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSE 711

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1026 AQSRQEQDRNTLN---ALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREA---EELRTQLRVLEDTrdg 1099
Cdd:PRK10246  712 ETVALDNWRQVHEqclSLHSQLQTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAFLAAlldEETLTQLEQLKQN--- 788

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1100 LRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEE 1179
Cdd:PRK10246  789 LENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQALMQQ 868
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
934-1369 6.08e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 6.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  934 RELQAERAQLQGQLQQER--EELLARMEAEKEELSKEIAALQQERDEglllaESEKQQALSLKESEKTALSEKLMGTRHS 1011
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTEniEELIKEKEKELEEVLREINEISSELPE-----LREELEKLEKEVKELEELKEEIEELEKE 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1012 LAAISLEMERQKRDAQSRQEQdrntLNALTSELRDLRAQLEEATaahaqTVKELEERTGNLGRQREACMREAEELRTQLR 1091
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEER----IEELKKEIEELEEKVKELK-----ELKEKAEEYIKLSEFYEEYLDELREIEKRLS 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1092 VLEDTRDGLRRELLEAQRKgrdsqdsseahRQEASELRRSLSEGAKEREALRRSNEELRSA-VKKAESERISLKLANEDK 1170
Cdd:PRK03918  318 RLEEEINGIEERIKELEEK-----------EERLEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1171 EQKLALLEEARvsvaKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRL---GRELADLQGRLALGERTEKES 1247
Cdd:PRK03918  387 EKLEKELEELE----KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcGRELTEEHRKELLEEYTAELK 462

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1248 RrealgLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARErgllgSLEEARGAEKRL----LDSARSLELRLEAVRA 1323
Cdd:PRK03918  463 R-----IEKELKEIEEKERKLRKELRELEKVLKKESELIKLKE-----LAEQLKELEEKLkkynLEELEKKAEEYEKLKE 532

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 568931102 1324 ETSELGLRLSAAEG---RAQGLEVELARVEAQRRVAEAQLGGLRSALRR 1369
Cdd:PRK03918  533 KLIKLKGEIKSLKKeleKLEELKKKLAELEKKLDELEEELAELLKELEE 581
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
470-776 6.67e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.59  E-value: 6.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  470 EASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKEL 549
Cdd:COG4372    34 RKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEEL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  550 RQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAIL-------- 621
Cdd:COG4372   114 QEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALdellkean 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  622 QRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQ 701
Cdd:COG4372   194 RNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDT 273

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568931102  702 QAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQE 776
Cdd:COG4372   274 EEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 487-805 6.82e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.58  E-value: 6.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   487 EGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQ 566
Cdd:pfam07888   72 ERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   567 HNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQ 646
Cdd:pfam07888  152 LERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   647 LELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVallgrqqQAEHATTMAVEKQELLEQLRLEQEV 726
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARL-------QAAQLTLQLADASLALREGRARWAQ 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   727 ERQGLQGSLCVAEQAREALEQQIL----VLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMA 802
Cdd:pfam07888  305 ERETLQQSAEADKDRIEKLSAELQrleeRLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQ 384


                   ...
gi 568931102   803 KER 805
Cdd:pfam07888  385 AEK 387
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
461-1023 7.64e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 7.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  461 QVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLrdqtaasaqaqEDAQREAQRLRSANELLSREKGNLTHSLQ 540
Cdd:PRK03918  194 LIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-----------EELKEEIEELEKELESLEGSKRKLEEKIR 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  541 VTQQQAKELRQELEKLQAAQEELK------RQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVRE 614
Cdd:PRK03918  263 ELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  615 ALScailQRDVLQTEKAEVAEALTKAEAGRAQLElSLTKLRAEEASLrdSLSKMSALNESLAQDKLELNRLIAQLEEEKV 694
Cdd:PRK03918  343 LKK----KLKELEKRLEELEERHELYEEAKAKKE-ELERLKKRLTGL--TPEKLEKELEELEKAKEEIEEEISKITARIG 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  695 ALLGRQQQAEHATTmavekqelleqlRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEqLAQLSRQLSGRD 774
Cdd:PRK03918  416 ELKKEIKELKKAIE------------ELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKE-IEEKERKLRKEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  775 QELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLfdvqRQLAQLEARR 854
Cdd:PRK03918  483 RELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL----EKLEELKKKL 558

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  855 EQLEADSQALllaketltgelaglrqqvtsTEEKAALDKELmTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAawR 934
Cdd:PRK03918  559 AELEKKLDEL--------------------EEELAELLKEL-EELGFESVEELEERLKELEPFYNEYLELKDAEKEL--E 615

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  935 ELQAERAQLQGQLQQEREElLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAA 1014
Cdd:PRK03918  616 REEKELKKLEEELDKAFEE-LAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694


                  ....*....
gi 568931102 1015 ISLEMERQK 1023
Cdd:PRK03918  695 TLEKLKEEL 703
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1095-1614 8.24e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 8.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1095 DTRDGLRRelLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKL 1174
Cdd:PRK02224  173 DARLGVER--VLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1175 ALLEEarvsVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNgrlgrelADLQGRLALGErtekeSRREALGL 1254
Cdd:PRK02224  251 EELET----LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-------DDLLAEAGLDD-----ADAEAVEA 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1255 RQrllkgeSSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSA 1334
Cdd:PRK02224  315 RR------EELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEE 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1335 AEGRAQGLEVELARVEAQRRVAEAQLGGL---RSALRRGLGLGRVSSSPAREAPAGG-----SGDGLSSPSPLEYSPRSq 1406
Cdd:PRK02224  389 LEEEIEELRERFGDAPVDLGNAEDFLEELreeRDELREREAELEATLRTARERVEEAealleAGKCPECGQPVEGSPHV- 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1407 ppspgliaspappdldpeavrDALRDFLQELRSAQRERDELKVQTSTLSQ------QLVEMEAERDHAASRAKQLQKAVA 1480
Cdd:PRK02224  468 ---------------------ETIEEDRERVEELEAELEDLEEEVEEVEErleraeDLVEAEDRIERLEERREDLEELIA 526

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1481 -------ESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESE---LRASQEKVSKMKATEA 1550
Cdd:PRK02224  527 erretieEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERiesLERIRTLLAAIADAED 606

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568931102 1551 KLESDKRRLKEVLDASESRSIKLELQR---RALEGELQrsrlglGDREAHAQALQDRVDSLQRQVAD 1614
Cdd:PRK02224  607 EIERLREKREALAELNDERRERLAEKRerkRELEAEFD------EARIEEAREDKERAEEYLEQVEE 667
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1430-1895 8.53e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 8.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1430 LRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLsGAQAELALQEESVRR 1509
Cdd:PRK03918  219 LREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV-KELKELKEKAEEYIK 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1510 SKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLEL--QRRALEGELQRS 1587
Cdd:PRK03918  298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeEAKAKKEELERL 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1588 RLGLGDR-----EAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLS 1662
Cdd:PRK03918  378 KKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEY 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1663 STQDKNlhLQKALSTCEHDRQVLQERLDAARQALSEARRQSS--SLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQ 1740
Cdd:PRK03918  458 TAELKR--IEKELKEIEEKERKLRKELRELEKVLKKESELIKlkELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLI 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1741 RQEGEAMALRS----VQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTL 1816
Cdd:PRK03918  536 KLKGEIKSLKKelekLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELE 615

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102 1817 RLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARER 1895
Cdd:PRK03918  616 REEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
742-1054 8.73e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 8.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  742 REALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRT 821
Cdd:COG4372    19 RPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQ 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  822 LSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLV 901
Cdd:COG4372    99 AQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSE 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  902 QAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLL 981
Cdd:COG4372   179 AEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILK 258

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568931102  982 LAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEA 1054
Cdd:COG4372   259 EIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELA 331
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 719-938 1.25e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  719 QLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQEL---EQALRESQRQVEALERAA 795
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  796 REKEAMAKERAGLAVKLAAAEREGRTLSEE--------AIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLA 867
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLLSPEdfldavrrLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568931102  868 KETLTGELAGLRQQVtstEEKAALDKELMTQKlvQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQA 938
Cdd:COG4942   180 LAELEEERAALEALK---AERQKLLARLEKEL--AELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
mukB PRK04863
chromosome partition protein MukB;
1422-1900 1.35e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1422 DPEAVRDALRDFLQELRSAQRERDELK----VQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQ 1497
Cdd:PRK04863  234 DMEAALRENRMTLEAIRVTQSDRDLFKhlitESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMA 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1498 AELALQEESvrrskrecratldqmavlersLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASEsrsiKLELQR 1577
Cdd:PRK04863  314 RELAELNEA---------------------ESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEE----RLEEQN 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1578 RALEGelqrSRLGLGDREAHAQALQDRVDSLQRQVAD-------SEVKAGTLQLTVERLSGA----------LAKVEESE 1640
Cdd:PRK04863  369 EVVEE----ADEQQEENEARAEAAEEEVDELKSQLADyqqaldvQQTRAIQYQQAVQALERAkqlcglpdltADNAEDWL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1641 GNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALS-----TCEHDRQVLQerlDAARQALSEARRQSSsLGEQVQTLRG 1715
Cdd:PRK04863  445 EEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiAGEVSRSEAW---DVARELLRRLREQRH-LAEQLQQLRM 520

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1716 ELASLElQRgdaegqlqqlqqalrqrqegeamaLRSVQKLQEERRLLQERLGS-------LQRALAQLEAEKRDLERSAL 1788
Cdd:PRK04863  521 RLSELE-QR------------------------LRQQQRAERLLAEFCKRLGKnlddedeLEQLQEELEARLESLSESVS 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1789 QFDKDRVALRKTLDKvereklrshedtlrLNAERGRLdrtltgaeldlaeAQQQIQHLEAQVDVALEGNHNPVQPEAGEQ 1868
Cdd:PRK04863  576 EARERRMALRQQLEQ--------------LQARIQRL-------------AARAPAWLAAQDALARLREQSGEEFEDSQD 628

                         490       500       510
                  ....*....|....*....|....*....|...
gi 568931102 1869 QLEL-QQEVERLRSAQVQTERTLEARERAHRQR 1900
Cdd:PRK04863  629 VTEYmQQLLERERELTVERDELAARKQALDEEI 661
mukB PRK04863
chromosome partition protein MukB;
775-1293 1.59e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.87  E-value: 1.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  775 QELEQALRESQRQVEALERAARE----KEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEK-------EALESSLFDV 843
Cdd:PRK04863  233 QDMEAALRENRMTLEAIRVTQSDrdlfKHLITESTNYVAADYMRHANERRVHLEEALELRRELytsrrqlAAEQYRLVEM 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  844 QRQLAQLEARREQLEADSQAlllAKETLTGELAGLRQQvtsteekaaldkelmtqklvQAEREAQASLREQRAAHEEdlq 923
Cdd:PRK04863  313 ARELAELNEAESDLEQDYQA---ASDHLNLVQTALRQQ--------------------EKIERYQADLEELEERLEE--- 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  924 rlqhekeaawrelQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAeSEKQQALSLKESEKTALSe 1003
Cdd:PRK04863  367 -------------QNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRA-IQYQQAVQALERAKQLCG- 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1004 klmgtrhsLAAISLEmerqkrDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEE-RTGNLGRQREACMRE 1082
Cdd:PRK04863  432 --------LPDLTAD------NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLvRKIAGEVSRSEAWDV 497

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1083 AeelrtqlrvledtrdglrRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEelrsavkkaeseRIS 1162
Cdd:PRK04863  498 A------------------RELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCK------------RLG 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1163 LKLANEDKEQKLALLEEARVSvakeagELRASLQEVERSRLEARRELQELRRQMKTLDSdngrLGRELADLQGRLA-LGE 1241
Cdd:PRK04863  548 KNLDDEDELEQLQEELEARLE------SLSESVSEARERRMALRQQLEQLQARIQRLAA----RAPAWLAAQDALArLRE 617

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568931102 1242 RT--EKESRREALGLRQRLLKGESSL-------EALKQELQGSQRKLQEQEAEFRARERGL 1293
Cdd:PRK04863  618 QSgeEFEDSQDVTEYMQQLLERERELtverdelAARKQALDEEIERLSQPGGSEDPRLNAL 678
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1681-1933 2.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1681 DRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEgqlqqlqqalrqrqegeamalRSVQKLQEERR 1760
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---------------------RRIRALEQELA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1761 LLQERLGSLQRALAQLEAEKRDLERSAlqfdKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQ 1840
Cdd:COG4942    80 ALEAELAELEKEIAELRAELEAQKEEL----AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1841 QQIQHLEAQVDVALEGNHNPVQPEAGEQQlELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELR 1920
Cdd:COG4942   156 RADLAELAALRAELEAERAELEALLAELE-EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                         250
                  ....*....|...
gi 568931102 1921 RSSASVSLPPGTP 1933
Cdd:COG4942   235 EAAAAAERTPAAG 247
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1186-1592 2.05e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1186 KEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKES--RREALGLRQRLLKGES 1263
Cdd:COG4717    74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEalEAELAELPERLEELEE 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1264 SLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLE 1343
Cdd:COG4717   154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1344 VELARVEAQRRVAEAQLGGLRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGLIASPAPPDLDP 1423
Cdd:COG4717   234 NELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1424 EAVRDA-LRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQ----------LQKAVAESEEAWRSADRR 1492
Cdd:COG4717   314 EELEEEeLEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLeeleqeiaalLAEAGVEDEEELRAALEQ 393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1493 LSGAQAELALQEESVRRSKRECRATLDQMAV-----LERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASE 1567
Cdd:COG4717   394 AEEYQELKEELEELEEQLEELLGELEELLEAldeeeLEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE 473

                         410       420
                  ....*....|....*....|....*
gi 568931102 1568 SRSIKLELQRRALEGELQRSRLGLG 1592
Cdd:COG4717   474 LLQELEELKAELRELAEEWAALKLA 498
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
526-1102 2.28e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 2.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  526 ELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARaRRELERSHRQLEQLEVKRSGL 605
Cdd:PRK03918  193 ELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESL-EGSKRKLEEKIRELEERIEEL 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  606 TKELVEVREALScAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAqdklELNRL 685
Cdd:PRK03918  272 KKEIEELEEKVK-ELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE----ELKKK 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  686 IAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRlEQEVERqgLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQ 765
Cdd:PRK03918  347 LKELEKRLEELEERHELYEEAKAKKEELERLKKRLT-GLTPEK--LEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  766 LSRQLSgrdqELEQALRESQRQVEALERAAReKEAMAKERAglavKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQR 845
Cdd:PRK03918  424 LKKAIE----ELKKAKGKCPVCGRELTEEHR-KELLEEYTA----ELKRIEKELKEIEEKERKLRKELRELEKVLKKESE 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  846 QLAQLEARREQLEADSQALLLAKETLtgelaglrqqvtsteEKAALDKELMTQKLvqAEREAQASLREQRAAHEEDLQRL 925
Cdd:PRK03918  495 LIKLKELAEQLKELEEKLKKYNLEEL---------------EKKAEEYEKLKEKL--IKLKGEIKSLKKELEKLEELKKK 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  926 QHEKEAAWRELQAERAQLQGQLQQEREELLarmeaekEELSKEIAALQQERDEGLLL--AESEKQQALSLKESEKTALS- 1002
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELEELGFESV-------EELEERLKELEPFYNEYLELkdAEKELEREEKELKKLEEELDk 630

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1003 --EKLMGTRHSLAAISLEMER-QKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREAc 1079
Cdd:PRK03918  631 afEELAETEKRLEELRKELEElEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA- 709

