|
Name |
Accession |
Description |
Interval |
E-value |
| CCDC144C |
pfam14915 |
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ... |
853-1156 |
4.07e-152 |
|
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ankyrin repeat domain-containing protein 26-like 1 found in eukaryotes. Its function remains unknown, however, it is known to contain a coiled-coil domain which corresponds to this region. The ankyrin repeat which features in this protein is a common amino acid motif.
Pssm-ID: 464371 [Multi-domain] Cd Length: 304 Bit Score: 466.77 E-value: 4.07e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 853 NQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLD 932
Cdd:pfam14915 1 NCMLQDEIAMLRLEIDTIKNQNQEKEKKYLEDIEILKEKNDDLQKTLKLNEETLTKTVFQYNGQLNVLKAENTMLNSKLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 933 NEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKL 1012
Cdd:pfam14915 81 NEKQNKERLETEVESYRSRLAAAIQDHEQSQTSKRDLELAFQRERDEWLRLQDKMNFDVSNLRDENEILSQQLSKAESKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1013 NSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDA 1092
Cdd:pfam14915 161 NSLENELHRTRDALREKTLLLESVQRDLSQAQCQKKELEHMYQNEQDKVNKYIGKQESLEERLAQLQSENMLLRQQLEDA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941652 1093 ANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAER 1156
Cdd:pfam14915 241 QNKADAKEKTVIDIQDQFQDIVKKLQAESEKQVLLLEERNKELINECNHLKERLYQYEKEKAER 304
|
|
| DUF3496 |
pfam12001 |
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. ... |
1462-1569 |
2.09e-51 |
|
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 110 amino acids in length.
Pssm-ID: 463425 [Multi-domain] Cd Length: 109 Bit Score: 176.39 E-value: 2.09e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1462 RSQMELRIKDLESQLYRMKA-QEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNRSLLSTLS 1540
Cdd:pfam12001 1 RSQMELRIKDLESELSKMKTsQEDSNKIELEKYKQLYLEELKVRKSLSNKLNKTNERLAEVSTKLLVEKQQNRSLLSTLT 80
|
90 100
....*....|....*....|....*....
gi 568941652 1541 TRPVVECPCVGSFHNSLVFNRTLIPRENI 1569
Cdd:pfam12001 81 TRPVLESPCVGNLNNSLVLNRNFIPRENL 109
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
51-219 |
3.10e-40 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 151.26 E-value: 3.10e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:COG0666 91 LHAAARNGDLEIVKLLLEAGAD-VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIV 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVD 210
Cdd:COG0666 170 KLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKD 249
|
....*....
gi 568941652 211 QLGSNRQMF 219
Cdd:COG0666 250 KDGLTALLL 258
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
42-213 |
1.06e-39 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 149.72 E-value: 1.06e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 42 HIHDKDMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKA 121
Cdd:COG0666 48 ALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 122 VQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVK 201
Cdd:COG0666 128 AYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLE 207
|
170
....*....|..
gi 568941652 202 KKASIHAVDQLG 213
Cdd:COG0666 208 AGADVNAKDNDG 219
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
51-215 |
1.52e-32 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 128.92 E-value: 1.52e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:COG0666 124 LHLAAYNGNLEIVKLLLEAGAD-VNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVD 210
Cdd:COG0666 203 KLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAAL 282
|
....*
gi 568941652 211 QLGSN 215
Cdd:COG0666 283 LDLLT 287
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
43-213 |
7.11e-30 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 121.21 E-value: 7.11e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 43 IHDKDMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAV 122
Cdd:COG0666 16 LLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 123 QCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKK 202
Cdd:COG0666 96 RNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEA 175
|
170
....*....|.
gi 568941652 203 KASIHAVDQLG 213
Cdd:COG0666 176 GADVNARDNDG 186
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
679-1526 |
2.75e-23 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 108.22 E-value: 2.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 679 ELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRK 758
Cdd:TIGR02168 221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 759 GEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNarmlqdgilashLCKQKEIEMTQKKMTSE 838
Cdd:TIGR02168 301 EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE------------ELESLEAELEELEAELE 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 839 VSVSHEKEKDLLHknQRLQDEVAVLRLEMDTIKSHNQEKEKRyledIKIANEKNDNLQRMVKLNEETFTKTIFQYT-GQL 917
Cdd:TIGR02168 369 ELESRLEELEEQL--ETLRSKVAQLELQIASLNNEIERLEAR----LERLEDRRERLQQEIEELLKKLEEAELKELqAEL 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 918 NSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMN--FDMSNLR 995
Cdd:TIGR02168 443 EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKnqSGLSGIL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 996 DnneVLSQQLSKTERKLNSLEIefhhtkdelrektlAL-KHAQRDLSQT-QCQMKEVEHMFQDEQGKVSKFMGKQesieE 1073
Cdd:TIGR02168 523 G---VLSELISVDEGYEAAIEA--------------ALgGRLQAVVVENlNAAKKAIAFLKQNELGRVTFLPLDS----I 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1074 RLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRF-------QAESQRHSLRLEDRnqeLVSECSHLRERL 1146
Cdd:TIGR02168 582 KGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldNALELAKKLRPGYR---IVTLDGDLVRPG 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1147 CQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKM 1226
Cdd:TIGR02168 659 GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1227 EDHLQKLELEKSKFEITIKKQSEEIDQLQENLsrvnlsEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVL 1306
Cdd:TIGR02168 739 EAEVEQLEERIAQLSKELTELEAEIEELEERL------EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL 812
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1307 KMTKKELNEYENRELNLRQDIknnhlemdipvSTLIKKIDDLTAKLETASskcLHLGKKNQLLQQELLLMRTIQKKCGKL 1386
Cdd:TIGR02168 813 TLLNEEAANLRERLESLERRI-----------AATERRLEDLEEQIEELS---EDIESLAAEIEELEELIEELESELEAL 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1387 EKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREvEERARQDLVEKLKQVNLFLQ-AQAASQESLEQLRENSNASVRSQM 1465
Cdd:TIGR02168 879 LNERASLEEALALLRSELEELSEELRELESKRSE-LRRELEELREKLAQLELRLEgLEVRIDNLQERLSEEYSLTLEEAE 957
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941652 1466 ELRIKDLESQlyrMKAQEDFDKIElEKYKQL------YQEEFRARKSLSSKLNKTSEKLEEASSKLL 1526
Cdd:TIGR02168 958 ALENKIEDDE---EEARRRLKRLE-NKIKELgpvnlaAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
85-177 |
8.89e-21 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.25 E-value: 8.89e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 85 LHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHgADPNvMDSSGNTALHYAVYSENTSMAA 164
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVN-LKDNGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 568941652 165 KLLAHNANIEAKN 177
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
675-1333 |
2.06e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 95.51 E-value: 2.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 675 KRLIELKRShCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSAD---QLSEKT 751
Cdd:TIGR02168 330 SKLDELAEE-LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNneiERLEAR 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 752 SEQLRRKGEQCQSEVEA--RQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQN----ARMLQDGILASHLCKQ 825
Cdd:TIGR02168 409 LERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREeleeAEQALDAAERELAQLQ 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 826 KEIEMTQKkMTSEVSVSHEKEKDLLHKNQRLQDEV------------------AVLRLEMDTIKSHNQEKEKRylediKI 887
Cdd:TIGR02168 489 ARLDSLER-LQENLEGFSEGVKALLKNQSGLSGILgvlselisvdegyeaaieAALGGRLQAVVVENLNAAKK-----AI 562
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 888 ANEKNDNLQRMVKLNEETFTKTIFQYTGqLNSLKAENTMLSSKLDNEKQnKERLETDVESFRSR------LASALHDHAE 961
Cdd:TIGR02168 563 AFLKQNELGRVTFLPLDSIKGTEIQGND-REILKNIEGFLGVAKDLVKF-DPKLRKALSYLLGGvlvvddLDNALELAKK 640
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 962 IQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEV--LSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRD 1039
Cdd:TIGR02168 641 LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIeeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1040 LSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQA 1119
Cdd:TIGR02168 721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1120 ESQRHSlRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLK 1199
Cdd:TIGR02168 801 LREALD-ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL 879
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1200 KKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLE-------LEKSKFEITIKKQSEEIDQLQENLS-RVNLSEEDKEKL 1271
Cdd:TIGR02168 880 NERASLEEALALLRSELEELSEELRELESKRSELRreleelrEKLAQLELRLEGLEVRIDNLQERLSeEYSLTLEEAEAL 959
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941652 1272 QKLTELKEslectvDQEQKRSSALEKELAEFKEVLKMTkkeLNEYEnrELNLRQDIKNNHLE 1333
Cdd:TIGR02168 960 ENKIEDDE------EEARRRLKRLENKIKELGPVNLAA---IEEYE--ELKERYDFLTAQKE 1010
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
51-184 |
3.99e-19 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 89.63 E-value: 3.99e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 51 IHKAASVGDVAKVQhILIlgKSG--VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEE 128
Cdd:COG0666 157 LHLAAANGNLEIVK-LLL--EAGadVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLE 233
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 568941652 129 CAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPM 184
Cdd:COG0666 234 IVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
51-144 |
1.80e-18 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 81.70 E-value: 1.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 51 IHKAASVGDVAKVQHILILGkSGVNDRDKKDRTALHLACAYGHPEVVTLLVErKCEIDARDsESSTALIKAVQCQEEECA 130
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENG-ADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIV 77
|
90
....*....|....
gi 568941652 131 AILLDHGADPNVMD 144
Cdd:pfam12796 78 KLLLEKGADINVKD 91
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
66-213 |
2.37e-17 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 84.62 E-value: 2.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 66 ILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDS 145
Cdd:COG0666 6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 146 SGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
Cdd:COG0666 86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDG 153
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
662-1353 |
1.94e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 85.88 E-value: 1.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 662 ASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKR 741
Cdd:TIGR02168 267 EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 742 RSADQLSEKTSEQLrrkgeqcQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSR---------EQNARM 812
Cdd:TIGR02168 347 EELKEELESLEAEL-------EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlearlerleDRRERL 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 813 LQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRL---QDEVAVLRLEMDTIKSHNQEKEKRY--LEDIKI 887
Cdd:TIGR02168 420 QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALeelREELEEAEQALDAAERELAQLQARLdsLERLQE 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 888 ANEKNDNLQRMVKLNEETFTktifQYTGQLNSL--------KAENTMLSSKL-----DNEKQNKERLETDVESFRSR--- 951
Cdd:TIGR02168 500 NLEGFSEGVKALLKNQSGLS----GILGVLSELisvdegyeAAIEAALGGRLqavvvENLNAAKKAIAFLKQNELGRvtf 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 952 LASALHDHAEIQTAKRDL---EIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTE-RKLNSLEIEFHHTKDEL- 1026
Cdd:TIGR02168 576 LPLDSIKGTEIQGNDREIlknIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElAKKLRPGYRIVTLDGDLv 655
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1027 -REKTLALKHAQRDLSqTQCQMKEVEHMfqdeQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVN 1105
Cdd:TIGR02168 656 rPGGVITGGSAKTNSS-ILERRREIEEL----EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1106 IQDQFQDVLTRFQAESQRHSlRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLK-KQSMSEASLEVS 1184
Cdd:TIGR02168 731 LRKDLARLEAEVEQLEERIA-QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEeLKALREALDELR 809
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1185 SRYRsNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQenlsrvNLS 1264
Cdd:TIGR02168 810 AELT-LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL------NER 882
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1265 EEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNH-LEMDIPVsTLIK 1343
Cdd:TIGR02168 883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYsLTLEEAE-ALEN 961
|
730
....*....|
gi 568941652 1344 KIDDLTAKLE 1353
Cdd:TIGR02168 962 KIEDDEEEAR 971
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1023-1533 |
8.53e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.45 E-value: 8.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1023 KDELREKTLALKHAQRDLSQTQCQMKEVEHmfQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKT 1102
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAEL--EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1103 IVNIQDQFQDVLTRFQAESQRhSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLE 1182
Cdd:COG1196 297 LARLEQDIARLEERRRELEER-LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1183 VSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvn 1262
Cdd:COG1196 376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-- 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1263 LSEEDKEKLQKLTELKESLEctvdQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELN-LRQDIKNNHLEMDIPVSTL 1341
Cdd:COG1196 454 LEEEEEALLELLAELLEEAA----LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVL 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1342 IKKIDDLTAKLETASS---------------KCLHLGKKNQLLQQELLLMRTIQkkcgKLEKNKKQLEQEVVNLRSHMEK 1406
Cdd:COG1196 530 IGVEAAYEAALEAALAaalqnivveddevaaAAIEYLKAAKAGRATFLPLDKIR----ARAALAAALARGAIGAAVDLVA 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1407 NMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQLYRMKAQEDFD 1486
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 568941652 1487 KIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNR 1533
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
995-1358 |
1.16e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 79.72 E-value: 1.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 995 RDNNEVLSQQLSKTERKLNSLE------IEFHHTKDELREKTLAL-----KHAQRDLSQTQCQMKEVEHMFQDEQGKVSK 1063
Cdd:TIGR02168 185 RENLDRLEDILNELERQLKSLErqaekaERYKELKAELRELELALlvlrlEELREELEELQEELKEAEEELEELTAELQE 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1064 FMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQdvltrfqaesqrhslRLEDRNQELVSECSHLR 1143
Cdd:TIGR02168 265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA---------------NLERQLEELEAQLEELE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1144 ERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREavhha 1223
Cdd:TIGR02168 330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER----- 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1224 ekMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEklqkLTELKESLECTVDQEqkrsSALEKELAEFK 1303
Cdd:TIGR02168 405 --LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE----LEELQEELERLEEAL----EELREELEEAE 474
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 568941652 1304 EVLKMTKKELNEYENReLNLRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSK 1358
Cdd:TIGR02168 475 QALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
41-210 |
1.19e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 78.53 E-value: 1.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 41 YHIHDKDMGKIHKAASVGDVAKVQHILILGkSGVNDRDKKDRTALHLACAYGHP---EVVTLLVERKCEIDARDSESSTA 117
Cdd:PHA03095 8 DIIMEAALYDYLLNASNVTVEEVRRLLAAG-ADVNFRGEYGKTPLHLYLHYSSEkvkDIVRLLLEAGADVNAPERCGFTP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 118 LIKAVQCQ-EEECAAILLDHGADPNVMDSSGNTALHyaVY----SENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENK 192
Cdd:PHA03095 87 LHLYLYNAtTLDVIKLLIKAGADVNAKDKVGRTPLH--VYlsgfNINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRN 164
|
170 180
....*....|....*....|
gi 568941652 193 QHI--VEFLVKKKASIHAVD 210
Cdd:PHA03095 165 ANVelLRLLIDAGADVYAVD 184
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
51-204 |
2.22e-14 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 77.34 E-value: 2.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 51 IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:PHA02875 72 LHDAVEEGDVKAVEELLDLGKFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGI 151
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568941652 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKD-DLTPMLLAVKENKQHIVEFLVKKKA 204
Cdd:PHA02875 152 ELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNgCVAALCYAIENNKIDIVRLFIKRGA 226
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
707-1211 |
8.37e-14 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 77.14 E-value: 8.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 707 SETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTV 786
Cdd:pfam01576 57 AEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKL 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 787 KSHLNqVLEERNEtqrQLSREQNARMLQDGILASHLCKQKE--IEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLR 864
Cdd:pfam01576 137 EEDIL-LLEDQNS---KLSKERKLLEERISEFTSNLAEEEEkaKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRK 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 865 LEMDTIKSHNQEKE-KRYLEDIKIAN-EKNDNLQR-MVKLNEETFTKTIFQytGQLNSLKAENTMLSSKLDNEKQNKER- 940
Cdd:pfam01576 213 LEGESTDLQEQIAElQAQIAELRAQLaKKEEELQAaLARLEEETAQKNNAL--KKIRELEAQISELQEDLESERAARNKa 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 941 ------LETDVESFRSRLASALHDHAEIQT--AKRDLEIA-FQRARDEWFRVKDKMNFDMSNLRDNN-EVLSQQLSKTER 1010
Cdd:pfam01576 291 ekqrrdLGEELEALKTELEDTLDTTAAQQElrSKREQEVTeLKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKR 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1011 KLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLD 1090
Cdd:pfam01576 371 NKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLN 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1091 DAANKAESKDKTIVNIQDQFQDVLTRFQAESqRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADT 1170
Cdd:pfam01576 451 EAEGKNIKLSKDVSSLESQLQDTQELLQEET-RQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDM 529
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 568941652 1171 LKKQSMSEASLEVssryrsnLEEEARDLKKKLGQLRSQLQE 1211
Cdd:pfam01576 530 KKKLEEDAGTLEA-------LEEGKKRLQRELEALTQQLEE 563
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
66-226 |
8.68e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 75.83 E-value: 8.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 66 ILILGKSGVNDRDKKDRTALHLACAYGHP--EVVTLLVERKCEIDARDSESSTAL-IKAVQCQeeeCAAI----LLDHGA 138
Cdd:PHA03095 172 LLIDAGADVYAVDDRFRSLLHHHLQSFKPraRIVRELIRAGCDPAATDMLGNTPLhSMATGSS---CKRSlvlpLLIAGI 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 139 DPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAV----DQLGS 214
Cdd:PHA03095 249 SINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAETVaatlNTASV 328
|
170
....*....|..
gi 568941652 215 NRQMFEYDGKRL 226
Cdd:PHA03095 329 AGGDIPSDATRL 340
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
674-1301 |
3.86e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 3.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 674 YKRL-IELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTS 752
Cdd:COG1196 215 YRELkEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 753 EQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLqdgilashlcKQKEIEMTQ 832
Cdd:COG1196 295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE----------AEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 833 KKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEEtftktifq 912
Cdd:COG1196 365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE-------- 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 913 ytgqlnsLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEwfrvkdkmnfdmS 992
Cdd:COG1196 437 -------EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL------------L 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 993 NLRDNNEVLSQQLSKTERKLNSLEIefHHTKDELREKTLALKHAQRDLSQTQCQMKEVEhmfQDEQGKvskfmgkqESIE 1072
Cdd:COG1196 498 EAEADYEGFLEGVKAALLLAGLRGL--AGAVAVLIGVEAAYEAALEAALAAALQNIVVE---DDEVAA--------AAIE 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1073 ERLAQLQSENTLLrqqlddAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENE 1152
Cdd:COG1196 565 YLKAAKAGRATFL------PLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1153 KAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQK 1232
Cdd:COG1196 639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941652 1233 LELEKSKFEITIKKQSEEIDQLQEnlsrvnlsEEDKEKLQKLTELKESLEcTVDQEQKRSSALEKELAE 1301
Cdd:COG1196 719 EELEEEALEEQLEAEREELLEELL--------EEEELLEEEALEELPEPP-DLEELERELERLEREIEA 778
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1060-1427 |
5.04e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 74.33 E-value: 5.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1060 KVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKtivniqdqFQDVLTRFQaesqrhslrlEDRNQELVSEC 1139
Cdd:TIGR02169 171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------YQALLKEKR----------EYEGYELLKEK 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1140 SHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASL-EVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHRE 1218
Cdd:TIGR02169 233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLeELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1219 AVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDqlQENLSRVNLSEEDKEKLQKLTELKESLEctvdQEQKRSSALEKE 1298
Cdd:TIGR02169 313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIE--EERKRRDKLTEEYAELKEELEDLRAELE----EVDKEFAETRDE 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1299 LAEFKEVLKMTKKELNEYENRELNL-----RQDIKNNHLEMDIPVstLIKKIDDLTAKLETASSKclhlgkknqllqqel 1373
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLqeelqRLSEELADLNAAIAG--IEAKINELEEEKEDKALE--------------- 449
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 568941652 1374 llmrtIQKKCGKLEKNKKQL---EQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQ 1427
Cdd:TIGR02169 450 -----IKKQEWKLEQLAADLskyEQELYDLKEEYDRVEKELSKLQRELAEAEAQARA 501
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
62-210 |
5.21e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 73.16 E-value: 5.21e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 62 KVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTAL-----IKAVQCQEEECAAILLDH 136
Cdd:PHA03100 16 KNIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLhylsnIKYNLTDVKEIVKLLLEY 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 137 GADPNVMDSSGNTALHYAVY--SENTSMAAKLLAHNANIEAKNKDDLTPMLLAVK--ENKQHIVEFLVKKKASIHAVD 210
Cdd:PHA03100 96 GANVNAPDNNGITPLLYAISkkSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLEsnKIDLKILKLLIDKGVDINAKN 173
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
691-1528 |
1.10e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 73.56 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 691 KLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEAR- 769
Cdd:TIGR02169 217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKi 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 770 QQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSReqnarmlqdgilashlcKQKEIEMTQKKMTSEvsvshEKEKDl 849
Cdd:TIGR02169 297 GELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK-----------------LLAEIEELEREIEEE-----RKRRD- 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 850 lhknqRLQDEVAVLRLEMDTIKSHNQEKEKRYlediKIANEKNDNLQrmvklneetftKTIFQYTGQLNSLKAEntmlss 929
Cdd:TIGR02169 354 -----KLTEEYAELKEELEDLRAELEEVDKEF----AETRDELKDYR-----------EKLEKLKREINELKRE------ 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 930 kLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMnfdmsnlrdnnEVLSQQLSKTE 1009
Cdd:TIGR02169 408 -LDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADL-----------SKYEQELYDLK 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1010 RKLNSLEIEFHhtkdELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEER--------------- 1074
Cdd:TIGR02169 476 EEYDRVEKELS----KLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnn 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1075 -------------------------------LAQLQSENTLLRQQ--LDDAANKAESKDKTIVNIQDQFQDVLTRFQAES 1121
Cdd:TIGR02169 552 vvveddavakeaiellkrrkagratflplnkMRDERRDLSILSEDgvIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEA 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1122 QRH---SLRLEDRNQELVSECSHL----RERLCQYENEKAEREVVvrqlqQELADTLKKQSMSEASLEVSSRYRSNLEEE 1194
Cdd:TIGR02169 632 ARRlmgKYRMVTLEGELFEKSGAMtggsRAPRGGILFSRSEPAEL-----QRLRERLEGLKRELSSLQSELRRIENRLDE 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1195 AR----DLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEED--- 1267
Cdd:TIGR02169 707 LSqelsDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlea 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1268 ---KEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDipvsTLIKK 1344
Cdd:TIGR02169 787 rlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE----NLNGK 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1345 IDDLTAKLETASSKCLHLGKKNQLLQQELLLMrtiQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEER 1424
Cdd:TIGR02169 863 KEELEEELEELEAALRDLESRLGDLKKERDEL---EAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1425 ARQDL--------VEKLKQVNLFLQAQAASQESLEQLRENSNASVrsqmELRIKDLESQLYRMKAQEDFDKIELEKYKQL 1496
Cdd:TIGR02169 940 KGEDEeipeeelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV----LKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
|
890 900 910
....*....|....*....|....*....|...
