|
Name |
Accession |
Description |
Interval |
E-value |
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
86-830 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 570.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 86 IEKIQAFEKFFTRHIdlYdKDEI-------ERKGSILVDFKELTKADeitnliPDIENALRDAPEKTLACMGLAIHQVLT 158
Cdd:COG1241 3 SDLVDKFEEFLRRYK--Y-RDEIlelaqeyPEKRSLVVDYNDLYSFD------PDLADDLLENPDEVLEAAEEALREIDL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 159 KDLErhaaelqaqeglsnggetmVNVPHIYARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAAC 238
Cdd:COG1241 74 EPYD-------------------VSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRC 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 239 GEIQSFPLPDGKYTLPTKCPVpaC-RGRSFAPLRSSplTVTLDWQLIKIQELMSDAqrEAGRIPRTIECELVHDLVDSCV 317
Cdd:COG1241 135 GTETYVPQTGEKLQEPHECPG--CgRQGPFKLLPEK--SEFIDAQKIRIQEPPEDL--PGGQQPQSIDVILEDDLVGEVR 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 318 PGDTVTVTGIVKvsnSEEGSRNKNDKCMFLLYIEANSVSnskgPKAQTAEDgckhgtlMEFSLKDLYAIREIQAEENLLK 397
Cdd:COG1241 209 PGDRVTVTGILR---IEQRTSGRGKSTIFDLYLEANSIE----VEEKEFEE-------IEITEEDEEKIKELSKDPDIYE 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:COG1241 275 KIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRI--RGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTA 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDS-SSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANP 555
Cdd:COG1241 353 AGLTAAAVRDDfGTGRWTLEAGALVLADGGLACIDELDKMREEDRsALHEAMEQQTISIAKAGIVATLNARCSVLAAANP 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 556 VGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHviairagkqkavssatvtrvlsqdsntsVLEVVS 635
Cdd:COG1241 433 KYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARH----------------------------ILKVHR 484
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 636 EKPLSERLKVAPGEQTDP-IPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSS-PITTRQLESLIRLT 713
Cdd:COG1241 485 AGELLEQEIEEETEEVKPeIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPvPITARQLEALIRLA 564
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 714 EARARLELREEATREDAEDIIEIMKHSMLGTYSD-EFGNLDFERSQHGSGMSNRSTAKRFISALNSIAERtYNNIFQYHQ 792
Cdd:COG1241 565 EASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDpETGKFDIDVIETGTSKSQRDKMKLIKDIIKELEEE-SSGGAPIED 643
|
730 740 750
....*....|....*....|....*....|....*...
gi 597517921 793 LRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQL 830
Cdd:COG1241 644 VIEEAEEEGIDREKAEELIEKLKRKGEIYEPKPGHYKK 681
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
398-740 |
0e+00 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 543.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVG 557
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 558 GHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHviairagkqkavssatvtrvlsqdsntsvlevvsek 637
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH------------------------------------ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 638 plserlkvapgeqtdpipHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEARA 717
Cdd:cd17759 205 ------------------HQLLRKYISYARQYVNPVLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLTEARA 266
|
330 340
....*....|....*....|...
gi 597517921 718 RLELREEATREDAEDIIEIMKHS 740
Cdd:cd17759 267 RLELREEATKEDAEDVIEIMKES 289
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
398-740 |
1.10e-157 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 462.20 E-value: 1.10e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDknRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILED--GTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV 556
Cdd:cd17706 79 AGLTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRtALHEAMEQQTISIAKAGIVTTLNARCSILAAANPK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 557 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVssatvtrvlsqdsntsvlevvse 636
Cdd:cd17706 159 GGRYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEE----------------------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 637 kplserlKVAPGEQTDPIPHQLLRKYIGYARQyVHPRLSTDAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEAR 716
Cdd:cd17706 216 -------QVKPEEDGIPIDIELLRKYILYARQ-IHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAH 287
|
330 340
....*....|....*....|....
gi 597517921 717 ARLELREEATREDAEDIIEIMKHS 740
Cdd:cd17706 288 AKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
200-742 |
2.42e-157 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 468.66 E-value: 2.42e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 200 LKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFPLPDGKYTLPTKCPVPACRGRSFAPLRSSpLTVTL 279
Cdd:smart00350 5 IRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTPFSLNHE-RSTFI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 280 DWQLIKIQELMSDAQreAGRIPRTIECELVHDLVDSCVPGDTVTVTGIVKVSNSEEGSRNKNDKCMFLLYIEANSVsnsK 359
Cdd:smart00350 84 DFQKIKLQESPEEVP--VGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVKGLPVFATYIEANHV---R 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 360 GPKAQTAEDGCkHGTLMEFSLKDLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRG 439
Cdd:smart00350 159 KLDYKRSFEDS-SFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKI--RG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 440 DPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQ 519
Cdd:smart00350 236 DINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 520 HQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLL 598
Cdd:smart00350 316 DRtAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDREL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 599 SEHVIAIragkqkavssatvtRVLSQDSNTSVLEVvsekplserlkvapgeqtdPIPHQLLRKYIGYARQYVHPRLSTDA 678
Cdd:smart00350 396 AKHVVDL--------------HRYSHPEEDEAFEP-------------------PLSQEKLRKYIAYAREKIKPKLSEEA 442
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 597517921 679 AQALQDFYLELRK---QSQRVGSSPITTRQLESLIRLTEARARLELREEATREDAEDIIEIMKHSML 742
Cdd:smart00350 443 ADKLVKAYVDLRKedsQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
398-737 |
1.88e-115 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 352.91 E-value: 1.88e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:cd17761 2 KIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRI--RGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV 556
Cdd:cd17761 80 AGLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRsALHEAMEQQTISIAKAGIVATLNARAAVLAAANPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 557 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQkavssatvtrvlsqdsntsvlevvse 636
Cdd:cd17761 160 FGRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGE-------------------------- 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 637 kplserlkvaPGEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSS-PITTRQLESLIRLTEA 715
Cdd:cd17761 214 ----------MREIKPEIDPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPSPvPITARQLEALVRLSEA 283
|
330 340
....*....|....*....|..
gi 597517921 716 RARLELREEATREDAEDIIEIM 737
Cdd:cd17761 284 SARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
382-606 |
2.02e-114 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 347.21 E-value: 2.02e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 382 DLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAAC 461
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRL--RGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 462 NVAPRGVYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQ-HQALLEAMEQQSISLAKAGVV 540
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEdRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597517921 541 CSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIR 606
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
399-740 |
9.66e-107 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 330.95 E-value: 9.66e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 399 VVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSS 478
Cdd:cd17753 2 IINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRI--RGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 479 GLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVG 557
Cdd:cd17753 80 GLTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRtSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 558 GHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKavssatvtrvlSQDSNTSVLEVVSEK 637
Cdd:cd17753 160 GRYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHP-----------ENDEDREGEEEKNQR 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 638 PLSERLKVapgeqtDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEARA 717
Cdd:cd17753 229 QRPKETKV------EPIPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHA 302
|
330 340
....*....|....*....|...
gi 597517921 718 RLELREEATREDAEDIIEIMKHS 740
Cdd:cd17753 303 KMHLREYVSEEDVDMAIRVMLDS 325
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
400-740 |
1.90e-102 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 319.31 E-value: 1.90e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 400 VNSLCPVIFGHELVKAGLTLALFGGSQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSG 479
Cdd:cd17757 3 VRSIAPSIYGHEEVKKGILLMLLGGVHKITREG--ISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 480 LTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGG 558
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQvAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 559 HYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVSSatvtrvlsqdsntsvlevvsekp 638
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAIEP----------------------- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 639 lserlkvapgeqtdPIPHQLLRKYIGYARQyVHPRLSTDAAQALQDFYLELRKQSQRVGSSP---ITTRQLESLIRLTEA 715
Cdd:cd17757 218 --------------PFTAEQLKRYIAYART-FKPKLTKEAKDELVEQYKELRQDDASGSTRSsyrITVRQLESLIRLSEA 282
|
330 340
....*....|....*....|....*
gi 597517921 716 RARLELREEATREDAEDIIEIMKHS 740
Cdd:cd17757 283 IARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
398-738 |
5.03e-101 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 315.53 E-value: 5.03e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKyADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRK-DFTKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCSLPARTSIIAAANPV 556
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLhEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 557 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIragkqkavssatvtrvlsqdsntsvleVVSE 636
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSL---------------------------YLED 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 637 KPLSerlkvapgEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQ-SQRVGSSPITTRQLESLIRLTEA 715
Cdd:cd17755 213 TPEH--------IQDEVLDVEVLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKMgSDARKRITATPRQLESLIRLAEA 284
|
330 340
....*....|....*....|...
gi 597517921 716 RARLELREEATREDAEDIIEIMK 738
Cdd:cd17755 285 HAKMRLSNVVEAEDVEEAVRLIR 307
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
398-740 |
8.64e-100 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 312.39 E-value: 8.64e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRL--RGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMgNQHQ--ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANP 555
Cdd:cd17756 79 AGLTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKM-REDDrvAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 556 VGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVSSatvtrvlsqdsntsvlevvs 635
Cdd:cd17756 158 VFGRYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQS-------------------- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 636 ekplserlkvapGEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQ-------SQRVGSSPITTRQLES 708
Cdd:cd17756 218 ------------QENEGEIPISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRKDvrqneleSDNRSSIPITVRQLEA 285
|
330 340 350
....*....|....*....|....*....|..
gi 597517921 709 LIRLTEARARLELREEATREDAEDIIEIMKHS 740
Cdd:cd17756 286 IIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
402-740 |
1.88e-92 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 292.78 E-value: 1.88e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 402 SLCPVIFGHELVKAGLTLALFGGSQKYADDknrIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLT 481
Cdd:cd17758 5 SIAPEIYGHEDVKKALLLLLVGGVDKRGDG---MKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGLT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 482 VTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHY 560
Cdd:cd17758 82 AAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRtAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGRY 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 561 NKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHviairagkqkavssatVTRVLSQDsntsvlevvsekpls 640
Cdd:cd17758 162 NPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEH----------------VTYVHQHN--------------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 641 erlkVAPGEQTDPIPHQLLRKYIGYARQYvHPRLSTDAAQALQDFYLELRKQSQRVGSSPITT-RQLESLIRLTEARARL 719
Cdd:cd17758 211 ----KQPDSDFEPLDPKLLRAYIALAKRK-RPTVPPALADYIVQAYVEMRQEAKRSKDFTFTTpRTLLAILRLSQALARL 285
|
330 340
....*....|....*....|.
gi 597517921 720 ELREEATREDAEDIIEIMKHS 740
Cdd:cd17758 286 RLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
398-740 |
2.14e-87 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 279.43 E-value: 2.14e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRV--RGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDssSGDFALEAGALVLGDQGICGIDEFDKMG-NQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPv 556
Cdd:cd17760 79 AGLTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKeHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 557 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEhviairagkqkavssatvtRVLSQDSNTSVLEVVse 636
Cdd:cd17760 156 KGQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISS-------------------FILENKGEPSKSSKL-- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 637 kplserlkvapgeqtdpIPHQLLRKYIGYARQyVHPRLSTDAAQALQDFYlELRKQSQRVGSSPITTRQLESLIRLTEAR 716
Cdd:cd17760 215 -----------------WSMEKMRTYFCLIKN-LRPVLSDEANAILLRYY-QLQRQSDCRNAARTTIRMLESLIRLAEAH 275
|
330 340
....*....|....*....|....
gi 597517921 717 ARLELREEATREDAEDIIEIMKHS 740
Cdd:cd17760 276 ARLMFRETVTEEDAITVVSVMESS 299
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
58-760 |
1.03e-81 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 281.50 E-value: 1.03e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 58 QQSTLDQFIPYKGWKL--YFSEVYSNNSPFIEKIQAFEKFFTrHIDLYDKDEIErkgsILVDFKELTKAdEITNLIPDIE 135
Cdd:PTZ00111 112 QQSKPEYTELYYLWKLmnFIKENLRDHSTGYSRILPFEVDLM-HVYSFDKVLYK----LLVTFPADCIA-ELDKVLVKLF 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 136 NALrdapektlacmglaihqvltkdLERHAAELQAQEglsnggetmvNVPHIYARVYNYEPLTHLKNIRATCYGKYISIR 215
Cdd:PTZ00111 186 NEL----------------------LSKHYSDLSLEN----------NSFFPRARLMNKPVSDCVGNLEPSMADSLVQFS 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 216 GTVVRVSNIKPLCTNMAFQCAA-----------CGEIQSFPLPDGKYTLPTKCPvpACRGRSFAPLRSSpLTVTLDWQLI 284
Cdd:PTZ00111 234 GTVVRQTWIVPEITMACFRCRGqkkiglndyqpCTCEHYEYVIQGEVNEPLLCN--ECNSKYTFELNHN-MCVYSTKKIV 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 285 KIQELMS--------------DAQREAGRI----PRTIECELVHDLVDSCVPGDTVTVTGIVKVSNSEEGSRNKNDKCMF 346
Cdd:PTZ00111 311 KLLQSNSslnnpdkdgldnsvDNSGLNGEIymkdNEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTSTTRRTLKSLY 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 347 LLYIEANSVSNSKGPKAQTAEDGCKH-GTLMEFSLKDLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGS 425
Cdd:PTZ00111 391 TYFVNVIHVKVINSTNANQPEKGLKYlGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGN 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 426 qKYADDKNRIP--------IRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLTVTLS-KDSSSGDFALE 496
Cdd:PTZ00111 471 -KNSSDFNKSPdacykvdnFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQ 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 497 AGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKARTVSENLKMGSA 575
Cdd:PTZ00111 550 PGAVVLANGGVCCIDELDKCHNESRLSLyEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPS 629
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 576 LLSRFDLVFILLDTPNEQHDHLLSEhVIA--IRAGKQKAVSSATVTrvlSQDSNTSVLEvvsekplSERLKvaPGEQTDP 653
Cdd:PTZ00111 630 LFTRFDLIYLVLDHIDQDTDQLISL-SIAkdFLLPHMTGSGNDEDT---YDRSNTMHVE-------DESLR--SEKDYNK 696
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 654 IPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQS----------------------QRVGSSPIT--TRQLESL 709
Cdd:PTZ00111 697 NDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyQSSGTRMIYvsSRMISSI 776
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 597517921 710 IRLTEARARLELREEATREDAEDIIEIMKHSMLGTYSDEF-GNLDFERSQHG 760
Cdd:PTZ00111 777 IRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTtGKIDFDQLHQG 828
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
398-738 |
2.44e-79 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 257.78 E-value: 2.44e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 398 LVVNSLCPVIFGHELVKAGLTLALFGGSQKyaDDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 477
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEK--NLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 478 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV 556
Cdd:cd17754 79 VGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRvAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 557 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRagkqkavssatvtRVLsqdsntsvlevvse 636
Cdd:cd17754 159 YGRYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMH-------------RYI-------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 637 kplserlkvapgeqtdpiphQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQ----SQRVGSSPITTRQLESLIRL 712
Cdd:cd17754 212 --------------------KFLRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNDdntkTDKARTSPITARTLETLIRL 271
|
330 340
....*....|....*....|....*.
gi 597517921 713 TEARARLELREEATREDAEDIIEIMK 738
Cdd:cd17754 272 ATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
657-741 |
1.21e-35 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 129.59 E-value: 1.21e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 657 QLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSS-PITTRQLESLIRLTEARARLELREEATREDAEDIIE 735
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTGSGSSiPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80
|
....*.
gi 597517921 736 IMKHSM 741
Cdd:pfam17855 81 LLKESL 86
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
199-330 |
4.13e-32 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 121.05 E-value: 4.13e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 199 HLKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFplpdgKYTLPTKCPVPACRGRSfaPLRSSP-LTV 277
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGV-----KITEPTKCPNPECGNKD--PFKLVHeKSK 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 597517921 278 TLDWQLIKIQElMSDaQREAGRIPRTIECELVHDLVDSCVPGDTVTVTGIVKV 330
Cdd:pfam17207 74 FVDFQKIKIQE-SPE-EVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRV 124
|
|
| MCM8_WHD |
cd22247 |
winged-helix domain (WHD) found in minichromosome maintenance 8 (MCM8) and similar proteins; ... |
766-831 |
1.13e-30 |
|
winged-helix domain (WHD) found in minichromosome maintenance 8 (MCM8) and similar proteins; MCM8 is a DNA helicase that is a component of the MCM8-MCM9 complex, which is involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR). The MCM8-MCM9 complex is also required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting its nuclease activity. This model corresponds to the C-terminal winged-helix domain (WHD) of MCM8, which mediates protein-nucleic acid interaction, as well as protein-protein interaction.
Pssm-ID: 439328 [Multi-domain] Cd Length: 66 Bit Score: 114.89 E-value: 1.13e-30
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597517921 766 RSTAKRFISALNSIAERTYNNIFQYHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQLQ 831
Cdd:cd22247 1 RKQAKRFVSALQREAERKGNNLFTVDELKQIAKELGLQVDDFDDFIESLNNQGYLLKKGPNLYQLQ 66
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
442-753 |
1.57e-10 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 62.88 E-value: 1.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 442 HVLIVGDPGLGKSQMLQAacnVAprgvyvcgnttTSSGL-------TVTL--SK-------DSSSGDFALEAGAL----V 501
Cdd:COG0714 33 HLLLEGVPGVGKTTLAKA---LA-----------RALGLpfiriqfTPDLlpSDilgtyiyDQQTGEFEFRPGPLfanvL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 502 LgdqgicgIDEFDKMGNQHQ-ALLEAMEQQSISLakAGVVCSLPARTSIIAAANPVGghynKART--VSEnlkmgsALLS 578
Cdd:COG0714 99 L-------ADEINRAPPKTQsALLEAMEERQVTI--PGGTYKLPEPFLVIATQNPIE----QEGTypLPE------AQLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 579 RFdLVFILLDTPNEqhdhllsEHVIAIRAGKQkAVSSATVTRVLSQDSNTSVLEVVSEKPLSERLKvapgeqtdpiphql 658
Cdd:COG0714 160 RF-LLKLYIGYPDA-------EEEREILRRHT-GRHLAEVEPVLSPEELLALQELVRQVHVSEAVL-------------- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 659 lrkyiGYARQYVHprlstdaaqalqdfylELRKQSQ-RVGSSPittRQLESLIRLTEARARLELREEATREDAEDIIE-I 736
Cdd:COG0714 217 -----DYIVDLVR----------------ATREHPDlRKGPSP---RASIALLRAARALALLDGRDYVTPDDVKAVAGpV 272
|
330
....*....|....*..
gi 597517921 737 MKHSMLGTYSDEFGNLD 753
Cdd:COG0714 273 LKHRLILSPEADAEGVT 289
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
428-586 |
4.24e-07 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 50.22 E-value: 4.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 428 YADDKNRIPIRGDPHVLIVGDPGLGKSQMLQA-ACNVAPRGVYVCgnTTTSSGLTVTLSKDSSSGDFALEA--GALVLGD 504
Cdd:cd00009 7 IEALREALELPPPKNLLLYGPPGTGKTTLARAiANELFRPGAPFL--YLNASDLLEGLVVAELFGHFLVRLlfELAEKAK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 505 QGICGIDEFDKMGNQ-HQALLEAMEQQSISLAKagvvcslPARTSIIAAANPvgghynkartvSENLKMGSALLSRFDLV 583
Cdd:cd00009 85 PGVLFIDEIDSLSRGaQNALLRVLETLNDLRID-------RENVRVIGATNR-----------PLLGDLDRALYDRLDIR 146
|
...
gi 597517921 584 FIL 586
Cdd:cd00009 147 IVI 149
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
442-580 |
1.82e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 44.98 E-value: 1.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 442 HVLIVGDPGLGKSQMLQaacnvaprgvYVCGNTTTSSGLTVTLSKDSSSGDF-----------ALEAGALVLGDQ--GIC 508
Cdd:pfam07728 1 GVLLVGPPGTGKTELAE----------RLAAALSNRPVFYVQLTRDTTEEDLfgrrnidpggaSWVDGPLVRAARegEIA 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 597517921 509 GIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPA-RTSIIAAANPVGghynkaRTVSEnlkMGSALLSRF 580
Cdd:pfam07728 71 VLDEINRANPDVLnSLLSLLDERRLLLPDGGELVKAAPdGFRLIATMNPLD------RGLNE---LSPALRSRF 135
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
496-728 |
9.65e-05 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 45.74 E-value: 9.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 496 EAGALVLGDQGICGIDEFDKMGNQH-QALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV-GGHY--NKARTVSENL- 570
Cdd:PRK09862 286 GPGEISLAHNGVLFLDELPEFERRTlDALREPIESGQIHLSRTRAKITYPARFQLVAAMNPSpTGHYqgNHNRCTPEQTl 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 571 ----KMGSALLSRFDLVF-ILLDTPNeqhdhLLSEHVIairagkqKAVSSATV-TRVLSQDSNtsvlEVVSEKPLSERLK 644
Cdd:PRK09862 366 rylnRLSGPFLDRFDLSLeIPLPPPG-----ILSKTVV-------PGESSATVkQRVMAARER----QFKRQNKLNAWLD 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 645 VAPgeqtdpiphqlLRKYIgyarqyvhpRLSTDAAQALQDFYLELrkqsqrvgssPITTRQLESLIRLTEARARLELREE 724
Cdd:PRK09862 430 SPE-----------IRQFC---------KLESEDARWLEETLIHL----------GLSIRAWQRLLKVARTIADIDQSDI 479
|
....
gi 597517921 725 ATRE 728
Cdd:PRK09862 480 ITRQ 483
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
443-472 |
5.16e-04 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 42.90 E-value: 5.16e-04
10 20 30
....*....|....*....|....*....|....
gi 597517921 443 VLIVGDPGLGKSQ-MLQAACNVAPRG---VYVCG 472
Cdd:cd01121 85 VLIGGDPGIGKSTlLLQVAARLAQRGgkvLYVSG 118
|
|
| Sms |
COG1066 |
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and ... |
443-472 |
1.14e-03 |
|
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and repair];
Pssm-ID: 440685 [Multi-domain] Cd Length: 453 Bit Score: 42.34 E-value: 1.14e-03
10 20 30
....*....|....*....|....*....|....
gi 597517921 443 VLIVGDPGLGKSQ-MLQAACNVAPRG---VYVCG 472
Cdd:COG1066 92 VLIGGEPGIGKSTlLLQVAARLAKKGgkvLYVSG 125
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
442-588 |
6.60e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.12 E-value: 6.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597517921 442 HVLIVGDPGLGKSQMLQAACNVAPRG----VYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLG--------DQGICG 509
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPgggvIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLalalarklKPDVLI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 597517921 510 IDEFDKMGNQHQALLEAMEQQSISLAKAgvvcSLPARTSIIAAANPvgghynkartvsENLKMGSALLSRFDLVFILLD 588
Cdd:smart00382 84 LDEITSLLDAEQEALLLLLEELRLLLLL----KSEKNLTVILTTND------------EKDLGPALLRRRFDRRIVLLL 146
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
443-480 |
9.25e-03 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 38.78 E-value: 9.25e-03
10 20 30
....*....|....*....|....*....|....*....
gi 597517921 443 VLIVGDPGLGKSQMLQAACNVAPRGVYV-CGNTTTSSGL 480
Cdd:COG2842 53 GVVYGESGVGKTTAAREYANRNPNVIYVtASPSWTSKEL 91
|
|
| |