                         570       580
                  ....*....|....*....|...
gi 568931102 1080 MREAEELRTQLRVLEDTRDGLRR 1102
Cdd:PRK03918  710 KKELEKLEKALERVEELREKVKK 732
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 480-998 2.42e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 46.28  E-value: 2.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   480 RKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSAnelLSREKGNLTHSLQVTQQQAKEL-RQELEKLQA 558
Cdd:pfam07111  161 EEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQ---LSKTQEELEAQVTLVESLRKYVgEQVPPEVHS 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   559 AQEELKRQHnqledaQEDSVQEGARARRELERShrqLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALT 638
Cdd:pfam07111  238 QTWELERQE------LLDTMQHLQEDRADLQAT---VELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFPKKCRSLL 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   639 KaeAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQdklelnRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLE 718
Cdd:pfam07111  309 N--RWREKVFALMVQLKAQDLEHRDSVKQLRGQVAELQE------QVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQM 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   719 QLRLEQEVERQGLQGSLCVAEQareaLEQQILVLRSERSHLQEQLAQLSrQLSGRDQELEQALRESQRQVEALERAAREK 798
Cdd:pfam07111  381 ELSRAQEARRRQQQQTASAEEQ----LKFVVNAMSSTQIWLETTMTRVE-QAVARIPSLSNRLSYAVRKVHTIKGLMARK 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   799 EAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEAR-REQLEADSQALLLAKETLTGEL-- 875
Cdd:pfam07111  456 VALAQLRQESCPPPPPAPPVDADLSLELEQLREERNRLDAELQLSAHLIQQEVGRaREQGEAERQQLSEVAQQLEQELqr 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   876 -------------AGLRQQVTSTEEKAALDKELMTQK------LVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWREL 936
Cdd:pfam07111  536 aqeslasvgqqleVARQGQQESTEEAASLRQELTQQQeiygqaLQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSL 615

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568931102   937 QaeRAQLQGQLQQEREELLARM--EAEKEELSKEIAALQQ-ERDEGLLLAESEKQQALSLKESEK 998
Cdd:pfam07111  616 R--QIQHRATQEKERNQELRRLqdEARKEEGQRLARRVQElERDKNLMLATLQQEGLLSRYKQQR 678
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
637-1078 2.52e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 46.05  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  637 LTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKV-ALLGRQQQAEHATTMAVEKQE 715
Cdd:COG5278    78 LEPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLeAALALVRSGEGKALMDEIRAR 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  716 LLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAA 795
Cdd:COG5278   158 LLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAA 237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  796 REKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGEL 875
Cdd:COG5278   238 LALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAA 317

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  876 AGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELL 955
Cdd:COG5278   318 AAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAA 397

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  956 ARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRN 1035
Cdd:COG5278   398 AAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAAL 477

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 568931102 1036 TLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREA 1078
Cdd:COG5278   478 AAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAA 520
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 780-961 2.88e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 2.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  780 ALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEA 859
Cdd:COG1579     1 AMPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  860 DSQALLLAKE--TLTGELAGLRQQVTSTEEKAaldKELMTQklVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQ 937
Cdd:COG1579    81 QLGNVRNNKEyeALQKEIESLKRRISDLEDEI---LELMER--IEELEEELAELEAELAELEAELEEKKAELDEELAELE 155

                         170       180
                  ....*....|....*....|....
gi 568931102  938 AERAqlqgQLQQEREELLARMEAE 961
Cdd:COG1579   156 AELE----ELEAEREELAAKIPPE 175
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1036-1278 3.20e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1036 TLNALTSELRDLRAQLEEATAAHAQTVKELEErtgnLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQ 1115
Cdd:COG4942    14 AAAAQADAAAEAEAELEQLQQEIAELEKELAA----LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1116 DSSEAHRQEASELRRSLSegakerealrrsnEELRSAVKKAESERISLKLANEDKEQ---KLALLEEARVSVAKEAGELR 1192
Cdd:COG4942    90 KEIAELRAELEAQKEELA-------------ELLRALYRLGRQPPLALLLSPEDFLDavrRLQYLKYLAPARREQAEELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1193 ASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQEL 1272
Cdd:COG4942   157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                  ....*.
gi 568931102 1273 QGSQRK 1278
Cdd:COG4942   237 AAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1412-1638 3.43e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1412 LIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADR 1491
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1492 RLSGAQAELALQEES----VRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASE 1567
Cdd:COG4942    91 EIAELRAELEAQKEElaelLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568931102 1568 SRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEE 1638
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 79-806 3.65e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 3.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    79 EQSSYRRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLRLEEEQQRSA 158
Cdd:TIGR00618  160 AKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQ 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   159 SLAQVNAMLREQLDQANLANQALSEDIRKvtsdwtrsCKELEQREAVWRREEESFNtyFSSEHSRLLRLWRQVMGLRRQA 238
Cdd:TIGR00618  240 QSHAYLTQKREAQEEQLKKQQLLKQLRAR--------IEELRAQEAVLEETQERIN--RARKAAPLAAHIKAVTQIEQQA 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   239 SEVKMGTERDLLQLGGELVRTSRAVQ-----ELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQ---LQAKLLREKDLA 310
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKqqssiEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQhtlTQHIHTLQQQKT 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   311 QLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEGLQQTLRDLAQAALS 390
Cdd:TIGR00618  390 TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   391 DTESGVQLSSSERTADTSDGSLRGFSGQRTPTPPRHSPGRGRSPRRGLspacsdssTLTLIHSALHKRQLQVQDmrgRYE 470
Cdd:TIGR00618  470 EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPAR--------QDIDNPGPLTRRMQRGEQ---TYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   471 ASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREkgnLTHSLQVTQQQAKELR 550
Cdd:TIGR00618  539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDL---TEKLSEAEDMLACEQH 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   551 QELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEK 630
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   631 AEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKleLNRLIAQLEEEKVALLGRQQQAEHATTMA 710
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQS--LKELMHQARTVLKARTEAHFNNNEEVTAA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   711 VEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEA 790
Cdd:TIGR00618  774 LQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLK 853

                          730
                   ....*....|....*.
gi 568931102   791 LERAAREKEAMAKERA 806
Cdd:TIGR00618  854 YEECSKQLAQLTQEQA 869
PRK09039 PRK09039
peptidoglycan -binding protein;
1602-1721 3.93e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.96  E-value: 3.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1602 QDRVDSLQRQVAD-------SEVKAGTLQLTVERLSGALAKVEesegNLRSKVQSLTDALTQSSASLsstqdknlhlqka 1674
Cdd:PRK09039   52 DSALDRLNSQIAEladllslERQGNQDLQDSVANLRASLSAAE----AERSRLQALLAELAGAGAAA------------- 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 568931102 1675 lstcEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLE 1721
Cdd:PRK09039  115 ----EGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALE 157
mukB PRK04863
chromosome partition protein MukB;
710-1133 4.45e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 4.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  710 AVEKQELLEQlRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLsgrdqeleQALRESQRQVE 789
Cdd:PRK04863  278 ANERRVHLEE-ALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL--------NLVQTALRQQE 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  790 ALERAAREKEAM--AKERAGLAVKLAAAEREGRtlSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQAL--- 864
Cdd:PRK04863  349 KIERYQADLEELeeRLEEQNEVVEEADEQQEEN--EARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALera 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  865 --LLAKETLTGELAGLRQQVTSTEEKAALDKELMT-QKLVQAE----REAQASLREQRAAHE---EDLQRLQHEKEAAWR 934
Cdd:PRK04863  427 kqLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLeQKLSVAQaahsQFEQAYQLVRKIAGEvsrSEAWDVARELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  935 ELQAERAQLQgQLQQEREELLARmeaekeelskeiaaLQQERDEGLLLAESEKQQALSL-KESEKTALSEKLMGTRHSLa 1013
Cdd:PRK04863  507 EQRHLAEQLQ-QLRMRLSELEQR--------------LRQQQRAERLLAEFCKRLGKNLdDEDELEQLQEELEARLESL- 570

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1014 aislemERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAqTVKELEERTGnlgrqreacmreaEELRTQLRVl 1093
Cdd:PRK04863  571 ------SESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQD-ALARLREQSG-------------EEFEDSQDV- 629

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 568931102 1094 edtrDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLS 1133
Cdd:PRK04863  630 ----TEYMQQLLERERELTVERDELAARKQALDEEIERLS 665
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1474-1900 4.71e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 4.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1474 QLQKAVAESEEAwrSADRRLSGAQAELALQEESVRR---SKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEA 1550
Cdd:PRK02224  191 QLKAQIEEKEEK--DLHERLNGLESELAELDEEIERyeeQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1551 KLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLS 1630
Cdd:PRK02224  269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1631 GALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEH-------DRQVLQERLDAARQALSEARRQS 1703
Cdd:PRK02224  349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdapvDLGNAEDFLEELREERDELRERE 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1704 SSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEaekrDL 1783
Cdd:PRK02224  429 AELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE----DL 504

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1784 ERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNhnpvqp 1863
Cdd:PRK02224  505 VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELN------ 578

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 568931102 1864 eagEQQLELQQEVERLRSAQVQTERTLEARERAHRQR 1900
Cdd:PRK02224  579 ---SKLAELKERIESLERIRTLLAAIADAEDEIERLR 612
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 457-1034 4.78e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 4.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   457 KRQLQVQDMRGRYEASQELLGSVRKQlsdseGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLT 536
Cdd:TIGR00618  257 KKQQLLKQLRARIEELRAQEAVLEET-----QERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRA 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   537 HSLQvtQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVR--- 613
Cdd:TIGR00618  332 AHVK--QQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQreq 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   614 -----EALSCAILQRDVLQTEKAEVAEaLTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKlelnrLIAQ 688
Cdd:TIGR00618  410 atidtRTSAFRDLQGQLAHAKKQQELQ-QRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE-----QIHL 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   689 LEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSR 768
Cdd:TIGR00618  484 QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKE 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   769 QLSGRDQELE-----------------------------------QALRESQRQVEALERAAREKEAMAKER---AGLAV 810
Cdd:TIGR00618  564 QMQEIQQSFSiltqcdnrskedipnlqnitvrlqdlteklseaedMLACEQHALLRKLQPEQDLQDVRLHLQqcsQELAL 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   811 KLAAAEREGRTLSEEAIR--LRLEKEALESSLFDVQRQLAQLEARREQLEAD------SQALLLAKETLTGELAGLRQQV 882
Cdd:TIGR00618  644 KLTALHALQLTLTQERVRehALSIRVLPKELLASRQLALQKMQSEKEQLTYWkemlaqCQTLLRELETHIEEYDREFNEI 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   883 TSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRlQHEKEAAWRELQAERAQLQGQLQQEREELlarmEAEK 962
Cdd:TIGR00618  724 ENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFN-NNEEVTAALQTGAELSHLAAEIQFFNRLR----EEDT 798

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568931102   963 EELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDR 1034
Cdd:TIGR00618  799 HLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
495-921 5.13e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 44.90  E-value: 5.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  495 EQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQ 574
Cdd:COG5278   104 EQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALA 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  575 EDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKL 654
Cdd:COG5278   184 ALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALL 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  655 RAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGS 734
Cdd:COG5278   264 AAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAAA 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  735 LCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAA 814
Cdd:COG5278   344 LALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALE 423

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  815 AEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKE 894
Cdd:COG5278   424 LAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLAL 503

                         410       420
                  ....*....|....*....|....*..
gi 568931102  895 LMTQKLVQAEREAQASLREQRAAHEED 921
Cdd:COG5278   504 ALAALLLAAAEAALAAALAAALASAEL 530
PRK09039 PRK09039
peptidoglycan -binding protein;
1212-1359 5.28e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.57  E-value: 5.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1212 LRRQMKTLDSDNGRLGRELADLQGRLALgERTEKESRREALGlrqRLLKGESSLEALKQELQGSQRKLQEQEAEFRARER 1291
Cdd:PRK09039   44 LSREISGKDSALDRLNSQIAELADLLSL-ERQGNQDLQDSVA---NLRASLSAAEAERSRLQALLAELAGAGAAAEGRAG 119

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568931102 1292 GLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQ 1359
Cdd:PRK09039  120 ELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIADLGRRLNVALAQ 187
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1509-1856 6.20e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 6.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1509 RSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVldasesRSIKLELQRRALEGELQRSR 1588
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREY------EGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1589 LGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSgalakvEESEGNLRSKVQSLTDALTQSSASLSSTQDKN 1668
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG------EEEQLRVKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1669 LHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLqqlqqalrqrqegeAMA 1748
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF--------------AET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1749 LRSVQKLQEERRLLQERLGSLQR--------------ALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHED 1814
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKReldrlqeelqrlseELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 568931102  1815 TLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEG 1856
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 780-1076 7.99e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.83  E-value: 7.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  780 ALRESQRQVEALERAAREKEAMAKeraglavklAAAEREgrtlSEEAIRLRLEKEAlesslfdvQRQLAQLEARREQLEA 859
Cdd:NF012221 1536 ATSESSQQADAVSKHAKQDDAAQN---------ALADKE----RAEADRQRLEQEK--------QQQLAAISGSQSQLES 1594

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  860 DSQALLlaketltgELAGLRQQVTSTEEKAALDKEL--MTQKLVQAEREAQAS------LREQRAahEEDLQRLQHE--- 928
Cdd:NF012221 1595 TDQNAL--------ETNGQAQRDAILEESRAVTKELttLAQGLDALDSQATYAgesgdqWRNPFA--GGLLDRVQEQldd 1664

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  929 -KEAAWRELQAERAQLQGQLQQEREElLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKlmg 1007
Cdd:NF012221 1665 aKKISGKQLADAKQRHVDNQQKVKDA-VAKSEAGVAQGEQNQANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDA--- 1740

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102 1008 trHSLAaislemerqkRDAQSRQEQDrntlnALTSELRDLRAQleeataAHAQTVKELEERTGNlgRQR 1076
Cdd:NF012221 1741 --NAAA----------NDAQSRGEQD-----ASAAENKANQAQ------ADAKGAKQDESDKPN--RQG 1784
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
953-1379 8.97e-04

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 44.22  E-value: 8.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  953 ELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQ 1032
Cdd:COG5281     2 AALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1033 DRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREAcMREAEELRTQLRVLEDTRDGLRRELLEAQRKGR 1112
Cdd:COG5281    82 AALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAAA-AAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1113 DSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARvSVAKEAGELR 1192
Cdd:COG5281   161 AAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAA-ALAEQAALAA 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1193 ASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQEL 1272
Cdd:COG5281   240 ASAAAQALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1273 QGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGL----EVELAR 1348
Cdd:COG5281   320 AAQALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALaeyaDSATNV 399

                         410       420       430
                  ....*....|....*....|....*....|.
gi 568931102 1349 VEAQRRVAEAQLGGLRSALRRGLGLGRVSSS 1379
Cdd:COG5281   400 AAQVAQAATSAFSGLTDALAGAVTTGKLLFD 430
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
898-1346 9.89e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 44.13  E-value: 9.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  898 QKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERD 977
Cdd:COG5278    82 EEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLL 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  978 EGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAA 1057
Cdd:COG5278   162 ALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALA 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1058 HAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAK 1137
Cdd:COG5278   242 LALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAA 321

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1138 EREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMK 1217
Cdd:COG5278   322 AAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAA 401

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1218 TLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSL 1297
Cdd:COG5278   402 AAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAA 481

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 568931102 1298 EEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVEL 1346
Cdd:COG5278   482 AALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 487-967 1.14e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 43.96  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   487 EGERRGLEEQLQRLRDQTAASAQAQeDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQ 566
Cdd:pfam05557   17 EKKQMELEHKRARIELEKKASALKR-QLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEK 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   567 HNQLEDAQEDSV---QEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEA------L 637
Cdd:pfam05557   96 ESQLADAREVISclkNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAeqrikeL 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   638 TKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKlELNRLIAQLEEEKVAL---LGRQQQA-EHATTMAVEK 713
Cdd:pfam05557  176 EFEIQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLN-ENIENKLLLKEEVEDLkrkLEREEKYrEEAATLELEK 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   714 QELLEQLRLEQEVErQGLQGSLCVAEQAR---EALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALR-------E 783
Cdd:pfam05557  255 EKLEQELQSWVKLA-QDTGLNLRSPEDLSrriEQLQQREIVLKEENSSLTSSARQLEKARRELEQELAQYLKkiedlnkK 333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   784 SQRQVEALERAAREKEAMAKERAGLAVKLAAAEREgRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQA 863
Cdd:pfam05557  334 LKRHKALVRRLQRRVLLLTKERDGYRAILESYDKE-LTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGG 412

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   864 LLLAKETLTGELAGLRQQV------TSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQ-------RLQHEKE 930
Cdd:pfam05557  413 YKQQAQTLERELQALRQQEsladpsYSKEEVDSLRRKLETLELERQRLREQKNELEMELERRCLQGdydpkktKVLHLSM 492

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 568931102   931 AAWRELQAERAQLQGQLQQEREELLARMEAEKEELSK 967
Cdd:pfam05557  493 NPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQ 529
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 461-650 1.24e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  461 QVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELL----SREKGNLT 536
Cdd:COG4942    56 QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAV 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  537 HSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQedsvQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREAL 616
Cdd:COG4942   136 RRLQYLKYLAPARREQAEELRADLAELAALRAELEAER----AELEALLAELEEERAALEALKAERQKLLARLEKELAEL 211

                         170       180       190
                  ....*....|....*....|....*....|....
gi 568931102  617 SCAILQRDVLQTEKAEVAEALTKAEAGRAQLELS 650
Cdd:COG4942   212 AAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 900-1328 1.27e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.94  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   900 LVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREellarMEAEKEELSKEIAALQQERDEg 979
Cdd:pfam05483  262 LLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKA-----LEEDLQIATKTICQLTEEKEA- 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   980 lllaesekqqalSLKESEKTALSEKLMGTRhsLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHA 1059
Cdd:pfam05483  336 ------------QMEELNKAKAAHSFVVTE--FEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKN 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1060 QTVKELEERTGNLGrQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKER 1139
Cdd:pfam05483  402 NKEVELEELKKILA-EDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTEL 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1140 EALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKtl 1219
Cdd:pfam05483  481 EKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFI-- 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1220 dsdngrlgRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEE 1299
Cdd:pfam05483  559 --------QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQ 630

                          410       420
                   ....*....|....*....|....*....
gi 568931102  1300 ARGAEKRLldsaRSLELRLEAVRAETSEL 1328
Cdd:pfam05483  631 LNAYEIKV----NKLELELASAKQKFEEI 655
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1037-1160 1.31e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.69  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1037 LNALTSELRDLRAQLEEATAAHAQT-VKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQ 1115
Cdd:COG2433   382 LEELIEKELPEEEPEAEREKEHEEReLTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREI 461

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 568931102 1116 DSS---EAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESER 1160
Cdd:COG2433   462 RKDreiSRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 56-857 1.51e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 1.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    56 ELEAQEPRGLVRQSVELRRQLQEEQSSYRRKLQAYQEGQQRQAQLVQRLQaKILQYKKQCSELEKQLMDRSTELEQQRLR 135
Cdd:pfam02463  194 ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ-ELLRDEQEEIESSKQEIEKEEEKLAQVLK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   136 DTE------HSQDLDSALLRLEEEQQRSA--SLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVwR 207
Cdd:pfam02463  273 ENKeeekekKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIK-R 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   208 REEESFNTYFSSEHSRLLRLWRQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELglglsasLHRAESKAEAALEK 287
Cdd:pfam02463  352 EAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL-------LELARQLEDLLKEE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   288 QKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTL---SDKLEALESLRLQ 364
Cdd:pfam02463  425 KKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELllsRQKLEERSQKESK 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   365 EQTTLDTEDGEGLQQTLRDLAQAALSDTESGVQLSSSERTADTSDGSLRGFSGQ--------RTPTPPRHSPGRGRSPRR 436
Cdd:pfam02463  505 ARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADeveerqklVRALTELPLGARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   437 GLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQR 516
Cdd:pfam02463  585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   517 EAQRLRSANELL-SREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQE-GARARRELERSHRQ 594
Cdd:pfam02463  665 KASLSELTKELLeIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEaQDKINEELKLLKQK 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   595 LEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEvAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNES 674
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK-TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLL 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   675 LAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRS 754
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELE 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   755 ERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAR-EKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEK 833
Cdd:pfam02463  904 EESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEAdEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEF 983

                          810       820
                   ....*....|....*....|....
gi 568931102   834 EALESSLFDVQRQLAQLEARREQL 857
Cdd:pfam02463  984 EEKEERYNKDELEKERLEEEKKKL 1007
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1126-1633 1.75e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 1.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1126 SELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLklanEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEA 1205
Cdd:PRK03918  196 KEKEKELEEVLREINEISSELPELREELEKLEKEVKEL----EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1206 RRELQELRRQMKtldsdngrlgrELADLQGRLALGERTEKESRRealgLRQRLLKGESSLEALKQELQGSQRKLQEQEA- 1284
Cdd:PRK03918  272 KKEIEELEEKVK-----------ELKELKEKAEEYIKLSEFYEE----YLDELREIEKRLSRLEEEINGIEERIKELEEk 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1285 -----EFRARERGLLGSLEEARGAEKrLLDSARSLELRLEAVRAETSELGL-----RLSAAEGRAQGLEVELARVEAQRR 1354
Cdd:PRK03918  337 eerleELKKKLKELEKRLEELEERHE-LYEEAKAKKEELERLKKRLTGLTPeklekELEELEKAKEEIEEEISKITARIG 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1355 VAEAQLGGLRSALRRGLGLGRVSSSPAREapaggsgdglsspspleysprsqppspgliaspappdLDPEAVRDALRDFL 1434
Cdd:PRK03918  416 ELKKEIKELKKAIEELKKAKGKCPVCGRE-------------------------------------LTEEHRKELLEEYT 458

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1435 QELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAvaeseEAWRSADRRLSGaqaelaLQEESVRRSKREC 1514
Cdd:PRK03918  459 AELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELA-----EQLKELEEKLKK------YNLEELEKKAEEY 527

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1515 RATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIK----LELQRRALEgELQRSRLG 1590
Cdd:PRK03918  528 EKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFEsveeLEERLKELE-PFYNEYLE 606

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 568931102 1591 LGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGAL 1633
Cdd:PRK03918  607 LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKEL 649
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
455-759 1.82e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  455 LHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGN 534
Cdd:COG4372    61 LEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAE 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  535 LTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQE----DSVQEGARARRELERSHRQLEQLEVKRSGLTKELV 610
Cdd:COG4372   141 LQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAeqalDELLKEANRNAEKEEELAEAEKLIESLPRELAEEL 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  611 EVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLE 690
Cdd:COG4372   221 LEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLAL 300

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102  691 EEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHL 759
Cdd:COG4372   301 LLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVAD 369
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
656-990 1.96e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  656 AEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEVERQGL---Q 732
Cdd:COG4372    28 ALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELeslQ 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  733 GSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKL 812
Cdd:COG4372   108 EEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDE 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  813 AAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALD 892
Cdd:COG4372   188 LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAI 267

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  893 KELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAAL 972
Cdd:COG4372   268 LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLL 347

                         330
                  ....*....|....*...
gi 568931102  973 QQERDEGLLLAESEKQQA 990
Cdd:COG4372   348 VGLLDNDVLELLSKGAEA 365
growth_prot_Scy NF041483
polarized growth protein Scy;
687-1211 2.30e-03

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 43.28  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  687 AQLEEEKVALLGRQQQAEHATTMAVEKQELLEQLRLEQEverQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQL 766
Cdd:NF041483  183 ARAEAERLAEEARQRLGSEAESARAEAEAILRRARKDAE---RLLNAASTQAQEATDHAEQLRSSTAAESDQARRQAAEL 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  767 SRQLSGRDQELEQALRESQRQVEALEraarekeAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSlfdvqrq 846
Cdd:NF041483  260 SRAAEQRMQEAEEALREARAEAEKVV-------AEAKEAAAKQLASAESANEQRTRTAKEEIARLVGEATKEA------- 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  847 lAQLEARREQLEADSQAlllAKETLTGELAGLRQQVTSTEEKAALDKELMTQK--LVQAEREAQASLReqraAHEEDLQR 924
Cdd:NF041483  326 -EALKAEAEQALADARA---EAEKLVAEAAEKARTVAAEDTAAQLAKAARTAEevLTKASEDAKATTR----AAAEEAER 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  925 LQHEKEAAWRELQAERA----QLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGL-----LLAESEKQQALSLKE 995
Cdd:NF041483  398 IRREAEAEADRLRGEAAdqaeQLKGAAKDDTKEYRAKTVELQEEARRLRGEAEQLRAEAVaegerIRGEARREAVQQIEE 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  996 SEKTA---LSEKLMGTRHSLAAISLEMERQKRDAQSR----QEQDRNTLNALTSELRDLRAQLEE-ATAAHAQTVKELEE 1067
Cdd:NF041483  478 AARTAeelLTKAKADADELRSTATAESERVRTEAIERattlRRQAEETLERTRAEAERLRAEAEEqAEEVRAAAERAARE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1068 RTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELL-----EAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREAL 1142
Cdd:NF041483  558 LREETERAIAARQAEAAEELTRLHTEAEERLTAAEEALadaraEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAER 637