gi 568941652 1497 YQEEF-RARKSLSSKLNKTSEKLEEASSKLLLE 1528
Cdd:TIGR02169 1016 KREVFmEAFEAINENFNEIFAELSGGTGELILE 1048
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
733-1304 |
4.35e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.51 E-value: 4.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 733 ALKQEEEKR---------RSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQ 803
Cdd:COG1196 217 ELKEELKELeaellllklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 804 LSREQNARMLQDGilashlcKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLE 883
Cdd:COG1196 297 LARLEQDIARLEE-------RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 884 DIKIANEKNDNLQRmvklneetFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQ 963
Cdd:COG1196 370 AEAELAEAEEELEE--------LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 964 TAKRDLEIAFQRARDEwfrvkdkmnfdmsnlRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQT 1043
Cdd:COG1196 442 EALEEAAEEEAELEEE---------------EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1044 QCQMKEVEHmfQDEQGKVSKFMGKQESIEERLAQLQsENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAES-Q 1122
Cdd:COG1196 507 LEGVKAALL--LAGLRGLAGAVAVLIGVEAAYEAAL-EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKiR 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1123 RHSLRLEDRNQELVSECSHLRERLCQYENEKAER---EVVVRQLQQELADTLKKQSMS------EASLEVSSRYRSNLEE 1193
Cdd:COG1196 584 ARAALAAALARGAIGAAVDLVASDLREADARYYVlgdTLLGRTLVAARLEAALRRAVTlagrlrEVTLEGEGGSAGGSLT 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1194 EARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQK 1273
Cdd:COG1196 664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
570 580 590
....*....|....*....|....*....|.
gi 568941652 1274 LTELKESLECTVDQEQKRSSALEKELAEFKE 1304
Cdd:COG1196 744 EEELLEEEALEELPEPPDLEELERELERLER 774
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
994-1474 |
8.75e-12 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 70.45 E-value: 8.75e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 994 LRDNNEVLSQQLSKTERK--------LNSLEIEFHHTKDEL------REKTLALKHAQRDL----SQTQCQMKEVEHMFQ 1055
Cdd:PRK02224 182 LSDQRGSLDQLKAQIEEKeekdlherLNGLESELAELDEEIeryeeqREQARETRDEADEVleehEERREELETLEAEIE 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1056 DEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRF------------------ 1117
Cdd:PRK02224 262 DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDeelrdrleecrvaaqahn 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1118 -QAESQRHS-LRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEA 1195
Cdd:PRK02224 342 eEAESLREDaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1196 RDLKKKLGQLRSQLQEARDQHREA---------------------VHHAEKMEDHLQKLELEKSKFEITI---------- 1244
Cdd:PRK02224 422 DELREREAELEATLRTARERVEEAealleagkcpecgqpvegsphVETIEEDRERVEELEAELEDLEEEVeeveerlera 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1245 ---KKQSEEIDQLQENLSRVN--------LSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKEL 1313
Cdd:PRK02224 502 edlVEAEDRIERLEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1314 NEYENRELNLRQdiknnhlemdipVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTiqkkcgklekNKKQL 1393
Cdd:PRK02224 582 AELKERIESLER------------IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRE----------RKREL 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1394 EQEVVNLRshMEKNMVEHSQAQQYAREVEERARQdLVEKLKQVNLFLQAQAASQESLEQLRENsnasvRSQMELRIKDLE 1473
Cdd:PRK02224 640 EAEFDEAR--IEEAREDKERAEEYLEQVEEKLDE-LREERDDLQAEIGAVENELEELEELRER-----REALENRVEALE 711
|
.
gi 568941652 1474 S 1474
Cdd:PRK02224 712 A 712
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
734-1395 |
1.07e-11 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 70.00 E-value: 1.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 734 LKQEEEKRRSADQLSEKTSEQLRRKGEQcQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNEtQRQLSReqnarml 813
Cdd:TIGR00618 224 LEKELKHLREALQQTQQSHAYLTQKREA-QEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINR-ARKAAP------- 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 814 qdgiLASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKryledIKIANEKnD 893
Cdd:TIGR00618 295 ----LAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIH-----IRDAHEV-A 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 894 NLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAF 973
Cdd:TIGR00618 365 TSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCA 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 974 QRARDEWFRVKDKmNFDMSNLRDNNEVLSQQLSKTE---RKLNSLEIEFHHTKDELREKTLALKHAQRDLSQ-------- 1042
Cdd:TIGR00618 445 AAITCTAQCEKLE-KIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLARLLELQEEPCPLCGSCIHPNParqdidnp 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1043 --TQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAE 1120
Cdd:TIGR00618 524 gpLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKL 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1121 SQ-RHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEV------SSRYRSNLEE 1193
Cdd:TIGR00618 604 SEaEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIrvlpkeLLASRQLALQ 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1194 EARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvnlseEDKEKLQK 1273
Cdd:TIGR00618 684 KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMH-----QARTVLKA 758
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1274 LTELKE--SLECTVD-QEQKRSSALEKELAEFKEVLKMTKKELNEYENRelnLRQDIKNNHLEMDIPVSTLIKKIDDLTA 1350
Cdd:TIGR00618 759 RTEAHFnnNEEVTAAlQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAE---IGQEIPSDEDILNLQCETLVQEEEQFLS 835
|
650 660 670 680
....*....|....*....|....*....|....*....|....*
gi 568941652 1351 KLETASSKclhlgkknqllqqelllMRTIQKKCGKLEKNKKQLEQ 1395
Cdd:TIGR00618 836 RLEEKSAT-----------------LGEITHQLLKYEECSKQLAQ 863
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
826-1353 |
1.19e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.97 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 826 KEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTI-KSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEE 904
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELeLELEEAQAEEYELLAELARLEQDIARLEERRREL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 905 TftktifqytGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVK 984
Cdd:COG1196 315 E---------ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 985 DkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKF 1064
Cdd:COG1196 386 E----ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1065 MGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSEC-SHLR 1143
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYeAALE 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1144 ERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSN---------------LEEEARDLKKKLGQLRSQ 1208
Cdd:COG1196 542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALaaalargaigaavdlVASDLREADARYYVLGDT 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1209 LQEARDQHREAVHHAEKMEDHLQKLE-------------LEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLT 1275
Cdd:COG1196 622 LLGRTLVAARLEAALRRAVTLAGRLRevtlegeggsaggSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 1276 ELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIpvSTLIKKIDDLTAKLE 1353
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL--EELERELERLEREIE 777
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
41-211 |
1.62e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 68.54 E-value: 1.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 41 YHIHDKDMgkihkaASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAY--GHPEVVTLLVERKCEIDARDSESSTAL 118
Cdd:PHA03100 72 LHYLSNIK------YNLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGENLL 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 119 IKAVQC--QEEECAAILLDHGADPNVMDS----------------SGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDD 180
Cdd:PHA03100 146 HLYLESnkIDLKILKLLIDKGVDINAKNRvnyllsygvpinikdvYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYG 225
|
170 180 190
....*....|....*....|....*....|.
gi 568941652 181 LTPMLLAVKENKQHIVEFLVKKKASIHAVDQ 211
Cdd:PHA03100 226 DTPLHIAILNNNKEIFKLLLNNGPSIKTIIE 256
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
688-1327 |
1.80e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.33 E-value: 1.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 688 LTGKLKRM-ENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRS----ADQLSEKTSEQLRRKgEQC 762
Cdd:TIGR02169 277 LNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKllaeIEELEREIEEERKRR-DKL 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 763 QSEVEAR-----------QQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQ-----------NARMLQDGILAS 820
Cdd:TIGR02169 356 TEEYAELkeeledlraelEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQeelqrlseelaDLNAAIAGIEAK 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 821 HL-------CKQKEI-EMTQKKMTSEVSVSHEKEK--DLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANE 890
Cdd:TIGR02169 436 INeleeekeDKALEIkKQEWKLEQLAADLSKYEQElyDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEV 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 891 KNDNLQ-------RMVKLNEETFTKTIFQYTGQLNS---------------LKAEN----TMLS-SKLDNEKQNKERLET 943
Cdd:TIGR02169 516 LKASIQgvhgtvaQLGSVGERYATAIEVAAGNRLNNvvveddavakeaielLKRRKagraTFLPlNKMRDERRDLSILSE 595
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 944 DV------------ESFRSRLASALHDH---AEIQTAKRDLEIA---------FQR--ARDEWFRVKDKMNFDMSNLRDN 997
Cdd:TIGR02169 596 DGvigfavdlvefdPKYEPAFKYVFGDTlvvEDIEAARRLMGKYrmvtlegelFEKsgAMTGGSRAPRGGILFSRSEPAE 675
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 998 NEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQcqmKEVEHMFQDEQgkvsKFMGKQESIEERLAQ 1077
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE---KEIEQLEQEEE----KLKERLEELEEDLSS 748
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1078 LQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTR----FQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEK 1153
Cdd:TIGR02169 749 LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1154 AEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKL 1233
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1234 ELEKSKFEITIKKQSEEIDQLQENLSRVN-------------LSEED-KEKLQKLTELKESLE---CTVDQEQKRSSALE 1296
Cdd:TIGR02169 909 EAQIEKKRKRLSELKAKLEALEEELSEIEdpkgedeeipeeeLSLEDvQAELQRVEEEIRALEpvnMLAIQEYEEVLKRL 988
|
730 740 750
....*....|....*....|....*....|.
gi 568941652 1297 KELAEFKEVLKMTKKELNEYENRELNLRQDI 1327
Cdd:TIGR02169 989 DELKEKRAKLEEERKAILERIEEYEKKKREV 1019
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
54-277 |
1.92e-11 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 69.13 E-value: 1.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 54 AASVGDVAKVQHILILGKSGvNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAIL 133
Cdd:PLN03192 532 VASTGNAALLEELLKAKLDP-DIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRIL 610
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 134 --LDHGADPNvmdsSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAV-- 209
Cdd:PLN03192 611 yhFASISDPH----AAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKAnt 686
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 210 DQLGSNRQMFEYDGKRlQRSENSNPVDNGSEDGSLTRSYNTPGPADSWPTSdeedynFDNKNVPKINL 277
Cdd:PLN03192 687 DDDFSPTELRELLQKR-ELGHSITIVDSVPADEPDLGRDGGSRPGRLQGTS------SDNQCRPRVSI 747
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
757-1482 |
3.18e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 68.66 E-value: 3.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 757 RKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKKMT 836
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 837 SEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQE----------KEKRYLEDIKIANEKNDNLQRMVKLNEEtf 906
Cdd:pfam01576 82 SRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlqlekvtteaKIKKLEEDILLLEDQNSKLSKERKLLEE-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 907 tkTIFQYTGQLnslkAENTMLSSKLDNEKQNKERLETDVEsfrSRLASALHDHAEIQTAKRDLEIAFQRARDEwfrvkdk 986
Cdd:pfam01576 160 --RISEFTSNL----AEEEEKAKSLSKLKNKHEAMISDLE---ERLKKEEKGRQELEKAKRKLEGESTDLQEQ------- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 987 mnfdMSNLRDNNEVLSQQLSKTERKLNSLEiefhhtkDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMG 1066
Cdd:pfam01576 224 ----IAELQAQIAELRAQLAKKEEELQAAL-------ARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEK 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1067 KQESIEERLAQLQSEntlLRQQLDDAANKAESKDKtivniQDQFQDVLTR-FQAESQRHSLRLEDRNQELVSECSHLRER 1145
Cdd:pfam01576 293 QRRDLGEELEALKTE---LEDTLDTTAAQQELRSK-----REQEVTELKKaLEEETRSHEAQLQEMRQKHTQALEELTEQ 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1146 LCQYENEKAEREVVVRQLQQELADTlkkqsmsEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEK 1225
Cdd:pfam01576 365 LEQAKRNKANLEKAKQALESENAEL-------QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSK 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1226 MEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVN--LSEEDKEKLQ------KLTELKESLECTVDQEQKRSSALEK 1297
Cdd:pfam01576 438 LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQelLQEETRQKLNlstrlrQLEDERNSLQEQLEEEEEAKRNVER 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1298 ELAEFKEVLKMTKKELNEYENRELNLRQDIKNnhlemdipvstLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMR 1377
Cdd:pfam01576 518 QLSTLQAQLSDMKKKLEEDAGTLEALEEGKKR-----------LQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLL 586
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1378 TIQKK----CGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVE------ERARQDLVEKLKQVNLFLQAQAASQ 1447
Cdd:pfam01576 587 VDLDHqrqlVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKEtralslARALEEALEAKEELERTNKQLRAEM 666
|
730 740 750
....*....|....*....|....*....|....*
gi 568941652 1448 ESLEQLRENSNASVRsQMELRIKDLESQLYRMKAQ 1482
Cdd:pfam01576 667 EDLVSSKDDVGKNVH-ELERSKRALEQQVEEMKTQ 700
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
74-214 |
4.99e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 66.91 E-value: 4.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 74 VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHY 153
Cdd:PHA02874 117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHN 196
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568941652 154 AVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQhIVEFLVkKKASIHAVDQLGS 214
Cdd:PHA02874 197 AAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNRS-AIELLI-NNASINDQDIDGS 255
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
692-1477 |
5.48e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 67.84 E-value: 5.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 692 LKRMENKYKGLQKEMSETEEVKsrlEHEKVGWEQELCRLRFALKQEEEKRrsaDQLSEktseqLRRKGEQCQSEVeaRQQ 771
Cdd:pfam15921 80 LEEYSHQVKDLQRRLNESNELH---EKQKFYLRQSVIDLQTKLQEMQMER---DAMAD-----IRRRESQSQEDL--RNQ 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 772 LEASLRtlemELKTVKSHLNQVLEERNETQRQLSReqnarmlqdgILASHLCKQKEI--------EMTQKKMTSEVSVSH 843
Cdd:pfam15921 147 LQNTVH----ELEAAKCLKEDMLEDSNTQIEQLRK----------MMLSHEGVLQEIrsilvdfeEASGKKIYEHDSMST 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 844 EKEKDL---LHKNQR-LQDEVAVLR-------LEMDTIKSHNQEKEKRYLEdikianEKNDNLQRMVKLNE---ETFTKT 909
Cdd:pfam15921 213 MHFRSLgsaISKILReLDTEISYLKgrifpveDQLEALKSESQNKIELLLQ------QHQDRIEQLISEHEveiTGLTEK 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 910 IFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHD-----HAEIQTAKRDLEIA---FQRARDEwf 981
Cdd:pfam15921 287 ASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREakrmyEDKIEELEKQLVLAnseLTEARTE-- 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 982 rvKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQ----DE 1057
Cdd:pfam15921 365 --RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKamksEC 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1058 QGKVSKFM----GKQESIEE---RLAQLQSENTLLRQQLDDAANKA---ESKDKTIVNIQDQFQDVLTRFQAESQRHSlR 1127
Cdd:pfam15921 443 QGQMERQMaaiqGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKmtlESSERTVSDLTASLQEKERAIEATNAEIT-K 521
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1128 LEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQEladtlkkqsmsEASLEVssryrsnLEEEARDLKKKLGQlrs 1207
Cdd:pfam15921 522 LRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEK-----------DKVIEI-------LRQQIENMTQLVGQ--- 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1208 qlqEARDQHREAVHHAEkMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLseedkEKLQKLTELKESLECTVDQ 1287
Cdd:pfam15921 581 ---HGRTAGAMQVEKAQ-LEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLEL-----EKVKLVNAGSERLRAVKDI 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1288 EQKRSSALEKelaefkevLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHL-GKKN 1366
Cdd:pfam15921 652 KQERDQLLNE--------VKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMeGSDG 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1367 QLLQQELLLMRTIQKKCGKLE--KNKKQLEQEVV---NLRSHM---EKNMVEH------SQAQQYAREVEERARQDLVEK 1432
Cdd:pfam15921 724 HAMKVAMGMQKQITAKRGQIDalQSKIQFLEEAMtnaNKEKHFlkeEKNKLSQelstvaTEKNKMAGELEVLRSQERRLK 803
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 568941652 1433 LKQVNLFLQAQAASQESLE-----QLRENSNASVRSQMELRIKDLESQLY 1477
Cdd:pfam15921 804 EKVANMEVALDKASLQFAEcqdiiQRQEQESVRLKLQHTLDVKELQGPGY 853
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1067-1525 |
7.37e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 67.40 E-value: 7.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1067 KQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQaesqrhslRLEDRNQELVSECSHLRERL 1146
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREIN--------EISSELPELREELEKLEKEV 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1147 CQYENEKAEREvvvrQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSqLQEARDQHREAVHHAEKM 1226
Cdd:PRK03918 231 KELEELKEEIE----ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYEEY 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1227 EDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVN-LSEEDKEKLQKLTELKESLEC--TVDQEQKRSSALEKELAEfk 1303
Cdd:PRK03918 306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEeLKKKLKELEKRLEELEERHELyeEAKAKKEELERLKKRLTG-- 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1304 EVLKMTKKELNEYENRELNLRQDIKNnHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGK------KNQLLQQELLLMR 1377
Cdd:PRK03918 384 LTPEKLEKELEELEKAKEEIEEEISK-ITARIGELKKEIKELKKAIEELKKAKGKCPVCGRelteehRKELLEEYTAELK 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1378 TIQKKCGKLEKNKKQLEQEVVNLRSHMEK------------------------NMVEHSQAQQYAREVEERARQ------ 1427
Cdd:PRK03918 463 RIEKELKEIEEKERKLRKELRELEKVLKKeseliklkelaeqlkeleeklkkyNLEELEKKAEEYEKLKEKLIKlkgeik 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1428 DLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQLYRMKAQEDFDK--IELEKYKQLYQEEFRARK 1505
Cdd:PRK03918 543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNeyLELKDAEKELEREEKELK 622
|
490 500
....*....|....*....|
gi 568941652 1506 SLSSKLNKTSEKLEEASSKL 1525
Cdd:PRK03918 623 KLEEELDKAFEELAETEKRL 642
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
59-210 |
1.34e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 66.24 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 59 DVAKVQHILILGkSGVNDRDKKDRTALHLACAYG-HPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHG 137
Cdd:PHA02876 320 DTENIRTLIMLG-ADVNAADRLYITPLHQASTLDrNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYG 398
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568941652 138 ADPNVMDSSGNTALHYAVYSENTSMAAK-LLAHNANIEAKNKDDLTPMLLAVKEN-KQHIVEFLVKKKASIHAVD 210
Cdd:PHA02876 399 ADIEALSQKIGTALHFALCGTNPYMSVKtLIDRGANVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAIN 473
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
961-1541 |
1.44e-10 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 66.40 E-value: 1.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 961 EIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRdnnevlsQQLSKTERKLNSLEiEFHHTKDELREKTLALKHAQRDL 1040
Cdd:pfam12128 280 ERQETSAELNQLLRTLDDQWKEKRDELNGELSAAD-------AAVAKDRSELEALE-DQHGAFLDADIETAAADQEQLPS 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1041 SQTQCQMKEVEH-MFQDEQGKVskfmgkQESIEERLAQLQSEN-TLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQ 1118
Cdd:pfam12128 352 WQSELENLEERLkALTGKHQDV------TAKYNRRRSKIKEQNnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELR 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1119 AESQRHSLRLEDRNQELVSECSHLRERL--CQYENE----KAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLE 1192
Cdd:pfam12128 426 EQLEAGKLEFNEEEYRLKSRLGELKLRLnqATATPElllqLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQAS 505
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1193 EEARDLKKKLGQLRSQLQEARDQHREAVH--------HAEKMEDHLQKL---EL------------EKSKFEITIKKQSE 1249
Cdd:pfam12128 506 EALRQASRRLEERQSALDELELQLFPQAGtllhflrkEAPDWEQSIGKVispELlhrtdldpevwdGSVGGELNLYGVKL 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1250 EIDQLQENlSRVNLSEEDKEKLQKLTElkeslecTVDQEQKRSSALEKELAEFKEVLKMTKKELNE----YENRELNLRQ 1325
Cdd:pfam12128 586 DLKRIDVP-EWAASEEELRERLDKAEE-------ALQSAREKQAAAEEQLVQANGELEKASREETFartaLKNARLDLRR 657
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1326 diknnhlemdipvstlikkiddLTAKLETASSKClhlgkknqlLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHME 1405
Cdd:pfam12128 658 ----------------------LFDEKQSEKDKK---------NKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQK 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1406 KNMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQES-LEQLRENSNAS------VRSQMELRIKDLESQLYR 1478
Cdd:pfam12128 707 EQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKaLETWYKRDLASlgvdpdVIAKLKREIRTLERKIER 786
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941652 1479 MKAqedfDKIELEKYKQLYQEEFRARK-SLSSKLNKTSEKLEEASSKLLLEEQQNRSLLSTLST 1541
Cdd:pfam12128 787 IAV----RRQEVLRYFDWYQETWLQRRpRLATQLSNIERAISELQQQLARLIADTKLRRAKLEM 846
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
688-1214 |
1.81e-10 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 66.30 E-value: 1.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 688 LTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVE 767
Cdd:pfam15921 375 LDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 768 ARQQLEASLRTLEMELKTVKSHLNQVLEERneTQRQLSREQNARMLQDgILASHLCKQKEIEMTQKKMTSEVSVSHEKEK 847
Cdd:pfam15921 455 GKNESLEKVSSLTAQLESTKEMLRKVVEEL--TAKKMTLESSERTVSD-LTASLQEKERAIEATNAEITKLRSRVDLKLQ 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 848 DLLH-KNQrlQDEVAVLRLEMDTIKSHNQEKEKRyledIKIANEKNDNLQRMVKLNEETFTKTIF---QYTGQLNSLK-- 921
Cdd:pfam15921 532 ELQHlKNE--GDHLRNVQTECEALKLQMAEKDKV----IEILRQQIENMTQLVGQHGRTAGAMQVekaQLEKEINDRRle 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 922 -AENTMLSSKLDNEKQNKERLETDVESFRSRLASA----LHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRD 996
Cdd:pfam15921 606 lQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAgserLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRN 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 997 NNEVLSQQLSKTERKLNSLEIEFHHTKDELR----------------EKTLALKHAQRDLSQTQCQMKEV--------EH 1052
Cdd:pfam15921 686 KSEEMETTTNKLKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEamtnankeKH 765
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1053 MFQDEQGKVSKFMGKQESIEERLA-QLQSENTLLRQQLDDAANKAESKDKTIVNIQdQFQDVLTRFQAESQR----HSLR 1127
Cdd:pfam15921 766 FLKEEKNKLSQELSTVATEKNKMAgELEVLRSQERRLKEKVANMEVALDKASLQFA-ECQDIIQRQEQESVRlklqHTLD 844
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1128 LEDRNQELVSECSHLRERLCQYENEKAEREVVVRQlqQELADTLKKQSMSEASLEvssryrsnlEEEARDLKKKLGQLRS 1207
Cdd:pfam15921 845 VKELQGPGYTSNSSMKPRLLQPASFTRTHSNVPSS--QSTASFLSHHSRKTNALK---------EDPTRDLKQLLQELRS 913
|
....*..
gi 568941652 1208 QLQEARD 1214
Cdd:pfam15921 914 VINEEPT 920
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
692-1354 |
2.43e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.43 E-value: 2.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 692 LKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQcqseveaRQQ 771
Cdd:TIGR04523 49 LKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ-------KNK 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 772 LEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNArmlqdgilASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLh 851
Cdd:TIGR04523 122 LEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNK--------YNDLKKQKEELENELNLLEKEKLNIQKNIDKI- 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 852 KNQRLQDEVAVLRLEmdTIKSHNQEKEKRYLEDIKIANEKNDNLQRmvKLNEETFTKTIFQYT-GQLNSLKAENTMLSSK 930
Cdd:TIGR04523 193 KNKLLKLELLLSNLK--KKIQKNKSLESQISELKKQNNQLKDNIEK--KQQEINEKTTEISNTqTQLNQLKDEQNKIKKQ 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 931 LDNEKQNKERLETDVESFRsrlasalhdhAEIQTAKRDLEIAFQRARDEWFRvkdKMNFDMSNLRDNNEVLSQQLSKTER 1010
Cdd:TIGR04523 269 LSEKQKELEQNNKKIKELE----------KQLNQLKSEISDLNNQKEQDWNK---ELKSELKNQEKKLEEIQNQISQNNK 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1011 KLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHmfqdeqgkvskfmgKQESIEERLAQLQSENTLLRQQLD 1090
Cdd:TIGR04523 336 IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK--------------ENQSYKQEIKNLESQINDLESKIQ 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1091 DAANKAESKDKTIVNIQDQFQdvltrfqaesqrhslRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQeLADT 1170
Cdd:TIGR04523 402 NQEKLNQQKDEQIKKLQQEKE---------------LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDN-TRES 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1171 LKKQsMSEASLEVSSrYRSNLEEEARDLKKK---LGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQ 1247
Cdd:TIGR04523 466 LETQ-LKVLSRSINK-IKQNLEQKQKELKSKekeLKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDL 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1248 SEEIDQLQENLSRVNLSEEDKEKLQKLTELKEslecTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDI 1327
Cdd:TIGR04523 544 EDELNKDDFELKKENLEKEIDEKNKEIEELKQ----TQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
|
650 660
....*....|....*....|....*..
gi 568941652 1328 KNNHLEMDiPVSTLIKKIDDLTAKLET 1354
Cdd:TIGR04523 620 EKAKKENE-KLSSIIKNIKSKKNKLKQ 645
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
698-1533 |
1.19e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 63.45 E-value: 1.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 698 KYKGLQKEMSETEEVKSRLehekvGWEQELCRLRFALKQEEEKRRSADQLSEKtsEQLRRKGEQCQSEVEARQQLEASLR 777
Cdd:pfam02463 171 KKEALKKLIEETENLAELI-----IDLEELKLQELKLKEQAKKALEYYQLKEK--LELEEEYLLYLDYLKLNEERIDLLQ 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 778 TLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLC-KQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRL 856
Cdd:pfam02463 244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKlLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 857 QDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKL--NEETFTKTIFQYTGQLNSLKAENTMLSSKLDNE 934
Cdd:pfam02463 324 KKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 935 KQNKERLetdvesfrSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEV-LSQQLSKTERKLN 1013
Cdd:pfam02463 404 EKEAQLL--------LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLkDELELKKSEDLLK 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1014 SLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQD-EQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDA 1092
Cdd:pfam02463 476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1093 ANKAESKDKTIVNIQDQFQDVLTRFQAESqRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLK 1172
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLI-PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1173 KQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARdqhreavhHAEKMEDHLQKLELEKSKFEITIKKQSEEID 1252
Cdd:pfam02463 635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEL--------LEIQELQEKAESELAKEEILRRQLEIKKKEQ 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1253 QLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEF--KEVLKMTKKELNEYENRELNLRQDIKNN 1330
Cdd:pfam02463 707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRlkKEEKEEEKSELSLKEKELAEEREKTEKL 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1331 HLEMDIpVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVE 1410
Cdd:pfam02463 787 KVEEEK-EEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITK 865
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1411 HSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQL------RENSNASVRSQMELRIKDLESQLYRMKAQED 1484
Cdd:pfam02463 866 EELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlnlleeKENEIEERIKEEAEILLKYEEEPEELLLEEA 945
|
810 820 830 840
....*....|....*....|....*....|....*....|....*....
gi 568941652 1485 FDKIELEKYKQlyQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNR 1533
Cdd:pfam02463 946 DEKEKEENNKE--EEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNK 992
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
43-190 |
1.59e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 62.20 E-value: 1.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 43 IHDKDMGK--IHKAASVGDvAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIK 120
Cdd:PHA02878 162 MKDRHKGNtaLHYATENKD-QRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHI 240
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941652 121 AV-QCQEEECAAILLDHGADPNVMDS-SGNTALHYAVYSENTSMAakLLAHNANIEAKNKDDLTPMLLAVKE 190
Cdd:PHA02878 241 SVgYCKDYDILKLLLEHGVDVNAKSYiLGLTALHSSIKSERKLKL--LLEYGADINSLNSYKLTPLSSAVKQ 310
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
25-212 |
2.68e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 62.00 E-value: 2.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 25 CVGFGRESASGSHVPRYHIHDK-DMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVER 103
Cdd:PHA02876 121 CIHILKEAISGNDIHYDKINESiEYMKLIKERIQQDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSY 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 104 ---------------KCEIDARDSESSTALI--------------KAVQCQEEECAAILLDHGADPNVMDSSGNTALHYA 154
Cdd:PHA02876 201 gadvniialddlsvlECAVDSKNIDTIKAIIdnrsninkndlsllKAIRNEDLETSLLLYDAGFSVNSIDDCKNTPLHHA 280
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 155 VYSENTS-MAAKLLAHNANIEAKNKDDLTPMLLAVKEN-KQHIVEFLVKKKASIHAVDQL 212
Cdd:PHA02876 281 SQAPSLSrLVPKLLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRL 340
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
41-210 |
2.89e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 61.43 E-value: 2.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 41 YHIHDKDMGKIHKAASVGdvAKVQHILILGKSGVNDRDK-KDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALI 119
Cdd:PHA02878 129 QTIDLVYIDKKSKDDIIE--AEITKLLLSYGADINMKDRhKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLH 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 120 KAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAV-YSENTSMAAKLLAHNANIEAKNK-DDLTPMLLAVKEnkQHIVE 197
Cdd:PHA02878 207 HAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVgYCKDYDILKLLLEHGVDVNAKSYiLGLTALHSSIKS--ERKLK 284
|
170
....*....|...
gi 568941652 198 FLVKKKASIHAVD 210
Cdd:PHA02878 285 LLLEYGADINSLN 297
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1129-1540 |
3.03e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.00 E-value: 3.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1129 EDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKklgqLRSQ 1208
Cdd:PRK03918 164 YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE----LKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1209 LQEARDQhreavhhAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQE 1288
Cdd:PRK03918 240 IEELEKE-------LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREI 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1289 QKRSSALEKELAEFKEVLK---MTKKELNEYENRELNLRQD---IKNNHLEMDiPVSTLIKKIDDLTAKLetassKCLHL 1362
Cdd:PRK03918 313 EKRLSRLEEEINGIEERIKeleEKEERLEELKKKLKELEKRleeLEERHELYE-EAKAKKEELERLKKRL-----TGLTP 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1363 GKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEK-LKQVNLFLQ 1441
Cdd:PRK03918 387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEyTAELKRIEK 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1442 AQAASQESLEQLREN-----------SNASVRSQMELRIKDLESQLyrmkaqEDFDKIELEKYKQLYQ---EEFRARKSL 1507
Cdd:PRK03918 467 ELKEIEEKERKLRKElrelekvlkkeSELIKLKELAEQLKELEEKL------KKYNLEELEKKAEEYEklkEKLIKLKGE 540
|
410 420 430
....*....|....*....|....*....|...
gi 568941652 1508 SSKLNKTSEKLEEASSKLLLEEQQNRSLLSTLS 1540
Cdd:PRK03918 541 IKSLKKELEKLEELKKKLAELEKKLDELEEELA 573
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
734-1520 |
3.79e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 61.99 E-value: 3.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 734 LKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRtlemelKTVKSHLNQvLEERNETQRQLSREQNARML 813
Cdd:TIGR00606 194 VRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR------EIVKSYENE-LDPLKNRLKEIEHNLSKIMK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 814 QDGILASHLCKQKEIEMTQK----KMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMD-TIKSHNQEKEKRYLEDIKIA 888
Cdd:TIGR00606 267 LDNEIKALKSRKKQMEKDNSelelKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQrELEKLNKERRLLNQEKTELL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 889 NEkndnlQRMVKLNEETFTKTIFQYTG--QLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAK 966
Cdd:TIGR00606 347 VE-----QGRLQLQADRHQEHIRARDSliQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKE 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 967 RdleiAFQRARDEwfrVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEiEFHHTKDELREKTLALKHAQRDLSQ---- 1042
Cdd:TIGR00606 422 R----LKQEQADE---IRDEKKGLGRTIELKKEILEKKQEELKFVIKELQ-QLEGSSDRILELDQELRKAERELSKaekn 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1043 --TQCQMKEVEHMfQDEQGKVSKfmgKQESIEERLAQLQSENTLLRQQLDDAANKAEsKDKTIVNIQDQFQDVLTRF--- 1117
Cdd:TIGR00606 494 slTETLKKEVKSL-QNEKADLDR---KLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD-KDEQIRKIKSRHSDELTSLlgy 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1118 -----QAESQRHSLR-----LEDRNQELVSECSHLRERLCQYENEKAER--------------------EVVVRQLQQEL 1167
Cdd:TIGR00606 569 fpnkkQLEDWLHSKSkeinqTRDRLAKLNKELASLEQNKNHINNELESKeeqlssyedklfdvcgsqdeESDLERLKEEI 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1168 ADTLKKQSMSEASLEVSSRYRSNLEEEA--------RDLKKKlGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSK 1239
Cdd:TIGR00606 649 EKSSKQRAMLAGATAVYSQFITQLTDENqsccpvcqRVFQTE-AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDE 727
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1240 FEITIKKQSEEIDQLQENLSRVnlseedKEKLQKLTELKESLECTVDQEQKRSSAL--EKELAE--FKEVLKMTKKELNE 1315
Cdd:TIGR00606 728 MLGLAPGRQSIIDLKEKEIPEL------RNKLQKVNRDIQRLKNDIEEQETLLGTImpEEESAKvcLTDVTIMERFQMEL 801
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1316 YENRELNLRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGKknqLLQQELLLMRTIQKKCGKLEKNKKQLEQ 1395
Cdd:TIGR00606 802 KDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRK---LIQDQQEQIQHLKSKTNELKSEKLQIGT 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1396 EVVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEKLkqvnlFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQ 1475
Cdd:TIGR00606 879 NLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLET-----FLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNI 953
|
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 568941652 1476 LYRMKAQEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEE 1520
Cdd:TIGR00606 954 HGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINE 998
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
677-1503 |
5.20e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.53 E-value: 5.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 677 LIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLR 756
Cdd:pfam02463 192 LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVL 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 757 RKGEQCQSEVEARQQLEASLRTLEMELKTVKSHL-NQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKKM 835
Cdd:pfam02463 272 KENKEEEKEKKLQEEELKLLAKEEEELKSELLKLeRRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 836 TSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKS----HNQEKEKRYlEDIKIANEKNDNLQRMVKLNEETFTKtif 911
Cdd:pfam02463 352 EAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSaaklKEEELELKS-EEEKEAQLLLELARQLEDLLKEEKKE--- 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 912 qytgqlnSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMnFDM 991
Cdd:pfam02463 428 -------ELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLE-ERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 992 SNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHA-----QRDLSQTQCQMKEVEHMFQ------DEQGK 1060
Cdd:pfam02463 500 QKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAistavIVEVSATADEVEERQKLVRaltelpLGARK 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1061 VSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLtrfQAESQRHSLRLEDRNQELVSecs 1140
Cdd:pfam02463 580 LRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTE---LTKLKESAKAKESGLRKGVS--- 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1141 hlrerLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAV 1220
Cdd:pfam02463 654 -----LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQ 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1221 HHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVnLSEEDKEKLQKLTELKESLEctvDQEQKRSSALEKELA 1300
Cdd:pfam02463 729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL-SLKEKELAEEREKTEKLKVE---EEKEEKLKAQEEELR 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1301 EFKEVLKMTKKELNEYENRELNL--RQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRT 1378
Cdd:pfam02463 805 ALEEELKEEAELLEEEQLLIEQEekIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1379 IQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERaRQDLVEKLKQVNLFLQAQAASQESLEQLRENSN 1458
Cdd:pfam02463 885 KDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL-LKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 568941652 1459 ASVRSQMELRIKDLES--QLYRMKAQEDFDKIELEKYKQLYQEEFRA 1503
Cdd:pfam02463 964 RLLLAKEELGKVNLMAieEFEEKEERYNKDELEKERLEEEKKKLIRA 1010
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
51-214 |
7.87e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 59.89 E-value: 7.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAY----GHPEVVTLLVERKCE-------------------- 106
Cdd:PHA02878 41 LHQAVEARNLDVVKSLLTRGHN-VNQPDHRDLTPLHIICKEpnklGMKEMIRSINKCSVFytlvaikdafnnrnveifki 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 107 --IDARDSESSTALIKAVQCQ-----EEECAAILLDHGADPNVMD-SSGNTALHYAVYSENTSMAAKLLAHNANIEAKNK 178
Cdd:PHA02878 120 ilTNRYKNIQTIDLVYIDKKSkddiiEAEITKLLLSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDK 199
|
170 180 190
....*....|....*....|....*....|....*.
gi 568941652 179 DDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLGS 214
Cdd:PHA02878 200 TNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGN 235
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
870-1520 |
1.19e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 60.03 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 870 IKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTK---TIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVe 946
Cdd:TIGR04523 27 IANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKdeeKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDL- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 947 sfrSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDEL 1026
Cdd:TIGR04523 106 ---SKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1027 REKtlalkhaQRDLSQTQCQMKEVEHMFQDEQGKVSKfmgkQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNI 1106
Cdd:TIGR04523 183 LNI-------QKNIDKIKNKLLKLELLLSNLKKKIQK----NKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNT 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1107 QDQFQDVLTrfqaESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKkqsmseaslevssr 1186
Cdd:TIGR04523 252 QTQLNQLKD----EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELK-------------- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1187 yrsnleEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENlsrvnlSEE 1266
Cdd:TIGR04523 314 ------SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE------NQS 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1267 DKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNnhLEMDIPV-STLIKKI 1345
Cdd:TIGR04523 382 YKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKD--LTNQDSVkELIIKNL 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1346 DDLTAKLETASSKCLHLGKKNQLlqqelllmrtiqkkcgKLEKNKKQLEQEVVNLRSHMEKNmvehsqaqqyareveera 1425
Cdd:TIGR04523 460 DNTRESLETQLKVLSRSINKIKQ----------------NLEQKQKELKSKEKELKKLNEEK------------------ 505
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1426 rQDLVEKLKQVNlflQAQAASQESLEQLRensnaSVRSQMELRIKDLESQLYRMKaqEDFDKIELEKYKQLYQEEFRARK 1505
Cdd:TIGR04523 506 -KELEEKVKDLT---KKISSLKEKIEKLE-----SEKKEKESKISDLEDELNKDD--FELKKENLEKEIDEKNKEIEELK 574
|
650
....*....|....*
gi 568941652 1506 SLSSKLNKTSEKLEE 1520
Cdd:TIGR04523 575 QTQKSLKKKQEEKQE 589
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
707-1286 |
1.21e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 60.05 E-value: 1.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 707 SETEEVKSRLEHEKV-GWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLrrkgeqcqSEVEARQQleaslrtlemELKT 785
Cdd:PRK02224 194 AQIEEKEEKDLHERLnGLESELAELDEEIERYEEQREQARETRDEADEVL--------EEHEERRE----------ELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 786 VKSHLNQVLEERNETQRQlsREQNARmlqdgilashlckqkeiemtqkkmtsEVSVSHEKEKDLLHKNQRLQDEVAVLRL 865
Cdd:PRK02224 256 LEAEIEDLRETIAETERE--REELAE--------------------------EVRDLRERLEELEEERDDLLAEAGLDDA 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 866 EMDTIKSHNQEKEKRyledikiANEKNDNLQRmVKLNEETFTKTIFQYTGQLNSLKAENTmlsskldnEKQNK-ERLETD 944
Cdd:PRK02224 308 DAEAVEARREELEDR-------DEELRDRLEE-CRVAAQAHNEEAESLREDADDLEERAE--------ELREEaAELESE 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 945 VESFRSRLASALHDHAEIQTAKRDLEIAFQRARDewfrvkdkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKD 1024
Cdd:PRK02224 372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPV-----------DLGNAEDFLEELREERDELREREAELEATLRTARE 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1025 ELREktlalkhAQRDLSQTQC-----QMKEVEHMFQDEQGKVskfmgKQESIEERLAQLQSENTLLRQQLDDA--ANKAE 1097
Cdd:PRK02224 441 RVEE-------AEALLEAGKCpecgqPVEGSPHVETIEEDRE-----RVEELEAELEDLEEEVEEVEERLERAedLVEAE 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1098 SKDKTIVNIQDQFQDVLTRFQAESQRHSLRLE---DRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELAdTLKKQ 1174
Cdd:PRK02224 509 DRIERLEERREDLEELIAERRETIEEKRERAEelrERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA-ELKER 587
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1175 SMSEASLEVSSRYRSNLEEEARDLKKKLGQL-------RSQLQEARDQHREAvhHAEKMEDHLQKLELEKSKFEITIKKQ 1247
Cdd:PRK02224 588 IESLERIRTLLAAIADAEDEIERLREKREALaelnderRERLAEKRERKREL--EAEFDEARIEEAREDKERAEEYLEQV 665
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 568941652 1248 SEEIDQLQEN----LSRVNLSEEDKEKLQKLTELKESLECTVD 1286
Cdd:PRK02224 666 EEKLDELREErddlQAEIGAVENELEELEELRERREALENRVE 708
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
83-207 |
1.53e-08 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 59.26 E-value: 1.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 83 TALHLACAYGHPEVVTLLVERKCE-IDARD-----SESSTALIK--------AVQCQEEECAAILLDHGADPNVMDSSGN 148
Cdd:cd22192 91 TALHIAVVNQNLNLVRELIARGADvVSPRAtgtffRPGPKNLIYygehplsfAACVGNEEIVRLLIEHGADIRAQDSLGN 170
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941652 149 TALHYAVYSENTSMAAK----LLAHNANIEA------KNKDDLTPMLLAVKENKQHIVEFLVKKKASIH 207
Cdd:cd22192 171 TVLHILVLQPNKTFACQmydlILSYDKEDDLqpldlvPNNQGLTPFKLAAKEGNIVMFQHLVQKRRHIQ 239
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
876-1323 |
1.72e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 59.69 E-value: 1.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 876 EKEKRYLEDIKIANEkndNLQRMVKLNEETFTKTIfqytGQLNSLKAENTMLSSKLDNEKQNKERLEtdveSFRSRLASA 955
Cdd:PRK03918 175 KRRIERLEKFIKRTE---NIEELIKEKEKELEEVL----REINEISSELPELREELEKLEKEVKELE----ELKEEIEEL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 956 LHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVlsQQLSKTERKLNSLEIEFhhtKDELREKTLALKH 1035
Cdd:PRK03918 244 EKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL--KEKAEEYIKLSEFYEEY---LDELREIEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1036 AQRDLSQTQCQMKEVEhmfqDEQGKVSKFMGKQESIEERLAQLQSENTLL---RQQLDDAAN-KAESKDKTIVNIQDQFQ 1111
Cdd:PRK03918 319 LEEEINGIEERIKELE----EKEERLEELKKKLKELEKRLEELEERHELYeeaKAKKEELERlKKRLTGLTPEKLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1112 DvltrfqaesqrhslrLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQ----------QELADTLKKQSMSEASL 1181
Cdd:PRK03918 395 E---------------LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTA 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1182 EVSsryrsNLEEEARDLKKKLGQLRSQLQEardqhreavhhaekmedhLQKLELEKSKFeITIKKQSEEIDQLQENLSRV 1261
Cdd:PRK03918 460 ELK-----RIEKELKEIEEKERKLRKELRE------------------LEKVLKKESEL-IKLKELAEQLKELEEKLKKY 515
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941652 1262 NLS--EEDKEKLQKLTELKESLEC---TVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNL 1323
Cdd:PRK03918 516 NLEelEKKAEEYEKLKEKLIKLKGeikSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
723-1531 |
1.92e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 59.68 E-value: 1.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 723 WEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQR 802
Cdd:TIGR00606 243 YENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELV 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 803 QLSREQNaRMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDT---IKSHNQEKEK 879
Cdd:TIGR00606 323 DCQRELE-KLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSerqIKNFHTLVIE 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 880 RYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDN-----------EKQNKERLETDVESF 948
Cdd:TIGR00606 402 RQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEElkfvikelqqlEGSSDRILELDQELR 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 949 RSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERK----------------- 1011
Cdd:TIGR00606 482 KAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKmdkdeqirkiksrhsde 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1012 LNSLEIEFHHTK---DELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERL------AQLQSEN 1082
Cdd:TIGR00606 562 LTSLLGYFPNKKqleDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDL 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1083 TLLRQQLDDAAnKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQ 1162
Cdd:TIGR00606 642 ERLKEEIEKSS-KQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKK 720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1163 LQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHL------QKLELE 1236
Cdd:TIGR00606 721 KEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLtdvtimERFQME 800
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1237 KSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLEctvdqeqkrssALEKELAEFKEVLKMTKKELNEY 1316
Cdd:TIGR00606 801 LKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIE-----------LNRKLIQDQQEQIQHLKSKTNEL 869
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1317 ENRELNLRQDIKNNHlEMDIPVSTLIKKIDDLTAKLETASSKCLHLgkKNQLLQQELLLMRTIQKKcgklEKNKKQLEQE 1396
Cdd:TIGR00606 870 KSEKLQIGTNLQRRQ-QFEEQLVELSTEVQSLIREIKDAKEQDSPL--ETFLEKDQQEKEELISSK----ETSNKKAQDK 942
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1397 VVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQmELRIKDLESQL 1476
Cdd:TIGR00606 943 VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ-KIQERWLQDNL 1021
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 1477 YRMKAQEDFDKIELEK---YKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQ 1531
Cdd:TIGR00606 1022 TLRKRENELKEVEEELkqhLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
115-167 |
1.97e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.89 E-value: 1.97e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 568941652 115 STALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLL 167
Cdd:pfam13637 2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
675-1279 |
2.06e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 59.31 E-value: 2.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 675 KRLIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQ 754
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 755 LRRKGEqcqsevearqqLEASLRTLEMELKTVKSHLnQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKK 834
Cdd:PRK03918 251 EGSKRK-----------LEEKIRELEERIEELKKEI-EELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 835 MTSEVSVSHEKEKDLLHKNQRLQDevavlrlemdtIKSHNQEKEKRYLEdikianekndnLQRMVKLNEEtftktIFQYT 914
Cdd:PRK03918 319 LEEEINGIEERIKELEEKEERLEE-----------LKKKLKELEKRLEE-----------LEERHELYEE-----AKAKK 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 915 GQLNSLKAENTMLS-----SKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQR--------ARDEWF 981
Cdd:PRK03918 372 EELERLKKRLTGLTpekleKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 982 RVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLA--LKHAQRDLSQTQCQ-MKEVEHMFQDEQ 1058
Cdd:PRK03918 452 ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqLKELEEKLKKYNLEeLEKKAEEYEKLK 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1059 GKVSKFMGKQESIE---ERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQ-DQFQDVLTRFQAESQRHSLRLEDRNQE 1134
Cdd:PRK03918 532 EKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEYLELKDAE 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1135 lvSECSHLRERLcqyenEKAEREVVvrQLQQELADTLKKQSMSEASLEVSSRYRSnlEEEARDLKKKLGQLRSQLQEARD 1214
Cdd:PRK03918 612 --KELEREEKEL-----KKLEEELD--KAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRA 680
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568941652 1215 QHREAVHHAEKMEDHLQKLELEKSKfeitIKKQSEEIDQLQENLSRVnlsEEDKEKLQKL-TELKE 1279
Cdd:PRK03918 681 ELEELEKRREEIKKTLEKLKEELEE----REKAKKELEKLEKALERV---EELREKVKKYkALLKE 739
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
703-1330 |
4.79e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.19 E-value: 4.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 703 QKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEK--TSEQLRRKGEQCQSEVEARQQLE---ASLR 777
Cdd:pfam05483 103 QKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENnaTRHLCNLLKETCARSAEKTKKYEyerEETR 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 778 TLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCK--QKEIEMTQKKMTSEVSVSHEKE---KDLLHK 852
Cdd:pfam05483 183 QVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeyKKEINDKEKQVSLLLIQITEKEnkmKDLTFL 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 853 NQRLQDEVAVL----RLEMDTIKSHNQEKE--KRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQ---------- 916
Cdd:pfam05483 263 LEESRDKANQLeektKLQDENLKELIEKKDhlTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEkeaqmeelnk 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 917 --------LNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQrardewfRVKDKMN 988
Cdd:pfam05483 343 akaahsfvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE-------ELKKILA 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 989 FDMSNLRDNNEV--LSQQLSKTERKLNSL----EIEFHHTKDELREKTLALKHAQRdlsqtqcQMKEVEHMFQDEQGKVS 1062
Cdd:pfam05483 416 EDEKLLDEKKQFekIAEELKGKEQELIFLlqarEKEIHDLEIQLTAIKTSEEHYLK-------EVEDLKTELEKEKLKNI 488
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1063 KFMGKQEsieerlaQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQA-ESQRHSLR--LEDRNQELVSEC 1139
Cdd:pfam05483 489 ELTAHCD-------KLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENlEEKEMNLRdeLESVREEFIQKG 561
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1140 SHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKK--------------KLGQL 1205
Cdd:pfam05483 562 DEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKkgsaenkqlnayeiKVNKL 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1206 RSQLQEARDQHREAVHHAEK--------MEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSR-VNLSEEDKEKLQKLTE 1276
Cdd:pfam05483 642 ELELASAKQKFEEIIDNYQKeiedkkisEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEmVALMEKHKHQYDKIIE 721
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 1277 LKES-LECTVDQEQKRSS---ALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNN 1330
Cdd:pfam05483 722 ERDSeLGLYKNKEQEQSSakaALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKEN 779
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
74-121 |
1.47e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 49.65 E-value: 1.47e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 568941652 74 VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKA 121
Cdd:pfam13857 9 LNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
869-1535 |
1.68e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 56.27 E-value: 1.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 869 TIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENT------MLSSKLDNEKQNKERLE 942
Cdd:pfam05483 96 SIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNAtrhlcnLLKETCARSAEKTKKYE 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 943 TDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEwfrVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHT 1022
Cdd:pfam05483 176 YEREETRQVYMDLNNNIEKMILAFEELRVQAENARLE---MHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEK 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1023 KDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAAnkaeskdKT 1102
Cdd:pfam05483 253 ENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIAT-------KT 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1103 IVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQEladtlkkqsmsEASLE 1182
Cdd:pfam05483 326 ICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKK-----------SSELE 394
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1183 VSSRYRSNLEEEARDLKKKLGQLRSQL----------QEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEID 1252
Cdd:pfam05483 395 EMTKFKNNKEVELEELKKILAEDEKLLdekkqfekiaEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVE 474
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1253 QLQENLsrvnlsEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHL 1332
Cdd:pfam05483 475 DLKTEL------EKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRD 548
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1333 EMDIPVSTLIKKIDDLTAKL----ETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRshmEKNM 1408
Cdd:pfam05483 549 ELESVREEFIQKGDEVKCKLdkseENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK---KKGS 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1409 VEHSQAQQYAREVE------ERARQDLVEKLKQVNLFLQAQAASQESL----EQLRENSNASVRSQMEL------RIKDL 1472
Cdd:pfam05483 626 AENKQLNAYEIKVNklelelASAKQKFEEIIDNYQKEIEDKKISEEKLleevEKAKAIADEAVKLQKEIdkrcqhKIAEM 705
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941652 1473 ESQLYRMKAQedFDKI------ELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNRSL 1535
Cdd:pfam05483 706 VALMEKHKHQ--YDKIieerdsELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKL 772
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
969-1355 |
1.69e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.93 E-value: 1.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 969 LEIAFQRARDEWFRVKDKmnfdmsnlrdNNEVLSQQLSKTERKLNSLEIEfhhtKDELREKTLALKHAQRDLSQTQCQMK 1048
Cdd:COG4717 47 LLERLEKEADELFKPQGR----------KPELNLKELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1049 EVEHMFQ--DEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLD---DAANKAESKDKTIVNIQDQFQDVLTRFQAESQR 1123
Cdd:COG4717 113 ELREELEklEKLLQLLPLYQELEALEAELAELPERLEELEERLEelrELEEELEELEAELAELQEELEELLEQLSLATEE 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1124 HSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEA------------------------ 1179
Cdd:COG4717 193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallallglggsllsli 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1180 --------------SLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEAR--------------------------DQHREA 1219
Cdd:COG4717 273 ltiagvlflvlgllALLFLLLAREKASLGKEAEELQALPALEELEEEEleellaalglppdlspeellelldriEELQEL 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1220 VHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSS--ALEK 1297
Cdd:COG4717 353 LREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeELEE 432
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 1298 ELAEFKEVLKMTKKELNEYENRELNLRQDIKnnHLEMDIPVSTLIKKIDDLTAKLETA 1355
Cdd:COG4717 433 ELEELEEELEELEEELEELREELAELEAELE--QLEEDGELAELLQELEELKAELREL 488
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1130-1329 |
2.09e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.16 E-value: 2.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1130 DRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQL 1209
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1210 QEARDQHREAVHHAEKMEDHLQKLELEKSK-----------FEITIKKQSEEIDQLQENLsrvnlsEEDKEKLQKLTELK 1278
Cdd:COG4942 100 EAQKEELAELLRALYRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELRADL------AELAALRAELEAER 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568941652 1279 ESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKN 1329
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
618-1211 |
2.72e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.71 E-value: 2.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 618 AAVDNLDDFTESSETASEDHELQGPDSESILCAIEHLRleckdtASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMEN 697
Cdd:COG1196 229 LLLLKLRELEAELEELEAELEELEAELEELEAELAELE------AELEELRLELEELELELEEAQAEEYELLAELARLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 698 KYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLR 777
Cdd:COG1196 303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 778 TLEMELKTVKSHLNQVLEERNETQRQLSREQNARmlqdgilASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQ 857
Cdd:COG1196 383 ELAEELLEALRAAAELAAQLEELEEAEEALLERL-------ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 858 DEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKN---DNLQRMVKLNEEtftktiFQYTGQLNSLKAENTMLSSKLDNE 934
Cdd:COG1196 456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAarlLLLLEAEADYEG------FLEGVKAALLLAGLRGLAGAVAVL 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 935 KQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNfdmsNLRDNNEVLSQQLSKTERKLNS 1014
Cdd:COG1196 530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR----ARAALAAALARGAIGAAVDLVA 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1015 LEIEFHHTKDELREKTLALK-HAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAA 1093
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1094 NKAEskdktivniqdqfqdvltrfQAESQRHSLRLEDRNQELvsecsHLRERLCQYENEKAEREVVVRQLQQELADTLKK 1173
Cdd:COG1196 686 ERLA--------------------EEELELEEALLAEEEEER-----ELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
|
570 580 590
....*....|....*....|....*....|....*...
gi 568941652 1174 QSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQE 1211
Cdd:COG1196 741 LLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
696-1335 |
3.71e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 55.44 E-value: 3.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 696 ENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKG--EQCQSEVEARQQLE 773
Cdd:TIGR00606 318 ERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGfeRGPFSERQIKNFHT 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 774 ASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKN 853
Cdd:TIGR00606 398 LVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELD 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 854 QRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIK--IANEKNDNLQRMVKLNEETFTKTI-------------------FQ 912
Cdd:TIGR00606 478 QELRKAERELSKAEKNSLTETLKKEVKSLQNEKadLDRKLRKLDQEMEQLNHHTTTRTQmemltkdkmdkdeqirkikSR 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 913 YTGQLNSLKAE---NTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNF 989
Cdd:TIGR00606 558 HSDELTSLLGYfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 990 --DMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDelrEKTLALKHAQRDLsQTQcqmKEVEHMFQDEQGKVSKFMGK 1067
Cdd:TIGR00606 638 esDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTD---ENQSCCPVCQRVF-QTE---AELQEFISDLQSKLRLAPDK 710
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1068 QESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQ--------AESQRHSLRLEDRNQELVSEC 1139
Cdd:TIGR00606 711 LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQrlkndieeQETLLGTIMPEEESAKVCLTD 790
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1140 SHLRERLcQYENEKAEREV--------------VVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQL 1205
Cdd:TIGR00606 791 VTIMERF-QMELKDVERKIaqqaaklqgsdldrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNEL 869
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1206 RSQlqeaRDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEI--------DQLQENLSRVNLSEEDKEKLQ-KLTE 1276
Cdd:TIGR00606 870 KSE----KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDspletfleKDQQEKEELISSKETSNKKAQdKVND 945
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941652 1277 LKESlectVDQEQKRSSALEKELAEFKEVLKMTKK--------ELNEYENRELNLRQDIKNNHLEMD 1335
Cdd:TIGR00606 946 IKEK----VKNIHGYMKDIENKIQDGKDDYLKQKEtelntvnaQLEECEKHQEKINEDMRLMRQDID 1008
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
787-1433 |
4.53e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 55.12 E-value: 4.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 787 KSHLNQVLEERN----ETQRQLSREQNARMLQDGILASHL----CKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQD 858
Cdd:pfam15921 73 KEHIERVLEEYShqvkDLQRRLNESNELHEKQKFYLRQSVidlqTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 859 EVAVLR-LEMDTIKSHNQEKEK----------------RYLEDIKIANEK----NDNLQRM---------VKLNEETFTK 908
Cdd:pfam15921 153 ELEAAKcLKEDMLEDSNTQIEQlrkmmlshegvlqeirSILVDFEEASGKkiyeHDSMSTMhfrslgsaiSKILRELDTE 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 909 T------IFQYTGQLNSLKAENT-----MLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTakrDLEIAFQRAR 977
Cdd:pfam15921 233 IsylkgrIFPVEDQLEALKSESQnkielLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQS---QLEIIQEQAR 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 978 DE---WFRVKDKMNFDMSNLR-----------DNNEVLSQQL---------SKTER------------KLNSLEIEFHHT 1022
Cdd:pfam15921 310 NQnsmYMRQLSDLESTVSQLRselreakrmyeDKIEELEKQLvlanselteARTERdqfsqesgnlddQLQKLLADLHKR 389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1023 KDELR-EK-------------TLALKHAQRDLSQTQCQMKEVEHMFQ----DEQGKVSKFM----GKQESIEE---RLAQ 1077
Cdd:pfam15921 390 EKELSlEKeqnkrlwdrdtgnSITIDHLRRELDDRNMEVQRLEALLKamksECQGQMERQMaaiqGKNESLEKvssLTAQ 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1078 LQSENTLLRQQLDDAANKA---ESKDKTIVNIQDQFQDVLTRFQAES-------QRHSLRLEDRnQELVSECSHLRERLC 1147
Cdd:pfam15921 470 LESTKEMLRKVVEELTAKKmtlESSERTVSDLTASLQEKERAIEATNaeitklrSRVDLKLQEL-QHLKNEGDHLRNVQT 548
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1148 QYENEK---AEREVVVRQLQQELADTLKKQSMseaslevSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAE 1224
Cdd:pfam15921 549 ECEALKlqmAEKDKVIEILRQQIENMTQLVGQ-------HGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR 621
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1225 KMEDHLQKLELEKSKFeitIKKQSEEIDQLQE-NLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFK 1303
Cdd:pfam15921 622 ELEARVSDLELEKVKL---VNAGSERLRAVKDiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK 698
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1304 EVLKMTKKELNEYENRELNLRQdiKNNH-----LEMDIPVSTLIKKIDDLTAKLE------TASSKCLHLGK--KNQLLQ 1370
Cdd:pfam15921 699 MQLKSAQSELEQTRNTLKSMEG--SDGHamkvaMGMQKQITAKRGQIDALQSKIQfleeamTNANKEKHFLKeeKNKLSQ 776
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941652 1371 QELLLMRTIQKKCGKLE---KNKKQLEQEVVNLRSHMEKNMVEHSQAQQ-YAREVEERARQDLVEKL 1433
Cdd:pfam15921 777 ELSTVATEKNKMAGELEvlrSQERRLKEKVANMEVALDKASLQFAECQDiIQRQEQESVRLKLQHTL 843
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1069-1541 |
7.35e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 54.41 E-value: 7.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1069 ESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQdqfqdvLTRFQAESQRHSLR-----LEDRNQELVSECSHLR 1143
Cdd:pfam01576 85 EEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQ------LEKVTTEAKIKKLEedillLEDQNSKLSKERKLLE 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1144 ERLCQYENEKAEREVVVRQLQQ----------ELADTLKKQSMSEASLEVSSRyrsNLEEEARDLKKKLGQLRSQLQEAR 1213
Cdd:pfam01576 159 ERISEFTSNLAEEEEKAKSLSKlknkheamisDLEERLKKEEKGRQELEKAKR---KLEGESTDLQEQIAELQAQIAELR 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1214 DQHREavhHAEKMEDHLQKLELEKSKFEITIKKQSE---EIDQLQENLSRVNLSEEDKEKLQK---------LTELKESL 1281
Cdd:pfam01576 236 AQLAK---KEEELQAALARLEEETAQKNNALKKIREleaQISELQEDLESERAARNKAEKQRRdlgeelealKTELEDTL 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1282 ECTVDQEQKRSSAlEKELAEFKEVLKmtkKELNEYENRELNLRQdiKNNhlemdipvstliKKIDDLTAKLETASSKCLH 1361
Cdd:pfam01576 313 DTTAAQQELRSKR-EQEVTELKKALE---EETRSHEAQLQEMRQ--KHT------------QALEELTEQLEQAKRNKAN 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1362 LGKKN----QLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLrshmeknMVEHSQAqqyareveERARQDLVEKLKQVN 1437
Cdd:pfam01576 375 LEKAKqaleSENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-------QARLSES--------ERQRAELAEKLSKLQ 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1438 LFLQAQAASQESLEqlrensNASVRSQMELriKDLESQLYrmKAQEdfdkielekykqLYQEEFRARKSLSSKLNKTSEK 1517
Cdd:pfam01576 440 SELESVSSLLNEAE------GKNIKLSKDV--SSLESQLQ--DTQE------------LLQEETRQKLNLSTRLRQLEDE 497
|
490 500
....*....|....*....|....
gi 568941652 1518 LEEASSKLLLEEQQNRSLLSTLST 1541
Cdd:pfam01576 498 RNSLQEQLEEEEEAKRNVERQLST 521
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
151-202 |
7.87e-07 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 48.57 E-value: 7.87e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 568941652 151 LHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKK 202
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH 52
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
699-1332 |
8.17e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.15 E-value: 8.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 699 YKGLQKEMSETEEVKSRLEhekvgweqELCRLRFALKQEEEKRRSADQLSEK-TSEQLRRKGEQCQSEVEarqQLEASLR 777
Cdd:COG4913 237 LERAHEALEDAREQIELLE--------PIRELAERYAAARERLAELEYLRAAlRLWFAQRRLELLEAELE---ELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 778 TLEMELKTVKSHLNQVLEERNETQRQLSReqnarmlQDGILASHLckQKEIEMTQkkmtsevsvshEKEKDLLHKNQRLQ 857
Cdd:COG4913 306 RLEAELERLEARLDALREELDELEAQIRG-------NGGDRLEQL--EREIERLE-----------RELEERERRRARLE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 858 DEVAVLRLEMDTIkshnqekEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIfqytGQLNSLKAENTMLSSKLDNEKQN 937
Cdd:COG4913 366 ALLAALGLPLPAS-------AEEFAALRAEAAALLEALEEELEALEEALAEAE----AALRDLRRELRELEAEIASLERR 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 938 KERLETDVESFRSRLASAL-----------------HDHAEIQTA--------KRDL---EIAFQRARdEWF-RVKDKMN 988
Cdd:COG4913 435 KSNIPARLLALRDALAEALgldeaelpfvgelievrPEEERWRGAiervlggfALTLlvpPEHYAAAL-RWVnRLHLRGR 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 989 FDMSNLRDNNEvlSQQLSKTE-----RKLNSLEIEFHHT-KDELREKTL--------ALKHAQRDLSQTqCQMKEVEHMF 1054
Cdd:COG4913 514 LVYERVRTGLP--DPERPRLDpdslaGKLDFKPHPFRAWlEAELGRRFDyvcvdspeELRRHPRAITRA-GQVKGNGTRH 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1055 Q-DEQGKVSK--FMGkqESIEERLAQLQSENTLLRQQLDDAANKAESkdktivnIQDQFQDVLTRFQAESQRHSLRLEDR 1131
Cdd:COG4913 591 EkDDRRRIRSryVLG--FDNRAKLAALEAELAELEEELAEAEERLEA-------LEAELDALQERREALQRLAEYSWDEI 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1132 N-QELVSECSHLRERLCQYENEKAErevvVRQLQQELaDTLKKQsmseaslevssryRSNLEEEARDLKKKLGQLRSQLQ 1210
Cdd:COG4913 662 DvASAEREIAELEAELERLDASSDD----LAALEEQL-EELEAE-------------LEELEEELDELKGEIGRLEKELE 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1211 EARDQHREA---VHHAEKMEDHLQKLELEKsKFEITIKKQSEeiDQLQENLSrvnlseedkEKLQKLTELKESLEctvdq 1287
Cdd:COG4913 724 QAEEELDELqdrLEAAEDLARLELRALLEE-RFAAALGDAVE--RELRENLE---------ERIDALRARLNRAE----- 786
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 568941652 1288 eqkrsSALEKELAEFKEVLKMTKKEL-------NEYenreLNLRQDIKNNHL 1332
Cdd:COG4913 787 -----EELERAMRAFNREWPAETADLdadleslPEY----LALLDRLEEDGL 829
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
130-224 |
9.31e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 53.75 E-value: 9.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 130 AAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHav 209
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHF-- 175
|
90
....*....|....*
gi 568941652 210 dQLGSNRQMFEYDGK 224
Cdd:PTZ00322 176 -ELGANAKPDSFTGK 189
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
133-187 |
2.06e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 46.19 E-value: 2.06e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 568941652 133 LLDHG-ADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLA 187
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
690-1429 |
2.13e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 2.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 690 GKLKRMENKYKGLQKEMSETEEVKSRLEH----EKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSE-QLRRKGEQCQS 764
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDarkaEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKaEEARKAEDAKK 1177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 765 EVEARQQLEasLRTLEmELKTVKSHLNQVLEERNETQRqlsREQNARMLQDGILASHLCKQKEIemtqkKMTSEVSVSHE 844
Cdd:PTZ00121 1178 AEAARKAEE--VRKAE-ELRKAEDARKAEAARKAEEER---KAEEARKAEDAKKAEAVKKAEEA-----KKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 845 KEKDLLHKNQRLQDEVAVLRLEMDTIKShnqeKEKRYLEDIKIANE--KNDNLQRMVKLNEETFTKTIFQYTGQLNSLKA 922
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADELKKAEEkkKADEAKKAEEKKKADEAKKKAEEAKKADEAKK 1322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 923 ENTMLSSKLDNEKQNKERLETDVESFRsrlasalhdhAEIQTAKRDLEIAFQRAR-DEWFRVKDKMNFDMSNLRDNNEVL 1001
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAK----------AEAEAAADEAEAAEEKAEaAEKKKEEAKKKADAAKKKAEEKKK 1392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1002 SQQLSKTERklnsleiEFHHTKDELREKTLALKHAQrDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSE 1081
Cdd:PTZ00121 1393 ADEAKKKAE-------EDKKKADELKKAAAAKKKAD-EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1082 NTLLRQQLDDAANKAESKDKTivniqdqfqDVLTRFQAESQRHS--LRLEDRNQELVSECSHLRERLCQYENEKAEREVV 1159
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKA---------DEAKKKAEEAKKKAdeAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK 1535
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1160 VRQLQQ----ELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLEL 1235
Cdd:PTZ00121 1536 ADEAKKaeekKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1236 EKSKFEITIKKQSEEIDQLQENLSRVnlSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFK--EVLKMTKKEL 1313
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKK--EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkaEEDEKKAAEA 1693
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1314 NEYENRELNLRQDIKNNHLEMdipvstlIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQL 1393
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEE-------KKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766
|
730 740 750
....*....|....*....|....*....|....*..
