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Conserved domains on  [gi|62901127|sp|O48772|]
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RecName: Full=Zinc finger CCCH domain-containing protein 26; Short=AtC3H26; AltName: Full=Zinc finger CCCH domain-containing protein ZFN2

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 10457906)

zinc finger CCCH domain-containing protein similar to Sus scrofa proline-rich protein 3

Gene Ontology:  GO:0046872|GO:0003676
PubMed:  27990022|12665246
SCOP:  3001741

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
264-288 1.31e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.19  E-value: 1.31e-07
                          10        20
                  ....*....|....*....|....*
gi 62901127   264 RAECRFFMNTGTCKYGDDCKYSHPK 288
Cdd:pfam00642   3 TELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
130-155 6.21e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 6.21e-07
                          10        20
                  ....*....|....*....|....*.
gi 62901127   130 QGEKPCPYYMQTGLCRFGVACKFHHP 155
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
45-70 1.29e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.49  E-value: 1.29e-06
                          10        20
                  ....*....|....*....|....*.
gi 62901127    45 PGERDCQFFLRTGQCGYGNSCRYNHP 70
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
308-334 1.13e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 41.80  E-value: 1.13e-05
                          10        20
                  ....*....|....*....|....*..
gi 62901127   308 PGQPACGNFKAYGFCKFGANCKFDHSM 334
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
90-111 1.26e-03

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 36.02  E-value: 1.26e-03
                          10        20
                  ....*....|....*....|....*.
gi 62901127    90 GQPDC----ETGACKYGPTCKYHHPK 111
Cdd:pfam00642   2 KTELCrfflRTGYCKYGDRCKFAHGQ 27
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
264-288 1.31e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.19  E-value: 1.31e-07
                          10        20
                  ....*....|....*....|....*
gi 62901127   264 RAECRFFMNTGTCKYGDDCKYSHPK 288
Cdd:pfam00642   3 TELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
130-155 6.21e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 6.21e-07
                          10        20
                  ....*....|....*....|....*.
gi 62901127   130 QGEKPCPYYMQTGLCRFGVACKFHHP 155
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
45-70 1.29e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.49  E-value: 1.29e-06
                          10        20
                  ....*....|....*....|....*.
gi 62901127    45 PGERDCQFFLRTGQCGYGNSCRYNHP 70
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
308-334 1.13e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 41.80  E-value: 1.13e-05
                          10        20
                  ....*....|....*....|....*..
gi 62901127   308 PGQPACGNFKAYGFCKFGANCKFDHSM 334
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
265-288 1.18e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 39.15  E-value: 1.18e-04
                           10        20
                   ....*....|....*....|....
gi 62901127    265 AECRFFMnTGTCKYGDDCKYSHPK 288
Cdd:smart00356   5 ELCKFFK-RGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
129-156 5.67e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 5.67e-04
                           10        20
                   ....*....|....*....|....*...
gi 62901127    129 RQGEKPCPYYmQTGLCRFGVACKFHHPH 156
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
44-71 9.92e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.45  E-value: 9.92e-04
                           10        20
                   ....*....|....*....|....*...
gi 62901127     44 RPGERDCQFFlRTGQCGYGNSCRYNHPL 71
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
90-111 1.26e-03

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 36.02  E-value: 1.26e-03
                          10        20
                  ....*....|....*....|....*.
gi 62901127    90 GQPDC----ETGACKYGPTCKYHHPK 111
Cdd:pfam00642   2 KTELCrfflRTGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
307-334 2.73e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 35.30  E-value: 2.73e-03
                           10        20
                   ....*....|....*....|....*...
gi 62901127    307 RPGQPACGNFKaYGFCKFGANCKFDHSM 334
Cdd:smart00356   1 KYKTELCKFFK-RGYCPRGDRCKFAHPL 27
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
264-288 1.31e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 47.19  E-value: 1.31e-07
                          10        20
                  ....*....|....*....|....*
gi 62901127   264 RAECRFFMNTGTCKYGDDCKYSHPK 288
Cdd:pfam00642   3 TELCRFFLRTGYCKYGDRCKFAHGQ 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
130-155 6.21e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 6.21e-07
                          10        20
                  ....*....|....*....|....*.
gi 62901127   130 QGEKPCPYYMQTGLCRFGVACKFHHP 155
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
45-70 1.29e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 44.49  E-value: 1.29e-06
                          10        20
                  ....*....|....*....|....*.
gi 62901127    45 PGERDCQFFLRTGQCGYGNSCRYNHP 70
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHG 26
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
308-334 1.13e-05

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 41.80  E-value: 1.13e-05
                          10        20
                  ....*....|....*....|....*..
gi 62901127   308 PGQPACGNFKAYGFCKFGANCKFDHSM 334
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 267-286 3.72e-05

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 40.48  E-value: 3.72e-05
                          10        20
                  ....*....|....*....|
gi 62901127   267 CRFFMNtGTCKYGDDCKYSH 286
Cdd:pfam18345   1 CKFFLK-GRCRYGDKCRFAH 19
ZnF_C3H1 smart00356
zinc finger;
265-288 1.18e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 39.15  E-value: 1.18e-04
                           10        20
                   ....*....|....*....|....
gi 62901127    265 AECRFFMnTGTCKYGDDCKYSHPK 288
Cdd:smart00356   5 ELCKFFK-RGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
129-156 5.67e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 37.22  E-value: 5.67e-04
                           10        20
                   ....*....|....*....|....*...
gi 62901127    129 RQGEKPCPYYmQTGLCRFGVACKFHHPH 156
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
ZnF_C3H1 smart00356
zinc finger;
44-71 9.92e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 36.45  E-value: 9.92e-04
                           10        20
                   ....*....|....*....|....*...
gi 62901127     44 RPGERDCQFFlRTGQCGYGNSCRYNHPL 71
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAHPL 27
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
90-111 1.26e-03

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 36.02  E-value: 1.26e-03
                          10        20
                  ....*....|....*....|....*.
gi 62901127    90 GQPDC----ETGACKYGPTCKYHHPK 111
Cdd:pfam00642   2 KTELCrfflRTGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
307-334 2.73e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 35.30  E-value: 2.73e-03
                           10        20
                   ....*....|....*....|....*...
gi 62901127    307 RPGQPACGNFKaYGFCKFGANCKFDHSM 334
Cdd:smart00356   1 KYKTELCKFFK-RGYCPRGDRCKFAHPL 27
zf-CCCH_4 pfam18044
CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and ...
 267-287 8.21e-03

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and one histidine to coordinate the zinc ion. This domain is found in a wide variety of proteins such as E3 ligases.


Pssm-ID: 465626  Cd Length: 22  Bit Score: 33.72  E-value: 8.21e-03
                          10        20
                  ....*....|....*....|.
gi 62901127   267 CRFFMnTGTCKYGDDCKYSHP 287
Cdd:pfam18044   3 CRYFQ-KGGCRYGDNCRFSHD 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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