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568931102 1143 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQE 1211
Cdd:NF041483  638 LRTEAAADASAARAEGENVAVRLRSEAAAEAERLKSEAQESADRVRAEAAAAAERVGTEAAEALAAAQE 706
mukB PRK04863
chromosome partition protein MukB;
956-1307 2.34e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  956 ARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSL-KESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDR 1034
Cdd:PRK04863  275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMaRELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQ 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1035 NTLNALTselrdlrAQLEEATAAhaqtVKELEErtgnlgrqreacmrEAEELRTQLRVLEDTRDGLRRELLEAQRKGRDS 1114
Cdd:PRK04863  355 ADLEELE-------ERLEEQNEV----VEEADE--------------QQEENEARAEAAEEEVDELKSQLADYQQALDVQ 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1115 QDSSEAHRQEASELRRSlsEGAKEREALRRSNEELRSAVKKAESERISLKLanEDKEQKLALLEEARVSVAKEAGELRAS 1194
Cdd:PRK04863  410 QTRAIQYQQAVQALERA--KQLCGLPDLTADNAEDWLEEFQAKEQEATEEL--LSLEQKLSVAQAAHSQFEQAYQLVRKI 485

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1195 LQEVERSRL-EARRELQELRRQMKTLDSDNGRLGRELADLQGRLALgERTEKESRREALGLRQRLLKGESSLEALKQELQ 1273
Cdd:PRK04863  486 AGEVSRSEAwDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQ-QQRAERLLAEFCKRLGKNLDDEDELEQLQEELE 564

                         330       340       350
                  ....*....|....*....|....*....|....
gi 568931102 1274 GSQRKLQEQEAEFRARERGLLGSLEEARGAEKRL 1307
Cdd:PRK04863  565 ARLESLSESVSEARERRMALRQQLEQLQARIQRL 598
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 779-883 2.34e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 2.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  779 QALRESQRQVEALERaarEKEAMAKER-AGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQL 857
Cdd:COG0542   411 EELDELERRLEQLEI---EKEALKKEQdEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRYGKI 487

                          90       100
                  ....*....|....*....|....*.
gi 568931102  858 EADSQALLLAKETLTGELAGLRQQVT 883
Cdd:COG0542   488 PELEKELAELEEELAELAPLLREEVT 513
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
540-867 2.40e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 2.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  540 QVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEdsvqEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCA 619
Cdd:COG4372    24 ILIAALSEQLRKALFELDKLQEELEQLREELEQARE----ELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  620 ILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGR 699
Cdd:COG4372   100 QEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEA 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  700 QQQAE------HATTMAVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGR 773
Cdd:COG4372   180 EAEQAldellkEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKE 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  774 DQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEAR 853
Cdd:COG4372   260 IEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAEL 339

                         330
                  ....*....|....
gi 568931102  854 REQLEADSQALLLA 867
Cdd:COG4372   340 ADLLQLLLVGLLDN 353
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1491-1928 2.43e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.90  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1491 RRLSGAQAELALQEESVRRSKRECRATLDQM----------AVLERSLQATESELRASQEKVSKMKAT-EAKLESDKR-- 1557
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDRQLAVAEDDLQALeselreqleaGKLEFNEEEYRLKSRLGELKLRLNQATaTPELLLQLEnf 469

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1558 -----RLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADsevKAGTLqltVERLSGA 1632
Cdd:pfam12128  470 derieRAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFP---QAGTL---LHFLRKE 543

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1633 LAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKN-----LHLQKALSTCEHD-RQVLQERLDAARQALSEARRQSSSL 1706
Cdd:pfam12128  544 APDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNlygvkLDLKRIDVPEWAAsEEELRERLDKAEEALQSAREKQAAA 623

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1707 GEQVQTLRGELASLELQRGDA-EGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRD-LE 1784
Cdd:pfam12128  624 EEQLVQANGELEKASREETFArTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAwLE 703

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1785 RSALQFDKDRVALRKTLDKVEREKlrshedtlrlNAERGRLDRTLTGAELDLAEAQQQIQHlEAQVDVALEGNHNPVQPE 1864
Cdd:pfam12128  704 EQKEQKREARTEKQAYWQVVEGAL----------DAQLALLKAAIAARRSGAKAELKALET-WYKRDLASLGVDPDVIAK 772

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568931102  1865 AGEQQLELQQEVERL---RSAQVQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELRRSSASVSL 1928
Cdd:pfam12128  773 LKREIRTLERKIERIavrRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKL 839
PstA COG4985
ABC-type phosphate transport system, auxiliary component PstA [Inorganic ion transport and ...
 695-774 2.51e-03

ABC-type phosphate transport system, auxiliary component PstA [Inorganic ion transport and metabolism];


Pssm-ID: 444009 [Multi-domain]  Cd Length: 545  Bit Score: 42.60  E-value: 2.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  695 ALLGRQQQAE--HATTMAVEKQEL------LEQLRLEQevERQGLQGSLCVAEQAReaLEQQILVLRSERSHLQEQLAQL 766
Cdd:COG4985   159 ELQQRLERALelRDQIDDIEKGDIgainyqLERLRLKE--RRLELDGQLDDEAQAD--IEAERAELEAEYAVLEQQLDAL 234


                  ....*...
gi 568931102  767 sRQLSGRD 774
Cdd:COG4985   235 -RQQINRD 241
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 98-840 2.72e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 2.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    98 AQLVQRLQAKILQYKKQCSELEKQLMDRSTELEQQRLRDTEHSQDLDSALLrlEEEQQRSASLAQVNAMLREQLDQANLA 177
Cdd:pfam15921  223 SKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLI--SEHEVEITGLTEKASSARSQANSIQSQ 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   178 NQALSEDIRKVTSDWTRSCKELEQREAVWRRE-EESFNTYfsseHSRLLRLWRQVMGLRRQASEVKmgTERDllQLGGEL 256
Cdd:pfam15921  301 LEIIQEQARNQNSMYMRQLSDLESTVSQLRSElREAKRMY----EDKIEELEKQLVLANSELTEAR--TERD--QFSQES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   257 VRTSRAVQELglglSASLHRAESKAEAALEKQKLL--QAQLEEQLQAKLLREKDLAQLQVQ--SDLDKADLSARVTELAL 332
Cdd:pfam15921  373 GNLDDQLQKL----LADLHKREKELSLEKEQNKRLwdRDTGNSITIDHLRRELDDRNMEVQrlEALLKAMKSECQGQMER 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   333 SVEHLQNQNSEKDQVNrTLSDKLEALESL--RLQEQTTLDTEDGEGLQQTLRDLAqAALSDTESGVQLSSSERTADTSDG 410
Cdd:pfam15921  449 QMAAIQGKNESLEKVS-SLTAQLESTKEMlrKVVEELTAKKMTLESSERTVSDLT-ASLQEKERAIEATNAEITKLRSRV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   411 SLRGFSGQRTPTPPRHSPgRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELlgsVRKQLSDSEGER 490
Cdd:pfam15921  527 DLKLQELQHLKNEGDHLR-NVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQV---EKAQLEKEINDR 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   491 RGLEEQLQRLRDQTAASAQAQE----DAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQ 566
Cdd:pfam15921  603 RLELQEFKILKDKKDAKIRELEarvsDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRN 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   567 HNQLEDAQEDSVQ----EGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEA 642
Cdd:pfam15921  683 FRNKSEEMETTTNklkmQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANK 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   643 GRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEeekVALlgrqqqaEHATTMAVEKQELLEqlRL 722
Cdd:pfam15921  763 EKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME---VAL-------DKASLQFAECQDIIQ--RQ 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   723 EQEVERQGLQGSLCVAE------QAREALEQQILVLRS-ERSHLQEQLAQLSRQLSGRDQELEQALRESqrQVEALERAA 795
Cdd:pfam15921  831 EQESVRLKLQHTLDVKElqgpgyTSNSSMKPRLLQPASfTRTHSNVPSSQSTASFLSHHSRKTNALKED--PTRDLKQLL 908

