NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|606920876|gb|EYZ54080|]
View 

hypothetical protein BW92_00090 [Escherichia coli O157:H7 str. 06-3745]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
DUF905 super family cl05514
Bacterial protein of unknown function (DUF905); This family consists of several short ...
10-77 1.41e-30

Bacterial protein of unknown function (DUF905); This family consists of several short hypothetical Enterobacteria proteins of unknown function. Structural analysis of the surface features of the protein YvyC has revealed a single cluster of highly conserved residues on the surface. Additionally, these residues fall into two groups which lie within the two largest of the three cavities identified over the surface. The conclusion from this is that these two cavities with, Leu 58, Glu 75, Ile 82, and Glu 83 and Pro 86, conserved, are likely to be important for the molecular function and reflect the cavities found on the surface of the FlaG proteins in pfam03646.


The actual alignment was detected with superfamily member pfam06006:

Pssm-ID: 368702  Cd Length: 70  Bit Score: 102.26  E-value: 1.41e-30
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 606920876  10 GLPDGPFTRKHAEAVAAQYRNVFIENDHGEQFRLVVRN-NGAMVWRTWNFEDGAGYWMNHVIRDFGIIK 77
Cdd:pfam06006  2 SLPDGTFTREQAQAVAAQYQNVAIEDDQGTHFRLVVRDaDGEMVWRAWNFEPGAGYWLNRYIRDYGIRK 70
 
Name Accession Description Interval E-value
DUF905 pfam06006
Bacterial protein of unknown function (DUF905); This family consists of several short ...
10-77 1.41e-30

Bacterial protein of unknown function (DUF905); This family consists of several short hypothetical Enterobacteria proteins of unknown function. Structural analysis of the surface features of the protein YvyC has revealed a single cluster of highly conserved residues on the surface. Additionally, these residues fall into two groups which lie within the two largest of the three cavities identified over the surface. The conclusion from this is that these two cavities with, Leu 58, Glu 75, Ile 82, and Glu 83 and Pro 86, conserved, are likely to be important for the molecular function and reflect the cavities found on the surface of the FlaG proteins in pfam03646.


Pssm-ID: 368702  Cd Length: 70  Bit Score: 102.26  E-value: 1.41e-30
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 606920876  10 GLPDGPFTRKHAEAVAAQYRNVFIENDHGEQFRLVVRN-NGAMVWRTWNFEDGAGYWMNHVIRDFGIIK 77
Cdd:pfam06006  2 SLPDGTFTREQAQAVAAQYQNVAIEDDQGTHFRLVVRDaDGEMVWRAWNFEPGAGYWLNRYIRDYGIRK 70
 
Name Accession Description Interval E-value
DUF905 pfam06006
Bacterial protein of unknown function (DUF905); This family consists of several short ...
10-77 1.41e-30

Bacterial protein of unknown function (DUF905); This family consists of several short hypothetical Enterobacteria proteins of unknown function. Structural analysis of the surface features of the protein YvyC has revealed a single cluster of highly conserved residues on the surface. Additionally, these residues fall into two groups which lie within the two largest of the three cavities identified over the surface. The conclusion from this is that these two cavities with, Leu 58, Glu 75, Ile 82, and Glu 83 and Pro 86, conserved, are likely to be important for the molecular function and reflect the cavities found on the surface of the FlaG proteins in pfam03646.


Pssm-ID: 368702  Cd Length: 70  Bit Score: 102.26  E-value: 1.41e-30
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 606920876  10 GLPDGPFTRKHAEAVAAQYRNVFIENDHGEQFRLVVRN-NGAMVWRTWNFEDGAGYWMNHVIRDFGIIK 77
Cdd:pfam06006  2 SLPDGTFTREQAQAVAAQYQNVAIEDDQGTHFRLVVRDaDGEMVWRAWNFEPGAGYWLNRYIRDYGIRK 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH