|
Name |
Accession |
Description |
Interval |
E-value |
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
169-1600 |
2.63e-118 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 414.41 E-value: 2.63e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 169 KYWERGFVALQTAINAGIIEvttnhSVMEELMSIdGINMKTLPFiPRDLSDYEIFIL---FCLLYFSSFIYFAS----SN 241
Cdd:TIGR01257 602 RYIWGGFAYLQDMVEQGITR-----SQMQAEPPV-GIYLQQMPY-PCFVDDSFMIILnrcFPIFMVLAWIYSVSmtvkSI 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 242 VTKERKQCKEVMKVMGLQDSAFWLSWGLIYVGFIFIISIFIAIIITSTQIIMMTGFLVIFTLFFLYGLSLIAVTFLMAVL 321
Cdd:TIGR01257 675 VLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGRILHYSDPFILFLFLLAFSTATIMQCFLLSTF 754
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 322 LQKAVLTNLI--VLFFTLFWGCVGFTVLHKELPPSLEWVLSIFSPFAFTSGMAKVI-FQDYNL----NGVVFPDPSGESY 394
Cdd:TIGR01257 755 FSKASLAAACsgVIYFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFGFGTEYLVrFEEQGLglqwSNIGNSPLEGDEF 834
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 395 VMIAVFFILAFDSLLYLVLALYFDKILL--YGAehrSAPLFFLNPTSCF-----------RKTANRNKVIERDLDPELP- 460
Cdd:TIGR01257 835 SFLLSMKMMLLDAALYGLLAWYLDQVFPgdYGT---PLPWYFLLQESYWlggegcstreeRALEKTEPLTEEMEDPEHPe 911
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 461 --SDEYFEPVDPEYQgkEAIRIRNIKKEYKgKSGKvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSV 538
Cdd:TIGR01257 912 giNDSFFERELPGLV--PGVCVKNLVKIFE-PSGR-PAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTV 987
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 539 TVYNKNLSdmQDLKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEG 618
Cdd:TIGR01257 988 LVGGKDIE--TNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGG 1065
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 619 QKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSV 698
Cdd:TIGR01257 1066 MQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPL 1145
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 699 FLKRKWGLGYHLSLFM------------DETC--------------------------DSERLTSFINHHIPYAKLKAKT 740
Cdd:TIGR01257 1146 FLKNCFGTGFYLTLVRkmkniqsqrggcEGTCsctskgfstrcparvdeitpeqvldgDVNELMDLVYHHVPEAKLVECI 1225
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 741 KEKLVYILPLE--RTSEFPEFFSDLDK-YSGQGLMSYEVSMSTLNDVFLNLEGEPSTKQDF-----EKRE---------- 802
Cdd:TIGR01257 1226 GQELIFLLPNKnfKQRAYASLFRELEEtLADLGLSSFGISDTPLEEIFLKVTEDADSGSLFaggaqQKREnanlrhpcsg 1305
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 803 -------TATDSESLNDMEVAYPSLSQVQ----------ETVSTMSLWRMQVCAIARLRilKLKRERKAFLIILLLLGIA 865
Cdd:TIGR01257 1306 ptekagqTPQASHTCSPGQPAAHPEGQPPpepedpgvplNTGARLILQHVQALLVKRFQ--HTIRSHKDFLAQIVLPATF 1383
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 866 LLPLVI-----------------------EYVANALLEVKNNW-EFKTDLYFLSPG------------------------ 897
Cdd:TIGR01257 1384 VFLALMlsiiippfgeypaltlhpwmygqQYTFFSMDEPNSEHlEVLADVLLNKPGfgnrclkeewlpeypcgnstpwkt 1463
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 898 -------------------------------------QLPQGL----------RTSLLVINNTESNIEDFL--------- 921
Cdd:TIGR01257 1464 psvspnithlfqkqkwtaahpspscrcstrekltmlpECPEGAgglpppqrtqRSTEILQDLTDRNISDFLvktypalir 1543
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 922 QSLKHQNIV-------------LEVDDFENRNATNSLSYNGAII-VSG----RQKDYRFSAVC-------------NTKR 970
Cdd:TIGR01257 1544 SSLKSKFWVneqryggisiggkLPAIPITGEALVGFLSDLGQMMnVSGgpvtREASKEMPDFLkhletednikvwfNNKG 1623
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 971 LHCFPILMNVISNGILHMLNH-------------TQYIRIKEDIFSPFIVLVwTGIQetCLFILCVICSLS---PHIAMS 1034
Cdd:TIGR01257 1624 WHALVSFLNVAHNAILRASLPkdrdpeeygitviSQPLNLTKEQLSEITVLT-TSVD--AVVAICVIFAMSfvpASFVLY 1700
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1035 SVSDYKKKADSQLWISGLYPSAYWCGQAVVDISLF--SGMLLTSYFTSYTSKLLNidmTSEIVFSVIVLALGCAASLVFL 1112
Cdd:TIGR01257 1701 LIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYavSAGLVVGIFIGFQKKAYT---SPENLPALVALLMLYGWAVIPM 1777
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1113 TYVISFVFGKRKKNSTLWSICFLLV----IAITF--EKVANG----PFNeALVISATMLVPSFALN-GLL-VVLEMRAYQ 1180
Cdd:TIGR01257 1778 MYPASFLFDVPSTAYVALSCANLFIginsSAITFvlELFENNrtllRFN-AMLRKLLIVFPHFCLGrGLIdLALSQAVTD 1856
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1181 YYIEF-EEIKHGLSAVDLLLCLIPYIHTLLFIFVLRCLELKYGKNVVRrdpifriapqsLKAQPNPEEPIDEDENVQAER 1259
Cdd:TIGR01257 1857 VYAQFgEEHSANPFQWDLIGKNLVAMAVEGVVYFLLTLLIQHHFFLSR-----------WIAEPAKEPIFDEDDDVAEER 1925
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1260 LRTsdaLSTPNldEKPVIIASCLHKEYAGqkkhccsrrTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKP 1339
Cdd:TIGR01257 1926 QRI---ISGGN--KTDILRLNELTKVYSG---------TSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTV 1991
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1340 TAGQVELKRlSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQN 1419
Cdd:TIGR01257 1992 TSGDATVAG-KSILTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGT 2070
|
1530 1540 1550 1560 1570 1580 1590 1600
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1420 LVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDnEKGVLLSTHDLAEAEALCDRAAIMVSGRLR 1499
Cdd:TIGR01257 2071 YSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQ 2149
|
1610 1620 1630 1640 1650 1660 1670 1680
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1500 CIGPIQHLKRKFGQDYVLELRVKDVSQEPL-----VHREILKLFPQAARQDRCFSLLTYKLPVTDvhpLSQAFHKLEAVK 1574
Cdd:TIGR01257 2150 CLGTIQHLKSKFGDGYIVTMKIKSPKDDLLpdlnpVEQFFQGNFPGSVQRERHYNMLQFQVSSSS---LARIFQLLISHK 2226
|
1690 1700
....*....|....*....|....*.
gi 568976233 1575 HGFDLEDYSLSQCTLDRVILELSKEQ 1600
Cdd:TIGR01257 2227 DSLLIEEYSVTQTTLDQVFVNFAKQQ 2252
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
478-701 |
1.28e-75 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 250.11 E-value: 1.28e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlSDMQDLKEIRKA 557
Cdd:cd03263 1 LQIRNLTKTYKKGT--KPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGY--SIRTDRKAARQS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03263 77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVFLK 701
Cdd:cd03263 157 LDEPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
1282-1508 |
3.84e-74 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 245.88 E-value: 3.84e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQKKHccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSsAVGHQGDSRA 1361
Cdd:cd03263 6 LTKTYKKGTKP---------AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYS-IRTDRKAARQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1362 EFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVL 1441
Cdd:cd03263 76 SLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAVVKdnEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLK 1508
Cdd:cd03263 156 LLDEPTSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
478-696 |
8.32e-66 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 222.63 E-value: 8.32e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmqDLKEIRKA 557
Cdd:COG1131 1 IEVRGLTKRY----GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVAR--DPAEVRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:COG1131 75 IGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLI 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:COG1131 155 LDEPTSGLDPEARRELWELLRElAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGT 214
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
1282-1519 |
8.57e-66 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 222.63 E-value: 8.57e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL-----KRLSSAVghq 1356
Cdd:COG1131 6 LTKRYGDKT-----------ALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVlgedvARDPAEV--- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 gdsRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILG 1436
Cdd:COG1131 72 ---RRRIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLH 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1437 NSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYV 1516
Cdd:COG1131 149 DPELLILDEPTSGLDPEARRELWELLRELAAEG-KTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARLLEDVF 227
|
...
gi 568976233 1517 LEL 1519
Cdd:COG1131 228 LEL 230
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
478-696 |
2.89e-55 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 192.77 E-value: 2.89e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdmQDLKEIRKA 557
Cdd:COG4555 2 IEVENLSKKY----GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVR--KEPREARRQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:COG4555 76 IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:COG4555 156 LDEPTNGLDVMARRLLREILRAlKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGS 215
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1300-1527 |
1.32e-52 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 185.06 E-value: 1.32e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL-----KRLSSAVghqgdsRAEFGYCPQENGLWP 1374
Cdd:COG4555 14 VPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIdgedvRKEPREA------RRQIGVLPDERGLYD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSG 1454
Cdd:COG4555 88 RLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1455 KHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLELRVKDVSQE 1527
Cdd:COG4555 168 RRLLREILRA-LKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENLEDAFVALIGSE 239
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
478-689 |
3.64e-51 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 178.36 E-value: 3.64e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmqDLKEIRKA 557
Cdd:cd03230 1 IEVRNLSKRY----GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKK--EPEEVKRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLtlfakikgilpqdveqevqqilseldmqnirddlaeHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03230 75 IGYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLI 118
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03230 119 LDEPTSGLDPESRREFWELLRELKKEGKtILLSSHILEEAERLCDRVAILNNG 171
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
1299-1498 |
9.60e-50 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 174.12 E-value: 9.60e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLsSAVGHQGDSRAEFGYCPQENGLWPNLTV 1378
Cdd:cd03230 12 KKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGK-DIKKEPEEVKRRIGYLPEEPSLYENLTV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELyaavkglrkedavvaiSRlvnalklhdqlnvqvqnlvaGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQV 1458
Cdd:cd03230 91 RENLKL----------------SG--------------------GMKQRLALAQALLHDPELLILDEPTSGLDPESRREF 134
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 568976233 1459 WQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:cd03230 135 WELLRELKKEG-KTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1302-1520 |
4.87e-49 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 176.84 E-value: 4.87e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVghqgdsRAEFGYCPQENGLWPNLTVK 1379
Cdd:COG4152 16 AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWdgEPLDPED------RRRIGYLPEERGLYPKMKVG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVW 1459
Cdd:COG4152 90 EQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLK 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1460 QAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFG-QDYVLELR 1520
Cdd:COG4152 170 DVIRE-LAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGrNTLRLEAD 230
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
1277-1508 |
1.58e-47 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 169.86 E-value: 1.58e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1277 IIASCLHKEYAGqkkhccsrrtrNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSsAVGHQ 1356
Cdd:cd03265 1 IEVENLVKKYGD-----------FEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHD-VVREP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 GDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILG 1436
Cdd:cd03265 69 REVRRRIGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVH 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1437 NSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLK 1508
Cdd:cd03265 149 RPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
1299-1502 |
7.99e-47 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 167.46 E-value: 7.99e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQgdsraeFGYCPQENGLWPNL 1376
Cdd:cd03269 12 RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFdgKPLDIAARNR------IGYLPEERGLYPKM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKH 1456
Cdd:cd03269 86 KVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVE 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568976233 1457 QVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03269 166 LLKDVIRE-LARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
492-790 |
4.77e-46 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 168.34 E-value: 4.77e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLsdMQDLKEIRKAIGVCPQHNVQFDAL 571
Cdd:TIGR01188 4 GDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDV--VREPRKVRRSIGIVPQYASVDEDL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 572 TVKENLTLFAKIKGiLPQDV-EQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSR 650
Cdd:TIGR01188 82 TGRENLEMMGRLYG-LPKDEaEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 651 QRIWGFL-KERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVFLKRKWGlgyhlslfmDETCDSERlTSFINH 729
Cdd:TIGR01188 161 RAIWDYIrALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLG---------KDTLESRP-RDIQSL 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 730 HIPYAKLKAKTKEKLVYILPLERTSE------------FPEFFSDLDKySGQGLMSYEVSMSTLNDVFLNLEG 790
Cdd:TIGR01188 231 KVEVSMLIAELGETGLGLLAVTVDSDrikilvpdgdetVPEIVEAAIR-NGIRIRSISTERPSLDDVFLKLTG 302
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
1302-1596 |
1.22e-45 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 167.18 E-value: 1.22e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrLSSAVGHQGDS-RAEFGYCPQENGLWPNLTVKE 1380
Cdd:TIGR01188 8 AVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARV--AGYDVVREPRKvRRSIGIVPQYASVDEDLTGRE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQ 1460
Cdd:TIGR01188 86 NLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIWD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1461 AIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLELRVKDVSQEPLVHREILKLFPQ 1540
Cdd:TIGR01188 166 YIRALKEEG-VTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKDTLESRPRDIQSLKVEVSMLIAELGET 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1541 AARQDRCFSLL-TYKLPVTDvhPLSQAFHKLEAV-KHGFDLEDYSLSQCTLDRVILEL 1596
Cdd:TIGR01188 245 GLGLLAVTVDSdRIKILVPD--GDETVPEIVEAAiRNGIRIRSISTERPSLDDVFLKL 300
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
478-696 |
1.31e-45 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 164.43 E-value: 1.31e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKA 557
Cdd:COG1122 1 IELENLSFSY---PGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITK-KNLRELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQH-NVQFDALTVKENLTlFA-KIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTfgIATV--GDP 633
Cdd:COG1122 77 VGLVFQNpDDQLFAPTVEEDVA-FGpENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVA--IAGVlaMEP 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 634 QILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:COG1122 154 EVLVLDEPTAGLDPRGRRELLELLKRlNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
478-692 |
3.24e-45 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 162.75 E-value: 3.24e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIyESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynKNLSDMQDLKEIRKA 557
Cdd:cd03264 1 LQLENLTKRYGKK----RALDGVSLTL-GPGMYGLLGPNGAGKTTLMRILATLTPPSSGTIRI--DGQDVLKQPQKLRRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03264 74 IGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILI 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALK 692
Cdd:cd03264 154 VDEPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
478-701 |
1.10e-44 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 161.77 E-value: 1.10e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNknLSDMQDLKEIRKA 557
Cdd:cd03265 1 IEVENLVKKY----GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAG--HDVVREPREVRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03265 75 IGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLF 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANGALKCTGSSVFLK 701
Cdd:cd03265 155 LDEPTIGLDPQTRAHVWEYIEKLKEEFgmTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
478-695 |
1.14e-44 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 161.38 E-value: 1.14e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynKNLSDMQDLKEIRKA 557
Cdd:cd03266 2 ITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATV--DGFDVVKEPAEARRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03266 80 LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGALKCTG 695
Cdd:cd03266 160 LDEPTTGLDVMATRALREFIRQlRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
479-689 |
1.31e-44 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 161.10 E-value: 1.31e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 479 RIRNIKKEYKGksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKAI 558
Cdd:cd03225 1 ELKNLSFSYPD--GARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTK-LSLKELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03225 78 GLVFQNpDDQFFGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03225 158 LDEPTAGLDPAGRRELLELLKKlKAEGKTIIIVTHDLDLLLELADRVIVLEDG 210
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1277-1502 |
3.61e-43 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 157.14 E-value: 3.61e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1277 IIASCLHKEYAGQKKHCcsrrtrnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLsSAVGHQ 1356
Cdd:cd03266 2 ITADALTKRFRDVKKTV-------QAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGF-DVVKEP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 GDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILG 1436
Cdd:cd03266 74 AEARRRLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVH 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1437 NSPVLILDEPSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03266 154 DPPVLLLDEPTTGLDVMATRALREFIRQ-LRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1276-1523 |
2.94e-41 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 155.25 E-value: 2.94e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1276 VIIASCLHKEY---------AGQKKHCCSRRTRNM-AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV- 1344
Cdd:COG4586 1 IIEVENLSKTYrvyekepglKGALKGLFRREYREVeAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1345 -----------ELKRLSSAVghqgdsraeFGycpQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQL 1413
Cdd:COG4586 81 vlgyvpfkrrkEFARRIGVV---------FG---QRSQLWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1414 NVQVQNLVAGaTRKLC-FVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAI 1492
Cdd:COG4586 149 DTPVRQLSLG-QRMRCeLAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIV 227
|
250 260 270
....*....|....*....|....*....|.
gi 568976233 1493 MVSGRLRCIGPIQHLKRKFGQDYVLELRVKD 1523
Cdd:COG4586 228 IDHGRIIYDGSLEELKERFGPYKTIVLELAE 258
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
478-691 |
5.29e-41 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 150.72 E-value: 5.29e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM--QDLKEIR 555
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLseKELAAFR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 -KAIG-VCPQHNVqFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDP 633
Cdd:cd03255 81 rRHIGfVFQSFNL-LPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 634 QILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADiLADRKVLIANGAL 691
Cdd:cd03255 160 KIILADEPTGNLDSETGKEVMELLRElnKEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
1280-1499 |
1.37e-39 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 146.59 E-value: 1.37e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1280 SCLHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrLSSAVGHQGDS 1359
Cdd:cd03268 4 NDLTKTYGKKR-----------VLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITF--DGKSYQKNIEA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1360 RAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDavvaISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSP 1439
Cdd:cd03268 71 LRRIGALIEAPGFYPNLTARENLRLLARLLGIRKKR----IDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPD 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1440 VLILDEPSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLR 1499
Cdd:cd03268 147 LLILDEPTNGLDPDGIKELRELILS-LRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
497-643 |
2.30e-39 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 143.56 E-value: 2.30e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKAIGVCPQHNVQFDALTVKEN 576
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTD-DERKSLRKEIGYVFQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 577 LTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAE----HLSEGQKRKLTFGIATVGDPQILLLDEPTV 643
Cdd:pfam00005 80 LRLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
1277-1499 |
2.93e-39 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 145.80 E-value: 2.93e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1277 IIASCLHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGeILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSsaVGHQ 1356
Cdd:cd03264 1 LQLENLTKRYGKKR-----------ALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQD--VLKQ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 GDS-RAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSIL 1435
Cdd:cd03264 67 PQKlRRRIGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALV 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1436 GNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDneKGVLLSTHDLAEAEALCDRAAIMVSGRLR 1499
Cdd:cd03264 147 GDPSILIVDEPTAGLDPEERIRFRNLLSELGED--RIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1293-1485 |
8.36e-39 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 144.16 E-value: 8.36e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1293 CCSRRTRnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkRLSSAVGHQGDSRAEFGYCPQENGL 1372
Cdd:COG4133 9 SCRRGER-LLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLW-NGEPIRDAREDYRRRLAYLGHADGL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1373 WPNLTVKEHLELYAAVKGLRKEDAvvAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:COG4133 87 KPELTVRENLRFWAALYGLRADRE--AIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDA 164
|
170 180 190
....*....|....*....|....*....|...
gi 568976233 1453 SGKHQVWQAIQAVVkDNEKGVLLSTHDLAEAEA 1485
Cdd:COG4133 165 AGVALLAELIAAHL-ARGGAVLLTTHQPLELAA 196
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
478-691 |
1.13e-38 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 143.90 E-value: 1.13e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNlsdMQDLKEIRKA 557
Cdd:cd03268 1 LKTNDLTKTYGKK----RVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKS---YQKNIEALRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILpqdvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03268 74 IGALIEAPGFYPNLTARENLRLLARLLGIR----KKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLI 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 638 LDEPTVGLDPFS----RQRIwgfLKERRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03268 150 LDEPTNGLDPDGikelRELI---LSLRDQGITVLISSHLLSEIQKVADRIGIINKGKL 204
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
478-701 |
2.66e-38 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 143.49 E-value: 2.66e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ--DLKEIR 555
Cdd:cd03258 2 IELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSgkELRKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQI 635
Cdd:cd03258 82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 636 LLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS--SVFLK 701
Cdd:cd03258 162 LLCDEATSALDPETTQSILALLRDinRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTveEVFAN 231
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
478-690 |
3.39e-38 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 142.23 E-value: 3.39e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlkEIRKA 557
Cdd:COG4133 3 LEAENLSCRR----GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARE--DYRRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDveQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:COG4133 77 LAYLGHADGLKPELTVRENLRFWAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADH-VILFSTQfmDEADILADRKVLIANGA 690
Cdd:COG4133 155 LDEPFTALDAAGVALLAELIAAHLARGgAVLLTTH--QPLELAAARVLDLGDFK 206
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
475-691 |
3.83e-38 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 142.87 E-value: 3.83e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 475 KEAIRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM--QDLK 552
Cdd:COG1136 2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLseRELA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 EIR-KAIGVCPQ-HNVqFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATV 630
Cdd:COG1136 82 RLRrRHIGFVFQfFNL-LPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALV 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADIlADRKVLIANGAL 691
Cdd:COG1136 161 NRPKLILADEPTGNLDSKTGEEVLELLRElnRELGTTIVMVTHDPELAAR-ADRVIRLRDGRI 222
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
478-688 |
1.40e-37 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 141.07 E-value: 1.40e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsDMQDLKEIRKA 557
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLV------DGEPVTGPGPD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03293 75 RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIAN 688
Cdd:cd03293 155 LDEPFSALDALTREQLQEELLDiwRETGKTVLLVTHDIDEAVFLADRVVVLSA 207
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
1277-1498 |
9.55e-37 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 139.39 E-value: 9.55e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1277 IIASCLHKEYA---------GQKKHCCSRRTRNM-AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE- 1345
Cdd:cd03267 1 IEVSNLSKSYRvyskepgliGSLKSLFKRKYREVeALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1346 ------------LKRLSSAVGhqgdsraefgycpQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQL 1413
Cdd:cd03267 81 aglvpwkrrkkfLRRIGVVFG-------------QKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1414 NVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIM 1493
Cdd:cd03267 148 DTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVI 227
|
....*
gi 568976233 1494 VSGRL 1498
Cdd:cd03267 228 DKGRL 232
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
478-689 |
6.27e-36 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 136.86 E-value: 6.27e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ--DLKEIR 555
Cdd:cd03261 1 IELRGLTKSFGGR----TVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSeaELYRLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHNVQFDALTVKENLTLFAKIKGILPqdvEQEVQQILSE-LDMQNIRDDL----AEhLSEGQKRKLTFGIATV 630
Cdd:cd03261 77 RRMGMLFQSGALFDSLTVFENVAFPLREHTRLS---EEEIREIVLEkLEAVGLRGAEdlypAE-LSGGMKKRVALARALA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGF---LKERRADHVILFSTQfMDEADILADRKVLIANG 689
Cdd:cd03261 153 LDPELLLYDEPTAGLDPIASGVIDDLirsLKKELGLTSIMVTHD-LDTAFAIADRIAVLYDG 213
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
478-706 |
8.73e-36 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 137.56 E-value: 8.73e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:TIGR04520 1 IEVENVSFSYPE--SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEENLWEIRKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQH--NvQFDALTVK-------ENLtlfakikGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLtfGIA 628
Cdd:TIGR04520 79 VGMVFQNpdN-QFVGATVEddvafglENL-------GVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRV--AIA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 629 TV--GDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEAdILADRKVLIANGALKCTGS--SVFLK- 701
Cdd:TIGR04520 149 GVlaMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEgiTVISITHDMEEA-VLADRVIVMNKGKIVAEGTprEIFSQv 227
|
....*...
gi 568976233 702 ---RKWGL 706
Cdd:TIGR04520 228 ellKEIGL 235
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
478-689 |
1.94e-35 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 134.72 E-value: 1.94e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmqdlkEIRKA 557
Cdd:cd03269 1 LEVENVTKRF----GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDI-----AARNR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03269 72 IGYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLI 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03269 152 LDEPFSGLDPVNVELLKDVIRElARAGKTVILSTHQMELVEELCDRVLLLNKG 204
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1303-1497 |
3.91e-35 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 136.86 E-value: 3.91e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRlSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHL 1382
Cdd:PRK13537 23 VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCG-EPVPSRARHARQRVGVVPQFDNLDPDFTVRENL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAI 1462
Cdd:PRK13537 102 LVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERL 181
|
170 180 190
....*....|....*....|....*....|....*
gi 568976233 1463 QAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK13537 182 RSLLARG-KTILLTTHFMEEAERLCDRLCVIEEGR 215
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1303-1497 |
9.73e-35 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 136.88 E-value: 9.73e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrLSSAVGHQGD-SRAEFGYCPQENGLWPNLTVKEH 1381
Cdd:PRK13536 57 VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITV--LGVPVPARARlARARIGVVPQFDNLDLEFTVREN 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQA 1461
Cdd:PRK13536 135 LLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWER 214
|
170 180 190
....*....|....*....|....*....|....*.
gi 568976233 1462 IQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK13536 215 LRSLLARG-KTILLTTHFMEEAERLCDRLCVLEAGR 249
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
478-798 |
1.18e-34 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 145.93 E-value: 1.18e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLsdMQDLKEIRKA 557
Cdd:TIGR01257 1938 LRLNELTKVYSGTSSP--AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI--LTNISDVHQN 2013
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:TIGR01257 2014 MGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVL 2093
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 638 LDEPTVGLDPFSRQRIW----GFLKERRAdhvILFSTQFMDEADILADRKVLIANGALKCTGSSVFLKRKWGLGYHLSLF 713
Cdd:TIGR01257 2094 LDEPTTGMDPQARRMLWntivSIIREGRA---VVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMK 2170
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 714 M-----DETCDSERLTSFINHHIPYAKLKAKTKEKLVYILPlerTSEFPEFFSDLDKYSGQGLM-SYEVSMSTLNDVFLN 787
Cdd:TIGR01257 2171 IkspkdDLLPDLNPVEQFFQGNFPGSVQRERHYNMLQFQVS---SSSLARIFQLLISHKDSLLIeEYSVTQTTLDQVFVN 2247
|
330
....*....|.
gi 568976233 788 LEGEPSTKQDF 798
Cdd:TIGR01257 2248 FAKQQTETYDL 2258
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
478-691 |
4.01e-34 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 131.53 E-value: 4.01e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY-----VPTAGSVTVYNKNLSDMQ-DL 551
Cdd:cd03260 1 IELRDLNVYY----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKDIYDLDvDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 552 KEIRKAIGVCPQHNVQFDAlTVKENLTLFAKIKGILPQDV-EQEVQQILSELDM-QNIRDDL-AEHLSEGQKRKLTFGIA 628
Cdd:cd03260 77 LELRRRVGMVFQKPNPFPG-SIYDNVAYGLRLHGIKLKEElDERVEEALRKAALwDEVKDRLhALGLSGGQQQRLCLARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 629 TVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03260 156 LANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRL 218
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
479-689 |
4.60e-34 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 128.90 E-value: 4.60e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 479 RIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAI 558
Cdd:cd00267 1 EIENLSFRYGGR----TALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKL-PLEELRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVCPQhnvqfdaltvkenltlfakikgilpqdveqevqqilseldmqnirddlaehLSEGQKRKLTFGIATVGDPQILLL 638
Cdd:cd00267 76 GYVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLL 104
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 639 DEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANG 689
Cdd:cd00267 105 DEPTSGLDPASRERLLELLRELAEEGRtVIIVTHDPELAELAADRVIVLKDG 156
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
478-712 |
7.99e-34 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 132.19 E-value: 7.99e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEY-KGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNL--SDMQDLKEI 554
Cdd:TIGR04521 1 IKLKNVSYIYqPGTPFEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDItaKKKKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVC---PQHnvQFDALTVKE-------NLtlfakikGILPQDVEQEVQQILselDMQNIRDDLAEH----LSEGQK 620
Cdd:TIGR04521 81 RKKVGLVfqfPEH--QLFEETVYKdiafgpkNL-------GLSEEEAEERVKEAL---ELVGLDEEYLERspfeLSGGQM 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 621 RKLtfGIATV--GDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:TIGR04521 149 RRV--AIAGVlaMEPEVLILDEPTAGLDPKGRKEILDLFKRlhKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGT 226
|
250
....*....|....*...
gi 568976233 697 S--VFLKRKWGLGYHLSL 712
Cdd:TIGR04521 227 PreVFSDVDELEKIGLDV 244
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
477-696 |
1.40e-33 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 130.48 E-value: 1.40e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM--QDLKEI 554
Cdd:COG1127 5 MIEVRNLTKSF----GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLseKELYEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPqdvEQEVQQILSE-LDMQNIRDdlAEH-----LSEGQKRKLtfGIA 628
Cdd:COG1127 81 RRRIGMLFQGGALFDSLTVFENVAFPLREHTDLS---EAEIRELVLEkLELVGLPG--AADkmpseLSGGMRKRV--ALA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 629 --TVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH---VILFSTQfMDEADILADRKVLIANGALKCTGS 696
Cdd:COG1127 154 raLALDPEILLYDEPTAGLDPITSAVIDELIRELRDELgltSVVVTHD-LDSAFAIADRVAVLADGKIIAEGT 225
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
478-689 |
2.64e-33 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 127.11 E-value: 2.64e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKA 557
Cdd:cd03228 1 IEFKNVSFSYPGRPKPV--LKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDL-DLESLRKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLtlfakikgilpqdveqevqqilseldmqnirddlaehLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03228 78 IAYVPQDPFLFSG-TIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILI 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADiLADRKVLIANG 689
Cdd:cd03228 120 LDEATSALDPETEALILEALRALAKGKTVIVIAHRLSTIR-DADRIIVLDDG 170
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
1304-1498 |
7.18e-33 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 127.24 E-value: 7.18e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQgdSRAEFGYCPQENGLWPNlTVKEH 1381
Cdd:COG4619 17 SPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLdgKPLSAMPPPE--WRRQVAYVPQEPALWGG-TVRDN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDAvvAISRLVNALKL-HDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQ 1460
Cdd:COG4619 94 LPFPFQLRERKFDRE--RALELLERLGLpPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTRRVEE 171
|
170 180 190
....*....|....*....|....*....|....*...
gi 568976233 1461 AIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:COG4619 172 LLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
477-689 |
8.34e-33 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 129.84 E-value: 8.34e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmqdlkEIRK 556
Cdd:COG4152 1 MLELKGLTKRF----GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDP-----EDRR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:COG4152 72 RIGYLPEERGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELL 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANG 689
Cdd:COG4152 152 ILDEPFSGLDPVNVELLKDVIRELAAKGTtVIFSSHQMELVEELCDRIVIINKG 205
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
478-689 |
1.43e-32 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 126.48 E-value: 1.43e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsDMQDLKEIRKA 557
Cdd:cd03259 1 LELKGLSKTY----GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGR---DVTGVPPERRN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03259 74 IGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03259 154 LDEPLSALDAKLREELREELKElqRELGITTIYVTHDQEEALALADRIAVMNEG 207
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
478-689 |
1.51e-32 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 126.78 E-value: 1.51e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:cd03224 1 LEVENLNAGY----GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGilPQDVEQEVQQILSEL-DMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:cd03224 77 IGYVPEGRRIFPELTVEENLLLGAYARR--RAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03224 155 LLDEPSEGLAPKIVEEIFEAIRELRDEGVtILLVEQNARFALEIADRAYVLERG 208
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
477-689 |
2.05e-32 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 129.95 E-value: 2.05e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKSgkvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKeiRK 556
Cdd:PRK13536 41 AIDLAGVSKSYGDKA----VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLA--RA 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQhnvqFDAL----TVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGD 632
Cdd:PRK13536 115 RIGVVPQ----FDNLdlefTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALIND 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 633 PQILLLDEPTVGLDPFSRQRIWGFLKERRA-DHVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK13536 191 PQLLILDEPTTGLDPHARHLIWERLRSLLArGKTILLTTHFMEEAERLCDRLCVLEAG 248
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
478-696 |
2.06e-32 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 126.78 E-value: 2.06e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:cd03219 1 LEVRGLTKRF----GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENL-----------TLFAKIKGILPQDVEQeVQQILSELDMQNIRDDLAEHLSEGQKRKLTFG 626
Cdd:cd03219 77 IGRTFQIPRLFPELTVLENVmvaaqartgsgLLLARARREEREARER-AEELLERVGLADLADRPAGELSYGQQRRLEIA 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 627 IATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILfstqfMDEADI-----LADRKVLIANGALKCTGS 696
Cdd:cd03219 156 RALATDPKLLLLDEPAAGLNPEETEELAELIRElRERGITVL-----LVEHDMdvvmsLADRVTVLDQGRVIAEGT 226
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
478-647 |
4.59e-32 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 129.04 E-value: 4.59e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM--QDLKEIR 555
Cdd:COG1135 2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALseRELRAAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQH-NVqFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLtfGIAT--VGD 632
Cdd:COG1135 82 RKIGMIFQHfNL-LSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRV--GIARalANN 158
|
170
....*....|....*
gi 568976233 633 PQILLLDEPTVGLDP 647
Cdd:COG1135 159 PKVLLCDEATSALDP 173
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
1302-1508 |
1.46e-31 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 123.70 E-value: 1.46e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQgdsRAEFG--YCPQENGLWPNLT 1377
Cdd:cd03224 15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFdgRDITGLPPHE---RARAGigYVPEGRRIFPELT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1378 VKEHLELYAAVKGLRKEDAVVAIsrlVNAL--KLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGK 1455
Cdd:cd03224 92 VEENLLLGAYARRRAKRKARLER---VYELfpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIV 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1456 HQVWQAIQAVvkdNEKG--VLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLK 1508
Cdd:cd03224 169 EEIFEAIREL---RDEGvtILLVEQNARFALEIADRAYVLERGRVVLEGTAAELL 220
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
479-692 |
1.55e-31 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 123.14 E-value: 1.55e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 479 RIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdmqdLKEIRKAI 558
Cdd:cd03226 1 RIENISFSYKKGT---EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIK----AKERRKSI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVCPQH-NVQFDALTVKENLTLFAKIKGilpqDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03226 74 GYVMQDvDYQLFTDSVREELLLGLKELD----AGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 638 LDEPTVGLDPFSRQRIWG-FLKERRADHVILFSTQFMDEADILADRKVLIANGALK 692
Cdd:cd03226 150 FDEPTSGLDYKNMERVGElIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
477-696 |
1.66e-31 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 124.77 E-value: 1.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRK 556
Cdd:COG1120 1 MLEAENLSVGYGGR----PVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASL-SRRELAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKE--------NLTLFAKIKgilPQDvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIA 628
Cdd:COG1120 76 RIAYVPQEPPAPFGLTVRElvalgrypHLGLFGRPS---AED-REAVEEALERTGLEHLADRPVDELSGGERQRVLIARA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 629 TVGDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:COG1120 152 LAQEPPLLLLDEPTSHLDLAHQLEVLELLRRlaRERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
477-689 |
2.84e-31 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 125.69 E-value: 2.84e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdmQDLKEIRK 556
Cdd:PRK13537 7 PIDFRNVEKRY----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVP--SRARHARQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQhnvqFDAL----TVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGD 632
Cdd:PRK13537 81 RVGVVPQ----FDNLdpdfTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVND 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 633 PQILLLDEPTVGLDPFSRQRIWGFLKERRA-DHVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK13537 157 PDVLVLDEPTTGLDPQARHLMWERLRSLLArGKTILLTTHFMEEAERLCDRLCVIEEG 214
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
478-691 |
3.13e-31 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 122.62 E-value: 3.13e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGkvkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKA 557
Cdd:COG4619 1 LELEGLSFRVGGKPI----LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAM-PPPEWRRQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLTLFAKIKGILPQdvEQEVQQILSELDMQN-IRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:COG4619 76 VAYVPQEPALWGG-TVRDNLPFPFQLRERKFD--RERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADH---VILFSTQfMDEADILADRKVLIANGAL 691
Cdd:COG4619 153 LLDEPTSALDPENTRRVEELLREYLAEEgraVLWVSHD-PEQIERVADRVLTLEAGRL 209
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
478-659 |
5.51e-31 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 122.08 E-value: 5.51e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlKEI--- 554
Cdd:COG2884 2 IRFENVSKRYPGG---REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKR-REIpyl 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVCPQ-HNVQFDaLTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLtfGI--ATVG 631
Cdd:COG2884 78 RRRIGVVFQdFRLLPD-RTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRV--AIarALVN 154
|
170 180
....*....|....*....|....*...
gi 568976233 632 DPQILLLDEPTVGLDPFSRQRIWGFLKE 659
Cdd:COG2884 155 RPELLLADEPTGNLDPETSWEIMELLEE 182
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
1303-1448 |
6.87e-31 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 119.29 E-value: 6.87e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHL 1382
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 ELYAAVKGLRKEDAVVAISRLVNALKLHDQLN----VQVQNLVAGATRKLCFVLSILGNSPVLILDEPST 1448
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
454-710 |
7.34e-31 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 131.49 E-value: 7.34e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 454 DLDPELPSDEYFEPVdPEYQGkeAIRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVP 533
Cdd:COG2274 453 DLPPEREEGRSKLSL-PRLKG--DIELENVSFRYPGDSPPV--LDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEP 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 534 TAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFDAlTVKENLTLFAkikgilpQDVEQEvqQILSELDMQNIRDDLAE 613
Cdd:COG2274 528 TSGRILIDGIDLRQI-DPASLRRQIGVVLQDVFLFSG-TIRENITLGD-------PDATDE--EIIEAARLAGLHDFIEA 596
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 614 H--------------LSEGQKRKLtfGIA--TVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQfmDEAD 677
Cdd:COG2274 597 LpmgydtvvgeggsnLSGGQRQRL--AIAraLLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAH--RLST 672
|
250 260 270
....*....|....*....|....*....|....
gi 568976233 678 I-LADRKVLIANGALKCTGSSVFLKRKWGLGYHL 710
Cdd:COG2274 673 IrLADRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
478-689 |
7.45e-31 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 120.37 E-value: 7.45e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM-QDLKEIRK 556
Cdd:cd03229 1 LELKNVSKRY----GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLeDELPPLRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTLfakikgilpqdveqevqqilseldmqnirddlaeHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:cd03229 77 RIGMVFQDFALFPHLTVLENIAL----------------------------------GLSGGQQQRVALARALAMDPDVL 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03229 123 LLDEPTSALDPITRREVRALLKSLQAQLgiTVVLVTHDLDEAARLADRVVVLRDG 177
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
475-691 |
1.07e-30 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 122.06 E-value: 1.07e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 475 KEAIRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynKNLSDMQDLKEI 554
Cdd:cd03267 15 KEPGLIGSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV--AGLVPWKRRKKF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIG-VCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDP 633
Cdd:cd03267 93 LRRIGvVFGQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEP 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 634 QILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03267 173 EILFLDEPTIGLDVVAQENIRNFLKEYNRERgtTVLLTSHYMKDIEALARRVLVIDKGRL 232
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
457-697 |
2.62e-30 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 127.33 E-value: 2.62e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 457 PELPSDEYFEPVDPEyQGKEAIRIRNIKKEYKGKS-GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTA 535
Cdd:COG1123 241 PRLGAARGRAAPAAA-AAEPLLEVRNLSKRYPVRGkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTS 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 536 GSVTVYNKNLSDM--QDLKEIRKAIGVCPQH-NVQFDA-LTVKENLTLFAKIKGILP-QDVEQEVQQILSELDMqniRDD 610
Cdd:COG1123 320 GSILFDGKDLTKLsrRSLRELRRRVQMVFQDpYSSLNPrMTVGDIIAEPLRLHGLLSrAERRERVAELLERVGL---PPD 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 611 LAE---H-LSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHV--ILFSTQFMDEADILADRKV 684
Cdd:COG1123 397 LADrypHeLSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGltYLFISHDLAVVRYIADRVA 476
|
250
....*....|...
gi 568976233 685 LIANGALKCTGSS 697
Cdd:COG1123 477 VMYDGRIVEDGPT 489
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
477-710 |
5.24e-30 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 127.19 E-value: 5.24e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRK 556
Cdd:COG4987 333 SLELEDVSFRYPG--AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDL-DEDDLRR 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDAlTVKENLtLFAKikgilPQDVEQEVQQILS--ELD--MQNIRDDL-------AEHLSEGQKRKLtf 625
Cdd:COG4987 410 RIAVVPQRPHLFDT-TLRENL-RLAR-----PDATDEELWAALErvGLGdwLAALPDGLdtwlgegGRRLSGGERRRL-- 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 626 GIATV--GDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADiLADRKVLIANGALKCTGSSVFLKRK 703
Cdd:COG4987 481 ALARAllRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLE-RMDRILVLEDGRIVEQGTHEELLAQ 559
|
....*..
gi 568976233 704 WGLGYHL 710
Cdd:COG4987 560 NGRYRQL 566
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
478-687 |
7.02e-30 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 119.18 E-value: 7.02e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:cd03218 1 LRAENLSKRYGKR----KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03218 77 IGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 638 LDEPTVGLDPFSR---QRIWGFLKERR-----ADHVILFSTQFMDEADILADRKVLIA 687
Cdd:cd03218 157 LDEPFAGVDPIAVqdiQKIIKILKDRGigvliTDHNVRETLSITDRAYIIYEGKVLAE 214
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1277-1520 |
8.40e-30 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 119.52 E-value: 8.40e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1277 IIASCLHKEYAgqkkhccSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrLSSAVGHQ 1356
Cdd:COG1124 2 LEVRNLSVSYG-------QGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTF--DGRPVTRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 --GDSRAEFGYCPQ--ENGLWPNLTVKEHLELYAAVKGLRKEDAvvAISRLVNALKLHDQLnvqvqnlvagATRK----- 1427
Cdd:COG1124 73 rrKAFRRRVQMVFQdpYASLHPRHTVDRILAEPLRIHGLPDREE--RIAELLEQVGLPPSF----------LDRYphqls 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1428 ------LCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCI 1501
Cdd:COG1124 141 ggqrqrVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEE 220
|
250
....*....|....*....
gi 568976233 1502 GPIQHLKRKFGQDYVLELR 1520
Cdd:COG1124 221 LTVADLLAGPKHPYTRELL 239
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
478-691 |
1.31e-29 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 118.94 E-value: 1.31e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKA 557
Cdd:cd03295 1 IEFENVTKRYGGGK---KAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIRE-QDPVELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDM--QNIRDDLAEHLSEGQKRKLTFGIATVGDPQI 635
Cdd:cd03295 77 IGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 636 LLLDEPTVGLDPFSRQRIWG-FLKERRADH-VILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03295 157 LLMDEPFGALDPITRDQLQEeFKRLQQELGkTIVFVTHDIDEAFRLADRIAIMKNGEI 214
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1290-1498 |
2.98e-29 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 117.22 E-value: 2.98e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1290 KKHCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK---RLSSAVGHQGDSRAEFGYC 1366
Cdd:cd03257 8 SVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDgkdLLKLSRRLRKIRRKEIQMV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1367 PQE--NGLWPNLTVKEHLE--LYAAVKGLRKEDAVVAISRLVNALKLHDQ-LNVQVQNLVAGATRKLCFVLSILGNSPVL 1441
Cdd:cd03257 88 FQDpmSSLNPRMTIGEQIAepLRIHGKLSKKEARKEAVLLLLVGVGLPEEvLNRYPHELSGGQRQRVAIARALALNPKLL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:cd03257 168 IADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
477-696 |
4.60e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 118.17 E-value: 4.60e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRK 556
Cdd:PRK13632 7 MIKVENVSFSYP--NSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK-ENLKEIRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLtfGIATV--GDP 633
Cdd:PRK13632 84 KIGIIFQNpDNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRV--AIASVlaLNP 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 634 QILLLDEPTVGLDPFSRQRIWGFLKERR--ADHVILFSTQFMDEAdILADRKVLIANGALKCTGS 696
Cdd:PRK13632 162 EIIIFDESTSMLDPKGKREIKKIMVDLRktRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGK 225
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
481-689 |
4.81e-29 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 115.73 E-value: 4.81e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 481 RNIKKEYKGKSGKVKA--LKGLFLDIYESQITAILGHSGAGKSSLLNILSGL--YVPTAGSVTVYNKNLsdmqDLKEIRK 556
Cdd:cd03213 7 RNLTVTVKSSPSKSGKqlLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRrtGLGVSGEVLINGRPL----DKRSFRK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTLFAKIKGIlpqdveqevqqilseldmqnirddlaehlSEGQKRKLTFGIATVGDPQIL 636
Cdd:cd03213 83 IIGYVPQDDILHPTLTVRETLMFAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLL 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKeRRAD--HVILFST-QFMDEADILADRKVLIANG 689
Cdd:cd03213 134 FLDEPTSGLDSSSALQVMSLLR-RLADtgRTIICSIhQPSSEIFELFDKLLLLSQG 188
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
477-727 |
9.32e-29 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 118.65 E-value: 9.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYK---GKSGKVKALKGLF--------------LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVT 539
Cdd:COG4586 1 IIEVENLSKTYRvyeKEPGLKGALKGLFrreyreveavddisFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 540 VYNKNLSdmQDLKEIRKAIGVcpqhnV--Q-----FDaLTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLA 612
Cdd:COG4586 81 VLGYVPF--KRRKEFARRIGV-----VfgQrsqlwWD-LPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLDTPV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 613 EHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDeaDI--LADRKVLIAN 688
Cdd:COG4586 153 RQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERgtTILLTSHDMD--DIeaLCDRVIVIDH 230
|
250 260 270
....*....|....*....|....*....|....*....
gi 568976233 689 GALKCTGSSVFLKRKWGLGYHLSLFMDETCDSERLTSFI 727
Cdd:COG4586 231 GRIIYDGSLEELKERFGPYKTIVLELAEPVPPLELPRGG 269
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
1302-1502 |
1.14e-28 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 115.31 E-value: 1.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDsraeFGYCPQENGLWPNLTVK 1379
Cdd:cd03259 15 ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIdgRDVTGVPPERRN----IGMVFQDYALFPHLTVA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVW 1459
Cdd:cd03259 91 ENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELR 170
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 568976233 1460 QAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03259 171 EELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
477-689 |
1.15e-28 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 116.34 E-value: 1.15e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsdmqDLKEIRK 556
Cdd:COG1121 6 AIELENLTVSY----GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK------PPRRARR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHnVQFDA---LTVKE--NLTLFAKIK--GILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIAT 629
Cdd:COG1121 76 RIGYVPQR-AEVDWdfpITVRDvvLMGRYGRRGlfRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARAL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 630 VGDPQILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:COG1121 155 AQDPDLLLLDEPFAGVDAATEEALYELLRElRREGKTILVVTHDLGAVREYFDRVLLLNRG 215
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
479-666 |
1.45e-28 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 116.29 E-value: 1.45e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 479 RIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAI 558
Cdd:COG0411 6 EVRGLTKRF----GGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIARLGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVCPQHNVQFDALTVKENLTL---------FAKIKGILP------QDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKL 623
Cdd:COG0411 82 ARTFQNPRLFPELTVLENVLVaaharlgrgLLAALLRLPrarreeREARERAEELLERVGLADRADEPAGNLSYGQQRRL 161
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 568976233 624 TFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVI 666
Cdd:COG0411 162 EIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGI 204
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1303-1503 |
2.14e-28 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 115.91 E-value: 2.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAvghqgdSRAEF----GYCPQENGLWPNL 1376
Cdd:COG1120 17 LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLdgRDLASL------SRRELarriAYVPQEPPAPFGL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKE--------HLELYAavkGLRKED--AVVAISRLVNALKLHDQLnvqVQNL---------VAGAtrklcfvlsILGN 1437
Cdd:COG1120 91 TVRElvalgrypHLGLFG---RPSAEDreAVEEALERTGLEHLADRP---VDELsggerqrvlIARA---------LAQE 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1438 SPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:COG1120 156 PPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
1302-1497 |
3.11e-28 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 111.95 E-value: 3.11e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQenglwpnltvkeh 1381
Cdd:cd00267 14 ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQ------------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 lelyaavkglrkedavvaisrlvnalklhdqlnvqvqnLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQA 1461
Cdd:cd00267 81 --------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLEL 122
|
170 180 190
....*....|....*....|....*....|....*.
gi 568976233 1462 IQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:cd00267 123 LRELAEEG-RTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
477-689 |
5.14e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 115.22 E-value: 5.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRK 556
Cdd:PRK13647 4 IIEVEDLHFRYKDGT---KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNA-ENEKWVRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLtfGIATV--GDP 633
Cdd:PRK13647 80 KVGLVFQDpDDQVFSSTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRV--AIAGVlaMDP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 634 QILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK13647 158 DVIVLDEPMAYLDPRGQETLMEILDRlHNQGKTVIVATHDVDLAAEWADQVIVLKEG 214
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
477-696 |
5.88e-28 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 120.39 E-value: 5.88e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTA---GSVTVYNKNLSDMqDLKE 553
Cdd:COG1123 4 LLEVRDLSVRYPG--GDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLDGRDLLEL-SEAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 IRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGD 632
Cdd:COG1123 81 RGRRIGMVFQDpMTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 633 PQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:COG1123 161 PDLLIADEPTTALDVTTQAEILDLLRElqRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGP 226
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
478-703 |
6.86e-28 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 116.82 E-value: 6.86e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS--DMQDLKEIR 555
Cdd:PRK11153 2 IELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTalSEKELRKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHnvqFDAL---TVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLtfGIATV-- 630
Cdd:PRK11153 82 RQIGMIFQH---FNLLssrTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRV--AIARAla 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTG--SSVFLKRK 703
Cdd:PRK11153 157 SNPKVLLCDEATSALDPATTRSILELLKDinRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGtvSEVFSHPK 233
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
477-682 |
8.81e-28 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 114.00 E-value: 8.81e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ--DLKEI 554
Cdd:COG3638 2 MLELRNLSKRY---PGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRgrALRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVCPQhnvQF---DALTVKEN--------LTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKL 623
Cdd:COG3638 79 RRRIGMIFQ---QFnlvPRLSVLTNvlagrlgrTSTWRSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRV 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 624 tfGIAT--VGDPQILLLDEPTVGLDPFSRQRIWGFLKE-RRADHV-ILFSTQFMDEADILADR 682
Cdd:COG3638 156 --AIARalVQEPKLILADEPVASLDPKTARQVMDLLRRiAREDGItVVVNLHQVDLARRYADR 216
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
478-682 |
1.03e-27 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 112.98 E-value: 1.03e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQD--LKEIR 555
Cdd:cd03257 2 LEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRrlRKIRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQhnvqfDA-------LTVKENLTLFAKIKGILPQDVEQEVQQILsELDMQNIRDDLAE----HLSEGQKRKLT 624
Cdd:cd03257 82 KEIQMVFQ-----DPmsslnprMTIGEQIAEPLRIHGKLSKKEARKEAVLL-LLVGVGLPEEVLNryphELSGGQRQRVA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 625 FGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADR 682
Cdd:cd03257 156 IARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELglTLLFITHDLGVVAKIADR 215
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
492-695 |
1.08e-27 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 112.24 E-value: 1.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqdlkeiRKAIGVCPQH-NVQFDA 570
Cdd:cd03235 10 GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE------RKRIGYVPQRrSIDRDF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 571 -LTVKE----NLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGL 645
Cdd:cd03235 84 pISVRDvvlmGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGV 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568976233 646 DPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIaNGALKCTG 695
Cdd:cd03235 164 DPKTQEDIYELLRElRREGMTILVVTHDLGLVLEYFDRVLLL-NRTVVASG 213
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1215-1507 |
1.49e-27 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 119.24 E-value: 1.49e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1215 RCLELKYGKNVVRRDP--IFRiAPQSLKAQPNPEEPidedenvqaerlrtSDALSTPNLDEKPVIIASCLHKEYAGQKKH 1292
Cdd:COG1123 212 RVVVMDDGRIVEDGPPeeILA-APQALAAVPRLGAA--------------RGRAAPAAAAAEPLLEVRNLSKRYPVRGKG 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1293 ccsrrtRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQ-GDSRAEFGYCPQ- 1368
Cdd:COG1123 277 ------GVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFdgKDLTKLSRRSlRELRRRVQMVFQd 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1369 -ENGLWPNLTVKEHLELYAAVKGLRKEDAVVAisRLVNALKlhdqlnvQVQnLVAGATRKLCFVLS------------IL 1435
Cdd:COG1123 351 pYSSLNPRMTVGDIIAEPLRLHGLLSRAERRE--RVAELLE-------RVG-LPPDLADRYPHELSggqrqrvaiaraLA 420
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1436 GNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:COG1123 421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEV 492
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
1302-1497 |
1.79e-27 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 110.74 E-value: 1.79e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDSRAEFGYCPQENGLWPNLTVK 1379
Cdd:cd03229 15 VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIdgEDLTDLEDELPPLRRRIGMVFQDFALFPHLTVL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EHLELyaavkGL------RkedavVAISRlvnalklhdqlnvqvqnlvagatrklcfvlSILGNSPVLILDEPSTGLDVS 1453
Cdd:cd03229 95 ENIAL-----GLsggqqqR-----VALAR------------------------------ALAMDPDVLLLDEPTSALDPI 134
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 568976233 1454 GKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:cd03229 135 TRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
477-696 |
2.36e-27 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 112.43 E-value: 2.36e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEirK 556
Cdd:cd03296 2 SIEVRNVSKRF----GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDV-PVQE--R 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSEL----DMQNIRDDLAEHLSEGQKRKLTFGIATVGD 632
Cdd:cd03296 75 NVGFVFQHYALFRHMTVFDNVAFGLRVKPRSERPPEAEIRAKVHELlklvQLDWLADRYPAQLSGGQRQRVALARALAVE 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 633 PQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:cd03296 155 PKVLLLDEPFGALDAKVRKELRRWLRRlhDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
478-696 |
2.47e-27 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 111.95 E-value: 2.47e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsDMQDLKEIRKA 557
Cdd:cd03300 1 IELENVSKFY----GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGK---DITNLPPHKRP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03300 74 VNTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:cd03300 154 LDEPLGALDLKLRKDMQLELKRlqKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
1302-1502 |
2.88e-27 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 111.09 E-value: 2.88e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLssavgHQGDSRAEFGYCPQ-ENGLW--PnLTV 1378
Cdd:cd03235 14 VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK-----PLEKERKRIGYVPQrRSIDRdfP-ISV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KE--------HLELYAAVKGLRKEDAVVAISRlVNALKLHDQlnvQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGL 1450
Cdd:cd03235 88 RDvvlmglygHKGLFRRLSKADKAKVDEALER-VGLSELADR---QIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGV 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1451 DVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRaAIMVSGRLRCIG 1502
Cdd:cd03235 164 DPKTQEDIYELLRE-LRREGMTILVVTHDLGLVLEYFDR-VLLLNRTVVASG 213
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1295-1504 |
4.23e-27 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 111.71 E-value: 4.23e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1295 SRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-RLSSAVGHQGdsraefgycpqenGLW 1373
Cdd:COG1134 34 TRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNgRVSALLELGA-------------GFH 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVKEHLELYAAVKGL------RKEDAVVAISRlvnalkLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEP- 1446
Cdd:COG1134 101 PELTGRENIYLNGRLLGLsrkeidEKFDEIVEFAE------LGDFIDQPVKTYSSGMRARLAFAVATAVDPDILLVDEVl 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1447 STGlDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPI 1504
Cdd:COG1134 175 AVG-DAAFQKKCLARIRELRESG-RTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDP 230
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
478-691 |
4.40e-27 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 110.58 E-value: 4.40e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQD--LKEIR 555
Cdd:cd03292 1 IEFINVTKTY---PNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGraIPYLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQI 635
Cdd:cd03292 78 RKIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTI 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 636 LLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03292 158 LIADEPTGNLDPDTTWEIMNLLKKiNKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
492-676 |
5.79e-27 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 109.43 E-value: 5.79e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS-DMQDLKEIRKAIGVCPQH-NVQFD 569
Cdd:TIGR01166 3 GGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDySRKGLLERRQRVGLVFQDpDDQLF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 570 ALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFS 649
Cdd:TIGR01166 83 AADVDQDVAFGPLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDPAG 162
|
170 180
....*....|....*....|....*....
gi 568976233 650 RQRIWGFLKERRAD--HVIlFSTQFMDEA 676
Cdd:TIGR01166 163 REQMLAILRRLRAEgmTVV-ISTHDVDLA 190
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
492-697 |
7.14e-27 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 110.84 E-value: 7.14e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQ-HNVqFDA 570
Cdd:COG0410 14 GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLGIGYVPEgRRI-FPS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 571 LTVKENLTLFAKIKGIlPQDVEQEVQQI------LSELdmqniRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVG 644
Cdd:COG0410 93 LTVEENLLLGAYARRD-RAEVRADLERVyelfprLKER-----RRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLG 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 645 LDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANGALKCTGSS 697
Cdd:COG0410 167 LAPLIVEEIFEIIRRLNREGVtILLVEQNARFALEIADRAYVLERGRIVLEGTA 220
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
1302-1497 |
7.63e-27 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 109.86 E-value: 7.63e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQEnglwP-----NL 1376
Cdd:cd03225 16 ALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLVFQN----PddqffGP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCfVLSIL-GNSPVLILDEPSTGLDVSGK 1455
Cdd:cd03225 92 TVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVA-IAGVLaMDPDILLLDEPTAGLDPAGR 170
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1456 HQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:cd03225 171 RELLELLKK-LKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
1282-1498 |
8.85e-27 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 109.89 E-value: 8.85e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQKkhccsrrTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDS 1359
Cdd:cd03255 6 LSKTYGGGG-------EKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVdgTDISKLSEKELAA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1360 --RAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNL-------VAGAtRklcf 1430
Cdd:cd03255 79 frRRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELsggqqqrVAIA-R---- 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1431 vlSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLaEAEALCDRAAIMVSGRL 1498
Cdd:cd03255 154 --ALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDP-ELAEYADRIIELRDGKI 218
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1274-1507 |
1.02e-26 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 116.54 E-value: 1.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1274 KPVIIASCLHKEYAGQKKHccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTA---GQVELKRLS 1350
Cdd:COG1123 2 TPLLEVRDLSVRYPGGDVP---------AVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLDGRD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1351 SAVGHQGDSRAEFGYCPQE--NGLWPnLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKL 1428
Cdd:COG1123 73 LLELSEALRGRRIGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRV 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1429 CFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:COG1123 152 AIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEI 230
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
1287-1502 |
1.43e-26 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 109.54 E-value: 1.43e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1287 AGQKKHCCSRRTRnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-RLSSAVGHQGdsraefgy 1365
Cdd:cd03220 23 LGILGRKGEVGEF-WALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRgRVSSLLGLGG-------- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1366 cpqenGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDE 1445
Cdd:cd03220 94 -----GFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDE 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1446 P-STGlDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03220 169 VlAVG-DAAFQEKCQRRLRELLKQG-KTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
495-691 |
2.03e-26 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 108.92 E-value: 2.03e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 495 KALKGLFLDI---YESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ---DLKEIRKAIGVCPQHNVQF 568
Cdd:cd03297 8 KRLPDFTLKIdfdLNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRkkiNLPPQQRKIGLVFQQYALF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 569 DALTVKENLTLFAKIKGILPQdvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPF 648
Cdd:cd03297 88 PHLNVRENLAFGLKRKRNRED--RISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRA 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 649 SRQRIWGFLKERRADHVI--LFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03297 166 LRLQLLPELKQIKKNLNIpvIFVTHDLSEAEYLADRIVVMEDGRL 210
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
478-695 |
2.24e-26 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 108.50 E-value: 2.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsDMQDLKEIRKA 557
Cdd:cd03301 1 VELENVTKRF----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGR---DVTDLPPKDRD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03301 74 IAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTG 695
Cdd:cd03301 154 MDEPLSNLDAKLRVQMRAELKRlqQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
1277-1498 |
2.51e-26 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 109.17 E-value: 2.51e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1277 IIASCLHKEYagqKKHCcsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK--RLSSAVG 1354
Cdd:cd03218 1 LRAENLSKRY---GKRK--------VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDgqDITKLPM 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1355 HQgDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSI 1434
Cdd:cd03218 70 HK-RARLGIGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARAL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1435 LGNSPVLILDEPSTGLDVSGKHQVwQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:cd03218 149 ATNPKFLLLDEPFAGVDPIAVQDI-QKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKV 211
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
479-695 |
3.29e-26 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 107.14 E-value: 3.29e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 479 RIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAI 558
Cdd:cd03214 1 EVENLSVGYGGR----TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASL-SPKELARKI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVcpqhnvqfdaltvkenltlfakikgilpqdveqeVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLL 638
Cdd:cd03214 76 AY----------------------------------VPQALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLL 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 639 DEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTG 695
Cdd:cd03214 122 DEPTSHLDIAHQIELLELLRRlaRERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
1302-1518 |
3.64e-26 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 108.57 E-value: 3.64e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQ--ENGLWpNLTVK 1379
Cdd:COG1122 16 ALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLVFQnpDDQLF-APTVE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCfVLSILGNSP-VLILDEPSTGLDVSGKHQV 1458
Cdd:COG1122 95 EDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVA-IAGVLAMEPeVLVLDEPTAGLDPRGRREL 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1459 WQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLkrkFGQDYVLE 1518
Cdd:COG1122 174 LELLKRLNKEG-KTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREV---FSDYELLE 229
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
1302-1509 |
4.29e-26 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 108.68 E-value: 4.29e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-----RLSS-AVGHQGDSRAeFgycpQENGLWPN 1375
Cdd:cd03219 15 ALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDgeditGLPPhEIARLGIGRT-F----QIPRLFPE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 LTVKEHLEL---------YAAVKGLRKEDAVVA-ISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDE 1445
Cdd:cd03219 90 LTVLENVMVaaqartgsgLLLARARREEREARErAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDE 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1446 PSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKR 1509
Cdd:cd03219 170 PAAGLNPEETEELAELIRE-LRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
476-689 |
4.81e-26 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 108.63 E-value: 4.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 476 EAIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAG-SVTVYNKNLSDMqDLKEI 554
Cdd:COG1119 2 PLLELRNVTVRRGGK----TILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGE-DVWEL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIG-VCPQHNVQFDA-LTVKEN-LT-LFAKIkgILPQDVEQE----VQQILSELDMQNIRDDLAEHLSEGQKRKLTFG 626
Cdd:COG1119 77 RKRIGlVSPALQLRFPRdETVLDVvLSgFFDSI--GLYREPTDEqrerARELLELLGLAHLADRPFGTLSQGEQRRVLIA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 627 IATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEadILA--DRKVLIANG 689
Cdd:COG1119 155 RALVKDPELLILDEPTAGLDLGARELLLALLDKlaAEGAPTLVLVTHHVEE--IPPgiTHVLLLKDG 219
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
496-696 |
5.95e-26 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 114.86 E-value: 5.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 496 ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFdALTVKE 575
Cdd:COG4988 352 ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDL-DPASWRRQIAWVPQNPYLF-AGTIRE 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 576 NLTLFAkikgilPQDVEQEVQQILSE-------------LDMQnirddLAEH---LSEGQKRKLTFGIATVGDPQILLLD 639
Cdd:COG4988 430 NLRLGR------PDASDEELEAALEAagldefvaalpdgLDTP-----LGEGgrgLSGGQAQRLALARALLRDAPLLLLD 498
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 640 EPTVGLDPFSRQRIWGFLKERRADHVILFSTQfmDEADI-LADRKVLIANGALKCTGS 696
Cdd:COG4988 499 EPTAHLDAETEAEILQALRRLAKGRTVILITH--RLALLaQADRILVLDDGRIVEQGT 554
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
477-691 |
6.05e-26 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 107.68 E-value: 6.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKsgKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRK 556
Cdd:cd03245 2 RIEFRNVSFSYPNQ--EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQL-DPADLRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDAlTVKENLTLF------------AKIKGilpqdVEQEVQQILSELDMQnirddLAEH---LSEGQKR 621
Cdd:cd03245 79 NIGYVPQDVTLFYG-TLRDNITLGapladderilraAELAG-----VTDFVNKHPNGLDLQ-----IGERgrgLSGGQRQ 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 622 KLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADiLADRKVLIANGAL 691
Cdd:cd03245 148 AVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIITHRPSLLD-LVDRIIVMDSGRI 216
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
1298-1498 |
8.88e-26 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 105.98 E-value: 8.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1298 TRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDS-RAEFGYCP---QENGLW 1373
Cdd:cd03215 11 SVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAiRAGIAYVPedrKREGLV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVKEHLelyaavkglrkedavvAISRLvnalklhdqL---NVQvqnlvagatrKLCFVLSILGNSPVLILDEPSTGL 1450
Cdd:cd03215 91 LDLSVAENI----------------ALSSL---------LsggNQQ----------KVVLARWLARDPRVLILDEPTRGV 135
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568976233 1451 DVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:cd03215 136 DVGAKAEIYRLIRELADAG-KAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1302-1498 |
1.21e-25 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 107.82 E-value: 1.21e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-----RLSS-AVGHQGDSRAeFgycpQENGLWPN 1375
Cdd:COG0411 19 AVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDgrditGLPPhRIARLGIART-F----QNPRLFPE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 LTVKEHLEL----------YAAVKGL----RKEDAVVA-ISRLVNALKLHDQLNVQVQNLvAGATRKLcfvLSI---LGN 1437
Cdd:COG0411 94 LTVLENVLVaaharlgrglLAALLRLprarREEREARErAEELLERVGLADRADEPAGNL-SYGQQRR---LEIaraLAT 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1438 SP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:COG0411 170 EPkLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRV 231
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
478-691 |
1.24e-25 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 107.38 E-value: 1.24e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ--DLKEIR 555
Cdd:TIGR02315 2 LEVENLSKVY---PNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRgkKLRKLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHNVQFDALTVKENL---TLFAK--IKGILPQDVEQEVQQILSELDMQNIRD---DLAEHLSEGQKRKLTFGI 627
Cdd:TIGR02315 79 RRIGMIFQHYNLIERLTVLENVlhgRLGYKptWRSLLGRFSEEDKERALSALERVGLADkayQRADQLSGGQQQRVAIAR 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 628 ATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANGAL 691
Cdd:TIGR02315 159 ALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDgiTVIINLHQVDLAKKYADRIVGLKAGEI 224
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
478-689 |
1.37e-25 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 106.46 E-value: 1.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS-DMQDLKEIRK 556
Cdd:cd03262 1 IEIKNLHKSF----GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTdDKKNINELRQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTL-FAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQI 635
Cdd:cd03262 77 KVGMVFQQFNLFPHLTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKV 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 636 LLLDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03262 157 MLFDEPTSALDPELVGEVLDVMKDLAEEGMtMVVVTHEMGFAREVADRVIFMDDG 211
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1304-1486 |
1.48e-25 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 106.11 E-value: 1.48e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK---------RLSSA-VGHQgdsraefgycpqeNGLW 1373
Cdd:PRK13539 19 SGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDggdiddpdvAEACHyLGHR-------------NAMK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVKEHLELYAAVKGLRKEDAVVAIsrlvNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVS 1453
Cdd:PRK13539 86 PALTVAENLEFWAAFLGGEELDIAAAL----EAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAA 161
|
170 180 190
....*....|....*....|....*....|....*..
gi 568976233 1454 GKHQVWQAIQAVVKDNekG-VLLSTH---DLAEAEAL 1486
Cdd:PRK13539 162 AVALFAELIRAHLAQG--GiVIAATHiplGLPGAREL 196
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
492-699 |
1.64e-25 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 106.89 E-value: 1.64e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFDAL 571
Cdd:PRK11614 16 GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRM 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 572 TVKENLTLfakikGILPQDVEQEVQQILSELD----MQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:PRK11614 96 TVEENLAM-----GGFFAERDQFQERIKWVYElfprLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAP 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 648 FSRQRIWGFLKERRADHVILFST-QFMDEADILADRKVLIANG--ALKCTGSSVF 699
Cdd:PRK11614 171 IIIQQIFDTIEQLREQGMTIFLVeQNANQALKLADRGYVLENGhvVLEDTGDALL 225
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
478-696 |
1.73e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 107.86 E-value: 1.73e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS-DMQDLKEIRK 556
Cdd:PRK13639 2 LETRDLKYSYPDGT---EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKyDKKSLLEVRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQH-NVQFDALTVKENLTlFAKIKGILPQD-VEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTF-GIATVgDP 633
Cdd:PRK13639 79 TVGIVFQNpDDQLFAPTVEEDVA-FGPLNLGLSKEeVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIaGILAM-KP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 634 QILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:PRK13639 157 EIIVLDEPTSGLDPMGASQIMKLLYDlNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGT 220
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
478-647 |
1.84e-25 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 107.48 E-value: 1.84e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKE-YKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqdlKEIRK 556
Cdd:COG1101 2 LELKNLSKTfNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKL---PEYKR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 A-----------IGVCPqhnvqfdALTVKENLTLFAK-------IKGILPQDVEqEVQQILSELDM--QNIRDDLAEHLS 616
Cdd:COG1101 79 AkyigrvfqdpmMGTAP-------SMTIEENLALAYRrgkrrglRRGLTKKRRE-LFRELLATLGLglENRLDTKVGLLS 150
|
170 180 190
....*....|....*....|....*....|.
gi 568976233 617 EGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:COG1101 151 GGQRQALSLLMATLTKPKLLLLDEHTAALDP 181
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
1277-1497 |
2.02e-25 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 106.02 E-value: 2.02e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1277 IIASCLHKEYAGqkkhccsRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAvg 1354
Cdd:cd03293 1 LEVRNVSKTYGG-------GGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVdgEPVTGP-- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1355 hqgdsRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSI 1434
Cdd:cd03293 72 -----GPDRGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARAL 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1435 LGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMvSGR 1497
Cdd:cd03293 147 AVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL-SAR 208
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
477-691 |
3.05e-25 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 109.03 E-value: 3.05e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsDMQDLKEIRK 556
Cdd:COG3842 5 ALELENVSKRY----GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGR---DVTGLPPEKR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQK------RkltfgiATV 630
Cdd:COG3842 78 NVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQqrvalaR------ALA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFST--QfmDEADILADRKVLIANGAL 691
Cdd:COG3842 152 PEPRVLLLDEPLSALDAKLREEMREELRRlqRELGITFIYVThdQ--EEALALADRIAVMNDGRI 214
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
1305-1502 |
4.73e-25 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 104.68 E-value: 4.73e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNkGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-RL---SSAVGHQGDSRAEFGYCPQENGLWPNLTVKE 1380
Cdd:cd03297 16 KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNgTVlfdSRKKINLPPQQRKIGLVFQQYALFPHLNVRE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HLElYAAVKGLRKEDAVvAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQ 1460
Cdd:cd03297 95 NLA-FGLKRKRNREDRI-SVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLP 172
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1461 AIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03297 173 ELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
478-692 |
1.18e-24 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 104.02 E-value: 1.18e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgkvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdMQDLKEIRKA 557
Cdd:TIGR03740 1 LETKNLSKRFGKQT----AVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWT-RKDLHKIGSL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNvqfdALTVKENLTLFAKIKGiLPqdvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:TIGR03740 76 IESPPLYE----NLTARENLKVHTTLLG-LP---DSRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLI 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 638 LDEPTVGLDPFS----RQRIWGFLKErraDHVILFSTQFMDEADILADRKVLIANGALK 692
Cdd:TIGR03740 148 LDEPTNGLDPIGiqelRELIRSFPEQ---GITVILSSHILSEVQQLADHIGIISEGVLG 203
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
472-691 |
1.27e-24 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 105.42 E-value: 1.27e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 472 YQGKEAIRIRNI---KKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM 548
Cdd:cd03294 12 KNPQKAFKLLAKgksKEEILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 549 --QDLKEIR-KAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTF 625
Cdd:cd03294 92 srKELRELRrKKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGL 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 626 GIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03294 172 ARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELqkTIVFITHDLDEALRLGDRIAIMKDGRL 239
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1274-1497 |
1.69e-24 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 104.79 E-value: 1.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1274 KPVIIASCLHKEYAgqkkhccSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSS 1351
Cdd:COG1116 5 APALELRGVSKRFP-------TGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVdgKPVTG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1352 AvghqgdsRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLhdqlnvqvqnlvAGATRKLCFV 1431
Cdd:COG1116 78 P-------GPDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGL------------AGFEDAYPHQ 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1432 LS------------ILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMvSGR 1497
Cdd:COG1116 139 LSggmrqrvaiaraLANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL-SAR 215
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
492-691 |
1.85e-24 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 104.47 E-value: 1.85e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLL---NILSGLY--VPTAGSVTVYNKNL-SDMQDLKEIRKAIGVCPQHN 565
Cdd:PRK14239 16 NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLrsiNRMNDLNpeVTITGSIVYNGHNIySPRTDTVDLRKEIGMVFQQP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 566 VQFdALTVKENLTLFAKIKGI-----LPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDE 640
Cdd:PRK14239 96 NPF-PMSIYENVVYGLRLKGIkdkqvLDEAVEKSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARVLATSPKIILLDE 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568976233 641 PTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:PRK14239 175 PTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDL 225
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
478-647 |
2.20e-24 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 103.54 E-value: 2.20e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM-QDLKEIRK 556
Cdd:COG1126 2 IEIENLHKSF----GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSkKDINKLRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQH-NVqFDALTVKENLTLfA--KIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQK------RKLtfgi 627
Cdd:COG1126 78 KVGMVFQQfNL-FPHLTVLENVTL-ApiKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQqrvaiaRAL---- 151
|
170 180
....*....|....*....|
gi 568976233 628 ATvgDPQILLLDEPTVGLDP 647
Cdd:COG1126 152 AM--EPKVMLFDEPTSALDP 169
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
474-696 |
2.37e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 104.78 E-value: 2.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIKKEY-KGKSGKVK-ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDL 551
Cdd:PRK13633 1 MNEMIKCKNVSYKYeSNEESTEKlALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 552 KEIRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKltfgIATV 630
Cdd:PRK13633 81 WDIRNKAGMVFQNpDNQIVATIVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQR----VAIA 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 631 G----DPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEAdILADRKVLIANGALKCTGS 696
Cdd:PRK13633 157 GilamRPECIIFDEPTAMLDPSGRREVVNTIKElnKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGT 227
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
1295-1505 |
2.57e-24 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 103.57 E-value: 2.57e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1295 SRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDSRAEFGYCPQENGLWP 1374
Cdd:cd03299 7 SKDWKEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLN--GKDITNLPPEKRDISYVPQNYALFP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKEHLELyaavkGLRK--------EDAVVAISRLVNALKLhdqLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:cd03299 85 HMTVYKNIAY-----GLKKrkvdkkeiERKVLEIAEMLGIDHL---LNRKPETLSGGEQQRVAIARALVVNPKILLLDEP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1447 STGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQ 1505
Cdd:cd03299 157 FSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPE 215
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
478-689 |
3.09e-24 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 103.42 E-value: 3.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ--DLKEIR 555
Cdd:cd03256 1 IEVENLSKTY---PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKgkALRQLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHNVQFDALTVKENLtLFAK------IKGILPQDVEQEVQQILSELDMQNIRDDL---AEHLSEGQKRKLtfG 626
Cdd:cd03256 78 RQIGMIFQQFNLIERLSVLENV-LSGRlgrrstWRSLFGLFPKEEKQRALAALERVGLLDKAyqrADQLSGGQQQRV--A 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 627 IAT--VGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANG 689
Cdd:cd03256 155 IARalMQQPKLILADEPVASLDPASSRQVMDLLKRINREEgiTVIVSLHQVDLAREYADRIVGLKDG 221
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
482-667 |
3.76e-24 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 102.73 E-value: 3.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 482 NIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLyVP----TAGSVTVYNKNLSDmqdlKEIRKA 557
Cdd:cd03234 8 DVGLKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGR-VEgggtTSGQILFNGQPRKP----DQFQKC 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKgiLP------QDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVG 631
Cdd:cd03234 83 VAYVRQDDILLPGLTVRETLTYTAILR--LPrkssdaIRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLW 160
|
170 180 190
....*....|....*....|....*....|....*...
gi 568976233 632 DPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVIL 667
Cdd:cd03234 161 DPKVLILDEPTSGLDSFTALNLVSTLSQlaRRNRIVIL 198
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
478-712 |
3.88e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 104.33 E-value: 3.88e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSG-KVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS---DMQDLKE 553
Cdd:PRK13634 3 ITFQKVEHRYQYKTPfERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkKNKKLKP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 IRKAIGVC---PQHNVqFDAlTVKENLTLFAKIKGILPQDVEQEVQQIlseLDMQNIRDDLAEH----LSEGQKRKLtfG 626
Cdd:PRK13634 83 LRKKVGIVfqfPEHQL-FEE-TVEKDICFGPMNFGVSEEDAKQKAREM---IELVGLPEELLARspfeLSGGQMRRV--A 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 627 IATV--GDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS--SVFL 700
Cdd:PRK13634 156 IAGVlaMEPEVLVLDEPTAGLDPKGRKEMMEMFYKlhKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTprEIFA 235
|
250
....*....|..
gi 568976233 701 KRKWGLGYHLSL 712
Cdd:PRK13634 236 DPDELEAIGLDL 247
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1302-1503 |
4.16e-24 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 105.95 E-value: 4.16e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQgdsRaEFGYCPQENGLWPNLTVK 1379
Cdd:COG3842 20 ALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLdgRDVTGLPPEK---R-NVGMVFQDYALFPHLTVA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EHLELYAAVKGLRKEDavvaISRLVN-ALKLhdqlnVQVQNLvagATRKlcfV--LSilG-------------NSP-VLI 1442
Cdd:COG3842 96 ENVAFGLRMRGVPKAE----IRARVAeLLEL-----VGLEGL---ADRY---PhqLS--GgqqqrvalaralaPEPrVLL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1443 LDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:COG3842 159 LDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGT 219
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1275-1498 |
4.58e-24 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 102.80 E-value: 4.58e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1275 PVIIASCLHKEYAGqkkhccsrRTrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSA 1352
Cdd:COG1137 2 MTLEAENLVKSYGK--------RT---VVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLdgEDITHL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1353 VGHQgdsRAEFG--YCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKlcf 1430
Cdd:COG1137 71 PMHK---RARLGigYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRR--- 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1431 vLSI---LGNSP-VLILDEPSTGLD---VSGkhqvwqaIQAVV---KDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:COG1137 145 -VEIaraLATNPkFILLDEPFAGVDpiaVAD-------IQKIIrhlKERGIGVLITDHNVRETLGICDRAYIISEGKV 214
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
502-695 |
4.82e-24 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 101.80 E-value: 4.82e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 502 LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynkNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKENLTLfA 581
Cdd:cd03298 19 LTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLI---NGVDVTAAPPADRPVSMLFQENNLFAHLTVEQNVGL-G 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 582 KIKGILPQDVEQE-VQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKER 660
Cdd:cd03298 95 LSPGLKLTAEDRQaIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDL 174
|
170 180 190
....*....|....*....|....*....|....*..
gi 568976233 661 RADH--VILFSTQFMDEADILADRKVLIANGALKCTG 695
Cdd:cd03298 175 HAETkmTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
475-695 |
6.00e-24 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 103.56 E-value: 6.00e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 475 KEAIRIRNIKKEYKGKSGKvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEI 554
Cdd:PRK13635 3 EEIIRVEHISFRYPDAATY--ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSE-ETVWDV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLtfGIATV--G 631
Cdd:PRK13635 80 RRQVGMVFQNpDNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRV--AIAGVlaL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 632 DPQILLLDEPTVGLDPFSRQRIWGF---LKERRADHVILFsTQFMDEAdILADRKVLIANGALKCTG 695
Cdd:PRK13635 158 QPDIIILDEATSMLDPRGRREVLETvrqLKEQKGITVLSI-THDLDEA-AQADRVIVMNKGEILEEG 222
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
478-695 |
6.04e-24 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 100.47 E-value: 6.04e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlkEIRKA 557
Cdd:cd03247 1 LSINNVSFSYPEQEQQV--LKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEK--ALSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAltvkenltlfakikgilpqdveqevqqilseldmqNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03247 77 ISVLNQRPYLFDT-----------------------------------TLRNNLGRRFSGGERQRLALARILLQDAPIVL 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADiLADRKVLIANGALKCTG 695
Cdd:cd03247 122 LDEPTVGLDPITERQLLSLIFEVLKDKTLIWITHHLTGIE-HMDKILFLENGKIIMQG 178
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
478-691 |
7.73e-24 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 102.03 E-value: 7.73e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgkvkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynkNLSDMQDLKEIRKA 557
Cdd:cd03299 1 LKVENLSKDWKEFK-----LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILL---NGKDITNLPPEKRD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03299 73 ISYVPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03299 153 LDEPFSALDVRTKEKLREELKKirKEFGVTVLHVTHDFEEAWALADKVAIMLNGKL 208
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
478-689 |
8.56e-24 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 101.46 E-value: 8.56e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEY------------------KGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVT 539
Cdd:cd03220 1 IELENVSKSYptykggssslkklgilgrKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 540 VyNKNLSDMQDLkeirkaigvcpqhNVQFD-ALTVKENLTLFAKIKGILPQDVEQEVQQIL--SELdmQNIRDDLAEHLS 616
Cdd:cd03220 81 V-RGRVSSLLGL-------------GGGFNpELTGRENIYLNGRLLGLSRKEIDEKIDEIIefSEL--GDFIDLPVKTYS 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 617 EGQKRKLTFGIATVGDPQILLLDEPT-VGlDPFSRQRIWGFLKERRADHVIL-FSTQFMDEADILADRKVLIANG 689
Cdd:cd03220 145 SGMKARLAFAIATALEPDILLIDEVLaVG-DAAFQEKCQRRLRELLKQGKTViLVSHDPSSIKRLCDRALVLEKG 218
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
478-699 |
1.35e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 102.82 E-value: 1.35e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEY-KGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ-DLKEIR 555
Cdd:PRK13637 3 IKIENLTHIYmEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKvKLSDIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVC---PQHnvQFDALTVKENLTLFAKIKGILPQDVEQEVQQILS--ELDMQNIRDDLAEHLSEGQKRKLTFGIATV 630
Cdd:PRK13637 83 KKVGLVfqyPEY--QLFEETIEKDIAFGPINLGLSEEEIENRVKRAMNivGLDYEDYKDKSPFELSGGQKRRVAIAGVVA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANG--ALKCTGSSVF 699
Cdd:PRK13637 161 MEPKILILDEPTAGLDPKGRDEILNKIKElhKEYNMTIILVSHSMEDVAKLADRIIVMNKGkcELQGTPREVF 233
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1274-1498 |
1.86e-23 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 100.50 E-value: 1.86e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1274 KPVIIASCLHKEYAgqkkhccSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKR 1348
Cdd:COG1136 2 SPLLELRNLTKSYG-------TGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVlidgqDISS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1349 LSSavghqgDSRAEF-----GYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNL--- 1420
Cdd:COG1136 75 LSE------RELARLrrrhiGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLsgg 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1421 ----VAGAtRklcfvlSILGNSPVLILDEPsTG-LDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLaEAEALCDRAAIMVS 1495
Cdd:COG1136 149 qqqrVAIA-R------ALVNRPKLILADEP-TGnLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRD 219
|
...
gi 568976233 1496 GRL 1498
Cdd:COG1136 220 GRI 222
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
495-667 |
2.58e-23 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 100.96 E-value: 2.58e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 495 KALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqdlKEIRKA-IGVC-----PqhNVqF 568
Cdd:COG4674 24 KALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGL---DEHEIArLGIGrkfqkP--TV-F 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 569 DALTVKENL------------TLFAKikgiLPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:COG4674 98 EELTVFENLelalkgdrgvfaSLFAR----LTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQDPKLL 173
|
170 180 190
....*....|....*....|....*....|.