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 568931102   796 REKEAMAKERAglAVKLAAAEREGRTLSEEAIRLRLEKEALESSL 840
Cdd:pfam15921  909 QELRSVINEEP--TVQLSKAEDKGRAPSLGALDDRVRDCIIESSL 951
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1082-1291 3.47e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 3.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1082 EAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKkaeseRI 1161
Cdd:PRK10929   24 DEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPR-----SV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1162 SLKLANEDKEQKL-----ALLEEARVSVAK--EAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGR-ELADL 1233
Cdd:PRK10929   99 PPNMSTDALEQEIlqvssQLLEKSRQAQQEqdRAREISDSLSQLPQQQTEARRQLNEIERRLQTLGTPNTPLAQaQLTAL 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568931102 1234 QGRLALGERTEKE---------SRREALGLRQRLLKGESS-LEALKQELQGSQRKLQEQEAEfRARER 1291
Cdd:PRK10929  179 QAESAALKALVDElelaqlsanNRQELARLRSELAKKRSQqLDAYLQALRNQLNSQRQREAE-RALES 245
PRK10920 PRK10920
putative uroporphyrinogen III C-methyltransferase; Provisional
 747-814 3.52e-03

putative uroporphyrinogen III C-methyltransferase; Provisional


Pssm-ID: 236795  Cd Length: 390  Bit Score: 42.01  E-value: 3.52e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568931102  747 QQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALresQRQVEALERAAREKEAMAKERAGLAVKLAA 814
Cdd:PRK10920   60 QQAQNQTATNDALANQLTALQKAQESQKQELEGIL---KQQAKALDQANRQQAALAKQLDELQQKVAT 124
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 622-863 3.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 3.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  622 QRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQ 701
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  702 QaehattmavEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILvlrsershlqeqLAQLSRQLSGRDQELEQAL 781
Cdd:COG4942   101 A---------QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQY------------LKYLAPARREQAEELRADL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  782 RESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEeaiRLRLEKEALESSLFDVQRQLAQLEARREQLEADS 861
Cdd:COG4942   160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLA---RLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                  ..
gi 568931102  862 QA 863
Cdd:COG4942   237 AA 238
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1017-1542 4.95e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 4.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1017 LEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELeertgnLGRQREACMREAEELRTQLRVLEDT 1096
Cdd:COG4913   244 LEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL------LEAELEELRAELARLEAELERLEAR 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1097 RDGLRRELLEAQRKGRDSQDSSEAH-RQEASELRRSLSEGAKEREALrrsNEELRSAVKKAESERISLKLANEDKEQKLA 1175
Cdd:COG4913   318 LDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARL---EALLAALGLPLPASAEEFAALRAEAAALLE 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1176 LLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLA-----LGE----RTEKE 1246
Cdd:COG4913   395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEaelpfVGElievRPEEE 474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1247 SRREAL-----GLRQRLL------------------KGESSLEALKQELQGSQR----------KLQEQEAEFRARERGL 1293
Cdd:COG4913   475 RWRGAIervlgGFALTLLvppehyaaalrwvnrlhlRGRLVYERVRTGLPDPERprldpdslagKLDFKPHPFRAWLEAE 554

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1294 LG---------SLEEARGAEKRLL------DSARSLELRLEAVRAETSELGL----RLSAAEGRAQGLEVELARVEAQRR 1354
Cdd:COG4913   555 LGrrfdyvcvdSPEELRRHPRAITragqvkGNGTRHEKDDRRRIRSRYVLGFdnraKLAALEAELAELEEELAEAEERLE 634

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1355 VAEAQLGGLRSALRRGLGLGRVSSSPAREAPAggsgdglsspspleysprsqppspgliaspappdldpEAVRDALRDFL 1434
Cdd:COG4913   635 ALEAELDALQERREALQRLAEYSWDEIDVASA-------------------------------------EREIAELEAEL 677

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1435 QELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQE----ESVRRS 1510
Cdd:COG4913   678 ERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELrallEERFAA 757

                         570       580       590
                  ....*....|....*....|....*....|..
gi 568931102 1511 KRECRATLDQMAVLERSLQATESELRASQEKV 1542
Cdd:COG4913   758 ALGDAVERELRENLEERIDALRARLNRAEEEL 789
46 PHA02562
endonuclease subunit; Provisional
 1019-1191 5.18e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 5.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1019 MERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRD 1098
Cdd:PHA02562  204 IEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEK 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1099 G-------------------LRRELLEAQRKGRDSQDSSEAHRQ---EASELRRSLSEGAKEREALRRSNEELRSAVKKA 1156
Cdd:PHA02562  284 GgvcptctqqisegpdritkIKDKLKELQHSLEKLDTAIDELEEimdEFNEQSKKLLELKNKISTNKQSLITLVDKAKKV 363

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568931102 1157 ESERISLKLANEDKEQKLALLEEARVSVAKEAGEL 1191
Cdd:PHA02562  364 KAAIEELQAEFVDNAEELAKLQDELDKIVKTKSEL 398
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
825-1027 5.38e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 5.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  825 EAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAAldkELMTQKLVQAE 904
Cdd:COG3206   192 EEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALP---ELLQSPVIQQL 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  905 REAQASLREQRAaheeDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERD--EGLLL 982
Cdd:COG3206   269 RAQLAELEAELA----ELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAqlEARLA 344

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 568931102  983 AESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQ 1027
Cdd:COG3206   345 ELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1411-1794 5.47e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 5.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1411 GLIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSAD 1490
Cdd:PRK02224  297 DLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAR 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1491 RRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRS 1570
Cdd:PRK02224  377 EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPE 456

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1571 IKLELQRRALEGELQRSRlglgdreahaqalqDRVDSLQRQVADSEVKAGTLQLTVERLSgALAKVEESEGNLRSKVQSL 1650
Cdd:PRK02224  457 CGQPVEGSPHVETIEEDR--------------ERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDL 521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1651 TDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQ 1730
Cdd:PRK02224  522 EELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAI 601

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568931102 1731 LQQLQQALRQRQEGEAMAlrsvqKLQEERRllqERLGSLQRALAQLEAEKRDLERSALQFDKDR 1794
Cdd:PRK02224  602 ADAEDEIERLREKREALA-----ELNDERR---ERLAEKRERKRELEAEFDEARIEEAREDKER 657
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 73-588 5.71e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.96  E-value: 5.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102    73 RRQLQEEQSSYRRKLQAYQEGQQRQAQLVQRLQAKILQYKKQCSELEKQLMDRSteleqQRLRDTEHSQDLDSALLRLEE 152
Cdd:TIGR00606  572 KKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE-----DKLFDVCGSQDEESDLERLKE 646

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   153 EQQRS----ASLAQVNAMLREQLDQANLANQA---LSEDIRKVTSDWTRSCKELEQREAVWRREEESFntyfSSEHSRLL 225
Cdd:TIGR00606  647 EIEKSskqrAMLAGATAVYSQFITQLTDENQSccpVCQRVFQTEAELQEFISDLQSKLRLAPDKLKST----ESELKKKE 722

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   226 RLWRQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELGLGLSASLHRAES-KAEAALEKQKLLQAQLEEQLQAKLL 304
Cdd:TIGR00606  723 KRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTiMPEEESAKVCLTDVTIMERFQMELK 802

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   305 R-EKDLAQLQVQSDldkadlsarVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQttldtEDGEGLQQTLRD 383
Cdd:TIGR00606  803 DvERKIAQQAAKLQ---------GSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQ-----EQIQHLKSKTNE 868

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   384 LAQAALSDTESGVQLSSSERTADTSDGSL----RGFSGQRTPTPPRHSPGRGRSPRRGLSPACSDSST------------ 447
Cdd:TIGR00606  869 LKSEKLQIGTNLQRRQQFEEQLVELSTEVqsliREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNkkaqdkvndike 948

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   448 -LTLIHSALHKRQLQVQDMRGRYEASQEL-LGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSAN 525
Cdd:TIGR00606  949 kVKNIHGYMKDIENKIQDGKDDYLKQKETeLNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKREN 1028

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568931102   526 ELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARREL 588
Cdd:TIGR00606 1029 ELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKEL 1091
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 543-862 6.00e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 6.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   543 QQQAKELRQELEKLQAAQEEL------KRQHNQLEDAQEDSVQEGARARRELER--SHRQLEQLEVKRSGLTKELVEVRE 614
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKareverRRKLEEAEKARQAEMDRQAAIYAEQERmaMERERELERIRQEERKRELERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   615 AlSCAILQRDVLQTEKAEVaEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKV 694
Cdd:pfam17380  368 E-EIAMEISRMRELERLQM-ERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   695 ALLGRQQQAEhattmaVEKQELLEQLRLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRD 774
Cdd:pfam17380  446 REMERVRLEE------QERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLE 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   775 QELEQ---ALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREgrtlseeairlRLEKEALESSLFdvqRQLAQLE 851
Cdd:pfam17380  520 KEMEErqkAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERS-----------RLEAMEREREMM---RQIVESE 585

                          330
                   ....*....|.
gi 568931102   852 ARREQLEADSQ 862
Cdd:pfam17380  586 KARAEYEATTP 596
PRK12704 PRK12704
phosphodiesterase; Provisional
 886-1004 6.60e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 6.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  886 EEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQeREELLARmeaEKEEL 965
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQ-KEENLDR---KLELL 105

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 568931102  966 SKEIAALQQERDEglllaESEKQQALSLKESEKTALSEK 1004
Cdd:PRK12704  106 EKREEELEKKEKE-----LEQKQQELEKKEEELEELIEE 139
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 746-1137 7.37e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 41.20  E-value: 7.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   746 EQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQAlrESQRQVEALERAAREKEAMAKER-AGLAVKLAAAEREGRTL-- 822
Cdd:pfam13166   95 QEKIAKLKKEIKDHEEKLDAAEANLQKLDKEKEKL--EADFLDECWKKIKRKKNSALSEAlNGFKYEANFKSRLLREIek 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   823 --SEEAIRLRLEK-EALESSLFDVQRQ-LAQLEARREQLEA-DSQALLLAKetltgelaglrqQVTSTEEKAALDKELMT 897
Cdd:pfam13166  173 dnFNAGVLLSDEDrKAALATVFSDNKPeIAPLTFNVIDFDAlEKAEILIQK------------VIGKSSAIEELIKNPDL 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   898 QKLVQA---------------EREAQASLREQRAAH-----EEDLQRLQHEKEAAWRELQAERAQLQG-----QLQQERE 952
Cdd:pfam13166  241 ADWVEQglelhkahldtcpfcGQPLPAERKAALEAHfddefTEFQNRLQKLIEKVESAISSLLAQLPAvsdlaSLLSAFE 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   953 ELLARMEAEKEELSKEIAALQQErdegllLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQ 1032
Cdd:pfam13166  321 LDVEDIESEAEVLNSQLDGLRRA------LEAKRKDPFKSIELDSVDAKIESINDLVASINELIAKHNEITDNFEEEKNK 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  1033 DRNTLNA-LTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRElLEAQRKG 1111
Cdd:pfam13166  395 AKKKLRLhLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIKELEAQLRDHKPGADEINKL-LKAFGFG 473

                          410       420       430
                   ....*....|....*....|....*....|..
gi 568931102  1112 RDSQDSSEA------HRQEASELRRSLSEGAK 1137
Cdd:pfam13166  474 ELELSFNEEgkgyriIRKGGSQAAETLSEGER 505
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1024-1349 8.05e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 8.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1024 RDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLgrqrEACMREAEELRTQLRVLEDTRDGLRRE 1103
Cdd:COG4372    41 DKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQL----QAAQAELAQAQEELESLQEEAEELQEE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1104 LLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVS 1183
Cdd:COG4372   117 LEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNA 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1184 VAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGES 1263
Cdd:COG4372   197 EKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEE 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1264 SLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLE 1343
Cdd:COG4372   277 ELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVL 356


                  ....*.
gi 568931102 1344 VELARV 1349
Cdd:COG4372   357 ELLSKG 362
PTZ00491 PTZ00491
major vault protein; Provisional
 896-1049 8.15e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 41.16  E-value: 8.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  896 MTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEA-----AWRELQAERAQLQGQlQQEREELLARMEAEKEElskeia 970
Cdd:PTZ00491  659 ITTKSQEAAARHQAELLEQEARGRLERQKMHDKAKAeeqrtKLLELQAESAAVESS-GQSRAEALAEAEARLIE------ 731

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  971 alqqerdeglllAESEKQQAlslkesEKTALSEKLMgtrhslAAISLEMERQKRDAQSRQEQDRNTLN-ALTSELRDLRA 1049
Cdd:PTZ00491  732 ------------AEAEVEQA------ELRAKALRIE------AEAELEKLRKRQELELEYEQAQNELEiAKAKELADIEA 787
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
898-1396 8.92e-03

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 41.13  E-value: 8.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  898 QKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERD 977
Cdd:COG5281     2 AALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102  978 EGLLLAESEKQQALSLKESEKTALSEKLMGTRhSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAA 1057
Cdd:COG5281    82 AALAEDAAAAAAAAEAALAALAAAALALAAAA-LAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1058 HAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAK 1137
Cdd:COG5281   161 AAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1138 EREALRRSNEELRSAVKKAESERislKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMK 1217
Cdd:COG5281   241 SAAAQALAALAAAAAAAALALAA---AAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAA 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1218 TLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSL 1297
Cdd:COG5281   318 AAAAQALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSAT 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1298 EEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGLGRVS 1377
Cdd:COG5281   398 NVAAQVAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIADALANAALASAADALGGALAGALGGLFGGGGGAAAGA 477

                         490
                  ....*....|....*....
gi 568931102 1378 SSPAREAPAGGSGDGLSSP 1396
Cdd:COG5281   478 AVYAGALGPFASGGVVSGP 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1193-1369 9.60e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 9.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1193 ASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQEL 1272
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102 1273 QGSQRKLQEQEAEF----RARERGLLGSLEEARGAEKRLL---DSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVE 1345
Cdd:COG4942   100 EAQKEELAELLRALyrlgRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180
                  ....*....|....*....|....
gi 568931102 1346 LARVEAQRRVAEAQLGGLRSALRR 1369
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLAR 203
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 478-770 9.89e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.77  E-value: 9.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   478 SVRKQLSDSEGERRGLEEQLQRLRDQTaasaqaqEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQ 557
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEI-------EKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ 418

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   558 AAQEELKRQH-------------------------------NQLEDAQEDSVQEGAR----ARRELERSHRQLEQLEVKR 602
Cdd:TIGR04523  419 QEKELLEKEIerlketiiknnseikdltnqdsvkeliiknlDNTRESLETQLKVLSRsinkIKQNLEQKQKELKSKEKEL 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   603 SGLTKELVEVREalscailQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKmsalnESLAQDKLEL 682
Cdd:TIGR04523  499 KKLNEEKKELEE-------KVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKK-----ENLEKEIDEK 566

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568931102   683 NRLIAQLEEEKVALLGRQQQA-EHATTMAVEKQELLEQLrLEQEVERQGLQGSLCVAEQAREALEQQILVLRSERSHLQE 761
Cdd:TIGR04523  567 NKEIEELKQTQKSLKKKQEEKqELIDQKEKEKKDLIKEI-EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645


                   ....*....
gi 568931102   762 QLAQLSRQL 770
Cdd:TIGR04523  646 EVKQIKETI 654
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH