hypothetical protein RFI_06043, partial [Reticulomyxa filosa]
Protein Classification
GAS domain-containing protein( domain architecture ID 708505)
GAS (growth-arrest specific micro-tubule binding) domain-containing protein similar to Drosophila melanogaster hermaphrodite
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| GAS super family | cl25894 | Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
68-264 | 1.47e-15 | ||||
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells. The actual alignment was detected with superfamily member pfam13851: Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 74.17 E-value: 1.47e-15
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| Name | Accession | Description | Interval | E-value | ||||
| GAS | pfam13851 | Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
68-264 | 1.47e-15 | ||||
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells. Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 74.17 E-value: 1.47e-15
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| Name | Accession | Description | Interval | E-value | ||||
| GAS | pfam13851 | Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
68-264 | 1.47e-15 | ||||
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells. Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 74.17 E-value: 1.47e-15
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