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADHVIL 667
Cdd:COG4674 174 LLDEPVAGMTDAETERTAELLKSLAGKHSVV 204
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
496-712 |
3.23e-23 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 101.46 E-value: 3.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 496 ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS-DMQDLKEIRKAIGVC---PQHnvQFDAL 571
Cdd:PRK13636 21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDySRKGLMKLRESVGMVfqdPDN--QLFSA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 572 TVKENLTlFAKIKGILPQD-VEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSR 650
Cdd:PRK13636 99 SVYQDVS-FGAVNLKLPEDeVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGV 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 651 QRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGA--LKCTGSSVFLKRKWGLGYHLSL 712
Cdd:PRK13636 178 SEIMKLLVEmqKELGLTIIIATHDIDIVPLYCDNVFVMKEGRviLQGNPKEVFAEKEMLRKVNLRL 243
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
477-711 |
3.27e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 101.83 E-value: 3.27e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYK-GKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNL---SDMQDLK 552
Cdd:PRK13641 2 SIKFENVDYIYSpGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpeTGNKNLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 EIRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELdmqNIRDDLAEH----LSEGQKRKLTFGI 627
Cdd:PRK13641 82 KLRKKVSLVFQFpEAQLFENTVLKDVEFGPKNFGFSEDEAKEKALKWLKKV---GLSEDLISKspfeLSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 628 ATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGAL--KCTGSSVFLKRKW 704
Cdd:PRK13641 159 VMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDyQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLikHASPKEIFSDKEW 238
|
....*..
gi 568976233 705 GLGYHLS 711
Cdd:PRK13641 239 LKKHYLD 245
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
1296-1502 |
3.94e-23 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 98.28 E-value: 3.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1296 RRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAvghqgdSRAEF----GYCPQe 1369
Cdd:cd03214 8 GYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLdgKDLASL------SPKELarkiAYVPQ- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1370 nglwpnltvkehlelyaavkglrkedavvaISRLVNALKLHDQlnvQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTG 1449
Cdd:cd03214 81 ------------------------------ALELLGLAHLADR---PFNELSGGERQRVLLARALAQEPPILLLDEPTSH 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1450 LDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03214 128 LDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
477-699 |
4.50e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 100.97 E-value: 4.50e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYK-GKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYN---KNLSDMQDLK 552
Cdd:PRK13649 2 GINLQNVSYTYQaGTPFEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDtliTSTSKNKDIK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 EIRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQilsELDMQNIRDDLAE----HLSEGQKRKLTFGI 627
Cdd:PRK13649 82 QIRKKVGLVFQFpESQLFEETVLKDVAFGPQNFGVSQEEAEALARE---KLALVGISESLFEknpfELSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 628 ATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANGALKCTG--SSVF 699
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKlHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGkpKDIF 233
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
478-653 |
6.57e-23 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 99.22 E-value: 6.57e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKA 557
Cdd:cd03254 3 IEFENVNFSYDEK---KPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDI-SRKSLRSM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFdALTVKENLTLFAkikgilPQDVEQEVQQILSELDMQNIRDDL-----------AEHLSEGQKRKLTFG 626
Cdd:cd03254 79 IGVVLQDTFLF-SGTIMENIRLGR------PNATDEEVIEAAKEAGAHDFIMKLpngydtvlgenGGNLSQGERQLLAIA 151
|
170 180
....*....|....*....|....*..
gi 568976233 627 IATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:cd03254 152 RAMLRDPKILILDEATSNIDTETEKLI 178
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
477-647 |
8.68e-23 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 99.32 E-value: 8.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKE--- 553
Cdd:COG4161 2 SIQLKNINCFY----GSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDFSQKPSEkai 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 --IRKAIG-VCPQHNVqFDALTVKENLTLF-AKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIAT 629
Cdd:COG4161 78 rlLRQKVGmVFQQYNL-WPHLTVMENLIEApCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARAL 156
|
170
....*....|....*...
gi 568976233 630 VGDPQILLLDEPTVGLDP 647
Cdd:COG4161 157 MMEPQVLLFDEPTAALDP 174
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1302-1531 |
1.36e-22 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 103.56 E-value: 1.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK----RLSS---AVghqgdsRAEFGYCP---QENG 1371
Cdd:COG1129 267 VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDgkpvRIRSprdAI------RAGIAYVPedrKGEG 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNLTVKEHLELyAAVKGL--------RKEDAVVA--ISRLvnALKLHDqLNVQVQNLVAGATRKLcfVLS--ILGNSP 1439
Cdd:COG1129 341 LVLDLSIRENITL-ASLDRLsrgglldrRRERALAEeyIKRL--RIKTPS-PEQPVGNLSGGNQQKV--VLAkwLATDPK 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1440 VLILDEPSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLrcigpiqhlkrkfgqdyVLEL 1519
Cdd:COG1129 415 VLILDEPTRGIDVGAKAEIYRLIRELAAEG-KAVIVISSELPELLGLSDRILVMREGRI-----------------VGEL 476
|
250
....*....|..
gi 568976233 1520 RVKDVSQEPLVH 1531
Cdd:COG1129 477 DREEATEEAIMA 488
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
1302-1513 |
1.43e-22 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 104.08 E-value: 1.43e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAvghqgDSRAEFGYCPQENGLWpNL 1376
Cdd:COG4987 350 VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSItlggvDLRDLDED-----DLRRRIAVVPQRPHLF-DT 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHL----------ELYAAvkgLRKedavVAISRLVNALKlhDQLNVQV----QNLVAGATRKLCFVLSILGNSPVLI 1442
Cdd:COG4987 424 TLRENLrlarpdatdeELWAA---LER----VGLGDWLAALP--DGLDTWLgeggRRLSGGERRRLALARALLRDAPILL 494
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1443 LDEPSTGLDVSGKHQVWQAIQAVVKDneKGVLLSTHDLAEAEAlCDRAAIMVSGRLRCIGPIQHLKRKFGQ 1513
Cdd:COG4987 495 LDEPTEGLDAATEQALLADLLEALAG--RTVLLITHRLAGLER-MDRILVLEDGRIVEQGTHEELLAQNGR 562
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
1303-1498 |
1.75e-22 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 96.85 E-value: 1.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTA--GQVELKRLSSavgHQGDSRAEFGYCPQENGLWPNLTVKE 1380
Cdd:cd03213 25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGvsGEVLINGRPL---DKRSFRKIIGYVPQDDILHPTLTVRE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HLELYAAVKGLRkedavvaisrlvnalklhdqlnvqvqnlvAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQ 1460
Cdd:cd03213 102 TLMFAAKLRGLS-----------------------------GGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMS 152
|
170 180 190
....*....|....*....|....*....|....*....
gi 568976233 1461 AIQAVVKDNeKGVLLSTHDL-AEAEALCDRAAIMVSGRL 1498
Cdd:cd03213 153 LLRRLADTG-RTIICSIHQPsSEIFELFDKLLLLSQGRV 190
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
477-682 |
1.77e-22 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 103.18 E-value: 1.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNK--NLSDMQDlkEI 554
Cdd:COG3845 5 ALELRGITKRF----GGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKpvRIRSPRD--AI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQD---VEQEVQQILSELDMqNIR-DDLAEHLSEGQKRKLTfgI--A 628
Cdd:COG3845 79 ALGIGMVHQHFMLVPNLTVAENIVLGLEPTKGGRLDrkaARARIRELSERYGL-DVDpDAKVEDLSVGEQQRVE--IlkA 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 629 TVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRAD-HVILFSTQFMDEADILADR 682
Cdd:COG3845 156 LYRGARILILDEPTAVLTPQEADELFEILRRLAAEgKSIIFITHKLREVMAIADR 210
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
1302-1498 |
1.78e-22 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 97.66 E-value: 1.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWpNLTVKEH 1381
Cdd:cd03245 19 ALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGYVPQDVTLF-YGTLRDN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAavkGLRKEDAVVAISRL--VNAL-KLH-DQLNVQV----QNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVS 1453
Cdd:cd03245 98 ITLGA---PLADDERILRAAELagVTDFvNKHpNGLDLQIgergRGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMN 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 1454 GKHQVWQAIQAVVKDneKGVLLSTHDLAeAEALCDRAAIMVSGRL 1498
Cdd:cd03245 175 SEERLKERLRQLLGD--KTLIIITHRPS-LLDLVDRIIVMDSGRI 216
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
477-682 |
2.16e-22 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 98.57 E-value: 2.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY--VPTA---GSVTVYNKNLSDMQ-D 550
Cdd:COG1117 11 KIEVRNLNVYY----GDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNdlIPGArveGEILLDGEDIYDPDvD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 551 LKEIRKAIGVCPQHNVQFdALTVKENLTLFAKIKGILPQD-----VEQ---------EVQQILseldmqnirDDLAEHLS 616
Cdd:COG1117 87 VVELRRRVGMVFQKPNPF-PKSIYDNVAYGLRLHGIKSKSeldeiVEEslrkaalwdEVKDRL---------KKSALGLS 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 617 EGQKRKLTF--GIATvgDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADR 682
Cdd:COG1117 157 GGQQQRLCIarALAV--EPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTHNMQQAARVSDY 222
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
478-691 |
2.43e-22 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 95.19 E-value: 2.43e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsdmqdlkeirka 557
Cdd:cd03216 1 LELRGITKRF----GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILV----------------- 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 igvcpqHNVQFDALTVKEnltlfAKIKGIlpqdveQEVQQilseldmqnirddlaehLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03216 60 ------DGKEVSFASPRD-----ARRAGI------AMVYQ-----------------LSVGERQMVEIARALARNARLLI 105
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANGAL 691
Cdd:cd03216 106 LDEPTAALTPAEVERLFKVIRRLRAQGVaVIFISHRLDEVFEIADRVTVLRDGRV 160
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
454-653 |
2.54e-22 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 103.32 E-value: 2.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 454 DLDPELPSDEYFEPVDPeyqGKEAIRIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVP 533
Cdd:COG1132 319 DEPPEIPDPPGAVPLPP---VRGEIEFENVSFSYPGDR---PVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDP 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 534 TAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFDAlTVKENLTLFAkikgilPQDVEQEVQQIlseLDMQNIRDDLAE 613
Cdd:COG1132 393 TSGRILIDGVDIRDL-TLESLRRQIGVVPQDTFLFSG-TIRENIRYGR------PDATDEEVEEA---AKAAQAHEFIEA 461
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 614 --------------HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:COG1132 462 lpdgydtvvgergvNLSGGQRQRIAIARALLKDPPILILDEATSALDTETEALI 515
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
476-696 |
2.91e-22 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 97.92 E-value: 2.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 476 EAIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM--QDLKE 553
Cdd:PRK13548 1 AMLEARNLSVRLGGR----TLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWspAELAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 IRkaiGVCPQH-NVQFdALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQK------RKLTFG 626
Cdd:PRK13548 77 RR---AVLPQHsSLSF-PFTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQqrvqlaRVLAQL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 627 IATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE---RRADHVILfstqfmdeadIL---------ADRKVLIANGALKCT 694
Cdd:PRK13548 153 WEPDGPPRWLLLDEPTSALDLAHQHHVLRLARQlahERGLAVIV----------VLhdlnlaaryADRIVLLHQGRLVAD 222
|
..
gi 568976233 695 GS 696
Cdd:PRK13548 223 GT 224
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
477-677 |
3.14e-22 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 104.44 E-value: 3.14e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRK 556
Cdd:NF033858 1 VARLEGVSHRY----GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAVCP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQ---HNVQFDaLTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDP 633
Cdd:NF033858 77 RIAYMPQglgKNLYPT-LSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDP 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 568976233 634 QILLLDEPTVGLDPFSRQRIWGFLKERRADHV---ILFSTQFMDEAD 677
Cdd:NF033858 156 DLLILDEPTTGVDPLSRRQFWELIDRIRAERPgmsVLVATAYMEEAE 202
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
478-701 |
3.72e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 98.34 E-value: 3.72e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKA 557
Cdd:PRK13652 4 IETRDLCYSYSGS---KEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITK-ENIREVRKF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:PRK13652 80 VGLVFQNpDDQIFSPTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANGALKCTGS--SVFLK 701
Cdd:PRK13652 160 VLDEPTAGLDPQGVKELIDFLNDlpETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTveEIFLQ 228
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
477-682 |
4.42e-22 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 102.02 E-value: 4.42e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGksgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdMQDLKEIRK 556
Cdd:COG1129 4 LLEMRGISKSFGG----VKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVR-FRSPRDAQA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 A-IGVCPQHNVQFDALTVKENLTL--FAKIKGIL-PQDVEQEVQQILSELDMqNIR-DDLAEHLSEGQK------Rkltf 625
Cdd:COG1129 79 AgIAIIHQELNLVPNLSVAENIFLgrEPRRGGLIdWRAMRRRARELLARLGL-DIDpDTPVGDLSVAQQqlveiaR---- 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 626 giATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADR 682
Cdd:COG1129 154 --ALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQGVaIIYISHRLDEVFEIADR 209
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
1302-1524 |
6.82e-22 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 97.33 E-value: 6.82e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRA----EFGYCPQENGLWPNLT 1377
Cdd:cd03294 39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRElrrkKISMVFQSFALLPHRT 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1378 VKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQ 1457
Cdd:cd03294 119 VLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRRE 198
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1458 VWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLELrVKDV 1524
Cdd:cd03294 199 MQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREF-FRGV 264
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
476-696 |
9.97e-22 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 96.30 E-value: 9.97e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 476 EAIRIRNIKKEY------------------KGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGS 537
Cdd:COG1134 3 SMIEVENVSKSYrlyhepsrslkelllrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 538 VTVyNKNLSDMqdlkeirkaIGVcpqhNVQFDA-LTVKENLTLFAKIKGILPQDVEQEVQQIL--SEL----DMQnIRdd 610
Cdd:COG1134 83 VEV-NGRVSAL---------LEL----GAGFHPeLTGRENIYLNGRLLGLSRKEIDEKFDEIVefAELgdfiDQP-VK-- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 611 laeHLSEGQKRKLTFGIATVGDPQILLLDEPT-VGlDPFSRQRIWGFLKERRADHVILF----STQFMDEadiLADRKVL 685
Cdd:COG1134 146 ---TYSSGMRARLAFAVATAVDPDILLVDEVLaVG-DAAFQKKCLARIRELRESGRTVIfvshSMGAVRR---LCDRAIW 218
|
250
....*....|.
gi 568976233 686 IANGALKCTGS 696
Cdd:COG1134 219 LEKGRLVMDGD 229
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1276-1498 |
1.13e-21 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 95.73 E-value: 1.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1276 VIIASCLHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLS-SAVG 1354
Cdd:PRK10895 3 TLTAKNLAKAYKGRR-----------VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDiSLLP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1355 HQGDSRAEFGYCPQENGLWPNLTVKEHLelyAAVKGLRKEdaVVAISRLVNALKLHDQLNVQV------QNLVAGATRKL 1428
Cdd:PRK10895 72 LHARARRGIGYLPQEASIFRRLSVYDNL---MAVLQIRDD--LSAEQREDRANELMEEFHIEHlrdsmgQSLSGGERRRV 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1429 CFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK10895 147 EIARALAANPKFILLDEPFAGVDPISVIDIKRIIEH-LRDSGLGVLITDHNVRETLAVCERAYIVSQGHL 215
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
502-696 |
1.97e-21 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 97.86 E-value: 1.97e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 502 LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSD---MQDLKEIRKAIGVCPQHNVQFDALTVKENLt 578
Cdd:COG4148 20 FTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDsarGIFLPPHRRRIGYVFQEARLFPHLSVRGNL- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 579 LFAkIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLk 658
Cdd:COG4148 99 LYG-RKRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYL- 176
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 568976233 659 ERRADHV---ILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:COG4148 177 ERLRDELdipILYVSHSLDEVARLADHVVLLEQGRVVASGP 217
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
1304-1509 |
2.40e-21 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 94.88 E-value: 2.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-----RLSSAvgHQGDSRAEFGYCPQENGLWPNLTV 1378
Cdd:cd03261 17 KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDgedisGLSEA--ELYRLRRRMGMLFQSGALFDSLTV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELYAAVKGLRKEDAVVAISRL-VNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQ 1457
Cdd:cd03261 95 FENVAFPLREHTRLSEEEIREIVLEkLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGLDPIASGV 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1458 VWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKR 1509
Cdd:cd03261 175 IDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
497-689 |
3.03e-21 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 94.45 E-value: 3.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsDMQDLKEIRKAIGVCPQHNVQFDALTVKEN 576
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVIL------EGKQITEPGPDRMVVFQNYSLLPWLTVREN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 577 LTLfaKIKGILPQDVEQEVQQILSE-LDMQNIR---DDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQR 652
Cdd:TIGR01184 75 IAL--AVDRVLPDLSKSERRAIVEEhIALVGLTeaaDKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGN 152
|
170 180 190
....*....|....*....|....*....|....*....
gi 568976233 653 IWGFLKERRADH--VILFSTQFMDEADILADRKVLIANG 689
Cdd:TIGR01184 153 LQEELMQIWEEHrvTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1305-1496 |
3.79e-21 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 94.80 E-value: 3.79e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVElkrlssavgHQGDSRaeFGYCPQENGLWPN--LTVKEHL 1382
Cdd:PRK09544 22 DVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK---------RNGKLR--IGYVPQKLYLDTTlpLTVNRFL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 ELYAAVKglrKEDAVVAISRlVNALKLHDQlnvQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAI 1462
Cdd:PRK09544 91 RLRPGTK---KEDILPALKR-VQAGHLIDA---PMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLI 163
|
170 180 190
....*....|....*....|....*....|....*....
gi 568976233 1463 QAVVKDNEKGVLLSTHDL-----AEAEALCDRAAIMVSG 1496
Cdd:PRK09544 164 DQLRRELDCAVLMVSHDLhlvmaKTDEVLCLNHHICCSG 202
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
1302-1502 |
5.61e-21 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 93.09 E-value: 5.61e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDSRAEFgycpQENGLWPNLTVK 1379
Cdd:cd03301 15 ALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIggRDVTDLPPKDRDIAMVF----QNYALYPHMTVY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVW 1459
Cdd:cd03301 91 DNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMR 170
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 568976233 1460 QAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03301 171 AELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
477-647 |
6.62e-21 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 93.54 E-value: 6.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNK--NLSDMQDLKEI 554
Cdd:PRK11124 2 SIQLNGINCFY----GAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfDFSKTPSDKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 ---RKAIG-VCPQHNVqFDALTVKENLTLF-AKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIAT 629
Cdd:PRK11124 78 relRRNVGmVFQQYNL-WPHLTVQQNLIEApCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARAL 156
|
170
....*....|....*...
gi 568976233 630 VGDPQILLLDEPTVGLDP 647
Cdd:PRK11124 157 MMEPQVLLFDEPTAALDP 174
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
440-695 |
7.87e-21 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 98.34 E-value: 7.87e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 440 CFRKTANRNKVIERDLD--PELPSDEYFEpvdpeyQGKEAIRIRNIKKEYKG-KSGKVKALKGLFLDIYESQITAILGHS 516
Cdd:TIGR03269 246 EIKEEGTPDEVVAVFMEgvSEVEKECEVE------VGEPIIKVRNVSKRYISvDRGVVKAVDNVSLEVKEGEIFGIVGTS 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 517 GAGKSSLLNILSGLYVPTAGSVTV-YNKNLSDMQDLK-----EIRKAIGVCPQHNVQFDALTVKENLT---------LFA 581
Cdd:TIGR03269 320 GAGKTTLSKIIAGVLEPTSGEVNVrVGDEWVDMTKPGpdgrgRAKRYIGILHQEYDLYPHRTVLDNLTeaiglelpdELA 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 582 KIKGILPQDVEQevqqiLSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIW-GFLKER 660
Cdd:TIGR03269 400 RMKAVITLKMVG-----FDEEKAEEILDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVThSILKAR 474
|
250 260 270
....*....|....*....|....*....|....*.
gi 568976233 661 RA-DHVILFSTQFMDEADILADRKVLIANGALKCTG 695
Cdd:TIGR03269 475 EEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIG 510
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
478-695 |
8.67e-21 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 98.32 E-value: 8.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:PRK09700 6 ISMAGIGKSF----GPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENL----TLFAKIKGILPQD---VEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATV 630
Cdd:PRK09700 82 IGIIYQELSVIDELTVLENLyigrHLTKKVCGVNIIDwreMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLM 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKERRAD-HVILFSTQFMDEADILADRKVLIANGALKCTG 695
Cdd:PRK09700 162 LDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEgTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG 227
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
482-696 |
8.93e-21 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 93.42 E-value: 8.93e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 482 NIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVC 561
Cdd:PRK10895 8 NLAKAYKGR----RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 562 PQHNVQFDALTVKENLTLFAKIKGILPQDVEQE-VQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDE 640
Cdd:PRK10895 84 PQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDrANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDE 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 641 PTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:PRK10895 164 PFAGVDPISVIDIKRIIEHLRDSGLgVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
492-681 |
1.59e-20 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 93.31 E-value: 1.59e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLL---NILSGLyVPTA---GSVTVYNKNLSDMQ-DLKEIRKAIGVCPQH 564
Cdd:PRK14243 21 GSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILrcfNRLNDL-IPGFrveGKVTFHGKNLYAPDvDPVEVRRRIGMVFQK 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 565 NVQFDAlTVKENLTLFAKI---KGILPQDVEQEVQQILSeldMQNIRDDLAEH---LSEGQKRKLTFGIATVGDPQILLL 638
Cdd:PRK14243 100 PNPFPK-SIYDNIAYGARIngyKGDMDELVERSLRQAAL---WDEVKDKLKQSglsLSGGQQQRLCIARAIAVQPEVILM 175
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 568976233 639 DEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILAD 681
Cdd:PRK14243 176 DEPCSALDPISTLRIEELMHELKEQYTIIIVTHNMQQAARVSD 218
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
1301-1503 |
2.06e-20 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 94.83 E-value: 2.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1301 MAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVgHQGDSRAefGYCPQENGLWPNLTV 1378
Cdd:COG1118 16 TLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLngRDLFTNL-PPRERRV--GFVFQHYALFPHMTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLelyAAvkGLRkedaVVAISRLVNALKLHDQLN-VQVQNL---------------VAGAtRklcfvlsILGNSP-VL 1441
Cdd:COG1118 93 AENI---AF--GLR----VRPPSKAEIRARVEELLElVQLEGLadrypsqlsggqrqrVALA-R-------ALAVEPeVL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:COG1118 156 LLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGT 217
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
445-676 |
2.07e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 92.89 E-value: 2.07e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 445 ANRNKVIErdldpelpsdeyFEPVDPEYQGKEAIRIRNIKkeykgksgkvkalkglfLDIYESQITAILGHSGAGKSSLL 524
Cdd:PRK13648 2 EDKNSIIV------------FKNVSFQYQSDASFTLKDVS-----------------FNIPKGQWTSIVGHNGSGKSTIA 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 525 NILSGLYVPTAGSVtVYNKNLSDMQDLKEIRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELD 603
Cdd:PRK13648 53 KLMIGIEKVKSGEI-FYNNQAITDDNFEKLRKHIGIVFQNpDNQFVGSIVKYDVAFGLENHAVPYDEMHRRVSEALKQVD 131
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 604 MQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEA 676
Cdd:PRK13648 132 MLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHniTIISITHDLSEA 206
|
|
| anch_rpt_ABC |
TIGR03771 |
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ... |
1308-1508 |
2.82e-20 |
|
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 91.45 E-value: 2.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1308 FCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGhqgdsRAEFGYCPQENGL-WPNLTVKEHLEL-- 1384
Cdd:TIGR03771 1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGASPGKG-----WRHIGYVPQRHEFaWDFPISVAHTVMsg 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1385 YAAVKGLRKEDAVVAISRLVNALKlhdqlNVQVQNL-------VAGATRKLCFVLSILGNSP-VLILDEPSTGLDVSGKH 1456
Cdd:TIGR03771 76 RTGHIGWLRRPCVADFAAVRDALR-----RVGLTELadrpvgeLSGGQRQRVLVARALATRPsVLLLDEPFTGLDMPTQE 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1457 QVWQAIQAVVKDnEKGVLLSTHDLAEAEALCDRaAIMVSGRLRCIGPIQHLK 1508
Cdd:TIGR03771 151 LLTELFIELAGA-GTAILMTTHDLAQAMATCDR-VVLLNGRVIADGTPQQLQ 200
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
1305-1523 |
2.93e-20 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 94.40 E-value: 2.93e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKR---LSSAVG-----HQgdsRAeFGYCPQENGLWPNL 1376
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGevlQDSARGiflppHR---RR-IGYVFQEARLFPHL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLeLYAAvKGLRKEDAVVAISRLVNALKLHDQLNVQVQNL-------VAGAtRKLcfvLSilgnSP-VLILDEPST 1448
Cdd:COG4148 93 SVRGNL-LYGR-KRAPRAERRISFDEVVELLGIGHLLDRRPATLsggerqrVAIG-RAL---LS----SPrLLLMDEPLA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1449 GLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQ---------HLKRKFGQDYVLEL 1519
Cdd:COG4148 163 ALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAevlsrpdllPLAGGEEAGSVLEA 242
|
....
gi 568976233 1520 RVKD 1523
Cdd:COG4148 243 TVAA 246
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
478-697 |
3.35e-20 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 91.90 E-value: 3.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY-----VPTAGSVTVYNKNLSDMqDLK 552
Cdd:PRK14247 4 IEIRDLKVSF----GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDIFKM-DVI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 EIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILP--QDVEQEVQQILSELDM-QNIRDDL---AEHLSEGQKRKLTFG 626
Cdd:PRK14247 79 ELRRRVQMVFQIPNPIPNLSIFENVALGLKLNRLVKskKELQERVRWALEKAQLwDEVKDRLdapAGKLSGGQQQRLCIA 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 627 IATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSS 697
Cdd:PRK14247 159 RALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPT 229
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
478-667 |
3.89e-20 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 90.63 E-value: 3.89e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKA 557
Cdd:cd03244 3 IEFKNVSLRYR--PNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKI-GLHDLRSR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLTLF-----AKIKGILpQDV--EQEVQQILSELDMQNIRDDlaEHLSEGQKRKLTFGIATV 630
Cdd:cd03244 80 ISIIPQDPVLFSG-TIRSNLDPFgeysdEELWQAL-ERVglKEFVESLPGGLDTVVEEGG--ENLSVGQRQLLCLARALL 155
|
170 180 190
....*....|....*....|....*....|....*..
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVIL 667
Cdd:cd03244 156 RKSKILVLDEATASVDPETDALIQKTIREAFKDCTVL 192
|
|
| ABC2_membrane_3 |
pfam12698 |
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ... |
31-416 |
4.44e-20 |
|
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.
Pssm-ID: 463674 [Multi-domain] Cd Length: 345 Bit Score: 93.61 E-value: 4.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 31 LLEWSIPIIIGLHMGLFSYLArniqVLEVPPQDLGSLNEFNgsslvvvytpiSNITQQIMNktTFAPTMKGTRIIGVPSI 110
Cdd:pfam12698 5 IITLLLPILLILLLGLIFSNA----VNDPEELPVAVVDEDN-----------SSLSRQLVR--ALEASPTVNLVQYVDSE 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 111 EDLDEVLLHNIPDALGVIFNDsFSYQLKVLRMYGNPFLKEDLLAHcwdthsqafcslskywerGFVALQTAINAGIIEVT 190
Cdd:pfam12698 68 EEAKEALKNGKIDGLLVIPKG-FSKDLLKGESATVTVYINSSNLL------------------VSKLILNALQSLLQQLN 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 191 TNHSVMEELMSIDGINMKT-LPFIPRDLSDYEIFILFCLLYFSSFIYFA--SSNVTKERKQ-CKEVMKVMGLQDSAFWLS 266
Cdd:pfam12698 129 ASALVLLLEALSTSAPIPVeSTPLFNPQSGYAYYLVGLILMIIILIGAAiiAVSIVEEKESrIKERLLVSGVSPLQYWLG 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 267 WGLIYVGFIFIISIFIAIIITSTqIIMMTGFLVIFTLFFLYGLSLIAVTFLMAVLLQKAVLTNLIVLFFTL-FWGCVGFT 345
Cdd:pfam12698 209 KILGDFLVGLLQLLIILLLLFGI-GIPFGNLGLLLLLFLLYGLAYIALGYLLGSLFKNSEDAQSIIGIVILlLSGFFGGL 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 346 VLHKELPPSLEWVLSIFSPFAFTSGMAKVIFQDYNLNgvvfpdpsgesyvMIAVFFILAFDSLLYLVLALY 416
Cdd:pfam12698 288 FPLEDPPSFLQWIFSIIPFFSPIDGLLRLIYGDSLWE-------------IAPSLIILLLFAVVLLLLALL 345
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
513-676 |
4.47e-20 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 97.50 E-value: 4.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 513 LGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLsDMQDLkEIRKAIGVCPQhnvqfdA------LTVKENLTLFAKIKGI 586
Cdd:NF033858 298 LGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPV-DAGDI-ATRRRVGYMSQ------AfslygeLTVRQNLELHARLFHL 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 587 LPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE-RRADHV 665
Cdd:NF033858 370 PAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIElSREDGV 449
|
170
....*....|..
gi 568976233 666 ILF-STQFMDEA 676
Cdd:NF033858 450 TIFiSTHFMNEA 461
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1302-1545 |
6.17e-20 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 95.47 E-value: 6.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK----RLSSAVghqgDSRAEfG----YcpQENGLW 1373
Cdd:COG1129 19 ALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDgepvRFRSPR----DAQAA-GiaiiH--QELNLV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVKE--HLELYAAVKGLRKEDAVVAISR-LVNALKLHDQLNVQVQNL-VagATRKLcfVL---SILGNSPVLILDEP 1446
Cdd:COG1129 92 PNLSVAEniFLGREPRRGGLIDWRAMRRRAReLLARLGLDIDPDTPVGDLsV--AQQQL--VEiarALSRDARVLILDEP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1447 STGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRlrcigpiqhlkrkfgqdYVLELRVKDVSQ 1526
Cdd:COG1129 168 TASLTEREVERLFRIIRR-LKAQGVAIIYISHRLDEVFEIADRVTVLRDGR-----------------LVGTGPVAELTE 229
|
250 260
....*....|....*....|...
gi 568976233 1527 EPLVH----REILKLFPQAARQD 1545
Cdd:COG1129 230 DELVRlmvgRELEDLFPKRAAAP 252
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
450-653 |
6.76e-20 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 95.43 E-value: 6.76e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 450 VIERDLDPELPSDEYFEPVDPeyqgkeAIRIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSG 529
Cdd:TIGR02857 300 VLDAAPRPLAGKAPVTAAPAS------SLEFSGVSVAYPGRR---PALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLG 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 530 LYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFDAlTVKENLtLFAKiKGILPQDVEQEVQQI-LSELDM---Q 605
Cdd:TIGR02857 371 FVDPTEGSIAVNGVPLADA-DADSWRDQIAWVPQHPFLFAG-TIAENI-RLAR-PDASDAEIREALERAgLDEFVAalpQ 446
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568976233 606 NIRDDLAEH---LSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:TIGR02857 447 GLDTPIGEGgagLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEV 497
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
496-686 |
9.90e-20 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 88.83 E-value: 9.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 496 ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsdmqdlkEIRKAIGVCPQHNVQFDAL--TV 573
Cdd:NF040873 7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRR------------AGGARVAYVPQRSEVPDSLplTV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 574 KENLTL--FAKIK--GILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFS 649
Cdd:NF040873 75 RDLVAMgrWARRGlwRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAES 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 568976233 650 RQRIWGFLKERRADHV-ILFSTQFMDEAdILADRKVLI 686
Cdd:NF040873 155 RERIIALLAEEHARGAtVVVVTHDLELV-RRADPCVLL 191
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
478-696 |
1.01e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 91.33 E-value: 1.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKA 557
Cdd:PRK13650 5 IEVKNLTFKYKEDQEKY-TLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTE-ENVWDIRHK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:PRK13650 83 IGMVFQNpDNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKII 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEAdILADRKVLIANGALKCTGS 696
Cdd:PRK13650 163 ILDEATSMLDPEGRLELIKTIKGIRDDYqmTVISITHDLDEV-ALSDRVLVMKNGQVESTST 223
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
495-699 |
1.03e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 91.33 E-value: 1.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 495 KALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYN---KNLSDMQDLKEIRKAIGVCPQH-NVQFDA 570
Cdd:PRK13643 20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDivvSSTSKQKEIKPVRKKVGVVFQFpESQLFE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 571 LTVKENLTLFAKIKGIlpqdVEQEVQQILSE-LDMQNIRDDLAE----HLSEGQKRKLTFGIATVGDPQILLLDEPTVGL 645
Cdd:PRK13643 100 ETVLKDVAFGPQNFGI----PKEKAEKIAAEkLEMVGLADEFWEkspfELSGGQMRRVAIAGILAMEPEVLVLDEPTAGL 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 646 DPFSRQRIWGFLKE-RRADHVILFSTQFMDEADILADRKVLIANG-ALKC-TGSSVF 699
Cdd:PRK13643 176 DPKARIEMMQLFESiHQSGQTVVLVTHLMDDVADYADYVYLLEKGhIISCgTPSDVF 232
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
478-651 |
1.26e-19 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 90.46 E-value: 1.26e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlKEIRKA 557
Cdd:PRK11231 3 LRTENLTVGY----GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSS-RQLARR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKE--------NLTLFakikGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIAT 629
Cdd:PRK11231 78 LALLPQHHLTPEGITVRElvaygrspWLSLW----GRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVL 153
|
170 180
....*....|....*....|..
gi 568976233 630 VGDPQILLLDEPTVGLDpFSRQ 651
Cdd:PRK11231 154 AQDTPVVLLDEPTTYLD-INHQ 174
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
478-696 |
1.31e-19 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 94.35 E-value: 1.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGksgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:PRK15439 12 LCARSISKQYSG----VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHQLG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLtLFAKIKgilPQDVEQEVQQILSELDMQNIRDDLAEHL--SEGQKRKLTFGIatVGDPQI 635
Cdd:PRK15439 88 IYLVPQEPLLFPNLSVKENI-LFGLPK---RQASMQKMKQLLAALGCQLDLDSSAGSLevADRQIVEILRGL--MRDSRI 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 636 LLLDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:PRK15439 162 LILDEPTASLTPAETERLFSRIRELLAQGVgIVFISHKLPEIRQLADRISVMRDGTIALSGK 223
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1272-1509 |
1.37e-19 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 89.65 E-value: 1.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1272 DEKPVIIASCLHKEYAGQKKHccsrrtrnmavRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRL 1349
Cdd:COG1127 1 MSEPMIEVRNLTKSFGDRVVL-----------DGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVdgQDI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1350 SSAVGHQGDS-RAEFGYCPQENGLWPNLTVKEHLELYaavkgLR-----KEDavvAISRLVNaLKLHdqlnvqvqnLV-- 1421
Cdd:COG1127 70 TGLSEKELYElRRRIGMLFQGGALFDSLTVFENVAFP-----LRehtdlSEA---EIRELVL-EKLE---------LVgl 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1422 AGATRKLCFVLS------------ILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDR 1489
Cdd:COG1127 132 PGAADKMPSELSggmrkrvalaraLALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADR 211
|
250 260
....*....|....*....|
gi 568976233 1490 AAIMVSGRLRCIGPIQHLKR 1509
Cdd:COG1127 212 VAVLADGKIIAEGTPEELLA 231
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
1284-1502 |
2.31e-19 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 88.83 E-value: 2.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1284 KEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDSRA 1361
Cdd:cd03300 8 KFYGGFV-----------ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLdgKDITNLPPHKRPVNT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1362 EFgycpQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVL 1441
Cdd:cd03300 77 VF----QNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1442 ILDEPSTGLDVsgkhQVWQAIQAVVKDNEKGV----LLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03300 153 LLDEPLGALDL----KLRKDMQLELKRLQKELgitfVFVTHDQEEALTMSDRIAVMNKGKIQQIG 213
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
478-712 |
2.56e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 90.22 E-value: 2.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEY-KGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSV-----TVYNKnlSDMQDL 551
Cdd:PRK13646 3 IRFDNVSYTYqKGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVtvddiTITHK--TKDKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 552 KEIRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDM-QNIRDDLAEHLSEGQKRKLTFGIAT 629
Cdd:PRK13646 81 RPVRKRIGMVFQFpESQLFEDTVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAIVSIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 630 VGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANGAL--KCTGSSVFLKRKWG 705
Cdd:PRK13646 161 AMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDEnkTIILVSHDMNEVARYADEVIVMKEGSIvsQTSPKELFKDKKKL 240
|
....*..
gi 568976233 706 LGYHLSL 712
Cdd:PRK13646 241 ADWHIGL 247
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
508-689 |
3.03e-19 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 88.66 E-value: 3.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 508 QITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqdlkeirkAIGVCP-----QHNVQFDALTVKENLTLfak 582
Cdd:COG3840 26 ERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTAL--------PPAERPvsmlfQENNLFPHLTVAQNIGL--- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 583 ikGILP-----QDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFL 657
Cdd:COG3840 95 --GLRPglkltAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLV 172
|
170 180 190
....*....|....*....|....*....|....
gi 568976233 658 KERRADH--VILFSTQFMDEADILADRKVLIANG 689
Cdd:COG3840 173 DELCRERglTVLMVTHDPEDAARIADRVLLVADG 206
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
1302-1498 |
3.17e-19 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 86.33 E-value: 3.17e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrlssavghqgdsraefgycpqenglwpnltvkeh 1381
Cdd:cd03216 15 ALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILV----------------------------------- 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 lelyaavkglrkEDAVVAISRLVNALKL-----HdQLNVQVQNLVAGAtRklcfvlSILGNSPVLILDEPSTGLDVSGKH 1456
Cdd:cd03216 60 ------------DGKEVSFASPRDARRAgiamvY-QLSVGERQMVEIA-R------ALARNARLLILDEPTAALTPAEVE 119
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1457 QVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:cd03216 120 RLFKVIRR-LRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
477-696 |
3.37e-19 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 91.30 E-value: 3.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQdLKEIRk 556
Cdd:PRK10851 2 SIEIANIKKSF----GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLH-ARDRK- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 aIGVCPQHNVQFDALTVKENLTLFAKikgILPQ-------DVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIAT 629
Cdd:PRK10851 76 -VGFVFQHYALFRHMTVFDNIAFGLT---VLPRrerpnaaAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARAL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 630 VGDPQILLLDEPTVGLDPFSRQRIWGFLkerRADHVIL-----FSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:PRK10851 152 AVEPQILLLDEPFGALDAQVRKELRRWL---RQLHEELkftsvFVTHDQEEAMEVADRVVVMSQGNIEQAGT 220
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1302-1503 |
3.50e-19 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 90.90 E-value: 3.50e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSS-AVGHQGdsraeFGYCPQENGLWPNLTV 1378
Cdd:COG3839 18 ALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIggRDVTDlPPKDRN-----IAMVFQSYALYPHMTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELYAAVKGLRKEDavvaISRLVNA----LKLHDQLNVQVQNL-------VAgatrklcfvlsiLG-----NSPVLI 1442
Cdd:COG3839 93 YENIAFPLKLRKVPKAE----IDRRVREaaelLGLEDLLDRKPKQLsggqrqrVA------------LGralvrEPKVFL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1443 LDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:COG3839 157 LDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGT 217
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1274-1504 |
4.13e-19 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 92.81 E-value: 4.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1274 KPVIIASCLHKEYAGQkkhccsrrtrnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-----R 1348
Cdd:PRK15439 9 PPLLCARSISKQYSGV-----------EVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGgnpcaR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1349 LSSAVGHQgdsraeFG-Y-CPQENGLWPNLTVKEHLELyaavkGL-RKEDAVVAISRLVNALKLHDQLNVQVQNLVAgAT 1425
Cdd:PRK15439 78 LTPAKAHQ------LGiYlVPQEPLLFPNLSVKENILF-----GLpKRQASMQKMKQLLAALGCQLDLDSSAGSLEV-AD 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1426 RKLCFVL-SILGNSPVLILDEPSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPI 1504
Cdd:PRK15439 146 RQIVEILrGLMRDSRILILDEPTASLTPAETERLFSRIRE-LLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKT 224
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1294-1478 |
5.78e-19 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 86.78 E-value: 5.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1294 CSRRTRnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDS-RAEFGYCPQENGL 1372
Cdd:PRK13538 9 CERDER-ILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQ--GEPIRRQRDEyHQDLLYLGHQPGI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1373 WPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNalkLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:PRK13538 86 KTELTALENLRFYQRLHGPGDDEALWEALAQVG---LAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDK 162
|
170 180
....*....|....*....|....*...
gi 568976233 1453 SGKHQVWQAIQAVVkdnEKG--VLLSTH 1478
Cdd:PRK13538 163 QGVARLEALLAQHA---EQGgmVILTTH 187
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1290-1503 |
6.45e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 92.17 E-value: 6.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1290 KKHCCS-RRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAV-----GHQGDSRAE- 1362
Cdd:TIGR03269 286 SKRYISvDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGDEWVdmtkpGPDGRGRAKr 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1363 -FGYCPQENGLWPNLTVKEHLELYAAVKgLRKEDAVV-AISRLVNA-----------LKLHDQLNVQVQNLVAGAtrklc 1429
Cdd:TIGR03269 366 yIGILHQEYDLYPHRTVLDNLTEAIGLE-LPDELARMkAVITLKMVgfdeekaeeilDKYPDELSEGERHRVALA----- 439
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1430 fvlSILGNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:TIGR03269 440 ---QVLIKEPrIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGD 511
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
451-647 |
6.89e-19 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 92.42 E-value: 6.89e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 451 IERDLDPELPSDEYFEPVD-PEYQGKEAIRIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSG 529
Cdd:TIGR02868 307 IVEVLDAAGPVAEGSAPAAgAVGLGKPTLELRDLSAGYPGAP---PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAG 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 530 LYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFDAlTVKENLtLFAKikgilPQDVEQEVQQILSELDMQN-IR 608
Cdd:TIGR02868 384 LLDPLQGEVTLDGVPVSSL-DQDEVRRRVSVCAQDAHLFDT-TVRENL-RLAR-----PDATDEELWAALERVGLADwLR 455
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 568976233 609 D-------DLAEH---LSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:TIGR02868 456 AlpdgldtVLGEGgarLSGGERQRLALARALLADAPILLLDEPTEHLDA 504
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
1284-1519 |
8.98e-19 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 87.36 E-value: 8.98e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1284 KEYAGQKKhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQ-------------VELKRls 1350
Cdd:cd03295 8 KRYGGGKK----------AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEifidgedireqdpVELRR-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1351 savghqgdsraEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLH---------DQLNVQVQNLV 1421
Cdd:cd03295 76 -----------KIGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDpaefadrypHELSGGQQQRV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1422 aGATRKLCfvlsilGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCI 1501
Cdd:cd03295 145 -GVARALA------ADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQV 217
|
250
....*....|....*...
gi 568976233 1502 GPIQHLKRKFGQDYVLEL 1519
Cdd:cd03295 218 GTPDEILRSPANDFVAEF 235
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
1294-1485 |
9.50e-19 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 86.39 E-value: 9.50e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1294 CSRRTRnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDSRAE-FGYCPQENGL 1372
Cdd:cd03231 8 CERDGR-ALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLN--GGPLDFQRDSIARgLLYLGHAPGI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1373 WPNLTVKEHLELYAAVKGlrKEDAVVAISRlVNALKLHDqlnVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:cd03231 85 KTTLSVLENLRFWHADHS--DEQVEEALAR-VGLNGFED---RPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDK 158
|
170 180 190
....*....|....*....|....*....|....*.
gi 568976233 1453 SGkhqVWQAIQAVVKDNEKG--VLLSTH-DLAEAEA 1485
Cdd:cd03231 159 AG---VARFAEAMAGHCARGgmVVLTTHqDLGLSEA 191
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
474-705 |
9.93e-19 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 89.79 E-value: 9.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAG--KSSLLNILSGlyvPTAGSVTVynKNLSDMQDL 551
Cdd:NF000106 10 ARNAVEVRGLVKHF----GEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPW--RF*TWCANR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 552 KEIRKAIGVC-PQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATV 630
Cdd:NF000106 81 RALRRTIG*HrPVR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMI 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKER-RADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVFLKRKWG 705
Cdd:NF000106 161 GRPAVLYLDEPTTGLDPRTRNEVWDEVRSMvRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG 236
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1302-1498 |
1.04e-18 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 88.96 E-value: 1.04e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKP---TAGQV-----ELKRLSSAvghqgDSRA----EFGYCPQE 1369
Cdd:COG0444 20 AVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEIlfdgeDLLKLSEK-----ELRKirgrEIQMIFQD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1370 --NGLWPNLTVKEHL-ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNV-----------QVQnlvagatRkLCFVLSIL 1435
Cdd:COG0444 95 pmTSLNPVMTVGDQIaEPLRIHGGLSKAEARERAIELLERVGLPDPERRldryphelsggMRQ-------R-VMIARALA 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1436 GNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:COG0444 167 LEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRI 229
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
477-681 |
1.08e-18 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 87.78 E-value: 1.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY-----VPTAGSVTVYNKNLSDMQ-D 550
Cdd:PRK14258 7 AIKVNNLSFYYDTQ----KILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNeleseVRVEGRVEFFNQNIYERRvN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 551 LKEIRKAIG-VCPQHNVQfdALTVKENLTLFAKIKGILPQ-DVEQEVQQILSELDM-QNIRDDL---AEHLSEGQKRKLT 624
Cdd:PRK14258 83 LNRLRRQVSmVHPKPNLF--PMSVYDNVAYGVKIVGWRPKlEIDDIVESALKDADLwDEIKHKIhksALDLSGGQQQRLC 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 625 FGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKER--RADHVILFSTQFMDEADILAD 681
Cdd:PRK14258 161 IARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLrlRSELTMVIVSHNLHQVSRLSD 219
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
481-664 |
1.09e-18 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 85.76 E-value: 1.09e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 481 RNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLyvPTAGSVTvYNKNLSDMQDLKEIRKAIGV 560
Cdd:cd03232 7 KNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGR--KTAGVIT-GEILINGRPLDKNFQRSTGY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 561 CPQHNVQFDALTVKENLTLFAKIKGilpqdveqevqqilseldmqnirddlaehLSEGQKRKLTFGIATVGDPQILLLDE 640
Cdd:cd03232 84 VEQQDVHSPNLTVREALRFSALLRG-----------------------------LSVEQRKRLTIGVELAAKPSILFLDE 134
|
170 180
....*....|....*....|....
gi 568976233 641 PTVGLDPFSRQRIWGFLKeRRADH 664
Cdd:cd03232 135 PTSGLDSQAAYNIVRFLK-KLADS 157
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
478-653 |
1.14e-18 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 87.21 E-value: 1.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKA 557
Cdd:cd03249 1 IEFKNVSFRYPSRPD-VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRD-LNLRWLRSQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLTLfakikGILPQDVEQEVQQILseldMQNIRD---DLAE-----------HLSEGQKRKL 623
Cdd:cd03249 79 IGLVSQEPVLFDG-TIAENIRY-----GKPDATDEEVEEAAK----KANIHDfimSLPDgydtlvgergsQLSGGQKQRI 148
|
170 180 190
....*....|....*....|....*....|
gi 568976233 624 TFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:cd03249 149 AIARALLRNPKILLLDEATSALDAESEKLV 178
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
484-659 |
1.93e-18 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 91.26 E-value: 1.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 484 KKEYKGKSGKVKALKGLFLDI----YESQITAILGHSGAGKSSLLNILSGLY---VPTAGSVTVYNKNLsdmqDLKEIRK 556
Cdd:TIGR00955 24 VSRLRGCFCRERPRKHLLKNVsgvaKPGELLAVMGSSGAGKTTLMNALAFRSpkgVKGSGSVLLNGMPI----DAKEMRA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTLFA--KIKGILPQDVEQE-VQQILSELDMQNIRD------DLAEHLSEGQKRKLTFGI 627
Cdd:TIGR00955 100 ISAYVQQDDLFIPTLTVREHLMFQAhlRMPRRVTKKEKRErVDEVLQALGLRKCANtrigvpGRVKGLSGGERKRLAFAS 179
|
170 180 190
....*....|....*....|....*....|..
gi 568976233 628 ATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE 659
Cdd:TIGR00955 180 ELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKG 211
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
475-691 |
2.28e-18 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 86.43 E-value: 2.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 475 KEAIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY-----VPTAGSVTVYNKNL-SDM 548
Cdd:PRK14267 2 KFAIETVNLRVYY----GSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLelneeARVEGEVRLFGRNIySPD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 549 QDLKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGI------LPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRK 622
Cdd:PRK14267 78 VDPIEVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkskkeLDERVEWALKKAALWDEVKDRLNDYPSNLSGGQRQR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 623 LTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:PRK14267 158 LVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKL 226
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
478-653 |
2.64e-18 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 88.74 E-value: 2.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgkvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsDMQDLKEI--- 554
Cdd:PRK11607 20 LEIRNLTKSFDGQH----AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIML------DGVDLSHVppy 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQ 634
Cdd:PRK11607 90 QRPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPK 169
|
170
....*....|....*....
gi 568976233 635 ILLLDEPTVGLDPFSRQRI 653
Cdd:PRK11607 170 LLLLDEPMGALDKKLRDRM 188
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
477-698 |
2.97e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 86.78 E-value: 2.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGS---VTVYNKNLSDmQDLKE 553
Cdd:PRK13640 5 IVEFKHVSFTYP--DSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTA-KTVWD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 IRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTF-GIATVG 631
Cdd:PRK13640 82 IREKVGIVFQNpDNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIaGILAVE 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 632 dPQILLLDEPTVGLDPFSRQRIWGFLKERRAD-HVILFS-TQFMDEADiLADRKVLIANGALKCTGSSV 698
Cdd:PRK13640 162 -PKIIILDESTSMLDPAGKEQILKLIRKLKKKnNLTVISiTHDIDEAN-MADQVLVLDDGKLLAQGSPV 228
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
1302-1512 |
3.77e-18 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 87.87 E-value: 3.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIrMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEH 1381
Cdd:NF000106 28 AVDGVDLDVREGTVLGVLGP*GAA**RGA-LPAHV*GPDAGRRPWRF*TWCANRRALRRTIG*HRPVR*GRRESFSGREN 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQA 1461
Cdd:NF000106 107 LYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDE 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1462 IQAVVKDNEKgVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFG 1512
Cdd:NF000106 187 VRSMVRDGAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG 236
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
1302-1514 |
4.31e-18 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 90.95 E-value: 4.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrlssaVGHQGDS-----RAEFGYCPQENGLWPNL 1376
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWL------FGQPVDAgdiatRRRVGYMSQAFSLYGEL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKH 1456
Cdd:NF033858 355 TVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARD 434
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1457 QVWQAIQAVVKdnEKGV--LLSTHDLAEAEaLCDRAAIMVSGRLRCIGPIQHLKRKFGQD 1514
Cdd:NF033858 435 MFWRLLIELSR--EDGVtiFISTHFMNEAE-RCDRISLMHAGRVLASDTPAALVAARGAA 491
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
478-696 |
4.75e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 86.19 E-value: 4.75e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:PRK13644 2 IRLENVSYSYPDGT---PALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTF-GIATVgDPQI 635
Cdd:PRK13644 79 VGIVFQNpETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALaGILTM-EPEC 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 636 LLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQFMDEADIlADRKVLIANGALKCTGS 696
Cdd:PRK13644 158 LIFDEVTSMLDPDSGIAVLERIKKlHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGE 218
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1303-1501 |
7.61e-18 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 89.07 E-value: 7.61e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLS---------SAVGHQGDSRaefgycpQENG 1371
Cdd:PRK09700 279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLngKDISprspldavkKGMAYITESR-------RDNG 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNLTVKEHLELYAAVK--------GL---RKEDAVVAISRLVNALKLHdQLNVQVQNLVAGATRKLCFVLSILGNSPV 1440
Cdd:PRK09700 352 FFPNFSIAQNMAISRSLKdggykgamGLfheVDEQRTAENQRELLALKCH-SVNQNITELSGGNQQKVLISKWLCCCPEV 430
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1441 LILDEPSTGLDVSGKHQVWQAIQAVVkDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCI 1501
Cdd:PRK09700 431 IIFDEPTRGIDVGAKAEIYKVMRQLA-DDGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
502-696 |
8.62e-18 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 86.85 E-value: 8.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 502 LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQdlKEI-----RKAIGVCPQHNVQFDALTVKEN 576
Cdd:PRK11144 19 LTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAE--KGIclppeKRRIGYVFQDARLFPHYKVRGN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 577 LTLfakikGILPQDVEQeVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGF 656
Cdd:PRK11144 97 LRY-----GMAKSMVAQ-FDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPY 170
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 568976233 657 LkERRADHV---ILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:PRK11144 171 L-ERLAREInipILYVSHSLDEILRLADRVVVLEQGKVKAFGP 212
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
479-682 |
9.06e-18 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 88.43 E-value: 9.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 479 RIRNIKKEYKGksgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAI 558
Cdd:PRK11288 6 SFDGIGKTFPG----VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAAGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVCPQ--HNVQfdALTVKENLTLfakikGILPQ--------DVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIA 628
Cdd:PRK11288 82 AIIYQelHLVP--EMTVAENLYL-----GQLPHkggivnrrLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKA 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 629 TVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRAD-HVILFSTQFMDEADILADR 682
Cdd:PRK11288 155 LARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEgRVILYVSHRMEEIFALCDA 209
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
497-662 |
1.02e-17 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 83.38 E-value: 1.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNlsdmQDLKEIRKAIGVCPQHNVQFDALTVKEN 576
Cdd:PRK13539 18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGD----IDDPDVAEACHYLGHRNAMKPALTVAEN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 577 LTLFAKIKGILPQDVEQEvqqiLSELDMQNIRDDLAEHLSEGQKRKLtfGIA---TVGDPqILLLDEPTVGLDPFSRQRI 653
Cdd:PRK13539 94 LEFWAAFLGGEELDIAAA----LEAVGLAPLAHLPFGYLSAGQKRRV--ALArllVSNRP-IWILDEPTAALDAAAVALF 166
|
....*....
gi 568976233 654 WGFLKERRA 662
Cdd:PRK13539 167 AELIRAHLA 175
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1302-1544 |
1.03e-17 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 88.55 E-value: 1.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK----RLSS-----AVG----HQgdsraEFgycpq 1368
Cdd:COG3845 20 ANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDgkpvRIRSprdaiALGigmvHQ-----HF----- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1369 enGLWPNLTVKEHLELYAAVKG---LRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDE 1445
Cdd:COG3845 90 --MLVPNLTVAENIVLGLEPTKggrLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILILDE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1446 PSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLrcigpiqhlkrkfgqdyVLELRVKDVS 1525
Cdd:COG3845 168 PTAVLTPQEADELFEILRR-LAAEGKSIIFITHKLREVMAIADRVTVLRRGKV-----------------VGTVDTAETS 229
|
250 260
....*....|....*....|...
gi 568976233 1526 QEPLVH----REILKLFPQAARQ 1544
Cdd:COG3845 230 EEELAElmvgREVLLRVEKAPAE 252
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
1302-1497 |
1.39e-17 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 82.05 E-value: 1.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSsavghQGDSRAEFGYCPQENGLWpNL 1376
Cdd:cd03228 17 VLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEIlidgvDLRDLD-----LESLRKNIAYVPQDPFLF-SG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEhlelyaavkglrkedavvaisrlvnalklhdqlnvqvqNLVAGATR-KLCFVLSILGNSPVLILDEPSTGLDVSGK 1455
Cdd:cd03228 91 TIRE--------------------------------------NILSGGQRqRIAIARALLRDPPILILDEATSALDPETE 132
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1456 HQVWQAIQAVVKDneKGVLLSTHDLAEAEaLCDRAAIMVSGR 1497
Cdd:cd03228 133 ALILEALRALAKG--KTVIVIAHRLSTIR-DADRIIVLDDGR 171
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
497-669 |
1.52e-17 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 84.67 E-value: 1.52e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS-DMQDLKEIRKAIGVCPQH-NVQFDALTVK 574
Cdd:PRK13638 17 LKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDySKRGLLALRQQVATVFQDpEQQIFYTDID 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 575 ENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIW 654
Cdd:PRK13638 97 SDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMI 176
|
170
....*....|....*..
gi 568976233 655 GFLKE--RRADHVILFS 669
Cdd:PRK13638 177 AIIRRivAQGNHVIISS 193
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
451-651 |
1.62e-17 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 87.81 E-value: 1.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 451 IERDLDPELPSDEYFEPVDPEYQGKEAIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL 530
Cdd:COG0488 289 LEREEPPRRDKTVEIRFPPPERLGKKVLELEGLSKSYGDK----TLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGE 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 531 YVPTAGSVTVyNKNLSdmqdlkeirkaIGVCPQHNVQFDaltvkENLTLFAKIKGILPQDVEQEVQQILSEL----DMQn 606
Cdd:COG0488 365 LEPDSGTVKL-GETVK-----------IGYFDQHQEELD-----PDKTVLDELRDGAPGGTEQEVRGYLGRFlfsgDDA- 426
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 607 irDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQ 651
Cdd:COG0488 427 --FKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETLE 469
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
511-689 |
1.62e-17 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 83.48 E-value: 1.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 511 AILGHSGAGKSSLLNILSGLYVPTAGSVTVynkNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKENLTLfakikGILP-- 588
Cdd:PRK10771 29 AILGPSGAGKSTLLNLIAGFLTPASGSLTL---NGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGL-----GLNPgl 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 589 ---QDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE---RRA 662
Cdd:PRK10771 101 klnAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQvcqERQ 180
|
170 180
....*....|....*....|....*..
gi 568976233 663 DHVILFSTQFMDEADIlADRKVLIANG 689
Cdd:PRK10771 181 LTLLMVSHSLEDAARI-APRSLVVADG 206
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
477-689 |
2.08e-17 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 83.98 E-value: 2.08e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKeirk 556
Cdd:PRK11248 1 MLQISHLYADYGGK----PALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 aiGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:PRK11248 73 --GVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLL 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 637 LLDEPTVGLDPFSRQ-------RIWgflkeRRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK11248 151 LLDEPFGALDAFTREqmqtlllKLW-----QETGKQVLLITHDIEEAVFMATELVLLSPG 205
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
448-696 |
2.23e-17 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 87.96 E-value: 2.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 448 NKVIERDLDPELPSDEYFEPVDPeyqgkeAIRIRNIKKEYKGksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNIL 527
Cdd:PRK11160 315 NEITEQKPEVTFPTTSTAAADQV------SLTLNNVSFTYPD--QPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLL 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 528 SGLYVPTAGSVTVYNKNLSDMQDlKEIRKAIGVCPQHNVQFDAlTVKENLTLfAKikgilPQDVEQEVQQILSELDMQNI 607
Cdd:PRK11160 387 TRAWDPQQGEILLNGQPIADYSE-AALRQAISVVSQRVHLFSA-TLRDNLLL-AA-----PNASDEALIEVLQQVGLEKL 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 608 RDD-------LAE---HLSEGQKRKLtfGIATV--GDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFST----- 670
Cdd:PRK11160 459 LEDdkglnawLGEggrQLSGGEQRRL--GIARAllHDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMIThrltg 536
|
250 260
....*....|....*....|....*...
gi 568976233 671 --QFmdeadilaDRKVLIANGALKCTGS 696
Cdd:PRK11160 537 leQF--------DRICVMDNGQIIEQGT 556
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
474-691 |
2.28e-17 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 81.71 E-value: 2.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIkkeykgkSGKvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKE 553
Cdd:cd03215 1 GEPVLEVRGL-------SVK-GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 IRKAIGVCP---QHNVQFDALTVKENLTLfakikgilpqdveqevqqilseldmqnirddlAEHLSEGQKRKLTFGIATV 630
Cdd:cd03215 73 IRAGIAYVPedrKREGLVLDLSVAENIAL--------------------------------SSLLSGGNQQKVVLARWLA 120
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQfMDEADILADRKVLIANGAL 691
Cdd:cd03215 121 RDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGkaVLLISSE-LDELLGLCDRILVMYEGRI 182
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1303-1503 |
2.45e-17 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 86.43 E-value: 2.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL------KRLSSAVGHQGDSraefgyCPQENGLWPNL 1376
Cdd:PRK09536 19 LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVagddveALSARAASRRVAS------VPQDTSLSFEF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLEL----YAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:PRK09536 93 DVRQVVEMgrtpHRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDI 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1453 SgkHQVwQAIQAV--VKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:PRK09536 173 N--HQV-RTLELVrrLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGP 222
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
477-689 |
2.46e-17 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 83.65 E-value: 2.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKSgkvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTV------YNKNLSDMQD 550
Cdd:PRK11264 3 AIEVKNLVKKFHGQT----VLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidTARSLSQQKG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 551 L-KEIRKAIGVCPQHNVQFDALTVKENLTLFAKI-KGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIA 628
Cdd:PRK11264 79 LiRQLRQHVGFVFQNFNLFPHRTVLENIIEGPVIvKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 629 TVGDPQILLLDEPTVGLDP----FSRQRIWGFLKERRAdHVILfsTQFMDEADILADRKVLIANG 689
Cdd:PRK11264 159 LAMRPEVILFDEPTSALDPelvgEVLNTIRQLAQEKRT-MVIV--THEMSFARDVADRAIFMDQG 220
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
484-696 |
2.62e-17 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 86.24 E-value: 2.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 484 KKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQD--LKEIR-KAIGV 560
Cdd:PRK10070 31 KEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDaeLREVRrKKIAM 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 561 CPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDE 640
Cdd:PRK10070 111 VFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDE 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 641 PTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:PRK10070 191 AFSALDPLIRTEMQDELVKLQAKHqrTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGT 248
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1282-1507 |
2.68e-17 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 83.01 E-value: 2.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQKKhccsrrtRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAvgHQ 1356
Cdd:cd03258 7 VSKVFGDTGG-------KVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVlvdgtDLTLLSGK--EL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 GDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKlcfvLSI-- 1434
Cdd:cd03258 78 RKARRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQR----VGIar 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1435 -LGNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:cd03258 154 aLANNPkVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
1303-1496 |
2.81e-17 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 81.92 E-value: 2.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLssavgHQGDSRAEFGYCPQENG--LWPNlTV 1378
Cdd:cd03226 16 LDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLngKPI-----KAKERRKSIGYVMQDVDyqLFTD-SV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEhlELYAAVKGLRKEDAVVA-ISRLVNALKLHDQLNV-----QVQNLVAGATrklcfvlsILGNSPVLILDEPSTGLDV 1452
Cdd:cd03226 90 RE--ELLLGLKELDAGNEQAEtVLKDLDLYALKERHPLslsggQKQRLAIAAA--------LLSGKDLLIFDEPTSGLDY 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 568976233 1453 SGKHQVWQAIQAVVKDnEKGVLLSTHDLAEAEALCDRAAIMVSG 1496
Cdd:cd03226 160 KNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANG 202
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
478-647 |
3.54e-17 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 80.72 E-value: 3.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmQDLKEIRKA 557
Cdd:cd03246 1 LEVENVSFRYPGAEPPV--LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQ-WDPNELGDH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVcpqhnvqfdaltvkenltlfakikgiLPQDVEqevqqILSELDMQNIrddlaehLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03246 78 VGY--------------------------LPQDDE-----LFSGSIAENI-------LSGGQRQRLGLARALYGNPRILV 119
|
170
....*....|
gi 568976233 638 LDEPTVGLDP 647
Cdd:cd03246 120 LDEPNSHLDV 129
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
1305-1498 |
3.89e-17 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 82.32 E-value: 3.89e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAG---ITKPTAGQV-----ELKRlssavgHQgdSRAEFGYCPQENGLWPNL 1376
Cdd:cd03234 25 DVSLHVESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQIlfngqPRKP------DQ--FQKCVAYVRQDDILLPGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLeLYAAVKGLRKE------DAVVAISRLvNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGL 1450
Cdd:cd03234 97 TVRETL-TYTAILRLPRKssdairKKRVEDVLL-RDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1451 DVSGKHQVWQAIQAVVKDNeKGVLLSTH----DLAEaeaLCDRAAIMVSGRL 1498
Cdd:cd03234 175 DSFTALNLVSTLSQLARRN-RIVILTIHqprsDLFR---LFDRILLLSSGEI 222
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1306-1498 |
4.91e-17 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 86.12 E-value: 4.91e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1306 VSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDS-RAEFGYCPQ---ENGLWPNLTVKEH 1381
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAiRAGIMLCPEdrkAEGIIPVHSVADN 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLR----------KEDAVVAISRLvnALKL--HDQLnvqVQNLVAGATRKlcfvlSILG-----NSPVLILD 1444
Cdd:PRK11288 352 INISARRHHLRagclinnrweAENADRFIRSL--NIKTpsREQL---IMNLSGGNQQK-----AILGrwlseDMKVILLD 421
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1445 EPSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK11288 422 EPTRGIDVGAKHEIYNVIYELAAQG-VAVLFVSSDLPEVLGVADRIVVMREGRI 474
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
1310-1489 |
5.21e-17 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 82.46 E-value: 5.21e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1310 VNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAvghqgdsraefgYCPQENGLWPNLTVKEHleLYAAVK 1389
Cdd:cd03237 22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS------------YKPQYIKADYEGTVRDL--LSSITK 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1390 GLRKEDAVvaISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDN 1469
Cdd:cd03237 88 DFYTHPYF--KTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAENN 165
|
170 180
....*....|....*....|
gi 568976233 1470 EKGVLLSTHDLAEAEALCDR 1489
Cdd:cd03237 166 EKTAFVVEHDIIMIDYLADR 185
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
1302-1517 |
5.75e-17 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 86.81 E-value: 5.75e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAvghqgDSRAEFGYCPQENGLWpNL 1376
Cdd:COG2274 490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRIlidgiDLRQIDPA-----SLRRQIGVVLQDVFLF-SG 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAvkgLRKEDAVVAISRLVNAL----KLHDQLNVQV----QNLVAGATRKLCFVLSILGNSPVLILDEPST 1448
Cdd:COG2274 564 TIRENITLGDP---DATDEEIIEAARLAGLHdfieALPMGYDTVVgeggSNLSGGQRQRLAIARALLRNPRILILDEATS 640
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1449 GLDVSGKHQVWQAIQAVVKDneKGVLLSTHDLAEAeALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVL 1517
Cdd:COG2274 641 ALDAETEAIILENLRRLLKG--RTVIIIAHRLSTI-RLADRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
478-653 |
6.05e-17 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 81.89 E-value: 6.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQdLKEIRKA 557
Cdd:cd03251 1 VEFKNVTFRYPGDGPPV--LRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYT-LASLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLTlFAKiKGILPQDVEQ-----EVQQILSELD--MQNIRDDLAEHLSEGQKRKLTFGIATV 630
Cdd:cd03251 78 IGLVSQDVFLFND-TVAENIA-YGR-PGATREEVEEaaraaNAHEFIMELPegYDTVIGERGVKLSGGQRQRIAIARALL 154
|
170 180
....*....|....*....|...
gi 568976233 631 GDPQILLLDEPTVGLDPFSRQRI 653
Cdd:cd03251 155 KDPPILILDEATSALDTESERLV 177
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1302-1498 |
8.39e-17 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 85.46 E-value: 8.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlssavGH--QGDSRAEF-----GYCPQE---NG 1371
Cdd:COG3845 273 ALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLD------GEdiTGLSPRERrrlgvAYIPEDrlgRG 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNLTVKEH--LELYA----AVKGLRKEDAVVAisrlvNALKLHDQLNVQVQNLVAgATRKLC------FVLS--ILGN 1437
Cdd:COG3845 347 LVPDMSVAENliLGRYRrppfSRGGFLDRKAIRA-----FAEELIEEFDVRTPGPDT-PARSLSggnqqkVILAreLSRD 420
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1438 SPVLILDEPSTGLDVSGKHQVWQAIQAVvKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:COG3845 421 PKLLIAAQPTRGLDVGAIEFIHQRLLEL-RDAGAAVLLISEDLDEILALSDRIAVMYEGRI 480
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
1302-1502 |
9.42e-17 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 81.62 E-value: 9.42e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEH 1381
Cdd:cd03296 17 ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFG--GEDATDVPVQERNVGFVFQHYALFRHMTVFDN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDAVVAISRLVNA-LKLhdqlnVQVQNL-------VAGATRKLCFVLSILGNSP-VLILDEPSTGLDV 1452
Cdd:cd03296 95 VAFGLRVKPRSERPPEAEIRAKVHElLKL-----VQLDWLadrypaqLSGGQRQRVALARALAVEPkVLLLDEPFGALDA 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1453 sgkhQVWQAIQAVVKD--NEKGV--LLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:cd03296 170 ----KVRKELRRWLRRlhDELHVttVFVTHDQEEALEVADRVVVMNKGRIEQVG 219
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1282-1502 |
1.07e-16 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 84.12 E-value: 1.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQkkhccsrrtrnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDS 1359
Cdd:PRK11607 25 LTKSFDGQ-----------HAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLdgVDLSHVPPYQRPI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1360 RAEFgycpQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSP 1439
Cdd:PRK11607 94 NMMF----QSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPK 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1440 VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:PRK11607 170 LLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIG 232
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1300-1481 |
1.22e-16 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 80.87 E-value: 1.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLssavghqgdSRAE-------FGYCP 1367
Cdd:COG2884 15 REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVlvngqDLSRL---------KRREipylrrrIGVVF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1368 QENGLWPNLTVKEHLELYAAVKGLRKEDA---VVAISRLVNALKLHDQLNVQV----QNLVAGAtRklcfvlSILGNSPV 1440
Cdd:COG2884 86 QDFRLLPDRTVYENVALPLRVTGKSRKEIrrrVREVLDLVGLSDKAKALPHELsggeQQRVAIA-R------ALVNRPEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 568976233 1441 LILDEPSTGLDVSGKHQVWQAIQAVvkdNEKG--VLLSTHDLA 1481
Cdd:COG2884 159 LLADEPTGNLDPETSWEIMELLEEI---NRRGttVLIATHDLE 198
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
289-664 |
1.57e-16 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 85.93 E-value: 1.57e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 289 TQIIMMTGFLVIFTL----------FFLYGLSLIAVTFLMAVL----------LQKA-VLTNLIVLFFTLFwgcVGFTVL 347
Cdd:TIGR00956 507 FKIIESVVFNIILYFmvnfrrtagrFFFYLLILFICTLAMSHLfrsigavtktLSEAmTPAAILLLALSIY---TGFAIP 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 348 HKELPPSLEWVLSIfSP--FAFTSGMA------KVIFQDYNLNGVVFPDPS-------------GESYVMIAVFFILAFD 406
Cdd:TIGR00956 584 RPSMLGWSKWIYYV-NPlaYAFESLMVnefhgrRFECSQYVPSGGGYDNLGvtnkvctvvgaepGQDYVDGDDYLKLSFQ 662
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 407 S-----------LLYLVLALYFDKILLY----GAEHRSAPLFFLNPTSCFRKTANRN---KVIERDLDPELPSDEYF--- 465
Cdd:TIGR00956 663 YynshkwrnfgiIIGFTVFFFFVYILLTefnkGAKQKGEILVFRRGSLKRAKKAGETsasNKNDIEAGEVLGSTDLTdes 742
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 466 ----EPVDPEYQGKEAIRI-RNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYvpTAGSVTv 540
Cdd:TIGR00956 743 ddvnDEKDMEKESGEDIFHwRNLTYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERV--TTGVIT- 819
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 541 YNKNLSDMQDLKE-IRKAIGVCPQHNVQFDALTVKENLTLFAKIKgiLPQDVEQE-----VQQILSELDMQNIRDDL--- 611
Cdd:TIGR00956 820 GGDRLVNGRPLDSsFQRSIGYVQQQDLHLPTSTVRESLRFSAYLR--QPKSVSKSekmeyVEEVIKLLEMESYADAVvgv 897
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 612 -AEHLSEGQKRKLTFGIATVGDPQILL-LDEPTVGLDPfsrQRIWGFLKERR--ADH 664
Cdd:TIGR00956 898 pGEGLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDS---QTAWSICKLMRklADH 951
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1303-1514 |
2.13e-16 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 80.97 E-value: 2.13e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQ-GDSRAEFgycPQENGLWPNLTVK 1379
Cdd:PRK13548 18 LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLngRPLADWSPAElARRRAVL---PQHSSLSFPFTVE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EhlelyaavkglrkedaVVAISRLVnalklHDQLNVQVQNLVAGA---------------------------TRKLCFVL 1432
Cdd:PRK13548 95 E----------------VVAMGRAP-----HGLSRAEDDALVAAAlaqvdlahlagrdypqlsggeqqrvqlARVLAQLW 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1433 SILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQ------H 1506
Cdd:PRK13548 154 EPDGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAevltpeT 233
|
....*...
gi 568976233 1507 LKRKFGQD 1514
Cdd:PRK13548 234 LRRVYGAD 241
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1307-1507 |
2.44e-16 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 80.18 E-value: 2.44e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1307 SFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrlssavghQGDSRAefGYCP---------QENGLWPNLT 1377
Cdd:COG3840 19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILW---------NGQDLT--ALPPaerpvsmlfQENNLFPHLT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1378 VKEHLELyaavkGLRKedavvaisrlvnALKlhdqLNVQVQNLVAGATRK---------LCFVLS------------ILG 1436
Cdd:COG3840 88 VAQNIGL-----GLRP------------GLK----LTAEQRAQVEQALERvglaglldrLPGQLSggqrqrvalarcLVR 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1437 NSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:COG3840 147 KRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
474-697 |
2.92e-16 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 80.48 E-value: 2.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIKKEYKGKSGKVkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY------VPTAGSVTVYNKNLSD 547
Cdd:PRK14246 4 GKSAEDVFNISRLYLYINDKA-ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIeiydskIKVDGKVLYFGKDIFQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 548 MQDLKeIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQ-DVEQEVQQILSELDM-QNIRDDL---AEHLSEGQKRK 622
Cdd:PRK14246 83 IDAIK-LRKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKrEIKKIVEECLRKVGLwKEVYDRLnspASQLSGGQQQR 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 623 LTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSS 697
Cdd:PRK14246 162 LTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSS 236
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
480-689 |
4.47e-16 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 80.11 E-value: 4.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYKGKSgkvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlkEIRkaig 559
Cdd:PRK11247 15 LNAVSKRYGERT----VLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEARE--DTR---- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 560 vcpqhnVQF-DAL-----TVKENLTLfaKIKGilpqDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDP 633
Cdd:PRK11247 85 ------LMFqDARllpwkKVIDNVGL--GLKG----QWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRP 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 634 QILLLDEPTVGLDPFSR-------QRIW---GFlkerradhVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK11247 153 GLLLLDEPLGALDALTRiemqdliESLWqqhGF--------TVLLVTHDVSEAVAMADRVLLIEEG 210
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
478-688 |
5.52e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 80.52 E-value: 5.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEY-KGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSD--------- 547
Cdd:PRK13651 3 IKVKNIVKIFnKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNkkktkekek 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 548 --------------MQDLKEIRKAIGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDM-QNIRDDL 611
Cdd:PRK13651 83 vleklviqktrfkkIKKIKEIRRRVGVVFQFaEYQLFEQTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLdESYLQRS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 612 AEHLSEGQKRKLTF-GIATVgDPQILLLDEPTVGLDPFSRQRIWGFLKE-------------------RRADHVILFSTQ 671
Cdd:PRK13651 163 PFELSGGQKRRVALaGILAM-EPDFLVFDEPTAGLDPQGVKEILEIFDNlnkqgktiilvthdldnvlEWTKRTIFFKDG 241
|
250 260
....*....|....*....|.
gi 568976233 672 FM----DEADILADRKVLIAN 688
Cdd:PRK13651 242 KIikdgDTYDILSDNKFLIEN 262
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
496-647 |
6.24e-16 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 79.26 E-value: 6.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 496 ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKE 575
Cdd:PRK11300 20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMGVVRTFQHVRLFREMTVIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 576 NLtLFAK--------IKGILP----QDVEQE-VQQILSELDMQNIRD---DLAEHLSEGQKRKLTFGIATVGDPQILLLD 639
Cdd:PRK11300 100 NL-LVAQhqqlktglFSGLLKtpafRRAESEaLDRAATWLERVGLLEhanRQAGNLAYGQQRRLEIARCMVTQPEILMLD 178
|
....*...
gi 568976233 640 EPTVGLDP 647
Cdd:PRK11300 179 EPAAGLNP 186
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
478-689 |
6.51e-16 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 81.61 E-value: 6.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNlsdMQDLKEIRKA 557
Cdd:PRK11000 4 VTLRNVTKAY----GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKR---MNDVPPAERG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:PRK11000 77 VGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 638 LDEPTVGLDPFSR--QRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK11000 157 LDEPLSNLDAALRvqMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAG 210
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
1310-1498 |
9.93e-16 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 77.92 E-value: 9.93e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1310 VNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSsaVGHQGDSRAEFGYCPQENGLWPNLTVKEHLELyAAVK 1389
Cdd:cd03298 21 FAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVD--VTAAPPADRPVSMLFQENNLFAHLTVEQNVGL-GLSP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1390 GLR----KEDAVVAISRLVNALKLHDQLNVQvqnLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAV 1465
Cdd:cd03298 98 GLKltaeDRQAIEVALARVGLAGLEKRLPGE---LSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDL 174
|
170 180 190
....*....|....*....|....*....|...
gi 568976233 1466 VKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:cd03298 175 HAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
1282-1498 |
1.06e-15 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 77.57 E-value: 1.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSsaVGHQGDS-- 1359
Cdd:cd03262 6 LHKSFGDFH-----------VLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLK--LTDDKKNin 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1360 --RAEFGYCPQENGLWPNLTVKEHLELyaA---VKGLRKEDAVVAISRLVNALKLHDQLNVQVQNL-------VAGAtRK 1427
Cdd:cd03262 73 elRQKVGMVFQQFNLFPHLTVLENITL--ApikVKGMSKAEAEERALELLEKVGLADKADAYPAQLsggqqqrVAIA-RA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1428 LCFvlsilgNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:cd03262 150 LAM------NPKVMLFDEPTSALDPELVGEVLDVMKDLAEEG-MTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
478-696 |
1.24e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 79.28 E-value: 1.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSG-KVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYN----KNLSDMQDLK 552
Cdd:PRK13645 7 IILDNVSYTYAKKTPfEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDyaipANLKKIKEVK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 EIRKAIGVCPQH-NVQFDALTVKENLTlFAKIKgiLPQDVEQEVQQILSELDMQNIRDDLAE----HLSEGQKRKLTFGI 627
Cdd:PRK13645 87 RLRKEIGLVFQFpEYQLFQETIEKDIA-FGPVN--LGENKQEAYKKVPELLKLVQLPEDYVKrspfELSGGQKRRVALAG 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 628 ATVGDPQILLLDEPTVGLDPFSRQRIWG-FLK-ERRADHVILFSTQFMDEADILADRKVLIANGALKCTGS 696
Cdd:PRK13645 164 IIAMDGNTLVLDEPTGGLDPKGEEDFINlFERlNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
1302-1479 |
1.27e-15 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 77.45 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDS-----RAEFGYCPQENGLWPNL 1376
Cdd:cd03292 16 ALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVN--GQDVSDLRGRaipylRRKIGVVFQDFRLLPDR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSgkh 1456
Cdd:cd03292 94 NVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPD--- 170
|
170 180
....*....|....*....|....*
gi 568976233 1457 QVWQAIQAVVKDNEKG--VLLSTHD 1479
Cdd:cd03292 171 TTWEIMNLLKKINKAGttVVVATHA 195
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
1305-1499 |
1.35e-15 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 77.78 E-value: 1.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSavGHQGDSR-AEFGYCPQENGLWPNLTV 1378
Cdd:TIGR02211 23 GVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVlfngqSLSKLSS--NERAKLRnKKLGFIYQFHHLLPDFTA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLvAGATRKLCFVLSILGNSPVLIL-DEPSTGLDVSGKHQ 1457
Cdd:TIGR02211 101 LENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSEL-SGGERQRVAIARALVNQPSLVLaDEPTGNLDNNNAKI 179
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1458 VWQAIQAVVKDNEKGVLLSTHDLAEAEALcDRAAIMVSGRLR 1499
Cdd:TIGR02211 180 IFDLMLELNRELNTSFLVVTHDLELAKKL-DRVLEMKDGQLF 220
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
480-661 |
1.62e-15 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 82.08 E-value: 1.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQD--LKEIRKA 557
Cdd:PRK10535 7 LKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDAdaLAQLRRE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 -IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:PRK10535 87 hFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVI 166
|
170 180
....*....|....*....|....*
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERR 661
Cdd:PRK10535 167 LADEPTGALDSHSGEEVMAILHQLR 191
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
478-646 |
2.24e-15 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 77.22 E-value: 2.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGksGKvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ--DLKEIR 555
Cdd:PRK10908 2 IRFEHVSKAYLG--GR-QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKnrEVPFLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQ-HNVQFDAlTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQ 634
Cdd:PRK10908 79 RQIGMIFQdHHLLMDR-TVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPA 157
|
170
....*....|..
gi 568976233 635 ILLLDEPTVGLD 646
Cdd:PRK10908 158 VLLADEPTGNLD 169
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
496-647 |
2.71e-15 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 76.24 E-value: 2.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 496 ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKE-----IRKAIGVCPqhnvqfdA 570
Cdd:TIGR01189 15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHenilyLGHLPGLKP-------E 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 571 LTVKENLTLFAKIKGilpqDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:TIGR01189 88 LSALENLHFWAAIHG----GAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDK 160
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1302-1545 |
3.02e-15 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 81.05 E-value: 3.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE-----LKRLSSAV---GHQGDSR------AEFGYCP 1367
Cdd:PRK10261 31 AVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQcdkmlLRRRSRQVielSEQSAAQmrhvrgADMAMIF 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1368 QE--NGLWPNLTVKEHL-ELYAAVKGLRKEDAVVAISRLVNALKL---HDQLNVQVQNLVAGATRKLCFVLSILGNSPVL 1441
Cdd:PRK10261 111 QEpmTSLNPVFTVGEQIaESIRLHQGASREEAMVEAKRMLDQVRIpeaQTILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLEL-- 1519
Cdd:PRK10261 191 IADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRALla 270
|
250 260
....*....|....*....|....*....
gi 568976233 1520 ---RVKDVSQEPLVHREILKLFPQAARQD 1545
Cdd:PRK10261 271 avpQLGAMKGLDYPRRFPLISLEHPAKQE 299
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
1299-1489 |
3.33e-15 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 80.79 E-value: 3.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNlTV 1378
Cdd:TIGR02857 334 RRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWVPQHPFLFAG-TI 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELY---AAVKGLRKEDAVVAISRLVNALK--LHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVS 1453
Cdd:TIGR02857 413 AENIRLArpdASDAEIREALERAGLDEFVAALPqgLDTPIGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAE 492
|
170 180 190
....*....|....*....|....*....|....*.
gi 568976233 1454 GKHQVWQAIQAVVKDneKGVLLSTHDLAEAEaLCDR 1489
Cdd:TIGR02857 493 TEAEVLEALRALAQG--RTVLLVTHRLALAA-LADR 525
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
474-696 |
3.98e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 78.35 E-value: 3.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIKKEYKGK-SGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTV---YNKNLSD-- 547
Cdd:PRK13631 18 DDIILRVKNLYCVFDEKqENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiYIGDKKNnh 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 548 ----------MQDLKEIRKAIGVCPQH-NVQFDALTVKENLtLFAKIKgiLPQDVEQEVQQILSELDMQNIRDDLAEH-- 614
Cdd:PRK13631 98 elitnpyskkIKNFKELRRRVSMVFQFpEYQLFKDTIEKDI-MFGPVA--LGVKKSEAKKLAKFYLNKMGLDDSYLERsp 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 615 --LSEGQKRKLTF-GIATVgDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFS-TQFMDEADILADRKVLIANGA 690
Cdd:PRK13631 175 fgLSGGQKRRVAIaGILAI-QPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFViTHTMEHVLEVADEVIVMDKGK 253
|
....*.
gi 568976233 691 LKCTGS 696
Cdd:PRK13631 254 ILKTGT 259
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
1303-1498 |
4.06e-15 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 74.95 E-value: 4.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNlTVKEhl 1382
Cdd:cd03246 18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGYLPQDDELFSG-SIAE-- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 elyaavkglrkedavvaisrlvnalklhdqlnvqvqNLVAGATR-KLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQA 1461
Cdd:cd03246 95 ------------------------------------NILSGGQRqRLGLARALYGNPRILVLDEPNSHLDVEGERALNQA 138
|
170 180 190
....*....|....*....|....*....|....*..
gi 568976233 1462 IQAvVKDNEKGVLLSTHDLaEAEALCDRAAIMVSGRL 1498
Cdd:cd03246 139 IAA-LKAAGATRIVIAHRP-ETLASADRILVLEDGRV 173
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
1302-1498 |
4.52e-15 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 76.59 E-value: 4.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--------KRLSSAVGHQgdSRAEFGYCPQENGLW 1373
Cdd:COG4161 17 ALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIaghqfdfsQKPSEKAIRL--LRQKVGMVFQQYNLW 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVKEHL-ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:COG4161 95 PHLTVMENLiEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDP 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568976233 1453 SGKHQVWQAIQAVvkdNEKGV--LLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:COG4161 175 EITAQVVEIIREL---SQTGItqVIVTHEVEFARKVASQVVYMEKGRI 219
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
1302-1483 |
4.57e-15 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 75.15 E-value: 4.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQG--DSRAEFGYC---PQENGLWPnl 1376
Cdd:TIGR01166 7 VLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDYSRKGllERRQRVGLVfqdPDDQLFAA-- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLrKEDAVVAisRLVNALKLHDQLNVQVQ--NLVAGATRKLCFVLSILGNSP-VLILDEPSTGLDVS 1453
Cdd:TIGR01166 85 DVDQDVAFGPLNLGL-SEAEVER--RVREALTAVGASGLRERptHCLSGGEKKRVAIAGAVAMRPdVLLLDEPTAGLDPA 161
|
170 180 190
....*....|....*....|....*....|
gi 568976233 1454 GKHQVWQAIQAVVkDNEKGVLLSTHDLAEA 1483
Cdd:TIGR01166 162 GREQMLAILRRLR-AEGMTVVISTHDVDLA 190
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
1303-1504 |
5.27e-15 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 75.97 E-value: 5.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDSR-AEFgycpQENGLWPNLTVKEH 1381
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILE--GKQITEPGPDRmVVF----QNYSLLPWLTVREN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELyaAVKGLR-------KEDAVVAISRLVN----ALKLHDQLNVQVQNLVAGATrklcfVLSIlgNSPVLILDEPSTGL 1450
Cdd:TIGR01184 75 IAL--AVDRVLpdlskseRRAIVEEHIALVGlteaADKRPGQLSGGMKQRVAIAR-----ALSI--RPKVLLLDEPFGAL 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1451 DVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPI 1504
Cdd:TIGR01184 146 DALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQI 199
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
473-689 |
5.36e-15 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 78.84 E-value: 5.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 473 QGKEAIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsDMQDLK 552
Cdd:PRK09452 10 SLSPLVELRGISKSFDGK----EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQ---DITHVP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 EIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGD 632
Cdd:PRK09452 83 AENRHVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNK 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 633 PQILLLDEPTVGLDPFSRQRIWGFLK--ERRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK09452 163 PKVLLLDESLSALDYKLRKQMQNELKalQRKLGITFVFVTHDQEEALTMSDRIVVMRDG 221
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
495-653 |
5.40e-15 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 80.55 E-value: 5.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 495 KALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFDAlTVK 574
Cdd:TIGR01193 488 NILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDI-DRHTLRQFINYLPQEPYIFSG-SIL 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 575 ENLTLFAKikgilpQDVEQEvqQILSELDMQNIRDD-----------LAEH---LSEGQKRKLTFGIATVGDPQILLLDE 640
Cdd:TIGR01193 566 ENLLLGAK------ENVSQD--EIWAACEIAEIKDDienmplgyqteLSEEgssISGGQKQRIALARALLTDSKVLILDE 637
|
170
....*....|...
gi 568976233 641 PTVGLDPFSRQRI 653
Cdd:TIGR01193 638 STSNLDTITEKKI 650
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1291-1514 |
5.91e-15 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 76.28 E-value: 5.91e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1291 KHCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV--------------ELKR----LSSA 1352
Cdd:COG1119 7 RNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDvrlfgerrggedvwELRKriglVSPA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1353 VGHQgdsraefgYCPQEN-------------GLWPNLTvkehlelyaavkglrKEDAVVAIsRLVNALKLHDQLNVQVQN 1419
Cdd:COG1119 87 LQLR--------FPRDETvldvvlsgffdsiGLYREPT---------------DEQRERAR-ELLELLGLAHLADRPFGT 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1420 LVAGATRKlcfVL---SILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSG 1496
Cdd:COG1119 143 LSQGEQRR---VLiarALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDG 219
|
250 260
....*....|....*....|....
gi 568976233 1497 RLRCIGPI------QHLKRKFGQD 1514
Cdd:COG1119 220 RVVAAGPKeevltsENLSEAFGLP 243
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
478-691 |
7.37e-15 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 75.59 E-value: 7.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSgKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlKEIRKA 557
Cdd:cd03248 12 VKFQNVTFAYPTRP-DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEH-KYLHSK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFdALTVKENLtlfAKIKGILPQDVEQEVQQ------ILSELDmQNIRDDLAE---HLSEGQKRKLTFGIA 628
Cdd:cd03248 90 VSLVGQEPVLF-ARSLQDNI---AYGLQSCSFECVKEAAQkahahsFISELA-SGYDTEVGEkgsQLSGGQKQRVAIARA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 629 TVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADiLADRKVLIANGAL 691
Cdd:cd03248 165 LIRNPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVE-RADQILVLDGGRI 226
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
497-664 |
8.42e-15 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 75.59 E-value: 8.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLK--EIR-KAIGVCPQHNVQFDALTV 573
Cdd:PRK10584 26 LTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEAraKLRaKHVGFVFQSFMLIPTLNA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 574 KENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:PRK10584 106 LENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKI 185
|
170
....*....|.
gi 568976233 654 WGFLKERRADH 664
Cdd:PRK10584 186 ADLLFSLNREH 196
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1303-1498 |
9.57e-15 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 78.89 E-value: 9.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrlssavghqgDSRAEFGYCPQE------------- 1369
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTL-----------DGHEVVTRSPQDglangivyisedr 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1370 --NGLWPNLTVKEHLELYA------AVKGLRKEDAVVAISRLVNALKLH----DQlnvQVQNLVAGATRKLCFVLSILGN 1437
Cdd:PRK10762 337 krDGLVLGMSVKENMSLTAlryfsrAGGSLKHADEQQAVSDFIRLFNIKtpsmEQ---AIGLLSGGNQQKVAIARGLMTR 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1438 SPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSThDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK10762 414 PKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSS-EMPEVLGMSDRILVMHEGRI 473
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1302-1539 |
9.63e-15 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 79.06 E-value: 9.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLS-SAVGHQGDSRAEFGYCPQENGLWPNLTVKE 1380
Cdd:PRK09700 20 ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINyNKLDHKLAAQLGIGIIYQELSVIDELTVLE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HL----ELYAAVKGLR----KEDAVVAiSRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:PRK09700 100 NLyigrHLTKKVCGVNiidwREMRVRA-AMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTN 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1453 SGKHQVWqAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGpiqhlkrkfgqdyvlelRVKDVSQEPLVH- 1531
Cdd:PRK09700 179 KEVDYLF-LIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG-----------------MVSDVSNDDIVRl 240
|
250
....*....|.
gi 568976233 1532 ---REILKLFP 1539
Cdd:PRK09700 241 mvgRELQNRFN 251
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
497-653 |
1.27e-14 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 74.45 E-value: 1.27e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlkEIRKAIGVCPQHNVQFDALTVKEN 576
Cdd:cd03231 16 FSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRD--SIARGLLYLGHAPGIKTTLSVLEN 93
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 577 LTLFAKIKGilpqdvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:cd03231 94 LRFWHADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARF 164
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
508-696 |
1.69e-14 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 78.73 E-value: 1.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 508 QITAILGHSGAGKSSLLNILSGlYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQhNVQFDALTVKENLTLfAKikgil 587
Cdd:PRK11174 377 QRIALVGPSGAGKTSLLNALLG-FLPYQGSLKINGIELREL-DPESWRKHLSWVGQ-NPQLPHGTLRDNVLL-GN----- 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 588 PQDVEQEVQQILSELDMQNIRDDLAE-----------HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGF 656
Cdd:PRK11174 448 PDASDEQLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQA 527
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 657 LKERRADHVILFSTQFMDEadiLA--DRKVLIANGALKCTGS 696
Cdd:PRK11174 528 LNAASRRQTTLMVTHQLED---LAqwDQIWVMQDGQIVQQGD 566
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
1296-1498 |
1.72e-14 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 75.61 E-value: 1.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1296 RRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV--------ELKRlSSAVGHQGDSRAEFGYCP 1367
Cdd:TIGR02769 20 AKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVsfrgqdlyQLDR-KQRRAFRRDVQLVFQDSP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1368 qeNGLWPNLTVK-------EHLELYAAVKGLRKedavvaISRLVNALKLHDQ-LNVQVQNLVAGATRKLCFVLSILGNSP 1439
Cdd:TIGR02769 99 --SAVNPRMTVRqiigeplRHLTSLDESEQKAR------IAELLDMVGLRSEdADKLPRQLSGGQLQRINIARALAVKPK 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1440 VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:TIGR02769 171 LIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQI 229
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
478-691 |
1.85e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 75.51 E-value: 1.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKgKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdMQDLKEIRKA 557
Cdd:PRK13642 5 LEVENLVFKYE-KESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLT-AENVWNLRRK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQH-NVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQIL 636
Cdd:PRK13642 83 IGMVFQNpDNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEII 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQFMDEAdILADRKVLIANGAL 691
Cdd:PRK13642 163 ILDESTSMLDPTGRQEIMRVIHEIKEKYqlTVLSITHDLDEA-ASSDRILVMKAGEI 218
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
480-646 |
2.11e-14 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 78.18 E-value: 2.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVyNKNLSdmqdlkeirkaIG 559
Cdd:COG0488 1 LENLSKSF----GGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI-PKGLR-----------IG 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 560 VCPQHNVQFDALTVKEN-LTLFAKIKGILPQ-------------------------------DVEQEVQQILSELDM-QN 606
Cdd:COG0488 65 YLPQEPPLDDDLTVLDTvLDGDAELRALEAEleeleaklaepdedlerlaelqeefealggwEAEARAEEILSGLGFpEE 144
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 568976233 607 IRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:COG0488 145 DLDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLD 184
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1282-1516 |
2.28e-14 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 74.74 E-value: 2.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGdsrA 1361
Cdd:PRK11248 7 LYADYGGKP-----------ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLD--GKPVEGPG---A 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1362 EFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVL 1441
Cdd:PRK11248 71 ERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCigpIQHLKRKFGQDYV 1516
Cdd:PRK11248 151 LLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRV---VERLPLNFARRFV 222
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
478-686 |
2.64e-14 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 74.44 E-value: 2.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdMQDLKEIRKA 557
Cdd:cd03252 1 ITFEHVRFRYKPDGPVI--LDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLA-LADPAWLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLTLfakikgilpQDVEQEVQQILSELDMQNIRDDLAE--------------HLSEGQKRKL 623
Cdd:cd03252 78 VGVVLQENVLFNR-SIRDNIAL---------ADPGMSMERVIEAAKLAGAHDFISElpegydtivgeqgaGLSGGQRQRI 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 624 TFGIATVGDPQILLLDEPTVGLDPFSrqriwgflkerraDHVILFSTQfmdeaDILADRKVLI 686
Cdd:cd03252 148 AIARALIHNPRILIFDEATSALDYES-------------EHAIMRNMH-----DICAGRTVII 192
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
481-692 |
2.73e-14 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 74.08 E-value: 2.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 481 RNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLK--EIR-KA 557
Cdd:PRK11629 9 DNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAkaELRnQK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:PRK11629 89 LGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVL 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILaDRKVLIANGALK 692
Cdd:PRK11629 169 ADEPTGNLDARNADSIFQLLGElnRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRLT 224
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1274-1489 |
3.29e-14 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 77.41 E-value: 3.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1274 KPVIIASCLHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrlssav 1353
Cdd:COG0488 313 KKVLELEGLSKSYGDKT-----------LLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL------- 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1354 GHqgdsRAEFGYCPQEN-GLWPNLTVKEHLelyaavKGLRKEDAVVAISRLVNALKLH-DQLNVQVQNLVAGATRKLCFV 1431
Cdd:COG0488 375 GE----TVKIGYFDQHQeELDPDKTVLDEL------RDGAPGGTEQEVRGYLGRFLFSgDDAFKPVGVLSGGEKARLALA 444
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1432 LSILGNSPVLILDEPSTGLDVsgkhqvwQAIQAVVK--DNEKG-VLLSTHDLAEAEALCDR 1489
Cdd:COG0488 445 KLLLSPPNVLLLDEPTNHLDI-------ETLEALEEalDDFPGtVLLVSHDRYFLDRVATR 498
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1310-1494 |
3.68e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 77.52 E-value: 3.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1310 VNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-RLSsavghqgdsraefgYCPQENGLWPNLTVKEHleLYAAV 1388
Cdd:COG1245 363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDlKIS--------------YKPQYISPDYDGTVEEF--LRSAN 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1389 KglRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKD 1468
Cdd:COG1245 427 T--DDFGSSYYKTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAEN 504
|
170 180
....*....|....*....|....*.
gi 568976233 1469 NEKGVLLSTHDLAEAEALCDRaaIMV 1494
Cdd:COG1245 505 RGKTAMVVDHDIYLIDYISDR--LMV 528
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
1303-1507 |
4.13e-14 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 73.97 E-value: 4.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKP----TAGQV----------ELKRLSSAVGHQgDSRAEFGycpq 1368
Cdd:PRK10418 19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVlldgkpvapcALRGRKIATIMQ-NPRSAFN---- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1369 englwPNLTVKEH-LELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPS 1447
Cdd:PRK10418 94 -----PLHTMHTHaRETCLALGKPADDATLTAALEAVGLENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPT 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1448 TGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:PRK10418 169 TDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETL 228
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
1299-1480 |
4.50e-14 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 73.81 E-value: 4.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRN----VSFCVNKGEILGLLGPDGAGKSSSIRMIAGITkPTAGQVEL--KRLSSAVGH-QGDSRAefgYCPQENG 1371
Cdd:PRK03695 4 NDVAVSTrlgpLSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFagQPLEAWSAAeLARHRA---YLSQQQT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNLTVKEHLELYAAVkGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSP-------VLILD 1444
Cdd:PRK03695 80 PPFAMPVFQYLTLHQPD-KTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQVWPdinpagqLLLLD 158
|
170 180 190
....*....|....*....|....*....|....*...
gi 568976233 1445 EPSTGLDVSGKHQVWQAIQAVVkdnEKG--VLLSTHDL 1480
Cdd:PRK03695 159 EPMNSLDVAQQAALDRLLSELC---QQGiaVVMSSHDL 193
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
473-647 |
4.79e-14 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 74.07 E-value: 4.79e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 473 QGKEAIRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNL------- 545
Cdd:COG4598 4 TAPPALEVRDLHKSF----GDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrlkpdrd 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 546 -----SDMQDLKEIRKAIGVCPQHnvqFDA---LTVKENLTlFAKI--KGILPQDVEQEVQQILSELDMQNIRDDLAEHL 615
Cdd:COG4598 80 gelvpADRRQLQRIRTRLGMVFQS---FNLwshMTVLENVI-EAPVhvLGRPKAEAIERAEALLAKVGLADKRDAYPAHL 155
|
170 180 190
....*....|....*....|....*....|..
gi 568976233 616 SEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:COG4598 156 SGGQQQRAAIARALAMEPEVMLFDEPTSALDP 187
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1303-1498 |
4.85e-14 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 73.31 E-value: 4.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAVGHQGDSRaEFGYCPQENGLWPNLT 1377
Cdd:PRK11629 25 LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVifngqPMSKLSSAAKAELRNQ-KLGFIYQFHHLLPDFT 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1378 VKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLvAGATRKLCFVLSILGNSPVLIL-DEPSTGLDVSGKH 1456
Cdd:PRK11629 104 ALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSEL-SGGERQRVAIARALVNNPRLVLaDEPTGNLDARNAD 182
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1457 QVWQAIQAVVKDNEKGVLLSTHDLAEAEALcDRAAIMVSGRL 1498
Cdd:PRK11629 183 SIFQLLGELNRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRL 223
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
486-647 |
5.04e-14 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 73.85 E-value: 5.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 486 EYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS------------DMQDLKE 553
Cdd:PRK10619 10 DLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgqlkvaDKNQLRL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 IRKAIGVCPQHNVQFDALTVKEN-LTLFAKIKGILPQDVEQEVQQILSELDM-QNIRDDLAEHLSEGQKRKLTFGIATVG 631
Cdd:PRK10619 90 LRTRLTMVFQHFNLWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIdERAQGKYPVHLSGGQQQRVSIARALAM 169
|
170
....*....|....*.
gi 568976233 632 DPQILLLDEPTVGLDP 647
Cdd:PRK10619 170 EPEVLLFDEPTSALDP 185
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
478-729 |
5.77e-14 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 73.20 E-value: 5.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ-DLKEIRK 556
Cdd:PRK09493 2 IEFKNVSKHF----GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKvDERLIRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLtLFA--KIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQ 634
Cdd:PRK09493 78 EAGMVFQQFYLFPHLTALENV-MFGplRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 635 ILLLDEPTVGLDPFSRQ---RIWGFLKERRADHVILfsTQFMDEADILADRKVLIANGALKCTGSSVFLkrkwglgyhls 711
Cdd:PRK09493 157 LMLFDEPTSALDPELRHevlKVMQDLAEEGMTMVIV--THEIGFAEKVASRLIFIDKGRIAEDGDPQVL----------- 223
|
250
....*....|....*...
gi 568976233 712 lfMDETCdSERLTSFINH 729
Cdd:PRK09493 224 --IKNPP-SQRLQEFLQH 238
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
1302-1513 |
7.13e-14 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 76.47 E-value: 7.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSS--AVGhqgdsraefgycpqeNGLWPNLTVK 1379
Cdd:PRK13545 39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAAliAIS---------------SGLNGQLTGI 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 EHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVW 1459
Cdd:PRK13545 104 ENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCL 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1460 QAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQ 1513
Cdd:PRK13545 184 DKMNE-FKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYDE 236
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
474-691 |
8.39e-14 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 76.22 E-value: 8.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIkkEYKGKSGkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS-----DM 548
Cdd:COG3845 254 GEVVLEVENL--SVRDDRG-VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITglsprER 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 549 QDLK-----EIRKAIGVCPqhnvqfdALTVKENLTL-------FAKiKGIL-PQDVEQEVQQILSELDmqnIR----DDL 611
Cdd:COG3845 331 RRLGvayipEDRLGRGLVP-------DMSVAENLILgryrrppFSR-GGFLdRKAIRAFAEELIEEFD---VRtpgpDTP 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 612 AEHLSEG--QK----RKLTfgiatvGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH--VILFSTQfMDEADILADRK 683
Cdd:COG3845 400 ARSLSGGnqQKvilaRELS------RDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGaaVLLISED-LDEILALSDRI 472
|
....*...
gi 568976233 684 VLIANGAL 691
Cdd:COG3845 473 AVMYEGRI 480
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
476-690 |
1.31e-13 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 72.08 E-value: 1.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 476 EAIRIRNIKKEYK-----GKsgKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKN-LSDM- 548
Cdd:COG4778 3 TLLEVENLSKTFTlhlqgGK--RLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGgWVDLa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 549 ----QDLKEIRK-AIGVCPQH-NV--QFDAL-TVKENLTLfakiKGILPQDVEQEVQQILSELdmqnirdDLAEHL---- 615
Cdd:COG4778 81 qaspREILALRRrTIGYVSQFlRVipRVSALdVVAEPLLE----RGVDREEARARARELLARL-------NLPERLwdlp 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 616 ----SEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTqFMDEA--DILADRKVLIANG 689
Cdd:COG4778 150 patfSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGI-FHDEEvrEAVADRVVDVTPF 228
|
.
gi 568976233 690 A 690
Cdd:COG4778 229 S 229
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1310-1494 |
1.44e-13 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 75.62 E-value: 1.44e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1310 VNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-RLSsavghqgdsraefgYCPQENGLWPNLTVKEHLElyaav 1388
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPElKIS--------------YKPQYIKPDYDGTVEDLLR----- 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1389 KGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKD 1468
Cdd:PRK13409 423 SITDDLGSSYYKSEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEE 502
|
170 180
....*....|....*....|....*.
gi 568976233 1469 NEKGVLLSTHDLAEAEALCDRaaIMV 1494
Cdd:PRK13409 503 REATALVVDHDIYMIDYISDR--LMV 526
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1304-1498 |
2.09e-13 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 74.70 E-value: 2.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAvghqgdSRAEFG--YCP---QENGLw 1373
Cdd:PRK15439 280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRImlngkEINALSTA------QRLARGlvYLPedrQSSGL- 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 pnltvkeHLE--LYAAVKGL-----------RKEDAVVAISRLVNALKLHDqLNVQVQNLVAGATRKLCFVLSILGNSPV 1440
Cdd:PRK15439 353 -------YLDapLAWNVCALthnrrgfwikpARENAVLERYRRALNIKFNH-AEQAARTLSGGNQQKVLIAKCLEASPQL 424
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1441 LILDEPSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK15439 425 LIVDEPTRGVDVSARNDIYQLIRSIAAQN-VAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
493-651 |
2.48e-13 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 75.14 E-value: 2.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 493 KVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFdALT 572
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQY-DHHYLHRQVALVGQEPVLF-SGS 570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 573 VKENLTL---FAKIKGILPQDVEQEVQQILSELDmQNIRDDLAEH---LSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:TIGR00958 571 VRENIAYgltDTPDEEIMAAAKAANAHDFIMEFP-NGYDTEVGEKgsqLSGGQKQRIAIARALVRKPRVLILDEATSALD 649
|
....*
gi 568976233 647 PFSRQ 651
Cdd:TIGR00958 650 AECEQ 654
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
1293-1507 |
3.30e-13 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 74.70 E-value: 3.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1293 CCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPtagqvELKRLSSAV--GHQGDS---RAEFGYCP 1367
Cdd:TIGR00955 31 FCRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPK-----GVKGSGSVLlnGMPIDAkemRAISAYVQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1368 QENGLWPNLTVKEHLELYAAVK---GLRKEDAVVAISRLVNALKLHDQLNV------QVQNLVAGATRKLCFVLSILGNS 1438
Cdd:TIGR00955 106 QDDLFIPTLTVREHLMFQAHLRmprRVTKKEKRERVDEVLQALGLRKCANTrigvpgRVKGLSGGERKRLAFASELLTDP 185
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1439 PVLILDEPSTGLDVSGKHQVWQAIQAVVkDNEKGVLLSTHD-LAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:TIGR00955 186 PLLFCDEPTSGLDSFMAYSVVQVLKGLA-QKGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPDQA 254
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
1302-1514 |
3.70e-13 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 74.78 E-value: 3.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL-------KRLSSAVGHQgdsraeFGYCPQENG--L 1372
Cdd:NF033858 16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVlggdmadARHRRAVCPR------IAYMPQGLGknL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1373 WPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRK--LCFVLsIlgNSP-VLILDEPSTG 1449
Cdd:NF033858 90 YPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKlgLCCAL-I--HDPdLLILDEPTTG 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1450 LDVSGKHQVWQAIQAVVKDNEK-GVLLSTHDLAEAEAlCDRAAIMVSGRLRCIGPIQHLKRKFGQD 1514
Cdd:NF033858 167 VDPLSRRQFWELIDRIRAERPGmSVLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTGAD 231
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
1300-1526 |
3.83e-13 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 73.14 E-value: 3.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQ-----VELKRLSSAVGHQgDSRAEFGYCPQENGLWP 1374
Cdd:PRK10070 41 SLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQvlidgVDIAKISDAELRE-VRRKKIAMVFQSFALMP 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKEH----LELYAAVKGLRKEDAVVAISRlvnaLKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGL 1450
Cdd:PRK10070 120 HMTVLDNtafgMELAGINAEERREKALDALRQ----VGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSAL 195
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1451 DVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLE-LRVKDVSQ 1526
Cdd:PRK10070 196 DPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTfFRGVDISQ 272
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1301-1497 |
4.16e-13 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 71.17 E-value: 4.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1301 MAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQ----GDSRAeFgycpQENGLWP 1374
Cdd:PRK11300 19 LAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLrgQHIEGLPGHQiarmGVVRT-F----QHVRLFR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKE------HLELYAAV-KGL-------RKEDAvvAISRLVNALK---LHDQLNVQVQNLVAGATRKLCFVLSILGN 1437
Cdd:PRK11300 94 EMTVIEnllvaqHQQLKTGLfSGLlktpafrRAESE--ALDRAATWLErvgLLEHANRQAGNLAYGQQRRLEIARCMVTQ 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1438 SPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK11300 172 PEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGT 231
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1307-1507 |
5.33e-13 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 70.38 E-value: 5.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1307 SFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlssAVGHQGDSRAE------FgycpQENGLWPNLTVKE 1380
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLN----GQDHTTTPPSRrpvsmlF----QENNLFSHLTVAQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HLELYAAvKGLR----KEDAVVAISRLVNALKLHDQLNVQV---QNLVAGATRklCFVLSilgnSPVLILDEPSTGLDVS 1453
Cdd:PRK10771 91 NIGLGLN-PGLKlnaaQREKLHAIARQMGIEDLLARLPGQLsggQRQRVALAR--CLVRE----QPILLLDEPFSALDPA 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1454 GKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:PRK10771 164 LRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
478-697 |
6.31e-13 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 73.30 E-value: 6.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL--YVPTAGSVtVYNKNLSDMQDLKEIR 555
Cdd:TIGR03269 1 IEVKNLTKKFDGK----EVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRI-IYHVALCEKCGYVERP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIG----VCPQHNVQFDALTVKENLTLFAKIK---GILPQ------------------------DVEQEVQQILSELDM 604
Cdd:TIGR03269 76 SKVGepcpVCGGTLEPEEVDFWNLSDKLRRRIRkriAIMLQrtfalygddtvldnvlealeeigyEGKEAVGRAVDLIEM 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 605 QNIRD---DLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADIL 679
Cdd:TIGR03269 156 VQLSHritHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEavKASGISMVLTSHWPEVIEDL 235
|
250
....*....|....*...
gi 568976233 680 ADRKVLIANGALKCTGSS 697
Cdd:TIGR03269 236 SDKAIWLENGEIKEEGTP 253
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
1302-1468 |
6.75e-13 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 69.95 E-value: 6.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlssavGHQ------GDSRAEFGYCPQENGLWpN 1375
Cdd:cd03251 17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILID------GHDvrdytlASLRRQIGLVSQDVFLF-N 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 LTVKEHLeLYAAVKGLRKEdaVVAISRLVNAL----KLHDQLNVQVQ----NLVAGATRKLCFVLSILGNSPVLILDEPS 1447
Cdd:cd03251 90 DTVAENI-AYGRPGATREE--VEEAARAANAHefimELPEGYDTVIGergvKLSGGQRQRIAIARALLKDPPILILDEAT 166
|
170 180
....*....|....*....|.
gi 568976233 1448 TGLDVSGKHQVWQAIQAVVKD 1468
Cdd:cd03251 167 SALDTESERLVQAALERLMKN 187
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
1302-1498 |
8.25e-13 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 69.70 E-value: 8.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKP----TAGQVELK-RLSSAVGHQGDsraEFGYCPQE--NGLWP 1374
Cdd:TIGR02770 1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPgltqTSGEILLDgRPLLPLSIRGR---HIATIMQNprTAFNP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQ---LNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLD 1451
Cdd:TIGR02770 78 LFTMGNHAIETLRSLGKLSKQARALILEALEAVGLPDPeevLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLD 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 568976233 1452 VSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:TIGR02770 158 VVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRI 204
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
499-646 |
8.42e-13 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 69.06 E-value: 8.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 499 GLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM-----QDLKEIRKAIGVcpqhnvqFDALTV 573
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQrdeyhQDLLYLGHQPGI-------KTELTA 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 574 KENLTLFAKIKGilPQDvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PRK13538 92 LENLRFYQRLHG--PGD-DEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1302-1498 |
9.31e-13 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 70.49 E-value: 9.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDS----RAEFGYC---PQENGLWP 1374
Cdd:PRK13639 17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIK--GEPIKYDKKSllevRKTVGIVfqnPDDQLFAP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 nlTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLvAGATRKLCFVLSILGNSP-VLILDEPSTGLDVS 1453
Cdd:PRK13639 95 --TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHL-SGGQKKRVAIAGILAMKPeIIVLDEPTSGLDPM 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 568976233 1454 GKHQVWQAIQAVvkdNEKG--VLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK13639 172 GASQIMKLLYDL---NKEGitIIISTHDVDLVPVYADKVYVMSDGKI 215
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
1308-1478 |
9.53e-13 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 69.11 E-value: 9.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1308 FCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPqenGLWPNLTVKEHLELYAA 1387
Cdd:PRK13543 32 FHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFMAYLGHLP---GLKADLSTLENLHFLCG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1388 VKGLRKEDAVVAISRLVNalkLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVK 1467
Cdd:PRK13543 109 LHGRRAKQMPGSALAIVG---LAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHLR 185
|
170
....*....|.
gi 568976233 1468 dNEKGVLLSTH 1478
Cdd:PRK13543 186 -GGGAALVTTH 195
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
1302-1517 |
1.06e-12 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 69.44 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWpNLTVKEH 1381
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVVLQENVLF-NRSIRDN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKedaVVAISRLVNA----LKLHDQLNVQV----QNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVS 1453
Cdd:cd03252 96 IALADPGMSMER---VIEAAKLAGAhdfiSELPEGYDTIVgeqgAGLSGGQRQRIAIARALIHNPRILIFDEATSALDYE 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1454 GKHQVWQAIQAVVKDneKGVLLSTHDLAEAEAlCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVL 1517
Cdd:cd03252 173 SEHAIMRNMHDICAG--RTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAENGLYAYL 233
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1303-1498 |
1.27e-12 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 69.66 E-value: 1.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGD---SRAeFGYCPQENGLWPNLTVK 1379
Cdd:PRK11231 18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLG--DKPISMLSSrqlARR-LALLPQHHLTPEGITVR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1380 E--------HLELYAAVKGLRKEDAVVAISRLvNALKLHDQLnvqVQNLvAGATRKLCFVLSILG-NSPVLILDEPSTGL 1450
Cdd:PRK11231 95 ElvaygrspWLSLWGRLSAEDNARVNQAMEQT-RINHLADRR---LTDL-SGGQRQRAFLAMVLAqDTPVVLLDEPTTYL 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 568976233 1451 DVSgkHQV-WQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK11231 170 DIN--HQVeLMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHV 216
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1304-1479 |
1.43e-12 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 72.02 E-value: 1.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrlssavghqgDSRAEFGYCPQENGLWPNLTVKE--- 1380
Cdd:COG0488 15 DDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI-----------PKGLRIGYLPQEPPLDDDLTVLDtvl 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 --HLELYAAVKGLRKEDAVVA---------------------------ISRLVNALKLH-DQLNVQVQNLvAGATRK--- 1427
Cdd:COG0488 84 dgDAELRALEAELEELEAKLAepdedlerlaelqeefealggweaearAEEILSGLGFPeEDLDRPVSEL-SGGWRRrva 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1428 LCFVLsiLGNSPVLILDEPSTGLDVsgkhqvwQAIQ---AVVKDNEKGVLLSTHD 1479
Cdd:COG0488 163 LARAL--LSEPDLLLLDEPTNHLDL-------ESIEwleEFLKNYPGTVLVVSHD 208
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
1300-1451 |
1.48e-12 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 69.27 E-value: 1.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKR----LSSAVGHQG--DSRAEFGYCPQENGLW 1373
Cdd:PRK11124 15 HQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhfdFSKTPSDKAirELRRNVGMVFQQYNLW 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1374 PNLTVKEHL-ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLD 1451
Cdd:PRK11124 95 PHLTVQQNLiEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALD 173
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
1291-1510 |
2.02e-12 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 70.52 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1291 KHCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDSRAEFGYCPQEN 1370
Cdd:PRK11432 10 KNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFID--GEDVTHRSIQQRDICMVFQSY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1371 GLWPNLTVKEHLELYAAVKGLRKEDAVvaiSRLVNALKL----------HDQLNVQVQNLVAGAtRKLcfvlsILgNSPV 1440
Cdd:PRK11432 88 ALFPHMSLGENVGYGLKMLGVPKEERK---QRVKEALELvdlagfedryVDQISGGQQQRVALA-RAL-----IL-KPKV 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1441 LILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRK 1510
Cdd:PRK11432 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQ 227
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
1266-1503 |
2.02e-12 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 70.75 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1266 LSTPNLDEKPVIIASCLHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE 1345
Cdd:PRK09452 4 LNKQPSSLSPLVELRGISKSFDGKE-----------VISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1346 L--KRLSSAVGHQGDSRAEFgycpQENGLWPNLTVKEHLELyaavkGLR--KEDAVVAISRLVNALK---LHDQLNVQVQ 1418
Cdd:PRK09452 73 LdgQDITHVPAENRHVNTVF----QSYALFPHMTVFENVAF-----GLRmqKTPAAEITPRVMEALRmvqLEEFAQRKPH 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1419 NLVAGATRKLCFVLSILGNSPVLILDEPSTGLDvsgkHQVWQAIQAVVKDNEK--GV--LLSTHDLAEAEALCDRAAIMV 1494
Cdd:PRK09452 144 QLSGGQQQRVAIARAVVNKPKVLLLDESLSALD----YKLRKQMQNELKALQRklGItfVFVTHDQEEALTMSDRIVVMR 219
|
....*....
gi 568976233 1495 SGRLRCIGP 1503
Cdd:PRK09452 220 DGRIEQDGT 228
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
1302-1507 |
2.24e-12 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 68.36 E-value: 2.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGI-----TKPTAGQVELKrlSSAVGHQGDS----RAEFGYCPQEngl 1372
Cdd:cd03260 15 ALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLD--GKDIYDLDVDvlelRRRVGMVFQK--- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1373 wPNL---TVKEHLELYAAVKGLRKEDAVVAISRlvNALK---LHDQLNvqvQNLVA-----GATRKLCFVLSILGNSPVL 1441
Cdd:cd03260 90 -PNPfpgSIYDNVAYGLRLHGIKLKEELDERVE--EALRkaaLWDEVK---DRLHAlglsgGQQQRLCLARALANEPEVL 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAVvkDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:cd03260 164 LLDEPTSALDPISTAKIEELIAEL--KKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1293-1517 |
2.62e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 69.06 E-value: 2.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1293 CCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-------------ELKRLSSAVGHQGDS 1359
Cdd:PRK13652 10 CYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVlirgepitkenirEVRKFVGLVFQNPDD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1360 RAefgYCPqenglwpnlTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDqLNVQVQNLVAGATRKLCFVLSILGNSP 1439
Cdd:PRK13652 90 QI---FSP---------TVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEE-LRDRVPHHLSGGEKKRVAIAGVIAMEP 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1440 -VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLkrkFGQDYVL 1517
Cdd:PRK13652 157 qVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEI---FLQPDLL 232
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
497-664 |
3.41e-12 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 71.39 E-value: 3.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsDMQDLKEI-----RKAIGVCPQHNVQFdal 571
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILI------DGQDIRDVtqaslRAAIGIVPQDTVLF--- 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 572 tvkeNLTLFAKIKGILPQDVEQEVQQIlseLDMQNIrDDLAEHLSEGQK-----R--KLTFG------IATV--GDPQIL 636
Cdd:COG5265 445 ----NDTIAYNIAYGRPDASEEEVEAA---ARAAQI-HDFIESLPDGYDtrvgeRglKLSGGekqrvaIARTllKNPPIL 516
|
170 180
....*....|....*....|....*...
gi 568976233 637 LLDEPTVGLDPFSRQRIWGFLKERRADH 664
Cdd:COG5265 517 IFDEATSALDSRTERAIQAALREVARGR 544
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
480-695 |
3.57e-12 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 68.17 E-value: 3.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL--YVPTAGSVTVYNKNLSDMqdlkEI--- 554
Cdd:COG0396 3 IKNLHVSVEGK----EILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGEDILEL----SPder 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 -RKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQ---EVQQILSELDMQN--IRDDLAEHLSEGQKRKLTfgIA 628
Cdd:COG0396 75 aRAGIFLAFQYPVEIPGVSVSNFLRTALNARRGEELSAREflkLLKEKMKELGLDEdfLDRYVNEGFSGGEKKRNE--IL 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 629 TVG--DPQILLLDEPTVGLDpfsrqrIW-------GFLKERRADHVILFST---QFMDEadILADRKVLIANGALKCTG 695
Cdd:COG0396 153 QMLllEPKLAILDETDSGLD------IDalrivaeGVNKLRSPDRGILIIThyqRILDY--IKPDFVHVLVDGRIVKSG 223
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
509-691 |
3.74e-12 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 68.58 E-value: 3.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 509 ITAILGHSGAGKSSLLNILSGLYVPTAG-----SVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFdALTVKENLTLFAKI 583
Cdd:PRK14271 49 VTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIFNYRDVLEFRRRVGMLFQRPNPF-PMSIMDNVLAGVRA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 584 KGILPQDVEQEVQQI-LSELDMQN-IRDDLAE---HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLK 658
Cdd:PRK14271 128 HKLVPRKEFRGVAQArLTEVGLWDaVKDRLSDspfRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIR 207
|
170 180 190
....*....|....*....|....*....|...
gi 568976233 659 ERRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:PRK14271 208 SLADRLTVIIVTHNLAQAARISDRAALFFDGRL 240
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
478-667 |
6.01e-12 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 66.67 E-value: 6.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKA 557
Cdd:cd03369 7 IEVENLSVRYAPDLPPV--LKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTI-PLEDLRSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLTLFAkikgilpqdvEQEVQQILSELDMQnirdDLAEHLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03369 84 LTIIPQDPTLFSG-TIRSNLDPFD----------EYSDEEIYGALRVS----EGGLNLSQGQRQLLCLARALLKRPRVLV 148
|
170 180 190
....*....|....*....|....*....|
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHVIL 667
Cdd:cd03369 149 LDEATASIDYATDALIQKTIREEFTNSTIL 178
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1302-1516 |
6.03e-12 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 67.96 E-value: 6.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGdsrAEFGYCPQENGLWPNLTVKEH 1381
Cdd:COG4525 22 ALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLD--GVPVTGPG---ADRGVVFQKDALLPWLNVLDN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQA 1461
Cdd:COG4525 97 VAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQEL 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1462 IQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRcigpIQH-LKRKFGQDYV 1516
Cdd:COG4525 177 LLDVWQRTGKGVFLITHSVEEALFLATRLVVMSPGPGR----IVErLELDFSRRFL 228
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1300-1510 |
7.25e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 67.71 E-value: 7.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE----------LKRLSSAVG---HQGD-----SRA 1361
Cdd:PRK13632 22 NNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKidgitiskenLKEIRKKIGiifQNPDnqfigATV 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1362 E----FGYcpqENGLWPNLTVKEHLELYAAVKGLRkedavvaisrlvnalklhDQLNVQVQNLVAGATRKLCfVLSILGN 1437
Cdd:PRK13632 102 EddiaFGL---ENKKVPPKKMKDIIDDLAKKVGME------------------DYLDKEPQNLSGGQKQRVA-IASVLAL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1438 SP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAeALCDRAAIMVSGRLRCIG-PIQHLKRK 1510
Cdd:PRK13632 160 NPeIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGkPKEILNNK 233
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
509-646 |
8.47e-12 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 70.65 E-value: 8.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 509 ITAILGHSGAGKSSLLNILSGL----YVPTAGSVTVYNKNlsdmqdlKEIRKAI-GVCPQHNVQFDALTVKENLTLFAKI 583
Cdd:PLN03140 908 LTALMGVSGAGKTTLMDVLAGRktggYIEGDIRISGFPKK-------QETFARIsGYCEQNDIHSPQVTVRESLIYSAFL 980
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 584 KgiLPQDVEQE-----VQQILSELDMQNIRDDLA-----EHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PLN03140 981 R--LPKEVSKEekmmfVDEVMELVELDNLKDAIVglpgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD 1051
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1299-1507 |
8.91e-12 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 67.35 E-value: 8.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAG-ITKPTAGQVELKRLSSAVGHQG-------DSRAEFGYCPQEN 1370
Cdd:PRK09984 16 QHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGlITGDKSAGSHIELLGRTVQREGrlardirKSRANTGYIFQQF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1371 GLWPNLTVKEHLELYAA------------VKGLRKEDAVVAISRLVNALKLHDqlnvQVQNLVAGATRKLCFVLSILGNS 1438
Cdd:PRK09984 96 NLVNRLSVLENVLIGALgstpfwrtcfswFTREQKQRALQALTRVGMVHFAHQ----RVSTLSGGQQQRVAIARALMQQA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1439 PVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:PRK09984 172 KVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQF 240
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1306-1498 |
1.21e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 67.04 E-value: 1.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1306 VSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQE-NGLWPNLTVKEHLEL 1384
Cdd:PRK13642 26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKIGMVFQNpDNQFVGATVEDDVAF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1385 YAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQA 1464
Cdd:PRK13642 106 GMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHE 185
|
170 180 190
....*....|....*....|....*....|....
gi 568976233 1465 VVKDNEKGVLLSTHDLAEAeALCDRAAIMVSGRL 1498
Cdd:PRK13642 186 IKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEI 218
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
1274-1498 |
1.23e-11 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 66.78 E-value: 1.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1274 KPVIIASCLHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV--------- 1344
Cdd:TIGR02323 1 KPLLQVSGLSKSYGGGK-----------GCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTAtyimrsgae 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1345 -ELKRLSSAvGHQGDSRAEFGYCPQE--NGLWPNLT----VKEHL-ELYAAVKGLRKEDAVVAISRL-VNALKLHDQlnv 1415
Cdd:TIGR02323 70 lELYQLSEA-ERRRLMRTEWGFVHQNprDGLRMRVSaganIGERLmAIGARHYGNIRATAQDWLEEVeIDPTRIDDL--- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1416 qvQNLVAGATRKLCFVLSILGNSPVLIL-DEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMV 1494
Cdd:TIGR02323 146 --PRAFSGGMQQRLQIARNLVTRPRLVFmDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQ 223
|
....
gi 568976233 1495 SGRL 1498
Cdd:TIGR02323 224 QGRV 227
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1303-1499 |
1.32e-11 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 69.08 E-value: 1.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKptaGQVELKRLSSavGHQGDSRA-----EFGYC--PQE---NGL 1372
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYP---GKFEGNVFIN--GKPVDIRNpaqaiRAGIAmvPEDrkrHGI 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1373 WPNLTVKEHLEL-----YAAVKGLRKEDAVVAISRLVNALKLHD-QLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:TIGR02633 351 VPILGVGKNITLsvlksFCFKMRIDAAAELQIIGSAIQRLKVKTaSPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEP 430
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1447 STGLDVSGKHQVWQAIQAVVKDNEKGVLLSThDLAEAEALCDRAAIMVSGRLR 1499
Cdd:TIGR02633 431 TRGVDVGAKYEIYKLINQLAQEGVAIIVVSS-ELAEVLGLSDRVLVIGEGKLK 482
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
1302-1498 |
1.37e-11 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 69.04 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSsavghQGDSRAEFGYCPQENGLWpNL 1376
Cdd:COG1132 355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRIlidgvDIRDLT-----LESLRRQIGVVPQDTFLF-SG 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLeLYAavkglrKEDA----VVAISRLVNA----LKLHDQLNVQV----QNLVAGATRKLCFVLSILGNSPVLILD 1444
Cdd:COG1132 429 TIRENI-RYG------RPDAtdeeVEEAAKAAQAhefiEALPDGYDTVVgergVNLSGGQRQRIAIARALLKDPPILILD 501
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1445 EPSTGLDVSGKHQVWQAIQAVVKDneKGVLLSTHDLAEAEAlCDRAAIMVSGRL 1498
Cdd:COG1132 502 EATSALDTETEALIQEALERLMKG--RTTIVIAHRLSTIRN-ADRILVLDDGRI 552
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
1302-1504 |
1.53e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 66.99 E-value: 1.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAG------------QVELKRLSSAVGhqgdsrAEFGYcpQE 1369
Cdd:PRK13637 22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGkiiidgvditdkKVKLSDIRKKVG------LVFQY--PE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1370 NGLWPNlTVKEHLELYAAVKGLRKEDAVVAISRLVNALKL-HDQLNVQVQNLVAGATRKLCFVLSILGNSP-VLILDEPS 1447
Cdd:PRK13637 94 YQLFEE-TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLdYEDYKDKSPFELSGGQKRRVAIAGVVAMEPkILILDEPT 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1448 TGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPI 1504
Cdd:PRK13637 173 AGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
478-659 |
1.53e-11 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 63.62 E-value: 1.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsdmqdlkeirka 557
Cdd:cd03221 1 IELENLSKTYGGK----LLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST-------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 igvcpqhnvqfdaltvkenltlfAKIkGILPQdveqevqqilseldmqnirddlaehLSEGQKRKLTFGIATVGDPQILL 637
Cdd:cd03221 63 -----------------------VKI-GYFEQ-------------------------LSGGEKMRLALAKLLLENPNLLL 93
|
170 180
....*....|....*....|..
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKE 659
Cdd:cd03221 94 LDEPTNHLDLESIEALEEALKE 115
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1300-1498 |
1.56e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 66.68 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQ--VELKRLSSAvgHQGDSRAEFGYCPQE-NGLWPNL 1376
Cdd:PRK13650 20 KYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQiiIDGDLLTEE--NVWDIRHKIGMVFQNpDNQFVGA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLRKEDAVvaiSRLVNALKLHDQLNVQVQN---LVAGATRKLCFVLSILGNSPVLILDEPSTGLDVS 1453
Cdd:PRK13650 98 TVEDDVAFGLENKGIPHEEMK---ERVNEALELVGMQDFKEREparLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPE 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 1454 GKHQVWQAIQAVVKDNEKGVLLSTHDLAEAeALCDRAAIMVSGRL 1498
Cdd:PRK13650 175 GRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQV 218
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
1302-1498 |
1.60e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 67.11 E-value: 1.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSsaVGHQGDS------RAEFGYCPQ--ENGLW 1373
Cdd:PRK13646 22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDIT--ITHKTKDkyirpvRKRIGMVFQfpESQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNlTVKEHLELYAAVKGLRKEDAVVAISRLVnaLKLHDQLNVQVQN---LVAGATRKLCFVlSILGNSP-VLILDEPSTG 1449
Cdd:PRK13646 100 ED-TVEREIIFGPKNFKMNLDEVKNYAHRLL--MDLGFSRDVMSQSpfqMSGGQMRKIAIV-SILAMNPdIIVLDEPTAG 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 568976233 1450 LDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK13646 176 LDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSI 224
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
478-741 |
1.71e-11 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 66.80 E-value: 1.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLyVPTAGSVTVYNKNLSDMQdLKEIRKA 557
Cdd:cd03289 3 MTVKDLTAKYTEGGNAV--LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL-LNTEGDIQIDGVSWNSVP-LQKWRKA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDAlTVKENLTLFAKIKGILPQDVEQEV------QQILSELDMQNIrdDLAEHLSEGQKRKLTFGIATVG 631
Cdd:cd03289 79 FGVIPQKVFIFSG-TFRKNLDPYGKWSDEEIWKVAEEVglksviEQFPGQLDFVLV--DGGCVLSHGHKQLMCLARSVLS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 632 DPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMdEADILADRKVLIANGALKCTGS-SVFLKRKwglgyhl 710
Cdd:cd03289 156 KAKILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILSEHRI-EAMLECQRFLVIEENKVRQYDSiQKLLNEK------- 227
|
250 260 270
....*....|....*....|....*....|.
gi 568976233 711 SLFMDETCDSERLTSFINHHIPYAKLKAKTK 741
Cdd:cd03289 228 SHFKQAISPSDRLKLFPRRNSSKSKRKPRPQ 258
|
|
| heterocyst_DevA |
TIGR02982 |
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ... |
1305-1479 |
2.84e-11 |
|
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.
Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 65.04 E-value: 2.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQ-GDSRAEFGYCPQENGLWPNLTVKEH 1381
Cdd:TIGR02982 23 DINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVlgQELHGASKKQlVQLRRRIGYIFQAHNLLGFLTARQN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 ----LELYAAVKGLRKEDAVVAISRLVNalkLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQ 1457
Cdd:TIGR02982 103 vqmaLELQPNLSYQEARERARAMLEAVG---LGDHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEPTAALDSKSGRD 179
|
170 180
....*....|....*....|..
gi 568976233 1458 VWQAIQAVVKDNEKGVLLSTHD 1479
Cdd:TIGR02982 180 VVELMQKLAKEQGCTILMVTHD 201
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1272-1497 |
4.53e-11 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 64.95 E-value: 4.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1272 DEKPVIIASCLHKEYAGQKkhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV------- 1344
Cdd:PRK11701 2 MDQPLLSVRGLTKLYGPRK-----------GCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVhyrmrdg 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1345 ---ELKRLSSAvGHQGDSRAEFGYCPQ--ENGLWPNLT----VKEHLelyAAVkGLR-----KEDAVVAISRL-VNALKL 1409
Cdd:PRK11701 71 qlrDLYALSEA-ERRRLLRTEWGFVHQhpRDGLRMQVSaggnIGERL---MAV-GARhygdiRATAGDWLERVeIDAARI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1410 HD---------QLNVQV-QNLVAGAtrKLCFvlsilgnspvliLDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHD 1479
Cdd:PRK11701 146 DDlpttfsggmQQRLQIaRNLVTHP--RLVF------------MDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHD 211
|
250
....*....|....*...
gi 568976233 1480 LAEAEALCDRAAIMVSGR 1497
Cdd:PRK11701 212 LAVARLLAHRLLVMKQGR 229
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
467-692 |
5.00e-11 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 67.16 E-value: 5.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 467 PVDPEYQGKEAIRIRNIKKeYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPT-AGSVTVYNKNL 545
Cdd:TIGR02633 247 PHEPHEIGDVILEARNLTC-WDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPV 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 546 SDMQDLKEIRKAIGVCPQ----HNVQFDaLTVKENLTLFA--KIKGILPQDVEQEVQQILSELDMQNIRD---DLA-EHL 615
Cdd:TIGR02633 326 DIRNPAQAIRAGIAMVPEdrkrHGIVPI-LGVGKNITLSVlkSFCFKMRIDAAAELQIIGSAIQRLKVKTaspFLPiGRL 404
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 616 SEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQfMDEADILADRKVLIANGALK 692
Cdd:TIGR02633 405 SGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQlaQEGVAIIVVSSE-LAEVLGLSDRVLVIGEGKLK 482
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
1310-1489 |
5.09e-11 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 63.36 E-value: 5.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1310 VNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAvghqgdsraefgYCPQenglwpnltvkehlelYAAVK 1389
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV------------YKPQ----------------YIDLS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1390 GlrkedavvaisrlvnalklhdqlnvqvqnlvaGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDN 1469
Cdd:cd03222 74 G--------------------------------GELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEG 121
|
170 180
....*....|....*....|
gi 568976233 1470 EKGVLLSTHDLAEAEALCDR 1489
Cdd:cd03222 122 KKTALVVEHDLAVLDYLSDR 141
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
477-646 |
6.77e-11 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 66.02 E-value: 6.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYkgkSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEirK 556
Cdd:PRK11650 3 GLKLQAVRKSY---DGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNEL-EPAD--R 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQ---QILsELdmqnirDDLAE----HLSEGQKRKLTFGIAT 629
Cdd:PRK11650 77 DIAMVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAeaaRIL-EL------EPLLDrkprELSGGQRQRVAMGRAI 149
|
170
....*....|....*..
gi 568976233 630 VGDPQILLLDEPTVGLD 646
Cdd:PRK11650 150 VREPAVFLFDEPLSNLD 166
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1310-1507 |
7.16e-11 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 64.39 E-value: 7.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1310 VNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--------KRLSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEH 1381
Cdd:PRK11264 26 VKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidtaRSLSQQKGLIRQLRQHVGFVFQNFNLFPHRTVLEN 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 -LELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQ 1460
Cdd:PRK11264 106 iIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLN 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 568976233 1461 AIQAVVKDNEKGVLLsTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:PRK11264 186 TIRQLAQEKRTMVIV-THEMSFARDVADRAIFMDQGRIVEQGPAKAL 231
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
1297-1505 |
7.76e-11 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 64.52 E-value: 7.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1297 RTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSavgHQGDSRAEFGYCPQ-ENGLWPN 1375
Cdd:PRK15056 17 RNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPT---RQALQKNLVAYVPQsEEVDWSF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 LTVKE---------HLELYAAVKGLRKEDAVVAISRlVNALKLHDQlnvQVQNLVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:PRK15056 94 PVLVEdvvmmgrygHMGWLRRAKKRDRQIVTAALAR-VDMVEFRHR---QIGELSGGQKKRVFLARAIAQQGQVILLDEP 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1447 STGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRaAIMVSGRLRCIGPIQ 1505
Cdd:PRK15056 170 FTGVDVKTEARIISLLRE-LRDEGKTMLVSTHNLGSVTEFCDY-TVMVKGTVLASGPTE 226
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1302-1538 |
7.99e-11 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 66.47 E-value: 7.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDS-RAEFGYCPQENGLWPNLTVKE 1380
Cdd:PRK11288 19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAAlAAGVAIIYQELHLVPEMTVAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HL---ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQ 1457
Cdd:PRK11288 99 NLylgQLPHKGGIVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQ 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1458 VWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL---------------------RCIGPIQHLK-RKFGQdy 1515
Cdd:PRK11288 179 LFRVIRE-LRAEGRVILYVSHRMEEIFALCDAITVFKDGRYvatfddmaqvdrdqlvqamvgREIGDIYGYRpRPLGE-- 255
|
250 260 270
....*....|....*....|....*....|.
gi 568976233 1516 vLELRVKDVS----QEPL---VHR-EILKLF 1538
Cdd:PRK11288 256 -VRLRLDGLKgpglREPIsfsVRAgEIVGLF 285
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
1313-1488 |
8.17e-11 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 64.31 E-value: 8.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1313 GEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAV--GHQGDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKG 1390
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEIldEFRGSELQNYFTKLLEGDVKVIVKPQYVDLIPKAVKG 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1391 -----LRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAV 1465
Cdd:cd03236 106 kvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAARLIREL 185
|
170 180
....*....|....*....|...
gi 568976233 1466 VKDnEKGVLLSTHDLAEAEALCD 1488
Cdd:cd03236 186 AED-DNYVLVVEHDLAVLDYLSD 207
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1302-1352 |
8.73e-11 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 65.48 E-value: 8.73e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSA 1352
Cdd:COG1135 20 ALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVlvdgvDLTALSER 75
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
496-732 |
1.08e-10 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 64.13 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 496 ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdmQDLKEirKAIGVCPQ-HNVQFDALTVK 574
Cdd:PRK15056 22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTR--QALQK--NLVAYVPQsEEVDWSFPVLV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 575 ENLTLFAKI--KGIL----PQDvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPF 648
Cdd:PRK15056 98 EDVVMMGRYghMGWLrrakKRD-RQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 649 SRQRIWGFLKERRAD-HVILFSTQFMDEADILADRKVLI-----ANGALKCTGSSVFLKRKW-GLGYHLSLFMDE---TC 718
Cdd:PRK15056 177 TEARIISLLRELRDEgKTMLVSTHNLGSVTEFCDYTVMVkgtvlASGPTETTFTAENLELAFsGVLRHVALNGSEesiIT 256
|
250
....*....|....
gi 568976233 719 DSERltSFINHHIP 732
Cdd:PRK15056 257 DDER--PFISHRPA 268
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1303-1478 |
1.16e-10 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 62.66 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRlSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHL 1382
Cdd:PRK13540 17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFER-QSIKKDLCTYQKQLCFVGHRSGINPYLTLRENC 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 eLYaavkGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAI 1462
Cdd:PRK13540 96 -LY----DIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKI 170
|
170
....*....|....*.
gi 568976233 1463 QAVVKDNeKGVLLSTH 1478
Cdd:PRK13540 171 QEHRAKG-GAVLLTSH 185
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
1315-1507 |
1.38e-10 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 63.96 E-value: 1.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1315 ILGLLGPDGAGKSSSIRMIAGITKPTAGQvelkRLSSAVGHQGDS----------RAEFGYCPQENGLWPNLTVKEHLEL 1384
Cdd:PRK14271 49 VTSLMGPTGSGKTTFLRTLNRMNDKVSGY----RYSGDVLLGGRSifnyrdvlefRRRVGMLFQRPNPFPMSIMDNVLAG 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1385 YAAVKGL-RKEDAVVAISRLV-----NALKlhDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQV 1458
Cdd:PRK14271 125 VRAHKLVpRKEFRGVAQARLTevglwDAVK--DRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKI 202
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 568976233 1459 WQAIQAVVkdNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:PRK14271 203 EEFIRSLA--DRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQL 249
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
1304-1489 |
1.42e-10 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 60.93 E-value: 1.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrlssavghqgDSRAEFGYCPQENGlwpnltvkehle 1383
Cdd:cd03221 17 KDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW-----------GSTVKIGYFEQLSG------------ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1384 lyaavkglrkedavvaisrlvnalklhdqlnvqvqnlvaGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKhqvwQAIQ 1463
Cdd:cd03221 74 ---------------------------------------GEKMRLALAKLLLENPNLLLLDEPTNHLDLESI----EALE 110
|
170 180
....*....|....*....|....*.
gi 568976233 1464 AVVKDNEKGVLLSTHDLAEAEALCDR 1489
Cdd:cd03221 111 EALKEYPGTVILVSHDRYFLDQVATK 136
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
1272-1503 |
2.03e-10 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 63.98 E-value: 2.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1272 DEKPVIIASCLHKEYAGQKKhcCSRRTRNM--AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV----- 1344
Cdd:COG4608 3 MAEPLLEVRDLKKHFPVRGG--LFGRTVGVvkAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEIlfdgq 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1345 --------ELKRLSSAVghQ----------------GDSRAEfgyCPQENGLWPNLTVKEH-LELYAAVkGLRKEDAV-- 1397
Cdd:COG4608 81 ditglsgrELRPLRRRM--QmvfqdpyaslnprmtvGDIIAE---PLRIHGLASKAERRERvAELLELV-GLRPEHADry 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1398 -----------VAISRlvnALKLHDQLnvqvqnlvagatrklcfvlsilgnspvLILDEPSTGLDVSgkhqvwqaIQAVV 1466
Cdd:COG4608 155 phefsggqrqrIGIAR---ALALNPKL---------------------------IVCDEPVSALDVS--------IQAQV 196
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 568976233 1467 ----KD--NEKGV--LLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:COG4608 197 lnllEDlqDELGLtyLFISHDLSVVRHISDRVAVMYLGKIVEIAP 241
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
1320-1478 |
2.06e-10 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 61.81 E-value: 2.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1320 GPDGAGKSSSIRMIAGITKPTAGQVELKRLSSavghQGDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKglrkeDAVVA 1399
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNI----NNIAKPYCTYIGHNLGLKLEMTVFENLKFWSEIY-----NSAET 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1400 ISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIqaVVKDNEKG-VLLSTH 1478
Cdd:PRK13541 104 LYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLI--VMKANSGGiVLLSSH 181
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1303-1518 |
2.29e-10 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 64.95 E-value: 2.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITK-PTAGQVELKRLSSAVGHQGDS-RAEFGYCPQE---NGLWPNLT 1377
Cdd:PRK13549 278 VDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKIRNPQQAiAQGIAMVPEDrkrDGIVPVMG 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1378 VKEHLEL-----YAAVKGLRKEDAVVAISRLVNALKL---HDQLnvQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTG 1449
Cdd:PRK13549 358 VGKNITLaaldrFTGGSRIDDAAELKTILESIQRLKVktaSPEL--AIARLSGGNQQKAVLAKCLLLNPKILILDEPTRG 435
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1450 LDVSGKHQVWQAIQAVVKDNEKGVLLSThDLAEAEALCDRAAIMVSGRLRCIGPIQHLKrkfgQDYVLE 1518
Cdd:PRK13549 436 IDVGAKYEIYKLINQLVQQGVAIIVISS-ELPEVLGLSDRVLVMHEGKLKGDLINHNLT----QEQVME 499
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
460-653 |
3.07e-10 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 64.74 E-value: 3.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 460 PSDEYFEPVDPEYQGKeaIRIRNIKKEYKgkSGKVkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVT 539
Cdd:PRK10790 325 PRQQYGNDDRPLQSGR--IDIDNVSFAYR--DDNL-VLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIR 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 540 VYNKNLSDMQDlKEIRKAIGVcpqhnVQFDALTVKEnlTLFAKIKgiLPQDV-EQEVQQILSELDMQNIRDDLAE----- 613
Cdd:PRK10790 400 LDGRPLSSLSH-SVLRQGVAM-----VQQDPVVLAD--TFLANVT--LGRDIsEEQVWQALETVQLAELARSLPDglytp 469
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568976233 614 ------HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:PRK10790 470 lgeqgnNLSVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAI 515
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
1302-1498 |
3.30e-10 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 60.79 E-value: 3.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRlSSAVGHQGDSRAEFGYCPQENGLWpNLTVKEH 1381
Cdd:cd03247 17 VLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDG-VPVSDLEKALSSLISVLNQRPYLF-DTTLRNN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LelyaavkGLRkedavvaisrlvnalklhdqlnvqvqnLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQA 1461
Cdd:cd03247 95 L-------GRR---------------------------FSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSL 140
|
170 180 190
....*....|....*....|....*....|....*..
gi 568976233 1462 IQAVVKDneKGVLLSTHDLAEAEALcDRAAIMVSGRL 1498
Cdd:cd03247 141 IFEVLKD--KTLIWITHHLTGIEHM-DKILFLENGKI 174
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1272-1507 |
3.74e-10 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 62.73 E-value: 3.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1272 DEKPVIIASCLHKEYAGQKKHccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVElkrlss 1351
Cdd:PRK13635 1 MKEEIIRVEHISFRYPDAATY---------ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTIT------ 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1352 aVGHQG-------DSRAEFGYCPQEnglwPN-----LTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQN 1419
Cdd:PRK13635 66 -VGGMVlseetvwDVRRQVGMVFQN----PDnqfvgATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHR 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1420 LVAGATRKLCfVLSILGNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAeALCDRAAIMVSGRL 1498
Cdd:PRK13635 141 LSGGQKQRVA-IAGVLALQPdIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEI 218
|
....*....
gi 568976233 1499 RCIGPIQHL 1507
Cdd:PRK13635 219 LEEGTPEEI 227
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
1284-1499 |
3.98e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 61.72 E-value: 3.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1284 KEYAGQKKHCCSRRTrnmavrNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrLSSAVgHQGD--SRA 1361
Cdd:PRK10584 13 KKSVGQGEHELSILT------GVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSL--VGQPL-HQMDeeARA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1362 EF-----GYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILG 1436
Cdd:PRK10584 84 KLrakhvGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNG 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1437 NSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAeALCDRAAIMVSGRLR 1499
Cdd:PRK10584 164 RPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLA-ARCDRRLRLVNGQLQ 225
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
478-649 |
4.30e-10 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 62.34 E-value: 4.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL---------YVPTAGSVTVYNKNLSdm 548
Cdd:PRK09984 5 IRVEKLAKTFNQH----QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgdksagsHIELLGRTVQREGRLA-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 549 QDLKEIRKAIGVCPQHNVQFDALTVKENLTLFAkiKGILP----------QDVEQEVQQILSELDMQNIRDDLAEHLSEG 618
Cdd:PRK09984 79 RDIRKSRANTGYIFQQFNLVNRLSVLENVLIGA--LGSTPfwrtcfswftREQKQRALQALTRVGMVHFAHQRVSTLSGG 156
|
170 180 190
....*....|....*....|....*....|.
gi 568976233 619 QKRKLTFGIATVGDPQILLLDEPTVGLDPFS 649
Cdd:PRK09984 157 QQQRVAIARALMQQAKVILADEPIASLDPES 187
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
492-646 |
4.72e-10 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 62.31 E-value: 4.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlKEIRKAIGVCPQHNVQFDAL 571
Cdd:PRK10253 18 GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYAS-KEVARRIGLLAQNATTPGDI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 572 TVKENLT--------LFAKIKgilpQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTV 643
Cdd:PRK10253 97 TVQELVArgryphqpLFTRWR----KEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTT 172
|
...
gi 568976233 644 GLD 646
Cdd:PRK10253 173 WLD 175
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
1296-1498 |
4.88e-10 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 61.33 E-value: 4.88e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1296 RRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL----------KRLSSAVGHQGDSRAEFGY 1365
Cdd:cd03248 23 TRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLdgkpisqyehKYLHSKVSLVGQEPVLFAR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1366 CPQEN---GLW--PNLTVKEhlelyAAVKGlrkeDAVVAISRLvnALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPV 1440
Cdd:cd03248 103 SLQDNiayGLQscSFECVKE-----AAQKA----HAHSFISEL--ASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQV 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1441 LILDEPSTGLDVSGKHQVWQAIQAVVKDneKGVLLSTHDLAEAEAlCDRAAIMVSGRL 1498
Cdd:cd03248 172 LILDEATSALDAESEQQVQQALYDWPER--RTVLVIAHRLSTVER-ADQILVLDGGRI 226
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
480-646 |
5.22e-10 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 63.20 E-value: 5.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDmqdlKEIR-KAI 558
Cdd:PRK11432 9 LKNITKRF----GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTH----RSIQqRDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLL 638
Cdd:PRK11432 81 CMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160
|
....*...
gi 568976233 639 DEPTVGLD 646
Cdd:PRK11432 161 DEPLSNLD 168
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
502-647 |
5.41e-10 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 62.09 E-value: 5.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 502 LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM--QDLKEIRKAIGVCPQHNVQFDALTVKENLTL 579
Cdd:PRK11831 28 LTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMsrSRLYTVRKRMSMLFQSGALFTDMNVFDNVAY 107
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 580 FAKIKGILPQDV-EQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:PRK11831 108 PLREHTQLPAPLlHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDP 176
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1302-1497 |
6.95e-10 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 62.43 E-value: 6.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSS----IRMIA--GITKPTA----------GQVELKRLssavghqgdsRAE--- 1362
Cdd:PRK09473 31 AVNDLNFSLRAGETLGIVGESGSGKSQTafalMGLLAanGRIGGSAtfngreilnlPEKELNKL----------RAEqis 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1363 --FgycpQE--NGLWPNLTVKEHL-ELYAAVKGLRKEDAVVAISRLVNALKL---HDQLNVQVQNLVAGATRKLCFVLSI 1434
Cdd:PRK09473 101 miF----QDpmTSLNPYMRVGEQLmEVLMLHKGMSKAEAFEESVRMLDAVKMpeaRKRMKMYPHEFSGGMRQRVMIAMAL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1435 LGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK09473 177 LCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 239
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
1302-1513 |
7.05e-10 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 61.76 E-value: 7.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVElkrlssavghqgdSRAEFGYCPQENGLWPNLTVKEH 1381
Cdd:PRK13546 39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVD-------------RNGEVSVIAISAGLSGQLTGIEN 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQA 1461
Cdd:PRK13546 106 IEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDK 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1462 IQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQ 1513
Cdd:PRK13546 186 IYE-FKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEA 236
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1275-1513 |
7.86e-10 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 61.63 E-value: 7.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1275 PVIIASCLHKEYAGQKkhCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV--------EL 1346
Cdd:PRK10419 2 TLLNVSGLSHHYAHGG--LSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVswrgeplaKL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1347 KRlSSAVGHQGDSRAEFGYCPqeNGLWPNLTVKEHL-ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQV-QNLVAGA 1424
Cdd:PRK10419 80 NR-AQRKAFRRDIQMVFQDSI--SAVNPRKTVREIIrEPLRHLLSLDKAERLARASEMLRAVDLDDSVLDKRpPQLSGGQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1425 TRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL---RCI 1501
Cdd:PRK10419 157 LQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIvetQPV 236
|
250
....*....|..
gi 568976233 1502 GPIQHLKRKFGQ 1513
Cdd:PRK10419 237 GDKLTFSSPAGR 248
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
478-689 |
7.87e-10 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 60.18 E-value: 7.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVK-ALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKnlsdmqdlkeirk 556
Cdd:cd03250 1 ISVEDASFTWDSGEQETSfTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 aIGVCPQ----HNvqfdaLTVKENLtLFAKikgilPQDvEQEVQQILS----ELDMQNIRD-DLAE------HLSEGQKR 621
Cdd:cd03250 68 -IAYVSQepwiQN-----GTIRENI-LFGK-----PFD-EERYEKVIKacalEPDLEILPDgDLTEigekgiNLSGGQKQ 134
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 622 KLTFGIATVGDPQILLLDEPTVGLDPFSRQRIW-----GFLKERRAdhVILF--STQFMDEadilADRKVLIANG 689
Cdd:cd03250 135 RISLARAVYSDADIYLLDDPLSAVDAHVGRHIFencilGLLLNNKT--RILVthQLQLLPH----ADQIVVLDNG 203
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
481-646 |
8.50e-10 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 60.35 E-value: 8.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 481 RNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL---YVPTAGSVTvYNKNlsDMQDLKEIRKA 557
Cdd:cd03233 7 RNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRtegNVSVEGDIH-YNGI--PYKEFAEKYPG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 -IGVCPQHNVQFDALTVKENLTLFAKIKGilpqdveqevqqilseldMQNIRDdlaehLSEGQKRKLTFGIATVGDPQIL 636
Cdd:cd03233 84 eIIYVSEEDVHFPTLTVRETLDFALRCKG------------------NEFVRG-----ISGGERKRVSIAEALVSRASVL 140
|
170
....*....|
gi 568976233 637 LLDEPTVGLD 646
Cdd:cd03233 141 CWDNSTRGLD 150
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
478-642 |
8.87e-10 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 63.10 E-value: 8.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGksgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVtVYNKNLSDMQDLKEIRKA 557
Cdd:PRK10762 5 LQLKGIDKAFPG----VKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSI-LYLGKEVTFNGPKSSQEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 -IGVCPQHNVQFDALTVKENLTL----FAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGD 632
Cdd:PRK10762 80 gIGIIHQELNLIPQLTIAENIFLgrefVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFE 159
|
170
....*....|
gi 568976233 633 PQILLLDEPT 642
Cdd:PRK10762 160 SKVIIMDEPT 169
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
508-653 |
9.42e-10 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 63.36 E-value: 9.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 508 QITAILGHSGAGKSSLLNILSGLYVPT--AGSVTVYNKNLSdmqdlKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKg 585
Cdd:PLN03211 95 EILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPT-----KQILKRTGFVTQDDILYPHLTVRETLVFCSLLR- 168
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 586 iLPQDVEQEV-----QQILSELDMQN-----IRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:PLN03211 169 -LPKSLTKQEkilvaESVISELGLTKcentiIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRL 245
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
477-646 |
1.04e-09 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 62.99 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVtvynknlsdmqdlKEIRK 556
Cdd:PRK15064 319 ALEVENLTKGFDNG----PLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV-------------KWSEN 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 A-IGVCPQ-HNVQFDaltvkENLTLF---AKIKGilPQDVEQEVQQILSELDMQNirDDL---AEHLSEGQKRKLTFGIA 628
Cdd:PRK15064 382 AnIGYYAQdHAYDFE-----NDLTLFdwmSQWRQ--EGDDEQAVRGTLGRLLFSQ--DDIkksVKVLSGGEKGRMLFGKL 452
|
170
....*....|....*...
gi 568976233 629 TVGDPQILLLDEPTVGLD 646
Cdd:PRK15064 453 MMQKPNVLVMDEPTNHMD 470
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
1302-1498 |
1.11e-09 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 61.68 E-value: 1.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGIT----KPTAGQVE-----LKRLSSA-----VGhqgdsrAEFGYCP 1367
Cdd:PRK11022 22 AVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIdypgRVMAEKLEfngqdLQRISEKerrnlVG------AEVAMIF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1368 QE--NGLWPNLTVKehLELYAAVK----GLRKEDAVVAISrLVNALKLHD---QLNVQVQNLVAGATRKLCFVLSILGNS 1438
Cdd:PRK11022 96 QDpmTSLNPCYTVG--FQIMEAIKvhqgGNKKTRRQRAID-LLNQVGIPDpasRLDVYPHQLSGGMSQRVMIAMAIACRP 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1439 PVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK11022 173 KLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQV 232
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
1298-1537 |
1.25e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 61.35 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1298 TRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKP-TAGQVELKRLSSAVGHQG--DSRAEFGYCPQE-NGLW 1373
Cdd:PRK13640 18 SKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPdDNPNSKITVDGITLTAKTvwDIREKVGIVFQNpDNQF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCfVLSILGNSP-VLILDEPSTGLDV 1452
Cdd:PRK13640 98 VGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVA-IAGILAVEPkIIILDESTSMLDP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1453 SGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEA-----LCDRAAIMVSGRLRCIGPIQHLKRKFGQDYvlelrvkdvsqe 1527
Cdd:PRK13640 177 AGKEQILKLIRKLKKKNNLTVISITHDIDEANMadqvlVLDDGKLLAQGSPVEIFSKVEMLKEIGLDI------------ 244
|
250
....*....|
gi 568976233 1528 PLVHREILKL 1537
Cdd:PRK13640 245 PFVYKLKNKL 254
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
1305-1510 |
1.40e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 61.00 E-value: 1.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQG--DSRAEFGYCPQ--ENGLWPNlTV 1378
Cdd:PRK13641 25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIagYHITPETGNKNlkKLRKKVSLVFQfpEAQLFEN-TV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQL-NVQVQNLVAGATRKLCfVLSILGNSP-VLILDEPSTGLDVSGKH 1456
Cdd:PRK13641 104 LKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDLiSKSPFELSGGQMRRVA-IAGVMAYEPeILCLDEPAAGLDPEGRK 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1457 QVWQaiqaVVKDNEKG---VLLSTHDLAEAEALCDRAAIMVSGRLrcigpIQHLKRK 1510
Cdd:PRK13641 183 EMMQ----LFKDYQKAghtVILVTHNMDDVAEYADDVLVLEHGKL-----IKHASPK 230
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
1303-1511 |
1.40e-09 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 63.20 E-value: 1.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVElkrlsSAVGHQGDS--------RAEFGYCPQENGLWP 1374
Cdd:TIGR00956 77 LKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFHIGVE-----GVITYDGITpeeikkhyRGDVVYNAETDVHFP 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKEHLELYAA-------VKGLRKEDAVVAISRLVNA-LKLHDQLNVQVQNL----VAGATRK-LCFVLSILGNSPVL 1441
Cdd:TIGR00956 152 HLTVGETLDFAARcktpqnrPDGVSREEYAKHIADVYMAtYGLSHTRNTKVGNDfvrgVSGGERKrVSIAEASLGGAKIQ 231
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAE-AEALCDRAAIMVSGRLRCIGPIQHLKRKF 1511
Cdd:TIGR00956 232 CWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSQdAYELFDKVIVLYEGYQIYFGPADKAKQYF 302
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1302-1498 |
1.53e-09 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 59.89 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRL-SSAVGHQgdsRAEFGYCPQENGLWPN 1375
Cdd:PRK10908 17 ALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIwfsghDITRLkNREVPFL---RRQIGMIFQDHHLLMD 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 LTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQL-NVQVQnLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSG 1454
Cdd:PRK10908 94 RTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAkNFPIQ-LSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDAL 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568976233 1455 KHQVWQAIQAVvkdNEKG--VLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK10908 173 SEGILRLFEEF---NRVGvtVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1282-1498 |
1.75e-09 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 61.36 E-value: 1.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYAGQKKhccsrrtRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAVGHQ 1356
Cdd:PRK11153 7 ISKVFPQGGR-------TIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVlvdgqDLTALSEKELRK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 gdSRAEFGYCPQENGLWPNLTVKEH----LELyaavKGLRKEDavvaISRLVNAL----KLHDQLNVQVQNLVAGATRKl 1428
Cdd:PRK11153 80 --ARRQIGMIFQHFNLLSSRTVFDNvalpLEL----AGTPKAE----IKARVTELlelvGLSDKADRYPAQLSGGQKQR- 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1429 cfvLSI---LGNSP-VLILDEPSTGLDvsgkHQVWQAIQAVVKD-NEK---GVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK11153 149 ---VAIaraLASNPkVLLCDEATSALD----PATTRSILELLKDiNRElglTIVLITHEMDVVKRICDRVAVIDAGRL 219
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
479-646 |
1.78e-09 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 60.32 E-value: 1.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 479 RIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNK--NLSDMQDLKE--- 553
Cdd:PRK11701 8 SVRGLTKLY----GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRdgQLRDLYALSEaer 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 ---IRKAIGVCPQHNVqfDAL--------TVKENL-TLFAKIKGILPQDVEQEVQQIlsELDMQNIrDDLAEHLSEGQKR 621
Cdd:PRK11701 84 rrlLRTEWGFVHQHPR--DGLrmqvsaggNIGERLmAVGARHYGDIRATAGDWLERV--EIDAARI-DDLPTTFSGGMQQ 158
|
170 180
....*....|....*....|....*
gi 568976233 622 KLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PRK11701 159 RLQIARNLVTHPRLVFMDEPTGGLD 183
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1305-1482 |
1.86e-09 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 59.73 E-value: 1.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNlTVKEHLEL 1384
Cdd:PRK10247 25 NISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYCAQTPTLFGD-TVYDNLIF 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1385 YAAVKGLRKEDAVVAISRLVNALKLHdQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQA 1464
Cdd:PRK10247 104 PWQIRNQQPDPAIFLDDLERFALPDT-ILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHR 182
|
170
....*....|....*...
gi 568976233 1465 VVKDNEKGVLLSTHDLAE 1482
Cdd:PRK10247 183 YVREQNIAVLWVTHDKDE 200
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
502-691 |
2.38e-09 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 61.99 E-value: 2.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 502 LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQD----------LKEIRKAIG----------VC 561
Cdd:PRK15439 284 LEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTaqrlarglvyLPEDRQSSGlyldaplawnVC 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 562 --PQHNVQFDALTVKENLTL--FAKIKGILPQDVEQEVQQilseldmqnirddlaehLSEGQKRKLTFGIATVGDPQILL 637
Cdd:PRK15439 364 alTHNRRGFWIKPARENAVLerYRRALNIKFNHAEQAART-----------------LSGGNQQKVLIAKCLEASPQLLI 426
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 638 LDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANGAL 691
Cdd:PRK15439 427 VDEPTRGVDVSARNDIYQLIRSIAAQNVaVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1302-1497 |
2.49e-09 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 60.25 E-value: 2.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQG--DSRAEFGYCPQ--ENGLWpNLT 1377
Cdd:PRK13636 21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRKGlmKLRESVGMVFQdpDNQLF-SAS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1378 VKEHLElYAAVKGLRKEDAVVaiSRLVNALKlhdqlNVQVQNLVAGATRKLCF-------VLSILGNSP-VLILDEPSTG 1449
Cdd:PRK13636 100 VYQDVS-FGAVNLKLPEDEVR--KRVDNALK-----RTGIEHLKDKPTHCLSFgqkkrvaIAGVLVMEPkVLVLDEPTAG 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568976233 1450 LDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK13636 172 LDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGR 219
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
1302-1498 |
2.64e-09 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 59.04 E-value: 2.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLS-SAVGHQgDSRAEFGYCPQEnglwPNL---T 1377
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDiSKIGLH-DLRSRISIIPQD----PVLfsgT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1378 VKEHL---------ELYAAVKGlrkedavVAISRLVNALKlhDQLNVQVQ----NLVAGATRKLCFVLSILGNSPVLILD 1444
Cdd:cd03244 94 IRSNLdpfgeysdeELWQALER-------VGLKEFVESLP--GGLDTVVEeggeNLSVGQRQLLCLARALLRKSKILVLD 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1445 EPSTGLDVSGKHQVWQAIQAVVKDNEkgVLLSTHDLaEAEALCDRAAIMVSGRL 1498
Cdd:cd03244 165 EATASVDPETDALIQKTIREAFKDCT--VLTIAHRL-DTIIDSDRILVLDKGRV 215
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
497-741 |
2.67e-09 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 62.24 E-value: 2.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLyVPTAGSVTVYNKNLSDMQdLKEIRKAIGVCPQHNVQFDAlTVKEN 576
Cdd:TIGR01271 1235 LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL-LSTEGEIQIDGVSWNSVT-LQTWRKAFGVIPQKVFIFSG-TFRKN 1311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 577 LTLFAKIKGILPQDVEQEV------QQILSELDMQNIrdDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSR 650
Cdd:TIGR01271 1312 LDPYEQWSDEEIWKVAEEVglksviEQFPDKLDFVLV--DGGYVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTL 1389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 651 QRIWGFLKERRADHVILFSTQFMdEADILADRKVLIANGALKCTGSsvfLKRkwgLGYHLSLFMDETCDSERLTSFINHH 730
Cdd:TIGR01271 1390 QIIRKTLKQSFSNCTVILSEHRV-EALLECQQFLVIEGSSVKQYDS---IQK---LLNETSLFKQAMSAADRLKLFPLHR 1462
|
250
....*....|.
gi 568976233 731 IPYAKLKAKTK 741
Cdd:TIGR01271 1463 RNSSKRKPQPK 1473
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
1302-1509 |
2.69e-09 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 59.80 E-value: 2.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCV-------------NKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAvghQGDSRA---EFGY 1365
Cdd:PRK10575 13 ALRNVSFRVpgrtllhplsltfPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLE---SWSSKAfarKVAY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1366 CPQENGLWPNLTVKEHLEL-----YAAVKGLRKED--------AVVAISRLVNALklhdqlnvqVQNLVAGATRKLCFVL 1432
Cdd:PRK10575 90 LPQQLPAAEGMTVRELVAIgrypwHGALGRFGAADrekveeaiSLVGLKPLAHRL---------VDSLSGGERQRAWIAM 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1433 SILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKR 1509
Cdd:PRK10575 161 LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMR 237
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1312-1488 |
3.06e-09 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 61.75 E-value: 3.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1312 KGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE--------------------LKRLSsavghQGDSRAefGYCPQENG 1371
Cdd:PRK13409 98 EGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEeepswdevlkrfrgtelqnyFKKLY-----NGEIKV--VHKPQYVD 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNltvkehlelyaAVKG-----LRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:PRK13409 171 LIPK-----------VFKGkvrelLKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP 239
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1447 STGLDVSGKHQVWQAIQAVVKDneKGVLLSTHDLAEAEALCD 1488
Cdd:PRK13409 240 TSYLDIRQRLNVARLIRELAEG--KYVLVVEHDLAVLDYLAD 279
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
1299-1518 |
3.27e-09 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 60.48 E-value: 3.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYcpQENGLWPNLTV 1378
Cdd:PRK10851 14 RTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVF--QHYALFRHMTV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQL----NVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSG 1454
Cdd:PRK10851 92 FDNIAFGLTVLPRRERPNAAAIKAKVTQLLEMVQLahlaDRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQV 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1455 KHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLE 1518
Cdd:PRK10851 172 RKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLE 235
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
1303-1510 |
3.86e-09 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 58.31 E-value: 3.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGI--TKPTAGQVELKrlssavGH-----QGDSRAEFG--YCPQEnglw 1373
Cdd:cd03217 16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFK------GEditdlPPEERARLGifLAFQY---- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PnltvkehlelyAAVKGLRKEDAVvaisRLVNAlklhdqlnvqvqnLVAGATRKLCFVLSILGNSPVL-ILDEPSTGLDV 1452
Cdd:cd03217 86 P-----------PEIPGVKNADFL----RYVNE-------------GFSGGEKKRNEILQLLLLEPDLaILDEPDSGLDI 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1453 SGKHQVWQAIQAVVKDNeKGVLLSTH-----DLAEAealcDRAAIMVSGRLRCIGP---IQHLKRK 1510
Cdd:cd03217 138 DALRLVAEVINKLREEG-KSVLIITHyqrllDYIKP----DRVHVLYDGRIVKSGDkelALEIEKK 198
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
1303-1467 |
4.47e-09 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 58.04 E-value: 4.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTA---GQVELKrlssavGHQGDS-----RAEFGYCPQENGLWP 1374
Cdd:cd03233 23 LKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVsveGDIHYN------GIPYKEfaekyPGEIIYVSEEDVHFP 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKEHLELYAAVKGlrkeDAVVaisRLVNalklhdqlnvqvqnlvaGATRKLcfvLSI----LGNSPVLILDEPSTGL 1450
Cdd:cd03233 97 TLTVRETLDFALRCKG----NEFV---RGIS-----------------GGERKR---VSIaealVSRASVLCWDNSTRGL 149
|
170
....*....|....*..
gi 568976233 1451 DVSGKHQVWQAIQAVVK 1467
Cdd:cd03233 150 DSSTALEILKCIRTMAD 166
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
493-682 |
4.53e-09 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 60.79 E-value: 4.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 493 KVKALKGLFLD-----IYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDM--QD--------LKEIRKA 557
Cdd:PRK10762 259 KVDNLSGPGVNdvsftLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRspQDglangivyISEDRKR 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPqhnvqfdALTVKENLTL-----FAKIKGILpqDVEQEVQQILSELDMQNI----RDDLAEHLSEGQKRKLTFGIA 628
Cdd:PRK10762 339 DGLVL-------GMSVKENMSLtalryFSRAGGSL--KHADEQQAVSDFIRLFNIktpsMEQAIGLLSGGNQQKVAIARG 409
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 629 TVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRAD--HVILFSTQfMDEADILADR 682
Cdd:PRK10762 410 LMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEglSIILVSSE-MPEVLGMSDR 464
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
492-646 |
4.83e-09 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 60.24 E-value: 4.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQH---NVQF 568
Cdd:PRK09536 14 GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEAL-SARAASRRVASVPQDtslSFEF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 569 DALTVKE-----NLTLFAkikGILPQDvEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTV 643
Cdd:PRK09536 93 DVRQVVEmgrtpHRSRFD---TWTETD-RAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTA 168
|
...
gi 568976233 644 GLD 646
Cdd:PRK09536 169 SLD 171
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
1303-1531 |
5.15e-09 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 60.57 E-value: 5.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSS---SI------RMIAGITKPTAGQVELKRLSSAVGHqGdsraeFGYCPQ---EN 1370
Cdd:NF040905 276 VDDVSLNVRRGEIVGIAGLMGAGRTElamSVfgrsygRNISGTVFKDGKEVDVSTVSDAIDA-G-----LAYVTEdrkGY 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1371 GLwpNL--TVKEHLELyAAVKGLRKEDAVVAISRLVNALKLHDQLNV-------QVQNLVAGATRKLcfVLS--ILGNSP 1439
Cdd:NF040905 350 GL--NLidDIKRNITL-ANLGKVSRRGVIDENEEIKVAEEYRKKMNIktpsvfqKVGNLSGGNQQKV--VLSkwLFTDPD 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1440 VLILDEPSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLrcigpiqhlkrkfgqdyVLEL 1519
Cdd:NF040905 425 VLILDEPTRGIDVGAKYEIYTIINELAAEG-KGVIVISSELPELLGMCDRIYVMNEGRI-----------------TGEL 486
|
250
....*....|..
gi 568976233 1520 RVKDVSQEPLVH 1531
Cdd:NF040905 487 PREEASQERIMR 498
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
478-697 |
5.26e-09 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 59.03 E-value: 5.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSG-----KVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS------ 546
Cdd:PRK15112 5 LEVRNLSKTFRYRTGwfrrqTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfgdysy 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 547 DMQDLKEIRK--AIGVCPQHNV-QFDALTVKENLTLfakikgilpqDVEQEVQQILSELDMQNIRDDLAEH----LSEGQ 619
Cdd:PRK15112 85 RSQRIRMIFQdpSTSLNPRQRIsQILDFPLRLNTDL----------EPEQREKQIIETLRQVGLLPDHASYyphmLAPGQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 620 KRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVI--LFSTQFMDEADILADRKVLIANGALKCTGSS 697
Cdd:PRK15112 155 KQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGIsyIYVTQHLGMMKHISDQVLVMHQGEVVERGST 234
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1300-1497 |
5.37e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 58.94 E-value: 5.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK-----RLSSavgHQgdsRAEF----------G 1364
Cdd:COG1101 19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDgkdvtKLPE---YK---RAKYigrvfqdpmmG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1365 YCpqenglwPNLTVKEHLELYA----------AVKGLRKEDAVVAISRLvnALKLHDQLNVQVQNLVAGATRKLCFVLSI 1434
Cdd:COG1101 93 TA-------PSMTIEENLALAYrrgkrrglrrGLTKKRRELFRELLATL--GLGLENRLDTKVGLLSGGQRQALSLLMAT 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1435 LGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:COG1101 164 LTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGR 226
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
1305-1478 |
6.60e-09 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 57.25 E-value: 6.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGitKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHLEL 1384
Cdd:cd03232 25 NISGYVKPGTLTALMGESGAGKTTLLDVLAG--RKTAGVITGEILINGRPLDKNFQRSTGYVEQQDVHSPNLTVREALRF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1385 YAAVKGLRKEDavvaisrlvnalklhdqlnvqvqnlvagatRKLcfvLSI---LGNSPVLI-LDEPSTGLDVSGKHQVWQ 1460
Cdd:cd03232 103 SALLRGLSVEQ------------------------------RKR---LTIgveLAAKPSILfLDEPTSGLDSQAAYNIVR 149
|
170
....*....|....*...
gi 568976233 1461 AIQAVVkDNEKGVLLSTH 1478
Cdd:cd03232 150 FLKKLA-DSGQAILCTIH 166
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
508-646 |
6.91e-09 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 58.65 E-value: 6.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 508 QITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlKEIRKAIGVCPQHNVQFDALTVKENLTL----FAKI 583
Cdd:PRK10575 38 KVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS-KAFARKVAYLPQQLPAAEGMTVRELVAIgrypWHGA 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 584 KGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PRK10575 117 LGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
478-646 |
7.12e-09 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 57.54 E-value: 7.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKsgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL--YVPTAGSVTVYNKNLSDMQDLKEIR 555
Cdd:cd03217 1 LEIKDLHVSVGGK----EILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEDITDLPPEERAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHNVQFDALTVKENLtlfakikgilpqdveqevqqilseldmqniRdDLAEHLSEGQKRKLTFGIATVGDPQI 635
Cdd:cd03217 77 LGIFLAFQYPPEIPGVKNADFL------------------------------R-YVNEGFSGGEKKRNEILQLLLLEPDL 125
|
170
....*....|.
gi 568976233 636 LLLDEPTVGLD 646
Cdd:cd03217 126 AILDEPDSGLD 136
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
1303-1498 |
7.14e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 58.52 E-value: 7.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGH---QGDS---RAEFGYCPQENGLWPNL 1376
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKdifQIDAiklRKEVGMVFQQPNPFPHL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLRKEDAVVAIS----RLVNALK-LHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLD 1451
Cdd:PRK14246 106 SIYDNIAYPLKSHGIKEKREIKKIVeeclRKVGLWKeVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMID 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 568976233 1452 VSGKhqvwQAIQAVVKD--NEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK14246 186 IVNS----QAIEKLITElkNEIAIVIVSHNPQQVARVADYVAFLYNGEL 230
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
1299-1501 |
8.62e-09 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 60.13 E-value: 8.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDSRAeFGYCPQE---NGLW 1373
Cdd:PRK10982 260 RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLhgKKINNHNANEAINHG-FALVTEErrsTGIY 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVkEHLELYAAVKGLRKEDAVVAISRLVNALK-LHDQLNV-------QVQNLVAGATRKLCFVLSILGNSPVLILDE 1445
Cdd:PRK10982 339 AYLDI-GFNSLISNIRNYKNKVGLLDNSRMKSDTQwVIDSMRVktpghrtQIGSLSGGNQQKVIIGRWLLTQPEILMLDE 417
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1446 PSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLRCI 1501
Cdd:PRK10982 418 PTRGIDVGAKFEIYQLIAELAKKD-KGIIIISSEMPELLGITDRILVMSNGLVAGI 472
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
512-653 |
9.44e-09 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 57.42 E-value: 9.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 512 ILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDlKEIRKAIGVCPQHNVQFDAlTVKENLTLFAKIKGILPqdv 591
Cdd:PRK10247 38 ITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKP-EIYRQQVSYCAQTPTLFGD-TVYDNLIFPWQIRNQQP--- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 592 eqevqqilselDMQNIRDDLA-------------EHLSEGQK------RKLTFGiatvgdPQILLLDEPTVGLDPFSRQR 652
Cdd:PRK10247 113 -----------DPAIFLDDLErfalpdtiltkniAELSGGEKqrisliRNLQFM------PKVLLLDEITSALDESNKHN 175
|
.
gi 568976233 653 I 653
Cdd:PRK10247 176 V 176
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
462-691 |
9.57e-09 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 59.65 E-value: 9.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 462 DEYFEPVDPEyQGKEAIRIRNIKKEykgksgkvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVY 541
Cdd:COG1129 242 EDLFPKRAAA-PGEVVLEVEGLSVG--------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLD 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 542 NKNLS-----DMQDLK-----EIRKAIGVCPQhnvqfdaLTVKENLTL-----FAKiKGILPQDVEQE-VQQILSELdmq 605
Cdd:COG1129 313 GKPVRirsprDAIRAGiayvpEDRKGEGLVLD-------LSIRENITLasldrLSR-GGLLDRRRERAlAEEYIKRL--- 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 606 NIR----DDLAEHLSEGQKRKLTFG--IATvgDPQILLLDEPTVGLDPFSRQRIWGFLKERRAD--HVILFSTQfMDEAD 677
Cdd:COG1129 382 RIKtpspEQPVGNLSGGNQQKVVLAkwLAT--DPKVLILDEPTRGIDVGAKAEIYRLIRELAAEgkAVIVISSE-LPELL 458
|
250
....*....|....
gi 568976233 678 ILADRKVLIANGAL 691
Cdd:COG1129 459 GLSDRILVMREGRI 472
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1295-1503 |
9.83e-09 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 59.87 E-value: 9.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1295 SRRTRNM-AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAVGHQGDS-RAEFGYCPQE- 1369
Cdd:PRK10261 331 NRVTREVhAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFngQRIDTLSPGKLQAlRRDIQFIFQDp 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1370 -NGLWPNLTVKEHLELYAAVKGLRKEDAVVA-ISRLVNALKLHDQLNVQVQNLVAGATR-KLCFVLSILGNSPVLILDEP 1446
Cdd:PRK10261 411 yASLDPRQTVGDSIMEPLRVHGLLPGKAAAArVAWLLERVGLLPEHAWRYPHEFSGGQRqRICIARALALNPKVIIADEA 490
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1447 STGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:PRK10261 491 VSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGP 547
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
1299-1503 |
1.08e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 57.93 E-value: 1.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1299 RNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITK--PTA---GQVEL--KRLSSAVGHQGDSRAEFGYCPQENG 1371
Cdd:PRK14267 16 SNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElnEEArveGEVRLfgRNIYSPDVDPIEVRREVGMVFQYPN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNLTVKEH----LELYAAVKGLRKEDAVVAISRLVNAL--KLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDE 1445
Cdd:PRK14267 96 PFPHLTIYDNvaigVKLNGLVKSKKELDERVEWALKKAALwdEVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDE 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1446 PSTGLDVSGKHQVWQAIQAVvkDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGP 1503
Cdd:PRK14267 176 PTANIDPVGTAKIEELLFEL--KKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGP 231
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1302-1489 |
1.13e-08 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 57.44 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKR------LSSAVGHQ--GDSRAEFGYCPQenglw 1373
Cdd:COG4778 26 VLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHdggwvdLAQASPREilALRRRTIGYVSQ----- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 pNLTV---KEHLELYAAVKGLRKEDAVVAISRlvnALKLHDQLNVQvQNL--VAGAT------------RklCFVlsilG 1436
Cdd:COG4778 101 -FLRViprVSALDVVAEPLLERGVDREEARAR---ARELLARLNLP-ERLwdLPPATfsggeqqrvniaR--GFI----A 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1437 NSPVLILDEPSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDR 1489
Cdd:COG4778 170 DPPLLLLDEPTASLDAANRAVVVELIEE-AKARGTAIIGIFHDEEVREAVADR 221
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1274-1516 |
1.24e-08 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 57.86 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1274 KPVIIASCLHKeYAGQKKhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMI-------------------- 1333
Cdd:PRK14239 3 EPILQVSDLSV-YYNKKK----------ALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrmndlnpevtitgsivyng 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1334 AGITKPTAGQVELkrlssavghqgdsRAEFGYCPQENGLWPnLTVKEHLELYAAVKGLRKE---DAVVAISrLVNAL--- 1407
Cdd:PRK14239 72 HNIYSPRTDTVDL-------------RKEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKDKqvlDEAVEKS-LKGASiwd 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1408 KLHDQLNVQVQNLVAGATRKLCfVLSILGNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEkgVLLSTHDLAEAEAL 1486
Cdd:PRK14239 137 EVKDRLHDSALGLSGGQQQRVC-IARVLATSPkIILLDEPTSALDPISAGKIEETLLGLKDDYT--MLLVTRSMQQASRI 213
|
250 260 270
....*....|....*....|....*....|....
gi 568976233 1487 CDRAAIMVSGRLRCIGPIQHL----KRKFGQDYV 1516
Cdd:PRK14239 214 SDRTGFFLDGDLIEYNDTKQMfmnpKHKETEDYI 247
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
1313-1478 |
1.43e-08 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 59.51 E-value: 1.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1313 GEILGLLGPDGAGKSSSIRMIAG-----------------ITKPTagqveLKRLssavghqgdsraefGYCPQENGLWPN 1375
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALAGriqgnnftgtilannrkPTKQI-----LKRT--------------GFVTQDDILYPH 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 LTVKEHL---ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNL----VAGATRK-LCFVLSILGNSPVLILDEPS 1447
Cdd:PLN03211 155 LTVRETLvfcSLLRLPKSLTKQEKILVAESVISELGLTKCENTIIGNSfirgISGGERKrVSIAHEMLINPSLLILDEPT 234
|
170 180 190
....*....|....*....|....*....|.
gi 568976233 1448 TGLDVSGKHQVWQAIQAVVKDNeKGVLLSTH 1478
Cdd:PLN03211 235 SGLDATAAYRLVLTLGSLAQKG-KTIVTSMH 264
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
1298-1482 |
1.55e-08 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 57.24 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1298 TRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlssavGH-----QGDS-RAEFGYCPQENG 1371
Cdd:cd03253 12 PGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILID------GQdirevTLDSlRRAIGVVPQDTV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWpNLTVKEHL----------ELYAAVKGLRKEDAVvaisrlvnaLKLHDQLNVQVQN----LVAGATRKLCFVLSILGN 1437
Cdd:cd03253 86 LF-NDTIGYNIrygrpdatdeEVIEAAKAAQIHDKI---------MRFPDGYDTIVGErglkLSGGEKQRVAIARAILKN 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 1438 SPVLILDEPSTGLDVSGKHQVWQAIQAVVKDneKGVLLSTHDLAE 1482
Cdd:cd03253 156 PPILLLDEATSALDTHTEREIQAALRDVSKG--RTTIVIAHRLST 198
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1298-1498 |
1.62e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 57.79 E-value: 1.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1298 TRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRL-SSAVGHQGDSRAEFGYCPQ--ENGLWP 1374
Cdd:PRK13633 21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLdTSDEENLWDIRNKAGMVFQnpDNQIVA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLtVKEHLELYAAVKGLRKEDAVvaiSRLVNALKLHDQLNVQ--VQNLVAGATRKLCFVLSILGNSP-VLILDEPSTGLD 1451
Cdd:PRK13633 101 TI-VEEDVAFGPENLGIPPEEIR---ERVDESLKKVGMYEYRrhAPHLLSGGQKQRVAIAGILAMRPeCIIFDEPTAMLD 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 568976233 1452 VSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAeALCDRAAIMVSGRL 1498
Cdd:PRK13633 177 PSGRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGKV 222
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
478-684 |
1.84e-08 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 57.39 E-value: 1.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYK-----GKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLS--DMQD 550
Cdd:PRK10419 4 LNVSGLSHHYAhgglsGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAklNRAQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 551 LKEIRKAI---------GVCPQHNVQFdalTVKENLTlfaKIKGILPQDVEQEVQQILSELDMQ-NIRDDLAEHLSEGQK 620
Cdd:PRK10419 84 RKAFRRDIqmvfqdsisAVNPRKTVRE---IIREPLR---HLLSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 621 RKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQ-------------FMDEADILADRKV 684
Cdd:PRK10419 158 QRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKlqQQFGTACLFITHdlrlverfcqrvmVMDNGQIVETQPV 236
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
1300-1539 |
1.88e-08 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 57.56 E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSS----SIRMIAgitkpTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPN 1375
Cdd:cd03289 17 NAVLENISFSISPGQRVGLLGRTGSGKSTllsaFLRLLN-----TEGDIQIDGVSWNSVPLQKWRKAFGVIPQKVFIFSG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 lTVKEHLELYaavkGLRKEDAVVAISRLVnALKL-----HDQLNVQVQN----LVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:cd03289 92 -TFRKNLDPY----GKWSDEEIWKVAEEV-GLKSvieqfPGQLDFVLVDggcvLSHGHKQLMCLARSVLSKAKILLLDEP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1447 STGLDVSgkhqVWQAIQAVVKDNEKG--VLLSTHDLaEAEALCDRAAIMVSGRLRCIGPIQHLkrkfgqdyvleLRVKDV 1524
Cdd:cd03289 166 SAHLDPI----TYQVIRKTLKQAFADctVILSEHRI-EAMLECQRFLVIEENKVRQYDSIQKL-----------LNEKSH 229
|
250
....*....|....*
gi 568976233 1525 SQEPLVHREILKLFP 1539
Cdd:cd03289 230 FKQAISPSDRLKLFP 244
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
1302-1498 |
2.52e-08 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 55.88 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQEnglwPNL---TV 1378
Cdd:cd03369 23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTIIPQD----PTLfsgTI 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELYAavkglRKEDAvvaisRLVNALKLHDQLNvqvqNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHqv 1458
Cdd:cd03369 99 RSNLDPFD-----EYSDE-----EIYGALRVSEGGL----NLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDA-- 162
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568976233 1459 wqAIQAVVKDNEKGVLLST--HDLAEAeALCDRAAIMVSGRL 1498
Cdd:cd03369 163 --LIQKTIREEFTNSTILTiaHRLRTI-IDYDKILVMDAGEV 201
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
1302-1502 |
2.52e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 57.33 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV---------ELKRLSSAvghqGDSRAEFGYCPQ--EN 1370
Cdd:PRK13645 26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTivgdyaipaNLKKIKEV----KRLRKEIGLVFQfpEY 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1371 GLWPNlTVKEHLELYAAVKGLRKEDAVVAISRLVNALKL-HDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTG 1449
Cdd:PRK13645 102 QLFQE-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGG 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1450 LDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:PRK13645 181 LDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIG 233
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
1313-1498 |
2.58e-08 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 56.99 E-value: 2.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1313 GEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKR--LSSAvghQGDSRAEFgycpQENGLWPNLTVKEHLELyaAVKG 1390
Cdd:PRK11247 38 GQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTapLAEA---REDTRLMF----QDARLLPWKKVIDNVGL--GLKG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1391 LRKEDAVVAIsrlvNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNE 1470
Cdd:PRK11247 109 QWRDAALQAL----AAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHG 184
|
170 180
....*....|....*....|....*...
gi 568976233 1471 KGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK11247 185 FTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
1298-1497 |
2.67e-08 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 55.94 E-value: 2.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1298 TRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGitkptagqvELKRLSSAVGHQGdsraEFGYCPQENglW-PNL 1376
Cdd:cd03250 16 ETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLG---------ELEKLSGSVSVPG----SIAYVSQEP--WiQNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKE----HLELYAavkglRKEDAVVAISRLVNALK-LHDQLNVQVQ----NLVAGATRKLCFVLSILGNSPVLILDEPS 1447
Cdd:cd03250 81 TIREnilfGKPFDE-----ERYEKVIKACALEPDLEiLPDGDLTEIGekgiNLSGGQKQRISLARAVYSDADIYLLDDPL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1448 TGLDVS-GKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEAlCDRAAIMVSGR 1497
Cdd:cd03250 156 SAVDAHvGRHIFENCILGLLLNN-KTRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
478-646 |
2.85e-08 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 56.66 E-value: 2.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVtvynknlsdmqdLKEIRKA 557
Cdd:PRK09544 5 VSLENVSVSF----GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI------------KRNGKLR 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQhNVQFDA---LTVKENLTLFAKIKG--ILPqdveqevqqILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGD 632
Cdd:PRK09544 69 IGYVPQ-KLYLDTtlpLTVNRFLRLRPGTKKedILP---------ALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNR 138
|
170
....*....|....
gi 568976233 633 PQILLLDEPTVGLD 646
Cdd:PRK09544 139 PQLLVLDEPTQGVD 152
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1304-1502 |
3.47e-08 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 57.35 E-value: 3.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL--KRLSSAvghqGDSRAEFGYCPQENGLWPNLTVKEH 1381
Cdd:PRK11000 20 KDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIgeKRMNDV----PPAERGVGMVFQSYALYPHLSVAEN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDavvaISRLVNA----LKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQ 1457
Cdd:PRK11000 96 MSFGLKLAGAKKEE----INQRVNQvaevLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQ 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 1458 VWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:PRK11000 172 MRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVG 216
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
478-651 |
4.20e-08 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 57.98 E-value: 4.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLF----------------LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVtvy 541
Cdd:PRK13545 5 VKFEHVTKKYKMYNKPFDKLKDLFfrskdgeyhyalnnisFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV--- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 542 nknlsdmqDLKEIRKAIGVCPQHNVQfdaLTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKR 621
Cdd:PRK13545 82 --------DIKGSAALIAISSGLNGQ---LTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKS 150
|
170 180 190
....*....|....*....|....*....|.
gi 568976233 622 KLTFGIATVGDPQILLLDEP-TVGLDPFSRQ 651
Cdd:PRK13545 151 RLGFAISVHINPDILVIDEAlSVGDQTFTKK 181
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
477-646 |
4.25e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 58.60 E-value: 4.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 477 AIRIRNIKKEYKGKSGKVkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRK 556
Cdd:PLN03130 1237 SIKFEDVVLRYRPELPPV--LHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKF-GLMDLRK 1313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 557 AIGVCPQHNVQFDAlTVKENLTLF--------------AKIKGIL---PQDVEQEVQQIlseldmqnirddlAEHLSEGQ 619
Cdd:PLN03130 1314 VLGIIPQAPVLFSG-TVRFNLDPFnehndadlweslerAHLKDVIrrnSLGLDAEVSEA-------------GENFSVGQ 1379
|
170 180
....*....|....*....|....*..
gi 568976233 620 KRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PLN03130 1380 RQLLSLARALLRRSKILVLDEATAAVD 1406
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1312-1481 |
5.21e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 57.49 E-value: 5.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1312 KGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE--------------------LKRLSSavghqGDSRAefGYCPQENG 1371
Cdd:COG1245 98 KGKVTGILGPNGIGKSTALKILSGELKPNLGDYDeepswdevlkrfrgtelqdyFKKLAN-----GEIKV--AHKPQYVD 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNL---TVKEHLElyaavkglrKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPST 1448
Cdd:COG1245 171 LIPKVfkgTVRELLE---------KVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSS 241
|
170 180 190
....*....|....*....|....*....|...
gi 568976233 1449 GLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLA 1481
Cdd:COG1245 242 YLDIYQRLNVARLIRELAEEG-KYVLVVEHDLA 273
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
435-646 |
5.33e-08 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 58.12 E-value: 5.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 435 LNPTSCFRKTANRNKVIERDLDPELPSDeyfepvdpeyqgKEAIRIRNIKKEYKGKSgKVKALKGLFLDIYESQITAILG 514
Cdd:PTZ00265 352 LEATNSLYEIINRKPLVENNDDGKKLKD------------IKKIQFKNVRFHYDTRK-DVEIYKDLNFTLTEGKTYAFVG 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 515 HSGAGKSSLLNILSGLYVPTAGSVTVYNK-NLSDMqDLKEIRKAIGVCPQ----------HNVQFDALTVK--------- 574
Cdd:PTZ00265 419 ESGCGKSTILKLIERLYDPTEGDIIINDShNLKDI-NLKWWRSKIGVVSQdpllfsnsikNNIKYSLYSLKdlealsnyy 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 575 --------ENLTLFAKIKGILPQDVEQEVQ--------------QILSELDMQNIRDDL--------------------A 612
Cdd:PTZ00265 498 nedgndsqENKNKRNSCRAKCAGDLNDMSNttdsneliemrknyQTIKDSEVVDVSKKVlihdfvsalpdkyetlvgsnA 577
|
250 260 270
....*....|....*....|....*....|....
gi 568976233 613 EHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PTZ00265 578 SKLSGGQKQRISIARAIIRNPKILILDEATSSLD 611
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
401-671 |
5.61e-08 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 56.24 E-value: 5.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 401 FILAFDSLLYLVLALYFDKILLYGAEHRSAPLFFLNPTS-------CFRKTANRNKVIERDLDPELPSDEYFEPVDPEYQ 473
Cdd:pfam13304 15 LLEALRFLADFDALVIGLTDERSRNGGIGGIPSLLNGIDpkepiefEISEFLEDGVRYRYGLDLEREDVEEKLSSKPTLL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAIL---GHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQD 550
Cdd:pfam13304 95 EKRLLLREDSEEREPKFPPEAEELRLGLDVEERIELSLSElsdLISGLLLLSIISPLSFLLLLDEGLLLEDWAVLDLAAD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 551 LKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDdlAEHLSEGQKRKLTFGIA-- 628
Cdd:pfam13304 175 LALFPDLKELLQRLVRGLKLADLNLSDLGEGIEKSLLVDDRLRERGLILLENGGGGELP--AFELSDGTKRLLALLAAll 252
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 568976233 629 -TVGDPQILLLDEPTVGLDPFSRQRIWGFLKE-RRADHVILFSTQ 671
Cdd:pfam13304 253 sALPKGGLLLIDEPESGLHPKLLRRLLELLKElSRNGAQLILTTH 297
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
1296-1507 |
6.28e-08 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 57.42 E-value: 6.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1296 RRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL----------KRLSSAVGHQGdsraefgy 1365
Cdd:TIGR00958 490 NRPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLdgvplvqydhHYLHRQVALVG-------- 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1366 cpQENGLWpNLTVKEHLeLYaavkGLRK--EDAVVAISRLVNA----LKLHDQLNVQV----QNLVAGATRKLCFVLSIL 1435
Cdd:TIGR00958 562 --QEPVLF-SGSVRENI-AY----GLTDtpDEEIMAAAKAANAhdfiMEFPNGYDTEVgekgSQLSGGQKQRIAIARALV 633
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1436 GNSPVLILDEPSTGLDVsgkhQVWQAIQAVVKDNEKGVLLSTHDLAEAEAlCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:TIGR00958 634 RKPRVLILDEATSALDA----ECEQLLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQL 700
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
1305-1480 |
6.59e-08 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 55.03 E-value: 6.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV----ELKRLSSAVGHQGDSRAEFGYCPQENGLWpNLTVKE 1380
Cdd:cd03290 19 NINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVhwsnKNESEPSFEATRSRNRYSVAYAAQKPWLL-NATVEE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HLELYAAVKGLRKEDAVVAISRL--VNALKLHDQLNVQVQ--NLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVS-GK 1455
Cdd:cd03290 98 NITFGSPFNKQRYKAVTDACSLQpdIDLLPFGDQTEIGERgiNLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHlSD 177
|
170 180
....*....|....*....|....*
gi 568976233 1456 HQVWQAIQAVVKDNEKGVLLSTHDL 1480
Cdd:cd03290 178 HLMQEGILKFLQDDKRTLVLVTHKL 202
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
1291-1485 |
6.72e-08 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 54.80 E-value: 6.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1291 KHCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKP---TAGQVEL--KRLSSAVGHQgdsRAeFGY 1365
Cdd:COG4136 5 ENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLngRRLTALPAEQ---RR-IGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1366 CPQENGLWPNLTVKEHLeLYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDE 1445
Cdd:COG4136 81 LFQDDLLFPHLSVGENL-AFALPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDE 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568976233 1446 PSTGLD----VSGKHQVWQAIQavvkdnEKG--VLLSTHDLAEAEA 1485
Cdd:COG4136 160 PFSKLDaalrAQFREFVFEQIR------QRGipALLVTHDEEDAPA 199
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
512-657 |
7.49e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 56.95 E-value: 7.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 512 ILGHSGAGKSSLLNILSGLYvPTAGS--VTVYNKNLSDMQDLKEIRKAIG-VCPQHNVQFDALTVKENLTL---FAKIkG 585
Cdd:PRK10938 291 IVGPNGAGKSTLLSLITGDH-PQGYSndLTLFGRRRGSGETIWDIKKHIGyVSSSLHLDYRVSTSVRNVILsgfFDSI-G 368
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 586 ILpQDVEQEVQQILSE-LDMQNIRDDLAEH----LSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFL 657
Cdd:PRK10938 369 IY-QAVSDRQQKLAQQwLDILGIDKRTADApfhsLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFV 444
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1305-1507 |
7.53e-08 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 55.10 E-value: 7.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDS--RAEFGYCPQENGLWPNLTVKEHL 1382
Cdd:PRK09493 19 NIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERliRQEAGMVFQQFYLFPHLTALENV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 ELYAA-VKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSiLGNSPVLIL-DEPSTGLDVSGKHQVWQ 1460
Cdd:PRK09493 99 MFGPLrVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARA-LAVKPKLMLfDEPTSALDPELRHEVLK 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 568976233 1461 AIQAVVKDNEKGVLLsTHDLAEAEALCDRAAIMVSGRLRCIGPIQHL 1507
Cdd:PRK09493 178 VMQDLAEEGMTMVIV-THEIGFAEKVASRLIFIDKGRIAEDGDPQVL 223
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
1269-1452 |
8.49e-08 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 56.87 E-value: 8.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1269 PNLDEKpVIIASCLHKEYaGQKkhccsrrtrnMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkr 1348
Cdd:TIGR03719 316 PRLGDK-VIEAENLTKAF-GDK----------LLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-- 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1349 lssavghqGDSrAEFGYCPQE-NGLWPNLTVKE-------HLELyaavkGLRKEDAVVAISRLvnALKLHDQlnvqvQNL 1420
Cdd:TIGR03719 382 --------GET-VKLAYVDQSrDALDPNKTVWEeisggldIIKL-----GKREIPSRAYVGRF--NFKGSDQ-----QKK 440
|
170 180 190
....*....|....*....|....*....|....*...
gi 568976233 1421 V---AGATRKLCFVLSIL---GNspVLILDEPSTGLDV 1452
Cdd:TIGR03719 441 VgqlSGGERNRVHLAKTLksgGN--VLLLDEPTNDLDV 476
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
1297-1468 |
1.08e-07 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 54.47 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1297 RTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQEnglwPNL 1376
Cdd:cd03249 13 RPDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIGLVSQE----PVL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 ---TVKEHLeLYAavKGLRKEDAVVAISRLVNA----LKLHDQLNVQVQN----LVAGATRKLCFVLSILGNSPVLILDE 1445
Cdd:cd03249 89 fdgTIAENI-RYG--KPDATDEEVEEAAKKANIhdfiMSLPDGYDTLVGErgsqLSGGQKQRIAIARALLRNPKILLLDE 165
|
170 180
....*....|....*....|...
gi 568976233 1446 PSTGLDVSGKHQVWQAIQAVVKD 1468
Cdd:cd03249 166 ATSALDAESEKLVQEALDRAMKG 188
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1302-1537 |
1.08e-07 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 56.35 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGIT--KPTAGQVeLKRLS-----------SAVGHQGdSRAEFGYCPQ 1368
Cdd:TIGR03269 15 VLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRI-IYHVAlcekcgyverpSKVGEPC-PVCGGTLEPE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1369 ENGLW-PNLTVKEHLELYAAVK-----GLRKEDAVV----------------AISRlvnALKLHDQLNVQ------VQNL 1420
Cdd:TIGR03269 93 EVDFWnLSDKLRRRIRKRIAIMlqrtfALYGDDTVLdnvlealeeigyegkeAVGR---AVDLIEMVQLShrithiARDL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1421 VAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRC 1500
Cdd:TIGR03269 170 SGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENGEIKE 249
|
250 260 270
....*....|....*....|....*....|....*....
gi 568976233 1501 IGPIQHLKRKFgqdyvLELrVKDVSQ--EPLVHREILKL 1537
Cdd:TIGR03269 250 EGTPDEVVAVF-----MEG-VSEVEKecEVEVGEPIIKV 282
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1304-1484 |
1.09e-07 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 56.66 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-------------ELKRLssavghqgdSRAEFGYCPQEN 1370
Cdd:PRK10535 25 KGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYrvagqdvatldadALAQL---------RREHFGFIFQRY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1371 GLWPNLTVKEHLELYAAVKGL----RKEDAVVAISRlvnaLKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:PRK10535 96 HLLSHLTAAQNVEVPAVYAGLerkqRLLRAQELLQR----LGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEP 171
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 568976233 1447 STGLDVSGKHQVwQAIQAVVKDNEKGVLLSTHD---LAEAE 1484
Cdd:PRK10535 172 TGALDSHSGEEV-MAILHQLRDRGHTVIIVTHDpqvAAQAE 211
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
443-646 |
1.27e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 56.91 E-value: 1.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 443 KTANRNKVIER-----DLDPELPS-DEYFEPVDpEYQGKEAIRIRNIKKEYKgkSGKVKALKGLFLDIYESQITAILGHS 516
Cdd:PLN03232 1195 KAENSLNSVERvgnyiDLPSEATAiIENNRPVS-GWPSRGSIKFEDVHLRYR--PGLPPVLHGLSFFVSPSEKVGVVGRT 1271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 517 GAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFDAlTVKENLTLFAkikgilpqdvEQEVQ 596
Cdd:PLN03232 1272 GAGKSSMLNALFRIVELEKGRIMIDDCDVAKF-GLTDLRRVLSIIPQSPVLFSG-TVRFNIDPFS----------EHNDA 1339
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 597 QILSELDMQNIRDDL--------------AEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PLN03232 1340 DLWEALERAHIKDVIdrnpfgldaevsegGENFSVGQRQLLSLARALLRRSKILVLDEATASVD 1403
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
480-646 |
1.35e-07 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 55.48 E-value: 1.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQD--LKEIRKA 557
Cdd:PRK15079 20 IKDGKQWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDdeWRAVRSD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQhnvqfDALT-----------VKENL-TLFAKIKGilpQDVEQEVQQILSELDM-QNIRDDLAEHLSEGQKRKLT 624
Cdd:PRK15079 100 IQMIFQ-----DPLAslnprmtigeiIAEPLrTYHPKLSR---QEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIG 171
|
170 180
....*....|....*....|..
gi 568976233 625 FGIATVGDPQILLLDEPTVGLD 646
Cdd:PRK15079 172 IARALILEPKLIICDEPVSALD 193
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
466-646 |
1.58e-07 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 55.85 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 466 EPVDPEYQGKEAIRIRNIKKEYKGKSG-------KVKALKGLFLDIYESQITAILGHSGAGKSSL-LNILsGLyVPTAGS 537
Cdd:COG4172 264 DPRPVPPDAPPLLEARDLKVWFPIKRGlfrrtvgHVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALL-RL-IPSEGE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 538 VTVYNKNLSDM--QDLKEIRKAIGVC---------PQHNVqfdALTVKENLTLFAkiKGILPQDVEQEVQQILSE--LDm 604
Cdd:COG4172 342 IRFDGQDLDGLsrRALRPLRRRMQVVfqdpfgslsPRMTV---GQIIAEGLRVHG--PGLSAAERRARVAEALEEvgLD- 415
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568976233 605 qnirDDLAE---H-LSEGQKRKLtfGIA--TVGDPQILLLDEPTVGLD 646
Cdd:COG4172 416 ----PAARHrypHeFSGGQRQRI--AIAraLILEPKLLVLDEPTSALD 457
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
1302-1468 |
1.64e-07 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 56.12 E-value: 1.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLS-SAVGHQGDSRAeFGYCPQENGLWpNLTVKE 1380
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDiRTVTRASLRRN-IAVVFQDAGLF-NRSIED 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1381 HL----------ELYAAVKGLRKEDAVvaisrlvnaLKLHDQLNVQV----QNLVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:PRK13657 428 NIrvgrpdatdeEMRAAAERAQAHDFI---------ERKPDGYDTVVgergRQLSGGERQRLAIARALLKDPPILILDEA 498
|
170 180
....*....|....*....|..
gi 568976233 1447 STGLDVSGKHQVWQAIQAVVKD 1468
Cdd:PRK13657 499 TSALDVETEAKVKAALDELMKG 520
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
1282-1507 |
1.66e-07 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 54.59 E-value: 1.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1282 LHKEYaGQKKhccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK------------RL 1349
Cdd:PRK10619 11 LHKRY-GEHE----------VLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNgqtinlvrdkdgQL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1350 SSAVGHQGDS-RAEFGYCPQENGLWPNLTVKEH-LELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRK 1427
Cdd:PRK10619 80 KVADKNQLRLlRTRLTMVFQHFNLWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1428 LCFVLSILGNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNeKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQH 1506
Cdd:PRK10619 160 RVSIARALAMEPeVLLFDEPTSALDPELVGEVLRIMQQLAEEG-KTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQ 238
|
.
gi 568976233 1507 L 1507
Cdd:PRK10619 239 L 239
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
1300-1497 |
1.79e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 54.36 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQEnglwPN---- 1375
Cdd:PRK13647 18 TKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLVFQD----PDdqvf 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 -LTVKEHLELYAAVKGLRKEDAvvaISRLVNALKLhdqlnVQVQNLVAGATRKLCF-------VLSILGNSP-VLILDEP 1446
Cdd:PRK13647 94 sSTVWDDVAFGPVNMGLDKDEV---ERRVEEALKA-----VRMWDFRDKPPYHLSYgqkkrvaIAGVLAMDPdVIVLDEP 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1447 STGLDVSGKHQVwQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK13647 166 MAYLDPRGQETL-MEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGR 215
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
1304-1497 |
2.10e-07 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 54.22 E-value: 2.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAvghqgDSRAEFGYCPQENGLWPNLTV 1378
Cdd:PRK10253 24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVwldgeHIQHYASK-----EVARRIGLLAQNATTPGDITV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KE--------HLELYAAvkgLRKEDAvVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGL 1450
Cdd:PRK10253 99 QElvargrypHQPLFTR---WRKEDE-EAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 568976233 1451 DVSgkHQVwQAIQAVVKDN-EKGVLLST--HDLAEAealCDRAAIMVSGR 1497
Cdd:PRK10253 175 DIS--HQI-DLLELLSELNrEKGYTLAAvlHDLNQA---CRYASHLIALR 218
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1303-1497 |
2.37e-07 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 55.48 E-value: 2.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKS----SSIRMIAgiTKPT---------AGQVELKRLSSAV-GHQGDSRAEFGYCPQ 1368
Cdd:PRK15134 25 VNDVSLQIEAGETLALVGESGSGKSvtalSILRLLP--SPPVvypsgdirfHGESLLHASEQTLrGVRGNKIAMIFQEPM 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1369 ENgLWPNLTVKEHL-ELYAAVKGLRKEDAVVAISRLVNALKLHD---QLNVQVQNLVAGATRKLCFVLSILGNSPVLILD 1444
Cdd:PRK15134 103 VS-LNPLHTLEKQLyEVLSLHRGMRREAARGEILNCLDRVGIRQaakRLTDYPHQLSGGERQRVMIAMALLTRPELLIAD 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1445 EPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK15134 182 EPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
476-692 |
3.03e-07 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 53.67 E-value: 3.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 476 EAIRIRNIKKEY----------------KGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVT 539
Cdd:PRK13546 3 VSVNIKNVTKEYriyrtnkermkdalipKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 540 VYNknlsdmqDLKEIRKAIGVCPQhnvqfdaLTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQ 619
Cdd:PRK13546 83 RNG-------EVSVIAISAGLSGQ-------LTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGM 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568976233 620 KRKLTFGIATVGDPQILLLDEP-TVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALK 692
Cdd:PRK13546 149 RAKLGFSINITVNPDILVIDEAlSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLK 222
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
507-650 |
3.36e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 52.57 E-value: 3.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 507 SQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQdlKEIRKAIGvcpqHNVQFDA-LTVKENLTLFAKIkg 585
Cdd:PRK13541 26 SAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIA--KPYCTYIG----HNLGLKLeMTVFENLKFWSEI-- 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 586 ilpQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSR 650
Cdd:PRK13541 98 ---YNSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR 159
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1302-1507 |
3.38e-07 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 55.08 E-value: 3.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKS----SSIRMIAGITKPTAGQV-----ELKRLSSAV--GHQGDsraEFGYCPQE- 1369
Cdd:COG4172 25 AVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSIlfdgqDLLGLSERElrRIRGN---RIAMIFQEp 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1370 ----NglwPNLTV----KEHLELYaavKGLRKEDAvvaisrLVNALKLHDQlnVQVQNlvagATRKLC---FVLS----- 1433
Cdd:COG4172 102 mtslN---PLHTIgkqiAEVLRLH---RGLSGAAA------RARALELLER--VGIPD----PERRLDaypHQLSggqrq 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1434 ---I---LGNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQH 1506
Cdd:COG4172 164 rvmIamaLANEPdLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAE 243
|
.
gi 568976233 1507 L 1507
Cdd:COG4172 244 L 244
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
1316-1479 |
3.58e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 54.94 E-value: 3.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1316 LGLLGPDGAGKSSSIRMIAGITKPTAGQvelkrlssAVGHQGdsrAEFGYCPQENGLWPNLTVKEHLELYAA--VKGLRK 1393
Cdd:TIGR03719 34 IGVLGLNGAGKSTLLRIMAGVDKDFNGE--------ARPQPG---IKVGYLPQEPQLDPTKTVRENVEEGVAeiKDALDR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1394 EDAVVA------------------ISRLVNALKLHD---QLNV------------QVQNLVAGATRK--LCFVLsiLGNS 1438
Cdd:TIGR03719 103 FNEISAkyaepdadfdklaaeqaeLQEIIDAADAWDldsQLEIamdalrcppwdaDVTKLSGGERRRvaLCRLL--LSKP 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 568976233 1439 PVLILDEPSTGLD---VSgkhqvWqaIQAVVKDNEKGVLLSTHD 1479
Cdd:TIGR03719 181 DMLLLDEPTNHLDaesVA-----W--LERHLQEYPGTVVAVTHD 217
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
514-647 |
3.70e-07 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 52.54 E-value: 3.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 514 GHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIrKAIGVCPQHNVQFDALtvkENLTLFAKIKGILPQdveQ 593
Cdd:PRK13543 44 GDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFM-AYLGHLPGLKADLSTL---ENLHFLCGLHGRRAK---Q 116
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 594 EVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:PRK13543 117 MPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
1302-1521 |
3.86e-07 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 54.83 E-value: 3.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWpNLTVKEH 1381
Cdd:PRK11160 355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISVVSQRVHLF-SATLRDN 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGlrkEDAVVAISRLVNALKLHDQ---LNVQV----QNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSG 1454
Cdd:PRK11160 434 LLLAAPNAS---DEALIEVLQQVGLEKLLEDdkgLNAWLgeggRQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAET 510
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1455 KHQVWQAIQAVVKDneKGVLLSTHDLAEAEALcDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLELRV 1521
Cdd:PRK11160 511 ERQILELLAEHAQN--KTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELLAQQGRYYQLKQRL 574
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1297-1512 |
4.16e-07 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 53.29 E-value: 4.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1297 RTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAG-ITKPTA-------GQVEL----------KRLS--SAVGHQ 1356
Cdd:PRK13547 11 RRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdLTGGGAprgarvtGDVTLngeplaaidaPRLArlRAVLPQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 GDSRAeFGYCPQEN---GLWPNLT---VKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAgatrKLCF 1430
Cdd:PRK13547 91 AAQPA-FAFSAREIvllGRYPHARragALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLA----QLWP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1431 VLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPI------ 1504
Cdd:PRK13547 166 PHDAAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPadvltp 245
|
....*...
gi 568976233 1505 QHLKRKFG 1512
Cdd:PRK13547 246 AHIARCYG 253
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
499-646 |
5.51e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 54.48 E-value: 5.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 499 GLFLDiyeSQItAILGHSGAGKSSLLNILSGLYVPTAGSVtvynknlsdmqdLKEIRKAIGVCPQHNVqfDALTVKENLT 578
Cdd:PLN03073 531 GIDLD---SRI-AMVGPNGIGKSTILKLISGELQPSSGTV------------FRSAKVRMAVFSQHHV--DGLDLSSNPL 592
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 579 LFakIKGILPQDVEQEVQQILSELdmqNIRDDLAEH----LSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PLN03073 593 LY--MMRCFPGVPEQKLRAHLGSF---GVTGNLALQpmytLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
514-671 |
5.53e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 51.87 E-value: 5.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 514 GHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdmQDLKEIRKAIGVCPQHNVQFDALTVKENlTLFakikGILPQDVEQ 593
Cdd:PRK13540 34 GSNGAGKTTLLKLIAGLLNPEKGEILFERQSIK--KDLCTYQKQLCFVGHRSGINPYLTLREN-CLY----DIHFSPGAV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 594 EVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRAD--HVILFSTQ 671
Cdd:PRK13540 107 GITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQEHRAKggAVLLTSHQ 186
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
475-667 |
5.59e-07 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 54.25 E-value: 5.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 475 KEAIRIRNIKKEYKGKsgKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQdLKEI 554
Cdd:PRK11176 339 KGDIEFRNVTFTYPGK--EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYT-LASL 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 555 RKAIGVCPQhNVQFDALTVKENLTlFAKIKGILPQDVEQEVQ-----QILSELDmQNIRDDLAEH---LSEGQKRKLTFG 626
Cdd:PRK11176 416 RNQVALVSQ-NVHLFNDTIANNIA-YARTEQYSREQIEEAARmayamDFINKMD-NGLDTVIGENgvlLSGGQRQRIAIA 492
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 568976233 627 IATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVIL 667
Cdd:PRK11176 493 RALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSL 533
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
512-651 |
5.68e-07 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 54.41 E-value: 5.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 512 ILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsdmqdLKEIRkaIGVCPQHNVQFdaLTVKEN-LTLFAKIKgilPQD 590
Cdd:PRK10636 343 LLGRNGAGKSTLIKLLAGELAPVSGEIGL----------AKGIK--LGYFAQHQLEF--LRADESpLQHLARLA---PQE 405
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 591 VEQEVQQILSELDMQNIR-DDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQ 651
Cdd:PRK10636 406 LEQKLRDYLGGFGFQGDKvTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQ 467
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1302-1497 |
6.01e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 54.06 E-value: 6.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGItKPTA---GQV-----ELKrlssAVGHQGDSRAEFGYCPQENGLW 1373
Cdd:TIGR02633 16 ALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHGtwdGEIywsgsPLK----ASNIRDTERAGIVIIHQELTLV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1374 PNLTVKEHLELYAAV--KGLRKEDA--VVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILG-NSPVLILDEPST 1448
Cdd:TIGR02633 91 PELSVAENIFLGNEItlPGGRMAYNamYLRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNkQARLLILDEPSS 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568976233 1449 GLdvsgKHQVWQAIQAVVKD-NEKGV--LLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:TIGR02633 171 SL----TEKETEILLDIIRDlKAHGVacVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
503-682 |
6.96e-07 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 52.41 E-value: 6.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 503 DIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSdmqdlkeiRKAIGVCPQHNVQFDALtvkenltLFAK 582
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS--------YKPQYIKADYEGTVRDL-------LSSI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 583 IKGILPQDveQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDpfSRQR------IWGF 656
Cdd:cd03237 86 TKDFYTHP--YFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLD--VEQRlmaskvIRRF 161
|
170 180 190
....*....|....*....|....*....|.
gi 568976233 657 LKERRA-----DHVILFstqfmdeADILADR 682
Cdd:cd03237 162 AENNEKtafvvEHDIIM-------IDYLADR 185
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
474-691 |
7.20e-07 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 53.63 E-value: 7.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 474 GKEAIRIRNIKKEYKGKsgkvkaLKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKE 553
Cdd:PRK09700 262 HETVFEVRNVTSRDRKK------VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDA 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 554 IRKAIGVCPQH---NVQFDALTVKENLTLFAKIK--------GILPQDVEQ---EVQQILSELDMQNIRDDLAEhLSEGQ 619
Cdd:PRK09700 336 VKKGMAYITESrrdNGFFPNFSIAQNMAISRSLKdggykgamGLFHEVDEQrtaENQRELLALKCHSVNQNITE-LSGGN 414
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 620 KRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRAD-HVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:PRK09700 415 QQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDgKVILMVSSELPEIITVCDRIAVFCEGRL 487
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
480-645 |
7.65e-07 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 53.58 E-value: 7.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYKGksgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLsDMQDLKE-IRKAI 558
Cdd:PRK10982 1 MSNISKSFPG----VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEI-DFKSSKEaLENGI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 559 GVCPQHNVQFDALTVKENLTL--FAKIKGILPQD-VEQEVQQILSELDMQ-NIRDDLAEhLSEGQKRKLTFGIATVGDPQ 634
Cdd:PRK10982 76 SMVHQELNLVLQRSVMDNMWLgrYPTKGMFVDQDkMYRDTKAIFDELDIDiDPRAKVAT-LSVSQMQMIEIAKAFSYNAK 154
|
170
....*....|.
gi 568976233 635 ILLLDEPTVGL 645
Cdd:PRK10982 155 IVIMDEPTSSL 165
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
481-645 |
8.76e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 53.39 E-value: 8.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 481 RNIKKEYKGksgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY--------VPTAGSVTVYnKNLSDMQdlk 552
Cdd:PRK13549 9 KNITKTFGG----VKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYphgtyegeIIFEGEELQA-SNIRDTE--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 eiRKAIGVCPQHNVQFDALTVKENLTLFAKI--KGILPQD-VEQEVQQILSELDMqNIRDDL-AEHLSEGQKRKLTFGIA 628
Cdd:PRK13549 81 --RAGIAIIHQELALVKELSVLENIFLGNEItpGGIMDYDaMYLRAQKLLAQLKL-DINPATpVGNLGLGQQQLVEIAKA 157
|
170
....*....|....*..
gi 568976233 629 TVGDPQILLLDEPTVGL 645
Cdd:PRK13549 158 LNKQARLLILDEPTASL 174
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
1302-1497 |
9.16e-07 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 52.79 E-value: 9.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV-----ELKRLSSAVGHqgDSRAEFGYCPQE--NGLWP 1374
Cdd:PRK15079 36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVawlgkDLLGMKDDEWR--AVRSDIQMIFQDplASLNP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTV----KEHLELY------AAVKGLRKE--DAVVAISRLVNALKlHDQLNVQVQNLvaGATRKLcfvlsILgnSPVLI 1442
Cdd:PRK15079 114 RMTIgeiiAEPLRTYhpklsrQEVKDRVKAmmLKVGLLPNLINRYP-HEFSGGQCQRI--GIARAL-----IL--EPKLI 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1443 L-DEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGR 1497
Cdd:PRK15079 184 IcDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGH 239
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
480-646 |
1.01e-06 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 53.96 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYKGKsgKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL---YVPTAGSVTVYNK-NLSDMQdlKEIR 555
Cdd:TIGR00956 62 FRKLKKFRDTK--TFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNtdgFHIGVEGVITYDGiTPEEIK--KHYR 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 556 KAIGVCPQHNVQFDALTVKENLTLFAKIKGilPQD-----VEQEVQQILSELDMQ----------NIRDDLAEHLSEGQK 620
Cdd:TIGR00956 138 GDVVYNAETDVHFPHLTVGETLDFAARCKT--PQNrpdgvSREEYAKHIADVYMAtyglshtrntKVGNDFVRGVSGGER 215
|
170 180
....*....|....*....|....*.
gi 568976233 621 RKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:TIGR00956 216 KRVSIAEASLGGAKIQCWDNATRGLD 241
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1302-1502 |
1.11e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 51.91 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSA-----------------------VGHQGD 1358
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGdfsklqgirklvgivfqnpetqfVGRTVE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1359 SRAEFGycpQENGLWPNLTVKEHLELYAAVKGLRKedavvaisrlvnaLKLHDQlnvqvQNLVAGATRklCFVLS-ILGN 1437
Cdd:PRK13644 97 EDLAFG---PENLCLPPIEIRKRVDRALAEIGLEK-------------YRHRSP-----KTLSGGQGQ--CVALAgILTM 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568976233 1438 SP-VLILDEPSTGLDVSGKHQVWQAIQavvKDNEKG--VLLSTHDLAEAEAlCDRAAIMVSGRLRCIG 1502
Cdd:PRK13644 154 EPeCLIFDEVTSMLDPDSGIAVLERIK---KLHEKGktIVYITHNLEELHD-ADRIIVMDRGKIVLEG 217
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
467-691 |
1.46e-06 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 53.05 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 467 PVDPEYQGKEAIRIRNIKKEYKGKSGKVKALKglfLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLs 546
Cdd:PRK10522 312 PRPQAFPDWQTLELRNVTFAYQDNGFSVGPIN---LTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPV- 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 547 DMQDLKEIRKaigvcpqhnvQFDAltVKENLTLFAKIKGILPQDVEQE-VQQILSELDMQNiRDDLAEH------LSEGQ 619
Cdd:PRK10522 388 TAEQPEDYRK----------LFSA--VFTDFHLFDQLLGPEGKPANPAlVEKWLERLKMAH-KLELEDGrisnlkLSKGQ 454
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 620 KRKLTFGIATVGDPQILLLDEPTVGLDP-FSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGAL 691
Cdd:PRK10522 455 KKRLALLLALAEERDILLLDEWAADQDPhFRREFYQVLLPLLQEMGKTIFAISHDDHYFIHADRLLEMRNGQL 527
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
1302-1510 |
1.79e-06 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 51.83 E-value: 1.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKP----TA-----GQVELKRLSSA-----VGHqgdsraEFGYCP 1367
Cdd:COG4170 22 AVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDnwhvTAdrfrwNGIDLLKLSPRerrkiIGR------EIAMIF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1368 QE--NGLWPNLTVKEHLE----------LYAAVKGLRKEDAVVAISRLvnALKLHDQ-LNVQVQNLVAGATRKLCFVLSI 1434
Cdd:COG4170 96 QEpsSCLDPSAKIGDQLIeaipswtfkgKWWQRFKWRKKRAIELLHRV--GIKDHKDiMNSYPHELTEGECQKVMIAMAI 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1435 LGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRK 1510
Cdd:COG4170 174 ANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKS 249
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
512-659 |
1.98e-06 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 52.65 E-value: 1.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 512 ILGHSGAGKSSLLNILSGLYVPTAGSVtVYNKNL--SDM-QDlkeirkaigvcPQHNVQ---FD--ALTVKEnLTLFAKI 583
Cdd:PRK11147 34 LVGRNGAGKSTLMKILNGEVLLDDGRI-IYEQDLivARLqQD-----------PPRNVEgtvYDfvAEGIEE-QAEYLKR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 584 KGILPQDVEQE--------VQQILSELDMQN-------IRDDLAE----------HLSEGQKRKLTFGIATVGDPQILLL 638
Cdd:PRK11147 101 YHDISHLVETDpseknlneLAKLQEQLDHHNlwqlenrINEVLAQlgldpdaalsSLSGGWLRKAALGRALVSNPDVLLL 180
|
170 180
....*....|....*....|.
gi 568976233 639 DEPTVGLDPFSRQRIWGFLKE 659
Cdd:PRK11147 181 DEPTNHLDIETIEWLEGFLKT 201
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
479-531 |
2.09e-06 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 52.48 E-value: 2.09e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 568976233 479 RIRNIKKEYKGksgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY 531
Cdd:NF040905 3 EMRGITKTFPG----VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVY 51
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
1302-1498 |
2.27e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 51.39 E-value: 2.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSavGHQGDSRAEFGYCPQ------------- 1368
Cdd:PRK13631 41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYI--GDKKNNHELITNPYSkkiknfkelrrrv 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1369 -------ENGLWPNlTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQ-LNVQVQNLVAGATRKLCfVLSILGNSP- 1439
Cdd:PRK13631 119 smvfqfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDSyLERSPFGLSGGQKRRVA-IAGILAIQPe 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 1440 VLILDEPSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK13631 197 ILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVADEVIVMDKGKI 254
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1296-1458 |
2.39e-06 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 50.94 E-value: 2.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1296 RRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlssavGHQ---GDsraeFGYCPQE--- 1369
Cdd:PRK15112 22 RRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLID------DHPlhfGD----YSYRSQRirm 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1370 ------NGLWPNLTVKEHLE----LYAAVKGLRKEDAVVAISRLVNALKlhDQLNVQVQNLVAGATRKLCFVLSILGNSP 1439
Cdd:PRK15112 92 ifqdpsTSLNPRQRISQILDfplrLNTDLEPEQREKQIIETLRQVGLLP--DHASYYPHMLAPGQKQRLGLARALILRPK 169
|
170
....*....|....*....
gi 568976233 1440 VLILDEPSTGLDVSGKHQV 1458
Cdd:PRK15112 170 VIIADEALASLDMSMRSQL 188
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
478-689 |
2.66e-06 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 52.13 E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYkgksGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVY-------NKNLSDMQd 550
Cdd:TIGR02633 2 LEMKGIVKTF----GGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTWDGEIYwsgsplkASNIRDTE- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 551 lkeiRKAIGVCPQHNVQFDALTVKENLTLFAKI--KGILPQDVE--QEVQQILSELDMQNIRDDLA-EHLSEGQKRKLTF 625
Cdd:TIGR02633 77 ----RAGIVIIHQELTLVPELSVAENIFLGNEItlPGGRMAYNAmyLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEI 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 626 GIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHV-ILFSTQFMDEADILADRKVLIANG 689
Cdd:TIGR02633 153 AKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVaCVYISHKLNEVKAVCDTICVIRDG 217
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1300-1543 |
2.95e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 52.22 E-value: 2.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1300 NMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKpTAGQVELKRLS-SAVGHQgDSRAEFGYCPQENGLWPNlTV 1378
Cdd:TIGR01271 1232 RAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSwNSVTLQ-TWRKAFGVIPQKVFIFSG-TF 1308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLELYA--AVKGLRKEDAVVAISRLVNalKLHDQLNVQVQN----LVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:TIGR01271 1309 RKNLDPYEqwSDEEIWKVAEEVGLKSVIE--QFPDKLDFVLVDggyvLSNGHKQLMCLARSILSKAKILLLDEPSAHLDP 1386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1453 SgkhqVWQAIQAVVKD--NEKGVLLSTHDLaEAEALCDRAAIMVSGRLRCIGPIQHLkrkfgqdyvleLRVKDVSQEPLV 1530
Cdd:TIGR01271 1387 V----TLQIIRKTLKQsfSNCTVILSEHRV-EALLECQQFLVIEGSSVKQYDSIQKL-----------LNETSLFKQAMS 1450
|
250
....*....|...
gi 568976233 1531 HREILKLFPQAAR 1543
Cdd:TIGR01271 1451 AADRLKLFPLHRR 1463
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1302-1498 |
3.26e-06 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 50.26 E-value: 3.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlSSAVGHQGDS---RAEFGYCPQENGLWPNLTV 1378
Cdd:PRK11614 20 ALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFD--GKDITDWQTAkimREAVAIVPEGRRVFSRMTV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHLelyaAVKGL--RKEDAVVAISRLVNAL-KLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGK 1455
Cdd:PRK11614 98 EENL----AMGGFfaERDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIII 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 1456 HQVWQAIQAVvkdNEKG--VLLSTHDLAEAEALCDRAAIMVSGRL 1498
Cdd:PRK11614 174 QQIFDTIEQL---REQGmtIFLVEQNANQALKLADRGYVLENGHV 215
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
506-653 |
3.31e-06 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 51.73 E-value: 3.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 506 ESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTV------------------YNKNLSDmqdlKEIRKAigvcpqHNVQ 567
Cdd:PRK13409 98 EGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEEepswdevlkrfrgtelqnYFKKLYN----GEIKVV------HKPQ 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 568 F-DAL------TVKEnltLFAKI--KGILpqdveqevQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLL 638
Cdd:PRK13409 168 YvDLIpkvfkgKVRE---LLKKVdeRGKL--------DEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFF 236
|
170
....*....|....*
gi 568976233 639 DEPTVGLDpfSRQRI 653
Cdd:PRK13409 237 DEPTSYLD--IRQRL 249
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
443-702 |
3.89e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 51.90 E-value: 3.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 443 KTANRNKVIERDLDPELPSDEYFEPVDPEYQGKEAIRIRNIKKEYKGKSGKvKALKGLFLDIYESQITAILGHSGAGKSS 522
Cdd:PLN03232 580 QVVNANVSLQRIEELLLSEERILAQNPPLQPGAPAISIKNGYFSWDSKTSK-PTLSDINLEIPVGSLVAIVGGTGEGKTS 658
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 523 LLNILSGlyvptagsvtvynkNLSDMQDLK-EIRKAIGVCPQHNVQFDAlTVKENLtLFAkikgilpQDVEQE------- 594
Cdd:PLN03232 659 LISAMLG--------------ELSHAETSSvVIRGSVAYVPQVSWIFNA-TVRENI-LFG-------SDFESErywraid 715
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 595 VQQILSELDMQNIRD--DLAE---HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP-FSRQRIWGFLKER-RADHVIL 667
Cdd:PLN03232 716 VTALQHDLDLLPGRDltEIGErgvNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAhVAHQVFDSCMKDElKGKTRVL 795
|
250 260 270
....*....|....*....|....*....|....*..
gi 568976233 668 FSTQ--FMDeadiLADRKVLIANGALKCTGSSVFLKR 702
Cdd:PLN03232 796 VTNQlhFLP----LMDRIILVSEGMIKEEGTFAELSK 828
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
478-646 |
5.16e-06 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 51.22 E-value: 5.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 478 IRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKS----SLLNILSGLYVPTAGSVTVYNKNLSDM--QDL 551
Cdd:COG4172 7 LSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLseREL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 552 KEIR-KAIGVC---------PQHNV--QfdaltVKENLTLfakIKGILPQDVEQEVQQILSELDMQNIRDDLAE--H-LS 616
Cdd:COG4172 87 RRIRgNRIAMIfqepmtslnPLHTIgkQ-----IAEVLRL---HRGLSGAAARARALELLERVGIPDPERRLDAypHqLS 158
|
170 180 190
....*....|....*....|....*....|
gi 568976233 617 EGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:COG4172 159 GGQRQRVMIAMALANEPDLLIADEPTTALD 188
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1302-1502 |
6.01e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 50.12 E-value: 6.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRL-SSAVGHQGD---SRAEFGYCPQ--ENGLWPN 1375
Cdd:PRK13643 21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIvVSSTSKQKEikpVRKKVGVVFQfpESQLFEE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 lTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSP-VLILDEPSTGLDVSG 1454
Cdd:PRK13643 101 -TVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPeVLVLDEPTAGLDPKA 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568976233 1455 KHQVWQAIQAVVKDNEKgVLLSTHDLAEAEALCDRAAIMVSGRLRCIG 1502
Cdd:PRK13643 180 RIEMMQLFESIHQSGQT-VVLVTHLMDDVADYADYVYLLEKGHIISCG 226
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
1298-1483 |
8.92e-06 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 50.61 E-value: 8.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1298 TRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGitKPTAGQVELKRLSSAVGHQGDSRAEF-GYCPQENGLWPNL 1376
Cdd:PLN03140 891 DRLQLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAG--RKTGGYIEGDIRISGFPKKQETFARIsGYCEQNDIHSPQV 968
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLeLYAAVKGLRKE----------DAVVAISRLVNalkLHDQLnVQVQNLVAGAT---RKLCFVLSILGNSPVLIL 1443
Cdd:PLN03140 969 TVRESL-IYSAFLRLPKEvskeekmmfvDEVMELVELDN---LKDAI-VGLPGVTGLSTeqrKRLTIAVELVANPSIIFM 1043
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 568976233 1444 DEPSTGLDVSGKHQVWQAIQAVVkDNEKGVLLSTH----DLAEA 1483
Cdd:PLN03140 1044 DEPTSGLDARAAAIVMRTVRNTV-DTGRTVVCTIHqpsiDIFEA 1086
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1302-1540 |
9.11e-06 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 50.31 E-value: 9.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITkPT---------AGQvELKrlssaVGHQGDS-RAEFGYCPQENG 1371
Cdd:PRK13549 20 ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHgtyegeiifEGE-ELQ-----ASNIRDTeRAGIAIIHQELA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1372 LWPNLTVKEHLELYAAV--KGLRKEDAVVA-ISRLVNALKLHDQLNVQVQNL---------VAGATRKlcfvlsilgNSP 1439
Cdd:PRK13549 93 LVKELSVLENIFLGNEItpGGIMDYDAMYLrAQKLLAQLKLDINPATPVGNLglgqqqlveIAKALNK---------QAR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1440 VLILDEPSTGLDVSGKhqvwQAIQAVVKD-NEKGV--LLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLkrkfGQDYV 1516
Cdd:PRK13549 164 LLILDEPTASLTESET----AVLLDIIRDlKAHGIacIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGM----TEDDI 235
|
250 260
....*....|....*....|....
gi 568976233 1517 LELrvkdvsqepLVHREILKLFPQ 1540
Cdd:PRK13549 236 ITM---------MVGRELTALYPR 250
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
506-653 |
9.30e-06 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 48.90 E-value: 9.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 506 ESQITAILGHSGAGKSSLLNILSGLYVPTAGSVT--------VYNKNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKenl 577
Cdd:cd03236 25 EGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDdppdwdeiLDEFRGSELQNYFTKLLEGDVKVIVKPQYVDLIPK--- 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 578 TLFAKIKGILPQDVEQEVQQILSE-LDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDpfSRQRI 653
Cdd:cd03236 102 AVKGKVGELLKKKDERGKLDELVDqLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLD--IKQRL 176
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1305-1346 |
1.04e-05 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 50.12 E-value: 1.04e-05
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL 1346
Cdd:PRK11819 342 DLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI 383
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
492-646 |
1.15e-05 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 48.87 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 492 GKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSG--LYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFD 569
Cdd:CHL00131 18 NENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGESILDLEPEERAHLGIFLAFQYPIEIP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 570 ALTVKENLTLFAKIKGILPQDVEQE-------VQQILSELDMQN--IRDDLAEHLSEGQKRK---LTFGIAtvgDPQILL 637
Cdd:CHL00131 98 GVSNADFLRLAYNSKRKFQGLPELDplefleiINEKLKLVGMDPsfLSRNVNEGFSGGEKKRneiLQMALL---DSELAI 174
|
....*....
gi 568976233 638 LDEPTVGLD 646
Cdd:CHL00131 175 LDETDSGLD 183
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
490-646 |
1.28e-05 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 50.23 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 490 KSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPT---AGSVTvYNKnlsdmQDLKEI--RKAIGVCPQH 564
Cdd:PLN03140 174 KKTKLTILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSlkvSGEIT-YNG-----YRLNEFvpRKTSAYISQN 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 565 NVQFDALTVKENLTLFAKIKG-------------------ILPqdvEQEVQQILSELDMQNIR----------------- 608
Cdd:PLN03140 248 DVHVGVMTVKETLDFSARCQGvgtrydllselarrekdagIFP---EAEVDLFMKATAMEGVKsslitdytlkilgldic 324
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 568976233 609 ------DDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PLN03140 325 kdtivgDEMIRGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLD 368
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
1303-1461 |
1.47e-05 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 48.70 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVElkrlssavgHQGdsraEFGYCPQENGLWPNlTVKEHL 1382
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIK---------HSG----RISFSSQFSWIMPG-TIKENI 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 ELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQ----NLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQV 1458
Cdd:cd03291 119 IFGVSYDEYRYKSVVKACQLEEDITKFPEKDNTVLGeggiTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEI 198
|
...
gi 568976233 1459 WQA 1461
Cdd:cd03291 199 FES 201
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1302-1496 |
1.83e-05 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 49.23 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELkrLSSAVGHQG--DSR-AEFGYCPQENGLWPNLTV 1378
Cdd:PRK10762 19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILY--LGKEVTFNGpkSSQeAGIGIIHQELNLIPQLTI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1379 KEHL----------------ELYAAVKGLRKEDAVVAIS-RLVNALKLHDQLNVQVQNlvagatrklcfVLSIlgNSPVL 1441
Cdd:PRK10762 97 AENIflgrefvnrfgridwkKMYAEADKLLARLNLRFSSdKLVGELSIGEQQMVEIAK-----------VLSF--ESKVI 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1442 ILDEPSTGLDVSGKHQVWQAIQAvVKDNEKGVLLSTHDLAEAEALCDRAAIMVSG 1496
Cdd:PRK10762 164 IMDEPTDALTDTETESLFRVIRE-LKSQGRGIVYISHRLKEIFEICDDVTVFRDG 217
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
481-646 |
1.89e-05 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 48.81 E-value: 1.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 481 RNIKKEYKGKSG------KVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNL--SDMQDLK 552
Cdd:PRK11308 9 IDLKKHYPVKRGlfkperLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLlkADPEAQK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 553 EIRKAIGVCPQHnvQFDALTVKEnltlfaKIKGILPQ--------DVEQEVQQILSELDMQNIRddlAEH-------LSE 617
Cdd:PRK11308 89 LLRQKIQIVFQN--PYGSLNPRK------KVGQILEEpllintslSAAERREKALAMMAKVGLR---PEHydryphmFSG 157
|
170 180
....*....|....*....|....*....
gi 568976233 618 GQKRKLTFGIATVGDPQILLLDEPTVGLD 646
Cdd:PRK11308 158 GQRQRIAIARALMLDPDVVVADEPVSALD 186
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1317-1383 |
2.08e-05 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 49.35 E-value: 2.08e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568976233 1317 GLLGPDGAGKSSSIRMIAGITKPTAGQVelkRLSsavghQGdsrAEFGYCPQENGLWPNLTVKEHLE 1383
Cdd:PRK11819 37 GVLGLNGAGKSTLLRIMAGVDKEFEGEA---RPA-----PG---IKVGYLPQEPQLDPEKTVRENVE 92
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
451-640 |
2.28e-05 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 49.03 E-value: 2.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 451 IERDLDPElPSDEYFEPVDPEYQGKEAIRIRNIKKEYKGKSGKvkalkGLF------LDIYESQITAILGHSGAGKSSLL 524
Cdd:COG4615 302 LELALAAA-EPAAADAAAPPAPADFQTLELRGVTYRYPGEDGD-----EGFtlgpidLTIRRGELVFIVGGNGSGKSTLA 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 525 NILSGLYVPTAGSVTVyNKNLSDMQDLKEIRKAIGV--CPQHnvqfdaltvkenltLFAKIKGILPQDVEQEVQQILSEL 602
Cdd:COG4615 376 KLLTGLYRPESGEILL-DGQPVTADNREAYRQLFSAvfSDFH--------------LFDRLLGLDGEADPARARELLERL 440
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 568976233 603 DMQN---IRDD----LAehLSEGQKRKLTFGIATVGDPQILLLDE 640
Cdd:COG4615 441 ELDHkvsVEDGrfstTD--LSQGQRKRLALLVALLEDRPILVFDE 483
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
465-682 |
2.55e-05 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 49.01 E-value: 2.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 465 FE--PVDPEYQGKEAIRIRNIKKEYKGKSGKVKAlkGlflDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVyn 542
Cdd:COG1245 327 FEvhAPRREKEEETLVEYPDLTKSYGGFSLEVEG--G---EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDE-- 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 543 knlsdmqDLKeirkaIGVCPQHNVQFDALTVKENltLFAKIKGILPQDVEQEvqQILSELDMQNIRDDLAEHLSEGQKRK 622
Cdd:COG1245 400 -------DLK-----ISYKPQYISPDYDGTVEEF--LRSANTDDFGSSYYKT--EIIKPLGLEKLLDKNVKDLSGGELQR 463
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 623 LTFGIATVGDPQILLLDEPTVGLDpfSRQR------IWGFLKERRA-----DHVILFstqfmdeADILADR 682
Cdd:COG1245 464 VAIAACLSRDADLYLLDEPSAHLD--VEQRlavakaIRRFAENRGKtamvvDHDIYL-------IDYISDR 525
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
509-646 |
2.57e-05 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 47.62 E-value: 2.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 509 ITAILGHSGAGKSSLLNILSGLyVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFdALTVKENLTLFakikgiLP 588
Cdd:PRK03695 24 ILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELARHRAYLSQQQTPPF-AMPVFQYLTLH------QP 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 589 -QDVEQEVQQILSEL-DMQNIRDDLAEHLS-----EGQKRKLTFGIATV---GDP--QILLLDEPTVGLD 646
Cdd:PRK03695 96 dKTRTEAVASALNEVaEALGLDDKLGRSVNqlsggEWQRVRLAAVVLQVwpdINPagQLLLLDEPMNSLD 165
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1302-1497 |
3.63e-05 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 48.53 E-value: 3.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITkPTAGQVEL--KRLSSAVGHQ----------------------- 1356
Cdd:COG4172 301 AVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFdgQDLDGLSRRAlrplrrrmqvvfqdpfgslsprm 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1357 --GDSRAEfgycpqenGL---WPNLTVKEHLELYAAV---KGLRKEDAV-------------VAISRlvnALKLHDQLnv 1415
Cdd:COG4172 380 tvGQIIAE--------GLrvhGPGLSAAERRARVAEAleeVGLDPAARHryphefsggqrqrIAIAR---ALILEPKL-- 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1416 qvqnlvagatrklcfvlsilgnspvLILDEPSTGLDVSGKHQV---WQAIQAvvkdnEKGV--LLSTHDLAEAEALCDRA 1490
Cdd:COG4172 447 -------------------------LVLDEPTSALDVSVQAQIldlLRDLQR-----EHGLayLFISHDLAVVRALAHRV 496
|
....*..
gi 568976233 1491 AIMVSGR 1497
Cdd:COG4172 497 MVMKDGK 503
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1304-1451 |
3.66e-05 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 48.35 E-value: 3.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1304 RNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVelkrlssavghQGDSRAEFGYCPQENGLW--PNLTVKEH 1381
Cdd:PRK15064 336 KNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV-----------KWSENANIGYYAQDHAYDfeNDLTLFDW 404
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1382 LELYAAVKGlrKEDAVVAI-SRLvnaLKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLD 1451
Cdd:PRK15064 405 MSQWRQEGD--DEQAVRGTlGRL---LFSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMD 470
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1296-1519 |
3.72e-05 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 48.16 E-value: 3.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1296 RRT--RNMAVRNVSFCVNKGEILGLLGPDGAGKSssirmiagitkpTAGqVELKRLSSAVG---------HQGDSRAEFG 1364
Cdd:PRK15134 293 KRTvdHNVVVKNISFTLRPGETLGLVGESGSGKS------------TTG-LALLRLINSQGeiwfdgqplHNLNRRQLLP 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1365 YCPQ--------ENGLWPNLTV----KEHLEL-YAAVKGLRKEDAVVAISRLVNalkLHDQLNVQVQNLVAGATRKLCFV 1431
Cdd:PRK15134 360 VRHRiqvvfqdpNSSLNPRLNVlqiiEEGLRVhQPTLSAAQREQQVIAVMEEVG---LDPETRHRYPAEFSGGQRQRIAI 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1432 LSILGNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRK 1510
Cdd:PRK15134 437 ARALILKPsLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAA 516
|
....*....
gi 568976233 1511 FGQDYVLEL 1519
Cdd:PRK15134 517 PQQEYTRQL 525
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
1267-1483 |
4.97e-05 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 46.49 E-value: 4.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1267 STPNLDEKPVIIASCLHKEYAGQKKHccsrrtrnmAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITK--PTAGQV 1344
Cdd:COG2401 19 SVLDLSERVAIVLEAFGVELRVVERY---------VLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1345 ELkrlssavghqgdsraefgycpQENGLWPNLTVKEHLelyaavkgLRKEDAVVAISRLvNALKLHDQLNV--QVQNLVA 1422
Cdd:COG2401 90 DV---------------------PDNQFGREASLIDAI--------GRKGDFKDAVELL-NAVGLSDAVLWlrRFKELST 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 1423 GATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTH--DLAEA 1483
Cdd:COG2401 140 GQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHhyDVIDD 202
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1303-1478 |
6.80e-05 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 46.17 E-value: 6.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAG--ITKPTAGQVELKRlSSAVGHQGDSRAEFG------YcPQEnglWP 1374
Cdd:CHL00131 23 LKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKG-ESILDLEPEERAHLGiflafqY-PIE---IP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1375 NLTVKEHLEL-YAAVK---GLRKEDAVVAISRLVNALKLHDQ----LNVQVQNLVAGATRKLCFVLS-ILGNSPVLILDE 1445
Cdd:CHL00131 98 GVSNADFLRLaYNSKRkfqGLPELDPLEFLEIINEKLKLVGMdpsfLSRNVNEGFSGGEKKRNEILQmALLDSELAILDE 177
|
170 180 190
....*....|....*....|....*....|...
gi 568976233 1446 PSTGLDVSGKHQVWQAIQaVVKDNEKGVLLSTH 1478
Cdd:CHL00131 178 TDSGLDIDALKIIAEGIN-KLMTSENSIILITH 209
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
508-692 |
8.91e-05 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 47.23 E-value: 8.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 508 QITAILGHSGAGKSSLLNILSGLYvPTA--GSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFD---ALTVKENLTL--- 579
Cdd:PRK13549 289 EILGIAGLVGAGRTELVQCLFGAY-PGRweGEIFIDGKPVKIRNPQQAIAQGIAMVPEDRKRDGivpVMGVGKNITLaal 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 580 --FAKIKGIlpqDVEQEVQQILSELDMQNIRD---DLA-EHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRI 653
Cdd:PRK13549 368 drFTGGSRI---DDAAELKTILESIQRLKVKTaspELAiARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEI 444
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 568976233 654 WGFLKE--RRADHVILFSTQfMDEADILADRKVLIANGALK 692
Cdd:PRK13549 445 YKLINQlvQQGVAIIVISSE-LPEVLGLSDRVLVMHEGKLK 484
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
499-689 |
9.61e-05 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 47.01 E-value: 9.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 499 GLFLDIYESQITAILGHSGAGKS-SLLNILSGLYVP----TAGSVTVYNKNL--SDMQDLKEIR----------KAIGVC 561
Cdd:PRK15134 27 DVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLlhASEQTLRGVRgnkiamifqePMVSLN 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 562 PQHNVQfdaLTVKENLTLFAKIKGilpqdvEQEVQQILSELDMQNIRD------DLAEHLSEGQKRKLTFGIATVGDPQI 635
Cdd:PRK15134 107 PLHTLE---KQLYEVLSLHRGMRR------EAARGEILNCLDRVGIRQaakrltDYPHQLSGGERQRVMIAMALLTRPEL 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 636 LLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMDEADILADRKVLIANG 689
Cdd:PRK15134 178 LIADEPTTALDVSVQAQILQLLRElqQELNMGLLFITHNLSIVRKLADRVAVMQNG 233
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
1303-1499 |
1.06e-04 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 45.80 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITK-----PTAGQVE------------LKRLSSAVGHqgdsraefgY 1365
Cdd:PRK14258 23 LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNElesevRVEGRVEffnqniyerrvnLNRLRRQVSM---------V 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1366 CPQENgLWPnLTVKEHLELYAAVKGLRKE---DAVVAISrlVNALKLHDQLNVQVQ----NLVAGATRKLCFVLSILGNS 1438
Cdd:PRK14258 94 HPKPN-LFP-MSVYDNVAYGVKIVGWRPKleiDDIVESA--LKDADLWDEIKHKIHksalDLSGGQQQRLCIARALAVKP 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568976233 1439 PVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLR 1499
Cdd:PRK14258 170 KVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENR 230
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
461-666 |
1.09e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 47.25 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 461 SDEYFEPVDPEYQ-----GKEAIRIRNikKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTA 535
Cdd:TIGR00957 615 SHEELEPDSIERRtikpgEGNSITVHN--ATFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVE 692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 536 GSVTvynknlsdmqdlkeIRKAIGVCPQHN-VQFDALtvKENLtLFAKikgILPQDVEQEVQQ---ILSELDM--QNIRD 609
Cdd:TIGR00957 693 GHVH--------------MKGSVAYVPQQAwIQNDSL--RENI-LFGK---ALNEKYYQQVLEacaLLPDLEIlpSGDRT 752
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 610 DLAE---HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWgflkerraDHVI 666
Cdd:TIGR00957 753 EIGEkgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIF--------EHVI 804
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1303-1461 |
1.81e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 46.44 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1303 VRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVElkrlssavgHQGdsraEFGYCPQENGLWPNlTVKEHL 1382
Cdd:TIGR01271 442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIK---------HSG----RISFSPQTSWIMPG-TIKDNI 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1383 elyaaVKGLRKEDavVAISRLVNALKLHDQLNVQVQ-----------NLVAGATRKLCFVLSILGNSPVLILDEPSTGLD 1451
Cdd:TIGR01271 508 -----IFGLSYDE--YRYTSVIKACQLEEDIALFPEkdktvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
|
170
....*....|
gi 568976233 1452 VSGKHQVWQA 1461
Cdd:TIGR01271 581 VVTEKEIFES 590
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
493-691 |
2.26e-04 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 45.67 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 493 KVKALKG------LFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQhNV 566
Cdd:PRK11288 259 RLDGLKGpglrepISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGIMLCPE-DR 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 567 QFDAL----TVKENLTL-----FAKIKGILPQDVEQEV--QQILSeldmQNI----RDDLAEHLSEGQKRKLTFGIATVG 631
Cdd:PRK11288 338 KAEGIipvhSVADNINIsarrhHLRAGCLINNRWEAENadRFIRS----LNIktpsREQLIMNLSGGNQQKAILGRWLSE 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 632 DPQILLLDEPTVGLDPFSRQRIWGFLKE--RRADHVILFSTQFMdEADILADRKVLIANGAL 691
Cdd:PRK11288 414 DMKVILLDEPTRGIDVGAKHEIYNVIYElaAQGVAVLFVSSDLP-EVLGVADRIVVMREGRI 474
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
1302-1510 |
2.40e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 45.01 E-value: 2.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQV--------------ELKRLSSAVG-------HQ-GDS 1359
Cdd:PRK13634 22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVtigervitagkknkKLKPLRKKVGivfqfpeHQlFEE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1360 RAE----FGycPQenglwpNLTVKEHlelyaavKGLRKEDAVVAISRLVnalklHDQLNVQVQNLVAGATRKLCfVLSIL 1435
Cdd:PRK13634 102 TVEkdicFG--PM------NFGVSEE-------DAKQKAREMIELVGLP-----EELLARSPFELSGGQMRRVA-IAGVL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1436 GNSP-VLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRK 1510
Cdd:PRK13634 161 AMEPeVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFAD 236
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
497-647 |
3.28e-04 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 43.79 E-value: 3.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYV--PTAGSVTVYNKNLSdmqdlkeirkaigvcpqhnvqfdaltvk 574
Cdd:COG2401 46 LRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPDNQFG---------------------------- 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 575 ENLTLfakIKGILPQDVEQEVQQILSEL---DMQNIRDDLAEhLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:COG2401 98 REASL---IDAIGRKGDFKDAVELLNAVglsDAVLWLRRFKE-LSTGQKFRFRLALLLAERPKLLVIDEFCSHLDR 169
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
465-682 |
3.34e-04 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 45.18 E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 465 FE--PVDPEYQGKEAIRIRNIKKEYKGKSGKVKAlkGlflDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTvyn 542
Cdd:PRK13409 326 FEerPPRDESERETLVEYPDLTKKLGDFSLEVEG--G---EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVD--- 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 543 knlsdmQDLKeirkaIGVCPQH-NVQFDaLTVKENLtlfAKIKGILpqDVEQEVQQILSELDMQNIRDDLAEHLSEGQKR 621
Cdd:PRK13409 398 ------PELK-----ISYKPQYiKPDYD-GTVEDLL---RSITDDL--GSSYYKSEIIKPLQLERLLDKNVKDLSGGELQ 460
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568976233 622 KLTFGIATVGDPQILLLDEPTVGLDpfSRQR------IWGFLKERRA-----DHVILFstqfmdeADILADR 682
Cdd:PRK13409 461 RVAIAACLSRDADLYLLDEPSAHLD--VEQRlavakaIRRIAEEREAtalvvDHDIYM-------IDYISDR 523
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
497-646 |
4.51e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 45.32 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMqDLKEIRKAIGVCPQHNVQFDAlTVKEN 576
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKI-GLHDLRFKITIIPQDPVLFSG-SLRMN 1379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 577 LTLFAkikgilpQDVEQEVQQILSELDMQNIRDDL-----------AEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGL 645
Cdd:TIGR00957 1380 LDPFS-------QYSDEEVWWALELAHLKTFVSALpdkldhecaegGENLSVGQRQLVCLARALLRKTKILVLDEATAAV 1452
|
.
gi 568976233 646 D 646
Cdd:TIGR00957 1453 D 1453
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
1296-1452 |
5.71e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 44.94 E-value: 5.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1296 RRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPN 1375
Cdd:TIGR00957 1295 REDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIPQDPVLFSG 1374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1376 lTVKEHLELYAAVKglrKEDAVVAIS-----RLVNALKlhDQLNVQV----QNLVAGATRKLCFVLSILGNSPVLILDEP 1446
Cdd:TIGR00957 1375 -SLRMNLDPFSQYS---DEEVWWALElahlkTFVSALP--DKLDHECaeggENLSVGQRQLVCLARALLRKTKILVLDEA 1448
|
....*.
gi 568976233 1447 STGLDV 1452
Cdd:TIGR00957 1449 TAAVDL 1454
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
1305-1478 |
5.95e-04 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 44.71 E-value: 5.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1305 NVSFCVNKGEILGLLGPDGAGKSSSIRMIAGitKPTAGQVEL-KRLSSavGHQGDSRAE--FGYCPQENGLWPNLTVKEH 1381
Cdd:TIGR00956 781 NVDGWVKPGTLTALMGASGAGKTTLLNVLAE--RVTTGVITGgDRLVN--GRPLDSSFQrsIGYVQQQDLHLPTSTVRES 856
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAvkgLR---------KEDAVVAISRLVNALKLHDQ--------LNVQvqnlvagaTRKLcfvLSI---LGNSPVL 1441
Cdd:TIGR00956 857 LRFSAY---LRqpksvskseKMEYVEEVIKLLEMESYADAvvgvpgegLNVE--------QRKR---LTIgveLVAKPKL 922
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 568976233 1442 I--LDEPSTGLDvsgKHQVWQAIQAVVK--DNEKGVLLSTH 1478
Cdd:TIGR00956 923 LlfLDEPTSGLD---SQTAWSICKLMRKlaDHGQAILCTIH 960
|
|
| YjeQ_EngC |
cd01854 |
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ... |
448-529 |
6.50e-04 |
|
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.
Pssm-ID: 206747 [Multi-domain] Cd Length: 211 Bit Score: 42.77 E-value: 6.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 448 NKVierDLDPELPSDEYFEPVdpEYQGKEAIRIRNIKKEykgksgKVKALKGLFLDiyesQITAILGHSGAGKSSLLNIL 527
Cdd:cd01854 41 NKA---DLVDDEELEELLEIY--EKLGYPVLAVSAKTGE------GLDELRELLKG----KTSVLVGQSGVGKSTLLNAL 105
|
..
gi 568976233 528 SG 529
Cdd:cd01854 106 LP 107
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
1302-1480 |
6.81e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 43.54 E-value: 6.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFgycpqengLWPNLTVKEH 1381
Cdd:PRK13651 22 ALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEKV--------LEKLVIQKTR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1382 LELYAAVKGLRKEDAVV--------------------AISRLVN---ALKL-----------HDQLNVQVQNLVAGATRK 1427
Cdd:PRK13651 94 FKKIKKIKEIRRRVGVVfqfaeyqlfeqtiekdiifgPVSMGVSkeeAKKRaakyielvgldESYLQRSPFELSGGQKRR 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 1428 LCFVlSILGNSP-VLILDEPSTGLDVSGKHQVWQaIQAVVKDNEKGVLLSTHDL 1480
Cdd:PRK13651 174 VALA-GILAMEPdFLVFDEPTAGLDPQGVKEILE-IFDNLNKQGKTIILVTHDL 225
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1302-1346 |
7.94e-04 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 43.68 E-value: 7.94e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVEL 1346
Cdd:PRK11650 19 VIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWI 63
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
1297-1472 |
8.94e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 44.20 E-value: 8.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1297 RTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGitkptagqvelkRLSSAVGHQGDSRAEFGYCPQENGLWpNL 1376
Cdd:PLN03232 627 KTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLG------------ELSHAETSSVVIRGSVAYVPQVSWIF-NA 693
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1377 TVKEHLELYAAVKGLRKEDA--VVAISRLVNALKLHDQLNVQVQ--NLVAGATRKLCFVLSILGNSPVLILDEPSTGLDV 1452
Cdd:PLN03232 694 TVRENILFGSDFESERYWRAidVTALQHDLDLLPGRDLTEIGERgvNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDA 773
|
170 180
....*....|....*....|
gi 568976233 1453 SGKHQVWqaiQAVVKDNEKG 1472
Cdd:PLN03232 774 HVAHQVF---DSCMKDELKG 790
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
503-689 |
1.01e-03 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 43.56 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 503 DIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEI----------RKAIGVCPQHNVQFDALT 572
Cdd:PRK10982 270 DLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAInhgfalvteeRRSTGIYAYLDIGFNSLI 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 573 vkENLTLFAKIKGILP-QDVEQEVQQILselDMQNIR----DDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:PRK10982 350 --SNIRNYKNKVGLLDnSRMKSDTQWVI---DSMRVKtpghRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDV 424
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 568976233 648 FSRQRIWGFLKE--RRADHVILFSTQfMDEADILADRKVLIANG 689
Cdd:PRK10982 425 GAKFEIYQLIAElaKKDKGIIIISSE-MPELLGITDRILVMSNG 467
|
|
| RsgA |
COG1162 |
Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis]; |
508-529 |
1.23e-03 |
|
Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440776 [Multi-domain] Cd Length: 300 Bit Score: 42.79 E-value: 1.23e-03
10 20
....*....|....*....|..
gi 568976233 508 QITAILGHSGAGKSSLLNILSG 529
Cdd:COG1162 167 KTSVLVGQSGVGKSTLINALLP 188
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
480-646 |
1.38e-03 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 42.47 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 480 IRNIKKEYKGKSgkvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGL--YVPTAGSVTVYNKNLSDMQDLKEIRKA 557
Cdd:PRK09580 4 IKDLHVSVEDKA----ILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDLLELSPEDRAGEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 558 IGVCPQHNVQFDALT----VKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEH-----LSEGQKRKLTFGIA 628
Cdd:PRK09580 80 IFMAFQYPVEIPGVSnqffLQTALNAVRSYRGQEPLDRFDFQDLMEEKIALLKMPEDLLTRsvnvgFSGGEKKRNDILQM 159
|
170
....*....|....*...
gi 568976233 629 TVGDPQILLLDEPTVGLD 646
Cdd:PRK09580 160 AVLEPELCILDESDSGLD 177
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
497-653 |
1.71e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 43.23 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 497 LKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVynknlsdmqdlkeiRKAIGVCPQHNVQFDAlTVKEN 576
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWA--------------ERSIAYVPQQAWIMNA-TVRGN 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 577 LTLFAKIKGILPQDV------EQEVQQILSELDMQnirddLAE---HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP 647
Cdd:PTZ00243 741 ILFFDEEDAARLADAvrvsqlEADLAQLGGGLETE-----IGEkgvNLSGGQKARVSLARAVYANRDVYLLDDPLSALDA 815
|
....*.
gi 568976233 648 FSRQRI 653
Cdd:PTZ00243 816 HVGERV 821
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
502-651 |
1.71e-03 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 42.69 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 502 LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTvynknlSDMQ-----DLKEIRKAIGVCPQHNvQFDALTVKEN 576
Cdd:PRK10938 24 LTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQ------SQFShitrlSFEQLQKLVSDEWQRN-NTDMLSPGED 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 577 LTlfakikGILPQDVEQE-------VQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFS 649
Cdd:PRK10938 97 DT------GRTTAEIIQDevkdparCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVAS 170
|
..
gi 568976233 650 RQ 651
Cdd:PRK10938 171 RQ 172
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
1306-1498 |
2.28e-03 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 43.04 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1306 VSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNlTVKEHLELY 1385
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQSPVLFSG-TVRFNIDPF 1333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1386 AA------VKGLRKEDAVVAISRlvNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVsgkhQVW 1459
Cdd:PLN03232 1334 SEhndadlWEALERAHIKDVIDR--NPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDV----RTD 1407
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 568976233 1460 QAIQAVVKDNEKG--VLLSTHDLaEAEALCDRAAIMVSGRL 1498
Cdd:PLN03232 1408 SLIQRTIREEFKSctMLVIAHRL-NTIIDCDKILVLSSGQV 1447
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
470-669 |
3.06e-03 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 42.01 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 470 PEYQGKEAIRIRNIKkeYKGKSgkVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQ 549
Cdd:PRK10789 308 PEGRGELDVNIRQFT--YPQTD--HPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQ 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 550 dLKEIRKAIGVCPQHNVQFDAlTVKENLTLFAkikgilPQDVEQEVQQILSeldMQNIRDDLAE--------------HL 615
Cdd:PRK10789 384 -LDSWRSRLAVVSQTPFLFSD-TVANNIALGR------PDATQQEIEHVAR---LASVHDDILRlpqgydtevgergvML 452
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568976233 616 SEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFS 669
Cdd:PRK10789 453 SGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGEGRTVIIS 506
|
|
| RsgA_GTPase |
pfam03193 |
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are ... |
506-529 |
3.16e-03 |
|
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern.
Pssm-ID: 427191 [Multi-domain] Cd Length: 174 Bit Score: 40.22 E-value: 3.16e-03
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
1302-1343 |
3.86e-03 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 41.49 E-value: 3.86e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 568976233 1302 AVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQ 1343
Cdd:PRK11308 30 ALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGE 71
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
1306-1512 |
4.50e-03 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 41.85 E-value: 4.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1306 VSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKrlssavghqgdsrAEFGYCPQEngLW-PNLTVKEHLEL 1384
Cdd:TIGR00957 657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMK-------------GSVAYVPQQ--AWiQNDSLRENILF 721
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1385 YAAVKGLRKEDAVVAISRL--VNALKLHDQLNVQVQ--NLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVS-GKHQVW 1459
Cdd:TIGR00957 722 GKALNEKYYQQVLEACALLpdLEILPSGDRTEIGEKgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHvGKHIFE 801
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568976233 1460 QAI--QAVVKDneKGVLLSTHDLAEAEALcDRAAIMVSGRLRCIGPIQHLKRKFG 1512
Cdd:TIGR00957 802 HVIgpEGVLKN--KTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDG 853
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
452-696 |
5.19e-03 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 41.65 E-value: 5.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 452 ERDLDPELPsdeyFEPVDPeyqgkeAIRIRNIKKEYKGKSGKvKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLY 531
Cdd:PLN03130 599 ERVLLPNPP----LEPGLP------AISIKNGYFSWDSKAER-PTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGEL 667
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 532 VPTAGSVTVynknlsdmqdlkeIRKAIGVCPQHNVQFDAlTVKENLtLFAkikgiLPQDVEQEVQQI-LSELDmqniRD- 609
Cdd:PLN03130 668 PPRSDASVV-------------IRGTVAYVPQVSWIFNA-TVRDNI-LFG-----SPFDPERYERAIdVTALQ----HDl 723
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 610 ------DLAE------HLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDP-FSRQRIWGFLK-ERRADHVILFSTQ--FM 673
Cdd:PLN03130 724 dllpggDLTEigergvNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAhVGRQVFDKCIKdELRGKTRVLVTNQlhFL 803
|
250 260
....*....|....*....|...
gi 568976233 674 DEadilADRKVLIANGALKCTGS 696
Cdd:PLN03130 804 SQ----VDRIILVHEGMIKEEGT 822
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
615-689 |
5.70e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 39.27 E-value: 5.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 615 LSEGQKRKLT----FGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFST----QFMDEADILADRKVLI 686
Cdd:cd03227 78 LSGGEKELSAlaliLALASLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIVIthlpELAELADKLIHIKKVI 157
|
...
gi 568976233 687 ANG 689
Cdd:cd03227 158 TGV 160
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
466-664 |
6.33e-03 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 41.23 E-value: 6.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 466 EPVDPEYQGKEAIRIRNIKKEYKGKSGKVK-------ALKGLFLDIYESQITAILGHSGAGKSS----LLNILsglyvPT 534
Cdd:PRK15134 264 DPVPLPEPASPLLDVEQLQVAFPIRKGILKrtvdhnvVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NS 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 535 AGSVTVYNKNLS--DMQDLKEIRKAIGVC---------PQHNVQfdaLTVKENLTLFAKIkgILPQDVEQEVQQILSE-- 601
Cdd:PRK15134 339 QGEIWFDGQPLHnlNRRQLLPVRHRIQVVfqdpnsslnPRLNVL---QIIEEGLRVHQPT--LSAAQREQQVIAVMEEvg 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568976233 602 LDMQNiRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADH 664
Cdd:PRK15134 414 LDPET-RHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKH 475
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
462-540 |
7.55e-03 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 40.69 E-value: 7.55e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568976233 462 DEYFEPVDPEYqGKEAIRIRNIKKEYKGKSgkvkALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTV 540
Cdd:TIGR03719 308 AEIYIPPGPRL-GDKVIEAENLTKAFGDKL----LIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI 381
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
1295-1532 |
1.00e-02 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 40.60 E-value: 1.00e-02
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1295 SRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAgqvelkRLSSAVGHQGDSRAEF------GYCPQ 1368
Cdd:PLN03140 173 AKKTKLTILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSL------KVSGEITYNGYRLNEFvprktsAYISQ 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1369 ENGLWPNLTVKEHLELYAAVKGL------------RKEDAVV-----------------AISRLVN--ALKL------HD 1411
Cdd:PLN03140 247 NDVHVGVMTVKETLDFSARCQGVgtrydllselarREKDAGIfpeaevdlfmkatamegVKSSLITdyTLKIlgldicKD 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568976233 1412 QL--NVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLA-EAEALCD 1488
Cdd:PLN03140 327 TIvgDEMIRGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMSLLQPApETFDLFD 406
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 568976233 1489 RAAIMVSGRLRCIGPIQHL------------KRKFGQDYVLELRVKDVSQEPLVHR 1532
Cdd:PLN03140 407 DIILLSEGQIVYQGPRDHIleffescgfkcpERKGTADFLQEVTSKKDQEQYWADR 462
|
|
| |
