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Conserved domains on  [gi|589144242|ref|YP_009003546|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Indotyphlus maharashtraensis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009550)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-167 1.33e-68

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214415  Cd Length: 172  Bit Score: 205.47  E-value: 1.33e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242  81 AWGNWSVAFYISMYLGILMIGLNLLEEEDIECVI-----GEFSIIRCDWGGVSMMYCTGGLVLLILGWVLLMTLFVVLEL 155
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLftnydTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 589144242 156 IRVIGRGAVCAV 167
Cdd:MTH00065 161 TRGLSRGSLRAV 172
 
Name Accession Description Interval E-value
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-167 1.33e-68

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 205.47  E-value: 1.33e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242  81 AWGNWSVAFYISMYLGILMIGLNLLEEEDIECVI-----GEFSIIRCDWGGVSMMYCTGGLVLLILGWVLLMTLFVVLEL 155
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLftnydTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 589144242 156 IRVIGRGAVCAV 167
Cdd:MTH00065 161 TRGLSRGSLRAV 172
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-155 7.29e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 51.35  E-value: 7.29e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   17 VGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAM-AAEPYPEAWGNWSVAFYISMYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 589144242   96 GIL--MIGLNLLEEEDIECVIGEFSIIRCDWGGVSMMYcTGGLVLLILGWVLLMTLFVVLEL 155
Cdd:pfam00499  81 LLLalLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFT-DYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-167 1.33e-68

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 205.47  E-value: 1.33e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242  81 AWGNWSVAFYISMYLGILMIGLNLLEEEDIECVI-----GEFSIIRCDWGGVSMMYCTGGLVLLILGWVLLMTLFVVLEL 155
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLftnydTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 589144242 156 IRVIGRGAVCAV 167
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-167 2.55e-64

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 194.59  E-value: 2.55e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242  81 AWGNWSVAFYISMYLGILMIGLNLLEEEDIE------CVIGEFSIIRCDWGGVSMMYCTGGLVLLILGWVLLMTLFVVLE 154
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEgswvvvDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 589144242 155 LIRVIGRGAVCAV 167
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-167 4.57e-42

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 138.34  E-value: 4.57e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242  81 AWGNWSVAFYISMYLGILMI-------GLNLLEEEDIECVIGEFSIIRCDWGGVSMMYCTGGLVLLILGWVLLMTLFVVL 153
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVvgvvvggLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 589144242 154 ELIRVIGRGAVCAV 167
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-157 4.54e-32

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 112.59  E-value: 4.54e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242  81 AWG-NWSV--AFYISMYLGILMIGLnLLEEEDIECVI-------------GEFSIIRCDWGGVSMMYCTGGLVLLILGWV 144
Cdd:MTH00109  82 TWVsNKVVlgALLLGLLMELLLVLY-VLKDDEVEVVFnfnglgdwviydtGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|...
gi 589144242 145 LLMTLFVVLELIR 157
Cdd:MTH00109 161 LFIGVFVIIEITR 173
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-163 3.70e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 94.67  E-value: 3.70e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242  81 AWGNWSVAFYISMY-LGILMIGLNLLEEEDIECVIGEFSIIRCDWGGVSMMYCTGGLVLLILGWVLLMTLFVVLELIRVI 159
Cdd:MTH00214  81 SWGGWSVLLFFLFYlLGLGFVGFYFYGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLELVRGL 160


                 ....
gi 589144242 160 GRGA 163
Cdd:MTH00214 161 SRGA 164
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 4-161 2.97e-17

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 74.17  E-value: 2.97e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   4 VIILGLIGLMLGMVGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAAEPYPEAwG 83
Cdd:MTH00045   2 VFYLFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSV-S 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 589144242  84 NWSVAFYISMYLGILMIglnLLEEEDIECVIGEFSIIR-CDWGGVSMMYCTGGLVLLILGWVLLMTLFVVLELIRVIGR 161
Cdd:MTH00045  81 NLGEVLVLSLLLSLWVF---ISFDNFLELSNNNWSLVSlSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEY 156
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-155 7.29e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 51.35  E-value: 7.29e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   17 VGVASNPSPYFGALGLVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAM-AAEPYPEAWGNWSVAFYISMYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 589144242   96 GIL--MIGLNLLEEEDIECVIGEFSIIRCDWGGVSMMYcTGGLVLLILGWVLLMTLFVVLEL 155
Cdd:pfam00499  81 LLLalLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFT-DYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-152 8.28e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 35.25  E-value: 8.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144242   1 MEYVIILGLIGLMLGMVGVASNPSPYFGALglVMSAAAGCWVLVGLGMSFLSLVLFLIYLGGMLVVFAYSAAMAA-EPYP 79
Cdd:MTH00152   1 MSLMILLSVCFSLFLLLPLSKQPLSLGLVL--LLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPnPLFG 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 589144242  80 EAWGNWSVAFYISMYLGILMIGLNLLEEEDIECVIGEFSIIRCDWGGVSMMYCTGGLVLLILGWVLLMTLFVV 152
Cdd:MTH00152  79 SNFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSSLFDGSSGSLSFGGGLYSSSGWSIFVFLAVLLLIVMVSV 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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