gi 568941652 1394 EQEVVNLRSHMEKNMVEHSQAQQYAREVE-ERARQDL 1429
Cdd:PTZ00121 1767 EKKAEEIRKEKEAVIEEELDEEDEKRRMEvDKKIKDI 1803
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1102-1323 |
2.33e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.61 E-value: 2.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1102 TIVNIQDQFQDvLTRFQ-----AESQRHSLR-LEDRNQELVsecsHLRERLCQYENEKAEREVVVRQLQQELADtlKKQS 1175
Cdd:COG4913 226 AADALVEHFDD-LERAHealedAREQIELLEpIRELAERYA----AARERLAELEYLRAALRLWFAQRRLELLE--AELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1176 MSEASLEvssryrsNLEEEARDLKKKLGQLRSQLQEARDQHREAVHhaekmeDHLQKLELEKSKFEITIKKQSEEIDQLQ 1255
Cdd:COG4913 299 ELRAELA-------RLEAELERLEARLDALREELDELEAQIRGNGG------DRLEQLEREIERLERELEERERRRARLE 365
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568941652 1256 ENLSRVNLSEED-----KEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNL 1323
Cdd:COG4913 366 ALLAALGLPLPAsaeefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI 438
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
74-203 |
2.40e-06 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 52.39 E-value: 2.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 74 VNDRDK----KDRTALHLACAYGHPEVVTLLVERKCEIDAR----------------DSESSTALIKAVQcqEEECAAIL 133
Cdd:TIGR00870 117 ANDQYTseftPGITALHLAAHRQNYEIVKLLLERGASVPARacgdffvksqgvdsfyHGESPLNAAACLG--SPSIVALL 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 134 LDHGADPNVMDSSGNTALHYAV-----YSENTSM-------AAKLLAHNANIEA----KNKDDLTPMLLAVKENK----Q 193
Cdd:TIGR00870 195 SEDPADILTADSLGNTLLHLLVmenefKAEYEELscqmynfALSLLDKLRDSKEleviLNHQGLTPLKLAAKEGRivlfR 274
|
170
....*....|
gi 568941652 194 HIVEFLVKKK 203
Cdd:TIGR00870 275 LKLAIKYKQK 284
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
56-251 |
2.41e-06 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 51.95 E-value: 2.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 56 SVGDVAKVqhILILGKSG--VNDRDKKDRTALHL-ACAYGHPEVVTLLVERKCEIDARDSESSTALIK--AVQCQEEECA 130
Cdd:PHA03095 58 SSEKVKDI--VRLLLEAGadVNAPERCGFTPLHLyLYNATTLDVIKLLIKAGADVNAKDKVGRTPLHVylSGFNINPKVI 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMA--AKLLAHNANIEAKNKDDLTP---MLLAVKENKQhIVEFLVKKKAS 205
Cdd:PHA03095 136 RLLLRKGADVNALDLYGMTPLAVLLKSRNANVEllRLLIDAGADVYAVDDRFRSLlhhHLQSFKPRAR-IVRELIRAGCD 214
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568941652 206 IHAVDQLGSNRQMFEYDGKRLQRSENSNPVDNGSEDGSLTRSYNTP 251
Cdd:PHA03095 215 PAATDMLGNTPLHSMATGSSCKRSLVLPLLIAGISINARNRYGQTP 260
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
936-1534 |
2.71e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.37 E-value: 2.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 936 QNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVkDKMNFDMSNLRDNNEVLSQQLSKTERKLNSL 1015
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLEEKIREL 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1016 EIEFHHTKDELREktlaLKHAQRDLSQtqcqMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAank 1095
Cdd:PRK03918 265 EERIEELKKEIEE----LEEKVKELKE----LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL--- 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1096 aESKDKTIVNIQDQFQDVLTRFQAESQRHslRLEDRNQELVSECSHLRERLCQYENEKAEREVvvrqlqqELADTLKKQS 1175
Cdd:PRK03918 334 -EEKEERLEELKKKLKELEKRLEELEERH--ELYEEAKAKKEELERLKKRLTGLTPEKLEKEL-------EELEKAKEEI 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1176 MSEASlEVSSRyRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKmeDHLQKLELEKSKFEITIKKQSEEIDQLQ 1255
Cdd:PRK03918 404 EEEIS-KITAR-IGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRK--ELLEEYTAELKRIEKELKEIEEKERKLR 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1256 ENLSRVNLSEEDKEKLQKLTELKESLEctvdqeqkrssALEKELAEF-KEVLKMTKKELNEYENRELNLRQDIKNnhlem 1334
Cdd:PRK03918 480 KELRELEKVLKKESELIKLKELAEQLK-----------ELEEKLKKYnLEELEKKAEEYEKLKEKLIKLKGEIKS----- 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1335 dipVSTLIKKIDDLTAKLetasskclhlgkknqllqqelllmRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHsqa 1414
Cdd:PRK03918 544 ---LKKELEKLEELKKKL------------------------AELEKKLDELEEELAELLKELEELGFESVEELEER--- 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1415 qqyAREVEERARQDLveKLKQVNLFLQAQAASQESLEQLRENSNASVrSQMELRIKDLESQLyrMKAQEDFDKIELEKYK 1494
Cdd:PRK03918 594 ---LKELEPFYNEYL--ELKDAEKELEREEKELKKLEEELDKAFEEL-AETEKRLEELRKEL--EELEKKYSEEEYEELR 665
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 568941652 1495 QLYQEEFRARKSLSSKLNKTSEKLEEASSKL--LLEEQQNRS 1534
Cdd:PRK03918 666 EEYLELSRELAGLRAELEELEKRREEIKKTLekLKEELEERE 707
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
147-200 |
3.71e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 45.73 E-value: 3.71e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 568941652 147 GNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLV 200
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
939-1519 |
3.98e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 52.04 E-value: 3.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 939 ERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTerkLNSLEIE 1018
Cdd:pfam15921 81 EEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNT---VHELEAA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1019 FHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEErlAQLQSENTLLRQQLDDAANKAES 1098
Cdd:pfam15921 158 KCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMST--MHFRSLGSAISKILRELDTEISY 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1099 KDKTIVNIQDQFQDVLTRFQAES----QRHSLRLEDRNQELVSECSHLRERLC----QYENEKAEREVVVRQLQQELADT 1170
Cdd:pfam15921 236 LKGRIFPVEDQLEALKSESQNKIelllQQHQDRIEQLISEHEVEITGLTEKASsarsQANSIQSQLEIIQEQARNQNSMY 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1171 LKKQSMSEASLevsSRYRSNLEEEAR-------DLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKL--ELEKSKFE 1241
Cdd:pfam15921 316 MRQLSDLESTV---SQLRSELREAKRmyedkieELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLlaDLHKREKE 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1242 ITIKKQSEE------------IDQLQENLSRVNLSEEDKEKLQKL--TELKESLECTVDQEQKRSSALEK------ELAE 1301
Cdd:pfam15921 393 LSLEKEQNKrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAmkSECQGQMERQMAAIQGKNESLEKvssltaQLES 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1302 FKEVLKMTKKELN----EYENRELNLrQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLgkknqllQQELLLMR 1377
Cdd:pfam15921 473 TKEMLRKVVEELTakkmTLESSERTV-SDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHL-------KNEGDHLR 544
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1378 TIQKKCGKLEKNKKQLEQEVVNLRSHMEkNMVEhsQAQQYAREveerARQDLVEKlKQVNLFLQAQAASQESLEQLRENS 1457
Cdd:pfam15921 545 NVQTECEALKLQMAEKDKVIEILRQQIE-NMTQ--LVGQHGRT----AGAMQVEK-AQLEKEINDRRLELQEFKILKDKK 616
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941652 1458 NASVRsQMELRIKDLESQLYRMKAQEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLE 1519
Cdd:pfam15921 617 DAKIR-ELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE 677
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
80-205 |
5.06e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 51.42 E-value: 5.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 80 KDRTALHLACAYGHPEVVTLLVERKCEIDARdseSSTALIKAVQC----------------QEEECAAILLDHGADP--- 140
Cdd:cd21882 72 QGQTALHIAIENRNLNLVRLLVENGADVSAR---ATGRFFRKSPGnlfyfgelplslaactNQEEIVRLLLENGAQPaal 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 141 NVMDSSGNTALHYAVYSEN---------TSMAAKLLAHNANI-------EAKNKDDLTPMLLAVKENKQHIVEFLVKKKA 204
Cdd:cd21882 149 EAQDSLGNTVLHALVLQADntpensafvCQMYNLLLSYGAHLdptqqleEIPNHQGLTPLKLAAVEGKIVMFQHILQREF 228
|
.
gi 568941652 205 S 205
Cdd:cd21882 229 S 229
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
99-154 |
6.01e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.03 E-value: 6.01e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 568941652 99 LLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYA 154
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
67-211 |
6.71e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 50.83 E-value: 6.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 67 LILGKSG--VNDRDKKDRTALHLAC-AYGHPEVVTLLVERKCEIDARDSESSTAL-IKAVQCQEEECAAILLDHGADPNV 142
Cdd:PHA02876 257 LLLYDAGfsVNSIDDCKNTPLHHASqAPSLSRLVPKLLERGADVNAKNIKGETPLyLMAKNGYDTENIRTLIMLGADVNA 336
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 143 MDSSGNTALHYA-VYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQ 211
Cdd:PHA02876 337 ADRLYITPLHQAsTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQ 406
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
888-1525 |
7.16e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.12 E-value: 7.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 888 ANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTmlsskldneKQNKERLE--TDVESFRSRLASALHDHAEIQTA 965
Cdd:TIGR00618 125 KSETEEVIHDLLKLDYKTFTRVVLLPQGEFAQFLKAKS---------KEKKELLMnlFPLDQYTQLALMEFAKKKSLHGK 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 966 KRDLEIAFQrardewfRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEI--EFHHTKDELREKTL----ALKHAQRD 1039
Cdd:TIGR00618 196 AELLTLRSQ-------LLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQshAYLTQKREAQEEQLkkqqLLKQLRAR 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1040 LSQTQCQMKEVEHMFQ--DEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLddaaNKAESKDKTIVNIQDQFQDVLTRF 1117
Cdd:TIGR00618 269 IEELRAQEAVLEETQEriNRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKM----RSRAKLLMKRAAHVKQQSSIEEQR 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1118 QAESQRHslRLEDRNQELVSECSHLRERLCQyenEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEA-- 1195
Cdd:TIGR00618 345 RLLQTLH--SQEIHIRDAHEVATSIREISCQ---QHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSaf 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1196 RDLKKKLGQLRSQLQEardQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQeNLSRVNLSEEDKEKL--QK 1273
Cdd:TIGR00618 420 RDLQGQLAHAKKQQEL---QQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQ-TKEQIHLQETRKKAVvlAR 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1274 LTELKEsLECTVDQE-----------------QKRSSALEKELAEFKEVLKMTKKELNEyenrELNLRQDIKNNHLEMDI 1336
Cdd:TIGR00618 496 LLELQE-EPCPLCGScihpnparqdidnpgplTRRMQRGEQTYAQLETSEEDVYHQLTS----ERKQRASLKEQMQEIQQ 570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1337 PVSTLIKKIDDLTA---KLETASSKCLHLGKKNQLLQQelllmrtiqKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQ 1413
Cdd:TIGR00618 571 SFSILTQCDNRSKEdipNLQNITVRLQDLTEKLSEAED---------MLACEQHALLRKLQPEQDLQDVRLHLQQCSQEL 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1414 AQQ---YAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMElrikDLESQLYRMKAQEDfdkiEL 1490
Cdd:TIGR00618 642 ALKltaLHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE----MLAQCQTLLRELET----HI 713
|
650 660 670
....*....|....*....|....*....|....*
gi 568941652 1491 EKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKL 1525
Cdd:TIGR00618 714 EEYDREFNEIENASSSLGSDLAAREDALNQSLKEL 748
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
51-212 |
8.43e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 50.35 E-value: 8.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 51 IHKAASVGDVAKVQHILILGkSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:PHA02874 128 LHYAIKKGDLESIKMLFEYG-ADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACI 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 131 AILLDHG-------------------------------ADPNVMDSSGNTALHYAV-YSENTSMAAKLLAHNANIEAKNK 178
Cdd:PHA02874 207 KLLIDHGnhimnkckngftplhnaiihnrsaiellinnASINDQDIDGSTPLHHAInPPCDIDIIDILLYHKADISIKDN 286
|
170 180 190
....*....|....*....|....*....|....*
gi 568941652 179 DDLTPMLLAVKE-NKQHIVEFLVKKKASIHAVDQL 212
Cdd:PHA02874 287 KGENPIDTAFKYiNKDPVIKDIIANAVLIKEADKL 321
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
52-136 |
8.74e-06 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 50.67 E-value: 8.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 52 HKAASvGDVAKVQhILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAA 131
Cdd:PTZ00322 88 QLAAS-GDAVGAR-ILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQ 165
|
....*
gi 568941652 132 ILLDH 136
Cdd:PTZ00322 166 LLSRH 170
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
98-213 |
9.79e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 50.40 E-value: 9.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 98 TLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDhgADP----NVMDSS---GNTALHYAVYSENTSMAAKLLAHN 170
Cdd:cd22192 35 KLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLME--AAPelvnEPMTSDlyqGETALHIAVVNQNLNLVRELIARG 112
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 568941652 171 ANIEA---------KNKDDLT-----PMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
Cdd:cd22192 113 ADVVSpratgtffrPGPKNLIyygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLG 169
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1001-1219 |
9.89e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 9.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1001 LSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEhmfqdeqGKVSKFMGKQESIEERLAQLQS 1080
Cdd:COG4942 32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALE-------AELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1081 EntlLRQQLDDA-ANKAESKDKTIVNiQDQFQDVLTRFQAeSQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVV 1159
Cdd:COG4942 105 E---LAELLRALyRLGRQPPLALLLS-PEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1160 VRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREA 1219
Cdd:COG4942 180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1084-1529 |
1.13e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1084 LLRQQLDDAANKAESKD-KTIVNIQDQFQDVLTRFQAESQRhslrlEDRNQELVSECSHLRERLCQYENEKAEREVVVRQ 1162
Cdd:COG4717 46 MLLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEK-----EEEYAELQEELEELEEELEELEAELEELREELEK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1163 LQQELADTLKKQSMSEASLEVSS------------RYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHA-EKMEDH 1229
Cdd:COG4717 121 LEKLLQLLPLYQELEALEAELAElperleeleerlEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1230 LQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLE-----CTVDQEQKRSSALEKELAEF-K 1303
Cdd:COG4717 201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLiaaalLALLGLGGSLLSLILTIAGVlF 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1304 EVLKMTKKELNEYENRELNLRQDIKnnhlemDIPVSTLIKKIDDLTAKlETASSKCLHLGKKNQLLQQELLLMRTIQKKC 1383
Cdd:COG4717 281 LVLGLLALLFLLLAREKASLGKEAE------ELQALPALEELEEEELE-ELLAALGLPPDLSPEELLELLDRIEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1384 GKLEKNKKQLEQEVV--NLRSHMEKNMVEhSQAQQYAREVEERARQDLVEKLKQVNLFLQAQA------ASQESLEQLRE 1455
Cdd:COG4717 354 REAEELEEELQLEELeqEIAALLAEAGVE-DEEELRAALEQAEEYQELKEELEELEEQLEELLgeleelLEALDEEELEE 432
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1456 ---------NSNASVRSQMELRIKDLESQLYRMKAQEDFDKIELEKYKQLYQ-----EEFRARKSLSSKLNKTSEKLEEA 1521
Cdd:COG4717 433 eleeleeelEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAElrelaEEWAALKLALELLEEAREEYREE 512
|
....*...
gi 568941652 1522 SSKLLLEE 1529
Cdd:COG4717 513 RLPPVLER 520
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
733-1394 |
1.24e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.21 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 733 ALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEV----EARQQLEASLRTLEMELKTVKSHLNQvLEERNETQRQL--SR 806
Cdd:pfam10174 78 ALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPelteENFRRLQSEHERQAKELFLLRKTLEE-MELRIETQKQTlgAR 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 807 EQNAR----MLQDGILASHLcKQKEIEMTQKKMTSEVSVSH------EKEKDL------LHKNQRLQDEVAVLR-----L 865
Cdd:pfam10174 157 DESIKklleMLQSKGLPKKS-GEEDWERTRRIAEAEMQLGHlevlldQKEKENihlreeLHRRNQLQPDPAKTKalqtvI 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 866 EMDTIKSHNQEKEKRYLEDikianekndnLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDV 945
Cdd:pfam10174 236 EMKDTKISSLERNIRDLED----------EVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESEL 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 946 ESFRSRLasalhdhaeiqtakrdleiafqrardewfrvkDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFhhtkDE 1025
Cdd:pfam10174 306 LALQTKL--------------------------------ETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEV----DA 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1026 LRektLALKHAQRDLSQTQCQMKEVehmfQDEQGKvskfmgkqesieerlaqLQSENTLLRQQLDDAANKAESKDKTIVN 1105
Cdd:pfam10174 350 LR---LRLEEKESFLNKKTKQLQDL----TEEKST-----------------LAGEIRDLKDMLDVKERKINVLQKKIEN 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1106 IQDQFQDvltrfqAESQRHSLRleDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQEladtlkKQSMSEASLEVSS 1185
Cdd:pfam10174 406 LQEQLRD------KDKQLAGLK--ERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQ------REREDRERLEELE 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1186 RYRsnleEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSE 1265
Cdd:pfam10174 472 SLK----KENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1266 EDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVStlikKI 1345
Cdd:pfam10174 548 EAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVA----NI 623
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 568941652 1346 DDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLE 1394
Cdd:pfam10174 624 KHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELD 672
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
916-1233 |
1.48e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 1.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 916 QLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLaSALHDHAEIQTAKRDLEIAfQRARDEWFRVKDKMNFDMSNLR 995
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERR-EALQRLAEYSWDEIDVASA-EREIAELEAELERLDASSDDLA 688
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 996 dnneVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQgkvskfmgkQESIEERL 1075
Cdd:COG4913 689 ----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL---------RALLEERF 755
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1076 AQLQSENTL------LRQQLDDAANKAESKDKTIVNIQDQFQDvltRFQAESQRHSLRLEDrNQELVSECSHL------- 1142
Cdd:COG4913 756 AAALGDAVErelrenLEERIDALRARLNRAEEELERAMRAFNR---EWPAETADLDADLES-LPEYLALLDRLeedglpe 831
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1143 -RERLCQYENEKAEREVVvrQLQQELADTLK--KQSMSE--ASLEVSS---------RYRSNLEEEARDLKKKLGQLRSQ 1208
Cdd:COG4913 832 yEERFKELLNENSIEFVA--DLLSKLRRAIReiKERIDPlnDSLKRIPfgpgrylrlEARPRPDPEVREFRQELRAVTSG 909
|
330 340
....*....|....*....|....*
gi 568941652 1209 LQEARDQHREavHHAEKMEDHLQKL 1233
Cdd:COG4913 910 ASLFDEELSE--ARFAALKRLIERL 932
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1004-1541 |
1.86e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 49.35 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1004 QLSKTERKLNSLEIEFHHTKDELREKTLALKhaqRDLSQTQCQMKEVehmfqdeQGKVSKfMGKQESIEERLAQLQSENT 1083
Cdd:pfam05557 10 RLSQLQNEKKQMELEHKRARIELEKKASALK---RQLDRESDRNQEL-------QKRIRL-LEKREAEAEEALREQAELN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1084 LLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQL 1163
Cdd:pfam05557 79 RLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1164 QQeladtlKKQSMSEAslevssryrsnlEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEkMEDHLQKLElekskfeit 1243
Cdd:pfam05557 159 EK------QQSSLAEA------------EQRIKELEFEIQSQEQDSEIVKNSKSELARIPE-LEKELERLR--------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1244 ikkqsEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELN--------- 1314
Cdd:pfam05557 211 -----EHNKHLNENIENKLLLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRspedlsrri 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1315 -EYENRELNLRQD----------IKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMR------ 1377
Cdd:pfam05557 286 eQLQQREIVLKEEnssltssarqLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRailesy 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1378 ----TIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVE--KLKQVNLFLQAQAASQESLE 1451
Cdd:pfam05557 366 dkelTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERElqALRQQESLADPSYSKEEVDS 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1452 QLRENSNASV-RSQMELRIKDLESQLYRMKAQEDFDkieLEKYKQLY------QEEFRARKSLSSKLNKTSEKLEEASSK 1524
Cdd:pfam05557 446 LRRKLETLELeRQRLREQKNELEMELERRCLQGDYD---PKKTKVLHlsmnpaAEAYQQRKNQLEKLQAEIERLKRLLKK 522
|
570
....*....|....*..
gi 568941652 1525 LLLEEQQNRSLLSTLST 1541
Cdd:pfam05557 523 LEDDLEQVLRLPETTST 539
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
781-1423 |
1.89e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 49.66 E-value: 1.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 781 MELKTVKSHLNQVLEERNETqrqLSREQNARMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEV 860
Cdd:TIGR01612 715 METATVELHLSNIENKKNEL---LDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEI 791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 861 AVL---RLEMDTIKS----HNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTG-------QLNSLKAENTM 926
Cdd:TIGR01612 792 KNHyndQINIDNIKDedakQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINfennckeKIDSEHEQFAE 871
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 927 LSSKLDNEKQNK-----ERLETDVESFRSRLASALH-DHAEIQTAKRdleiafqraRDEWFRVKDKMNFDMSNLRDNNEV 1000
Cdd:TIGR01612 872 LTNKIKAEISDDklndyEKKFNDSKSLINEINKSIEeEYQNINTLKK---------VDEYIKICENTKESIEKFHNKQNI 942
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1001 LSQQLSK---TERKLNSLEIEFHHTKDE-LREKTLALKHAQRDLSqtqcqmkevehmFQDEQGKVSKFMGKQESIEERLA 1076
Cdd:TIGR01612 943 LKEILNKnidTIKESNLIEKSYKDKFDNtLIDKINELDKAFKDAS------------LNDYEAKNNELIKYFNDLKANLG 1010
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1077 QlQSENTLLRQ------QLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRH-SLRLEDRNQELVsecshlrerlcqy 1149
Cdd:TIGR01612 1011 K-NKENMLYHQfdekekATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEiGKNIELLNKEIL------------- 1076
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1150 enEKAEREVVVRQlqqELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDH 1229
Cdd:TIGR01612 1077 --EEAEINITNFN---EIKEKLKHYNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQ 1151
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1230 LQKLE--------------LEKSKFEITIK--KQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKES---------LEcT 1284
Cdd:TIGR01612 1152 INDLEdvadkaisnddpeeIEKKIENIVTKidKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSygknlgklfLE-K 1230
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1285 VDQEQKRSSALEKELAEFKEVLKMTKKELNEYENrELNLRQDIKNNHLEMDIPVS------TLIKKIDDLTAKLEtasSK 1358
Cdd:TIGR01612 1231 IDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIEN-EMGIEMDIKAEMETFNISHDddkdhhIISKKHDENISDIR---EK 1306
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1359 CLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQ---EVVNLRSHMEKNMVEH--SQAQQYAREVEE 1423
Cdd:TIGR01612 1307 SLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLylnEIANIYNILKLNKIKKiiDEVKEYTKEIEE 1376
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
54-213 |
1.90e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 49.19 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 54 AASVGDVaKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVerkceIDARDSEsstalIKAVQCQEEECAAIL 133
Cdd:PHA02874 42 AIRSGDA-KIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLI-----DNGVDTS-----ILPIPCIEKDMIKTI 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 134 LDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
Cdd:PHA02874 111 LDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNG 190
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1289-1542 |
2.11e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1289 QKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNnhlemdipvstLIKKIDDLTAKLETASSKclhlgkknql 1368
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA-----------LERRIAALARRIRALEQE---------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1369 lqqelllMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQE 1448
Cdd:COG4942 78 -------LAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1449 SLEQLRENSNasvrsqmelRIKDLESQLYRMKAQEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLE 1528
Cdd:COG4942 151 QAEELRADLA---------ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
250
....*....|....
gi 568941652 1529 EQQNRSLLSTLSTR 1542
Cdd:COG4942 222 AEELEALIARLEAE 235
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
675-904 |
2.22e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 2.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 675 KRLIELKRSHCELLTGKLK--RMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTS 752
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEeaKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 753 EQlRRKGEQCQSEVEARQQLEASLRTLEMELKTVKsHLNQVLEERNETQRQLSREQNARMLQdgilASHLCKQKEIEmtq 832
Cdd:PTZ00121 1672 ED-KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIK----AEEAKKEAEED--- 1742
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941652 833 KKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTI--KSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEE 904
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVieEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
51-101 |
2.75e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.03 E-value: 2.75e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 568941652 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAYGHPEVVTLLV 101
Cdd:pfam13637 5 LHAAAASGHLELLRLLLEKGAD-INAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1068-1325 |
2.84e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 49.14 E-value: 2.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1068 QESIEERLAQL------QSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVL-TRFQAESQRhslRLEDRNQELVSECS 1140
Cdd:PRK11281 62 QQDLEQTLALLdkidrqKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETrETLSTLSLR---QLESRLAQTLDQLQ 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1141 HLRERLCQYEN---------EKAEREVVVRQLQ-QELADTLKKQSMSEASLEVSSRYRSNLEEEARDLK----KKLGQLR 1206
Cdd:PRK11281 139 NAQNDLAEYNSqlvslqtqpERAQAALYANSQRlQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQndlqRKSLEGN 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1207 SQLQEARDQHREavhhaEKMEdHLQKLElekskfeitikkqsEEIDQLQENLSRVNLsEEDKEKLQKLTELKESLECTVD 1286
Cdd:PRK11281 219 TQLQDLLQKQRD-----YLTA-RIQRLE--------------HQLQLLQEAINSKRL-TLSEKTVQEAQSQDEAARIQAN 277
|
250 260 270
....*....|....*....|....*....|....*....
gi 568941652 1287 QEQKRSSALEKELAEFkeVLKMTKKeLNEYENRELNLRQ 1325
Cdd:PRK11281 278 PLVAQELEINLQLSQR--LLKATEK-LNTLTQQNLRVKN 313
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
95-206 |
2.94e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 48.42 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 95 EVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIE 174
Cdd:PHA02874 105 DMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYAN 184
|
90 100 110
....*....|....*....|....*....|..
gi 568941652 175 AKNKDDLTPMLLAVKENKQHIVEFLVKKKASI 206
Cdd:PHA02874 185 VKDNNGESPLHNAAEYGDYACIKLLIDHGNHI 216
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1061-1325 |
3.38e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.47 E-value: 3.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1061 VSKFMGKQESIEERLAQLQSENTLLR----QQLDDAANKAESKDKTIVNiqdqfqDVLTRFQAESQRHS----LRLEDRN 1132
Cdd:COG3206 73 LSSLSASDSPLETQIEILKSRPVLERvvdkLNLDEDPLGEEASREAAIE------RLRKNLTVEPVKGSnvieISYTSPD 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1133 QEL-------VSEcSHLRERLcqyENEKAEREVVVRQLQQELADTLKKQSMSEASLEvssRYRS-----NLEEEARDLKK 1200
Cdd:COG3206 147 PELaaavanaLAE-AYLEQNL---ELRREEARKALEFLEEQLPELRKELEEAEAALE---EFRQknglvDLSEEAKLLLQ 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1201 KLGQLRSQLQEARDQHREAVHHAEKMEDhlqklELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKE--------KLQ 1272
Cdd:COG3206 220 QLSELESQLAEARAELAEAEARLAALRA-----QLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSarytpnhpDVI 294
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 568941652 1273 KLTELKESLECTVDQEQKRS-SALEKELAEFKEVLKMTKKELNEYENRELNLRQ 1325
Cdd:COG3206 295 ALRAQIAALRAQLQQEAQRIlASLEAELEALQAREASLQAQLAQLEARLAELPE 348
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
82-111 |
3.62e-05 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 42.28 E-value: 3.62e-05
10 20 30
....*....|....*....|....*....|.
gi 568941652 82 RTALHLACA-YGHPEVVTLLVERKCEIDARD 111
Cdd:pfam00023 3 NTPLHLAAGrRGNLEIVKLLLSKGADVNARD 33
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
651-1079 |
5.39e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.14 E-value: 5.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 651 IEHLRLECKD----TASLLKIRDAVYSYKRLIELKRSHCELLTG---KLKRMENKYKGLQKEMSETEEVKSRLEH---EK 720
Cdd:PRK03918 268 IEELKKEIEEleekVKELKELKEKAEEYIKLSEFYEEYLDELREiekRLSRLEEEINGIEERIKELEEKEERLEElkkKL 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 721 VGWEQELCRLR-------FALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQV 793
Cdd:PRK03918 348 KELEKRLEELEerhelyeEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 794 LEERNETQ-------RQLSREQNARmlqdgILASHLCKQKEIEMTQKKMTSEVSvSHEKEKDLLHKNQRLQDEVAVLRLE 866
Cdd:PRK03918 428 IEELKKAKgkcpvcgRELTEEHRKE-----LLEEYTAELKRIEKELKEIEEKER-KLRKELRELEKVLKKESELIKLKEL 501
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 867 MDTIKSHNQEKEKRYLEDIKIANEKNDNL-QRMVKLNEEtfTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLET-- 943
Cdd:PRK03918 502 AEQLKELEEKLKKYNLEELEKKAEEYEKLkEKLIKLKGE--IKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKel 579
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 944 ---------DVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEwfRVKDKMNFDMSNLRDNN-EVLSQQLSKTERKLN 1013
Cdd:PRK03918 580 eelgfesveELEERLKELEPFYNEYLELKDAEKELEREEKELKKL--EEELDKAFEELAETEKRlEELRKELEELEKKYS 657
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941652 1014 slEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQD---EQGKVSKFMGKQESIEERLAQLQ 1079
Cdd:PRK03918 658 --EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKlkeELEEREKAKKELEKLEKALERVE 724
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1000-1500 |
5.41e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.89 E-value: 5.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1000 VLSQQLSKTERKLNSLEIEFHHTKDELRektlalkhAQRDLSQTqcqmkeVEHMFQDEQGKVSKFMGKQESIEERLAQLQ 1079
Cdd:pfam10174 57 VLKEQYRVTQEENQHLQLTIQALQDELR--------AQRDLNQL------LQQDFTTSPVDGEDKFSTPELTEENFRRLQ 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1080 S-------ENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLED-----RNQELVSECSHLRERLC 1147
Cdd:pfam10174 123 SeherqakELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKGLPKKSGEEDwertrRIAEAEMQLGHLEVLLD 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1148 QYENEKAE-REVVVR--QLQQELADTLKKQSMseasLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAE 1224
Cdd:pfam10174 203 QKEKENIHlREELHRrnQLQPDPAKTKALQTV----IEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQME 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1225 KMEDH--LQKLELEKSKFEITiKKQSEeIDQLQENLSRVNLSEEDKEklQKLTELKESLECtvdqEQKRSSALEKELAEF 1302
Cdd:pfam10174 279 VYKSHskFMKNKIDQLKQELS-KKESE-LLALQTKLETLTNQNSDCK--QHIEVLKESLTA----KEQRAAILQTEVDAL 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1303 KEVLKMTKKELNEYENRELNLRQDiknnhlemdipVSTLIKKIDDLTAKLETASSKCLHLGKKnqlLQQELLLMRTIQKK 1382
Cdd:pfam10174 351 RLRLEEKESFLNKKTKQLQDLTEE-----------KSTLAGEIRDLKDMLDVKERKINVLQKK---IENLQEQLRDKDKQ 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1383 CGKLEKNKKQLEQEVVNLRSH---MEKNMVEHS---QAQQYAREVEERARQDLVEKLKQVNL-------FLQAQAASQE- 1448
Cdd:pfam10174 417 LAGLKERVKSLQTDSSNTDTAlttLEEALSEKEriiERLKEQREREDRERLEELESLKKENKdlkekvsALQPELTEKEs 496
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 568941652 1449 SLEQLRE--NSNASVRSQMELRIKDLESQLYRMKaqEDFDKIELEKYKQLYQEE 1500
Cdd:pfam10174 497 SLIDLKEhaSSLASSGLKKDSKLKSLEIAVEQKK--EECSKLENQLKKAHNAEE 548
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
698-1307 |
7.13e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.91 E-value: 7.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 698 KYKGLQKEMSETEEVKSRLEHEKVGWEQElcRLRFALKQEEEKRRSADQlsektSEQLRRKGEQCQSEV-EARQQL---E 773
Cdd:pfam12128 242 EFTKLQQEFNTLESAELRLSHLHFGYKSD--ETLIASRQEERQETSAEL-----NQLLRTLDDQWKEKRdELNGELsaaD 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 774 ASLRTLEMELKTVKSHLNQVLEERNET----QRQLSREQNARMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDL 849
Cdd:pfam12128 315 AAVAKDRSELEALEDQHGAFLDADIETaaadQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAG 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 850 LHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSS 929
Cdd:pfam12128 395 IKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 930 KLDNEKQ----NKERLETDVESFRSRLASALHDH-------AEIQTAKRDLE----------IAFQRA-----RDEWFRV 983
Cdd:pfam12128 475 RAREEQEaanaEVERLQSELRQARKRRDQASEALrqasrrlEERQSALDELElqlfpqagtlLHFLRKeapdwEQSIGKV 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 984 KDKMNFDMSNL--RDNNEVLSQQLSKTERKLNSLEI---EFHHTKDELREKTLALKHAQRDLSQTQCQMKEvehmfqdEQ 1058
Cdd:pfam12128 555 ISPELLHRTDLdpEVWDGSVGGELNLYGVKLDLKRIdvpEWAASEEELRERLDKAEEALQSAREKQAAAEE-------QL 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1059 GKVSKFMGKQESIEERLAQL--QSENTLLR-----QQLDDAANKA--ESKDKTIVNIQD----------QFQDVLTRFQA 1119
Cdd:pfam12128 628 VQANGELEKASREETFARTAlkNARLDLRRlfdekQSEKDKKNKAlaERKDSANERLNSleaqlkqldkKHQAWLEEQKE 707
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1120 ESQRHSLRLEDRNQELVSECSHLRERLCQ-YENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLE---EEA 1195
Cdd:pfam12128 708 QKREARTEKQAYWQVVEGALDAQLALLKAaIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLErkiERI 787
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1196 RDLKKKLGQLRSQLQEARDQHREAV--------HHAEKMEDHL-----------QKLELEKSKFEITIKKQSEEIDQLQE 1256
Cdd:pfam12128 788 AVRRQEVLRYFDWYQETWLQRRPRLatqlsnieRAISELQQQLarliadtklrrAKLEMERKASEKQQVRLSENLRGLRC 867
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 568941652 1257 NLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKR---SSALEKELAEFKEVLK 1307
Cdd:pfam12128 868 EMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKRdylSESVKKYVEHFKNVIA 921
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1191-1358 |
7.37e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.07 E-value: 7.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1191 LEEEARDLKKKLGQLRSQLQEARDQHreavhhaEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEdkek 1270
Cdd:COG1579 22 LEHRLKELPAELAELEDELAALEARL-------EAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE---- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1271 LQKLTELKESLEctvdqeqKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVSTLIKKIDDLTA 1350
Cdd:COG1579 91 YEALQKEIESLK-------RRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163
|
....*...
gi 568941652 1351 KLETASSK 1358
Cdd:COG1579 164 EREELAAK 171
|
|
| TRPV3 |
cd22194 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ... |
80-207 |
7.62e-05 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a temperature-sensitive Transient Receptor Potential (TRP) ion channel that is activated by warm temperatures, synthetic small-molecule chemicals, and natural compounds from plants. TRPV3 function is regulated by physiological factors such as extracellular divalent cations and acidic pH, intracellular adenosine triphosphate, membrane voltage, and arachidonic acid. It is expressed in both neuronal and non-neuronal tissues including epidermal keratinocytes, epithelial cells in the gut, endothelial cells in blood vessels, and neurons in dorsal root ganglia and CNS. TRPV3 null mice have abnormal hair morphogenesis and compromised skin barrier function. It may play roles in inflammatory skin disorders, such as itch and pain sensation. TRPV3 is also expressed by many neuronal and non-neuronal tissues, showing that TRPV3 might play roles in other unknown cellular and physiological functions. TRPV3 belongs to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.
Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 47.45 E-value: 7.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 80 KDRTALHLACAYGHPEVVTLLVERKCEIDARDSE--------------SSTALIKAVQCQEEECAAILLDHGADPNVM-D 144
Cdd:cd22194 140 EGQTALNIAIERRQGDIVKLLIAKGADVNAHAKGvffnpkykhegfyfGETPLALAACTNQPEIVQLLMEKESTDITSqD 219
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941652 145 SSGNTALHYAVY----SEN-----TSMAAKLL--AHNANIEA-KNKDDLTPMLLAVKENK----QHIVEFLVKKKASIH 207
Cdd:cd22194 220 SRGNTVLHALVTvaedSKTqndfvKRMYDMILlkSENKNLETiRNNEGLTPLQLAAKMGKaeilKYILSREIKEKPNRS 298
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1238-1540 |
7.77e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 7.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1238 SKFEITIKKQSEEIDQLQENLSRVNLSE--------------EDKEKLQKLTELKESLECTVDQEQKRS-----SALEKE 1298
Cdd:TIGR02169 166 AEFDRKKEKALEELEEVEENIERLDLIIdekrqqlerlrrerEKAERYQALLKEKREYEGYELLKEKEAlerqkEAIERQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1299 LAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVS----TLIKKIDDLTAKLETASSKclhLGKKNQLLQQELL 1374
Cdd:TIGR02169 246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERS---IAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1375 LMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQaqqyAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLR 1454
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE----LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1455 ENSNASVRSQMEL--RIKDLESQLYRMKAqedfdkiELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQN 1532
Cdd:TIGR02169 399 REINELKRELDRLqeELQRLSEELADLNA-------AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471
|
....*...
gi 568941652 1533 RSLLSTLS 1540
Cdd:TIGR02169 472 YDLKEEYD 479
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
699-1444 |
9.74e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.53 E-value: 9.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 699 YKGLQKEMSETEEVKSRLEHEKVGwEQELCRLRFALKQEEekRRSADQLsektseqlrrkgEQCQsevEARQQLEASLRT 778
Cdd:pfam12128 233 IAGIMKIRPEFTKLQQEFNTLESA-ELRLSHLHFGYKSDE--TLIASRQ------------EERQ---ETSAELNQLLRT 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 779 LEMELKTVKSHLNQVLE------ERNETQRQLSREQNARMLQDGILASHLCKQKEiemtqKKMTSEVSVSHEKEKDLLHK 852
Cdd:pfam12128 295 LDDQWKEKRDELNGELSaadaavAKDRSELEALEDQHGAFLDADIETAAADQEQL-----PSWQSELENLEERLKALTGK 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 853 NQRLQDEVAVLRLEMDtikshnqEKEKRYLEDIkiaNEKNDNlQRMVKLNEETFTKTIFQytGQLNSLKAEntmLSSKLD 932
Cdd:pfam12128 370 HQDVTAKYNRRRSKIK-------EQNNRDIAGI---KDKLAK-IREARDRQLAVAEDDLQ--ALESELREQ---LEAGKL 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 933 NEKQNKERLETDVESFRSRLASALHDhAEIQTAKRDLEIAFQRARDEwfrvkdkmnfdmsnlrdnnevlsqqLSKTERKL 1012
Cdd:pfam12128 434 EFNEEEYRLKSRLGELKLRLNQATAT-PELLLQLENFDERIERAREE-------------------------QEAANAEV 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1013 NSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESI-EERLAQLQSENTLLRQQLDD 1091
Cdd:pfam12128 488 ERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLHRTDLDP 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1092 AANKAESKDktivniQDQFQDVLTRFQAESQRHSLRLEDRnqelvsecshLRERLCQYENEKAEREVVVRQLQQELADTL 1171
Cdd:pfam12128 568 EVWDGSVGG------ELNLYGVKLDLKRIDVPEWAASEEE----------LRERLDKAEEALQSAREKQAAAEEQLVQAN 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1172 KKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHReavhhaEKMEDHLQKLELEKSKFEITIKKQSEEI 1251
Cdd:pfam12128 632 GELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERK------DSANERLNSLEAQLKQLDKKHQAWLEEQ 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1252 -DQLQENlsrvnlSEEDKEKLQKLTELKESLECTVDQE-QKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKN 1329
Cdd:pfam12128 706 kEQKREA------RTEKQAYWQVVEGALDAQLALLKAAiAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRT 779
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1330 NHLEM--------------DIPVSTLIKKIDDLTAKLETASSKCLHL-GKKNQLLQQELLLMRTIQKKCGKLEKNKKQLE 1394
Cdd:pfam12128 780 LERKIeriavrrqevlryfDWYQETWLQRRPRLATQLSNIERAISELqQQLARLIADTKLRRAKLEMERKASEKQQVRLS 859
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 568941652 1395 QEVVNLRSHMEK--NMVEHSQAQQYAREVEERARQdlVEKLKQVNLFLQAQA 1444
Cdd:pfam12128 860 ENLRGLRCEMSKlaTLKEDANSEQAQGSIGERLAQ--LEDLKLKRDYLSESV 909
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
675-1347 |
1.14e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.06 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 675 KRLIELKRSHCELLTGKLKRMENKYKGlQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQL---SEKT 751
Cdd:PTZ00121 1212 RKAEEARKAEDAKKAEAVKKAEEAKKD-AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkkaEEKK 1290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 752 SEQLRRKGEQCQSEVEARQQLEASLRTleMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMT 831
Cdd:PTZ00121 1291 KADEAKKAEEKKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 832 QKKMTSEVSVSHE---KEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKE-----KRYLEDIKIANEKNDNLQRMVKLnE 903
Cdd:PTZ00121 1369 AEKKKEEAKKKADaakKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKkadeaKKKAEEKKKADEAKKKAEEAKKA-D 1447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 904 ETFTKTIFQYTGQLNSLKAENTMLSSKLDN---EKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEW 980
Cdd:PTZ00121 1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA 1527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 981 FRVKDKMNFDmsNLRDNNEVL-SQQLSKTERKLNSLEI-EFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQ 1058
Cdd:PTZ00121 1528 KKAEEAKKAD--EAKKAEEKKkADELKKAEELKKAEEKkKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1059 GKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTivnIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSE 1138
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKA---EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK 1682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1139 CSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARD-QHR 1217
Cdd:PTZ00121 1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKiAHL 1762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1218 EAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENL--SRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSAL 1295
Cdd:PTZ00121 1763 KKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ 1842
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 568941652 1296 EKELAEFKEVLKMTKKELNEYENRELNLRQDIKN-NHLEMDIPVSTLIKKIDD 1347
Cdd:PTZ00121 1843 LEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLkEDDEEEIEEADEIEKIDK 1895
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
838-1260 |
1.37e-04 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 46.61 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 838 EVSVSHEKEKDLLHKNQRLQDEVAVLrlemdtikshnQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKtIFQYTGQL 917
Cdd:pfam05622 1 DLSEAQEEKDELAQRCHELDQQVSLL-----------QEEKNSLQQENKKLQERLDQLESGDDSGTPGGKK-YLLLQKQL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 918 NSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIaFQRARDEWFRV-------KDKMNfD 990
Cdd:pfam05622 69 EQLQEENFRLETARDDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDI-LRESSDKVKKLeatvetyKKKLE-D 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 991 MSNLRdnNEVLSQQLSKTERKLNSLEIEfhhtkDELReKTLALKhAQRDLSQTQCQmkEVEHMFQDEQGKVSKFMGKQES 1070
Cdd:pfam05622 147 LGDLR--RQVKLLEERNAEYMQRTLQLE-----EELK-KANALR-GQLETYKRQVQ--ELHGKLSEESKKADKLEFEYKK 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1071 IEERLAQLQSENTLLRQQLDdaANKAESKDKTIVNIQdqfQDVLTRFQAESQRHSLRLEDRNQELVSecSHLRERLcqye 1150
Cdd:pfam05622 216 LEEKLEALQKEKERLIIERD--TLRETNEELRCAQLQ---QAELSQADALLSPSSDPGDNLAAEIMP--AEIREKL---- 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1151 nEKAEREVVVRQLQQELADTlKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAE------ 1224
Cdd:pfam05622 285 -IRLQHENKMLRLGQEGSYR-ERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEdssllk 362
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 568941652 1225 -KMEDHLQKL-----ELEKSKFEITIKKQ------SEEIDQLQENLSR 1260
Cdd:pfam05622 363 qKLEEHLEKLheaqsELQKKKEQIEELEPkqdsnlAQKIDELQEALRK 410
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
939-1316 |
1.50e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.43 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 939 ERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEI- 1017
Cdd:pfam07888 30 ELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAs 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1018 --EFHHTKDELREKTLALKHAQRDLSQ------TQCQMKEVEHMFQDEQGKVSKFMGKQESIEER-----LAQLQSENTL 1084
Cdd:pfam07888 110 seELSEEKDALLAQRAAHEARIRELEEdiktltQRVLERETELERMKERAKKAGAQRKEEEAERKqlqakLQQTEEELRS 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1085 LRQQLDDAANKAESKDKTIVNIQDQFQdVLTRFQAESQRHSLRLEDRNQELVSecshLRERLCQYENEkaerevvVRQLQ 1164
Cdd:pfam07888 190 LSKEFQELRNSLAQRDTQVLQLQDTIT-TLTQKLTTAHRKEAENEALLEELRS----LQERLNASERK-------VEGLG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1165 QELADTLKKQSMSEASLevssrYRSNLeeEARDLKKKLGQLRSQLQEAR---DQHREAVHH-AEKMEDHLQKLELEKSKF 1240
Cdd:pfam07888 258 EELSSMAAQRDRTQAEL-----HQARL--QAAQLTLQLADASLALREGRarwAQERETLQQsAEADKDRIEKLSAELQRL 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1241 EITIKKQSEEIDQLQENL------SRVNLSEEDKEklqkLTELKESLEctvdqeqkrssALEKElaefKEVLKMTKKELN 1314
Cdd:pfam07888 331 EERLQEERMEREKLEVELgrekdcNRVQLSESRRE----LQELKASLR-----------VAQKE----KEQLQAEKQELL 391
|
..
gi 568941652 1315 EY 1316
Cdd:pfam07888 392 EY 393
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
147-178 |
1.69e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 40.35 E-value: 1.69e-04
10 20 30
....*....|....*....|....*....|...
gi 568941652 147 GNTALHYAVYSE-NTSMAAKLLAHNANIEAKNK 178
Cdd:pfam00023 2 GNTPLHLAAGRRgNLEIVKLLLSKGADVNARDK 34
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1145-1306 |
2.45e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.53 E-value: 2.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1145 RLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQhREavhhAE 1224
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNN-KE----YE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1225 KMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvnLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKE 1304
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAE--LEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAA 170
|
..
gi 568941652 1305 VL 1306
Cdd:COG1579 171 KI 172
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
887-1307 |
2.80e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 45.72 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 887 IANEKNDNLQRMVKLNEETFTKTifqytGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASAlhdhaeiQTAK 966
Cdd:PRK04863 277 HANERRVHLEEALELRRELYTSR-----RQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLV-------QTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 967 RDLEiAFQRARDEWfrvkDKMNFdmsNLRDNNEVL---SQQLSKTERKLNSLEIEFHHTK----------DELREKTLAL 1033
Cdd:PRK04863 345 RQQE-KIERYQADL----EELEE---RLEEQNEVVeeaDEQQEENEARAEAAEEEVDELKsqladyqqalDVQQTRAIQY 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1034 KHAQRDL--SQTQCQMKEVEhmfqdeqgkvskfmgkQESIEERLAQLQSENTLLRQQLDDAANKAESKDktivNIQDQFQ 1111
Cdd:PRK04863 417 QQAVQALerAKQLCGLPDLT----------------ADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQ----AAHSQFE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1112 dvltrfQAESQRHSLRLE-DRNQELvsecSHLRERLCQYENEK--AEREVVVRQLQQELADTLKKQSMSEASL-EVSSRY 1187
Cdd:PRK04863 477 ------QAYQLVRKIAGEvSRSEAW----DVARELLRRLREQRhlAEQLQQLRMRLSELEQRLRQQQRAERLLaEFCKRL 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1188 RSNLEEEArDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEitikKQSEEIDQLQENLSRVN-LSEE 1266
Cdd:PRK04863 547 GKNLDDED-ELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLA----ARAPAWLAAQDALARLReQSGE 621
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 568941652 1267 DKEKLQKLTELKESLectvdQEQKRSSALEK-ELAEFKEVLK 1307
Cdd:PRK04863 622 EFEDSQDVTEYMQQL-----LERERELTVERdELAARKQALD 658
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1033-1219 |
2.87e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 2.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1033 LKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESK----DKTIVNIQ- 1107
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERreelGERARALYr 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1108 --------------DQFQDVLTRFQAESqrhslRLEDRNQELVSECSHLRERLcqyENEKAEREVVVRQLQQELADTLKK 1173
Cdd:COG3883 98 sggsvsyldvllgsESFSDFLDRLSALS-----KIADADADLLEELKADKAEL---EAKKAELEAKLAELEALKAELEAA 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568941652 1174 QSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREA 1219
Cdd:COG3883 170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
82-109 |
3.53e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 39.16 E-value: 3.53e-04
10 20
....*....|....*....|....*...
gi 568941652 82 RTALHLACAYGHPEVVTLLVERKCEIDA 109
Cdd:pfam13606 3 NTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
844-1304 |
4.16e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 4.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 844 EKEKDLLHKNQRLQDEVAVLRLEMDTIKSHN-QEKEKRYLEDIKIANEKNDNLQRmVKLNEETFTKTIFQYTGQLNSLKA 922
Cdd:COG4717 52 EKEADELFKPQGRKPELNLKELKELEEELKEaEEKEEEYAELQEELEELEEELEE-LEAELEELREELEKLEKLLQLLPL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 923 ENTM--LSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRvkdkmnfDMSNLRDNNEV 1000
Cdd:COG4717 131 YQELeaLEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEE-------ELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1001 LSQQLSKTERKLNSLEIEFHHTKDELR--EKTLALKHAQRDLSQTQCQMK------EVEHMFQDEQGKVSKFMGKQESIE 1072
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEqlENELEAAALEERLKEARLLLLiaaallALLGLGGSLLSLILTIAGVLFLVL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1073 ERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAEsqrhslrlEDRNQELVSECSHLRERLCQYENE 1152
Cdd:COG4717 284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLP--------PDLSPEELLELLDRIEELQELLRE 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1153 KAEREvvvRQLQQELADTLKKQSMSEASLEVSSRYRSNLE--EEARDLKKKLGQLRSQLQEARD--QHREAVHHAEKMED 1228
Cdd:COG4717 356 AEELE---EELQLEELEQEIAALLAEAGVEDEEELRAALEqaEEYQELKEELEELEEQLEELLGelEELLEALDEEELEE 432
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941652 1229 HLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSA---LEKELAEFKE 1304
Cdd:COG4717 433 ELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLAlelLEEAREEYRE 511
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1182-1315 |
4.54e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 45.07 E-value: 4.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1182 EVSSRYR---SNLEEEARDLKKKLGQLRSQLQEA-RDQHREAVHHAEKMEDHLQKLElekskfeitikkqsEEIDQLQEN 1257
Cdd:COG0542 397 EAAARVRmeiDSKPEELDELERRLEQLEIEKEALkKEQDEASFERLAELRDELAELE--------------EELEALKAR 462
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 1258 LsrvnlsEEDKEKLQKLTELKESLEctvdQEQKRSSALEKELAEFKEVLKMTKKELNE 1315
Cdd:COG0542 463 W------EAEKELIEEIQELKEELE----QRYGKIPELEKELAELEEELAELAPLLRE 510
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1024-1215 |
4.80e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.95 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1024 DELREKTLALKHAQRDLSQTQCQMKEV----EHM-FQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAES 1098
Cdd:PRK04863 938 EQLKQDYQQAQQTQRDAKQQAFALTEVvqrrAHFsYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQ 1017
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1099 KDKTivniqdqFQDVLTRFQAESQRHslrledrnQELVSECSHLRERLCQYENEKAerevvvRQLQQELADTLKKQSMSE 1178
Cdd:PRK04863 1018 YNQV-------LASLKSSYDAKRQML--------QELKQELQDLGVPADSGAEERA------RARRDELHARLSANRSRR 1076
|
170 180 190
....*....|....*....|....*....|....*..
gi 568941652 1179 ASLEvssRYRSNLEEEARDLKKKLGQLRSQLQEARDQ 1215
Cdd:PRK04863 1077 NQLE---KQLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
80-109 |
5.32e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.72 E-value: 5.32e-04
10 20 30
....*....|....*....|....*....|
gi 568941652 80 KDRTALHLACAYGHPEVVTLLVERKCEIDA 109
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
960-1213 |
5.77e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 5.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 960 AEIQTAKRDLEIAFQRARDewFRVKDkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEfhhtkdeLREKTLALKHAQRD 1039
Cdd:COG3206 182 EQLPELRKELEEAEAALEE--FRQKN----GLVDLSEEAKLLLQQLSELESQLAEARAE-------LAEAEARLAALRAQ 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1040 LSQTQCQMKEVehmfqdeqgkvskfmgkqeSIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQA 1119
Cdd:COG3206 249 LGSGPDALPEL-------------------LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1120 ESQRhslrledrnqelvsecshlreRLCQYENEKAEREVVVRQLQQELADtLKKQSMSEASLEVssRYRsNLEEEARDLK 1199
Cdd:COG3206 310 EAQR---------------------ILASLEAELEALQAREASLQAQLAQ-LEARLAELPELEA--ELR-RLEREVEVAR 364
|
250
....*....|....
gi 568941652 1200 KKLGQLRSQLQEAR 1213
Cdd:COG3206 365 ELYESLLQRLEEAR 378
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1032-1239 |
6.34e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 6.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1032 ALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQ-------LQSENTLLRQQLDDAANKAESKDKTIV 1104
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlarriraLEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1105 NIQDQFQDVLTRFQAESQRHSLRL----ED-----RNQELVSECS-HLRERLCQYENEKAEREVVVRQLQQE---LADTL 1171
Cdd:COG4942 101 AQKEELAELLRALYRLGRQPPLALllspEDfldavRRLQYLKYLApARREQAEELRADLAELAALRAELEAEraeLEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941652 1172 KKQsmseaslevsSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSK 1239
Cdd:COG4942 181 AEL----------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1003-1521 |
8.07e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.14 E-value: 8.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1003 QQLSKTERKLNSLEiefhhtkdELREKTLALKHAQRDLSQTQcQMKEVEHMFQDEQgKVSKFMGKQESIEERLAQLQSEN 1082
Cdd:COG4913 242 EALEDAREQIELLE--------PIRELAERYAAARERLAELE-YLRAALRLWFAQR-RLELLEAELEELRAELARLEAEL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1083 TLLRQQLDDAAnkaESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQElvsecshlRERLcqyenekaerEVVVRQ 1162
Cdd:COG4913 312 ERLEARLDALR---EELDELEAQIRGNGGDRLEQLEREIERLERELEERERR--------RARL----------EALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1163 LQQELADT----LKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKL----- 1233
Cdd:COG4913 371 LGLPLPASaeefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALrdala 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1234 -ELEKSKFE-------ITIKKQSEE----------------------IDQLQENLSRVNLS--------EEDKEKLQKLT 1275
Cdd:COG4913 451 eALGLDEAElpfvgelIEVRPEEERwrgaiervlggfaltllvppehYAAALRWVNRLHLRgrlvyervRTGLPDPERPR 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1276 ELKESLECTVD-QEQKRSSALEKELAEFKEVLK------------------MTKkelNEYENRELNLRQDIKNNHLemdI 1336
Cdd:COG4913 531 LDPDSLAGKLDfKPHPFRAWLEAELGRRFDYVCvdspeelrrhpraitragQVK---GNGTRHEKDDRRRIRSRYV---L 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1337 PVSTlIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKL------EKNKKQLEQEVVNL---RSHMEKN 1407
Cdd:COG4913 605 GFDN-RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLaeyswdEIDVASAEREIAELeaeLERLDAS 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1408 MVEHSQAQQYAREVEERaRQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQLYRMKAQEDFDK 1487
Cdd:COG4913 684 SDDLAALEEQLEELEAE-LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762
|
570 580 590
....*....|....*....|....*....|....
gi 568941652 1488 IELEKYKQLYQEefraRKSLSSKLNKTSEKLEEA 1521
Cdd:COG4913 763 VERELRENLEER----IDALRARLNRAEEELERA 792
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1194-1477 |
9.55e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.12 E-value: 9.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1194 EARDLKKKLGQLRSQLQEARDQHREAVH---HAEKMEDHLQKLELEKSKFEIT----IKKQSEEIDQLQ-ENLSRVNLSE 1265
Cdd:PLN02939 164 EKEALQGKINILEMRLSETDARIKLAAQekiHVEILEEQLEKLRNELLIRGATeglcVHSLSKELDVLKeENMLLKDDIQ 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1266 EDKEKLQKLTELKESLectvdqeqkrsSALEKELAEFKEVLKmtkkelnEYENRELNLRQDI-KNNHLEMDIpvstLIKK 1344
Cdd:PLN02939 244 FLKAELIEVAETEERV-----------FKLEKERSLLDASLR-------ELESKFIVAQEDVsKLSPLQYDC----WWEK 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1345 IDDLTAKLETASSKCLHlgkknqlLQQELLLMRTIQKKCGKLEKNKKqlEQEVVNLRSHMEKNMvehsqaQQYAREVEER 1424
Cdd:PLN02939 302 VENLQDLLDRATNQVEK-------AALVLDQNQDLRDKVDKLEASLK--EANVSKFSSYKVELL------QQKLKLLEER 366
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 568941652 1425 ARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNasvRSQMELRIKDLESQLY 1477
Cdd:PLN02939 367 LQASDHEIHSYIQLYQESIKEFQDTLSKLKEESK---KRSLEHPADDMPSEFW 416
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
688-1282 |
9.59e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.01 E-value: 9.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 688 LTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQE-------EEKRRSADQLSEKTSEQLRRKGE 760
Cdd:pfam01576 487 LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDagtlealEEGKKRLQRELEALTQQLEEKAA 566
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 761 QCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQN--ARMLQDGILASHLCKQKEiemtqkkmTSE 838
Cdd:pfam01576 567 AYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAisARYAEERDRAEAEAREKE--------TRA 638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 839 VSVSHEKEKDLLHKNQrLQDEVAVLRLEMDTIKS---------HNQEKEKRYLEdiKIANEKNDNLQRMV-KLNEETFTK 908
Cdd:pfam01576 639 LSLARALEEALEAKEE-LERTNKQLRAEMEDLVSskddvgknvHELERSKRALE--QQVEEMKTQLEELEdELQATEDAK 715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 909 TIFQYTGQlnSLKAENTMLSSKLDNEKQNKER--------LETDVESFRSRLASALHDHAEIQTAKRDLEI---AFQRAR 977
Cdd:pfam01576 716 LRLEVNMQ--ALKAQFERDLQARDEQGEEKRRqlvkqvreLEAELEDERKQRAQAVAAKKKLELDLKELEAqidAANKGR 793
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 978 DEWFRVKDKMNFDMSNL-------RDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQcqmkev 1050
Cdd:pfam01576 794 EEAVKQLKKLQAQMKDLqreleeaRASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELA------ 867
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1051 EHMFQDEQGKVSKFMGKQEsIEERLAQLQSEntllrqqLDDAANKAESKDKTIVNIQDQFQDVLTRFQAEsQRHSLRLED 1130
Cdd:pfam01576 868 DEIASGASGKSALQDEKRR-LEARIAQLEEE-------LEEEQSNTELLNDRLRKSTLQVEQLTTELAAE-RSTSQKSES 938
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1131 RNQELVSECSHLRERLcqyenekAEREVVVRQLQQELADTLK-KQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQL 1209
Cdd:pfam01576 939 ARQQLERQNKELKAKL-------QEMEGTVKSKFKSSIAALEaKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQV 1011
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941652 1210 QEARdqhreavHHAEKMEDHLQKLELEKSKfeitIKKQSEEIdqlQENLSRVNLSeedKEKLQK-LTELKESLE 1282
Cdd:pfam01576 1012 EDER-------RHADQYKDQAEKGNSRMKQ----LKRQLEEA---EEEASRANAA---RRKLQReLDDATESNE 1068
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
740-1097 |
9.87e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 9.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 740 KRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELK---TVKSHLNQVLEERNETQRQLSREQNARMLQDg 816
Cdd:pfam17380 286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDrqaAIYAEQERMAMERERELERIRQEERKRELER- 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 817 ilashlCKQKEIEMTQKKMTSEVSVSHEKEKdllhKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQ 896
Cdd:pfam17380 365 ------IRQEEIAMEISRMRELERLQMERQQ----KNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 897 RMVKLNEETFTKTIFQYtgQLNSLKAENTMLSSKLDNEKQNKERLETDVESfrsrlasalHDHAEIQTAKRDLeiafqra 976
Cdd:pfam17380 435 REVRRLEEERAREMERV--RLEEQERQQQVERLRQQEEERKRKKLELEKEK---------RDRKRAEEQRRKI------- 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 977 rdewfrvkdkmnfdmsnLRDNNEVLSQQLSKTERKLNSLEIEFhhtkdELREKTLALKHAQRDLSQTQCQMKEVEhmfqd 1056
Cdd:pfam17380 497 -----------------LEKELEERKQAMIEEERKRKLLEKEM-----EERQKAIYEEERRREAEEERRKQQEME----- 549
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 568941652 1057 EQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAE 1097
Cdd:pfam17380 550 ERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAE 590
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
952-1215 |
9.94e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 9.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 952 LASALHDHAEIQTAKRDLEiAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTL 1031
Cdd:COG4942 12 ALAAAAQADAAAEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1032 ALKHAQRDLSQTQCQMKevehmfqdEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAeskdktivnIQDQFQ 1111
Cdd:COG4942 91 EIAELRAELEAQKEELA--------ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA---------RREQAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1112 DvLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQsmseaslevssryrSNL 1191
Cdd:COG4942 154 E-LRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL--------------AEL 218
|
250 260
....*....|....*....|....
gi 568941652 1192 EEEARDLKKKLGQLRSQLQEARDQ 1215
Cdd:COG4942 219 QQEAEELEALIARLEAEAAAAAER 242
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
1002-1276 |
1.11e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 43.69 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1002 SQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQgkvskFMGKQESIEERLAQlqSE 1081
Cdd:pfam06160 178 REVLEKLEEETDALEELMEDIPPLYEELKTELPDQLEELKEGYREMEEEGYALEHLN-----VDKEIQQLEEQLEE--NL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1082 NTLLRQQLDDAANKAESKDKTIVNIQDQF-------QDVLTRfQAESQRHSLRLEDRNQELVSECSHLR----------E 1144
Cdd:pfam06160 251 ALLENLELDEAEEALEEIEERIDQLYDLLekevdakKYVEKN-LPEIEDYLEHAEEQNKELKEELERVQqsytlnenelE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1145 RLCQYENEKAEREVVVRQLQQELADtlKKQSMSEASLEVSSRYRS--NLEEEARDLKKKLGQLRSQLQEARDQhreavhh 1222
Cdd:pfam06160 330 RVRGLEKQLEELEKRYDEIVERLEE--KEVAYSELQEELEEILEQleEIEEEQEEFKESLQSLRKDELEAREK------- 400
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941652 1223 AEKMEDHLQ--KLELEKSK-------FEITIKKQSEEIDQLQENLSR-----------VNLSEEDKEKLQKLTE 1276
Cdd:pfam06160 401 LDEFKLELReiKRLVEKSNlpglpesYLDYFFDVSDEIEDLADELNEvplnmdevnrlLDEAQDDVDTLYEKTE 474
|
|
| TMCO5 |
pfam14992 |
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing ... |
1192-1276 |
1.19e-03 |
|
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing proteins 5A and 5B.
Pssm-ID: 464427 [Multi-domain] Cd Length: 278 Bit Score: 42.78 E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1192 EEEARDLKKKLGQLRSqlqEARDQHREAVHHAE-KMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSR---------- 1260
Cdd:pfam14992 30 EEEIQSLEREITLTRS---LAEDEEREELNFTImEKEDALQELELETAKLEKKNEILVKSVMELQRKLSRksdkntgleq 106
|
90
....*....|....*....
gi 568941652 1261 ---VNLSEEDKEKLQKLTE 1276
Cdd:pfam14992 107 etlKQMLEELKVKLQQSEE 125
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1067-1301 |
1.20e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.28 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1067 KQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQfqdvLTRFQAESQRHSLRLEDRNQELVSECSHLRERL 1146
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE----LEALQAEIDKLQAEIAEAEAEIEERREELGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1147 -CQYENEKAEREVVVRQLQQELADTLKKQSMseasLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAvhhAEK 1225
Cdd:COG3883 93 rALYRSGGSVSYLDVLLGSESFSDFLDRLSA----LSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL---KAE 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568941652 1226 MEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvnLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAE 1301
Cdd:COG3883 166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAE--LEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
|
|
| TRPV1-4 |
cd22193 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are ... |
83-207 |
1.29e-03 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are thermo-sensing channels that function directly in temperature-sensing and nociception; they share substantial structural and functional properties. Transient Receptor Potential (TRP) ion channels activated by temperature (thermo TRPs) are important molecular players in acute, inflammatory, and chronic pain states. So far, 11 TRP channels in mammalian cells have been identified as thermosensitive TRP (thermo-TRP) channels. TRPV1-4 channels are activated by different heat temperatures, for example, TRPV1 and TRPV2 are activated by high temperatures (>43C and >55C, respectively). TRPV1-4 belong to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.
Pssm-ID: 411977 [Multi-domain] Cd Length: 607 Bit Score: 43.25 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 83 TALHLACAYGHPEVVTLLVE---RKCEIDARDSESSTALIKAVQCQEeecaailldhgadpnvmDSSGNTALHYAVYSEN 159
Cdd:cd22193 125 LPLSLAACTNQPDIVQYLLEnehQPADIEAQDSRGNTVLHALVTVAD-----------------NTKENTKFVTRMYDMI 187
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 568941652 160 TSMAAKLLAHNANIEAKNKDDLTPMLLAVKENK----QHIVEFLVKKKASIH 207
Cdd:cd22193 188 LIRGAKLCPTVELEEIRNNDGLTPLQLAAKMGKieilKYILQREIKEPELRH 239
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
745-1237 |
1.43e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.22 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 745 DQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRtlemELKTVKSHLNQVLEERNETQRQLSREQNARmlqdgilashlcK 824
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELK----EAEEKEEEYAELQEELEELEEELEELEAEL------------E 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 825 QKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKsHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEE 904
Cdd:COG4717 113 ELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQLSLATE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 905 tftKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASAlHDHAEIQTAKRDLEIAFQRA--RDEWFR 982
Cdd:COG4717 192 ---EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA-ALEERLKEARLLLLIAAALLalLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 983 VKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVS 1062
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1063 KFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDK--TIVNIQDQFQDVLTRF-QAESQRHSLRLEDRNQELVSEC 1139
Cdd:COG4717 348 ELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElrAALEQAEEYQELKEELeELEEQLEELLGELEELLEALDE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1140 SHLRERLCQYENEKAEREVVVRQLQQELADTlkKQSMSEASlevssryrsnLEEEARDLKKKLGQLRSQLQEARDQHREA 1219
Cdd:COG4717 428 EELEEELEELEEELEELEEELEELREELAEL--EAELEQLE----------EDGELAELLQELEELKAELRELAEEWAAL 495
|
490
....*....|....*...
gi 568941652 1220 VHHAEKMEDHLQKLELEK 1237
Cdd:COG4717 496 KLALELLEEAREEYREER 513
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1126-1315 |
1.63e-03 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 42.74 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1126 LRLED-RNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELadtlkKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQ 1204
Cdd:pfam15742 95 LELEVlKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKL-----EHAHKVCLTDTCILEKKQLEERIKEASENEAK 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1205 LRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRV----NLSEEDKEKLQKLTELKES 1280
Cdd:pfam15742 170 LKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSQQQLRIQQQEAQLKQLenekRKSDEHLKSNQELSEKLSS 249
|
170 180 190
....*....|....*....|....*....|....*
gi 568941652 1281 LectvdqeQKRSSALEKELAEFKEVLKMTKKELNE 1315
Cdd:pfam15742 250 L-------QQEKEALQEELQQVLKQLDVHVRKYNE 277
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1068-1318 |
1.70e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.19 E-value: 1.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1068 QESIEERLAQ---LQSENTLLRQQLDDAANKAESKDKtIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELvsecSHLRE 1144
Cdd:pfam17380 281 QKAVSERQQQekfEKMEQERLRQEKEEKAREVERRRK-LEEAEKARQAEMDRQAAIYAEQERMAMEREREL----ERIRQ 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1145 RLCQYENEKAEREVV------VRQLQQELADTLKKQSMSEASLEVSSRYRsnLEEEARdlKKKLGQLRSQLQEARDQHRE 1218
Cdd:pfam17380 356 EERKRELERIRQEEIameisrMRELERLQMERQQKNERVRQELEAARKVK--ILEEER--QRKIQQQKVEMEQIRAEQEE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1219 AvhhaekMEDHLQKLELEKSKfeiTIKKQSEEIDQLQENLSRVNLSEEDKEKlQKLTELKESLECTVDQEQKRsSALEKE 1298
Cdd:pfam17380 432 A------RQREVRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEERKR-KKLELEKEKRDRKRAEEQRR-KILEKE 500
|
250 260
....*....|....*....|....*..
gi 568941652 1299 LAEFKEVL-------KMTKKELNEYEN 1318
Cdd:pfam17380 501 LEERKQAMieeerkrKLLEKEMEERQK 527
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1190-1468 |
2.17e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 42.64 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1190 NLEEEARDLKKKLGQLRSQLQEARDQhREAVHHAEKMEDHLQKLELE------KSKFEITIKKQSEEIDQLQ-------- 1255
Cdd:COG5185 279 RLNENANNLIKQFENTKEKIAEYTKS-IDIKKATESLEEQLAAAEAEqeleesKRETETGIQNLTAEIEQGQesltenle 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1256 ---ENLSRVNLSEEDKEKLQKLTELKESLECTVDQ-EQKRSSALEKElaefKEVLKMTKKELNEYENRELNLRQDIKNNH 1331
Cdd:COG5185 358 aikEEIENIVGEVELSKSSEELDSFKDTIESTKESlDEIPQNQRGYA----QEILATLEDTLKAADRQIEELQRQIEQAT 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1332 LEMDIPVSTLIKKIDDLTAKLETASSKclhlgKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEH 1411
Cdd:COG5185 434 SSNEEVSKLLNELISELNKVMREADEE-----SQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKL 508
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 568941652 1412 SQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELR 1468
Cdd:COG5185 509 ERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANL 565
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
995-1326 |
2.37e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 42.52 E-value: 2.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 995 RDNNEVLSQQLSKTERKLNSLEiefhhtkDELRekTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEER 1074
Cdd:PRK04778 71 QKWDEIVTNSLPDIEEQLFEAE-------ELND--KFRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREE 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1075 LAQL-----QSENTLL--RQQLDDAANKAESKdktIVNIQDQFQDVLTRFQA----ESQRHSLRLEDRNQELvsecSHLR 1143
Cdd:PRK04778 142 VEQLkdlyrELRKSLLanRFSFGPALDELEKQ---LENLEEEFSQFVELTESgdyvEAREILDQLEEELAAL----EQIM 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1144 ERLCQyenekaerevVVRQLQQELADTLKKQSMSEASLEVSSRY--RSNLEEEARDLKKKLGQLRSQLQEAR-DQHREAV 1220
Cdd:PRK04778 215 EEIPE----------LLKELQTELPDQLQELKAGYRELVEEGYHldHLDIEKEIQDLKEQIDENLALLEELDlDEAEEKN 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1221 HHAEKMEDHL-----------QKLELEKSKFEITIKKQSEEIDQLQENLSRVN----LSEEDKEKLQKLTELKESLECTV 1285
Cdd:PRK04778 285 EEIQERIDQLydilerevkarKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKqsytLNESELESVRQLEKQLESLEKQY 364
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 568941652 1286 DQEQKRS-------SALEKELAEFKEVLKMTKKELNEYENRELNLRQD 1326
Cdd:PRK04778 365 DEITERIaeqeiaySELQEELEEILKQLEEIEKEQEKLSEMLQGLRKD 412
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
741-1352 |
2.44e-03 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 42.75 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 741 RRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLE--ERNETQRQLSREQNARMLQDGIL 818
Cdd:COG5244 65 RPDDDSLLNGNAAYEKIKGGLVCESKGMDKDGEIKQENHEDRIHFEESKIRRLEEtiEALKSTEKEEIVELRRENEELDK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 819 ASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLedikiANEKNDNLQRM 898
Cdd:COG5244 145 INLSLRERISSEEPELNKDGSKLSYDELKEFVEESRVQVYDMVELVSDISETLNRNGSIQRSSV-----RECERSNIHDV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 899 VKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSrlasalhdhaeiqtakrdLEIAFQRARD 978
Cdd:COG5244 220 LFLVNGILDGVIDELNGELERLRRQLVSLMSSHGIEVEENSRLKATLEKFQS------------------LELKVNTLQE 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 979 EWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNS-----LE-IEFHHTKDELREKTLALK------HAQRDLSQTQCQ 1046
Cdd:COG5244 282 ELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEVIESenfgkLEnIEIHIILKVLSSISYALHiytiknTPDHLETTLQCF 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1047 MKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENT------LLRQQLDDAANKAESKDKTIVNIQD------------ 1108
Cdd:COG5244 362 VNIAPISMWLSEFLQRKFSSKQETAFSICQFLEDNKDvtlilkILHPILETTVPKLLAFLRTNSNFNDndtlcligslye 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1109 -QFQDVLTRFQAESQRHSlRLEDRNQELVSECSHLR-------ERLCQYeNEKAEREVVVRQLQQELADTLKKQSMSEAS 1180
Cdd:COG5244 442 iARIDKLIGKEEISKQDN-RLFLYPSCDITLSSILTilfsdklEVFFQG-IESLLENITIFPEQPSQQTSDSENIKENSL 519
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1181 LevssryRSNLEEEARDLKKKLGQLRSQLQEardqhreavhhaEKMEDHLQKLELEKSKFEITIKKQSEEIdqlqeNLSR 1260
Cdd:COG5244 520 L------SDRLNEENIRLKEVLVQKENMLTE------------ETKIKIIIGRDLERKTLEENIKTLKVEL-----NNKN 576
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1261 VNLSEEDKEKLQKLTELKESLECTVDQ--EQKRSSALEKELAEFKEVLKMTKKELNEyENRELNLRQDIKNNHLEMDIPV 1338
Cdd:COG5244 577 NKLKEENFNLVNRLKNMELKLYQIKDNntLNKIYLDLVSEIMELRETIRRQIKEQKR-VSIDFSWLDELKQPFKEHIIEM 655
|
650
....*....|....
gi 568941652 1339 STLIKKIDDLTAKL 1352
Cdd:COG5244 656 FNFVSTSRILDLKL 669
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1003-1167 |
2.44e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.63 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1003 QQLSKTERKLNSLEIEFHHtKDELREKTLALKHAQRDLSQTQCQMKEV----EHM-FQDEQGKVSKFMGKQESIEERLAQ 1077
Cdd:COG3096 917 KALAQLEPLVAVLQSDPEQ-FEQLQADYLQAKEQQRRLKQQIFALSEVvqrrPHFsYEDAVGLLGENSDLNEKLRARLEQ 995
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1078 LQSENTLLRQQLDDAANKAESKDKTIVNIQDQF---QDVLTRFQAESQRHSLRL--------EDRNQELVSECSHLRERL 1146
Cdd:COG3096 996 AEEARREAREQLRQAQAQYSQYNQVLASLKSSRdakQQTLQELEQELEELGVQAdaeaeeraRIRRDELHEELSQNRSRR 1075
|
170 180
....*....|....*....|.
gi 568941652 1147 CQYENEKAEREVVVRQLQQEL 1167
Cdd:COG3096 1076 SQLEKQLTRCEAEMDSLQKRL 1096
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
147-175 |
3.65e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.41 E-value: 3.65e-03
10 20
....*....|....*....|....*....
gi 568941652 147 GNTALHYAVYSENTSMAAKLLAHNANIEA 175
Cdd:smart00248 2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
653-1108 |
4.02e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.81 E-value: 4.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 653 HLRLECKDTASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMENKYKglqkEMSETEEVKSRLE-HEKVGWEQELCRLR 731
Cdd:PRK01156 236 NLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHM----KIINDPVYKNRNYiNDYFKYKNDIENKK 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 732 FALKQEEEKRRSADQLSEKTS--EQLRRKGEQCQSEVEARQQLEASLRTLEME----LKTVKShLNQVLEERNETQRQLS 805
Cdd:PRK01156 312 QILSNIDAEINKYHAIIKKLSvlQKDYNDYIKKKSRYDDLNNQILELEGYEMDynsyLKSIES-LKKKIEEYSKNIERMS 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 806 REQNARMLQDGILASHLCKQK-EIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLE--------------MDTI 870
Cdd:PRK01156 391 AFISEILKIQEIDPDAIKKELnEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQsvcpvcgttlgeekSNHI 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 871 KSHNQEKEKRYLEDI--------KIANEKNDNLQRMVKLNEETFTKTIFQYTgQLNSLKAENTMLSSKLDNEKQNKERLE 942
Cdd:PRK01156 471 INHYNEKKSRLEEKIreieievkDIDEKIVDLKKRKEYLESEEINKSINEYN-KIESARADLEDIKIKINELKDKHDKYE 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 943 TDVESFRSRlasalhdhaeiqtakrDLEIAFQRaRDEWFRVKDKM-NFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHH 1021
Cdd:PRK01156 550 EIKNRYKSL----------------KLEDLDSK-RTSWLNALAVIsLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPD 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1022 TKD-------ELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQ---QLDD 1091
Cdd:PRK01156 613 DKSyidksirEIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKsrkALDD 692
|
490
....*....|....*...
gi 568941652 1092 A-ANKAESKDKTIVNIQD 1108
Cdd:PRK01156 693 AkANRARLESTIEILRTR 710
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
678-1287 |
4.04e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 42.35 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 678 IELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEK---VGWEQELCRLrFALKQEEEKRRSADQLSE----- 749
Cdd:TIGR01612 1171 IEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKginLSYGKNLGKL-FLEKIDEEKKKSEHMIKAmeayi 1249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 750 KTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHlnQVLEERNETQRQLSREQNARMLQDgilashLCKQKEIE 829
Cdd:TIGR01612 1250 EDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDH--HIISKKHDENISDIREKSLKIIED------FSEESDIN 1321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 830 MTQKKMTSEVSVSHEKEKDLlhkNQRLqDEVAVLR--LEMDTIKShNQEKEKRYLEDIKianEKNDNLQRMVKlNEETFT 907
Cdd:TIGR01612 1322 DIKKELQKNLLDAQKHNSDI---NLYL-NEIANIYniLKLNKIKK-IIDEVKEYTKEIE---ENNKNIKDELD-KSEKLI 1392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 908 KTIfQYTGQLNSLKA--ENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAE----IQTAKRDLEIAFQRARDEWF 981
Cdd:TIGR01612 1393 KKI-KDDINLEECKSkiESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADEnnenVLLLFKNIEMADNKSQHILK 1471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 982 RVKDK----MNFDMSNLRDNNEvlSQQLSKTERKLNSLEIE-----FHHTKDELRE-----KTLALKHaqrDLSQTQcqm 1047
Cdd:TIGR01612 1472 IKKDNatndHDFNINELKEHID--KSKGCKDEADKNAKAIEknkelFEQYKKDVTEllnkySALAIKN---KFAKTK--- 1543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1048 KEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRqqlDDAANKAESkDKTIVNIQDQFQDVLTRFqaesqrhsLR 1127
Cdd:TIGR01612 1544 KDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIE---DDAAKNDKS-NKAAIDIQLSLENFENKF--------LK 1611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1128 LEDRNQELVSecshlrerlCQYENEKAEREVvvrqlqqeladtlkkqsmSEASLEVSSRYRSNLEEEARDLKKKLGQLRS 1207
Cdd:TIGR01612 1612 ISDIKKKIND---------CLKETESIEKKI------------------SSFSIDSQDTELKENGDNLNSLQEFLESLKD 1664
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1208 QLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENlsrvnlseedkeklqKLTELKESLECTVDQ 1287
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKE---------------EIESIKELIEPTIEN 1729
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1173-1304 |
4.05e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.74 E-value: 4.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1173 KQSMSEASLEVSsRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELE-KSKFEITIKKQSEEI 1251
Cdd:PRK00409 508 KKLIGEDKEKLN-ELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEaEKEAQQAIKEAKKEA 586
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 568941652 1252 DQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKE 1304
Cdd:PRK00409 587 DEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELKV 639
|
|
| PHA02736 |
PHA02736 |
Viral ankyrin protein; Provisional |
132-204 |
4.38e-03 |
|
Viral ankyrin protein; Provisional
Pssm-ID: 165103 [Multi-domain] Cd Length: 154 Bit Score: 39.47 E-value: 4.38e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568941652 132 ILLDHGADPNVMDS-SGNTALHYAVYSENTSMAAKLLAH-NANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKA 204
Cdd:PHA02736 76 LLMEWGADINGKERvFGNTPLHIAVYTQNYELATWLCNQpGVNMEILNYAFKTPYYVACERHDAKMMNILRAKGA 150
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1193-1434 |
4.72e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 4.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1193 EEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKlq 1272
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA-- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1273 KLTELKESLECTVDQEQKRSSALEKEL----AEFKEVLKMTK--KELNEYENRELN-LRQDIKNnhlemdipVSTLIKKI 1345
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQylKYLAPARREQAEeLRADLAE--------LAALRAEL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1346 DDLTAKLETAsskclhLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERA 1425
Cdd:COG4942 170 EAERAELEAL------LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
....*....
gi 568941652 1426 RQDLVEKLK 1434
Cdd:COG4942 244 PAAGFAALK 252
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1156-1529 |
5.05e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.81 E-value: 5.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1156 REVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQ--LRSQLQEARDQHREAVHHAEKMEDHLQKL 1233
Cdd:PLN02939 40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQksTSSDDDHNRASMQRDEAIAAIDNEQQTNS 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1234 ELEKSKFEITIKKQSEEIDQLQENLSRVNLSE----EDKEKLqkLTElKESLectvdqeQKRSSALEKELAEFKEVLKMT 1309
Cdd:PLN02939 120 KDGEQLSDFQLEDLVGMIQNAEKNILLLNQARlqalEDLEKI--LTE-KEAL-------QGKINILEMRLSETDARIKLA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1310 KKELNEYENRE---LNLRQDIKNNHLEMDIPVSTLIKKIDDLtaKLETASSK--CLHLGKKNQLLQQELLLMRTIQKKCG 1384
Cdd:PLN02939 190 AQEKIHVEILEeqlEKLRNELLIRGATEGLCVHSLSKELDVL--KEENMLLKddIQFLKAELIEVAETEERVFKLEKERS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1385 KLEKNKKQLEQEVVNLRSHMEKnmVEHSQAQQYAREVEERarQDLVEKLK----QVNLFLQAQAASQESLEQLRENSNAS 1460
Cdd:PLN02939 268 LLDASLRELESKFIVAQEDVSK--LSPLQYDCWWEKVENL--QDLLDRATnqveKAALVLDQNQDLRDKVDKLEASLKEA 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941652 1461 VRSQMELRIKDLESQlyRMKA-QEDFDKI--ELEKYKQLYQEefrarksLSSKLNKTSEKLEEASSKLLLEE 1529
Cdd:PLN02939 344 NVSKFSSYKVELLQQ--KLKLlEERLQASdhEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSLEH 406
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
1068-1249 |
6.87e-03 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 40.83 E-value: 6.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1068 QESIEERLAQLQSENTLLRQQLDDAANKAESkdktIVNIQDQFQDVLTRFQ-AESQrhslrLEDRNQELVSECSHLR--- 1143
Cdd:COG0497 225 REALQEALEALSGGEGGALDLLGQALRALER----LAEYDPSLAELAERLEsALIE-----LEEAASELRRYLDSLEfdp 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1144 ERLcqyeNEKAEREVVVRQLQQ-------ELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARdqh 1216
Cdd:COG0497 296 ERL----EEVEERLALLRRLARkygvtveELLAYAEELRAELAELENSDERLEELEAELAEAEAELLEAAEKLSAAR--- 368
|
170 180 190
....*....|....*....|....*....|....
gi 568941652 1217 REAVHH-AEKMEDHLQKLELEKSKFEITIKKQSE 1249
Cdd:COG0497 369 KKAAKKlEKAVTAELADLGMPNARFEVEVTPLEE 402
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
133-213 |
7.04e-03 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 40.81 E-value: 7.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 133 LLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHI--VEFLVKKKASI-HAV 209
Cdd:PHA02946 58 LLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEVIerINLLVQYGAKInNSV 137
|
....
gi 568941652 210 DQLG 213
Cdd:PHA02946 138 DEEG 141
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1072-1399 |
9.24e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.71 E-value: 9.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1072 EERLAQlqsentlLRQQLDDAANKAESKDKTIVNIQDQFQDvLTRFQAESQRHSLRlEDRNQELVSecshLRERLCQYEN 1151
Cdd:PRK04863 785 EKRIEQ-------LRAEREELAERYATLSFDVQKLQRLHQA-FSRFIGSHLAVAFE-ADPEAELRQ----LNRRRVELER 851
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1152 EKAEREVVVRQLQQELaDTLKKQSMSEASLEVSSryrSNLEEEarDLKKKLGQLRSQLQEARDQHREAVHH---AEKMED 1228
Cdd:PRK04863 852 ALADHESQEQQQRSQL-EQAKEGLSALNRLLPRL---NLLADE--TLADRVEEIREQLDEAEEAKRFVQQHgnaLAQLEP 925
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1229 HLQKLELEKSKFEiTIKKQSEEIDQLQENLS------------RVNLSEEDKEK-LQKLTELKESLectvdqeQKRSSAL 1295
Cdd:PRK04863 926 IVSVLQSDPEQFE-QLKQDYQQAQQTQRDAKqqafaltevvqrRAHFSYEDAAEmLAKNSDLNEKL-------RQRLEQA 997
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1296 EKELAEFKEVLKMTKKELNEYENRELNL----------RQDIKNNHLEMDIPVST-----LIKKIDDLTAKLETASSKCL 1360
Cdd:PRK04863 998 EQERTRAREQLRQAQAQLAQYNQVLASLkssydakrqmLQELKQELQDLGVPADSgaeerARARRDELHARLSANRSRRN 1077
|
330 340 350
....*....|....*....|....*....|....*....
gi 568941652 1361 HLGKKnqlLQQELLLMRTIQKKCGKLEKNKKQLEQEVVN 1399
Cdd:PRK04863 1078 QLEKQ---LTFCEAEMDNLTKKLRKLERDYHEMREQVVN 1113
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
651-911 |
9.50e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 40.73 E-value: 9.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 651 IEHLRLECKDTASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKvgwEQELCRL 730
Cdd:pfam02463 755 SRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI---EQEEKIK 831
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 731 RFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSR---E 807
Cdd:pfam02463 832 EEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQklnL 911
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 808 QNARMLQDGILASHLCKQKEIEMTQKKMTS-----EVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYL 882
Cdd:pfam02463 912 LEEKENEIEERIKEEAEILLKYEEEPEELLleeadEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYN 991
|
250 260 270
....*....|....*....|....*....|...
gi 568941652 883 ED----IKIANEKNDNLQRMVKLNEETFTKTIF 911
Cdd:pfam02463 992 KDelekERLEEEKKKLIRAIIEETCQRLKEFLE 1024
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
848-1353 |
9.52e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 40.66 E-value: 9.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 848 DLLHKNQRLQDEVAVLRLEMD---TIKSHNQEKEKRYLEDIKIANEKNDN----LQRMVKLNEET--FTKTIFQYTGQLN 918
Cdd:PRK01156 187 YLEEKLKSSNLELENIKKQIAddeKSHSITLKEIERLSIEYNNAMDDYNNlksaLNELSSLEDMKnrYESEIKTAESDLS 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 919 SLKAENTMLSS------KLDNEKQNKER--------LETDVESFRSRLASALHDHAEIQTAKRDLEIaFQRARDEWF--- 981
Cdd:PRK01156 267 MELEKNNYYKEleerhmKIINDPVYKNRnyindyfkYKNDIENKKQILSNIDAEINKYHAIIKKLSV-LQKDYNDYIkkk 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 982 RVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKV 1061
Cdd:PRK01156 346 SRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKV 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1062 SKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVsecsH 1141
Cdd:PRK01156 426 SSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIV----D 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1142 LRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASL--------EVSSRYRS----NLEEEARDLKKKLGQLRS-Q 1208
Cdd:PRK01156 502 LKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELkdkhdkyeEIKNRYKSlkleDLDSKRTSWLNALAVISLiD 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1209 LQEARDQHREAVHHAEKMEDHLQKLELE----KSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECT 1284
Cdd:PRK01156 582 IETNRSRSNEIKKQLNDLESRLQEIEIGfpddKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAE 661
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941652 1285 VDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEmdipVSTLIKKIDDLTAKLE 1353
Cdd:PRK01156 662 IDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTR----INELSDRINDINETLE 726
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
1182-1414 |
9.99e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 40.68 E-value: 9.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1182 EVSSRYRSNLEEEARDLKKKLGQLRSQLQEAR-DQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSR 1260
Cdd:PRK05771 39 ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNpLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKE 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1261 VnlsEEDKEKLQKLTELKESLEC------------TVDQEQKRSSALEKELAEFKE---------VLKMTKKELNEYENR 1319
Cdd:PRK05771 119 L---EQEIERLEPWGNFDLDLSLllgfkyvsvfvgTVPEDKLEELKLESDVENVEYistdkgyvyVVVVVLKELSDEVEE 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941652 1320 ELNlRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHlgkknqllqqelllmrtiqkkcgKLEKNKKQLEQEVVN 1399
Cdd:PRK05771 196 ELK-KLGFERLELEEEGTPSELIREIKEELEEIEKERESLLE-----------------------ELKELAKKYLEELLA 251
|
250
....*....|....*
gi 568941652 1400 LRSHMEkNMVEHSQA 1414
Cdd:PRK05771 252 LYEYLE-IELERAEA 265
|
|
| |
